Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

ABCC3 SETX MYH13 MYO1E DYNC2H1 MYO10 SMC6 RNF213 ABCA9 ZRANB3 ABCC8 DDX39A DNAH5 DDX39B

3.23e-0661410314GO:0140657
GeneOntologyMolecularFunctionbone sialoprotein binding

ANXA2 ANXA2P2

2.64e-0521032GO:0044730
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYH13 MYO1E DYNC2H1 MYO10 MYO18B DNAH5

3.36e-051181036GO:0003774
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 MYO1E DYNC2H1 SMC6 RNF213 ABCA9 ABCC8 DDX39A DNAH5 DDX39B

9.43e-0544110310GO:0016887
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 DOCK3 OBSCN DOCK10 DENND6A ARHGEF2 ARHGEF26

1.96e-042311037GO:0005085
GeneOntologyMolecularFunctionphospholipase A2 inhibitor activity

ANXA2 ANXA2P2

2.61e-0451032GO:0019834
GeneOntologyMolecularFunctionubiquitin-like protein-specific endopeptidase activity

SENP6 SENP5

2.61e-0451032GO:0070137
GeneOntologyMolecularFunctionSUMO-specific endopeptidase activity

SENP6 SENP5

2.61e-0451032GO:0070139
GeneOntologyMolecularFunctioncalcium-dependent protein serine/threonine phosphatase regulator activity

RCAN3 RCAN2

2.61e-0451032GO:0008597
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK1 DOCK3 TBC1D7 OBSCN DOCK10 ARHGAP11A DENND6A ARHGEF2 ARHGEF26 ARHGAP11B

2.91e-0450710310GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK1 DOCK3 TBC1D7 OBSCN DOCK10 ARHGAP11A DENND6A ARHGEF2 ARHGEF26 ARHGAP11B

2.91e-0450710310GO:0030695
GeneOntologyMolecularFunctionchitinase activity

CHIA CHIT1

3.90e-0461032GO:0004568
GeneOntologyMolecularFunctionchitin binding

CHIA CHIT1

7.23e-0481032GO:0008061
GeneOntologyMolecularFunctionmicrofilament motor activity

MYH13 MYO1E MYO10

9.86e-04381033GO:0000146
GeneOntologyMolecularFunctionchloride channel activity

GABRB1 GABRB3 CLCA3P CLCA2

1.03e-03861034GO:0005254
GeneOntologyMolecularFunctioncalmodulin binding

MYH13 MYO1E MYO10 OBSCN SLC8A2 ASPM

1.23e-032301036GO:0005516
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK1 DOCK3 ANXA2 ANXA2P2 TBC1D7 DOCK10 ARHGEF2

1.38e-033211037GO:0031267
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

GABRB1 GABRB3 ABCC3 CLCA3P CLCA2

1.93e-031711035GO:0015103
GeneOntologyMolecularFunctioninsulin-like growth factor I binding

INSR LRP2

1.98e-03131032GO:0031994
GeneOntologyMolecularFunctionG protein-coupled neurotransmitter receptor activity

GABRB1 HRH3

1.98e-03131032GO:0099528
GeneOntologyMolecularFunctionphospholipase inhibitor activity

ANXA2 ANXA2P2

1.98e-03131032GO:0004859
GeneOntologyMolecularFunctionmonoatomic anion channel activity

GABRB1 GABRB3 CLCA3P CLCA2

2.00e-031031034GO:0005253
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC3 ABCA9 ABCC8

2.07e-03491033GO:0140359
GeneOntologyMolecularFunctionligand-gated monoatomic anion channel activity

GABRB1 GABRB3 CLCA2

2.19e-03501033GO:0099095
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

KDM4C JMJD1C

2.30e-03141032GO:0032454
GeneOntologyMolecularFunctionenzyme regulator activity

DOCK1 DOCK3 ANXA2 ANXA2P2 TBC1D7 OBSCN DOCK10 ARHGAP11A RCAN3 DENND6A PPP2R5E UMODL1 ARHGEF2 ARHGEF26 ARHGAP11B RCAN2

2.42e-03141810316GO:0030234
GeneOntologyMolecularFunctionGTPase binding

DOCK1 DOCK3 ANXA2 ANXA2P2 TBC1D7 DOCK10 ARHGEF2

2.63e-033601037GO:0051020
GeneOntologyMolecularFunctioninsulin receptor substrate binding

INSR JAK2

2.65e-03151032GO:0043560
GeneOntologyMolecularFunctionS100 protein binding

ANXA2 ANXA2P2

2.65e-03151032GO:0044548
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GABRB1 GABRB3 CLCA2 ABCC8 KCNJ16

3.26e-031931035GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GABRB1 GABRB3 CLCA2 ABCC8 KCNJ16

3.56e-031971035GO:0022834
GeneOntologyMolecularFunctionGABA-gated chloride ion channel activity

GABRB1 GABRB3

3.82e-03181032GO:0022851
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DNAH5

3.82e-03181032GO:0008569
GeneOntologyMolecularFunctionlipase inhibitor activity

ANXA2 ANXA2P2

3.82e-03181032GO:0055102
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

GABRB1 GABRB3 CLCA3P CLCA2

4.02e-031251034GO:0015108
GeneOntologyMolecularFunctioninsulin-like growth factor binding

INSR LRP2

4.26e-03191032GO:0005520
GeneOntologyMolecularFunctionGABA-A receptor activity

GABRB1 GABRB3

4.26e-03191032GO:0004890
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

UBR2 RNF213 TRIM77 FBXO2 AREL1 RNF128 PML

4.57e-033981037GO:0061659
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

2.47e-0521032GO:1905597
GeneOntologyBiologicalProcessprotein sumoylation

SMC6 AHRR SENP6 PML SENP5

2.82e-05711035GO:0016925
GeneOntologyBiologicalProcesspositive regulation of receptor-mediated endocytosis involved in cholesterol transport

ANXA2 ANXA2P2

7.38e-0531032GO:1905602
GeneOntologyBiologicalProcessnegative regulation of low-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

7.38e-0531032GO:0032804
GeneOntologyBiologicalProcesstransport across blood-brain barrier

ABCC3 INSR SLC7A2 SLC8A2 LRP2

7.52e-05871035GO:0150104
GeneOntologyBiologicalProcessvascular transport

ABCC3 INSR SLC7A2 SLC8A2 LRP2

7.94e-05881035GO:0010232
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein particle clearance

ANXA2 ANXA2P2

1.47e-0441032GO:1905581
GeneOntologyBiologicalProcessnegative regulation of receptor catabolic process

ANXA2 ANXA2P2

1.47e-0441032GO:2000645
GeneOntologyBiologicalProcesspolysaccharide digestion

CHIA CHIT1

1.47e-0441032GO:0044245
GeneOntologyBiologicalProcesspositive regulation of intracellular cholesterol transport

ANXA2 ANXA2P2

1.47e-0441032GO:0032385
GeneOntologyBiologicalProcesspositive regulation of intracellular sterol transport

ANXA2 ANXA2P2

1.47e-0441032GO:0032382
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle clearance

ANXA2 ANXA2P2 ABCC8

2.27e-04241033GO:0010988
GeneOntologyBiologicalProcesspositive regulation of plasma membrane repair

ANXA2 ANXA2P2

2.45e-0451032GO:1905686
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor binding

ANXA2 ANXA2P2

2.45e-0451032GO:1905595
GeneOntologyBiologicalProcesspositive regulation of intracellular lipid transport

ANXA2 ANXA2P2

2.45e-0451032GO:0032379
GeneOntologyBiologicalProcesspost-translational protein modification

UBR2 DET1 TBC1D7 SMC6 HLCS RNF213 TRIM77 FBXO2 JAK2 AREL1 AHRR SENP6 RNF128 PML SENP5

2.81e-04107410315GO:0043687
GeneOntologyBiologicalProcessmemory

GABRB3 INSR SLC8A2 ABCC8 RCAN2 HRH3

3.15e-041831036GO:0007613
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

AP5Z1 LRP2 RNF128

3.62e-04281033GO:0007039
GeneOntologyBiologicalProcesspositive regulation of low-density lipoprotein receptor activity

