Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesslymphocyte chemotaxis

SLC12A2 PIK3CG CYP7B1 WNK1

2.49e-0553664GO:0048247
DomainABC_A

ABCA6 ABCA9 ABCA8

8.65e-0612653IPR026082
DomainABC_tran

ABCA6 ABCA9 ABCA8

6.22e-0448653PF00005
DomainABC_TRANSPORTER_2

ABCA6 ABCA9 ABCA8

6.22e-0448653PS50893
DomainABC_TRANSPORTER_1

ABCA6 ABCA9 ABCA8

6.61e-0449653PS00211
DomainABC_transporter-like

ABCA6 ABCA9 ABCA8

7.02e-0450653IPR003439
DomainRoc

LRRK1 AGAP2

9.08e-0413652PF08477
DomainMIRO-like

LRRK1 AGAP2

9.08e-0413652IPR013684
DomainAAA+_ATPase

ABCA6 ABCA9 ABCA8 DNAH11

1.59e-03144654IPR003593
DomainAAA

ABCA6 ABCA9 ABCA8 DNAH11

1.59e-03144654SM00382
DomainP-loop_NTPase

ABCA6 MYO9A WRN ERCC6L2 LRRK1 ABCA9 ABCA8 AGAP2 DNAH11

2.56e-03848659IPR027417
DomainIQ

RASGRF2 MYO9A SCN7A

2.83e-0381653SM00015
DomainIQ_motif_EF-hand-BS

RASGRF2 MYO9A SCN7A

3.81e-0390653IPR000048
Domain-

ABCA6 WRN ERCC6L2 LRRK1 ABCA9 ABCA8 AGAP2 DNAH11

4.22e-037466583.40.50.300
DomainArfGap

ASAP2 AGAP2

4.56e-0329652SM00105
DomainArfGap

ASAP2 AGAP2

4.56e-0329652PF01412
DomainARFGAP

ASAP2 AGAP2

4.56e-0329652PS50115
DomainArfGAP

ASAP2 AGAP2

4.56e-0329652IPR001164
DomainDEAH_ATP_HELICASE

WRN ERCC6L2

7.73e-0338652PS00690
Pubmed

Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.

ABCA6 ABCA9 ABCA8

6.51e-08566312532264
Pubmed

Novel recurrently mutated genes in African American colon cancers.

EPHA6 FLCN

3.55e-06266225583493
Pubmed

Novel nuclear shuttle proteins, HDBP1 and HDBP2, bind to neuronal cell-specific cis-regulatory element in the promoter for the human Huntington's disease gene.

SLC2A4RG ZNF395

3.55e-06266214625278
Pubmed

With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl- cotransporters.

SLC12A2 WNK1

3.55e-06266227170636
Pubmed

Regulation of erythrocyte Na+/K+/2Cl- cotransport by an oxygen-switched kinase cascade.

SLC12A2 WNK1

1.06e-05366230563844
Pubmed

WNK1-OSR1 kinase-mediated phospho-activation of Na+-K+-2Cl- cotransporter facilitates glioma migration.

SLC12A2 WNK1

2.12e-05466224555568
Pubmed

Acute digoxin loading reduces ABCA8A mRNA expression in the mouse liver.

ABCA9 ABCA8

2.12e-05466216445568
Pubmed

Structural insights into the recognition of substrates and activators by the OSR1 kinase.

SLC12A2 WNK1

2.12e-05466217721439
Pubmed

Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.

SLC12A2 WNK1

2.12e-05466231615901
Pubmed

Interactions with WNK (with no lysine) family members regulate oxidative stress response 1 and ion co-transporter activity.

SLC12A2 WNK1

2.12e-05466222989884
Pubmed

WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.

SLC12A2 WNK1

2.12e-05466221768522
Pubmed

Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1.

SLC12A2 WNK1

2.12e-05466216669787
Pubmed

WNK kinases sense molecular crowding and rescue cell volume via phase separation.

SLC12A2 WNK1

3.53e-05566236318922
Pubmed

Cloning and characterization of a novel MyoD enhancer-binding factor.

ZNF704 ZNF395

3.53e-05566217693064
Pubmed

Critical role of WNK1 in MYC-dependent early mouse thymocyte development.

SLC12A2 WNK1

9.86e-05866233051000
Pubmed

WNK1 kinase balances T cell adhesion versus migration in vivo.

SLC12A2 WNK1

9.86e-05866227400149
Pubmed

Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development.

OSBPL2 RO60

9.86e-05866221048919
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

ZNF704 KDM5B FLCN ZNF395

1.06e-0412866425332235
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CLPTM1L MYOF NEPRO RPL37A SUPT20H SLC12A2 RTCB NSA2 WRN MBD4 NOL8

1.10e-041497661131527615
Pubmed

B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice.

