Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 GPR32P1 OR4C16 OR4A47 MC5R OR5B21 OR10H4 OR14I1 GRIK3 GPR183 VN1R1 ADCYAP1R1 OR51E2 OR10H3 OR4C46 ADGRF5 CCR7 OR5AP2	1.43e-08	884	131	23	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	NPC1 PLXNA3 GABRR2 OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 GPR32P1 OR4C16 OR4A47 MC5R OR5B21 OR10H4 OR14I1 GRIK3 GPR183 VN1R1 ADCYAP1R1 OR51E2 OR10H3 OR4C46 ADGRF5 CCR7 PLXNB1 OR5AP2	1.68e-07	1353	131	27	GO:0004888
GeneOntologyMolecularFunction	olfactory receptor activity	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 OR10H3 OR4C46 OR5AP2	9.51e-07	431	131	14	GO:0004984
GeneOntologyMolecularFunction	odorant binding	OR8I2 OR8H3 OR8D2 OR8B4 OR5B21 OR14I1 OR5AP2	2.07e-05	127	131	7	GO:0005549
GeneOntologyMolecularFunction	N-formyl peptide receptor activity	GPR32 GPR32P1	4.22e-04	5	131	2	GO:0004982
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 CALHM3 VN1R1 OR51E2 OR10H3 OR4C46 OR5AP2	4.00e-07	547	131	16	GO:0007606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 GPR32P1 OR4C16 OR4A47 AZU1 MC5R OR5B21 OR10H4 OR14I1 GRIK3 GPR183 VN1R1 ADCYAP1R1 OR51E2 OR10H3 KCTD16 OR4C46 ADGRF5 CCR7 TRPM1 OR5AP2	5.92e-07	1395	131	26	GO:0007186
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 OR10H3 OR4C46 OR5AP2	6.68e-07	432	131	14	GO:0050911
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 EXTL3 OR51E2 OR10H3 OR4C46 OR5AP2	1.24e-06	524	131	15	GO:0009593
GeneOntologyBiologicalProcess	sensory perception of smell	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 OR10H3 OR4C46 OR5AP2	1.59e-06	465	131	14	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 OR10H3 OR4C46 OR5AP2	2.60e-06	485	131	14	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 PGLYRP3 EXTL3 OR51E2 OR10H3 OR4C46 OR5AP2	1.41e-05	722	131	16	GO:0051606
GeneOntologyBiologicalProcess	lipid biosynthetic process	SPTLC3 PIGG ACSL1 ACSM4 KLHL25 MALRD1 PNPLA1 SYNJ1 CLN3 A4GALT INSIG2 ADGRF5 PRMT3 G6PD LIPI ALOX15 IP6K2	1.58e-05	813	131	17	GO:0008610
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 OR10H3 OR4C46 OR5AP2	2.05e-05	582	131	14	GO:0050906
GeneOntologyBiologicalProcess	sensory perception	CFH GABRR2 OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 CALHM3 VN1R1 OR51E2 OR10H3 OR4C46 TRPM1 OR5AP2	4.74e-05	1072	131	19	GO:0007600
GeneOntologyBiologicalProcess	organic hydroxy compound biosynthetic process	SPTLC3 ADCYAP1R1 MALRD1 INSIG2 APPL1 GATD1 G6PD ALOX15 IP6K2	7.07e-05	277	131	9	GO:1901617
Domain	GPCR_Rhodpsn_7TM	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 OR4C16 OR4A47 MC5R OR5B21 OR10H4 OR14I1 GPR183 VN1R1 OR51E2 OR10H3 OR4C46 CCR7 OR5AP2	1.52e-07	670	128	19	IPR017452
Domain	G_PROTEIN_RECEP_F1_1	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 OR4C16 OR4A47 MC5R OR5B21 OR10H4 OR14I1 GPR183 VN1R1 OR51E2 OR10H3 OR4C46 CCR7 OR5AP2	2.14e-07	685	128	19	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 OR4C16 OR4A47 MC5R OR5B21 OR10H4 OR14I1 GPR183 VN1R1 OR51E2 OR10H3 OR4C46 CCR7 OR5AP2	2.45e-07	691	128	19	PS50262
