Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled photoreceptor activity

OPN1MW OPN1MW3 OPN1LW OPN1MW2

1.13e-05151964GO:0008020
GeneOntologyMolecularFunctionphotoreceptor activity

OPN1MW OPN1MW3 OPN1LW OPN1MW2

1.94e-05171964GO:0009881
GeneOntologyMolecularFunctioncalcium ion binding

NOX5 TRPM2 ZZEF1 HMCN2 NOTCH2NLB FKBP14 UNC13B SELE SELL SELP PITPNM2 CLEC6A ITSN1 CASR THBS4 NKD1 PLCH2 EGFL8 UNC13A

1.53e-0474919619GO:0005509
GeneOntologyBiologicalProcessregulation of membrane protein ectodomain proteolysis

PACSIN3 TSPAN17 APOE TSPAN5 TNFRSF1B

5.62e-06281935GO:0051043
GeneOntologyCellularComponentlysosomal HOPS complex

VPS39 VPS41

8.93e-0521982GO:1902501
GeneOntologyCellularComponentvacuolar HOPS complex

VPS39 VPS41

8.93e-0521982GO:1902500
GeneOntologyCellularComponentphotoreceptor disc membrane

OPN1MW OPN1MW3 OPN1LW OPN1MW2

9.91e-05261984GO:0097381
GeneOntologyCellularComponentAP-3 adaptor complex

VPS18 VPS39 VPS41

2.23e-04131983GO:0030123
GeneOntologyCellularComponentHOPS complex

VPS18 VPS39 VPS41

2.82e-04141983GO:0030897
GeneOntologyCellularComponentBMP receptor complex

ACVR1 ACVRL1

5.29e-0441982GO:0070724
DomainWD40_repeat_dom

DCAF8 DPH7 MAPK8IP3 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L SPAG9 DNAI3 WDFY4 VPS41 IFT122

4.01e-0729719015IPR017986
DomainOpsin_red/grn

OPN1MW OPN1MW3 OPN1LW

1.04e-0631903IPR000378
DomainSelectin_superfamily

SELE SELL SELP

1.04e-0631903IPR002396
Domain-

DCAF8 DPH7 MAPK8IP3 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L SPAG9 DNAI3 WDFY4 VPS41 IFT122

1.69e-06333190152.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF8 DPH7 MAPK8IP3 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L SPAG9 DNAI3 WDFY4 VPS41 IFT122

1.82e-0633519015IPR015943
DomainWD40

DCAF8 DPH7 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L DNAI3 WDFY4 IFT122

1.43e-0525919012PF00400
DomainWD40

DCAF8 DPH7 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L DNAI3 WDFY4 IFT122

2.01e-0526819012SM00320
DomainWD40_repeat

DCAF8 DPH7 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L DNAI3 WDFY4 IFT122

2.33e-0527219012IPR001680
DomainWD_REPEATS_2

DCAF8 DPH7 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L DNAI3 WDFY4 IFT122

2.99e-0527919012PS50082
DomainWD_REPEATS_REGION

DCAF8 DPH7 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L DNAI3 WDFY4 IFT122

2.99e-0527919012PS50294
DomainCHCR

VPS18 VPS39 VPS41

3.52e-0571903PS50236
DomainClathrin_H-chain/VPS_repeat

VPS18 VPS39 VPS41

5.59e-0581903IPR000547
DomainTMPIT

TMEM120B TMEM120A

1.03e-0421902IPR012926
DomainTMPIT

TMEM120B TMEM120A

1.03e-0421902PF07851
DomainJIP_LZII

MAPK8IP3 SPAG9

1.03e-0421902IPR032486
DomainJIP_LZII

MAPK8IP3 SPAG9

1.03e-0421902PF16471
DomainOPSIN

OPN1MW OPN1MW3 OPN1LW

1.18e-04101903PS00238
DomainWD_REPEATS_1

DCAF8 DPH7 PLAA EML5 NUP37 WDR49 WDR62 GNB1L DNAI3 WDFY4 IFT122

1.35e-0427819011PS00678
DomainOpsin

OPN1MW OPN1MW3 OPN1LW

1.61e-04111903IPR001760
DomainUnc-13

UNC13B UNC13A

3.07e-0431902IPR027080
DomainEGF

SELE SELL SELP TNC THBS4 MALRD1 EGFL8

3.08e-041261907PF00008
DomainJNK/Rab-associated_protein-1_N

MAPK8IP3 SPAG9

6.09e-0441902IPR019143
DomainJnk-SapK_ap_N

MAPK8IP3 SPAG9

6.09e-0441902PF09744
DomainMunc13_dom-2

UNC13B UNC13A

1.01e-0351902IPR014772
DomainMHD2

UNC13B UNC13A

1.01e-0351902PS51259
DomainMunc13_subgr_dom-2

UNC13B UNC13A

1.01e-0351902IPR019558
DomainMembr_traf_MHD

UNC13B UNC13A

1.01e-0351902PF10540
DomainRH2

MAPK8IP3 SPAG9

1.01e-0351902PS51777
DomainRH1

MAPK8IP3 SPAG9

1.01e-0351902PS51776
DomainDUF1041

UNC13B UNC13A

1.01e-0351902SM01145
DomainSH3_9

PACSIN3 MAP3K9 ITSN1 SH3KBP1 DBNL

1.20e-03781905PF14604
DomainTetraspanin_CS

TSPAN17 TSPAN14 TSPAN5

1.20e-03211903IPR018503
DomainC_TYPE_LECTIN_1

PKD1 SELE SELL SELP CLEC6A

1.34e-03801905PS00615
DomainSH3_1

PACSIN3 BLK ITSN1 SH3KBP1 DBNL HCK SPATA13

1.47e-031641907PF00018
DomainNa_trans_cytopl

SCN3A SCN5A

1.50e-0361902PF11933
DomainNa_trans_cytopl

SCN3A SCN5A

1.50e-0361902IPR024583
DomainLectin_C

PKD1 SELE SELL SELP CLEC6A

1.67e-03841905PF00059
DomainCLECT

PKD1 SELE SELL SELP CLEC6A

1.67e-03841905SM00034
DomainSH3

PACSIN3 BLK MAP3K9 ITSN1 SH3KBP1 DBNL HCK SPATA13

1.69e-032161908SM00326
DomainSH3

PACSIN3 BLK MAP3K9 ITSN1 SH3KBP1 DBNL HCK SPATA13

1.69e-032161908PS50002
DomainC_TYPE_LECTIN_2

PKD1 SELE SELL SELP CLEC6A

1.76e-03851905PS50041
DomainC-type_lectin-like

PKD1 SELE SELL SELP CLEC6A

1.85e-03861905IPR001304
DomainSH3_domain

PACSIN3 BLK MAP3K9 ITSN1 SH3KBP1 DBNL HCK SPATA13

1.90e-032201908IPR001452
DomainClathrin

VPS18 VPS41

2.09e-0371902PF00637
DomainMunc13_1

UNC13B UNC13A

2.09e-0371902IPR014770
DomainGS_dom

ACVR1 ACVRL1

2.09e-0371902IPR003605
DomainPKD

PKD1 PMEL

2.09e-0371902PF00801
DomainGS

ACVR1 ACVRL1

2.09e-0371902PS51256
DomainMHD1

UNC13B UNC13A

2.09e-0371902PS51258
DomainTGF_beta_GS

ACVR1 ACVRL1

2.09e-0371902PF08515
DomainGS

ACVR1 ACVRL1

2.09e-0371902SM00467
DomainDUF1041

UNC13B UNC13A

2.09e-0371902PF06292
DomainCAPS_dom

UNC13B UNC13A

2.09e-0371902IPR010439
DomainTM4_1

TSPAN17 TSPAN14 TSPAN5

2.27e-03261903PS00421
PathwayREACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION

OPN1MW3 OPN1LW OPN1MW2

5.07e-0581393MM14880
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SIFA_TO_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES

VPS18 VPS39 VPS41

7.55e-0591393M47777
PathwayREACTOME_OPSINS

OPN1MW3 OPN1LW OPN1MW2

1.07e-04101393MM15063
PathwayKEGG_MEDICUS_REFERENCE_TETHERING_OF_LATE_ENDOSOMES_AND_LYSOSOMES

VPS18 VPS39 VPS41

1.07e-04101393M47776
PathwayREACTOME_SARS_COV_2_MODULATES_AUTOPHAGY

VPS18 VPS39 VPS41

1.46e-04111393M45018
PathwayBIOCARTA_MONOCYTE_PATHWAY

SELE SELL SELP

1.46e-04111393MM1436
PathwayBIOCARTA_MONOCYTE_PATHWAY

SELE SELL SELP

1.46e-04111393M4956
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

OPN1MW3 OPN1LW APOE SDR9C7 OPN1MW2 DHRS9

2.93e-04921396MM14881
Pubmed

Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.