SLC12A2 WNK1

1.27e-04966236662229
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCA6 ABCA9

1.58e-041066211435397
Pubmed

Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.

SLC12A2 WNK1

2.31e-041266227782176
Pubmed

Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS.

SLC12A2 NSA2 HMGB3

3.00e-046866336966392
Pubmed

Mapping of five subtype genes for muscarinic acetylcholine receptor to mouse chromosomes.

SCN7A CHRM5

4.74e-041766210549128
Pubmed

Gene expression in cortical interneuron precursors is prescient of their mature function.

SLC12A2 POU3F4

5.94e-041966218250082
Pubmed

Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.

CEL CYP7B1

5.94e-041966212721789
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

PKHD1 DNAH11

6.59e-042066217251353
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

CLPTM1L BTN3A3 RPL37A OSBPL2 SLC12A2

7.40e-0437566532788342
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA6 ABCA9

7.99e-04226628894702
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

SUPT20H KIN WRN NOL8

8.54e-0422266437071664
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

MYOF KAT6B OGA WNK1

8.98e-0422566412168954
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

KAT6B WNK1 SEMA3E

1.04e-031046639205841
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

BPI ABCA6 WRN CYP7B1 MBD4

1.24e-0342166519692168
Pubmed

The protein kinase complement of the human genome.

EPHA6 STK32B

1.30e-032866212471243
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

EPHA6 ZMYM6 SEMA3E

1.45e-0311766317145500
Pubmed

Human transcription factor protein interaction networks.

NEPRO RPL37A SUPT20H RTCB NSA2 SPZ1 DGKK HMGB3 RFXAP

1.46e-03142966935140242
Pubmed

Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.

KDM5B NSA2

1.70e-033266214613977
Pubmed

A high-resolution radiation hybrid map of the proximal portion of mouse chromosome 5.

QDPR SEMA3E

1.80e-033366210843805
CytobandEnsembl 112 genes in cytogenetic band chr17q24

ABCA6 ABCA9 ABCA8

3.91e-0498663chr17q24
GeneFamilyATP binding cassette subfamily A

ABCA6 ABCA9 ABCA8

4.48e-0614433805
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

ASAP2 AGAP2

7.35e-04174321291
GeneFamilyActins|Deafness associated genes

OSBPL2 SLC22A4 POU3F4

2.45e-031134331152
GeneFamilyArfGAPs

ASAP2 AGAP2

2.78e-0333432395
ToppCellRV-14._Fibroblast_III|World / Chamber and Cluster_Paper

EPHA6 ABCA6 SCN7A HMGB3 ABCA9 ABCA8

4.89e-081346668c4046ba1f85172915a112499e492c3efe8474c2
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ABCA6 PIK3CG SCN7A CYP7B1 ABCA9 ABCA8

3.20e-0718466667164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellRV-14._Fibroblast_III|RV / Chamber and Cluster_Paper

EPHA6 ABCA6 HMGB3 ABCA9 ABCA8

2.08e-06140665b4fee8eb6bf855b364b00bda3f78e49d851bbca0
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

3.65e-06157665f147e24f2ece82e1c54750868954d09b3c461804
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

3.77e-06158665e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

EPHA6 SCN7A ABCA9 ABCA8 SEMA3E

5.23e-0616966541cb92b0558f0d5a3e511058efd9110258b88ee3
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue|TCGA-Colorectal / Sample_Type by Project: Shred V9

EPHA6 SCN7A ABCA9 ABCA8 SEMA3E

5.23e-0616966591f4b6a14708e701b2af22989004282041777491
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

ABCA6 SCN7A FLCN MBD4 ABCA8

5.23e-0616966584b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF704 MYO9A OGA WNK1 ABCA9

5.86e-06173665869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A2 ABCA6 PKHD1 WNK1 ABCA9

5.86e-061736650c74bdb40e635d906fd180412c23bf7fed61621e
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF704 MYO9A OGA WNK1 ABCA9

5.86e-061736650672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF704 MYO9A OGA WNK1 ABCA9

5.86e-06173665870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF704 MYO9A OGA WNK1 ABCA9

6.20e-061756651ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

6.55e-06177665cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

6.55e-06177665db222faaecbe5600da39277243c4e7e764eb63c9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF704 CEL SCN7A PKHD1 WNK1

6.55e-06177665c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ASAP2 ABCA6 SCN7A ABCA9 ABCA8