Domain	GPCR_Rhodpsn	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 OR4C16 OR4A47 MC5R OR5B21 OR10H4 OR14I1 GPR183 VN1R1 OR51E2 OR10H3 OR4C46 CCR7 OR5AP2	2.50e-07	692	128	19	IPR000276
Domain	Olfact_rcpt	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 OR10H3 OR4C46 OR5AP2	5.23e-07	393	128	14	IPR000725
Domain	7tm_1	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 GPR32 OR4C16 OR4A47 MC5R OR5B21 OR10H4 OR14I1 GPR183 OR51E2 OR10H3 OR4C46 CCR7 OR5AP2	8.51e-07	677	128	18	PF00001
Domain	Glyco_transf_64	EXT1 EXTL3	4.60e-04	5	128	2	PF09258
Domain	Exostosin	EXT1 EXTL3	4.60e-04	5	128	2	PF03016
Domain	Exostosin	EXT1 EXTL3	4.60e-04	5	128	2	IPR004263
Domain	EXT_C	EXT1 EXTL3	4.60e-04	5	128	2	IPR015338
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 CLCA1 OR10H3 OR4C46 OR5AP2	8.16e-08	389	99	15	M14091
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 OR51E2 OR10H3 OR4C46 OR5AP2	1.21e-06	417	99	14	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR14I1 CALHM3 OR51E2 OR10H3 OR4C46 OR5AP2	3.52e-05	636	99	15	M41834
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR51E2 OR10H3 OR4C46 OR5AP2	8.11e-10	340	134	13	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR51E2 OR10H3 OR4C46 OR5AP2	8.11e-10	340	134	13	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR51E2 OR10H3 OR4C46 OR5AP2	9.02e-10	343	134	13	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR5B21 OR10H4 OR51E2 OR10H3 OR4C46 OR5AP2	1.00e-09	346	134	13	14611657
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 PLXNA3 KIAA0319L HECTD4 SIAH2 PIGG EXTL3 PLEKHM1 ARSG FANCA FAT1 KLHL25 SYNJ1 XPO6 BTBD7 CLN3 A4GALT SIPA1L2 PRDM16	5.27e-08	1105	134	19	35748872
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	NPC1 CFH PLXNA3 FSTL3 KIAA0319L EXT1 PIGG EXTL3 ATP9A TMED4 DMXL1 FANCA FAT1 XPO6 A4GALT G6PD PLXNB1	3.97e-06	1201	134	17	35696571
Pubmed	Biosynthesis of heparan sulfate in EXT1-deficient cells.	EXT1 EXTL3	1.47e-05	2	134	2	20377530
Pubmed	Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways.	SIAH2 DYRK2	1.47e-05	2	134	2	22878263
Pubmed	Epstein-Barr virus-induced genes: first lymphocyte-specific G protein-coupled peptide receptors.	GPR183 CCR7	1.47e-05	2	134	2	8383238
Pubmed	Tissue and zonal-specific expression of an olfactory receptor transgene.	OR10H4 OR10H3	1.47e-05	2	134	2	9412503
Pubmed	EXTL3 and NPC1 are mammalian host factors for Autographa californica multiple nucleopolyhedrovirus infection.	NPC1 EXTL3	1.47e-05	2	134	2	39231976
Pubmed	Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis.	ZNF521 OR10H4 OR10H3	3.02e-05	16	134	3	17521568
Pubmed	Cloning genes encoding receptors related to chemoattractant receptors.	GPR32 GPR32P1	4.41e-05	3	134	2	9653656