ANXA2 ANXA2P2

3.66e-0461032GO:1905599
GeneOntologyBiologicalProcesschitin catabolic process

CHIA CHIT1

3.66e-0461032GO:0006032
GeneOntologyBiologicalProcesschitin metabolic process

CHIA CHIT1

3.66e-0461032GO:0006030
GeneOntologyBiologicalProcessprotein modification by small protein conjugation

UBR2 DET1 TBC1D7 SMC6 RNF213 TRIM77 FBXO2 AREL1 AHRR SENP6 RNF128 PML SENP5

5.01e-0489310313GO:0032446
GeneOntologyBiologicalProcesspost-embryonic hemopoiesis

MYO1E JAK2

5.10e-0471032GO:0035166
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP2 RNF128

5.10e-0471032GO:1904352
GeneOntologyBiologicalProcesscellular response to histamine

GABRB1 GABRB3

5.10e-0471032GO:0071420
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

5.10e-0471032GO:0032803
GeneOntologyBiologicalProcesslow-density lipoprotein particle receptor catabolic process

ANXA2 ANXA2P2

5.10e-0471032GO:0032802
GeneOntologyBiologicalProcesslow-density lipoprotein receptor particle metabolic process

ANXA2 ANXA2P2

5.10e-0471032GO:0032799
GeneOntologyCellularComponentsarcolemma

ANXA2 ANXA2P2 OBSCN SLC8A2 ABCC8 DLG1 UTRN

4.64e-051901047GO:0042383
GeneOntologyCellularComponentAnxA2-p11 complex

ANXA2 ANXA2P2

7.33e-0531042GO:1990665
GeneOntologyCellularComponentPCSK9-AnxA2 complex

ANXA2 ANXA2P2

7.33e-0531042GO:1990667
GeneOntologyCellularComponentmyosin complex

MYH13 MYO1E MYO10 MYO18B

2.13e-04591044GO:0016459
GeneOntologyCellularComponentmyosin filament

MYH13 OBSCN MYO18B

2.54e-04251043GO:0032982
GeneOntologyCellularComponentbasal plasma membrane

ABCC3 ANXA2 ANXA2P2 SLC8A2 SLC16A5 CLCA2 KCNJ16 DLG1

3.92e-043541048GO:0009925
GeneOntologyCellularComponentmyelin sheath adaxonal region

ANXA2 ANXA2P2

5.07e-0471042GO:0035749
GeneOntologyCellularComponentbasal part of cell

ABCC3 ANXA2 ANXA2P2 SLC8A2 SLC16A5 CLCA2 KCNJ16 DLG1

6.04e-043781048GO:0045178
GeneOntologyCellularComponentnuclear matrix

ANXA2 ANXA2P2 HLCS DDX39B PML

6.78e-041401045GO:0016363
GeneOntologyCellularComponentbasolateral plasma membrane

ABCC3 ANXA2 ANXA2P2 SLC8A2 SLC16A5 KCNJ16 DLG1

1.10e-033201047GO:0016323
GeneOntologyCellularComponentpinosome

ANXA2 ANXA2P2

1.31e-03111042GO:0044352
GeneOntologyCellularComponentmacropinosome

ANXA2 ANXA2P2

1.31e-03111042GO:0044354
GeneOntologyCellularComponentpostsynapse

GABRB1 DOCK1 GABRB3 DOCK10 FBXO2 JAK2 SLC8A2 SENP6 DLG1 ARHGEF2 UTRN CDH10 SENP5

1.61e-03101810413GO:0098794
GeneOntologyCellularComponentnuclear periphery

ANXA2 ANXA2P2 HLCS DDX39B PML

1.65e-031711045GO:0034399
GeneOntologyCellularComponentplasma membrane protein complex