OPN1MW OPN1MW3 OPN1LW OPN1MW2

1.13e-094203429386880
Pubmed

Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

OPN1MW OPN1MW3 OPN1LW OPN1MW2

5.61e-09520342937147
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MON2 ABCA2 TMEM120B PIEZO1 NAGLU ZZEF1 MYORG MAPK8IP3 SCN5A PKD1 MFN2 IGSF3 UNC13B PITPNM2 VPS39 POLG MIB2 MED13L CIT SBNO2 AATK HPS6 SPATA13

1.54e-0711052032335748872
Pubmed

Genetic risk factors for cerebrovascular disease in children with sickle cell disease: design of a case-control association study and genomewide screen.

ACE SELE SELL SELP APOE

1.57e-0722203512871600
Pubmed

Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203334111401
Pubmed

No detectable endothelial- or leukocyte-derived L-selectin ligand activity on the endothelium in inflamed cremaster muscle venules.

SELE SELL SELP

1.96e-073203318381812
Pubmed

Cell-cell contact mechanisms.

SELE SELL SELP

1.96e-07320331375831
Pubmed

Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203328751656
Pubmed

The molecular genetics and evolution of red and green color vision in vertebrates.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203311545071
Pubmed

Co-expression of murine opsins facilitates identifying the site of cone adaptation.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203312511072
Pubmed

Mice lacking two or all three selectins demonstrate overlapping and distinct functions for each selectin.

SELE SELL SELP

1.96e-073203310352295
Pubmed

The selectins: vascular adhesion molecules.

SELE SELL SELP

1.96e-07320337542213
Pubmed

Molecular determinants of human red/green color discrimination.

OPN1MW OPN1LW OPN1MW2

1.96e-07320338185948
Pubmed

Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203338410159
Pubmed

Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203323350963
Pubmed

Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203320471354
Pubmed

Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203310567724
Pubmed

Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203314500905
Pubmed

Dermal and pulmonary inflammatory disease in E-selectin and P-selectin double-null mice is reduced in triple-selectin-null mice.

SELE SELL SELP

1.96e-073203311468173
Pubmed

Mechanisms of spectral tuning in the mouse green cone pigment.

OPN1MW3 OPN1LW OPN1MW2

1.96e-07320339238068
Pubmed

Evaluation of variants in the selectin genes in age-related macular degeneration.

SELE SELL SELP

1.96e-073203321521525
Pubmed

Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment.

SELE SELL SELP

1.96e-073203310500197
Pubmed

Multiple hypothalamic cell populations encoding distinct visual information.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203321224225
Pubmed

Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203336216501
Pubmed

Selectins: a family of adhesion receptors.

SELE SELL SELP

1.96e-07320331717161
Pubmed

Pathophysiologic importance of E- and L-selectin for neutrophil-induced liver injury during endotoxemia in mice.

SELE SELL SELP

1.96e-073203311050049
Pubmed

Role of primary and secondary capture for leukocyte accumulation in vivo.

SELE SELL SELP

1.96e-07320339440702
Pubmed

L-selectin and E-selectin expressed on monocytes mediating Ehrlichia chaffeensis attachment onto host cells.

SELE SELL SELP

1.96e-073203314592723
Pubmed

Selectin synthesis and inflammation.

SELE SELL SELP

1.96e-07320338851663
Pubmed

Higher-affinity oligosaccharide ligands for E-selectin.

SELE SELL SELP

1.96e-07320337680663
Pubmed

Role of selectins in the triggering, growth, and dissemination of T-lymphoma cells: implication of L-selectin in the growth of thymic lymphoma.

SELE SELL SELP

1.96e-073203315705798
Pubmed

Candidate gene analysis of selectin cluster in patients with multiple sclerosis.

SELE SELL SELP

1.96e-073203319240957
Pubmed

Selectin polymorphisms and perinatal morbidity in low-birthweight infants.

SELE SELL SELP

1.96e-073203316982492
Pubmed

X-linked cone dystrophy caused by mutation of the red and green cone opsins.

OPN1MW OPN1LW OPN1MW2

1.96e-073203320579627
Pubmed

Lectin adhesion proteins (P-, L- and E-selectins) as biomarkers in colorectal cancer.

SELE SELL SELP

1.96e-073203327775438
Pubmed

Selectins in human amniotic fluid and cord blood plasma. A preliminary report.

SELE SELL SELP

1.96e-073203320580062
Pubmed

Hydrocortisone reduced in vivo, inflammation-induced slow rolling of leukocytes and their extravasation into human conjunctiva.

SELE SELL SELP

1.96e-073203312200386
Pubmed

Effect of extracellular pH on selectin adhesion: theory and experiment.

SELE SELL SELP

1.96e-073203323442851
Pubmed

Gene-targeted mice reveal importance of L-selectin-dependent rolling for neutrophil adhesion.

SELE SELL SELP

1.96e-07320339612391
Pubmed

Plasma selectins in patients with obstructive sleep apnea.

SELE SELL SELP

1.96e-073203322836626
Pubmed

Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203331469404
Pubmed

Mobilization of stem/progenitor cells by sulfated polysaccharides does not require selectin presence.

SELE SELL SELP

1.96e-073203310841555
Pubmed

Emergence of novel color vision in mice engineered to express a human cone photopigment.

OPN1MW3 OPN1LW OPN1MW2

1.96e-073203317379811
Pubmed

Relationship between plasma aldosterone concentration and soluble cellular adhesion molecules in patients referred to coronary angiography.

SELE SELL SELP

1.96e-073203322068558
Pubmed

The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.

OPN1MW3 OPN1LW OPN1MW2

1.96e-07320337958444
Pubmed

Natural killer cells require selectins for suppression of subcutaneous tumors.

SELE SELL SELP

7.80e-074203319258505
Pubmed

ST3Gal-4 is the primary sialyltransferase regulating the synthesis of E-, P-, and L-selectin ligands on human myeloid leukocytes.

SELE SELL SELP

7.80e-074203325498912
Pubmed

Serum adhesion molecule levels as prognostic markers in patients with early systemic sclerosis: a multicentre, prospective, observational study.

SELE SELL SELP

7.80e-074203324516598
Pubmed

L-selectin shedding regulates leukocyte recruitment.

SELE SELL SELP

7.80e-074203311283159
Pubmed

Ultraviolet light exposure suppresses contact hypersensitivity by abrogating endothelial intercellular adhesion molecule-1 up-regulation at the elicitation site.

SELE SELL SELP

7.80e-074203312960307
Pubmed

P-, E-, and L-selectin mediate migration of activated CD8+ T lymphocytes into inflamed skin.

SELE SELL SELP

7.80e-074203312370362
Pubmed

Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203331461375
Pubmed

Melanopsin Contributions to the Representation of Images in the Early Visual System.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203328528909
Pubmed

Melanopsin-driven light adaptation in mouse vision.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203325308073
Pubmed

Mucin 16 is a functional selectin ligand on pancreatic cancer cells.

SELE SELL SELP

7.80e-074203322159147
Pubmed

Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203328103478
Pubmed

Molecular biology of the visual pigments.

OPN1MW OPN1LW OPN1MW2

7.80e-07420333303660
Pubmed

P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice.

SELE SELP APOE

7.80e-074203310620617
Pubmed

Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203326438865
Pubmed

Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203317249565
Pubmed

Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203338060327
Pubmed

Contribution of M-opsin-based color vision to refractive development in mice.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203334126082
Pubmed

Circulating P-, L- and E-selectins in pseudoxanthoma elasticum patients.

SELE SELL SELP

7.80e-074203318191640
Pubmed

Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.

OPN1MW3 OPN1LW OPN1MW2

7.80e-07420338088841
Pubmed

Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203331846668
Pubmed

Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation.

SELE SELL SELP

7.80e-07420339881978
Pubmed

Selectin-independent leukocyte rolling and adhesion in mice deficient in E-, P-, and L-selectin and ICAM-1.

SELE SELL SELP

7.80e-074203311158961
Pubmed

Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203316567464
Pubmed

S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.

