Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEE POTEF POTEKP POTEI	1.80e-08	11	56	4	GO:0098973
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	SPTBN4 POTEE ANK3 POTEF MYOM2 POTEKP POTEI	7.49e-08	130	56	7	GO:0005200
GeneOntologyMolecularFunction	structural constituent of postsynapse	POTEE POTEF POTEKP POTEI	1.88e-06	32	56	4	GO:0099186
GeneOntologyMolecularFunction	structural constituent of synapse	POTEE POTEF POTEKP POTEI	5.74e-06	42	56	4	GO:0098918
GeneOntologyMolecularFunction	helicase activity	IFIH1 CHD3 BTAF1 DNA2 DHX8	8.03e-05	158	56	5	GO:0004386
GeneOntologyMolecularFunction	phospholipid binding	SPTBN4 NF1 MARK1 DGKA WDFY3 SYT13 VPS13B	8.17e-04	548	56	7	GO:0005543
GeneOntologyBiologicalProcess	postsynaptic actin cytoskeleton organization	POTEE POTEF POTEKP POTEI	1.25e-06	31	54	4	GO:0098974
GeneOntologyBiologicalProcess	postsynaptic cytoskeleton organization	POTEE POTEF POTEKP POTEI	2.07e-06	35	54	4	GO:0099188
GeneOntologyBiologicalProcess	synapse organization	SPTBN4 POTEE NF1 PTPRD ANK3 MARK1 POTEF NTRK2 POTEKP POTEI	9.76e-06	685	54	10	GO:0050808
GeneOntologyBiologicalProcess	postsynapse organization	POTEE NF1 PTPRD MARK1 POTEF POTEKP POTEI	1.67e-05	313	54	7	GO:0099173
GeneOntologyBiologicalProcess	neuron development	SPTBN4 POTEE NF1 PTPRD ANK3 MARK1 POTEF NTRK2 TENM1 POTEKP POTEI DCC VPS13B	7.76e-05	1463	54	13	GO:0048666
GeneOntologyBiologicalProcess	neuron projection development	SPTBN4 POTEE NF1 PTPRD ANK3 MARK1 POTEF NTRK2 POTEKP POTEI DCC VPS13B	9.67e-05	1285	54	12	GO:0031175
GeneOntologyBiologicalProcess	axonogenesis	SPTBN4 POTEE ANK3 POTEF NTRK2 POTEKP POTEI DCC	1.05e-04	566	54	8	GO:0007409
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	SPTBN4 POTEE PTPRD ANK3 POTEF NTRK2 POTEKP POTEI DCC	1.27e-04	748	54	9	GO:0048667
GeneOntologyBiologicalProcess	cellular response to magnesium ion	ANK3 SLC41A1	1.86e-04	8	54	2	GO:0071286
GeneOntologyBiologicalProcess	clustering of voltage-gated sodium channels	SPTBN4 ANK3	1.86e-04	8	54	2	GO:0045162
GeneOntologyBiologicalProcess	cell junction organization	SPTBN4 POTEE NF1 PTPRD ANK3 MARK1 POTEF NTRK2 POTEKP POTEI	1.90e-04	974	54	10	GO:0034330
GeneOntologyBiologicalProcess	neuron projection morphogenesis	SPTBN4 POTEE PTPRD ANK3 POTEF NTRK2 POTEKP POTEI DCC	2.15e-04	802	54	9	GO:0048812
GeneOntologyBiologicalProcess	axon development	SPTBN4 POTEE ANK3 POTEF NTRK2 POTEKP POTEI DCC	2.48e-04	642	54	8	GO:0061564
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	SPTBN4 POTEE PTPRD ANK3 POTEF NTRK2 POTEKP POTEI DCC	2.51e-04	819	54	9	GO:0120039
GeneOntologyBiologicalProcess	cell projection morphogenesis	SPTBN4 POTEE PTPRD ANK3 POTEF NTRK2 POTEKP POTEI DCC	2.67e-04	826	54	9	GO:0048858