GJD2 BTBD8 ANXA2 ANXA2P2 INSR JAK2 ABCC8 KCNJ16 DLG1 UTRN CDH10

1.82e-0378510411GO:0098797
DomainP-loop_NTPase

ABCC3 SETX MYH13 MYO1E DYNC2H1 MYO10 SMC6 RNF213 KTI12 ABCA9 ZRANB3 ABCC8 ASPM DLG1 MYO18B DDX39A DNAH5 DDX39B

6.98e-0784810218IPR027417
DomainIQ

MYH13 MYO1E MYO10 OBSCN ASPM MYO18B

2.46e-06711026PF00612
DomainIQ_motif_EF-hand-BS

MYH13 MYO1E MYO10 OBSCN ASPM MYO18B

9.83e-06901026IPR000048
DomainIQ

MYH13 MYO1E MYO10 OBSCN ASPM MYO18B

1.19e-05931026PS50096
DomainDOCK_C

DOCK1 DOCK3 DOCK10

2.53e-05111023IPR010703
DomainDHR-1_domain

DOCK1 DOCK3 DOCK10

2.53e-05111023IPR027007
DomainDHR_2

DOCK1 DOCK3 DOCK10

2.53e-05111023PS51651
DomainDHR_1

DOCK1 DOCK3 DOCK10

2.53e-05111023PS51650
DomainDOCK-C2

DOCK1 DOCK3 DOCK10

2.53e-05111023PF14429
DomainDHR-2

DOCK1 DOCK3 DOCK10

2.53e-05111023IPR027357
DomainDHR-2

DOCK1 DOCK3 DOCK10

2.53e-05111023PF06920
DomainDOCK

DOCK1 DOCK3 DOCK10

2.53e-05111023IPR026791
DomainCBM_14

CHIA CHIT1

2.95e-0521022PF01607
DomainChitin-bd_dom

CHIA CHIT1

2.95e-0521022IPR002557
DomainCHIT_BIND_II

CHIA CHIT1

2.95e-0521022PS50940
Domain-

CHIA CHIT1

2.95e-05210222.170.140.10
DomainChtBD2

CHIA CHIT1

2.95e-0521022SM00494
Domain-

ABCC3 SETX MYO1E DYNC2H1 SMC6 RNF213 KTI12 ABCA9 ZRANB3 ABCC8 DLG1 DDX39A DNAH5 DDX39B

5.33e-05746102143.40.50.300
DomainMyosin_head_motor_dom

MYH13 MYO1E MYO10 MYO18B

5.37e-05381024IPR001609
DomainMYOSIN_MOTOR

MYH13 MYO1E MYO10 MYO18B

5.37e-05381024PS51456
DomainMyosin_head

MYH13 MYO1E MYO10 MYO18B

5.37e-05381024PF00063
DomainMYSc

MYH13 MYO1E MYO10 MYO18B

5.37e-05381024SM00242
DomainIQ

MYH13 MYO10 OBSCN ASPM MYO18B

8.12e-05811025SM00015
DomainGABAAb_rcpt

GABRB1 GABRB3

8.83e-0531022IPR002289
DomainCalcipressin

RCAN3 RCAN2

8.83e-0531022PF04847
DomainCalcipressin

RCAN3 RCAN2

8.83e-0531022IPR006931
DomainAAA+_ATPase

ABCC3 DYNC2H1 RNF213 ABCA9 ABCC8 DNAH5

1.39e-041441026IPR003593
DomainAAA

ABCC3 DYNC2H1 RNF213 ABCA9 ABCC8 DNAH5

1.39e-041441026SM00382
DomainMyosin-like_IQ_dom

MYH13 ASPM MYO18B

1.44e-04191023IPR027401
Domain-

MYH13 ASPM MYO18B

1.44e-041910234.10.270.10
DomainSH3

DOCK1 DOCK3 MYO1E OBSCN SH3TC1 DLG1 ARHGEF26

1.83e-042161027SM00326
DomainSH3

DOCK1 DOCK3 MYO1E OBSCN SH3TC1 DLG1 ARHGEF26

1.83e-042161027PS50002
DomainSH3_domain

DOCK1 DOCK3 MYO1E OBSCN SH3TC1 DLG1 ARHGEF26

2.05e-042201027IPR001452
DomainDOCK_N

DOCK1 DOCK3

2.92e-0451022PF16172
DomainDOCK_N

DOCK1 DOCK3

2.92e-0451022IPR032376
DomainChitinase_insertion

CHIA CHIT1

2.92e-0451022IPR029070
Domain-

CHIA CHIT1

2.92e-04510223.10.50.10
DomainGlyco_hydro_18_chit_AS

CHIA CHIT1

4.37e-0461022IPR001579
DomainGlyco_hydro18_cat

CHIA CHIT1

6.09e-0471022IPR001223
DomainPeptidase_C48

SENP6 SENP5

6.09e-0471022PF02902
DomainGlyco_hydro_18

CHIA CHIT1

6.09e-0471022PF00704
DomainChitinase_II

CHIA CHIT1

6.09e-0471022IPR011583
DomainGlyco_18

CHIA CHIT1

6.09e-0471022SM00636
DomainCHITINASE_18

CHIA CHIT1

6.09e-0471022PS01095
DomainULP_PROTEASE

SENP6 SENP5

6.09e-0471022PS50600
DomainPeptidase_C48_C

SENP6 SENP5

6.09e-0471022IPR003653
DomainDHC_N1

DYNC2H1 DNAH5

8.09e-0481022PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH5

8.09e-0481022IPR013594
DomainSPAN-X_fam

SPANXA1 SPANXD

1.29e-03101022IPR010007
DomainSPAN-X

SPANXA1 SPANXD

1.29e-03101022PF07458
DomainTyr_kinase_rcpt_2_CS

INSR ROS1

1.57e-03111022IPR002011
DomainRECEPTOR_TYR_KIN_II

INSR ROS1

1.88e-03121022PS00239
Domainfn3

INSR OBSCN UMODL1 ROS1 IL2RG

1.95e-031621025PF00041
DomainPROTEIN_KINASE_TYR

INSR OBSCN JAK2 ROS1

1.97e-03971024PS00109
DomainTyr_kinase_AS

INSR OBSCN JAK2 ROS1

1.97e-03971024IPR008266
DomainSH3_1

DOCK1 MYO1E SH3TC1 DLG1 ARHGEF26

2.06e-031641025PF00018
DomainELM2

RCOR2 RCOR1

2.22e-03131022PF01448
DomainELM2

RCOR2 RCOR1

2.22e-03131022PS51156
DomainELM2_dom

RCOR2 RCOR1

2.22e-03131022IPR000949
DomainELM2

RCOR2 RCOR1

2.22e-03131022SM01189
DomainABC_tran

ABCC3 ABCA9 ABCC8

2.29e-03481023PF00005
DomainABC_TRANSPORTER_2

ABCC3 ABCA9 ABCC8

2.29e-03481023PS50893
DomainABC_TRANSPORTER_1

ABCC3 ABCA9 ABCC8

2.43e-03491023PS00211
DomainFERM_central

MYO10 FRMPD1 JAK2

2.43e-03491023IPR019748
DomainFERM_domain

MYO10 FRMPD1 JAK2

2.43e-03491023IPR000299
DomainFERM_1

MYO10 FRMPD1 JAK2

2.57e-03501023PS00660
DomainFERM_2

MYO10 FRMPD1 JAK2

2.57e-03501023PS00661
DomainFERM_3

MYO10 FRMPD1 JAK2

2.57e-03501023PS50057
DomainBand_41_domain

MYO10 FRMPD1 JAK2

2.57e-03501023IPR019749
DomainB41

MYO10 FRMPD1 JAK2

2.57e-03501023SM00295
DomainABC_transporter-like

ABCC3 ABCA9 ABCC8

2.57e-03501023IPR003439
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH5

2.57e-03141022IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH5

2.57e-03141022IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH5

2.57e-03141022IPR013602
DomainDHC_N2

DYNC2H1 DNAH5

2.57e-03141022PF08393
DomainMT

DYNC2H1 DNAH5

2.57e-03141022PF12777
DomainAAA_8

DYNC2H1 DNAH5

2.57e-03141022PF12780
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH5

2.57e-03141022IPR011704
DomainAAA_5

DYNC2H1 DNAH5

2.57e-03141022PF07728
DomainDHC_fam

DYNC2H1 DNAH5

2.96e-03151022IPR026983
DomainDynein_heavy_dom

DYNC2H1 DNAH5

2.96e-03151022IPR004273
DomainDynein_heavy

DYNC2H1 DNAH5

2.96e-03151022PF03028
DomainLY

LRP2 ROS1

2.96e-03151022SM00135
DomainLDLR_classB_rpt

LRP2 ROS1

2.96e-03151022IPR000033
DomainGlycoside_hydrolase_SF

CHIA CHIT1 GANAB

3.04e-03531023IPR017853
DomainFN3

INSR OBSCN UMODL1 ROS1 IL2RG

3.47e-031851025SM00060
DomainARM-like

SETX DOCK10 RIPOR3 PPP2R5E AP5Z1 ASPM

3.65e-032701026IPR011989
DomainFN3

INSR OBSCN UMODL1 ROS1 IL2RG

4.72e-031991025PS50853
DomainDH_1

OBSCN ARHGEF2 ARHGEF26

4.95e-03631023PS00741
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

MRPS31 DOCK1 DOCK3 BTBD8 ANXA2 POLR2D DOCK10 ARHGAP11A GANAB PPP2R5E DLG1 ARHGEF2 DDX39A ARHGEF26 UTRN ARHGAP11B

1.90e-089161061632203420
Pubmed

Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.

DYNC2H1 OBSCN RNF213

1.10e-074106326147384
Pubmed

Secretion of Annexin II via activation of insulin receptor and insulin-like growth factor receptor.

ANXA2 ANXA2P2 INSR

1.10e-074106312431980
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SETX RNMT SMC6 FRMPD1 OBSCN ZRANB3 AREL1 RCOR1 PPP2R5E ALDH1L2 NAT10 LRP2 DLG1 DDX39A UTRN PML

1.89e-0710841061611544199
Pubmed

Analysis of a new allele of limb deformity (ld) reveals tissue- and age-specific transcriptional effects of the Ld Global Control Region.

GJD2 ARHGAP11A ARHGAP11B

2.28e-069106317554679
Pubmed

JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML.

JAK2 PML

9.20e-062106233075130
Pubmed

Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49.

DDX39A DDX39B

9.20e-062106216949217
Pubmed

Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis.

CHIA CHIT1

9.20e-062106235122869
Pubmed

Protooncogenic Role of ARHGAP11A and ARHGAP11B in Invasive Ductal Carcinoma: Two Promising Breast Cancer Biomarkers.

ARHGAP11A ARHGAP11B

9.20e-062106238046902
Pubmed

JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation.

JAK2 PML

9.20e-062106225143485
Pubmed

Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function.

GABRB1 GABRB3

9.20e-062106226950270
Pubmed

Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy.

ANXA2 ANXA2P2

9.20e-062106219536308
Pubmed

Annexin A2 modulates radiation-sensitive transcriptional programming and cell fate.

ANXA2 ANXA2P2

9.20e-062106223148505
Pubmed

The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem.

RCOR1 PML

9.20e-062106218945770
Pubmed

Binding of the human cytomegalovirus (HCMV) tegument protein UL69 to UAP56/URH49 is not required for efficient replication of HCMV.

DDX39A DDX39B

9.20e-062106220610707
Pubmed

ANXA2 (annexin A2) is crucial to ATG7-mediated autophagy, leading to tumor aggressiveness in triple-negative breast cancer cells.

ANXA2 ANXA2P2

9.20e-062106238290972
Pubmed

The cDNA sequence for the protein-tyrosine kinase substrate p36 (calpactin I heavy chain) reveals a multidomain protein with internal repeats.

