Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	5-methylcytosine dioxygenase activity	TET2 TET1	3.73e-05	3	71	2	GO:0070579
Domain	Tet_JBP	TET2 TET1	1.42e-05	2	71	2	PF12851
Domain	2OGFeDO_noxygenase_dom	TET2 TET1	1.42e-05	2	71	2	IPR024779
Domain	Tgfb1i1/Leupaxin	TGFB1I1 LPXN	1.42e-05	2	71	2	IPR017305
Domain	Tet_JBP	TET2 TET1	1.42e-05	2	71	2	SM01333
Domain	EGF_3	SELE MUC3B CNTNAP4 ADGRE5 EDIL3 NOTCH3 STAB1	3.06e-05	235	71	7	PS50026
Domain	EGF	SELE MUC3B CNTNAP4 ADGRE5 EDIL3 NOTCH3 STAB1	3.06e-05	235	71	7	SM00181
Domain	SV2	SV2B SV2A	4.26e-05	3	71	2	IPR022308
Domain	Pentapeptide_4	SV2B SV2A	4.26e-05	3	71	2	PF13599
Domain	EGF-like_dom	SELE MUC3B CNTNAP4 ADGRE5 EDIL3 NOTCH3 STAB1	4.43e-05	249	71	7	IPR000742
Domain	EGF-like_CS	SELE MUC3B EPHA2 CNTNAP4 EDIL3 NOTCH3 STAB1	5.96e-05	261	71	7	IPR013032
Domain	EGF_2	SELE MUC3B EPHA2 CNTNAP4 EDIL3 NOTCH3 STAB1	6.56e-05	265	71	7	PS01186
Domain	5peptide_repeat	SV2B SV2A	8.51e-05	4	71	2	IPR001646
Domain	EGF	SELE CNTNAP4 EDIL3 NOTCH3 STAB1	1.18e-04	126	71	5	PF00008
Domain	EGF_1	SELE MUC3B CNTNAP4 EDIL3 NOTCH3 STAB1	4.17e-04	255	71	6	PS00022
Domain	EGF_CA	ADGRE5 EDIL3 NOTCH3 STAB1	1.20e-03	122	71	4	SM00179
Domain	EGF-like_Ca-bd_dom	ADGRE5 EDIL3 NOTCH3 STAB1	1.28e-03	124	71	4	IPR001881
Domain	EGF_extracell	EDIL3 NOTCH3 STAB1	1.54e-03	60	71	3	IPR013111
Domain	EGF_2	EDIL3 NOTCH3 STAB1	1.54e-03	60	71	3	PF07974
Domain	RCC1	RCBTB1 RCBTB2	2.59e-03	20	71	2	PF00415
Domain	-	EPHA2 CNTNAP4 EDIL3	2.71e-03	73	71	3	2.60.120.260
Domain	FA58C	CNTNAP4 EDIL3	2.86e-03	21	71	2	SM00231
Domain	RCC1_1	RCBTB1 RCBTB2	2.86e-03	21	71	2	PS00625
Domain	RCC1_2	RCBTB1 RCBTB2	2.86e-03	21	71	2	PS00626
Domain	RCC1_3	RCBTB1 RCBTB2	2.86e-03	21	71	2	PS50012
Domain	FA58C_3	CNTNAP4 EDIL3	2.86e-03	21	71	2	PS50022
Domain	FA58C_1	CNTNAP4 EDIL3	2.86e-03	21	71	2	PS01285
Domain	FA58C_2	CNTNAP4 EDIL3	2.86e-03	21	71	2	PS01286
Domain	Growth_fac_rcpt_	EPHA2 ADGRE5 NOTCH3 STAB1	2.95e-03	156	71	4	IPR009030
Domain	Reg_chr_condens	RCBTB1 RCBTB2	3.13e-03	22	71	2	IPR000408
Domain	-	RCBTB1 RCBTB2	3.13e-03	22	71	2	2.130.10.30
Domain	RCC1/BLIP-II	RCBTB1 RCBTB2	3.42e-03	23	71	2	IPR009091
Domain	F5_F8_type_C	CNTNAP4 EDIL3	3.73e-03	24	71	2	PF00754
Domain	FA58C	CNTNAP4 EDIL3	3.73e-03	24	71	2	IPR000421
Domain	hEGF	EDIL3 NOTCH3	5.05e-03	28	71	2	PF12661
Domain	TNFR_NGFR_1	TNFRSF13B TNFRSF18	5.41e-03	29	71	2	PS00652
Domain	TNFR_NGFR_2	TNFRSF13B TNFRSF18	5.41e-03	29	71	2	PS50050
Domain	Galactose-bd-like	EPHA2 CNTNAP4 EDIL3	5.51e-03	94	71	3	IPR008979
Domain	EGF_Ca-bd_CS	ADGRE5 EDIL3 NOTCH3	6.01e-03	97	71	3	IPR018097
Domain	EGF_CA	ADGRE5 EDIL3 NOTCH3	6.36e-03	99	71	3	PS01187
Domain	ASX_HYDROXYL	ADGRE5 EDIL3 NOTCH3	6.54e-03	100	71	3	PS00010
Domain	Sugar_transporter_CS	SV2B SV2A	6.57e-03	32	71	2	IPR005829
Domain	TNFR/NGFR_Cys_rich_reg	TNFRSF13B TNFRSF18	6.97e-03	33	71	2	IPR001368
Domain	EGF-type_Asp/Asn_hydroxyl_site	ADGRE5 EDIL3 NOTCH3	7.68e-03	106	71	3	IPR000152
Domain	MFS_sugar_transport-like	SV2B SV2A	8.26e-03	36	71	2	IPR005828
Domain	Sugar_tr	SV2B SV2A	8.26e-03	36	71	2	PF00083
Pubmed	Distributive Processing by the Iron(II)/α-Ketoglutarate-Dependent Catalytic Domains of the TET Enzymes Is Consistent with Epigenetic Roles for Oxidized 5-Methylcytosine Bases.	TET2 TET1	4.59e-06	2	75	2	27362828
Pubmed	SV2 renders primed synaptic vesicles competent for Ca2+ -induced exocytosis.	SV2B SV2A	4.59e-06	2	75	2	19176798
Pubmed	Structural insight into substrate preference for TET-mediated oxidation.	TET2 TET1	4.59e-06	2	75	2	26524525
Pubmed	Decrease of 5-hydroxymethylcytosine and TET1 with nuclear exclusion of TET2 in small intestinal neuroendocrine tumors.	TET2 TET1	4.59e-06	2	75	2	30045709
Pubmed	Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.	TET2 TET1	4.59e-06	2	75	2	23415914
Pubmed	Synaptic vesicle protein 2 binds adenine nucleotides.	SV2B SV2A	4.59e-06	2	75	2	18524768
Pubmed	SV2 mediates entry of tetanus neurotoxin into central neurons.	SV2B SV2A	4.59e-06	2	75	2	21124874
Pubmed	Ten-Eleven Translocation Proteins Modulate the Response to Environmental Stress in Mice.	TET2 TET1	4.59e-06	2	75	2	30540950
Pubmed	Tet1 Deficiency Leads to Premature Reproductive Aging by Reducing Spermatogonia Stem Cells and Germ Cell Differentiation.	TET2 TET1	4.59e-06	2	75	2	32114381
Pubmed	Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development.	TET2 TET1	4.59e-06	2	75	2	35955629