GeneOntologyCellularComponent	NuA4 histone acetyltransferase complex	POTEE POTEF POTEKP POTEI	1.57e-06	32	56	4	GO:0035267
GeneOntologyCellularComponent	H4/H2A histone acetyltransferase complex	POTEE POTEF POTEKP POTEI	1.57e-06	32	56	4	GO:0043189
GeneOntologyCellularComponent	H4 histone acetyltransferase complex	POTEE POTEF POTEKP POTEI	6.34e-06	45	56	4	GO:1902562
GeneOntologyCellularComponent	actin filament	SPTBN4 POTEE POTEF POTEKP POTEI	4.45e-05	146	56	5	GO:0005884
GeneOntologyCellularComponent	axon	SPTBN4 POTEE NF1 ANK3 POTEF NTRK2 POTEKP WDFY3 POTEI DCC	1.13e-04	891	56	10	GO:0030424
GeneOntologyCellularComponent	histone acetyltransferase complex	POTEE POTEF POTEKP POTEI	1.18e-04	94	56	4	GO:0000123
GeneOntologyCellularComponent	protein acetyltransferase complex	POTEE POTEF POTEKP POTEI	1.74e-04	104	56	4	GO:0031248
GeneOntologyCellularComponent	acetyltransferase complex	POTEE POTEF POTEKP POTEI	2.09e-04	109	56	4	GO:1902493
GeneOntologyCellularComponent	paranode region of axon	SPTBN4 ANK3	9.34e-04	17	56	2	GO:0033270
GeneOntologyCellularComponent	transferase complex	POTEE KLHDC1 POTEF POTEKP WDFY3 POTEI DNA2 PAPSS1 FBXL3	9.70e-04	963	56	9	GO:1990234
GeneOntologyCellularComponent	node of Ranvier	SPTBN4 ANK3	1.30e-03	20	56	2	GO:0033268
GeneOntologyCellularComponent	axon initial segment	SPTBN4 ANK3	2.73e-03	29	56	2	GO:0043194
GeneOntologyCellularComponent	M band	LRRC39 MYOM2	3.12e-03	31	56	2	GO:0031430
Domain	Actin_CS	POTEE POTEF POTEI	1.32e-05	16	55	3	IPR004001
Domain	ACTINS_2	POTEE POTEF POTEI	1.60e-05	17	55	3	PS00432
Domain	Actin/actin-like_CS	POTEE POTEF POTEI	1.91e-05	18	55	3	IPR020902
Domain	ACTINS_ACT_LIKE	POTEE POTEF POTEI	2.26e-05	19	55	3	PS01132
Domain	Actin	POTEE POTEF POTEI	1.02e-04	31	55	3	IPR004000
Domain	Actin	POTEE POTEF POTEI	1.02e-04	31	55	3	PF00022
Domain	ACTIN	POTEE POTEF POTEI	1.02e-04	31	55	3	SM00268
Domain	Helicase_C	IFIH1 CHD3 BTAF1 DHX8	2.77e-04	107	55	4	PF00271
Domain	HELICc	IFIH1 CHD3 BTAF1 DHX8	2.77e-04	107	55	4	SM00490
Domain	Helicase_C	IFIH1 CHD3 BTAF1 DHX8	2.87e-04	108	55	4	IPR001650
Domain	HELICASE_CTER	IFIH1 CHD3 BTAF1 DHX8	2.98e-04	109	55	4	PS51194
Domain	HELICASE_ATP_BIND_1	IFIH1 CHD3 BTAF1 DHX8	2.98e-04	109	55	4	PS51192
Domain	DEXDc	IFIH1 CHD3 BTAF1 DHX8	2.98e-04	109	55	4	SM00487
Domain	Helicase_ATP-bd	IFIH1 CHD3 BTAF1 DHX8	3.08e-04	110	55	4	IPR014001
Domain	Ank_2	POTEE ANK3 POTEF PPP1R13B POTEI	4.20e-04	215	55	5	PF12796
Domain	Ank	POTEE ANK3 POTEF PPP1R13B POTEI	5.49e-04	228	55	5	PF00023
Domain	IGc2	PTPRD NTRK2 MYOM2 DCC LILRA4	6.30e-04	235	55	5	SM00408
Domain	Ig_sub2	PTPRD NTRK2 MYOM2 DCC LILRA4	6.30e-04	235	55	5	IPR003598
