Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved SA node cell action potential

CACNA1D CACNA1G

1.01e-052642GO:0086059
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1D CACNA1G

1.01e-045642GO:0086007
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

FOXM1 TBX19 KMT2C SP100 HOXB9 VENTX CES1 NFIB CALCOCO1 MAMSTR ZNF521 DLX3 NOTCH2 NOTCH3 CHUK

1.40e-0513906315GO:0045944
GeneOntologyBiologicalProcessresponse to nickel cation

CACNA1G LCT

2.75e-053632GO:0010045
GeneOntologyBiologicalProcessmembrane depolarization during SA node cell action potential

CACNA1D CACNA1G

9.13e-055632GO:0086046
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

1.37e-046632GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

1.37e-046632GO:0072104
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH2 NOTCH3

1.91e-047632GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH2 NOTCH3

1.91e-047632GO:0061439
GeneOntologyCellularComponentGolgi lumen

MUC16 MUC5B MUC12 MUC3A MUC20

2.44e-05109665GO:0005796
DomainDUF3454

NOTCH2 NOTCH3

3.46e-053642PF11936
DomainDUF3454_notch

NOTCH2 NOTCH3

3.46e-053642IPR024600
DomainDUF3454

NOTCH2 NOTCH3

3.46e-053642SM01334
DomainSEA

MUC16 MUC12 MUC3A

6.47e-0523643PS50024
DomainSEA_dom

MUC16 MUC12 MUC3A

6.47e-0523643IPR000082
DomainLRRC37AB_C

LRRC37A LRRC37A2

6.90e-054642PF14914
DomainNotch

NOTCH2 NOTCH3

6.90e-054642IPR008297
DomainNODP

NOTCH2 NOTCH3

6.90e-054642PF07684
DomainNotch_NODP_dom

NOTCH2 NOTCH3

6.90e-054642IPR011656
DomainNotch_NOD_dom

NOTCH2 NOTCH3

6.90e-054642IPR010660
DomainLRRC37_N

LRRC37A LRRC37A2

6.90e-054642IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A2

6.90e-054642IPR029423
DomainNOD

NOTCH2 NOTCH3

6.90e-054642PF06816
DomainLRRC37

LRRC37A LRRC37A2

6.90e-054642PF15779
DomainNOD

NOTCH2 NOTCH3

6.90e-054642SM01338
DomainNODP

NOTCH2 NOTCH3

6.90e-054642SM01339
DomainLRRC37A/B-like

LRRC37A LRRC37A2

6.90e-054642IPR015753
DomainLNR

NOTCH2 NOTCH3

1.15e-045642PS50258
DomainNotch_dom

NOTCH2 NOTCH3

2.40e-047642IPR000800
DomainNotch

NOTCH2 NOTCH3

2.40e-047642PF00066
DomainNL

NOTCH2 NOTCH3

2.40e-047642SM00004
DomainVDCCAlpha1

CACNA1D CACNA1G

5.11e-0410642IPR002077
DomainSEA

MUC16 MUC3A

1.02e-0314642SM00200
DomainUBA-like

UBAP2 TNRC6A UBALD1

1.38e-0364643IPR009060
DomainEGF_1

MUC12 USH2A MUC3A NOTCH2 NOTCH3

1.80e-03255645PS00022
DomainSEA

MUC16 MUC12

2.55e-0322642PF01390
DomainhEGF

NOTCH2 NOTCH3

4.13e-0328642PF12661
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC12 MUC3A ADAMTSL4 NOTCH2 NOTCH3 MUC20

3.59e-1168458M27303
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC12 MUC3A MUC20

1.12e-0916455M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC12 MUC3A MUC20

1.59e-0917455M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC12 MUC3A MUC20

8.50e-0923455M556
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC12 MUC3A ADAMTSL4 NOTCH2 NOTCH3 MUC20

1.45e-08143458M27275
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC12 MUC3A MUC20

1.65e-0826455M27483
PathwayREACTOME_DISEASES_OF_METABOLISM

MUC16 MUC5B MUC12 LCT MUC3A ADAMTSL4 NOTCH2 NOTCH3 MUC20

7.63e-08250459M27554
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC12 MUC3A ADAMTSL4 MUC20

1.32e-06111456M27416
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC12 MUC3A MUC20

1.49e-0662455M546
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC16 MUC5B MUC12 MUC3A CHUK MUC20

5.10e-06140456M27484
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC20

3.88e-0521453MM15706
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH2 NOTCH3 CHUK

8.43e-0527453M39545
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH2 NOTCH3

9.90e-055452M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH2 NOTCH3

1.48e-046452M27068
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B ADAMTSL4 MUC20

3.95e-04109454MM15164
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH2 NOTCH3

5.38e-0411452M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH2 NOTCH3

6.44e-0412452M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH2 NOTCH3

6.44e-0412452M47533
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3

7.60e-0413452M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH2 NOTCH3

7.60e-0413452M47534
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC20

9.16e-0460453MM15636
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH2 NOTCH3

1.48e-0318452M614
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC12 MUC3A MUC20

2.23e-101869518834073
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12 MUC20

7.47e-09369326770020
Pubmed

Expression of notch family proteins in placentas from patients with early-onset severe preeclampsia.