Pubmed	Redox-active quinones induces genome-wide DNA methylation changes by an iron-mediated and Tet-dependent mechanism.	TET2 TET1	4.59e-06	2	75	2	24214992
Pubmed	Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells.	TET2 TET1	4.59e-06	2	75	2	24474761
Pubmed	Ten-eleven translocation protein 1 modulates medulloblastoma progression.	TET2 TET1	4.59e-06	2	75	2	33926529
Pubmed	Coordination of engineered factors with TET1/2 promotes early-stage epigenetic modification during somatic cell reprogramming.	TET2 TET1	4.59e-06	2	75	2	24672749
Pubmed	A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands.	TET2 TET1	4.59e-06	2	75	2	27288448
Pubmed	Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination.	TET2 TET1	4.59e-06	2	75	2	30606231
Pubmed	Ten-eleven translocation 2 modulates allergic inflammation by 5-hydroxymethylcytosine remodeling of immunologic pathways.	TET2 TET1	4.59e-06	2	75	2	34165552
Pubmed	Tet1 and Tet2 Protect DNA Methylation Canyons against Hypermethylation.	TET2 TET1	4.59e-06	2	75	2	26598602
Pubmed	SV2 regulates neurotransmitter release via multiple mechanisms.	SV2B SV2A	4.59e-06	2	75	2	20702688
Pubmed	Expression of CLLD7 and CHC1L Proteins in Oral Epithelial Dysplasia in a Group of Thai Patients.	RCBTB1 RCBTB2	4.59e-06	2	75	2	38679985
Pubmed	Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice.	TET2 TET1	4.59e-06	2	75	2	26586431
Pubmed	Synaptic vesicle protein 2 enhances release probability at quiescent synapses.	SV2B SV2A	4.59e-06	2	75	2	16436618
Pubmed	Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns.	TET2 TET1	4.59e-06	2	75	2	35075236
Pubmed	Altered balance between excitatory and inhibitory inputs onto CA1 pyramidal neurons from SV2A-deficient but not SV2B-deficient mice.	SV2B SV2A	4.59e-06	2	75	2	22847229
Pubmed	Tet-mediated imprinting erasure in H19 locus following reprogramming of spermatogonial stem cells to induced pluripotent stem cells.	TET2 TET1	4.59e-06	2	75	2	26328763
Pubmed	Ten-Eleven Translocation 1 and 2 Confer Overlapping Transcriptional Programs for the Proliferation of Cultured Adult Neural Stem Cells.	TET2 TET1	4.59e-06	2	75	2	27778125
Pubmed	Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.	SV2B SV2A	4.59e-06	2	75	2	18815274
Pubmed	Abnormal neurotransmission in mice lacking synaptic vesicle protein 2A (SV2A).	SV2B SV2A	4.59e-06	2	75	2	10611374
Pubmed	TET-dependent regulation of retrotransposable elements in mouse embryonic stem cells.	TET2 TET1	4.59e-06	2	75	2	27863519
Pubmed	Brain contains two forms of synaptic vesicle protein 2.	SV2B SV2A	4.59e-06	2	75	2	7681585
Pubmed	Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism.	TET2 TET1	4.59e-06	2	75	2	28783731
Pubmed	Novel Epigenetic Controlling of Hypoxia Pathway Related to Overexpression and Promoter Hypomethylation of TET1 and TET2 in RPE Cells.	TET2 TET1	4.59e-06	2	75	2	28252217
Pubmed	SV2A and SV2B function as redundant Ca2+ regulators in neurotransmitter release.	SV2B SV2A	4.59e-06	2	75	2	10624962
Pubmed	Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss.	TET2 TET1	1.37e-05	3	75	2	30074219
Pubmed	Induced DNA demethylation by targeting Ten-Eleven Translocation 2 to the human ICAM-1 promoter.	TET2 TET1	1.37e-05	3	75	2	24194590
Pubmed	PRDM14 maintains pluripotency of embryonic stem cells through TET-mediated active DNA demethylation.	TET2 TET1	1.37e-05	3	75	2	26325469
Pubmed	TET proteins in malignant hematopoiesis.	TET2 TET1	1.37e-05	3	75	2	19923888
Pubmed	Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells.	TET2 TET1	1.37e-05	3	75	2	31433977
Pubmed	Epigenomic analysis of gastrulation identifies a unique chromatin state for primed pluripotency.	TET2 TET1	1.37e-05	3	75	2	31844322
Pubmed	Selective targeting of TET catalytic domain promotes somatic cell reprogramming.	TET2 TET1	1.37e-05	3	75	2	32024762
Pubmed	Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs.	TET2 TET1	1.37e-05	3	75	2	27184841
Pubmed	Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis.	SV2B SV2A	1.37e-05	3	75	2	23617838
Pubmed	Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.	TET2 TET1	1.37e-05	3	75	2	24838012
Pubmed	Paxillin family proteins Hic-5 and LPXN promote lipid storage by regulating the ubiquitination degradation of CIDEC.	TGFB1I1 LPXN	1.37e-05	3	75	2	38159847
Pubmed	Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine.	TET2 TET1	1.37e-05	3	75	2	21778364