OPN1MW3 OPN1LW OPN1MW2

7.80e-074203324801621
Pubmed

Glycan Bound to the Selectin Low Affinity State Engages Glu-88 to Stabilize the High Affinity State under Force.

SELE SELL SELP

7.80e-074203328011641
Pubmed

Establishment of experimental eosinophilic vasculitis by IgE-mediated cutaneous reverse passive arthus reaction.

SELE SELL SELP

7.80e-074203319389931
Pubmed

Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins.

SELE SELL SELP

7.80e-074203318606703
Pubmed

Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.

SELE SELL SELP

1.94e-065203320624949
Pubmed

A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203322090509
Pubmed

Adhesion molecules changes at 20 gestation weeks in pregnancies complicated by preeclampsia.

SELE SELL SELP

1.94e-065203317706337
Pubmed

Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203327033727
Pubmed

The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203311055434
Pubmed

A common integration locus in type B retrovirus-induced thymic lymphomas.

OPN1MW3 OPN1LW OPN1MW2

1.94e-06520331333116
Pubmed

Molecular pathways in bone marrow homing: dominant role of alpha(4)beta(1) over beta(2)-integrins and selectins.

SELE SELL SELP

1.94e-065203311588037
Pubmed

Melanopsin-based brightness discrimination in mice and humans.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203322633808
Pubmed

Selectin haplotypes and the risk of venous thrombosis: influence of linkage disequilibrium with the factor V Leiden mutation.

SELE SELL SELP

1.94e-065203318182036
Pubmed

Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203334099749
Pubmed

Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203326818794
Pubmed

Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203336631163
Pubmed

Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203310723722
Pubmed

Increased primary tumor growth in mice null for beta3- or beta3/beta5-integrins or selectins.

SELE SELL SELP

1.94e-065203314718670
Pubmed

Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.

OPN1MW3 OPN1LW OPN1MW2

1.94e-065203324058409
Pubmed

Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.

OPN1MW3 OPN1LW OPN1MW2

3.87e-06620338872469
Pubmed

A thyroid hormone receptor that is required for the development of green cone photoreceptors.

OPN1MW3 OPN1LW OPN1MW2

3.87e-066203311138006
Pubmed

Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.

OPN1MW3 OPN1LW OPN1MW2

3.87e-066203323288843
Pubmed

The value of gene 'knock-out' for assessing the role of cell adhesion molecules in renal disease.

SELE SELL SELP

3.87e-066203310048443
Pubmed

A functional role for circulating mouse L-selectin in regulating leukocyte/endothelial cell interactions in vivo.

SELE SELL SELP

3.87e-066203312165530
Pubmed

Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase.

OPN1MW3 OPN1LW OPN1MW2

3.87e-066203310395695
Pubmed

Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis.

OPN1MW3 OPN1LW OPN1MW2

3.87e-066203317436273
Pubmed

Telomere-related markers for the pseudoautosomal region of the mouse genome.

OPN1MW3 OPN1LW OPN1MW2

3.87e-06620331549575
Pubmed

Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium.

OPN1MW3 OPN1LW PMEL OPN1MW2

6.24e-0621203426876013
Pubmed

Polymorphisms in the platelet-specific collagen receptor GP6 are associated with risk of nonfatal myocardial infarction in Caucasians.

SELE SELP APOE THBS4

6.24e-0621203420227257
Pubmed

RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking.

VPS18 VPS39 VPS41

6.74e-067203325445562
Pubmed

NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina.

OPN1MW3 OPN1LW OPN1MW2

6.74e-067203318199774
Pubmed

Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.

OPN1MW3 OPN1LW OPN1MW2

6.74e-067203316574740
Cytoband1q22-q25

SELE SELP

5.82e-05320321q22-q25
GeneFamilyCD molecules|Selectins|Sushi domain containing|C-type lectin domain containing

SELE SELL SELP

5.05e-0731453945
GeneFamilyOpsin receptors

OPN1MW OPN1MW3 OPN1LW OPN1MW2

1.25e-06111454215
GeneFamilyWD repeat domain containing

DCAF8 DPH7 PLAA EML5 NUP37 WDR49 WDR62 DCAF8L2 GNB1L DNAI3 WDFY4 IFT122

1.37e-0626214512362
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PKD1 SELE SELL SELP

3.19e-044114541298
GeneFamilyUNC13 homologs

UNC13B UNC13A

3.79e-0441452836
GeneFamilyImmunoglobulin like domain containing

IGSF5 HMCN2 AGER SDK1 IGSF3 PTPRT KIRREL1

9.47e-041931457594
GeneFamilyType 1 receptor serine/threonine kinases

ACVR1 ACVRL1

1.31e-0371452345
GeneFamilyProteases, serine

PRSS45P PRSS29P PRSS50 PRSS42P

1.64e-03631454738
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PRTG IGSF5 HMCN2 NEGR1 SDK1 KIRREL1

1.91e-031611456593
GeneFamilyTransglutaminases

TGM7 EPB42

2.22e-0391452773
GeneFamilySodium voltage-gated channel alpha subunits

SCN3A SCN5A

2.22e-03914521203
GeneFamilyCD molecules|Tetraspanins

TSPAN17 TSPAN14 TSPAN5

2.31e-03331453768
GeneFamilyMitochondrial complex III: ubiquinol-cytochrome c reductase complex subunits|Apoptosome

UQCRB UQCR11

2.76e-03101452642
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

AGER CD4 KIRREL1

4.02e-03401453592
CoexpressionGROSS_HYPOXIA_VIA_ELK3_ONLY_UP

EPRS1 PGM1 SPAG9 SLC20A1 DHRS9

5.18e-06341965M1313
CoexpressionGROSS_HYPOXIA_VIA_ELK3_ONLY_UP

EPRS1 PGM1 SPAG9 SLC20A1 DHRS9

7.97e-06371965MM549
CoexpressionKUMAR_TARGETS_OF_MLL_AF9_FUSION

ACADS NAGLU PGM1 BLK SLC25A53 DNTT ITSN1 OGFOD2 VPS41 TRBC2 TRBC1 CTSB SPATA13

1.34e-0540819613M3284
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIDT1 INPP4B HPX SELL GNB1L PMEL CD4 TRBC2 TRBC1

4.72e-081592019a5509f0604ef0caef5ed1af83dd89c86686c73cc
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MON2 ACE INPP4B ZSWIM4 POLH APOE HPS6 TNFRSF1B CTRL

6.17e-081642019b77995958c938e10a526118f75d78cee72e0b207
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INPP4B CKS2 POLH SH3KBP1 PMEL CIT CD4 TRBC2 TRBC1

6.85e-081662019a41a20cef053c67da2d435e3e132ce28f1661c03
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

INPP4B HMCN2 SCN3A SDK1 TNC NTF3 B3GALNT2 SLC7A2 NKD1

1.57e-071832019818fd886e0188091310825f9145fa53328f2c979
ToppCellwk_08-11-Hematologic-Myeloid-APOE+_Mac1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KEL IL4I1 TECPR1 TRMT12 VPS18 APOE TNFRSF1B CTSB HCK

2.94e-071972019121ec3f6d978de2f6c2cc397f7327d2e5587ab8b
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ARL11 CKS2 AGER IL4I1 WDFY4 XIRP2 TVP23A HCK CFAP46

3.20e-0719920196dc446a5d183b01bdf227e45bd88d0b3d8b1c56a
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TRPM2 IL4I1 WDFY4 DHRS9 TNFRSF1B TRBC2 TRBC1 HCK

1.89e-061832018ffa7f2b2929ea4bd53f3f1ae23bd27f8bb4aac47
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Crym_(Crym)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYORG HPX FMO4 THBS4 PRSS50 PRSS42P

1.95e-068220169cd1b8a580566904a1ca0d4b5c48b2bf12a8898b
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Crym_(Crym)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYORG HPX FMO4 THBS4 PRSS50 PRSS42P

1.95e-06822016bc4e309c0128d126c47895e88d2250324c6ff81a
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Crym_(Crym)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYORG HPX FMO4 THBS4 PRSS50 PRSS42P

1.95e-068220160fb857a83f61d8c26be1b151903f4e6dc69397f9
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TRPM2 IL4I1 WDFY4 DHRS9 TNFRSF1B TRBC2 TRBC1 HCK

2.05e-0618520185ec2c3ae5c477645241e8eaf19d222562e1f7ed6
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