NOTCH2 NOTCH3

3.88e-06269224336671
Pubmed

NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.

NOTCH2 NOTCH3

3.88e-06269234257585
Pubmed

Concomitant genetic ablation of L-type Cav1.3 (α1D) and T-type Cav3.1 (α1G) Ca2+ channels disrupts heart automaticity.

CACNA1D CACNA1G

3.88e-06269233144668
Pubmed

Notch3 null mutation in mice causes muscle hyperplasia by repetitive muscle regeneration.

DMD NOTCH3

3.88e-06269220960513
Pubmed

Notch signaling modulates MUC16 biosynthesis in an in vitro model of human corneal and conjunctival epithelial cell differentiation.

MUC16 NOTCH3

3.88e-06269221508102
Pubmed

Effects of Notch2 and Notch3 on Cell Proliferation and Apoptosis of Trophoblast Cell Lines.

NOTCH2 NOTCH3

3.88e-06269226640406
Pubmed

Notch2 and Notch3 function together to regulate vascular smooth muscle development.

NOTCH2 NOTCH3

3.88e-06269222615991
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1D CACNA1G

1.16e-05369224966091
Pubmed

Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.

CACNA1D CACNA1G

1.16e-05369221406960
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH2 NOTCH3

1.16e-0536927615640
Pubmed

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium.

NOTCH2 NOTCH3

1.16e-0536927918097
Pubmed

Complementary and combinatorial patterns of Notch gene family expression during early mouse development.

NOTCH2 NOTCH3

1.16e-0536928645602
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

1.16e-05369227230679
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC20

1.16e-05369230236127
Pubmed

Expression of Notch1 to -4 and their ligands in renal cell carcinoma: a tissue microarray study.

NOTCH2 NOTCH3

1.16e-05369221471519
Pubmed

Effect of notch1,2,3 genes silicing on NF-κB signaling pathway of macrophages in patients with atherosclerosis.

NOTCH2 NOTCH3

1.16e-05369227697639
Pubmed

Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia.

CACNA1D CACNA1G

1.16e-05369232555258
Pubmed

Rab3-interacting molecules 2α and 2β promote the abundance of voltage-gated CaV1.3 Ca2+ channels at hair cell active zones.

CACNA1D RIMS1

1.16e-05369226034270
Pubmed

Overlapping but distinct roles for NOTCH receptors in human cardiovascular disease.

NOTCH2 NOTCH3

1.16e-05369229767458
Pubmed

The human NOTCH1, 2, and 3 genes are located at chromosome positions 9q34, 1p13-p11, and 19p13.2-p13.1 in regions of neoplasia-associated translocation.

NOTCH2 NOTCH3

1.16e-0536927698746
Pubmed

T-cell acute lymphoblastic leukemia in infants has distinct genetic and epigenetic features compared to childhood cases.

NOTCH2 NOTCH3

1.16e-05369227717083
Pubmed

Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.

NOTCH2 NOTCH3

1.16e-05369225957400
Pubmed

Is KIF24 a genetic risk factor for Frontotemporal Lobar Degeneration?

UBAP2 KIF24

1.16e-05369220670673
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

UBAP2 TNRC6A KDM3B MUC16 MUC3A ADAMTSL4 KIF24 MUC20

1.37e-0555269810737800
Pubmed

PDK1 Is a Regulator of Epidermal Differentiation that Activates and Organizes Asymmetric Cell Division.

NOTCH2 NOTCH3 CHUK

1.67e-052569327184845
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH2 NOTCH3

2.32e-05469228061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH2 NOTCH3

2.32e-05469224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH2 NOTCH3

2.32e-05469220069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH2 NOTCH3

2.32e-05469219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH2 NOTCH3

2.32e-05469228669409
Pubmed

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods.

NOTCH2 NOTCH3

2.32e-05469210551863
Pubmed

A deficiency of lunatic fringe is associated with cystic dilation of the rete testis.

NOTCH2 NOTCH3

2.32e-05469218801836
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH2 NOTCH3

2.32e-05469211466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH2 NOTCH3

2.32e-05469224151014
Pubmed

Notch2 is required for maintaining sustentacular cell function in the adult mouse main olfactory epithelium.

NOTCH2 NOTCH3

2.32e-05469218155189
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH2 NOTCH3

2.32e-05469211401408
Pubmed

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors.

NOTCH2 NOTCH3

2.32e-05469223999936
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH2 NOTCH3

2.32e-05469210194420
Pubmed

NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells.

NOTCH2 NOTCH3

2.32e-05469218156632
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH2 NOTCH3

2.32e-0546928898100
Pubmed

Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing.

NOTCH2 NOTCH3

2.32e-05469211978185
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH2 NOTCH3

2.32e-05469211459941
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A2

2.32e-05469222419166
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH2 NOTCH3

2.32e-05469218184405
Pubmed

Notch Signaling Participates in TGF-β-Induced SOST Expression Under Intermittent Compressive Stress.

NOTCH2 NOTCH3

2.32e-05469227966788
Pubmed

MicroRNA miR145 regulates TGFBR2 expression and matrix synthesis in vascular smooth muscle cells.