Pubmed	EBI2 operates independently of but in cooperation with CXCR5 and CCR7 to direct B cell migration and organization in follicles and the germinal center.	GPR183 CCR7	4.41e-05	3	134	2	21948984
Pubmed	SIAH2 is Expressed in Adipocyte Precursor Cells and Interacts with EBF1 and ZFP521 to Promote Adipogenesis.	ZNF521 SIAH2	4.41e-05	3	134	2	33155406
Pubmed	Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1.	CFH TFCP2	4.41e-05	3	134	2	26723877
Pubmed	Shape and Function of Interstitial Chemokine CCL21 Gradients Are Independent of Heparan Sulfates Produced by Lymphatic Endothelium.	EXT1 CCR7	4.41e-05	3	134	2	33717158
Pubmed	The human olfactory receptor gene family.	OR8I2 OR8H3 OR8D2 OR8B4 OR11G2 OR4C16 OR4A47 OR10H4 OR51E2 OR10H3	4.97e-05	541	134	10	14983052
Pubmed	mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development.	DYRK3 DYRK2	8.80e-05	4	134	2	11159515
Pubmed	Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation.	EXT1 EXTL3	8.80e-05	4	134	2	17761672
Pubmed	Endothelial heparan sulfate controls chemokine presentation in recruitment of lymphocytes and dendritic cells to lymph nodes.	EXT1 CCR7	8.80e-05	4	134	2	21093315
Pubmed	Access to follicular dendritic cells is a pivotal step in murine chronic lymphocytic leukemia B-cell activation and proliferation.	GPR183 CCR7	8.80e-05	4	134	2	25252690
Pubmed	A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.	PLXNA3 PLXNB1	8.80e-05	4	134	2	8570614
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF13B ZNF407 ZBTB26 ARSG KCNS2 APPL1 ADGRF5 PRDM16 MAST3	1.31e-04	493	134	9	15368895
Pubmed	Reduced VLDL clearance in Apoe(-/-)Npc1(-/-) mice is associated with increased Pcsk9 and Idol expression and decreased hepatic LDL-receptor levels.	NPC1 MYLIP	1.46e-04	5	134	2	20562239
Pubmed	Structural analysis of the RZZ complex reveals common ancestry with multisubunit vesicle tethering machinery.	ZWILCH NBAS	1.46e-04	5	134	2	20462495
Pubmed	LIS1 regulates osteoclast formation and function through its interactions with dynein/dynactin and Plekhm1.	PLEKHM1 DYNC1I1	1.46e-04	5	134	2	22073305
Pubmed	The putative tumor suppressors EXT1 and EXT2 form a stable complex that accumulates in the Golgi apparatus and catalyzes the synthesis of heparan sulfate.	EXT1 EXTL3	1.46e-04	5	134	2	10639137
Pubmed	DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.	DYRK3 DYRK2	1.46e-04	5	134	2	20167603
Pubmed	Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis.	DYNC1I1 DYRK2	2.19e-04	6	134	2	31815665
Pubmed	Regulation of Rev1 by the Fanconi anemia core complex.	FANCA REV1	2.19e-04	6	134	2	22266823
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	TTC28 RALGAPB SYNJ1 XPO6 APPL1 PRDM16	2.47e-04	225	134	6	12168954
Pubmed	Maternal aldehyde elimination during pregnancy preserves the fetal genome.	FANCA REV1	3.06e-04	7	134	2	25155611
Pubmed	Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.	DYRK3 DYRK2	3.06e-04	7	134	2	9748265