Pubmed	Tet family proteins and 5-hydroxymethylcytosine in development and disease.	TET2 TET1	1.37e-05	3	75	2	22569552
Pubmed	Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins.	TET2 TET1	1.37e-05	3	75	2	26356709
Pubmed	Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.	TET2 TET1	1.37e-05	3	75	2	29662175
Pubmed	A novel epigenetic marker, Ten-eleven translocation family member 2 (TET2), is identified in the intractable epileptic brain and regulates ATP binding cassette subfamily B member 1 (ABCB1) in the blood-brain barrier.	TET2 TET1	1.37e-05	3	75	2	35235761
Pubmed	One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering.	TET2 TET1	1.37e-05	3	75	2	23992847
Pubmed	Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.	TET2 TET1	1.37e-05	3	75	2	19372391
Pubmed	Inhibition of Tet1- and Tet2-mediated DNA demethylation promotes immunomodulation of periodontal ligament stem cells.	TET2 TET1	1.37e-05	3	75	2	31611558
Pubmed	The histone deacetylase SIRT6 controls embryonic stem cell fate via TET-mediated production of 5-hydroxymethylcytosine.	TET2 TET1	1.37e-05	3	75	2	25915124
Pubmed	Mechanisms of TET protein-mediated DNA demethylation and its role in the regulation of mouse development.	TET2 TET1	1.37e-05	3	75	2	25608811
Pubmed	Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.	TET2 TET1	1.37e-05	3	75	2	19420352
Pubmed	Overexpression of TET dioxygenases in seminomas associates with low levels of DNA methylation and hydroxymethylation.	TET2 TET1	1.37e-05	3	75	2	28218476
Pubmed	Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.	TET2 TET1	1.37e-05	3	75	2	23548903
Pubmed	MYC deregulates TET1 and TET2 expression to control global DNA (hydroxy)methylation and gene expression to maintain a neoplastic phenotype in T-ALL.	TET2 TET1	1.37e-05	3	75	2	31266538
Pubmed	5-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.	TET2 TET1	1.37e-05	3	75	2	34919053
Pubmed	Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells.	TET2 TET1	1.37e-05	3	75	2	24958354
Pubmed	No major role of common SV2A variation for predisposition or levetiracetam response in epilepsy.	SV2B SV2A	1.37e-05	3	75	2	18977120
Pubmed	One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering.	TET2 TET1	1.37e-05	3	75	2	23643243
Pubmed	Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation.	TET2 TET1	1.37e-05	3	75	2	34879277
Pubmed	Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.	TET2 TET1	1.37e-05	3	75	2	23352810
Pubmed	Oxygen regulation of TET enzymes.	TET2 TET1	1.37e-05	3	75	2	33410283
Pubmed	SV2 is the protein receptor for botulinum neurotoxin A.	SV2B SV2A	1.37e-05	3	75	2	16543415
Pubmed	Differential distribution and developmental expression of synaptic vesicle protein 2 isoforms in the mouse retina.	SV2B SV2A	1.37e-05	3	75	2	12687700
Pubmed	Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.	TET2 TET1	1.37e-05	3	75	2	21816367
Pubmed	Expression of SV2 isoforms during rodent brain development.	SV2B SV2A	1.37e-05	3	75	2	23937191
Pubmed	Effect of aging on 5-hydroxymethylcytosine in brain mitochondria.	TET2 TET1	1.37e-05	3	75	2	22445327
Pubmed	SV2 modulates the size of the readily releasable pool of secretory vesicles.	SV2B SV2A	1.37e-05	3	75	2	11483953
Pubmed	IGF2BP1 expression in human mesenchymal stem cells significantly affects their proliferation and is under the epigenetic control of TET1/2 demethylases.	TET2 TET1	1.37e-05	3	75	2	24915579
Pubmed	TET-catalyzed oxidation of intragenic 5-methylcytosine regulates CTCF-dependent alternative splicing.	TET2 TET1	1.37e-05	3	75	2	26711177
Pubmed	Overlapping functions of stonin 2 and SV2 in sorting of the calcium sensor synaptotagmin 1 to synaptic vesicles.	SV2B SV2A	1.37e-05	3	75	2	26015569
Pubmed	miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2.	TET2 TET1	1.37e-05	3	75	2	31941838
Pubmed	TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).	TET2 TET1	1.37e-05	3	75	2	12646957
Pubmed	Loss of Tet enzymes compromises proper differentiation of embryonic stem cells.	TET2 TET1	1.37e-05	3	75	2	24735881
Pubmed	PRDM14 promotes active DNA demethylation through the ten-eleven translocation (TET)-mediated base excision repair pathway in embryonic stem cells.	TET2 TET1	1.37e-05	3	75	2	24335252
Pubmed	Differential expression of ten-eleven translocation genes in endometrial cancers.	TET2 TET1	1.37e-05	3	75	2	28349832
Pubmed	Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns.	SV2B SV2A	1.37e-05	3	75	2	33588752