6.73e-06178665d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCellILEUM-inflamed-(9)_Neuro_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ASAP2 ABCA6 SCN7A ABCA9 ABCA8

6.73e-06178665611504b0a9e6318b18fba83787b03f9245c82252
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

EPHA6 ABCA6 SCN7A ABCA9 ABCA8

6.92e-06179665dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

8.34e-061866655473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

8.55e-0618766592d468dde81125d51daf7abd4703741abe1ab91c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF ABCA6 SCN7A PKHD1 ABCA9

8.55e-06187665f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

EPHA6 ABCA6 SCN7A ABCA9 ABCA8

8.78e-06188665706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP54 MYO9A STK32B PKHD1 DNAH11

8.78e-0618866563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZCCHC24 SCN7A CYP7B1 ABCA9 ABCA8

9.01e-06189665f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYOF ABCA6 SCN7A PKHD1 ABCA9

9.01e-06189665e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EPHA6 ABCA6 SCN7A ABCA9 ABCA8

9.24e-0619066512992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

9.24e-061906653a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellNeuron-Postmitotic-Inhibitory_Neuron|World / Primary Cells by Cluster

GALNTL6 ZNF704 RPL37A RASGRF2 POU3F4

9.48e-061916654dd9c8117c4499ed9bde127baf2598603a82080d
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

EPHA6 ABCA6 SCN7A ABCA9 ABCA8

9.48e-0619166570c067c54084bfb02c29bab085f4defd477194fb
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

9.48e-061916656688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

EPHA6 ABCA6 SCN7A ABCA9 ABCA8

9.72e-06192665356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

9.72e-0619266599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

9.97e-06193665ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASAP2 SLC12A2 CEL SCN7A WNK1

9.97e-0619366546d5d1f8150ebbc7f1941b96ab184491e5c1210b
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

EPHA6 ABCA6 SCN7A ABCA9 ABCA8

1.02e-0519466511c79a8c56ece42713b04b321982e41e239f07a5
ToppCellControl-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.02e-051946653c2266772c5b56e8e02a461e5193e29588028ee9
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

ASAP2 ABCA6 SCN7A ABCA9 ABCA8

1.02e-05194665234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

ASAP2 ABCA6 SCN7A ABCA9 ABCA8

1.05e-05195665a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.05e-05195665df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.05e-0519566561c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.05e-05195665603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.05e-051956654243190ad291d56694e2155954dbaa879c9d3844
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

EPHA6 ABCA6 SCN7A ABCA9 ABCA8

1.05e-05195665ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ASAP2 SLC12A2 CEL SCN7A WNK1

1.05e-051956653f517c6fc372bdcaf45b3af373414f13cbebd4ba
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.05e-05195665aa0add081881d349099d12efca5cdee098038d4e
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.07e-051966659737a5f006d37b549f281e1863aca558e1e4dc99
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.07e-0519666542e9828222a9663525d571633e8a454c30bfa7f8
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.07e-05196665bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.07e-05196665cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.07e-051966657d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.10e-0519766594a9603cbd3516fbcce871909693b88f20d41713
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA6 SCN7A PKHD1 ABCA9 ABCA8

1.10e-051976656806ec223e542f0475303698eb78c1cc527f5c6b
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.10e-05197665fb847f2277609c31fffcdf49517243ce0684facf
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.10e-0519766513896ec65ccda0b928c91d41112dc01b480036b7
ToppCellCOVID-19-kidney-Fibroblast-2|kidney / Disease (COVID-19 only), tissue and cell type

ZCCHC24 ABCA6 LRRK1 ABCA9 ABCA8

1.13e-05198665ca26ca460856b1faaa3e83766da6abdf63af2b51
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.13e-05198665df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.13e-051986658f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.13e-05198665f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.16e-0519966528c1722deef3b8347371c7359be7c64b95780de3
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

ZCCHC24 BPI ABCA6 ABCA9 ABCA8

1.16e-0519966512133087eae9f0e9b6c13a71e8187117768e64ce
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.16e-051996654bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellBiopsy_Control_(H.)-Mesenchymal-Myofibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.16e-051996657a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA6 RASGRF2 SCN7A ABCA9 ABCA8

1.16e-051996653835452e4848d7f7dd8651c17b746b271ef39688
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA6 RASGRF2 SCN7A ABCA9 ABCA8

1.16e-051996659c2db0bb94cba71a3cc1827844da090e213e0258
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.16e-0519966566a79732caf2f04c09b4d9832377aa01ca477677
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 RASGRF2 CYP7B1 ABCA9 ABCA8