NOTCH2 NOTCH3

2.32e-05469225323858
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH2 NOTCH3

2.32e-05469215917835
Pubmed

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

NOTCH2 NOTCH3

2.32e-05469228084316
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH2 NOTCH3

2.32e-05469223444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH2 NOTCH3

2.32e-05469217920003
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

NOTCH2 NOTCH3

3.86e-05569221726900
Pubmed

Notch signaling in bulge stem cells is not required for selection of hair follicle fate.

NOTCH2 NOTCH3

3.86e-05569219211676
Pubmed

A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons.

NOTCH2 NOTCH3

3.86e-05569227040987
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH2 NOTCH3

3.86e-05569221124806
Pubmed

MASTR directs MyoD-dependent satellite cell differentiation during skeletal muscle regeneration.

MAMSTR DMD

3.86e-05569222279050
Pubmed

Assignment of the murine Notch2 and Notch3 genes to chromosomes 3 and 17.

NOTCH2 NOTCH3

3.86e-0556929570965
Pubmed

The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGFβ and Notch pathways.

NOTCH2 NOTCH3

3.86e-05569228747678
Pubmed

Functional diversity of notch family genes in fetal lung development.

NOTCH2 NOTCH3

3.86e-05569215064243
Pubmed

A novel tumour-suppressor function for the Notch pathway in myeloid leukaemia.

NOTCH2 NOTCH3

3.86e-05569221562564
Pubmed

Notch3 and pre-TCR interaction unveils distinct NF-kappaB pathways in T-cell development and leukemia.

NOTCH3 CHUK

3.86e-05569216498412
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH2 NOTCH3

3.86e-05569223675950
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH2 NOTCH3

3.86e-05569211101851
Pubmed

Notch expression in developing olfactory neuroepithelium.

NOTCH2 NOTCH3

3.86e-05569215076712
Pubmed

Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects.

NOTCH2 NOTCH3

3.86e-05569216899352
Pubmed

Developmental expression patterns of alpha1H T-type Ca2+ channels during spermatogenesis and organogenesis in mice.

CACNA1D CACNA1G

3.86e-05569212060068
Pubmed

Chimeric analysis of Notch2 function: a role for Notch2 in the development of the roof plate of the mouse brain.

NOTCH2 NOTCH3

3.86e-05569212242712
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH2 NOTCH3

3.86e-05569215882997
Pubmed

Pax7, Pax3 and Mamstr genes are involved in skeletal muscle impaired regeneration of dy2J/dy2J mouse model of Lama2-CMD.

MAMSTR DMD

3.86e-05569231348492
Pubmed

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.

TBX19 NOTCH2 NOTCH3

4.28e-053469317015435
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

KMT2C UBAP2 CALCOCO1 TNRC6A

5.41e-0510369410819331
Pubmed

Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification.

TBX19 NOTCH2 NOTCH3

5.53e-053769324673559
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH2 NOTCH3

5.79e-0566929111338
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH2 NOTCH3

5.79e-05669220870902
Pubmed

The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.

NOTCH2 NOTCH3

5.79e-05669226062937
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC16 MUC5B

5.79e-05669219110483
Pubmed

ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway.

NOTCH2 NOTCH3

5.79e-05669224671051
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH2 NOTCH3

5.79e-05669212244553
Pubmed

Profiling immunohistochemical expression of NOTCH1-3, JAGGED1, cMET, and phospho-MAPK in 100 carcinomas of unknown primary.

NOTCH2 NOTCH3

5.79e-05669222526456
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH2 NOTCH3

5.79e-05669219503073
Pubmed

Epidermal Notch1 loss promotes skin tumorigenesis by impacting the stromal microenvironment.

NOTCH2 NOTCH3

5.79e-05669219573812
Pubmed

p14ARF interacts with N-Myc and inhibits its transcriptional activity.

NOTCH3 CHUK

5.79e-05669217289033
Pubmed

Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.

NOTCH2 NOTCH3

5.79e-05669211731257
Pubmed

Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura.

NOTCH2 NOTCH3

5.79e-05669219603167
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH2 NOTCH3

5.79e-05669218299578
Pubmed

Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.

NOTCH2 NOTCH3

5.79e-0566929108364
Pubmed

Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.

NOTCH2 NOTCH3

5.79e-0566929882480
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH2 NOTCH3

5.79e-05669215019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH2 NOTCH3

5.79e-05669222615412
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH2 NOTCH3

5.79e-05669221991352
Pubmed

Niclosamide inhibits colon cancer progression through downregulation of the Notch pathway and upregulation of the tumor suppressor miR-200 family.

NOTCH2 NOTCH3

5.79e-05669227460529
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

MUC5B NOTCH2 NOTCH3

7.55e-054169322675208
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

NOTCH2 NOTCH3

8.09e-05769210383933
Pubmed

Human ligands of the Notch receptor.

NOTCH2 NOTCH3

8.09e-05769210079256
Pubmed

Loss of Notch2 and Notch3 in vascular smooth muscle causes patent ductus arteriosus.

NOTCH2 NOTCH3

8.09e-05769226453897
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1D CACNA1G

8.09e-05769212900400
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH2 NOTCH3

8.09e-05769212846471
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH2 NOTCH3

8.09e-05769211518718
Pubmed

Differentiation of CD11c+ CX3CR1+ cells in the small intestine requires Notch signaling.