Pubmed	Zfp281 Coordinates Opposing Functions of Tet1 and Tet2 in Pluripotent States.	TET2 TET1	1.37e-05	3	75	2	27345836
Pubmed	Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.	TET2 TET1	1.37e-05	3	75	2	23453809
Pubmed	Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification.	TET2 TET1	1.37e-05	3	75	2	20639862
Pubmed	Ten-Eleven Translocation Genes are Downregulated in Endometriosis.	TET2 TET1	1.37e-05	3	75	2	26917261
Pubmed	Alternation of ten-eleven translocation 1, 2, and 3 expression in eutopic endometrium of women with endometriosis-associated infertility.	TET2 TET1	1.37e-05	3	75	2	30130982
Pubmed	Regulation of DNA methylation signatures on NF-κB and STAT3 pathway genes and TET activity in cigarette smoke extract-challenged cells/COPD exacerbation model in vitro.	TET2 TET1	1.37e-05	3	75	2	32342329
Pubmed	Tet-mediated DNA demethylation regulates specification of hematopoietic stem and progenitor cells during mammalian embryogenesis.	TET2 TET1	2.75e-05	4	75	2	35235365
Pubmed	[DNA hypomethylation in villi of patients with unexplained recurrent spontaneous abortion and its mechanism].	TET2 TET1	2.75e-05	4	75	2	31167695
Pubmed	Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine.	TET2 TET1	2.75e-05	4	75	2	21321204
Pubmed	Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.	TET2 TET1	2.75e-05	4	75	2	31371502
Pubmed	Loss of the SV2-like protein SVOP produces no apparent deficits in laboratory mice.	SV2B SV2A	2.75e-05	4	75	2	23894296
Pubmed	Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked β-N-acetylglucosamine transferase (OGT).	TET2 TET1	2.75e-05	4	75	2	24394411
Pubmed	Cotrafficking of SV2 and synaptotagmin at the synapse.	SV2B SV2A	2.75e-05	4	75	2	20410110
Pubmed	Activation-induced cytidine deaminase alters the subcellular localization of Tet family proteins.	TET2 TET1	2.75e-05	4	75	2	23028748
Pubmed	Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules.	TET2 TET1	2.75e-05	4	75	2	30554962
Pubmed	Spatial distribution and developmental appearance of postjunctional P2X1 receptors on smooth muscle cells of the mouse vas deferens.	SV2B SV2A	2.75e-05	4	75	2	11668586
Pubmed	Tet proteins connect the O-linked N-acetylglucosamine transferase Ogt to chromatin in embryonic stem cells.	TET2 TET1	2.75e-05	4	75	2	23352454
Pubmed	TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition.	TET2 TET1	2.75e-05	4	75	2	32234487
Pubmed	TET1 Directs Chondrogenic Differentiation by Regulating SOX9 Dependent Activation of Col2a1 and Acan In Vitro.	TET2 TET1	2.75e-05	4	75	2	33134768
Pubmed	UVB induces cutaneous squamous cell carcinoma progression by de novo ID4 methylation via methylation regulating enzymes.	TET2 TET1	2.75e-05	4	75	2	32574963
Coexpression	CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN	TGFB1I1 SV2A EPHA2 DOCK10 LHFPL6 LIX1L ADGRE5 EDIL3 ALKBH5	6.42e-06	465	74	9	M9192
Coexpression	GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_UP	MAG ARHGAP24 BTD NELFB ANKRD11 METTL8	6.89e-06	163	74	6	M6763
Coexpression	GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN	SELE ZHX3 HOXD9 TRO LHFPL6 STAB1	2.02e-05	197	74	6	M8165
Coexpression	MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN	ARHGAP24 TNFRSF18 TEX15 NOTCH3	3.92e-05	67	74	4	M9325
Coexpression	MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN	ARHGAP24 TNFRSF18 TEX15 NOTCH3	4.66e-05	70	74	4	MM809
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZHX3 SLC12A2 MAMDC2 ARFGEF1 DGKH CASZ1	4.73e-07	175	74	6	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ARHGAP24 MAMDC2 SCN4B TNFRSF13B EDIL3	7.06e-06	160	74	5	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ARHGAP24 MAMDC2 SCN4B TNFRSF13B EDIL3	7.06e-06	160	74	5	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	lymphoid-T_cell-pro-T_cell\|T_cell / Lineage, cell class and subclass	ARHGAP24 DUSP8 SCN4B CCL3 CASZ1	7.06e-06	160	74	5	66fe86d2f37983761141e5bb3de127f0b4bb0951
ToppCell	droplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 LPXN NT5C2 TNFRSF13B SEMA4A	8.44e-06	166	74	5	de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LPXN CCL3 SEMA4A STAB1	1.03e-05	173	74	5	a664dbd7fb55b1c4309fa5f9425bc83924dac545
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAMDC2 TRO GPR135 LHFPL6 NOTCH3	1.06e-05	174	74	5	41eb0a214a8b4015a26311f77061c8147144f0e7