1.18e-05200665032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellmedial-mesenchymal-Alveolar_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCelldistal-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-0520066512b705dabec1b3752a488a891eda1a5123fcdc41
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 RASGRF2 CYP7B1 ABCA9 ABCA8

1.18e-0520066568fce28690246895fd33354b30960ebcc31aa4cc
ToppCellmedial-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 RASGRF2 CYP7B1 ABCA9 ABCA8

1.18e-05200665376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665a510deaada669e690329183e18df02870bd204b3
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-052006656e3d1ae0ef84d3075afa40129a41169996462672
ToppCellmedial-mesenchymal-Alveolar_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-052006655c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 RASGRF2 CYP7B1 ABCA9 ABCA8

1.18e-052006657fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-0520066525d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ZCCHC24 CHST14 ABCA6 ABCA9 ABCA8

1.18e-052006653e0041c04e42a47257517dae8707a6454570c256
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 RASGRF2 CYP7B1 ABCA9 ABCA8

1.18e-05200665878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

SLC12A2 RASGRF2 CYP7B1 ABCA9 ABCA8

1.18e-052006657136936d05ab344a560cf159684c881063b5430d
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA6 SCN7A CYP7B1 ABCA9 ABCA8

1.18e-05200665dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BTN3A3 DGKK TNK2 AGAP2

4.56e-051336642ec3490cbf60152c3cece95eb566d749c9666517
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

ZCCHC24 SLC12A2 SCN7A SEMA3E

7.47e-051516645906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCellAdult-Immune-dendritic_cell-D122|Adult / Lineage, Cell type, age group and donor

PIK3CG DGKK LRRK1 RFXAP

8.07e-0515466464a4686586d08b1e9632dde917b472ac660de2d3
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIK3CG PKHD1 FHDC1 IL17RB

8.48e-0515666458b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CEL ABCA6 SCN7A WNK1

8.48e-051566644d2679e7639758c49fc25a2deb9109b08f0a3e57
ToppCellTCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-9|TCGA-Colorectal / Sample_Type by Project: Shred V9

EPHA6 SCN7A ABCA9 SEMA3E

9.13e-05159664f376bf6cd0ed374211edac3c384f3a78f0caef2a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZCCHC24 ABCA6 ACSBG2 ABCA8

9.13e-05159664330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZCCHC24 ABCA6 ACSBG2 ABCA8

9.13e-05159664cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ASAP2 SLC12A2 CEL WNK1

9.81e-0516266436ddebe3bb172c992739353b7b049b2dde98b559
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 LRRK1 ABCA9 ABCA8

1.00e-04163664bbc078761c5043af13d9a6fcf3145a3e300bae5e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 LRRK1 ABCA9 ABCA8

1.00e-041636648e32b6431e1862572663aa6ddc4ea299c6acc8a6
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

ASAP2 ABCA6 SCN7A ABCA8

1.05e-041656646ed52cb756d21addf46c7f6c457458b01339fe04
ToppCellCOVID-19-Heart-Neuronal|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZCCHC24 ABCA6 SCN7A ABCA8

1.13e-0416866488c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA6 SCN7A ABCA9 ABCA8

1.13e-041686644b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MTX2 OSBPL2 RASGRF2 RO60

1.15e-04169664c135d7ae0490d0024e0f4bd8c4ad42f6674a61da
Diseaseperipheral neuropathy