NOTCH2 NOTCH3

8.09e-05769224711412
Cytoband9p13.3

UBAP2 KIF24 RUSC2

2.03e-04756939p13.3
CytobandEnsembl 112 genes in cytogenetic band chr17q21

HOXB9 LRRC37A LRRC37A2 CACNA1G DLX3

7.43e-04473695chr17q21
Cytoband7q22

MUC12 MUC3A

1.51e-03386927q22
CytobandEnsembl 112 genes in cytogenetic band chr9p13

UBAP2 KIF24 RUSC2

2.33e-03174693chr9p13
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC12 MUC3A MUC20

6.20e-1021385648
GeneFamilyCalcium voltage-gated channel subunits

CACNA1D CACNA1G

1.35e-0326382253
ToppCellnucseq-Epithelial-Epithelial_Glandular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL17A1 MUC16 MUC5B INAVA RIMS1 MUC3A MUC20

1.23e-08179697859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL17A1 MUC16 MUC5B INAVA RIMS1 MUC3A MUC20

1.28e-081806973dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCellnucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL17A1 MUC16 MUC5B INAVA RIMS1 MUC3A MUC20

1.28e-08180697668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

MUC16 MUC5B DMBT1 NOTCH2 SLC38A8 MUC20

3.01e-07174696ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

MUC16 MUC5B DMBT1 NOTCH2 SLC38A8 MUC20

3.21e-07176696cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BNIP5 MUC16 MUC5B RIMS1 MUC20

7.22e-071086959c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCellParenchymal-10x5prime-Epithelial-Epi_submucosal-gland|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

BNIP5 MUC16 MUC5B RIMS1 MUC20

7.22e-0710869575d635fc5bb004418db2e1328c24d96b718f10b1
ToppCellLPS-antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNIP5 ATG9B LCT CHRM3 IL5RA

2.99e-06144695013223bb2f31eb5bebdbd0908b797d28b96c6f7b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BNIP5 HOXB9 CAPS FAM117B SLC14A2

4.56e-0615769510989c7046fc859f137c7cef3296508d4476f11f
ToppCellRSV-Healthy-6|Healthy / Virus stimulation, Condition and Cluster

ATG9B EVC2 TAF1C SIGLEC10 IL5RA

5.63e-061646951b9c5a6dc4e09b90f92e98b81a5ee620f8479cc7
ToppCellRSV-Healthy-6|RSV / Virus stimulation, Condition and Cluster

ATG9B EVC2 TAF1C SIGLEC10 IL5RA

5.63e-06164695ab312b8c2f828ea7331f2a340c4df81587a23b5c
ToppCellClub_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MUC5B RIMS1 SLC38A8 NOTCH3 MUC20

6.15e-06167695dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DLEC1 MUC12 PLAC4 KIF24 IL5RA

6.90e-0617169552aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCellClub_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MUC5B INAVA RIMS1 DMBT1 NOTCH3

8.39e-06178695be64d4be23fb96a4cdd7980c58880fdfe817747f
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ATG9B DLEC1 MUC12 KIF24 IL5RA

9.34e-06182695000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellControl-Epithelial_cells-Airway_mucous|Control / group, cell type (main and fine annotations)

COL17A1 MUC16 MUC5B INAVA MUC3A

9.59e-0618369515d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCellControl-Epithelial_cells-Airway_goblet|Control / group, cell type (main and fine annotations)

COL17A1 MUC16 MUC5B RIMS1 MUC3A

9.85e-06184695d92a71441e4e19f8c301999d8186f8e48e3cd162
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|343B / Donor, Lineage, Cell class and subclass (all cells)

MUC5B INAVA RIMS1 NOTCH3 MUC20

1.12e-05189695b06471b1bebb990d5146bddfb8002401c6b099a0
ToppCell343B-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|343B / Donor, Lineage, Cell class and subclass (all cells)

MUC5B INAVA RIMS1 NOTCH3 MUC20

1.12e-05189695a8246acf31f02c85421268245afb651aa8788f14
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D DMD ADAMTSL4 NOTCH2 NOTCH3

1.12e-0518969545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PROSER3 KIAA1549 MUC12 KIF24 SLC38A8

1.15e-05190695250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellClub|World / shred by cell class for parenchyma

CAPS MUC5B INAVA RIMS1 MUC20

1.15e-051906951974d559d7fee6cb68065b18af8bd38b64910622
ToppCell(7)_Epithelial-G_(Club-Clara_cells)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CAPS MUC5B INAVA RIMS1 NOTCH3

1.15e-05190695593fd1451038b155826a48de4caa38f44406d0b9
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXM1 BNIP5 UBALD1 SLC38A8

1.22e-0591694b0658e020f80e56fab9d2aa07e321d9b33d7af2c
ToppCellClub_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B INAVA RIMS1 NOTCH3

1.24e-051936956582c0367052b9d10fb629c383ee0c55872afd2d
ToppCellClub_cells|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B INAVA RIMS1 NOTCH3

1.24e-051936959d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell3'-Distal_airway|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CES1 CAPS MUC5B DLEC1 IL5RA

1.27e-05194695e9ff4398e880d13894e52c0ba9cf19a7662c248b
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BNIP5 HOXB9 MUC5B INAVA MUC3A

1.27e-0519469507d8e38cbc2c7f0564c14f7c365f345f901b73b2
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B INAVA RIMS1 NOTCH3