INPP4B HMCN2 SCN3A SDK1 TNC NTF3 B3GALNT2 NKD1

2.31e-06188201834e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellhematopoetic_progenitors-CD34+_CLP|hematopoetic_progenitors / Lineage and Cell class

BLK NEGR1 SCN3A TSPAN14 DNTT SH3KBP1 MED13L TRBC2

2.50e-061902018117abdafd294c85ccb5d8ea907e3c0491b7200b2
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

EXPH5 SDK1 WDR49 TNC DNAH2 DNAI3 CCDC17 CFAP46

2.81e-061932018ea345d34440b25f65358a53dc72831998d1c3620
ToppCellImmune-interstitial_macrophage_(C1Q_positive)|World / Lineage, Cell type, age group and donor

TRPM2 SLC18B1 ITSN1 CD4 DHRS9 TNFRSF1B CTSB HCK

2.81e-06193201864d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCellCaecum-(1)_T_cell-(15)_Treg|Caecum / shred on region, Cell_type, and subtype

INPP4B SELL TSPAN5 CD4 TNFRSF1B TRBC2 TRBC1 SPATA13

3.52e-06199201812c22b07a231c9dc548e9dc37e0a60296a4a6273
ToppCellCaecum-T_cell-Treg|Caecum / Region, Cell class and subclass

INPP4B SELL TSPAN5 CD4 TNFRSF1B TRBC2 TRBC1 SPATA13

3.52e-061992018ab0b32c077ac26d32a293dcf686af6984980793f
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial|GW12 / Sample Type, Dataset, Time_group, and Cell type.

SIDT1 PACSIN3 IL4I1 TNC FUZ APOE MYPOP SPATA13

3.66e-062002018be1abe5bb1ce4e7dfec63af4ed0fc5b96bf77866
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HMCN2 IL4I1 CLEC6A STBD1 WDFY4 CD4

4.33e-06942016dfc3f7977b9df433009d1d2d465b64a2de5806e2
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Ccnd1_(Mural.Rgs5Acta2.Ccnd1)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HMCN2 IL4I1 CLEC6A STBD1 WDFY4 CD4

4.33e-06942016d78535a7a0fda7299b01912333b944dc5e0a0361
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC5A7 ARSI SCN5A SDK1 IGSF3 SELP CIT

4.39e-06145201778f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIDT1 INPP4B SELL SH3KBP1 DYNLT2 TRBC2 TRBC1

5.25e-0614920174fda987bc7bb6d1dbd41b8f1f8c1bc59613255a8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCAF8 ACE NEGR1 LGI4 TRBC2 CCDC17 UNC13A

5.49e-0615020171270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCAF8 ACE NEGR1 LGI4 TRBC2 CCDC17 UNC13A

5.49e-061502017156118ce1d69522624196410cba18b8354cd0bb4
ToppCellfacs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l8|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

USP9Y DGAT2 SELL CLEC6A DHRS9 TNFRSF1B SPATA13

6.25e-061532017338684d420b01e32918fa19048ccdda234942ce1
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

EXPH5 IGSF5 ATP8A1 AGER LGI4 PLCH2 SLC28A1

6.52e-0615420178a643d91896af9b630a715fb284c1523d01ad1a3
ToppCellfacs-Marrow-Granulocytes-24m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 KEL EVC2 CLEC6A ITSN1 APOE TRIM10

9.08e-0616220172787be283b7a705647058aeb9bc54006ce5ffe95
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

INPP4B MYORG BLK HMCN2 TBXA2R PITPNM2 NTF3

1.02e-0516520173d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIDT1 INPP4B SH3KBP1 CD4 TNFRSF1B TRBC2 TRBC1

1.02e-051652017d91fabc5b26c27577eea27be8a305fec5c004164
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYORG FMO4 TNC LGI4 THBS4 PRSS50

1.13e-051112016cb45322fbeafec2f1ab7a3727da69abb1047567d
ToppCellGlobus_pallidus-Macroglia-ASTROCYTE-Gja1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MYORG FMO4 TNC LGI4 THBS4 PRSS50

1.13e-0511120167d7aad8e9811c67fb9abfb4ebc75def01a517adf
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.15e-0516820174b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.15e-051682017689c41f6e9f65381570991cc311cba49a57ec955
ToppCelldroplet-Lung-nan-18m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.20e-051692017ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCelldroplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.20e-051692017c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.20e-051692017b059304543876f514d5c7214f1f0a2da00f10a67
ToppCelldroplet-Lung-21m-Hematologic-myeloid-non-classical_monocyte|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.20e-051692017945f737984c4de70a4e9c214053b005358053dd5
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INPP4B CKS2 SELE SH3KBP1 CD4 TRBC2 TRBC1

1.24e-0517020172d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.29e-05171201700739085fdbc4d64c9faacba2c2adeab580dd2b1
ToppCelldroplet-Lung-nan-21m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.34e-05172201751bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCelldroplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.34e-051722017be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

INPP4B SELL TSPAN5 CD4 TNFRSF1B TRBC2 TRBC1

1.34e-051722017c74c1d47b133eb5d0f762a06e421252a76b4672b
ToppCelldroplet-Lung-1m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE CKS2 APOE TNFRSF1B CTSB HCK SPATA13

1.34e-0517220175f58ff6cac32546d07b2a49ed250b6c7aa417188
ToppCellMild-CD4+_T_Exhausted|Mild / Disease group and Cell class

TSPAN14 SELL SH3KBP1 DBNL CD4 TVP23A CTSB

1.50e-0517520176df099f37875f2cd63502b732a2e07ebfec50e47
ToppCellHealthy_Control-Lymphoid-T-Treg|Healthy_Control / Condition, Lineage, Cell class and cell subclass

TMEM120B SELL SELP TSPAN5 TNFRSF1B TRBC2 TRBC1

1.56e-0517620177765a5b04ac117d525201f8eb08e1754e55942ff
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE APOE TNFRSF1B CTSB HCK RPL9 SPATA13

1.67e-051782017a1f2c134bb7596f678fb4cc11405c374d926ea0f
ToppCellStriatum-Macroglia-ASTROCYTE-Gja1|Striatum / BrainAtlas - Mouse McCarroll V32

MYORG HPX TNC LGI4 THBS4 PRSS50

1.68e-051192016d47880ef1cff036192c43646a04fa8598dd7e1f4
ToppCellStriatum-Macroglia-ASTROCYTE|Striatum / BrainAtlas - Mouse McCarroll V32

MYORG HPX TNC LGI4 THBS4 PRSS50

1.68e-0511920160583387cc4497cf991fa42a81f2f66d9c6b774eb
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NOX5 SDK1 WDR49 DNAH2 DNAI3 CCDC17 CFAP46

1.74e-0517920175e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCelldroplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE APOE TNFRSF1B CTSB HCK RPL9 SPATA13

1.80e-05180201705cce7e3c13dd3e3b70aaad841097be51cfadad3
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARSI SDK1 TNC APOE DNAI3 SLC7A2 NKD1

1.80e-0518020179b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYORG HPX PRSS45P LGI4 THBS4 PRSS50

1.85e-0512120168334a6b2ced1d6a4808458d6d4232d1b688ba28a
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYORG HPX PRSS45P LGI4 THBS4 PRSS50

1.85e-0512120164b33eeed7b70da120133b14d42c104d2461d52dc
ToppCellHippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYORG HPX PRSS45P LGI4 THBS4 PRSS50

1.85e-051212016a33e4ae0b0efb702db1b646ac0486e3b6ce48457
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARSI SDK1 TNC APOE DNAI3 SLC7A2 NKD1

1.86e-0518120179e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellCOVID-19-T_cells-Tregs|COVID-19 / group, cell type (main and fine annotations)

INPP4B SELL SELP TSPAN5 TNFRSF1B TRBC2 TRBC1

1.86e-051812017534659cf754326c6a73c0daa30e9d610612a0292
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

USP9Y ATP8A1 NEGR1 SELL FUZ WDFY4 GYS1

1.86e-051812017277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

USP9Y ATP8A1 NEGR1 SELL FUZ WDFY4 GYS1

1.86e-0518120172caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIDT1 INPP4B SELL SH3KBP1 CD4 TRBC2 TRBC1

1.86e-05181201761c6e000db7047fda4b4bb5024f3af24577e7d29
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIDT1 INPP4B SELL SH3KBP1 CD4 TRBC2 TRBC1