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR8D2 OR8B4 OR4C16	3.34e-04	35	134	3	16939646
Pubmed	The expression of plexins during mouse embryogenesis.	PLXNA3 PLXNB1	4.06e-04	8	134	2	15661641
Pubmed	Personal receptor repertoires: olfaction as a model.	OR8D2 OR8B4 OR4C16	4.27e-04	38	134	3	22908908
Pubmed	Acsl1 is essential for skin barrier function through the activation of linoleic acid and biosynthesis of ω-O-acylceramide in mice.	ACSL1 PNPLA1	5.21e-04	9	134	2	34813948
Pubmed	The role of neuropilins in cell signalling.	PLXNA3 PLXNB1	5.21e-04	9	134	2	19909241
Pubmed	Characterization of lipid-linked oligosaccharide accumulation in mouse models of Batten disease.	NPC1 CLN3	5.21e-04	9	134	2	15647513
Pubmed	A comparative transcriptional map of a region of 250 kb on the human and mouse X chromosome between the G6PD and the FLN1 genes.	PLXNA3 G6PD	6.50e-04	10	134	2	7490070
Pubmed	Mapping of multiple mouse loci related to the farnesyl pyrophosphate synthetase gene.	HAL G6PD	6.50e-04	10	134	2	8499655
Pubmed	Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis.	PRDM16 ALOX15	6.50e-04	10	134	2	29539416
Pubmed	Characterization of a cluster comprising approximately 100 odorant receptor genes in mouse.	OR8D2 OR8B4	6.50e-04	10	134	2	11130974
Pubmed	Supersensitive detection and discrimination of enantiomers by dorsal olfactory receptors: evidence for hierarchical odour coding.	OR5B21 ACSM4	7.92e-04	11	134	2	26361056
Pubmed	The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.	SPTLC3 PNPLA1	7.92e-04	11	134	2	31578523
Pubmed	Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.	PLXNA3 PLXNB1	9.48e-04	12	134	2	21270798
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	PLXNA3 PLXNB1	1.12e-03	13	134	2	10520995
Pubmed	The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina.	CALB2 PRDM16	1.12e-03	13	134	2	29053761
Pubmed	Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci.	PLXNA3 G6PD	1.30e-03	14	134	2	8733135
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	PLXNA3 FSTL3 GRIK3 ATP9A FAT1 CLCA1 MAST3 REV1	1.39e-03	552	134	8	10737800
Pubmed	Comprehensive analysis of DNA repair gene variants and risk of meningioma.	FANCA EXO1 REV1	1.41e-03	57	134	3	18270339
Pubmed	Knockout Mice for Dyslexia Susceptibility Gene Homologs KIAA0319 and KIAA0319L have Unaffected Neuronal Migration but Display Abnormal Auditory Processing.	CALB2 KIAA0319L	1.50e-03	15	134	2	29045729
Pubmed	A genome-wide association study on obesity and obesity-related traits.	TTC28 FAT1	1.50e-03	15	134	2	21552555
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR8I2 OR8B4 OR11G2 OR4A47 OR10H4	1.64e-03	219	134	5	12213199
Pubmed	Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.	PLXNA3 PLXNB1	1.71e-03	16	134	2	17356169
Pubmed	Impaired cortical neurogenesis in plexin-B1 and -B2 double deletion mutant.	CALB2 PLXNB1	1.71e-03	16	134	2	26579598