1.30e-05195695b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell(01)_IL1RL1+-(1)_GFP|(01)_IL1RL1+ / shred by cell type by condition

MAP7D1 COL17A1 MUC5B INAVA ADAMTSL4

1.34e-05196695b598b1112242534e139318012b257ed3cb09da83
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CES1 CAPS MUC16 DLX3 RIMS1

1.34e-05196695d9426eba69047166ffa8179f1654e011c1020328
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CES1 CAPS MUC16 DLX3 RIMS1

1.34e-051966957e19919eafd6ddf547dd4e8aa532a050e182c5cc
ToppCell15-Trachea|15 / Age, Tissue, Lineage and Cell class

CAPS MUC16 MUC5B DLEC1 MUC20

1.34e-05196695fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCellAT2_cells-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

BNIP5 COL17A1 MUC5B DMBT1 MUC3A

1.37e-051976955e0d222872a25bb9e9069d3dffda2844bb69874a
ToppCellBL-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CES1 NFIB CAPS MUC16 MUC20

1.40e-051986956218a25b94d5fa2c69880539adf9c63bfe52dcd3
ToppCellproximal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 MUC5B INAVA RIMS1 MUC20

1.40e-051986953477202c4f702d8f75231b13d4b5216f56d981d7
ToppCellproximal-Epithelial-Goblet|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 MUC5B INAVA RIMS1 MUC20

1.40e-05198695e7e1c430486a81280abc4a7e7f5bc3713dd20737
ToppCellBL-critical-LOC-Epithelial-Secretory_LYPD2|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NFIB CAPS MUC16 MUC5B RIMS1

1.40e-05198695484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCellproximal-Epithelial-Goblet-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MUC16 MUC5B INAVA RIMS1 MUC20

1.40e-05198695da7b40eb00bb5e454e1cfcd1219dc0d84712592a
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B INAVA RIMS1 MUC20

1.44e-05199695d04062d86643e5712cc2f519f4f36e643d404a16
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MUC16 MUC5B INAVA RIMS1 MUC20

1.44e-05199695a3f83fe5c3c557cd3ef8f5632f7fba5cf1859937
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

MUC16 MUC5B INAVA RIMS1 MUC20

1.44e-05199695644197ff7e3299587881dd678836262e670ed4a8
ToppCell(04)_Interm._basal>secr.|World / shred by cell type by condition

MUC16 MUC5B NOTCH2 NOTCH3 MUC20

1.44e-05199695ed399244433f781fc291a9bff16825b8a3ca294f
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

KIAA1549 TMEM131 DMD NOTCH2 NOTCH3

1.44e-05199695358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CAPS MUC16 MUC5B RIMS1 MUC20

1.44e-05199695a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCellSevere_COVID-19-Epithelial-Basal/Club|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

MUC16 MUC5B INAVA RIMS1 MUC20

1.44e-051996952a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCellBAL-Severe-Epithelial-Epithelial-Basal/Club-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MUC16 MUC5B INAVA RIMS1 MUC20

1.44e-05199695fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCellBiopsy_Control_(H.)-Epithelial-MUC5AC+_High|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MUC16 MUC5B RIMS1 NOTCH3 MUC20

1.44e-05199695a5240868cea40574ed4ee45eb27a00c1812957ed
ToppCellBiopsy_Other_PF-Epithelial-KRT5-/KRT17+|Biopsy_Other_PF / Sample group, Lineage and Cell type

BNIP5 COL17A1 MUC3A NOTCH3 MUC20

1.47e-05200695077e6b9340686de9d0f11b035a8954e1f6a1b790
ToppCellNS-moderate-d_0-4-Epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CES1 NFIB CAPS MUC16 MUC20

1.47e-0520069564462a18afca3c1a8548a857924b8166058bf958
ToppCellTracheal|World / Cell types per location group and 10X technology with lineage, and cell group designations

NFIB MUC16 MUC5B DMD CHRM3

1.47e-05200695682960e28542a3d6c119047cd0131941932cfdea
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIAA1549 MUC16 MUC5B RIMS1 CHRM3

1.47e-05200695ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellLPS-IL1RA-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SIGLEC10 CHRM3 IL5RA SLC38A8

6.45e-05139694f1d1a51a79afdddc82e73cd29b3240e3e973db28
ToppCellfacs-Aorta-Heart-3m-Epithelial-epithelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR BNIP5 MUC5B MUC20

8.90e-051516940de76acd1b204345dce7f33be2a1ed9fbe9e6da0
ToppCellfacs-Aorta-Heart-3m-Epithelial-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR BNIP5 MUC5B MUC20

8.90e-0515169420b9c8fb966c5d62ff909cc4a4616b109b78cdca
ToppCellfacs-Aorta-Heart-3m-Epithelial|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR BNIP5 MUC5B MUC20

8.90e-05151694bee48137d1f5f27a24571a59c835284651d38538
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PROSER3 DLEC1 USH2A IL5RA

9.60e-051546949ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PROSER3 DLEC1 USH2A IL5RA

9.60e-0515469458072ce422d09f2de602580325eaac6c4ec6c136
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAPS MUC16 MUC5B RIMS1

1.03e-04157694c43f2e1ea53b375a7432f17f87cfef3b2261003d
ToppCell10x5'-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