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 RCBTB1 CNTNAP4 STAB1	1.15e-05	177	74	5	8dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 RCBTB1 CNTNAP4 STAB1	1.15e-05	177	74	5	767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCell	E18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 RCBTB1 CNTNAP4 STAB1	1.15e-05	177	74	5	5ef2527e9b41e62f1724cdabaad9d8979266bb7d
ToppCell	E18.5-Endothelial-Endothelial_lymphatic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 RCBTB1 CNTNAP4 STAB1	1.15e-05	177	74	5	ae1d2fdd4f67f50c906b27ea084de058c6908aa2
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHA2 DUSP8 DGKH MUC5B CASZ1	1.22e-05	179	74	5	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	E15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGFB1I1 TRO ENTPD2 LHFPL6 NOTCH3	1.25e-05	180	74	5	38035cf2c6fbc443ea10ca7e942572715ed572da
ToppCell	tumor_Lymph_Node_/_Brain-Endothelial_cells\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	SELE CCM2L HOXD9 SV2B LHFPL6	1.32e-05	182	74	5	d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SV2B CNTNAP4 LMO7DN LHFPL6 EDIL3	1.35e-05	183	74	5	b5d041d0a3506c33de72bf14fa0443f4410fddf1
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE SLC12A2 HOXD9 LHFPL6 NOTCH3	1.43e-05	185	74	5	c4ef8d9f8b9769e887daac4efd9dc05738b28ae2
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE SLC12A2 HOXD9 LHFPL6 NOTCH3	1.43e-05	185	74	5	10ddf38d908525b4258f9d2da8be4c56ebc08ff4
ToppCell	Control-B_memory-0\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ARHGAP24 DUSP8 TNFRSF13B ADGRE5 METTL8	1.46e-05	186	74	5	80f6f25dbe3c5efe4bc350f5d2eb990c38aab338
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 MAMDC2 LHFPL6 EDIL3 NOTCH3	1.50e-05	187	74	5	b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 MAMDC2 LHFPL6 EDIL3 NOTCH3	1.50e-05	187	74	5	9fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCell	droplet-Liver-HEPATOCYTES-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP24 MAMDC2 LHFPL6 EDIL3 NOTCH3	1.50e-05	187	74	5	e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCell	droplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHA2 DUSP8 EDIL3 CASZ1 STAB1	1.54e-05	188	74	5	db0652f000d459493321b53239326706eace598c
ToppCell	Neuronal_cells-Schwann_cells\|World / Lineage and Cell class	MAG RAB33A SLC12A2 SV2A EDIL3	1.58e-05	189	74	5	371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCell	Neuronal_cells\|World / Lineage and Cell class	MAG RAB33A SLC12A2 SV2A EDIL3	1.58e-05	189	74	5	3948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCell	Control-Myeloid-transitional_Macro\|Control / Disease group,lineage and cell class （2021.01.30）	SV2B LHFPL6 CCL3 KEL STAB1	1.66e-05	191	74	5	3ed0b1ff628a165e3c92c2e493206015f57dccfe
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-Treg\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	RAB33A LPXN TNFRSF13B TNFRSF18 METTL8	1.70e-05	192	74	5	c550b49abd30234851e19f35ad5ab8aba44bd3b5
ToppCell	15-Trachea-Endothelial-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	SELE HOXB7 CCM2L HOXD9 STAB1	1.75e-05	193	74	5	6ea0444fc3dc156997129387184e6418947f4b12
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAMDC2 TRO DUSP8 LHFPL6 NOTCH3	1.75e-05	193	74	5	469a7f1c2ff7137cc5a064464456911f67f92e70
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAMDC2 TRO DUSP8 LHFPL6 NOTCH3	1.75e-05	193	74	5	323d1f3f4fbeb93ba857fc135d8aa0b897f98ac5
ToppCell	15-Trachea-Endothelial\|Trachea / Age, Tissue, Lineage and Cell class	SELE HOXB7 CCM2L HOXD9 STAB1	1.75e-05	193	74	5	b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAG SLC12A2 CNTNAP4 KEL EDIL3	1.75e-05	193	74	5	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	Control-B_memory-0\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ARHGAP24 DUSP8 TNFRSF13B ADGRE5 METTL8	1.75e-05	193	74	5	b8d64cc0abc4a3311e172e7e48a7de0f2188effb
ToppCell	(7)_MNP-(7)_Macrophage\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	MAG ARHGAP24 TNFRSF13B KEL NOTCH3	1.88e-05	196	74	5	71ec157163278ad259c190051926bf41e4ecef46
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TGFB1I1 SCN4B LHFPL6 EDIL3 NOTCH3	1.88e-05	196	74	5	5146976881d79642ebe5dcbcf89e0252713a9ef2
ToppCell	COVID-19-lung-Pericytes/_Smooth_Muscle\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TGFB1I1 LHFPL6 DGKH EDIL3 NOTCH3	1.88e-05	196	74	5	754a3613340932563cd8424d775e18b93c3a1aaa