1.86e-0518120176a32eb83aa39484ca43c91e6b58302d8dea84b7e
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-SELL+_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DCAF8 INPP4B SELL CD4 TRBC2 TRBC1 RPL9

1.86e-05181201704ed65362737e3e70134342127a3f4134a0e2eef
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIDT1 INPP4B SELL SH3KBP1 CD4 TRBC2 TRBC1

1.93e-05182201701ae44b465e509b0aa75ccf61bd9bc0a89d6758c
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEGR1 SDK1 STBD1 TNC ITSN1 MYPOP KIRREL1

2.00e-051832017ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SIDT1 INPP4B SELL SH3KBP1 CD4 TRBC2 TRBC1

2.00e-05183201741ae679e7332fcafa9101e62a4a910ebae63e87c
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HMCN2 SCN3A SDK1 TNC NTF3 B3GALNT2 NKD1

2.00e-051832017cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellfacs-Thymus|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INPP4B IGSF3 TECPR1 DNTT TBXA2R CD4 SPATA13

2.07e-05184201758beef66bbbde2479ec69dfef392d5941cedf230
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

CPAMD8 PRTG ATP8A1 UNC13B PITPNM2 CIT MALRD1

2.15e-051852017673f0c688ae6984bc8027df2da335787924f4137
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BLK SCN3A DNTT SELL WDFY4 TRBC2 HCK

2.15e-0518520178fc357ee041bfd588986730a52ea2021b5f88941
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARL11 TRPM2 SH3KBP1 WDFY4 CD4 TNFRSF1B HCK

2.22e-051862017e152bdd837366e3e0b8bcfdb4d53f0685f2e803a
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-T_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIDT1 INPP4B TECPR1 SELL TBXA2R CD4 RPL9

2.30e-0518720171387981d224cb9e846ed18e366736855a4eb827e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BLK ATP8A1 SELL SH3KBP1 CD4 TNFRSF1B TRBC1

2.46e-051892017b87d586a9570fa54f3e0c6bd4731c5badcaedae6
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

INPP4B HMCN2 SCN3A SDK1 TNC NTF3 NKD1

2.46e-0518920176b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BLK ATP8A1 SELL SH3KBP1 CD4 TNFRSF1B TRBC1

2.46e-051892017823d6debd09e440ddf36c54af24a5f20e222a21e
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BLK ATP8A1 SELL SH3KBP1 CD4 TNFRSF1B TRBC1

2.46e-05189201747c2b419b081d5bf75da5e3d9a0e05a70362dfe7
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SIDT1 BLK NEGR1 SELL FUZ WDFY4 SLC20A1

2.63e-051912017989bf108c7f2c78dd7f14481570f1819673a5469
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SIDT1 BLK NEGR1 SELL FUZ WDFY4 SLC20A1

2.63e-051912017bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARL11 TRPM2 SH3KBP1 WDFY4 CD4 TNFRSF1B HCK

2.63e-051912017c72e62cf5b45c04ee5e7719db31f917c4f76b1e4
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TRPM2 SLC18B1 CD4 DHRS9 TNFRSF1B CTSB HCK

2.63e-05191201724d75b7e1d6fb9d24aa7844f584ee888a449841f
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SIDT1 BLK NEGR1 SELL FUZ WDFY4 SLC20A1

2.63e-0519120173e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SIDT1 BLK NEGR1 SELL FUZ WDFY4 SLC20A1

2.72e-0519220172e8611d65090e39f1a6e74c972288e7b68376d15
ToppCellCOPD-Lymphoid|COPD / Disease state, Lineage and Cell class

SIDT1 INPP4B ATP8A1 SH3KBP1 TSPAN5 TRBC2 TRBC1

2.72e-051922017064fefb8212fadab0ff441f4bf643559b7fdb25d
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SIDT1 BLK NEGR1 SELL FUZ WDFY4 SLC20A1

2.72e-051922017d9ff2293358c8b031ba212021012e058014ff472
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

SIDT1 BLK NEGR1 SELL FUZ WDFY4 SLC20A1

2.72e-051922017f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SIDT1 BLK NEGR1 SELL FUZ WDFY4 SLC20A1

2.72e-05192201743569726df281eebe57499e0993b9fd9d36118c2
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARSI SDK1 TNC APOE DNAI3 SLC7A2 NKD1

2.72e-051922017deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

WDR49 DNAH2 DNAI3 PTPRT CCDC17 CFAP46 SPATA13

2.81e-0519320170e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 SH3KBP1 WDFY4 CD4 TNFRSF1B CTSB HCK

2.81e-051932017f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

UQCRB UQCR11 IL4I1 APOE CD4 SLC28A1 CTSB

2.81e-051932017855b605efa4c9ab7948e8aa231865fa0467c06d9
ToppCell10x3'2.3-week_17-19-Myeloid_macrophage-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

UQCRB UQCR11 IL4I1 APOE CD4 SLC28A1 CTSB

2.81e-051932017cc77889acbadf1acb278daa0ed0db0253acf041d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 PIEZO1 SPTBN2 SCN3A SDK1 VWA5B1 TSPAN5

2.91e-05194201704bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPAMD8 PIEZO1 SPTBN2 SCN3A SDK1 VWA5B1 TSPAN5

2.91e-05194201769bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 SPTBN2 INPP4B SDK1 VWA5B1 TSPAN5 SLC7A2

2.91e-0519420174579b4a44f7c731553a284843c296866027d7c0e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 SH3KBP1 WDFY4 CD4 TNFRSF1B CTSB HCK

2.91e-0519420170866ab6792cee274a71991d5c37a37f574ff446e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 ITSN1 WDFY4 CD4 TNFRSF1B CTSB HCK

2.91e-051942017c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO1 SPTBN2 INPP4B SDK1 VWA5B1 TSPAN5 SLC7A2

3.01e-0519520173d6d3de8ada6dce3dc789c15b50cc066e7100496
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 BLK SH3KBP1 WDFY4 CD4 TNFRSF1B HCK

3.01e-0519520172d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_2-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

INPP4B SELL SH3KBP1 TSPAN5 TRBC2 TRBC1 TRAV13-2

3.01e-0519520176ddce0cce14f737e45b8f57802c6a8ad07686262
ToppCellBAL-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_2|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

INPP4B SELL SH3KBP1 TSPAN5 TRBC2 TRBC1 TRAV13-2

3.01e-051952017e6212373cc3c6c98f76e104e2ac1afa68965cc5f
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM2 SIDT1 WDFY4 CD4 DHRS9 TNFRSF1B HCK

3.01e-051952017c14d730dd5c94247bc09711eaa5a53bd5a5957be
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 BLK SH3KBP1 WDFY4 CD4 TNFRSF1B HCK

3.01e-0519520177b6c69df943842b566a596e30bb50dbe80dccc83
DrugGSC-150

HPX SELE SELL SELP

2.54e-0851944CID000196962
DrugNSC295110

SELE SELL SELP

6.09e-0731943CID005458605
Drugsuccinyl chloride

SELE SELL SELP

6.02e-0651943CID000010970
DrugONO-4057

SELE SELL SELP

1.20e-0561943CID006438358
Drugsulfur trioxide-trimethylamine

SELE SELL SELP

1.20e-0561943CID000222852
Drugstearyl sulfate

SELE SELL SELP

1.20e-0561943CID000008912
DrugSri 8835

SELE SELL SELP

1.20e-0561943CID000479975
Drugdimethyl(methylthio)sulfonium

SELE SELL SELP

2.08e-0571943CID002737115
DrugA1-E

ABCA2 OPN1MW DNTT SELE OPN1LW SDR9C7

2.10e-05661946CID005326966
Diseaseblue cone monochromacy (implicated_via_orthology)

OPN1MW OPN1MW3 OPN1LW OPN1MW2

1.70e-0941914DOID:0050679 (implicated_via_orthology)
Diseasemyocardial infarction (biomarker_via_orthology)

ACE AGER MFN2 SELP TNC CASR TNFRSF1B CTSB

1.03e-051601918DOID:5844 (biomarker_via_orthology)
DiseaseIgA glomerulonephritis (is_implicated_in)