FOXM1 TICRR KIAA1549 KIF24

1.03e-04157694d4da4057917dda066da0f2aac2621fdaf1fb943b
ToppCellChildren_(3_yrs)-Immune-mast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF521 KIAA1549 PLAC4 IL5RA

1.03e-04157694ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CAPS MUC5B DLX3 RIMS1

1.06e-0415869403281e87780e3bacd089903383c016d03c373bf7
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNIP5 MUC16 MUC5B RIMS1

1.09e-0415969460b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC5B INAVA MUC3A MUC20

1.11e-04160694028b5261a1da832d52f66fb620db83e5fbbd874a
ToppCellPND07-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MUC5B INAVA MUC3A MUC20

1.11e-041606941f4ee446436726c3d373f56d87dd80b6a12e8b9e
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B RIMS1 MUC20

1.14e-041616942d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CES1 MUC5B DLEC1 MUC20

1.14e-04161694472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCellClub_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NFIB MUC5B RIMS1 NOTCH3

1.28e-04166694a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCellnormal_Pleural_Fluid-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

FOXM1 COL17A1 DMBT1 CAPN15

1.28e-04166694d16af6570806ed2880bd0efb5298932fd2a89cf5
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1D SP100 UBAP2 SMG7

1.31e-04167694774f3264318b002d0df5d06d41d645366038d0bf
ToppCellNS-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIAA1549 MUC12 KIF24 SLC38A8

1.40e-04170694f6a0162bb690dbc19ff1cec64cb933744ad3b496
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Basal_1|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

FOXM1 PROSER3 MUC5B INAVA

1.40e-04170694aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCellHealthy_donor-HSPC|Healthy_donor / disease group, cell group and cell class (v2)

NFIB ZNF521 CHRM3 NOTCH3

1.47e-04172694bc7549faadfc92c683c0e26bea380458706774b5
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MUC16 MUC5B RIMS1 MUC20

1.50e-04173694d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

MAMSTR ZNF521 DLEC1 UBALD1

1.50e-04173694d4cbeae262abfa30d8c5452285d3261a96875610
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B INAVA RIMS1

1.50e-04173694464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell3'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1D HOXB9 MUC5B INAVA

1.50e-0417369481c36b9fe02c59099f080b2db02f4eaf2783911f
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXM1 ZNF521 STK11IP KIF24

1.54e-0417469472df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOXM1 ZNF521 STK11IP KIF24

1.54e-04174694c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SIGLEC10 ZNF521 KIAA1549 IL5RA

1.54e-0417469464d13a7a9757e85f4f4af876c687dd18a7efa01a
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

MUC16 MUC5B RIMS1 NOTCH3

1.54e-041746947d2f802f493f19a068e097b2909a9000e2160266
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FOXM1 TICRR ATG9B MORN1

1.57e-04175694a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCellfacs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B DMBT1 USH2A SLC38A8

1.57e-04175694eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Paneth|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXB9 CAPS FAM117B SLC14A2

1.64e-041776943743a7d69db9ac4cad70eb531f7075849f34f16b
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC16 MUC5B RIMS1 CHRM3

1.64e-04177694a4c001a8e44142babf9f24dfe6f7b73a70b11b16
ToppCellFetal_29-31_weeks-Epithelial-lung_goblet_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC16 MUC5B RIMS1 CHRM3

1.64e-04177694363e07b0f347f3716d530a28ead854b98e27d37c
ToppCell(5)_Glands_mucous|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC16 MUC5B DMBT1 CHRM3

1.68e-04178694f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

TBX19 KMT2C KCNJ5-AS1 RUSC2

1.68e-04178694536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INAVA RIMS1 UBALD1 CAPN15

1.68e-0417869489f0537459a321ded956bf70ad56fefc0854f8b0
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|390C / Donor, Lineage, Cell class and subclass (all cells)

CAPS MUC16 MUC5B INAVA

1.68e-04178694fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CAPS MUC16 MUC5B INAVA

1.68e-04178694b19c906e067b07eadfd68934d9330b447e24c708
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVC2 KIAA1549 RSBN1L NOTCH3

1.71e-04179694b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellAdult-Epithelial-lung_goblet_cell|Adult / Lineage, Cell type, age group and donor

MUC16 MUC5B INAVA RIMS1

1.71e-041796941fc1f252ca943a2f649d1e627f56acbf15f8e058
ToppCell(5)_Epithelial_cells-(5)_Glands_mucous|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

MUC16 MUC5B DMBT1 CHRM3

1.75e-04180694a4118adaf4b09e2ca01b662ed60e7bbf32a24d58
ToppCellAT1-AT2_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

BNIP5 INAVA MUC3A NOTCH3

1.75e-041806943c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DMBT1 MUC3A NOTCH2 MUC20

1.75e-041806948ba9bba0c9fecf184a4332ba4585fb2439f68cd3
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Dendritic_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INAVA RIMS1 UBALD1 CAPN15

1.75e-04180694710526abedc8e0f9ba19ad69220df4c9468ada8f
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CAPS MUC16 MUC5B DLEC1

1.75e-04180694d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CAPS MUC16 MUC5B MUC20