ANXA2 ANXA2P2

9.20e-06210623013423
Pubmed

Activation of Annexin A2 signaling at the blood-brain barrier in a mouse model of multiple sclerosis.

ANXA2 ANXA2P2

9.20e-062106235064931
Pubmed

Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes.

DDX39A DDX39B

9.20e-062106238225262
Pubmed

Complex Roles of Annexin A2 in Host Blood-Brain Barrier Invasion by Cryptococcus neoformans.

ANXA2 ANXA2P2

9.20e-062106228130864
Pubmed

Cytosolic protein tyrosine phosphatase-epsilon is a negative regulator of insulin signaling in skeletal muscle.

INSR PTPRE

9.20e-062106218006633
Pubmed

Localization of annexin II in the paranodal regions and Schmidt-Lanterman incisures in the peripheral nervous system.

ANXA2 ANXA2P2

9.20e-062106217549680
Pubmed

Annexin A2 promotes proliferative vitreoretinopathy in response to a macrophage inflammatory signal in mice.

ANXA2 ANXA2P2

9.20e-062106239384746
Pubmed

Clustering of the human CLCA gene family on the short arm of chromosome 1 (1p22-31).

CLCA3P CLCA2

9.20e-062106210584316
Pubmed

Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.

ANXA2 ANXA2P2

9.20e-062106220826156
Pubmed

Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue.

ANXA2 ANXA2P2

9.20e-062106227468426
Pubmed

Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.

ANXA2 ANXA2P2

9.20e-062106219841537
Pubmed

Chitinolytic activity in nasal polyps.

CHIA CHIT1

9.20e-062106221711963
Pubmed

Annexin A2 Modulates ROS and Impacts Inflammatory Response via IL-17 Signaling in Polymicrobial Sepsis Mice.

ANXA2 ANXA2P2

9.20e-062106227389701
Pubmed

Annexin II expressed by osteoblasts and endothelial cells regulates stem cell adhesion, homing, and engraftment following transplantation.

ANXA2 ANXA2P2

9.20e-062106217360942
Pubmed

Annexin A2 regulates phagocytosis of photoreceptor outer segments in the mouse retina.

ANXA2 ANXA2P2

9.20e-062106219587120
Pubmed

Annexin A2 at the interface between F-actin and membranes enriched in phosphatidylinositol 4,5,-bisphosphate.

ANXA2 ANXA2P2

9.20e-062106219022301
Pubmed

HIV-1 infection of microglial cells in a reconstituted humanized mouse model and identification of compounds that selectively reverse HIV latency.

RCOR2 RCOR1

9.20e-062106229256041
Pubmed

Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury.

ANXA2 ANXA2P2

9.20e-062106238253182
Pubmed

Parsing the roles of DExD-box proteins DDX39A and DDX39B in alternative RNA splicing.

DDX39A DDX39B

9.20e-062106238801080
Pubmed

Annexin A2 is a novel cellular redox regulatory protein involved in tumorigenesis.

ANXA2 ANXA2P2

9.20e-062106222185818
Pubmed

Increased expression of acidic mammalian chitinase and chitotriosidase in the nasal mucosa of patients with allergic rhinitis.

CHIA CHIT1

9.20e-062106220422678
Pubmed

A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification.

ARHGAP11A ARHGAP11B

9.20e-062106227957544
Pubmed

Receptor-type protein tyrosine phosphatase epsilon (PTPepsilonM) is a negative regulator of insulin signaling in primary hepatocytes and liver.

INSR PTPRE

9.20e-062106215738637
Pubmed

GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.

GABRB1 GABRB3

9.20e-062106221735059
Pubmed

A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events.

ANXA2 ANXA2P2

9.20e-062106221486955
Pubmed

Terminal regions of UAP56 and URH49 are required for their distinct complex formation functioning to an essential role in mRNA processing and export.

DDX39A DDX39B

9.20e-062106238377942
Pubmed

Lipid raft endocytosis and exosomal transport facilitate extracellular trafficking of annexin A2.

ANXA2 ANXA2P2

9.20e-062106221737841
Pubmed

Multiple modes for conferring surface expression of homomeric beta1 GABAA receptors.

GABRB1 GABRB3

9.20e-062106218650446
Pubmed

Regulation of the low-dose radiation paracrine-specific anchorage-independent growth response by annexin A2.

ANXA2 ANXA2P2

9.20e-062106219580511
Pubmed

Evaluation of AMCase and CHIT-1 expression in monocyte macrophages lineage.

CHIA CHIT1

9.20e-062106223129258
Pubmed

Selenomethionine promotes ANXA2 phosphorylation for proliferation and protein synthesis of myoblasts and skeletal muscle growth.

ANXA2 ANXA2P2

9.20e-062106236739096
Pubmed

Methionine-induced hyperhomocysteinemia reverts fibrinolytic pathway activation in a murine model of acute promyelocytic leukemia.

ANXA2 ANXA2P2

9.20e-062106222517898
Pubmed

Anxa2 gene silencing attenuates obesity-induced insulin resistance by suppressing the NF-κB signaling pathway.

ANXA2 ANXA2P2

9.20e-062106230462534
Pubmed

Identification of a novel acidic mammalian chitinase distinct from chitotriosidase.

CHIA CHIT1

9.20e-062106211085997
Pubmed

Inhibition of the membrane repair protein annexin-A2 prevents tumor invasion and metastasis.

ANXA2 ANXA2P2

9.20e-062106238092984
Pubmed

Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.

ANXA2 ANXA2P2

9.20e-062106221572519
Pubmed

Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice.

ANXA2 ANXA2P2

9.20e-062106221788340
Pubmed

The Membrane Phospholipid Binding Protein Annexin A2 Promotes Phagocytosis and Nonlytic Exocytosis of Cryptococcus neoformans and Impacts Survival in Fungal Infection.

ANXA2 ANXA2P2

9.20e-062106227371724
Pubmed

Ischemia/reperfusion-induced MiD51 upregulation recruits Drp1 to mitochondria and contributes to myocardial injury.

MIEF1 UTRN

9.20e-062106237149986
Pubmed

Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice.

ANXA2 ANXA2P2

9.20e-062106231817350
Pubmed

ANNEXIN A2 FACILITATES NEOVASCULARIZATION TO PROTECT AGAINST MYOCARDIAL INFARCTION INJURY VIA INTERACTING WITH MACROPHAGE YAP AND ENDOTHELIAL INTEGRIN Β3.

ANXA2 ANXA2P2

9.20e-062106237832154
Pubmed

Localization of Dlg at the mammalian neuromuscular junction.

DLG1 UTRN

9.20e-06210629674605
Pubmed

Genetic association between human chitinases and lung function in COPD.

CHIA CHIT1

9.20e-062106222200767
Pubmed

Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.

ANXA2 ANXA2P2

9.20e-062106230902828
Pubmed

The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression.

DDX39A DDX39B

9.20e-062106220573985
Pubmed

Cell surface translocation of annexin A2 facilitates glutamate-induced extracellular proteolysis.

ANXA2 ANXA2P2

9.20e-062106224742684
Pubmed

Annexin A2 depletion exacerbates the intracerebral microhemorrhage induced by acute rickettsia and Ebola virus infections.

ANXA2 ANXA2P2

9.20e-062106232687500
Pubmed

Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.

ANXA2 ANXA2P2

9.20e-062106222453828
Pubmed

CHIT1 and AMCase expression in human gastric mucosa: correlation with inflammation and Helicobacter pylori infection.

CHIA CHIT1

9.20e-062106219242357
Pubmed

Agents that bind annexin A2 suppress ocular neovascularization.

ANXA2 ANXA2P2

9.20e-062106220607799
Pubmed

ArhGAP11A mediates amyloid-β generation and neuropathology in an Alzheimer's disease-like mouse model.

ARHGAP11A ARHGAP11B

9.20e-062106237302068
Pubmed

A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.