Pubmed	Gene deletion mutants reveal a role for semaphorin receptors of the plexin-B family in mechanisms underlying corticogenesis.	CALB2 PLXNB1	1.71e-03	16	134	2	19948886
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DYNLT2B RIOK1 TTC28 KIAA0319L DPYSL5 KBTBD2 TFCP2 SYNJ1 SIPA1L2 DYNC1I1	1.78e-03	853	134	10	28718761
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	KIF13B DYNLT2B KIFBP RIOK1 EIF3E DPYSL5 TMED4 MKS1 ACSL1 XPO6 APPL1 MAST3 DYRK2	1.82e-03	1321	134	13	27173435
Pubmed	Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.	PLXNA3 PLXNB1	1.93e-03	17	134	2	11683995
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	PLXNA3 PLXNB1	1.93e-03	17	134	2	17626059
Pubmed	CRL7SMU1 E3 ligase complex-driven H2B ubiquitylation functions in sister chromatid cohesion by regulating SMC1 expression.	DYRK3 DYRK2	2.17e-03	18	134	2	29507117
Pubmed	PDGFRα controls the balance of stromal and adipogenic cells during adipose tissue organogenesis.	ZNF521 PRDM16	2.41e-03	19	134	2	28049691
Pubmed	Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo.	CALB2 PLXNB1	2.41e-03	19	134	2	17554007
Pubmed	mSYD1A, a mammalian synapse-defective-1 protein, regulates synaptogenic signaling and vesicle docking.	SYDE2 UNC13A	2.68e-03	20	134	2	23791195
Pubmed	Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.	KIAA0319L ATP9A APPL1	2.75e-03	72	134	3	34882091
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF19 NBPF15	2.95e-03	21	134	2	16079250
Pubmed	Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function.	PLXNA3 CALB2	2.95e-03	21	134	2	21835343
Pubmed	Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels.	MALRD1 KLB	2.95e-03	21	134	2	23747249
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR8D2 OR11G2 OR4C16	2.97e-03	74	134	3	15081110
Pubmed	Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.	TMEM176B SIAH2 GRIK3 ATP9A	3.18e-03	156	134	4	22008794
Pubmed	Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.	GABRR2 GRIK3 ADCYAP1R1	3.83e-03	81	134	3	22723691
Pubmed	Follistatin Targets Distinct Pathways To Promote Brown Adipocyte Characteristics in Brown and White Adipose Tissues.	ACSL1 PRDM16	3.85e-03	24	134	2	28324027
Pubmed	Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains.	INSIG2 G6PD	3.85e-03	24	134	2	15561968
Pubmed	A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.	PLXNA3 PLXNB1	3.85e-03	24	134	2	28893946
GeneFamily	Olfactory receptors, family 8	OR8I2 OR8H3 OR8D2 OR8B4	1.07e-04	49	91	4	155
GeneFamily	Exostosin glycosyltransferase family	EXT1 EXTL3	2.48e-04	5	91	2	431
GeneFamily	Plexins	PLXNA3 PLXNB1	8.82e-04	9	91	2	683
ToppCell	pdx-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	AOX1 KIAA0319L HECTD4 MYLIP PRDM16 PID1 KLB	1.50e-06	185	134	7	1d874608aa2062024323512f68889219471b2f00