1.79e-04181694bab282cb0d9fc049f6fb094cf8b1fba104f4ea17
ToppCell10x5'-bone_marrow-Mast-Mast_cell_lympho|bone_marrow / Manually curated celltypes from each tissue

ZNF521 TMEM131 STK11IP IL5RA

1.79e-0418169456fa77ae31f3b7de6e441a439c33a11353b6573a
DiseaseSquamous cell carcinoma of esophagus

KMT2C VENTX DLEC1 NOTCH2 NOTCH3

2.38e-0695665C0279626
Diseasepyridoxate measurement

CACNA1D CHRM3 ABHD16A

4.59e-0531663EFO_0010527
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH2 NOTCH3

1.03e-047662DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH2 NOTCH3

1.03e-047662DOID:3620 (implicated_via_orthology)
Diseasepulmonary fibrosis

MUC5B CHRM3

2.68e-0411662EFO_0009448
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC3A

4.04e-0464663DOID:4947 (is_marker_for)
Diseaseschizophrenia (implicated_via_orthology)

CACNA1D ZNF521 RIMS1

4.83e-0468663DOID:5419 (implicated_via_orthology)
Diseasemosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement

BNIP5 LINC01548 DLEC1 DMD ABHD16A

8.45e-04328665EFO_0008377, EFO_0008378
Diseasenucleus accumbens volume

SP100 USH2A

1.11e-0322662EFO_0006931
DiseaseMammary Carcinoma, Human

FOXM1 HOXB9 LRRC37A LRRC37A2 NOTCH2 NOTCH3

1.14e-03525666C4704874
DiseaseMammary Neoplasms, Human

FOXM1 HOXB9 LRRC37A LRRC37A2 NOTCH2 NOTCH3

1.14e-03525666C1257931
DiseaseMammary Neoplasms

FOXM1 HOXB9 LRRC37A LRRC37A2 NOTCH2 NOTCH3

1.16e-03527666C1458155
Diseasesensory peripheral neuropathy, remission

FOXM1 DLEC1

1.21e-0323662EFO_0009785, MONDO_0002321
Diseasemean fractional anisotropy measurement

DACT1 PROSER3 TMEM131

1.28e-0395663EFO_0008399
DiseaseBreast Carcinoma

FOXM1 HOXB9 LRRC37A LRRC37A2 NOTCH2 NOTCH3

1.29e-03538666C0678222
DiseaseCerebral Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0750935
DiseaseIntracranial Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0750936
DiseasePilocytic Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0334583
DiseaseAstrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0004114
DiseaseJuvenile Pilocytic Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0280783
DiseaseDiffuse Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0280785
DiseaseGrade I Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C1704230
DiseaseSubependymal Giant Cell Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0205768
DiseaseMixed oligoastrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0547065
DiseaseChildhood Cerebral Astrocytoma

KIAA1549 NOTCH2

1.43e-0325662C0338070
Diseasebrain cancer (implicated_via_orthology)

NOTCH2 NOTCH3

1.55e-0326662DOID:1319 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

KIAA1549 NOTCH2

1.55e-0326662C0334581
DiseaseProtoplasmic astrocytoma

KIAA1549 NOTCH2

1.55e-0326662C0334580
DiseaseFibrillary Astrocytoma

KIAA1549 NOTCH2

1.55e-0326662C0334582
DiseaseAnaplastic astrocytoma

KIAA1549 NOTCH2

1.67e-0327662C0334579
Diseaselysophosphatidylcholine 18:2 measurement

NFIB RIMS1

1.79e-0328662EFO_0010361
Diseasebipolar disorder

UBAP2 KDM3B TMEM131 DLEC1 RIMS1 CHRM3

1.83e-03577666MONDO_0004985
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH2 NOTCH3

2.06e-0330662DOID:9256 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
LPSHVWSSTLPAGSS