ANXA2 ANXA2P2

9.20e-062106231253864
Pubmed

Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo.

ANXA2 ANXA2P2

9.20e-062106219628708
Pubmed

Annexin A2 binds to the localization signal in the 3' untranslated region of c-myc mRNA.

ANXA2 ANXA2P2

9.20e-062106215654879
Pubmed

Anti-dsDNA antibodies bind to mesangial annexin II in lupus nephritis.

ANXA2 ANXA2P2

9.20e-062106220847146
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK1 DOCK3 DOCK10

9.77e-0614106312432077
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 UBR2 SPTLC3 INSR FRMPD1 OBSCN RNF213 JMJD1C JAK2 PTPRE SH3TC1 ABCC8 NAT10 DLG1 ARHGEF26 UTRN

1.14e-0514891061628611215
Pubmed

Pals1 is a major regulator of the epithelial-like polarization and the extension of the myelin sheath in peripheral nerves.

ANXA2 ANXA2P2 DLG1

1.22e-0515106320237282
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MRPS31 SETX OBSCN RNF213 ARHGAP11A RCAN3 JAK2 DENND6A CEP95 LRP2 UTRN

1.59e-057361061129676528
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

SETX WDR36 SMC6 RNF213 NAT10 SENP6 PML

1.64e-05262106736880596
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

ABCC3 INSR SLC7A2 SLC8A2 LRP2

1.81e-05105106530280653
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MRPS31 SETX WDR36 MYH13 INSR SMC6 RNF213 DENND6A NDC1 MIEF1 DLG1

2.61e-057771061135844135
Pubmed

STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.

ANXA2 ANXA2P2

2.76e-053106235098646
Pubmed

The Annexin A2-Notch regulatory loop in hepatocytes promotes liver fibrosis in NAFLD by increasing osteopontin expression.

ANXA2 ANXA2P2

2.76e-053106235413401
Pubmed

Jmjd1c is dispensable for healthy adult hematopoiesis and Jak2V617F-driven myeloproliferative disease initiation in mice.

JMJD1C JAK2

2.76e-053106232017785
Pubmed

Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations.

CHIA CHIT1

2.76e-053106220538957
Pubmed

The histone demethylase JMJD2C constitutes a novel NFE2 target gene that is required for the survival of JAK2V617F mutated cells.

KDM4C JAK2

2.76e-053106236709354
Pubmed

Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases.

ANXA2 ANXA2P2

2.76e-053106228694388
Pubmed

High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2.

ANXA2 ANXA2P2

2.76e-053106227470587
Pubmed

Annexins--unique membrane binding proteins with diverse functions.

ANXA2 ANXA2P2

2.76e-053106215169834
Pubmed

Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).

RCOR2 RCOR1

2.76e-053106221876670
Pubmed

Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.

ANXA2 ANXA2P2

2.76e-053106224808179
Pubmed

The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.

CHIA CHIT1

2.76e-053106219644363
Pubmed

The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway.

ANXA2 ANXA2P2

2.76e-053106226963384
Pubmed

Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle.

ANXA2 ANXA2P2

2.76e-053106228334824
Pubmed

A distinct molecular mutational profile and its clinical impact in essential thrombocythemia and primary myelofibrosis patients.

JAK2 PML

2.76e-053106232164591
Pubmed

Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.

ANXA2 ANXA2P2

2.76e-053106222223826
Pubmed

Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56.

DDX39A DDX39B

2.76e-053106215047853
Pubmed

Annexin A2 interacting with ELMO1 regulates HCC chemotaxis and metastasis.

DOCK1 ANXA2

2.76e-053106230853625
Pubmed

Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche.

ANXA2 ANXA2P2

2.76e-053106221108988
Pubmed

Inhibition of RAC1-GEF DOCK3 by miR-512-3p contributes to suppression of metastasis in non-small cell lung cancer.

DOCK3 ARHGEF2

2.76e-053106225687035
Pubmed

GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.

GABRB1 GABRB3

2.76e-05310627893750
Pubmed

Polymorphisms of chitinases are not associated with asthma.

CHIA CHIT1

2.76e-053106220226308
Pubmed

FOXQ1 promotes the osteogenic differentiation of bone mesenchymal stem cells via Wnt/β-catenin signaling by binding with ANXA2.

ANXA2 ANXA2P2

2.76e-053106232943107
InteractionGK5 interactions

ANXA2 ROS1 DDX39A

7.55e-0681053int:GK5
GeneFamilyChloride channel accessory

CLCA3P CLCA2

9.86e-054742867
GeneFamilyChitinases

CHIA CHIT1

3.42e-047742816
GeneFamilySUMO specific peptidases

SENP6 SENP5

3.42e-047742984
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO10 FRMPD1 JAK2

1.12e-03507431293
GeneFamilyATP binding cassette subfamily C

ABCC3 ABCC8

1.25e-0313742807
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

OBSCN ARHGEF2 ARHGEF26

2.50e-0366743722
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRB1 GABRB3

2.70e-0319742563
GeneFamilyFibronectin type III domain containing

INSR OBSCN ROS1 IL2RG

4.20e-03160744555
GeneFamilyPHD finger proteins|Lysine demethylases

KDM4C JMJD1C

4.30e-0324742485
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_100

RNF213 SLC7A2 CLCA2 SULF1 CDH10 TMEM255A

1.39e-06731026gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_100
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_100

RNF213 SLC7A2 CLCA2 SULF1 CDH10 TMEM255A

2.76e-06821026gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_100
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_500

GABRB1 DOCK1 SPTLC3 NPY2R GJD2 MYO10 INSR CLCA2 SULF1 CDH10

3.20e-0541610210gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_200

GABRB1 RNF213 SLC7A2 CLCA2 SULF1 TMEM255A

9.32e-051521026gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_200
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_top-relative-expression-ranked_1000

TSPAN12 SPTLC3 RNMT DYNC2H1 ARHGAP11A ZRANB3 JAK2 KCNJ16 LRP2 ROS1 DDX39A RNF128 TMEM255A

1.01e-0478710213gudmap_kidney_e10.5_UretericTip_HoxB7_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

GABRB1 TSPAN12 RNF213 SLC7A2 CLCA2 SULF1 RNF128 CDH10 TMEM255A

1.06e-043881029gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_200

GABRB1 RNF213 CLCA2 SULF1 RNF128 TMEM255A

1.15e-041581026gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_200
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_200

RNF213 SLC7A2 CLCA2 SULF1 CDH10 TMEM255A

1.28e-041611026gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_200
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_200

RNF213 SLC7A2 SULF1 RNF128

1.32e-04541024gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_200
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_200

RNF213 SLC7A2 CLCA2 SULF1 CDH10 TMEM255A

1.32e-041621026gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000

GABRB1 DOCK1 GABRB3 SPTLC3 NPY2R SETX GJD2 INSR CLCA2 SULF1 ALDH1L2 ASPM CDH10

1.48e-0481810213DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_200

GABRB1 DOCK1 SPTLC3 CLCA2 SULF1 CDH10

1.51e-041661026gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_200
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500

GABRB1 RNF213 SLC7A2 SULF1 RNF128 CDH10

1.61e-041681026gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_k2_500
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100

SPTLC3 ABCC3 CLCA2

1.78e-04231023gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k3
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_100

RNF213 SLC7A2 SULF1

1.78e-04231023gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_100
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

TSPAN12 DOCK10 RNF213 SLC7A2 CLCA2 SULF1 RNF128 CDH10 TMEM255A

1.86e-044181029gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_500

GABRB1 DOCK1 SPTLC3 SETX INSR CLCA2 SULF1 ASPM SENP5

1.96e-044211029gudmap_developingLowerUrinaryTract_e14.5_ bladder_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

TSPAN12 DOCK10 RNF213 SLC7A2 CLCA2 SULF1 RNF128 CDH10 TMEM255A

2.03e-044231029gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_200

SPTLC3 NPY2R SETX GJD2 CLCA2 CDH10

2.21e-041781026DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_200
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_100