GALNTL6 SCN7A

9.96e-057652EFO_0003100
DiseaseColorectal Carcinoma

ABCA6 RASGRF2 WRN PKHD1 FLCN WNK1 ABCA9 ABCA8

1.51e-04702658C0009402
Diseaseresponse to statin, myopathy

SLC12A2 RASGRF2

2.59e-0411652EFO_0004145, GO_0036273
Diseaseuric acid measurement

MYOF ASAP2 CEL ABCA6 MYO9A SLC22A4 STK32B

3.84e-04610657EFO_0004761
DiseaseMental deterioration

GALNTL6 DNAH11

1.87e-0329652HP_0001268

Protein segments in the cluster

PeptideGeneStartEntry
AKSMGLKKKAFVWAR

ACSBG2

336

Q5FVE4
VLQKLWECTKMKFGT

CFAP54

1496

Q96N23
VCSKNVERKKGWVKM

BTN3A3

411

O00478
LCKNCLKKWRMKRQT

ABCA9

16

Q8IUA7
LCKNFLKKWRMKRES

ABCA6

16

Q8N139
MKQCRKEIKLLKGLW

DNAH11

1316

Q96DT5
AEAKRKMWKLKSFGS

AGAP2

851

Q99490
KSKSLFKNCDLMWKQ

QDPR

96

P09417
KKKFMTEQLRKLGRW

C5orf52

126

A6NGY3
WQGTLKAKNFKKRCL

CEL

71

P19835
RKALCKRKSWMSKVF

TNK2

66

Q07912
KRKSWMSKVFSGKRL

TNK2

71

Q07912
RKKKAWKRMVTKVCF

NSA2

141

O95478
MWICQVCRPKKKGRK

KAT6B

311

Q8WYB5
IKSKGLQKLRWYCQM

KIN

16

O60870
LGKKKRMRSFFWKTI

FHDC1

91

Q9C0D6
GPMLKNCNSFKRWKL

DGKK

221

Q5KSL6
CLKEEWMNKVKVLFK

FLCN

506

Q8NFG4
VNWKKKKSGGMKIVC

LRRK1

1106

Q38SD2
KVWQKRKCSVKNGFL

ASAP2

321

O43150
IMKYKKKCVKAGSLW

IL17RB

166

Q9NRM6
KKCWENIKARTKKIM

MSANTD3

71

Q96H12
VCKDRKWTKIATKMG

KDM5B

146

Q9UGL1
KKCMSVLNKTKWKGG

NOL8

66

Q76FK4
FCGKTKMKRRAVGIW

RPL37A

41

P61513
SFKNMCKLKPLLNKW

POU3F4

241

P49335
KWKAQKRFLKMSGNF

BPI

121

P17213
MCLWLWKQFLKRGSK

C6orf50

46

Q9HD87
WNLRTRSKCKKDVFM

MBD4

176

O95243
FSKKCSERWKTMSGK

HMGB3

41

O15347
IKCFSSEKLAKMQGW

CYP7B1

246

O75881
KAMQRLAKKMSGWFL

ERCC6L2

366

Q5T890
QMQKVKWFRSGKKTR

SLC22A4

521

Q9H015
ITGRCQWYIKAKMKS

EPHA6

571

Q9UF33
KRKMKAIGWGKKTLD

MTX2

166

O75431
LRKQLKCKDFKWFMA

GALNTL6

421

Q49A17
FLEKINKNCWRIKKG

RTCB

11

Q9Y3I0
TLKKMWITAFCKQIK

NXPE2

331

Q96DL1
KKCKISWIPFMQEKY

OGA

791

O60502
IKKIKKVQSFMRGWL

RASGRF2

206

O14827
MAVVWCRSKKLKAQA

NEPRO

376

Q6NW34
KFMKICALTKKGRNW

WRN

1036

Q14191
VFNKGKSMVHKKAWL

PKHD1

231

P08F94
SQVAKQRKPWMCKKH

RFXAP

151

O00287
KESMKCGMWGRALRK

RO60

136

P10155
NKKKLFMIYGKWTEC

OSBPL2

291

Q9H1P3
LCKNFLKKWRMKRES

ABCA8

16

O94911
TLRCLEWKFGKKSMR

ABCA8

1216

O94911
FKMLLLCRWKKKKVE

CHRM5

506

P08912
KNDISFWKKKKSMIG

CLPTM1L

306

Q96KA5
KVACSNWKRVMKVLA

CHST14

156

Q8NCH0
CKVMASKKKPLWLEF

PIK3CG

801

P48736
FIGLVNCMDWVKKRK

TAS2R7

26

Q9NYW3
KRKSPAQVMFQCLWK

SLC2A4RG

191

Q9NR83
KKKWKDCKIRVFIGG

SLC12A2

1046

P55011
LKISKAGNCVDMWKR

SUPT20H

281

Q8NEM7
KRKNSVKVMYKCLWP

ZNF395

271

Q9H8N7
NVRQTVMKWSKGKCK

ZNF654

776

Q8IZM8
VMKWSKGKCKFCQRQ

ZNF654

781

Q8IZM8
VMFKCLWKNCGKVLS

ZNF704

191

Q6ZNC4
CNKIDVFKRKLKMWL

ZMYM6

1141

O95789
KGKIWQNIRKTCCKI

SCN7A

916

Q01118
KVWCTDRKRKKLKMS

SEMA3E

731

O15041
WCKGMVALLRKLLTK

STK32B

251

Q9NY57
QAMKGTFWKKDRSCR

SPZ1

381

Q9BXG8
FKVMKIKVLRSWCRQ

WNK1

316

Q9H4A3
KCGQRRLKMFSQEKW

ZNF831

606

Q5JPB2
KCPKCKRKWMSGNSW

ZCCHC24

171

Q8N2G6
AKMRFWAKGKQGEKK

MYO9A

1756

B2RTY4
NPCKTMKFIVWRRFK

MYOF

2011

Q9NZM1