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	ZWILCH KIFBP CASP2 EXTL3 FANCA SLC35G1 DYNC1I1	1.99e-06	193	134	7	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GPM6A TMEM176B CLCA1 MYLIP ADGRF5	1.46e-05	174	134	6	42dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCell	facs-Heart-RA-24m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GPM6A TMEM176B CLCA1 MYLIP ADGRF5	1.46e-05	174	134	6	f04edf2ca6788875c9918611e416fb739924382e
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NBAS ZNF17 HHAT ZNF816 INSIG2 CCR7	1.77e-05	180	134	6	9f4bbaf6435c23e3e552ae22be8ea7884314192d
ToppCell	BAL-Severe-Lymphocyte-B-B_cell-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NBAS ZNF17 HHAT ZNF816 INSIG2 CCR7	1.77e-05	180	134	6	b465f2f8b0e9a2034a4f1272bb00c77439164dbf
ToppCell	BAL-Severe-Lymphocyte-B-B_cell\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NBAS ZNF17 HHAT ZNF816 INSIG2 CCR7	1.77e-05	180	134	6	c3c72531af5b9f7a7416727fe609dab5180e03b6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6A GABRR2 ZNF521 TNFAIP8L1 ADGRF5 DNASE1L3	1.95e-05	183	134	6	dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6A GABRR2 ZNF521 TNFAIP8L1 ADGRF5 DNASE1L3	1.95e-05	183	134	6	4759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6A ZNF521 EXO1 ADGRF5 SIPA1L2 DNASE1L3	2.01e-05	184	134	6	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	LVRN CFH ADAMTSL1 TTC28 AOX1 PID1	2.07e-05	185	134	6	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GPM6A ADAMTSL1 KIAA0319L MALRD1 ADGRF5 PRDM16	2.55e-05	192	134	6	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	CFH TTC28 AOX1 ZNF521 EXT1 PID1	2.70e-05	194	134	6	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	CFH TTC28 AOX1 ZNF521 EXT1 PID1	2.78e-05	195	134	6	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	mild-Myeloid-Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	KIAA0319L DTX3L ADAR ACSL1 XPO6 SIPA1L2	2.86e-05	196	134	6	ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GPM6A ADAMTSL1 ZNF521 ADGRF5 SIPA1L2 DNASE1L3	2.86e-05	196	134	6	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	SPTLC3 AZU1 PIGG XPO6 SYDE2 DYRK3	3.20e-05	200	134	6	be83f442179ba4217d12f0458059586ff3130991
ToppCell	Endothelial-G\|World / shred on cell class and cell subclass (v4)	GPM6A ADAMTSL1 ZNF521 TNFAIP8L1 CLCA1	3.68e-05	124	134	5	4b72809463f2986b7d1b7ab9de633ac4d7854a92
Disease	myeloblastin measurement	CFH AZU1 PSMD3	1.54e-06	6	127	3	EFO_0020585
Disease	Down syndrome (implicated_via_orthology)	SYNJ1 DYRK3 DYRK2	3.41e-05	15	127	3	DOID:14250 (implicated_via_orthology)
Disease	ovulation	PLEKHM1 FANCA ACSL1	7.17e-05	19	127	3	GO_0030728
Disease	hereditary multiple exostoses (implicated_via_orthology)	EXT1 EXTL3	1.10e-04	4	127	2	DOID:206 (implicated_via_orthology)
Disease	Neuronal Ceroid-Lipofuscinoses	ARSG CLN3	2.73e-04	6	127	2	C0027877
Disease	osteocalcin measurement	CFH SPTLC3	3.81e-04	7	127	2	EFO_0010232
Disease	cysteine measurement	FMO4 GRIK3	6.49e-04	9	127	2	EFO_0021000