Domain	-	POTEE ANK3 POTEF PPP1R13B POTEI	8.03e-04	248	55	5	1.25.40.20
Domain	ANK	POTEE ANK3 POTEF PPP1R13B POTEI	8.47e-04	251	55	5	SM00248
Domain	ANK_REPEAT	POTEE ANK3 POTEF PPP1R13B POTEI	8.78e-04	253	55	5	PS50088
Domain	Ankyrin_rpt-contain_dom	POTEE ANK3 POTEF PPP1R13B POTEI	8.94e-04	254	55	5	IPR020683
Domain	ANK_REP_REGION	POTEE ANK3 POTEF PPP1R13B POTEI	8.94e-04	254	55	5	PS50297
Domain	Ankyrin_rpt	POTEE ANK3 POTEF PPP1R13B POTEI	1.03e-03	262	55	5	IPR002110
Domain	fn3	IL12RB2 PTPRD MYOM2 DCC	1.32e-03	162	55	4	PF00041
Domain	-	IFIH1 SULT2A1 CHD3 AK9 BTAF1 DNA2 PAPSS1 DHX8	1.44e-03	746	55	8	3.40.50.300
Domain	Actinin_actin-bd_CS	SPTBN4 UTRN	2.07e-03	23	55	2	IPR001589
Domain	Spectrin	SPTBN4 UTRN	2.07e-03	23	55	2	PF00435
Domain	ACTININ_2	SPTBN4 UTRN	2.07e-03	23	55	2	PS00020
Domain	ACTININ_1	SPTBN4 UTRN	2.07e-03	23	55	2	PS00019
Domain	FN3	IL12RB2 PTPRD MYOM2 DCC	2.14e-03	185	55	4	SM00060
Domain	Ig_I-set	PTPRD NTRK2 MYOM2 DCC	2.36e-03	190	55	4	IPR013098
Domain	I-set	PTPRD NTRK2 MYOM2 DCC	2.36e-03	190	55	4	PF07679
Domain	-	LMAN2L LGALS9B WDFY3	2.76e-03	95	55	3	2.60.120.200
Domain	FN3	IL12RB2 PTPRD MYOM2 DCC	2.79e-03	199	55	4	PS50853
Domain	P-loop_NTPase	IFIH1 SULT2A1 CHD3 AK9 BTAF1 DNA2 PAPSS1 DHX8	3.20e-03	848	55	8	IPR027417
Domain	Spectrin_repeat	SPTBN4 UTRN	3.29e-03	29	55	2	IPR002017
Domain	FN3_dom	IL12RB2 PTPRD MYOM2 DCC	3.33e-03	209	55	4	IPR003961
Domain	SNF2_N	CHD3 BTAF1	3.99e-03	32	55	2	IPR000330
Domain	Spectrin/alpha-actinin	SPTBN4 UTRN	3.99e-03	32	55	2	IPR018159
Domain	SNF2_N	CHD3 BTAF1	3.99e-03	32	55	2	PF00176
Domain	SPEC	SPTBN4 UTRN	3.99e-03	32	55	2	SM00150
Domain	DNA/RNA_helicase_DEAH_CS	CHD3 DHX8	4.76e-03	35	55	2	IPR002464
Domain	DEAH_ATP_HELICASE	CHD3 DHX8	5.59e-03	38	55	2	PS00690
Domain	IG	PTPRD NTRK2 MYOM2 DCC LILRA4	7.84e-03	421	55	5	SM00409
Domain	Ig_sub	PTPRD NTRK2 MYOM2 DCC LILRA4	7.84e-03	421	55	5	IPR003599
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEE POTEF POTEKP POTEI	1.01e-08	15	59	4	16824795
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEE POTEKP POTEI	3.87e-07	9	59	3	16364570
Pubmed	Genetic association of LMAN2L gene in schizophrenia and bipolar disorder and its interaction with ANK3 gene polymorphism.	LMAN2L ANK3	2.83e-06	2	59	2	24914473
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEE POTEF	2.83e-06	2	59	2	19669888
Pubmed	Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex.	SPTBN4 ANK3	8.48e-06	3	59	2	33397944
Pubmed	Acetylated tau destabilizes the cytoskeleton in the axon initial segment and is mislocalized to the somatodendritic compartment.	SPTBN4 ANK3	8.48e-06	3	59	2	27356871