COL17A1

216

Q9UMD9
LSASAAWGHPSSPPV

CES1

11

P23141
PHASSLWSLFAPSSP

ADAMTSL4

346

Q6UY14
HSPLPSTVHSCSWAP

CAPS

31

Q13938
ETPTAVTAPHSSSWD

ABHD16A

31

O95870
ISSSWIHSPSDAGLP

CHRM3

16

P20309
WPVDSAPASSPQLSH

DMD

3416

P11532
PSPALWDTSSHSTPA

DLX3

211

O60479
AWVPHSTTSPALPVS

MUC5B

1316

Q9HC84
PSPSSPAAGSRTWHE

NFIB

291

O00712
PSRSEVSPWSSFPSD

KIAA1549

711

Q9HCM3
DWTASKGTHSPPLTP

CAPN15

1061

O75808
SSWQAAHSCTPEPPA

MORN1

481

Q5T089
THPAQTSPTVPWTTS

MUC16

10826

Q8WXI7
SPDQWSSSSPHSASD

NOTCH2

2421

Q04721
HSASDWSDVTTSPTP

NOTCH2

2431

Q04721
SSPWTPHSAPWTPSL

PLAC4

46

Q8WY50
PHSAPWTPSLTLDTF

PLAC4

51

Q8WY50
HPWNTPQVSSFPSST

LINC01548

71

A6NM66
SPWDVSGLPILSSSH

MDN1

3081

Q9NU22
AWSTHNTVSPPSWSP

KMT2C

846

Q8NEZ4
SNPLGPPDSWSSHSS

LRRC37A2

51

A6NM11
SNPLGPPESWSSHSS

LRRC37A

51

A6NMS7
SASSDGPHPVITPSW

MUC20

386

Q8N307
TPQTSAWLPPTSAEH

CHUK

676

O15111
VLSAHLSSTTSPPWT

KCNJ5-AS1

6

Q8TAV5
LSSTTSPPWTHAAIS

KCNJ5-AS1

11

Q8TAV5
SSSPYVSPRHSPWSS

LMOD2

386

Q6P5Q4
NLWASDSPDPVHSTP

C9orf131

506

Q5VYM1
TTETPLHSTPGLTSW

MUC3A

2381

Q02505
SSPLSPNWVSPSDHQ

FAM205BP

221

Q63HN1
ASPSPPSLSDWSEST

NOTCH3

2256

Q9UM47
PSLSDWSESTPSPAT

NOTCH3

2261

Q9UM47
SSATRHLWLSSSPPD

KIF24

1106

Q5T7B8
APSWPESHSSADSAS

KDM3B

671

Q7LBC6
IPLSTSAASSGPWAH

EVC2

111

Q86UK5
SLSLSTHWAEPKSPG

LCT

1121

P09848
ETSPISSHPVTWQPS

RIMS1

576

Q86UR5
ASWAPLSPHASGSLP

HOXB9

61

P17482
SSWASAELHAPPGSP

IL5RA

111

Q01344
TTSDWARHSDSPAPS

BNIP5

51

P0C671
PSPSSLWSASHPSSS

DACT1

321

Q9NYF0
PPSARSSPHSPWSAA

CACNA1G

1086

O43497
SSPSSSPTHLWTGEV

FAM117B

151

Q6P1L5
TPASASPSWGSHSTP

ATG9B

106

Q674R7
KPSWSSDGSSPASSP

ATG9B

876

Q674R7
RPSSPSTSWHRPASP

MAP7D1

466

Q3KQU3
SSSPSPRDPTDSLDW

MAMSTR

361

Q6ZN01
EWPSPAPSFKEESSH

FOXM1

486

Q08050
LWSPGPSSSSEFSHE

DLEC1

1336

Q9Y238
TPSPDTWPTSHASTA

DMBT1

341

Q9UGM3
TWPTSHASTAGPESS

DMBT1

346

Q9UGM3
ICSAAHSWSTPSPDT

DMBT1

461

Q9UGM3
HSWSTPSPDTLPTIT

DMBT1

466

Q9UGM3
PSPDTWPTSHASTAG

DMBT1

841

Q9UGM3
WPTSHASTAGPESSL

DMBT1

846

Q9UGM3
CSAAHSWSTPSPDTL

DMBT1

961

Q9UGM3
PSPDTWPTSHASTAG

DMBT1

1101

Q9UGM3
SQPTPSPDTWPTSHA

DMBT1

1226

Q9UGM3
SPDTWPTSHASTAGS

DMBT1

1231

Q9UGM3
QPTPSPDTWPTSHAS

DMBT1

1356

Q9UGM3
PDTWPTSHASTAGSE

DMBT1

1361

Q9UGM3
WSSVPESTTDGSPIH

CALCOCO1

66

Q9P1Z2
PRKSSEPWSESSSPA

INAVA

336

Q3KP66
KYSPSHSTRSWATPP

CACNA1D

1971

Q01668
EQPTATESLPPWSHS

RUSC2

806

Q8N2Y8
TESLPPWSHSCPSAV

RUSC2

811

Q8N2Y8
PWSHSCPSAVRPATS

RUSC2

816

Q8N2Y8
WSFAPLSAAPSPSSS

RSBN1L

86

Q6PCB5
PSVWPSALPSLSSDS

REXO1

536

Q8N1G1
SPPQAPSTRDHGSWS

STK11IP

761

Q8N1F8
SSSAINLSWSPPDSP

USH2A

1066

O75445
VDPSEDTSSPHSPEW

TAF1C

766

Q15572
WSPSLPASSDHSTPA

SMG7

986

Q92540
EESWPSSSGTPSLPS

PROSER3

66

Q2NL68
SHPSLSPASWTSVFS

SLC38A8

206

A6NNN8
HPTTTTSWDLKPPTS

UBAP2

401

Q5T6F2
TWPHSVNSSPESPSC

TICRR

1211

Q7Z2Z1
DPTCSWPASSPSSKD

ZNF521

81

Q96K83
WPASSPSSKDQTSPS

ZNF521

86

Q96K83
FRSLTWPPSGSPSHA

SP100

181

P23497
SWPASSGSPTHTATS

TMEM131

1776

Q92545
EPSCSSLWTSHVPAS

WDR25

111

Q64LD2
GPDSWTSLSSTPHAS

TBX19

321

O60806
PSSAGPWANSSLSLH

SIGLEC10

496

Q96LC7
TSPSWPSTSPDTHPA

SLC14A2

26

Q15849
TPHYSTSLWGPPSSS

TNRC6A

1921

Q8NDV7
DWLSQSSCSGPTHTP

VENTX

21

O95231
FPHAATSSSAASSWP

UBALD1

111

Q8TB05
TFHSWPSSKDTRPAP

MUC12

776

Q9UKN1