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TGFB1I1 SCN4B LHFPL6 EDIL3 NOTCH3	1.88e-05	196	74	5	ebac1d6af7a5732707d82d01285c086b19d8ae62
ToppCell	Bronchial_Brush-Epithelial-Basal_1\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	SV2A TET1 LHFPL6 SEMA4A EDIL3	1.93e-05	197	74	5	f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TGFB1I1 ARHGAP24 DOCK10 LHFPL6 NOTCH3	1.98e-05	198	74	5	72aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCell	Bronchial_Brush-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	SV2A TET1 LHFPL6 SEMA4A EDIL3	1.98e-05	198	74	5	10a17d7c116dcd6cf847fe6f5d7196d887cad1f9
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG SLC12A2 RCBTB1 DOCK10 EDIL3	2.02e-05	199	74	5	67d8c7e5356f5d409d4f98e8338cf6c499fd7aee
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAG SLC12A2 DOCK10 CNTNAP4 EDIL3	2.07e-05	200	74	5	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD56bright\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAG DOCK10 CCL3 TNFRSF18 CHRNB2	2.07e-05	200	74	5	1db27223e307efca97502fca40ec5e4f8eea512b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 RCBTB1 DOCK10 ANKRD11 EDIL3	2.07e-05	200	74	5	fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAG SLC12A2 DOCK10 CNTNAP4 EDIL3	2.07e-05	200	74	5	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAG SLC12A2 DOCK10 CNTNAP4 EDIL3	2.07e-05	200	74	5	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAG SLC12A2 DOCK10 CNTNAP4 EDIL3	2.07e-05	200	74	5	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG SLC12A2 RCBTB1 DOCK10 EDIL3	2.07e-05	200	74	5	e5b4821fff40566c4a7dc3f74a14e27eb06b165d
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAG SLC12A2 DOCK10 CNTNAP4 EDIL3	2.07e-05	200	74	5	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	MAG SLC12A2 DOCK10 CNTNAP4 EDIL3	2.07e-05	200	74	5	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_1\|367C / Donor, Lineage, Cell class and subclass (all cells)	RAB33A TNFRSF13B TNFRSF18 METTL8	1.05e-04	147	74	4	47544227faf9b0f107bcf6be92b5f423b50c8e92
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	RAB33A ARHGAP24 ZNF425 TNFRSF13B	1.05e-04	147	74	4	50a855aa7f214c3be8ac46a22adf9bc9dd0285db
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPXN LIX1L CCL3 TNFRSF18	1.14e-04	150	74	4	a3a4710820a244116a26204f40e7113a1e7236c5
ToppCell	facs-Marrow-Granulocytes-24m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPXN LIX1L CCL3 TNFRSF18	1.14e-04	150	74	4	13dcd519dacf08d5852aa3e029e0a3308de07321
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TGFB1I1 MAMDC2 EPHA2 NOTCH3	1.17e-04	151	74	4	527059e47e381b2f6d63c1abb39bc0795ee3829d
ToppCell	Frontal_cortex-Endothelial-MURAL\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TGFB1I1 MAMDC2 EPHA2 NOTCH3	1.17e-04	151	74	4	7570372a315bc312ff57bb5f483375c401ae8787
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TET1 ZFP28 RCBTB2 TNFRSF18	1.26e-04	154	74	4	d2aa24c593a1c0c6f186b74a18438b64b4e59701
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	TNFRSF13B TNFRSF18 METTL8 EDIL3	1.26e-04	154	74	4	9200e2f1783e54cbc5dfc3b485b57c761af74a46
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TNFRSF13B TNFRSF18 METTL8 EDIL3	1.26e-04	154	74	4	b16f3139ce50e70a6a2377b1da7d7877b4000ea1
ToppCell	E12.5-Hematopoietic\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LPXN TNFRSF13B KEL STAB1	1.36e-04	157	74	4	344351c7534440532c6cd4a95782ac90b10d45f3
ToppCell	LPS-antiTNF-Endothelial-Mes-Like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE HOXB7 SCN4B LIX1L	1.39e-04	158	74	4	50df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCell	NS-critical-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TGFB1I1 TRO LHFPL6 STAB1	1.46e-04	160	74	4	c61869d9dbba250270e59366e15af204e5b4395d
ToppCell	Club_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	ZNF716 MUC5B CHRNB2 NOTCH3	1.50e-04	161	74	4	bd08a23b415617f6e8748ed2668d578a860ecf91
ToppCell	Immune_cells-NK_cells\|World / Lineage and Cell class	CCL3 TNFRSF18 ADGRE5 SEMA4A	1.50e-04	161	74	4	3ef2e15b06286d94c18b71626aed456f681cc77b
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	DOCK10 DGKH EDIL3 NOTCH3	1.50e-04	161	74	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	droplet-Bladder-nan-3m-Hematologic-macrophage\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG LPXN CCL3 STAB1	1.53e-04	162	74	4	0cee9ef405765f3f82d0cd7b8adc88f6e9fdbb5c