ACE SELE SELL TNFRSF1B

4.09e-05301914DOID:2986 (is_implicated_in)
DiseaseCone monochromatism

OPN1MW OPN1LW

4.17e-0521912cv:C0339537
DiseaseBORNHOLM EYE DISEASE

OPN1MW OPN1LW

4.17e-0521912C3159311
DiseaseAchromatopsia incomplete, X-linked

OPN1MW OPN1LW

4.17e-0521912C2931753
DiseaseRed-green dyschromatopsia

OPN1MW OPN1LW

4.17e-0521912cv:C0155016
Diseasefibrodysplasia ossificans progressiva (implicated_via_orthology)

ACVR1 ACVRL1

4.17e-0521912DOID:13374 (implicated_via_orthology)
DiseaseCone monochromatism

OPN1MW OPN1LW

4.17e-0521912C0339537
DiseaseBLUE CONE MONOCHROMACY

OPN1MW OPN1LW

4.17e-0521912303700
Diseasephosphoglucomutase-1 measurement

PGM1 APOE

4.17e-0521912EFO_0021859
Diseaseblue cone monochromacy (is_implicated_in)

OPN1MW OPN1LW

4.17e-0521912DOID:0050679 (is_implicated_in)
Diseaseextrinsic allergic alveolitis (is_marker_for)

ACE TNC TNFRSF1B

9.22e-05141913DOID:841 (is_marker_for)
Diseaseend stage renal disease (is_marker_for)

AGER CASR APOE TNFRSF1B

2.24e-04461914DOID:783 (is_marker_for)
Diseaserenal fibrosis (is_marker_for)

ACE AGER

2.48e-0441912DOID:0050855 (is_marker_for)
Diseaseatherosclerosis (biomarker_via_orthology)

AGER SELP CASR

2.81e-04201913DOID:1936 (biomarker_via_orthology)
Diseasenephrotic syndrome (implicated_via_orthology)

ACE SH3KBP1 KIRREL1

4.89e-04241913DOID:1184 (implicated_via_orthology)
Diseasesolute carrier family 22 member 16 measurement

SELP MALRD1

6.15e-0461912EFO_0802079
DiseaseGlycogen Storage Disease

PGM1 GYS1 G6PC1

6.96e-04271913C0017919
Diseaseproteinuria (is_implicated_in)

ACE AGER

8.57e-0471912DOID:576 (is_implicated_in)
Diseaseexfoliation syndrome (is_implicated_in)

ACVR1 APOE

8.57e-0471912DOID:13641 (is_implicated_in)
DiseaseL-Selectin measurement

SELE SELL SELP

1.05e-03311913EFO_0008202
Diseasefear of minor pain measurement

NAGLU TRMT12 HCK

1.05e-03311913EFO_0008340
Diseasecerebrovascular disease (is_implicated_in)

SELE APOE

1.14e-0381912DOID:6713 (is_implicated_in)
Diseasecytidine measurement

APOE SLC28A1

1.14e-0381912EFO_0800645
Diseaseresponse to selective serotonin reuptake inhibitor, body mass index

PTPRT PLCH2

1.14e-0381912EFO_0004340, EFO_0005658
Diseasepulmonary sarcoidosis (is_marker_for)

TNC NTF3 TNFRSF1B

1.15e-03321913DOID:13406 (is_marker_for)
Diseasetype 1 diabetes mellitus (is_marker_for)

ACE AGER SELE APOE

1.24e-03721914DOID:9744 (is_marker_for)
Diseasefatty liver disease (biomarker_via_orthology)

MFN2 CTSB G6PC1

1.26e-03331913DOID:9452 (biomarker_via_orthology)
DiseaseCardiovascular Diseases

ACE SELE APOE

1.63e-03361913C0007222
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN3A SCN5A

1.81e-03101912DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN3A SCN5A

1.81e-03101912DOID:0080422 (implicated_via_orthology)
Diseasetype 2 diabetes mellitus (is_marker_for)

MFN2 SELP APOE CTSB G6PC1

1.96e-031361915DOID:9352 (is_marker_for)
Diseaseglomerulosclerosis (implicated_via_orthology)

ACE APOE

2.21e-03111912DOID:0050851 (implicated_via_orthology)
Diseasephospholipid measurement

DGAT2 ILRUN APOE DHRS9 CTSB

2.22e-031401915EFO_0004639
Diseasekidney disease (implicated_via_orthology)

BLK KIRREL1 HCK

2.37e-03411913DOID:557 (implicated_via_orthology)
DiseaseMethionine sulfoxide measurement

FMO4 CD4

2.64e-03121912EFO_0021650
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN3A SCN5A

2.64e-03121912DOID:0060170 (implicated_via_orthology)
Diseaseanxiety disorder, stress-related disorder

SDK1 PTPRT

2.64e-03121912EFO_0006788, EFO_0010098
DiseaseZellweger Spectrum

PEX16 HSD17B4

3.10e-03131912C3658299
DiseaseZellweger-Like Syndrome

PEX16 HSD17B4

3.10e-03131912C0751594
Diseaseintracranial aneurysm (biomarker_via_orthology)

AGER CTSB

3.10e-03131912DOID:10941 (biomarker_via_orthology)
DiseaseConnective Tissue Diseases

ACVR1 PKD1

3.10e-03131912C0009782
Diseaseintermediate coronary syndrome (is_marker_for)

ACE SELP

3.10e-03131912DOID:8805 (is_marker_for)
DiseaseDepressed mood

ACE SELP

3.10e-03131912C0344315
Diseasemultisite chronic pain

BBX SDK1 ILRUN LEMD2

3.42e-03951914EFO_0010100
DiseaseKawasaki disease (is_marker_for)

AGER SELP

3.60e-03141912DOID:13378 (is_marker_for)
Diseaserespiratory quotient

AATK UNC13A

3.60e-03141912EFO_0005189
Diseasetransient cerebral ischemia (biomarker_via_orthology)

TRPM2 ACVRL1 AGER MFN2 APOE

3.64e-031571915DOID:224 (biomarker_via_orthology)
Diseasechronic obstructive pulmonary disease (is_marker_for)

AGER SELP NTF3 TNFRSF1B

3.69e-03971914DOID:3083 (is_marker_for)
Diseasehearing impairment

FANCG HSD17B4 NTF3 APOE

3.83e-03981914C1384666
Diseasemyocardial infarction (is_implicated_in)

ACE AGER SELP APOE

3.97e-03991914DOID:5844 (is_implicated_in)
Diseasecoronary artery disease (is_implicated_in)

ACE AGER SELE APOE

4.11e-031001914DOID:3393 (is_implicated_in)
DiseaseAdrenoleukodystrophy, Neonatal

PEX16 HSD17B4

4.14e-03151912C0282525
Diseasepulmonary fibrosis (biomarker_via_orthology)

ACE AGER MFN2

4.18e-03501913DOID:3770 (biomarker_via_orthology)
Diseasediabetic retinopathy (is_implicated_in)

ACE AGER APOE

4.18e-03501913DOID:8947 (is_implicated_in)
Diseaseobesity (is_marker_for)

AGER MFN2 SELP APOE

4.26e-031011914DOID:9970 (is_marker_for)
Diseaseepilepsy (implicated_via_orthology)

SCN3A SCN5A UNC13B CIT UNC13A

4.26e-031631915DOID:1826 (implicated_via_orthology)
Diseasecerebral amyloid angiopathy

APOE SLC7A2 SLC28A1

4.43e-03511913EFO_0006790
DiseaseZellweger Syndrome

PEX16 HSD17B4

4.71e-03161912C0043459
Diseasepneumonia (is_implicated_in)

ACE TNFRSF1B

4.71e-03161912DOID:552 (is_implicated_in)
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

ACE PKD1

4.71e-03161912DOID:0110861 (implicated_via_orthology)
Diseaseprimary autosomal recessive microcephaly (is_implicated_in)

NUP37 WDR62

4.71e-03161912DOID:0070296 (is_implicated_in)
DiseaseCOVID-19, mortality

MYORG SELL CLEC6A BPIFC APOE

5.09e-031701915EFO_0004352, MONDO_0100096
DiseaseSchizophrenia

SPTBN2 ACE PLAA EML5 AGER TMEM245 VPS39 NTF3 GNB1L APOE SBNO2 TNFRSF1B CTRL

5.13e-0388319113C0036341
DiseaseGlycogen storage disease

PGM1 G6PC1

5.32e-03171912cv:C0017919
Diseasephosphoglyceric acid measurement

NTF3 TVP23A

5.32e-03171912EFO_0010523
DiseaseRenal Insufficiency

ACE APOE

5.32e-03171912C1565489
Diseaserenal fibrosis (implicated_via_orthology)