Disease	sunburn	ADAR FANCA TRPM1 HAL	8.01e-04	96	127	4	EFO_0003958
Disease	Fuchs endothelial corneal dystrophy	CFH GATD1	8.09e-04	10	127	2	Orphanet_98974
Disease	DNA repair protein RAD51 homolog 4 measurement	CFH TEX14	9.86e-04	11	127	2	EFO_0801531
Disease	Gastrointestinal Stromal Sarcoma	NPC1 HHAT DYRK2	1.10e-03	47	127	3	C3179349
Disease	oncostatin-M measurement	CFH PSMD3	1.18e-03	12	127	2	EFO_0010792
Disease	alcohol consumption measurement, alcohol drinking	HECTD4 KLB	1.18e-03	12	127	2	EFO_0004329, EFO_0007878
Disease	Gastrointestinal Stromal Tumors	NPC1 HHAT DYRK2	1.32e-03	50	127	3	C0238198
Disease	kynurenic acid measurement	ZNF177 DYRK2	1.39e-03	13	127	2	EFO_0010506
Disease	Antimigraine preparation use measurement	PRDM16 PID1	3.66e-03	21	127	2	EFO_0009939
Disease	breast cancer, COVID-19	TTC28 PLEKHM1	4.01e-03	22	127	2	MONDO_0007254, MONDO_0100096
Disease	complement factor H-like 1 protein measurement	CFH PID1	4.01e-03	22	127	2	EFO_0600092

Protein segments in the cluster

Peptide	Gene	Start	Entry
VESIYQAMTHFACLS	UNC13A	871	Q9UPW8
ACTSHKVRRAMFSAT	DDX52	341	Q9Y2R4
CDMVFRSSALLATHT	CCDC17	16	Q96LX7
NFLFMCSVESAARTH	A4GALT	91	Q9NPC4
AMVTHRNIVSDCSAF	ACSL1	286	P33121
RCVLHFFASMRSELQ	CALHM3	241	Q86XJ0
RMARTVSTVCFFHLA	GPR32	71	O75388
QAMRCSLITEHVEAF	CCR7	206	P32248
TAFHVTCAQRAGLFM	BRPF3	346	Q9ULD4
GMRFVDFHAAASTCS	ARSG	71	Q96EG1
CVFVHRMAQFDTDTF	ACSM4	291	P0C7M7
EFNCSESFTMIGHRS	CFH	716	P08603
RMLSCFLNEHLFVSA	LVRN	511	Q6Q4G3
SQDFVMHVSIFECES	DMXL1	1071	Q9Y485
IMTAEHLSDVNSFCF	AOX1	641	Q06278
ILDVFCGSQMHFVRS	G6PD	441	P11413
SMLRLTFCDSNVIDH	OR8B4	161	Q96RC9
AFSTCASHLMAVTIF	OR8I2	236	Q8N0Y5
FSILARCTQDDHEMV	FAT1	2776	Q14517
FFICITIQRMHSAEG	OR5B21	216	A6NL26
ATVHTTRMSVLSFCR	OR8D2	156	Q9GZM6
DTCTRMFIAALFTIA	nan	1191	O00370
SVDVRMIDFAHTTCR	IP6K2	376	Q9UHH9
HMVACNSSVTASFIN	KCTD16	246	Q68DU8
CRAFRTHSSNSMLVF	KIAA0319L	116	Q8IZA0
MCESTELNMTFHLFI	GPM6A	201	P51674
NIFRMTESHLLVTCD	APPL1	536	Q9UKG1
SAQVFEHLICMDSRD	CARF	21	Q8N187
VFHCQSSVMSVCFAR	DYNC1I1	336	O14576
SSVMSVCFARFHPNL	DYNC1I1	341	O14576
VFCSHLLSREMNETV	ADAMTSL1	691	Q8N6G6
VHMDTFQVARIAYCT	PID1	156	Q7Z2X4
VAQTFMDSCSTSEHR	PLXNA3	1751	P51805
VIAQTFMDACTLADH	PLXNB1	2011	O43157
STCSSHMTVVVFFFV	OR4A47	236	Q6IF82
ACTDTHMLELFIAAN	OR4C46	186	A6NHA9
CLTQMFFIHALSAIE	OR51E2	96	Q9H255
NIQSFHMDTRNFCDI	PGLYRP3	226	Q96LB9
NRAVFDAVMVCTGHF	FMO4	136	P31512
HVMAELCVFSFSQEI	KCNS2	91	Q9ULS6
SNSLCVFMRETHLNE	KBTBD2	531	Q8IY47
CSFQFSLENIARMTH	PNPLA1	216	Q8N8W4
ARDQVCHFVTMCIFT	ALOX15	521	P16050
THAFYRCDTVTSAVM	MYLIP	271	Q8WY64
QDIMRVCSESSTHFA	KRIT1	136	O00522
VIHRSLCISTMQAVF	ATP9A	846	O75110
VRACMFSSHLTSVTF	HECTD4	1951	Q9Y4D8
SSVMRCVAVFVGINH	INSIG2	106	Q9Y5U4
NAAIHTGMTFRLSFC	OR5AP2	161	Q8NGF4
LATRQELMAFALTHC	NBAS	1331	A2RRP1
LHCTRNFIHMNLFVS	ADCYAP1R1	181	P41586
SFVNVVSMSRLHFCD	OR8H3	156	Q8N146
RSITFVACAIQMFFS	OR10H3	91	O60404
HSITFVACANQMFFS	OR10H4	91	Q8NGA5
EFCSHITRAFTVSMK	NPC1	1166	O15118