ToppCell	droplet-Lung-nan-3m-Lymphocytic-NK_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG CCL3 TNFRSF18 SEMA4A	1.53e-04	162	74	4	4b490989005bb03d4e7bbea01580f8548eff150f
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Natural_Killer\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG CCL3 TNFRSF18 SEMA4A	1.53e-04	162	74	4	e4a09bf1a51710f6c57e6e01edf8b4619459d96d
ToppCell	Influenza_Severe-cDC\|World / Disease group and Cell class	EPHA2 LHFPL6 KEL CALHM3	1.61e-04	164	74	4	c984228f73b9aa1aaf948541f64f41ed874770cd
ToppCell	-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	RAB33A MAMDC2 TNFRSF13B TNFRSF18	1.61e-04	164	74	4	2d65f025f921a5327bfd8d260815baaed00ef3fa
ToppCell	T_cells-TFH-like_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	LHFPL6 TNFRSF18 DGKH METTL8	1.61e-04	164	74	4	b10cf59f4cc37ca6cd0ecf71d7de278cc2bdd8b5
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELE HOXB7 SCN4B LIX1L	1.68e-04	166	74	4	3b750d4023a0a09d86113aae5a97d84391f7b482
ToppCell	droplet-Limb_Muscle-nan-3m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LPXN CCL3 SEMA4A	1.68e-04	166	74	4	cd22d4222bc748942ed570a8978cb015e3b55388
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB33A ARHGAP24 CNTNAP4 TNFRSF13B	1.68e-04	166	74	4	a8ba4d51e778634f8a7f47fa0d01a2019f774fb8
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_B-B_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB33A ARHGAP24 CNTNAP4 TNFRSF13B	1.68e-04	166	74	4	4906c85f52c3751166e296102d524a13b1f438f5
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells-B_cells_L.1.5.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAB33A ARHGAP24 CNTNAP4 TNFRSF13B	1.68e-04	166	74	4	04e32bd32165cdf316f2a8709c3662d55cd70391
ToppCell	droplet-Limb_Muscle-nan-3m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LPXN CCL3 SEMA4A	1.68e-04	166	74	4	5f6031420bffb1813fe4989021f9f3a54a7243b0
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RASGRP4 DUSP8 ADGRE5 STAB1	1.72e-04	167	74	4	1cd9e2af85c6c5b9e1d88991c87ac6980b387243
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 GPR135 STAB1	1.72e-04	167	74	4	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	droplet-Limb_Muscle-nan-3m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LPXN CCL3 SEMA4A	1.72e-04	167	74	4	e984278c209cc52dbb752686db772e713afab33d
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 GPR135 STAB1	1.72e-04	167	74	4	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 GPR135 STAB1	1.72e-04	167	74	4	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	facs-MAT-Fat-18m-Myeloid-macrophage\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG RASGRP4 DOCK10 SEMA4A	1.72e-04	167	74	4	c2952d8ba763374c5678b92825c8956fc3e3ecd2
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCM2L HOXD9 GPR135 STAB1	1.72e-04	167	74	4	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	Posterior_cortex-Endothelial-MURAL\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TGFB1I1 MAMDC2 EPHA2 NOTCH3	1.80e-04	169	74	4	0ae65daf092396b71f790b65c7a2feed90397417
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD8-Trm/em_CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CCM2L ADGRE5 SEMA4A CASZ1	1.80e-04	169	74	4	17568e7aacfdcd96c469bae57d5ffad04954e9bd
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TGFB1I1 MAMDC2 EPHA2 NOTCH3	1.80e-04	169	74	4	8cd70ce27b1cecb83f8a376230e7ef41b079b124
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	LPXN CCL3 SEMA4A STAB1	1.84e-04	170	74	4	9ac1ef57f14418a5dd2aa16861c3df698c28f5ed
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RAB33A SV2A TNFRSF13B TNFRSF18	1.84e-04	170	74	4	aeac9de12efc727313946a77823aba8ab7cdfbfb
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRP4 SV2B LPXN DOCK10	1.84e-04	170	74	4	138235227fc4c3d660c3a06e8e5167bf64f076b3
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ARHGAP24 DOCK10 DGKH NOTCH3	1.84e-04	170	74	4	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FKTN DOCK10 ZFP28 TNFRSF18	1.84e-04	170	74	4	3ad9f950b87ee98f025ab9b4a8ed551e6a9b4764
ToppCell	BAL-Mild-Lymphocyte-T/NK-CD4+_T-Treg-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RAB33A SV2A TNFRSF13B TNFRSF18	1.84e-04	170	74	4	9a21048b0248a0cae00ec2d71d5056a678495385
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MAG LPXN NT5C2 STAB1	1.88e-04	171	74	4	bf475a69db04d4a886e442704955c6a96ff0de46