RNF213 SLC7A2 SULF1

2.29e-04251023gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_100
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_100

RNF213 SLC7A2 CLCA2 SULF1

4.02e-04721024gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_100
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 DOCK3 SPTLC3 ABCC3 MYO1E KCNJ16 DNAH5

3.57e-0719110579032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 DOCK3 SPTLC3 ABCC3 MYO1E KCNJ16 DNAH5

3.57e-0719110575717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 SPTLC3 ABCC3 MYO1E RNF213 SLC16A5 DNAH5

4.10e-071951057938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 SPTLC3 ABCC3 MYO1E RNF213 SLC16A5 DNAH5

4.10e-071951057d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UBR2 SETX RNMT RNF213 JMJD1C JAK2 UTRN

4.86e-07200105712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZRANB3 SLC7A2 ABCC8 KCNJ16 MYO18B ARHGEF26

1.77e-0615410565ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MYO1E ANXA2 RCOR1 SLC16A5 DNAH5

5.44e-06187105687b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MYO1E ANXA2 RCOR1 SLC16A5 DNAH5

5.44e-06187105642a1267bfc27b4460b8409ada580a87c4385841c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK3 MYO1E ANXA2 RCOR1 SLC16A5 DNAH5

5.44e-06187105664afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

UBR2 WDR36 DOCK10 RNF213 NDC1 ARHGAP11B

6.14e-0619110569454f642c3621370fa23640b631301346b300950
ToppCellwk_15-18-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP11A RCAN3 ASPM DDX39A IL2RG ARHGAP11B

6.52e-061931056bec113472c40c0106a9427248cbcf54548797596
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 UBR2 KDM4C HLCS DLG1 UTRN

7.77e-06199105694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

DOCK3 CHIA OBSCN MYO18B RCAN2

1.05e-0512210551cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MYO10 SLC7A2 KCNJ16 LRP2 ROS1

2.94e-051511055f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCellnormal_Lung-Endothelial_cells-Tumor_ECs|Endothelial_cells / Location, Cell class and cell subclass

MYO1E INSR SH3TC1 ASPM RCAN2

3.23e-051541055afdc385397c7b13c9348eeef95f109f2363057ae
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Col15a1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ANXA2 RIPOR3 ABCA9 SLC7A2 SRPX2

3.76e-05159105534c90711c5857cf6ada7b3acff99f1d48c7caf29
ToppCell(08)_PNEC-(1)_24hpi|(08)_PNEC / shred by cell type and Timepoint

ABCC3 ABCC8 NAT10

4.32e-05291053f1b59a0b6bce5772bfb084f08507cf775e7eae8c
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-B_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK3 KTI12 SLC16A5 IL2RG PML

4.36e-0516410554274a4f225cabf61f0fe27d8ea162b4eba612f87
ToppCellfacs-Trachea-18m-Hematologic-lymphocytic-B_cell-B_cell_of_the_trachea|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK3 KTI12 SLC16A5 IL2RG PML

4.36e-051641055d62143450f59097ad4b34603a6257f897a769ead
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DOCK10 RCAN3 MYO18B ARHGEF26 DDX39B

4.88e-0516810555e721268f0baa51d3f640f7f4c41db769ebef210
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 ABCC3 OBSCN MYO18B RCAN2

5.17e-0517010554232fe937909f93d3736988c707b8f95ce993398
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ALDH1L2 ABCC8 MYO18B RCAN2

5.46e-051721055ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ALDH1L2 ABCC8 MYO18B RCAN2

5.46e-051721055bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA2 ANXA2P2 FRMPD1 SLC7A2 TMEM255A

6.09e-0517610554843af68f013732c28a8b8edad30d5fa0f2b084b
ToppCelldroplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLCS RCAN3 AREL1 UMODL1 KCNJ16

6.09e-0517610558e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

WDR36 RNF213 ARHGAP11A ZRANB3 DDX39B

6.26e-05177105582fdd6185b368f54f03de389427cbe3071d21a99
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

DOCK3 FRMPD1 DOCK10 SH3TC1 RCAN2

6.95e-0518110554a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 OBSCN DLG1 MYO18B RCAN2

7.14e-051821055287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

NPY2R SLC8A2 SULF1 ABCC8 RCAN2

7.14e-051821055354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

NPY2R GJD2 RCAN3 MMEL1 ABCC8

7.14e-05182105504ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellwk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GABRB3 FRMPD1 ABCC8 RNF128 CDH10

7.32e-0518310558820cfed27b292bc0bc9cde4005219ed41900552
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTLC3 ABCC3 SLC7A2 SLC16A5 ABCC8

7.32e-0518310557eaa6ef7c6cf848fd6489f97677f4406318da22f
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO2 SLC16A5 UMODL1 ALDH1L2 TMEM255A

7.51e-0518410551e54fd372c6e6a298f427b807c14cc49aaaffe80
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN12 SPTLC3 ABCC3 CLCA2 RNF128

7.51e-051841055382b1e90b3f437af596750669c0465a169d97095
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

GABRB1 DOCK3 OBSCN MYO18B RCAN2

7.51e-051841055e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

UBR2 WDR36 DOCK10 RNF213 NDC1

7.71e-051851055a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ANXA2 RNF213 SLC16A5 B4GALNT2 ROS1

7.71e-051851055a6874dd3030d04380cc3c01de1069461aad4ef45
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

UBR2 WDR36 DOCK10 RNF213 NDC1

7.91e-0518610558571956890fc9894d766ba294a28e376b4aba428
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

INSR RIPOR3 ABCA9 SLC7A2 SULF1

8.11e-05187105576bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DOCK10 RNF213 JMJD1C RCOR1 UTRN

8.32e-051881055ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MYO1E RNF213 SLC16A5 DNAH5

8.53e-051891055aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

MYO1E DOCK10 SULF1 ARHGEF26 RCAN2

8.53e-0518910556b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MYO1E RNF213 SLC16A5 DNAH5

8.53e-0518910558977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellAdult|World / Lineage, Cell type, age group and donor

ABCC3 RNF213 PTPRE LRP2 DNAH5

8.53e-0518910555cd285bfad973125d46d704fec18b21266a63379
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

OBSCN JAK2 SLC7A2 MYO18B RCAN2

8.53e-0518910550a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellCOPD-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

INSR DENND6A PTPRE UMODL1 UTRN

8.74e-051901055ed978cd5d9da87b49878a330e362762c487f849f
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

OBSCN JAK2 SLC7A2 MYO18B RCAN2

8.74e-05190105593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 ABCC3 LRP2 DNAH5 CDH10

8.96e-05191105560ff989fe99d243a3d52955223680cdd1f1917a4
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJD2 DYNC2H1 SLC7A2 ABCC8 RCAN2

8.96e-051911055d48e5f67d384226add7d7fb2a124954136e09a82
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GABRB1 FRMPD1 SLC7A2 KCNJ16 ARHGEF26

8.96e-051911055fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellbackground-Cholangiocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

GABRB3 ABCC3 ANXA2 SULF1 KCNJ16

8.96e-05191105599aa8d685767a72bef9f05e7cc8913126a048c39
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ABCC8 MYO18B RNF128 RCAN2

8.96e-05191105597fb4232417a39801e87725755fd16a57c250209
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ABCC8 MYO18B RNF128 RCAN2

8.96e-05191105564070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ABCC8 MYO18B RNF128 RCAN2

9.18e-0519210550bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JAK2 SLC7A2 ABCC8 MYO18B RCAN2

9.18e-051921055bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MYO1E ANXA2 PTPRE SH3TC1

9.18e-0519210558b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JAK2 SLC7A2 ABCC8 MYO18B RCAN2

9.18e-051921055b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK1 MYH13 DYNC2H1 ABCA9 SRPX2