ACE AGER

5.32e-03171912DOID:0050855 (implicated_via_orthology)
DiseaseC-reactive protein measurement

ACADS NAGLU ZZEF1 MAPK8IP3 BLK PKD1 ILRUN THUMPD3 MIB2 APOE CIT MYPOP DHRS9 CTSB G6PC1 OR4A4P

5.40e-03120619116EFO_0004458
Diseasephenylalanine measurement

NUP37 VPS18 APOE

5.47e-03551913EFO_0005001
Diseasevascular endothelial growth factor measurement

EVC2 POLH DNAH2

5.75e-03561913EFO_0004762
Diseaselupus nephritis (is_implicated_in)

AGER TNFRSF1B

5.96e-03181912DOID:0080162 (is_implicated_in)
Diseasenon-alcoholic fatty liver disease (is_implicated_in)

DGAT2 SAMM50

5.96e-03181912DOID:0080208 (is_implicated_in)
DiseaseAlzheimer's disease (biomarker_via_orthology)

AGER MFN2 APOE

6.34e-03581913DOID:10652 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
NKGLIWDTMVGTVWI

UNC13A

66

Q9UPW8
LGSGIWVDEEKWHQL

BEND5

301

Q7L4P6
WVLIGIVSWGTKNCN

CTRL

226

P40313
ISSLGDRKWWSAVVE

EPB42

81

P16452
GLIEKDTNGEVLWVW

DENND10P1

16

Q6NSW5
RGLEASWIWVQLRTG

CCDC17

406

Q96LX7
EQWAGQAGAWVRAVL

EGFL8

226

Q99944
TEWQSGQRWELALGR

APOE

36

P02649
KWIERVVGWLGKVFL

ANAPC2

291

Q9UJX6
DNRGATKILADWWAV

BBX

106

Q8WY36
AEAWNFWTRKGLVSG

CTSB

156

P07858
RAEGDSWVLNGTKAW

ACADS

171

P16219
AWEGWRDKAGRAILQ

ACE

786

P12821
WNTAVQAAIRVGEWK

ARSI

411

Q5FYB1
RNITGKIWLASEAWA

CASR

286

P41180
GRLEAAILSGWKTFW

FBXO4

21

Q9UKT5
EVWRGSWQGENVAVK

ACVR1

221

Q04771
WAELAKVARKQGVWD

CFAP46

581

Q8IYW2
GVWKVGEAIWVAENL

LINC00528

146

Q8N1L1
VWRGLWHGESVAVKI

ACVRL1

216

P37023
DIILTVGGWNVAIWK

DNAI3

686

Q8IWG1
TVGELWAFITGWNLI

SLC7A2

106

P52569
RQWEAWRSVLGDEKS

CIT

1041

O14578
WAGARAENVVGIGTW

ARMCX4

1166

Q5H9R4
QVLRNGAWEIVHWEK

ATP8A1

136

Q9Y2Q0
GINLALAWSGQEAIW

NAGLU

161

P54802
SAAWARKGIEEWIGR

NKD1

26

Q969G9
IREKDGLWAVLAWLS

PGM1

386

P36871
AVGAWVLVLSLWGAV

AGER

6

Q15109
ITNRWSFDGIDRWIK

RAB40C

96

Q96S21
AVGAVGLVWATDWRL

UQCR11

26

O14957
AKLAIVGIAFSWIWA

OPN1LW

166

P04000
AKLAIVGIAFSWIWA

OPN1MW3

166

P0DN78
AVSASGKWLDGIRKW

UQCRB

6

P14927
RWLRWVTQQFKTIAG

NOX5

26

Q96PH1
AKLAIVGIAFSWIWA

OPN1MW2

166

P0DN77
QVRQLAWVGDGVWVS

SPAG9

1091

O60271
AWVGDGVWVSIRLDS

SPAG9

1096

O60271
LWDVGGQAPLRASWK

ARL11

61

Q969Q4
WFTLGILEALKGWDQ

FKBP14

76

Q9NWM8
GTELWERDREVWNGK

NOTCH2NLB

256

P0DPK3
DLARVLGWGAFWNKS

DGKK

581

Q5KSL6
GTGERWNLVVWLRAS

OGFOD2

296

Q6N063
IVGLNWLQAVIKRWW

KATNBL1

236

Q9H079
INIAGWKTDGKWQRD

PNLIPRP3

91

Q17RR3
GSAGKALAVWSLDWQ

GNB1L

226

Q9BYB4
GVRLGTVGEQNSWVW

IFT122

311

Q9HBG6
ARKIGLQKLWEWCIG

MED13L

1871

Q71F56
VRQLAWIGDGVWVSI

MAPK8IP3

1091

Q9UPT6
WLNRSSIIFAGGDKW

NEGR1

71

Q7Z3B1
WILSSNKDVGIWLKG

LEMD2

326

Q8NC56
SLRWWKDGVALAAFG

HMCN2

1841

Q8NDA2
WDRVWANVGKSLNCI

INPP4B

521

O15327
SGDDLKVIVWDWVRQ

DCAF8L2

246

P0C7V8
QWVCVVLLVVSWVGG

OR4A47

136

Q6IF82
VKGALWKVLWRGRDS

OR2Y1

296

Q8NGV0
GSDDLKVVVWDWVRR

DCAF8

211

Q5TAQ9
PGKWDGARNAILTQW

FMO4

476

P31512
FIRVQNEGTGKSSWW

FOXO6

151

A8MYZ6
SGKVKVWGNVVTVEW

HNRNPR

311

O43390
WEVVAERAWKGGTES

POLG

1041

P54098
WWQALDGKLRGDLIS

EVC2

1191

Q86UK5
WIGIRKVNNVWVWVG

SELE

71

P16581
IRKIGGIWTWVGTNK

SELL

91

P14151
KRDIRWLQGVTGEWF

EXPH5

46

Q8NEV8
SWREKIARDVAGATW

GNL1

306

P36915
EATALWWRLEAQTKG

FANCG

566

O15287
WAETWVLTLAGVARI

MON2

1111

Q7Z3U7
TFKVGAVAGNDWLIW

NUP37

221

Q8NFH4
LDIGEVAAKWWGQKR

PITPNM2

906

Q9BZ72
NNKLVGWRWIRIDTS

NTF3

231

P20783
QASGKGLEWVAVIWR

IGHV8-51-1

56

P0DTE2
AAGQIQAWWRGVLVR

IQCF3

36

P0C7M6
VGGVVWKAVGWRLIA

MFN2

621

O95140
VRVTSWDGRKWGELE

NSUN4

231

Q96CB9
WNVSGVVTEGWVKAE

PTPRT

136

O14522
AKLAIVGIAFSWIWA

OPN1MW

166

P04001
KAWIAGEWQVLHREG

PRTG

861

Q2VWP7
ARVAWTAGVVLFVWV

MRGPRG

171

Q86SM5
NILVWSVIGNKRTGW

MALRD1

1836

Q5VYJ5
LDIVGIWWTVTNFGE

FRG1

41

Q14331
TRAAAWWGRLEGAKA

LINC00482

206

Q8N8I6
VVLEESGEWWKARSL

HCK

106

P08631
VKTWRIQNSGAEAWP

ILRUN

96

Q9H6K1
WVRAVDGEWQIVGER

IGSF3

516

O75054
AAGLRWWQTAVVDGS

IGSF5

21

Q9NSI5
WEGLNLISRQWRGKS

BPIFC

491

Q8NFQ6
QWVRDKVGEQGLWAL

SDR9C7

91

Q8NEX9
SWRKLGLITGAWSVV

FFAR1

256

O14842
LADTPVQGGVWRIKW

DPH7

276

Q9BTV6
AVGIKLLWVAVIGDW

G6PC1

56

P35575
AGWIGKLRWERTLGA

HSD17B4

241

P51659
RLNWAVDRTGKWQEL

B3GALNT2

386

Q8NCR0
QVLKGTGDWWLARSL

BLK

86

P51451
GQALLKVWGRGWQAE

CPAMD8

96

Q8IZJ3
WWEGELQARGKKRQI

ITSN1

1111

Q15811