ToppCell	facs-Trachea-nan-18m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 LPXN TNFRSF13B CCL3	1.88e-04	171	74	4	9d496a6edac9663791cda684188d49895246f6fe
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	DOCK10 DGKH EDIL3 NOTCH3	1.88e-04	171	74	4	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	RASGRP4 SV2A DOCK10 STAB1	1.93e-04	172	74	4	c477008444d2d71071177807870d7455e90c2fad
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TGFB1I1 MAMDC2 LHFPL6 NOTCH3	1.97e-04	173	74	4	51328a60ffaf34fa0f7df6084d348b5efc9917f5
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LPXN DOCK10 CCL3 SEMA4A	1.97e-04	173	74	4	20f7dfe7d92a3dbec9da9a1f3185aa10cb8f0a3c
ToppCell	Globus_pallidus-Endothelial-MURAL\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TGFB1I1 MAMDC2 LHFPL6 NOTCH3	1.97e-04	173	74	4	b77cd5dbda3a206922f20224f4e10a3bf712f7db
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 CCL3 SEMA4A STAB1	1.97e-04	173	74	4	054f64462b648ba6b4b28b48c716dc01b2ddd790
Disease	pulse pressure measurement	TET2 HOXB7 ZNF716 ARHGAP24 SLC12A2 TET1 LPXN NT5C2 ANKRD11 CASZ1 NOTCH3	3.19e-04	1392	68	11	EFO_0005763
Disease	peritonsillar abscess	TET2 TNFRSF13B	7.82e-04	18	68	2	EFO_0007429
Disease	monocyte count	SELE TET2 RASGRP4 RCBTB1 DOCK10 TNFRSF13B ADGRE5 SEMA4A CASZ1 CHRNB2	8.49e-04	1320	68	10	EFO_0005091
Disease	unipolar depression, memory performance, cognitive function measurement	TET1 TNFRSF13B	9.68e-04	20	68	2	EFO_0003761, EFO_0004874, EFO_0008354
Disease	mean arterial pressure	HOXB7 ARHGAP24 NT5C2 DOCK10 REXO1 CASZ1	1.02e-03	499	68	6	EFO_0006340
Disease	upper respiratory tract disorder	TET2 TNFRSF13B	1.90e-03	28	68	2	MONDO_0004867
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	ADGRE5 CHRNB2	1.90e-03	28	68	2	DOID:1094 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FSRSCVDEGFSSPCT	FAM234A	121	Q9H0X4
CSPSFFDRFSVASSG	ANKRD11	1756	Q6UB99
FFTNCPRYTSCETGF	NT5C2	171	P49902
AGFCQFSSSADCAVP	CASZ1	1546	Q86V15
FATFSSCFPGLCEGK	DUSP8	126	Q13202
CLSEFACNAAFPDTS	ARFGEF1	1326	Q9Y6D6
VSVSFFSDSALCFGC	ALKBH5	216	Q6P6C2
GKCFVCAFSSSVDPE	CALHM3	121	Q86XJ0
ACRCNPGFSSFSEII	ADGRE5	41	P48960
CTFSAYTGPFCSNEI	CNTNAP4	986	Q9C0A0
PGECFCRSCFVTSSE	LINC00313	21	P59037
DFSCCSSFNGSQDTF	CCM2L	371	Q9NUG4
CTRFCGTSFFTVGDD	DCAF13	116	Q9NV06
RAFCSGCLSFSAAVP	ZFYVE19	101	Q96K21
SSHFSTPCFCRAFGQ	MUC5B	4936	Q9HC84
FSCTDDVFACFATPA	RCBTB1	326	Q8NDN9
SCTDDVFACFATPAV	RCBTB2	351	O95199
CLTFRFCGGTFPDKT	RAB33A	51	Q14088
FSASPRFCCQFITSV	INTS15	171	Q96N11
LPAGSCAFEESTCGF	MAMDC2	21	Q7Z304
AAQDFFSTCRSPEAC	UROD	51	P06132
SAFEGTCVSIPCRFD	MAG	31	P20916
SCSFSESDFPGCRDQ	LMO7DN	16	F2Z398
GLFSFSSCPFSRCSF	ENTPD2	316	Q9Y5L3
SSCPFSRCSFNGVFQ	ENTPD2	321	Q9Y5L3
FTSFDLFPEGSVCSD	FAM199X	106	Q6PEV8
TTDFPSFFCTLDNIC	PCYOX1L	361	Q8NBM8
TCFSPASDGSDFTFL	PCDHGC5	776	Q9Y5F6
VTFRKPTFCDSCSGF	RASGRP4	546	Q8TDF6
DRVNGFSCTCPSGFS	NOTCH3	486	Q9UM47
FCSSLFDGFFLTASP	NELFB	481	Q8WX92
SCFGSFQFCPTKAEA	LIX1L	146	Q8IVB5
PAGEFTFKSSCNFTC	SELE	321	P16581
AEFASCSFAPRSAVF	HOXD9	61	P28356
PECFVCGDCFTSFST	LPXN	291	O60711
CGDCFTSFSTGSFFE	LPXN	296	O60711
TDSDGFCRATFSFCV	DGKH	316	Q86XP1
SFLCAATSCVGFFMP	LHFPL6	16	Q9Y693
FATGAFPEQTSCAFA	HOXB7	21	P09629
CRSSTTTCPEQDFFG	ARHGAP24	571	Q8N264
LADGSFSCECPDGFT	EDIL3	41	O43854
PECFGTTDTTFSSAF	ICE1	1061	Q9Y2F5
RGFCAASRFFSSCFG	GPR135	181	Q8IZ08
SAFFQGPADLCGSFC	DOCK10	1551	Q96BY6
CSPGFFKFEASESPC	EPHA2	276	P29317
NPLSISCFFCGRFSI	C19orf67	191	A6NJJ6
TFDTPFAGRFGIFTC	BTD	231	P43251
FSASLAADTPTACCF	CCL3	21	P10147
GSTSQCKFFCVPRDF	FKTN	96	O75072
SPESFLYCCDFASGA	METTL8	221	Q9H825
SRCFELNTFSFCGNP	PRAMEF26	281	H0Y7S4
CQCPSTFYGSSCEFA	MUC3B	911	Q9H195
CDPFGSCDARFSDSE	REXO1	276	Q8N1G1
SAVCCFFLFFGNSES	SV2B	576	Q7L1I2
LPCTFSSCFGFEDLH	SCN4B	51	Q8IWT1
TCGTFAFSPACTFIE	SEMA4A	141	Q9H3S1
CVSCFFLSFGNSESA	SV2A	636	Q7L0J3
IDPETCGASFSFGCS	TET1	1566	Q8NFU7
LFFREAPGADSCTCF	CHRNB2	376	P17787
PFECAECGKSFSISS	ZFP28	616	Q8NHY6
PFECSECGRAFSSNR	ZNF197	761	O14709
SACFSGATSPSFCDG	TRO	1176	Q12816
NFDFSSCESSPCSYG	SLC12A2	571	P55011
TCEECGKAFSLPSTF	ZNF716	381	A6NP11
SNASAGCFAFCSPFS	STAB1	311	Q9NY15
GCFAFCSPFSCDRSA	STAB1	316	Q9NY15
FSDYVGSPITCTCFS	WDR83	186	Q9BRX9
FSFGFQCIDCASGTF	TNFRSF18	106	Q9Y5U5
SFCFPECRAPTQESA	TNFRSF13B	231	O14836
VCRECFAPFSGGSFF	TGFB1I1	371	O43294
SDCFDFSLSVPFTCG	TEX15	1801	Q9BXT5
LDPETCGASFSFGCS	TET2	1276	Q6N021
DPTFVCSGCSFLAKT	ZHX3	106	Q9H4I2
PFSCDECGRSFTYVG	ZNF425	721	Q6IV72
CGNVSVTFDPFCYLS	USP11	471	P51784
AVSPCGRFVASCGFT	TBL2	236	Q9Y4P3
SVAPCTDFFSFACGR	KEL	96	P23276
SGERPFACAECGQSF	MZF1	536	P28698