MVLLHTTISFCVAQF	HHAT	116	Q5VTY9
MTHITVAVLCFLANR	MALRD1	2086	Q5VYJ5
EGVSAQSFLHCFTMA	GATD1	21	Q8NB37
FMIAHCTAAALVSEN	HAL	496	P42357
MCLVHFETVRQSEDF	KLHL25	171	Q9H0H3
HSALAMRICSFNVRS	DNASE1L3	16	Q13609
MLSHRCFNTLTNSFQ	ADAR	846	P55265
DHFAQRQSCMNTFAS	EXT1	696	Q16394
SFIDAFQHASCQLMR	DTX3L	436	Q8TDB6
QDFVMHTDVRTCSSS	PRMT3	191	O60678
VTYISSCHMRQATCF	FSTL3	216	O95633
RMARTVSTVCFFHLA	GPR32P1	71	Q8NGA4
CEDIAMNFLVSHITR	EXTL3	831	O43909
LAHSMFSRLSFCQEL	FANCA	156	O15360
FETFCRIHQCISINM	EIF3E	341	P60228
QALHFLCEEFSQVMT	BTBD7	421	Q9P203
FVVSMFCSFETRRHL	MAST3	426	O60307
VRHIDNVFDSMICIS	MC5R	111	P33032
CALNHFTTRFVMHEQ	KLB	821	Q86Z14
ECSLSMRSVAHAAIF	KNDC1	61	Q76NI1
MRSVAHAAIFQSLCI	KNDC1	66	Q76NI1
CFRQHVGSSAEFMEA	CALB2	101	P22676
EFRIIFDCSHTMAAQ	GRIK3	226	Q13003
LIHARFVMTAASCFQ	AZU1	56	P20160
KSTFIREFFCSMHTV	CFAP47	2061	Q6ZTR5
FTFRNHICMTFELLS	DYRK2	291	Q92630
CAFIDSPEFRSTQMH	BVES	196	Q8NE79
AQVFSERACDMHVAD	CASP2	391	P42575
VIHMLESFTFRNHVC	DYRK3	271	O43781
ESFTFRNHVCMAFEL	DYRK3	276	O43781
THDVFMNDSLFCVVA	DYNLT2B	121	Q8WW35
FMEARHCLSAANVIF	KIFBP	266	Q96EK5
STHFHQTFMNATCVD	DPYSL5	66	Q9BPU6
RITVTAMCNMDFSHF	GABRR2	171	P28476
ISQMSFCGSRIIDHF	OR11G2	201	Q8NGC1
SFSECMIQVFSSHVF	OR4C16	91	Q8NGL9
MFREHVCRSSVIHQF	OR14I1	161	A6ND48
CRSMDRFSFHSPSAQ	KIF13B	651	Q9NQT8
MVVFDHCNEFSVNIT	KIF13B	921	Q9NQT8
DANTMCSALEAVFIH	PLEKHM1	46	Q9Y4G2
CANVNDFFMRHSVAV	RIOK1	361	Q9BRS2
CRTTFLDMDHTFNIE	SYDE2	721	Q5VT97
RSTQIVEFMQRCASH	TEX14	136	Q8IWB6
AVAIRMLFHTTSLCF	SYNJ1	671	O43426
AVHLFMASLETNCNF	LIPI	256	Q6XZB0
SSTFHSLEEQQVCMA	NBPF15	311	Q8N660
SSTFHSLEEQQVCMA	NBPF19	311	A0A087WUL8
MSLVCLTDFQAHARE	HAO2	1	Q9NYQ3
MFSTTSSLNKHRRFC	PRDM16	431	Q9HAZ2
FMTCLSIDRFIAVVH	GPR183	121	P32249
DQRVASFCTLTDMQH	SIPA1L2	1606	Q9P2F8
IMNSDCLVFDTAIAH	SIAH2	291	O43255
RFCVSAAHTREMLDT	SPTLC3	501	Q9NUV7
LMTCFQEADAVTHSD	REELD1	106	A0A1B0GV85
RECFTRSINITHAMA	EXO1	116	Q9UQ84
FATAMAAVVLCVNSF	TMEM176B	136	Q3YBM2
TSYMRHTCIVNIAAS	ADGRF5	1046	Q8IZF2
SDEHREFAMAATCIS	CLN3	401	Q13286
SIMFAQHVDSIVEFC	CLCA1	236	A8K7I4
CHVSSTDMLQTIRQF	RIN2	546	Q8WYP3
RIFFTNMVTCSQVHF	ZWILCH	576	Q9H900
FCLNSSFTQHMRIHT	ZNF599	376	Q96NL3
MSFSLHSSCSVREQI	ZNF177	211	Q13360
FHQRISFCLDIHNMS	PSMD3	476	O43242
VTFRLHCLQQSRAFM	MKS1	486	Q9NXB0
HCLQQSRAFMESSSL	MKS1	491	Q9NXB0
HVDMDCFFVSVGIRN	REV1	421	Q9UBZ9
FIQVHCISTEFTMRK	TFCP2	186	Q12800
MHTFVFFRCTLCQEV	ZNF521	716	Q96K83
ELFTCVSEQFTAMFR	TUBB8B	376	A6NNZ2
IMSDTHISQFCFACR	VN1R1	326	Q9GZP7
SRDLHSMIVAAFQCL	RALGAPB	826	Q86X10
RDFIAHTCSQMLLTD	TRPM1	721	Q7Z4N2
QICLHSNSTRMALFA	TMED4	111	Q7Z7H5
ERVMSALTQAECVHF	TTC28	1531	Q96AY4
CTEQTLFRMHNGFSI	TTC12	276	Q9H892
HAVEISAFRCVFQML	SLC35G1	96	Q2M3R5
CRSSNSMAFLAHIRT	ZNF407	1546	Q9C0G0
LESLMTEFFHDCTTN	XPO6	11	Q96QU8
AAVCVFFTAMDQTRL	PIGG	966	Q5H8A4
CLAMTAVSFHQVDFT	TNFAIP8L1	96	Q8WVP5
FFMDSCTLIIHQRVH	ZNF17	366	P17021
FRCIFSLAMSSHFTQ	ZNF195	141	O14628
AASFLQMSHIVERCT	ZBTB26	106	Q9HCK0
FLHSSFTQIQEICMR	ZNF816	211	Q0VGE8
SALFQHITALFECSM	JKAMP	86	Q9P055