ELWKGRWQGNDIVVK

ILK

206

Q13418
KLTGSGELWWQAERA

CD4

231

P01730
QGRVAHLIEWKGWSK

FAM131A

126

Q6UXB0
GISWKDEARVVKWAL

ABCA2

2156

Q9BZC7
WIGIRKNNKTWTWVG

SELP

91

P16109
AAVKIQAWWRGTLVR

IQCF2

46

Q8IXL9
WAWKENFLEVGTLER

KIRREL1

426

Q96J84
LGGIWSVGQRIWQRD

COPS8

71

Q99627
TIWRWQEGAKIASRA

EML5

1496

Q05BV3
LLDVGASAWALERWK

GYS1

116

P13807
ALVLVWESGLAEVWG

HPS6

91

Q86YV9
WVKNQVGEKGLWGLI

DHRS9

96

Q9BPW9
GLIEKDTNGEVLWVW

DENND10

16

Q8TCE6
KWVKEWAGQVVITAS

DNAH2

1641

Q9P225
VKWEGVWRELGCLSR

SAMM50

226

Q9Y512
VVTVEVRGNWQRWLK

SDK1

1851

Q7Z5N4
WIPDGRGRWVKDENV

SCNM1

201

Q9BWG6
LWVWGRRVIQTMGKD

SLC20A1

576

Q8WUM9
VSVGWLRSKKAVDWR

SLC20A1

631

Q8WUM9
FWKRVRIGLEDIWNS

MENT

311

Q9BUN1
NLITGIEVIDEGWWR

DBNL

396

Q9UJU6
DEGWWTGQLNQRVGI

MAP3K9

91

P80192
KQVIFEEGSWGRWVQ

DGAT2

286

Q96PD7
LVVSGRVVAATEGWW

FUZ

181

Q9BT04
LGSVWKIRVWHDNKG

PKD1

3176

P98161
QLADWARKWRGTVEK

PACSIN3

56

Q9UKS6
VGMRVVRGVDWKWGQ

MIB2

11

Q96AX9
VRQLWDGTGVVKRWA

IL4I1

431

Q96RQ9
QWVCVLLLVVSWVGG

OR4A4P

136

Q8NGN8
LWEGQDVLARWTDGL

PHF1

31

O43189
AKVWGEVGRWLVIAL

PEX16

101

Q9Y5Y5
AGRRLWWLDLKSGAQ

HPX

376

P02790
VGIWAAWRTKNSGSA

SLC5A7

21

Q9GZV3
QGNGDLKRKWTWAVE

USP9X

2406

Q93008
RKLTWFVNEGLVDGW

EPRS1

436

P07814
DQCWVTGWGAIIRKE

PRSS29P

191

A6NIE9
SILISNGSRIKGWWV

TMEM120B

176

A0PK00
ILINNGSRIKGWWVF

TMEM120A

181

Q9BXJ8
ARWISKERAWTLGGV

TDRD9

196

Q8NDG6
WQEGKTWKAIRVDLV

DNTT

421

P04053
KIGFEWAAAIQGLWA

SLC18B1

401

Q6NT16
KSGNVWSLGVTIWEL

AATK

316

Q6ZMQ8
FVLAARLWGGSQLWA

LGI4

281

Q8N135
AWLQCQGGRELTWLK

PLEKHG4

391

Q58EX7
DGVWRVLWKDRAQDT

PNMA8B

86

Q9ULN7
ITNIRKEDGGWWEGQ

SH3KBP1

26

Q96B97
VDTTQAPGKVWWRLR

SCN5A

1181

Q14524
ADWIGLESRKSLWGQ

SBNO2

521

Q9Y2G9
PGKTALATREQVQWW

POLH

326

Q9Y253
QVSTEEGKGKIWWNL

SCN3A

1181

Q9NY46
LWASAQDVWNTRGRK

SLC25A53

251

Q5H9E4
DWLGVSRQLRTKAWN

PMEL

31

P40967
FAIIVGRGIRKWWQA

OMA1

161

Q96E52
WAAFTIWNAGKQGRR

B3GNTL1

261

Q67FW5
EKRGWLSLRLWSVAG

CLEC6A

11

Q6EIG7
EEWRRLGVQQSLGWV

CKS2

41

P33552
IDKIARWQVSIVGWE

SPATA13

431

Q96N96
RWQVSIVGWEGLDIL

SPATA13

436

Q96N96
WDEILKGEVQSIRWI

XIRP2

391

A4UGR9
GRWILAGVLSWEKAC

PRSS45P

196

Q7RTY3
DQVRLLWKDSRNVGW

THBS4

861

P35443
LIGNGSLVVWSFREW

TAS2R5

21

Q9NYW4
NAGVLTVRDAGSWWL

STK19

276

P49842
EWVAWRLLGKAGVLL

TXNDC16

291

Q9P2K2
VAGGQWKDTSRATLW

nan

256

Q6ZTK2
RATLWKWEGVLNLDS

nan

266

Q6ZTK2
WAWGEKGVLSNISAL

TSPAN17

41

Q96FV3
RNVSWASVLGKIWDS

ZNF555

76

Q8NEP9
NWKVCVLLAVALWTG

OR4E1

141

P0C645
AGACGLWVEEKEQWL

SPTBN2

861

O15020
WKFVLVENGGVTRWE

STBD1

321

O95210
RVDKWWGNRKELATV

RPL9

56

P32969
ELSWWVNGKEVHSGV

TRBC1

41

P01850
VAWLAEVLLWVGGSV

PLCH2

16

O75038
KVWWGQLSVDNGLWR

TRPM2

741

O94759
VLGVVFGKNDVWFWV

SIDT1

616

Q9NXL6
LWATLWEGQALVREG

TECPR1

256

Q7Z6L1
RWKGQLVESVGWNKA

VPS18

136

Q9P253
TTGDLDGWLKIWNIE

WDR49

436

Q8IV35
QWSVSEGRWIKIGDV

PLAA

366

Q9Y263
TVTEVGWDGLRLNWT

TNC

1081

P24821
LAAGQLLWWKGDVDQ

WDFY4

121

Q6ZS81
AEEGRWPWQVSVRTK

PRSS42P

86

Q7Z5A4
NKGLIWDTMVGTVWI

UNC13B

66

O14795
LQGNGDLKRKWTWAV

USP9Y

2406

O00507
VWLWVSLAKAGSNRR

UNQ9370/PRO34162

41

Q6UXP9
SLCWKDNVTLIIGWG

VPS41

221

P49754
AVSWRAVSWGLGLQF

SLC28A1

201

O00337
RLAGAEEWVGDRKQW

SLC28A1

511

O00337
EEWVGDRKQWISVRA

SLC28A1

516

O00337
VWRKVDTVWVNVGGL

THUMPD3

461

Q9BV44
WDVKDINRVGKVWSE

WDR62

386

O43379
ILQLEQGKELWWEGR

ZNF705B

56

P0CI00
VWWGIIESFLKERQG

TMEM245

406

Q9H330
IGLWAWNEKGVLSNI

TSPAN5

36

P62079
GVWAVRLAWGFVSAL

TRIM10

401

Q9UDY6
KIWEWLVGVACRQTG

ZZEF1

2826

O43149
ELSWWVNGKEVHSGV

TRBC2

41

A0A5B9
VSRWVEGRGVKWSAE

TRMT12

111

Q53H54
VGLWAWSEKGVLSDL

TSPAN14

36

Q8NG11
VWAALAVGLELWAAA

TNFRSF1B

6

P20333
GATGFLEWWVIELQE

PIEZO1

2396

Q92508
QRRAWATVGLVWAAA

TBXA2R

146

P21731
VGLRWWNQIDEDGKS

TVP23A

86

A6NH52
WKGSVAILQQWSARG

TGM7

256

Q96PF1
RFWSWVGQANDIGLL

PRSS50

196

Q9UI38
WEVVVGSKSDWRLGV

TRIM50

351

Q86XT4
WSCLQKQAAWGRSVV

SLC36A4

141

Q6YBV0
QIGGERWVWNIILTT

TM9SF1

366

O15321
LWLQLDWVSRGESVG

TRAV13-2

11

A0A0B4J235
TGKLWATVVGLAWLE

VWA5B1

1141

Q5TIE3
LAAWEEWLLVGTKQG

VPS39

21

Q96JC1
AGWLQLLSRWDKLDV

ZSWIM4

356

Q9H7M6
KTGQAINIASRWIWD

DYNLT2

156

Q8IZS6
QVIEELGGWRISGKW

KEL

171

P23276
ALVRWWNGIGAVLDF

MYORG

421

Q6NSJ0
WDGIAAKINGITSWK

MYPOP

56

Q86VE0