9.18e-05192105560b1312e84f6d6448365a952469c506c00b5fe93
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN ABCC8 MYO18B RNF128 RCAN2

9.18e-051921055d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 DOCK10 SLC7A2 UTRN TMEM255A

9.41e-051931055294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 INSR OBSCN MYO18B RCAN2

9.41e-051931055dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ABCC3 SLC16A5 KCNJ16 DNAH5

9.41e-051931055263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ABCC3 SLC16A5 KCNJ16 DNAH5

9.41e-05193105580e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ABCC3 SLC16A5 KCNJ16 DNAH5

9.41e-051931055b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 DOCK10 SLC7A2 UTRN TMEM255A

9.41e-0519310553d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BTBD8 FRMPD1 DOCK10 UTRN TMEM255A

9.64e-05194105552aebb0b563e2c2058e7f0554ae870e47692b163
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 DOCK10 SLC7A2 UTRN TMEM255A

9.64e-0519410556ac759828c41ffa974ee82842162caa959351dd1
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RNMT HLCS SLC8A2 MYO18B SENP5

9.64e-051941055b111d10c99d7ff7eb261cd7786cd9d9a549049b1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMPD1 DOCK10 SLC7A2 UTRN TMEM255A

9.64e-0519410555d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BTBD8 FRMPD1 DOCK10 UTRN TMEM255A

9.64e-051941055bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR3 ABCA9 SRPX2 SULF1 RCAN2

9.64e-05194105590efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR3 ABCA9 SRPX2 SULF1 RCAN2

9.64e-051941055df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JAK2 SLC7A2 MYO18B UTRN RCAN2

9.64e-0519410555c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JAK2 SLC7A2 MYO18B UTRN RCAN2

9.64e-051941055ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

GABRB1 DOCK3 OBSCN MYO18B RCAN2

9.87e-051951055f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

DOCK3 INSR OBSCN MYO18B RCAN2

9.87e-05195105575fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANXA2 MMEL1 SULF1 LRP2 TMEM255A

9.87e-0519510558a9d05f7a5397836b7dfb8ae4f7c4896042ac0fe
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

RIPOR3 ABCA9 SLC7A2 SRPX2 SULF1

9.87e-0519510553d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR3 ABCA9 SRPX2 SULF1 RCAN2

1.01e-0419610552b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANXA2 MMEL1 SULF1 LRP2 TMEM255A

1.01e-041961055147dc1ca5942df48a083cce39a9a7541430f8365
ToppCelldroplet-Mammary_Gland-nan-18m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ANXA2 SLC7A2 CLCA2 ABCC8

1.01e-04196105500f9171da4c791619e8c4c8c3c7da578c96a30ed
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR3 ABCA9 SRPX2 SULF1 ARHGEF26

1.04e-04197105509946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK10 RNF213 PTPRE SH3TC1 UTRN

1.04e-04197105510190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RNMT KDM4C RNF213 UTRN DDX39B

1.04e-04197105557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR3 ABCA9 SRPX2 SULF1 RCAN2

1.04e-04197105580e153790cef37b743e22a7370ff5b3a6abf147d
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGAP11A NDC1 CLCA2 ASPM ROS1

1.04e-0419710550a6754a5109bec0d0de42adbfdf4db43ff60c3d2
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANXA2 CLLU1 CCRL2 PTPRE SH3TC1

1.04e-0419710558c24ffcd417da42fa9bcbe6bd0325360e537303f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_dorsal_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ARHGAP11A PTPRE ASPM DDX39A ARHGAP11B

1.06e-0419810555f0964c3aa7e1dc52cbb46e754078920b65bcb88
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ARHGAP11A PTPRE ASPM DDX39A ARHGAP11B

1.06e-041981055629d674a9c9108c1acb3f7af57bbdbf34bb0528e
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP11A NDC1 ASPM DDX39A ARHGAP11B

1.09e-041991055c9d15c84b9f8c87b4ea0008be7d5efc5f45efd1a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRB3 DOCK3 ABCC8 RNF128 CDH10

1.09e-041991055333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellBAL-Mild-cDC_1|Mild / Compartment, Disease Groups and Clusters

SETX CCRL2 RNF213 JAK2 PML

1.09e-041991055c55181bdec8952b54198f0d4c9c5c84265b16572
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK10 RCAN3 ASPM IL2RG ARHGAP11B

1.09e-0419910555a29db2610ba06a2248325a16cad755d20debf2c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRB3 DOCK3 ABCC8 RNF128 CDH10

1.09e-04199105519a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GABRB3 DOCK3 ABCC8 RNF128 CDH10

1.09e-041991055e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

RIPOR3 ABCA9 SLC7A2 SRPX2 SULF1

1.09e-0419910559503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RIPOR3 ABCA9 SRPX2 SULF1

2.25e-041261054f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RIPOR3 ABCA9 SRPX2 SULF1

2.25e-041261054fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RIPOR3 ABCA9 SRPX2 SULF1

2.25e-0412610543d507f829882d043f633db2612b76936e2042445
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RIPOR3 ABCA9 SRPX2 SULF1

2.25e-0412610541ac4cc747e466bc79e33b97608b19ad29a7a6a41
Drugtaurine

GABRB1 GABRB3 INSR PPP2R5E CLCA3P CLCA2 ABCC8 KCNJ16

1.28e-052311068CID000001123
Drugchi2 6

CHIA CHIT1

2.15e-0521062CID000063339
Druglaminarihexaose

CHIA CHIT1

2.15e-0521062CID000169096
DrugCID5289292

CHIA CHIT1

2.15e-0521062CID005289292
Drugglucoallosamidin B

CHIA CHIT1

2.15e-0521062CID000195827
DrugGlcNAc)8

CHIA CHIT1

2.15e-0521062CID000192495
Diseasenon-alcoholic fatty liver disease (implicated_via_orthology)

UBR2 INSR JAK2 ALDH1L2

6.47e-0636994DOID:0080208 (implicated_via_orthology)
Diseasepolycystic ovary syndrome

GABRB1 MYO10 INSR CDH10

5.03e-0560994EFO_0000660
DiseaseFamilial hyperinsulinism

INSR ABCC8

3.08e-048992cv:C3888018
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GABRB1 GABRB3 DLG1

6.03e-0449993DOID:0060037 (implicated_via_orthology)
Diseasepuberty onset measurement

DOCK3 DET1 KDM4C JMJD1C

8.47e-04125994EFO_0005677
Diseasetetralogy of Fallot (implicated_via_orthology)

DOCK1 DNAH5

9.88e-0414992DOID:6419 (implicated_via_orthology)
Diseaserenal cell carcinoma (biomarker_via_orthology)

ANXA2 ANXA2P2

9.88e-0414992DOID:4450 (biomarker_via_orthology)
DiseaseDown syndrome (implicated_via_orthology)

RCAN3 RCAN2

1.14e-0315992DOID:14250 (implicated_via_orthology)
Diseasehepatic encephalopathy (biomarker_via_orthology)

GABRB1 INSR

1.14e-0315992DOID:13413 (biomarker_via_orthology)
DiseaseMonogenic diabetes

INSR ABCC8

1.30e-0316992C3888631
DiseaseHIV-1 infection, Susceptibility to viral and mycobacterial infections

KDM4C FRMPD1

2.24e-0321992EFO_0000180, Orphanet_391311
DiseaseCOVID-19, mortality

GABRB3 KDM4C RCOR1 LRP2

2.62e-03170994EFO_0004352, MONDO_0100096
Diseasemyeloproliferative disorder

MRPS31 JAK2

3.18e-0325992EFO_0004251
DiseaseNeonatal diabetes mellitus

INSR ABCC8

3.18e-0325992C0158981

Protein segments in the cluster

PeptideGeneStartEntry
VRIKNVRYSESFRNA

UMODL1

796

Q5DID0
FIRKQINNIFLRFVY

PPP2R5E

216

Q16537
LRLSVSYLRVKSFFQ

AHRR

71

A9YTQ3
TLRFREQRYSLFKLV

CCRL2

226

O00421
SAKQRERRYSTVFLA

GJD2

101

Q9UKL4
YRSNTLTRVQFKLAL

B4GALNT2

541

Q8NHY0
RLSRYQQFKDFQRRI

DDX39B

326

Q13838
LSRYQQFKDFQRRIL

DDX39A

326

O00148
LTYVISFIFRNGRKN

ABCA9

1121

Q8IUA7
SQALRRFSTGRVYFK

ALDH1L2

6

Q3SY69
YARDKRFQQFIRKVT

ARHGEF2

356

Q92974
LRTSQKRSLYVRALF

DLG1

576

Q12959
RQTFITSVIKFLRQY

CHIA

116

Q9BZP6
LFSRRTSKQQVYFFL

ARHGEF26

671

Q96DR7
AQRQDIAFAYQRRTK

ANXA2

66

P07355
QRLFLIISATKYSRR

AP5Z1

46

O43299
KRRFFQYFDQLRQLR

DET1

316

Q7L5Y6
AQRQDIVFSYQRRTK

ANXA2P2

66

A6NMY6
LLSKQIGQFLRTYFR

SLC7A2

141

P52569
VYRRRFVQQKRAAIT

ASPM

2851

Q8IZT6
QLFKSFRRVRINFSN

RCAN2

46

Q14206
FQLFKSFRRVRINFS

RCAN3

81

Q9UKA8
SVVQVKNFFVNYRRR

RCOR1

416

Q9UKL0
VKTFFVSYRRRFNLE

RCOR2

366

Q8IZ40
LRYFFNFLRNVSLRS

ARHGAP11B

171

Q3KRB8
YRFRRFIQQFSQCKA

JAK2

231

O60674
QRFYAATSRQLKRLE

ABCC3

1126

O15438
NYRKAFLSAFRCEQR

NPY2R

331

P49146
RQTFVNSAIRFLRKY

CHIT1

116

Q13231
AYFFRFRKQRKAVVS

PTPRE

66

P23469
AELSRLRRQFISYTK

KTI12

316

Q96EK9
RRFRASNYQSTTRVK

CFAP20

101

Q9Y6A4
YFRRLSFSKNGVVRI

JMJD1C

1756

Q15652
NLLKSSNFRRYEVLR

HLCS

351

P50747
RRSLQAFQDYIRKTL

DDX58

6

O95786
ARAFVQRFRLQYRLA

DCAF8L2

211

P0C7V8
QQFYFLSKRRRNLLR

FBXO2

111

Q9UK22
IIQKNYRAFLLRRRF

MYO10

771

Q9HD67
KRQRVLSSRFKNEYV

KDM4C

1021

Q9H3R0
SFRLKRNIGYFILQT

GABRB1

236

P18505
SFRLKRNIGYFILQT

GABRB3

236

P28472
VKLNTSRTFYLQLRA

GARIN5A

201

Q6IPT2
NVRIRKYNLSSERFS

LRP2

4061

P98164
KIRRSYALVSLSFFR

INSR

396

P06213
YFASIRREFRKNQKL

MIEF1

31

L0R8F8
LSQRFKDTRVNYRKA

MMEL1

411

Q495T6
FRRRFLALLSYQFST

NAT10

771

Q9H0A0
SRFQATRQGRKYILV

OBSCN

2781

Q5VST9
TIRTCQKFLIQYNRR

POP5

106

Q969H6
YRFSLAAFLRLFQRA

DYNC2H1

3516

Q8NCM8
RARRLYQFDVSLANK

BNIP5

596

P0C671
VTVRSFKKRYFQLTQ

DOCK10

201

Q96BY6
FKFIVRSRILFNQLY

DOCK1

746

Q14185
RVKSFYRVNNVRKFR

DOCK3

1441

Q8IZD9
EKAFYTLRAQAINRR

CDH10

121

Q9Y6N8
RKRRSFLQTDYTSQV

FRMPD1

836

Q5SYB0
FRTFLQIIYSSNRNI

BTBD8

111

Q5XKL5
KLIIYLFSQNNRIRF

CLLU1

46

Q5K131
FRQVRDKTLKRGYFQ

DENND6A

156

Q8IWF6
AYKQLVRARFTRSFL

AREL1

571

O15033
AERFRSRLQLASFQY

CEP95

801

Q96GE4
FFNLSIYLNIQRRTR

HRH3

216

Q9Y5N1
QKRYTFRVRSRFNPL

IL2RG

216

P31785
LEKRSQSRIFYLRNF

RNMT

161

O43148
TSLFQKRDRYKRNFS

DNAH5

736

Q8TE73
DQIYRIFRKSRVLTN

SMG8

306

Q8ND04
QLNLYGFRKRRQCTF

HSFX1

156

Q9UBD0
SALLARTKNNIQRYF

MRPS31

46

Q92665
NNVRFSAYRTAIKIR

UTRN

2856

P46939
LRYFFNFLRNVSLRS

ARHGAP11A

171

Q6P4F7
ESSTILVVRYRRNFK

SPANXA1

46

Q9NS26
NYTARFSRFKNRETI

POLR2D

66

O15514
AFNRRKRNSIYVTVT

TMEM255A

21

Q5JRV8
NVFFESLQRRLSVYR

PML

106

P29590
TFNYQTRQEFLLRRF

GANAB

851

Q14697
TFRQRFRQFRYQDAA

SCAND1

106

P57086
FIFYSARRLRNARAQ

RNF128

226

Q8TEB7
QRLNVTITRAKYSLF

SETX

2406

Q7Z333
YQKARTFATELNVRR

SH3TC1

1301

Q8TE82
VQQLAKNTRYFRQRL

SPTLC3

431

Q9NUV7
RRKLTYQFSEAILQR

SPIC

186

Q8N5J4
RRFVNQLNTKYRDSL

TBC1D7

156

Q9P0N9
TTIRAFRYEARFQQK

ABCC8

1211

Q09428
YLFNATKRRVFFRNI

CLCA2

71

Q9UQC9
ATKQRAYFRNVSILI

CLCA3P

66

Q9Y6N3
LAYQRFRSRLQNFSR

RNF213

3816

Q63HN8
FRSRLQNFSRILTIY

RNF213

3821

Q63HN8
TSQKIAARAFAQRYL

RSPH3

391

Q86UC2
RLNFFRVYITLDRKI

TRIM77

281

I1YAP6
FRYRILRSQHFRTKS

SENP5

241

Q96HI0
FYFVRRRVLANALAS

SLC16A5

131

O15375
AVRNRSFREKALLFY

RIPOR3

846

Q96MK2
RQFQRLTRSYFNMVL

SRPX2

406

O60687
ESSTILVVRYRRNFK

SPANXD

46

Q9BXN6
RKRAQTIRFSYFALI

KCNJ16

176

Q9NPI9
RRDSIFCIQYNIRSF

MYH13

811

Q9UKX3
RFKTYQQFRRCLTLR

SMC6

926

Q96SB8
SSFFYKRLNQRERRN

SENP6

711

Q9GZR1
QLFRNFFLNSIYKSR

ROS1

2216

P08922
YSFLRGTKQLQVLRF

TSPAN12

211

O95859
QLLFYQRTFVSTLQR

MYO18B

976

Q8IUG5
ERYTALQAFKFRRVQ

UBR2

461

Q8IWV8
YRASRSQRKSQRQFL

SULF1

511

Q8IWU6
FQLKQYRSLILRFVR

ZRANB3

776

Q5FWF4
VVRFSALKRRFYVTT

WDR36

86

Q8NI36
QQKSRAFYRIQATRL

SLC8A2

346

Q9UPR5
RRIFQKFLQRYAILT

MYO1E

626

Q12965
IIQQYKFLRFRRSLL

NDC1

196

Q9BTX1
RFAFRASLKTAIYRI

NDC1

631

Q9BTX1