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEE POTEF	8.48e-06	3	59	2	17101985
Pubmed	βIV Spectrinopathies Cause Profound Intellectual Disability, Congenital Hypotonia, and Motor Axonal Neuropathy.	SPTBN4 ANK3	8.48e-06	3	59	2	29861105
Pubmed	TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response.	NF1 NTRK2	8.48e-06	3	59	2	29162814
Pubmed	[Beta]IV-spectrin regulates sodium channel clustering through ankyrin-G at axon initial segments and nodes of Ranvier.	SPTBN4 ANK3	8.48e-06	3	59	2	11807096
Pubmed	Axon Initial Segments Are Required for Efficient Motor Neuron Axon Regeneration and Functional Recovery of Synapses.	SPTBN4 ANK3	1.69e-05	4	59	2	36096668
Pubmed	Multifaceted role of the Topo IIIα-RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection.	RMI2 DNA2	1.69e-05	4	59	2	25200081
Pubmed	Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo.	SPTBN4 ANK3	1.69e-05	4	59	2	26187182
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SPTBN4 POTEE STXBP2 GSTK1 POTEF TENM1 DGKA CHD3 MYOM2 POTEI DCC	2.68e-05	1442	59	11	35575683
Pubmed	Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells.	SPTBN4 ANK3	2.82e-05	5	59	2	33303745
Pubmed	Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.	SPTBN4 ANK3	2.82e-05	5	59	2	18550753
Pubmed	A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier.	SPTBN4 ANK3	4.23e-05	6	59	2	20188654
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	SPTBN4 ANK3	4.23e-05	6	59	2	23728480
Pubmed	A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice.	SPTBN4 ANK3	4.23e-05	6	59	2	20877009
Pubmed	Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.	LMAN2L ANK3	4.23e-05	6	59	2	22182935
Pubmed	BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments.	SPTBN4 ANK3	4.23e-05	6	59	2	15381686
Pubmed	Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.	SPTBN4 POTEE PTPRD POTEF POTEKP	7.52e-05	256	59	5	24189400
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	ANK3 TENM1 PPP1R13B UTRN VPS13B	8.54e-05	263	59	5	34702444
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	POTEE POTEF CHD3 POTEKP POTEI	9.83e-05	271	59	5	32433965
Pubmed	Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project.	ANK3 NTRK2	1.01e-04	9	59	2	20877300
Pubmed	TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays.	SPTBN4 ANK3	1.01e-04	9	59	2	26671463
Pubmed	Ethanol sulfation by the human cytosolic sulfotransferases: a systematic analysis.	SULT2A1 PAPSS1	1.01e-04	9	59	2	23207770
Pubmed	Neurofascin 140 is an embryonic neuronal neurofascin isoform that promotes the assembly of the node of Ranvier.	SPTBN4 ANK3	1.01e-04	9	59	2	25653379
Pubmed	Generation of GABAergic and dopaminergic interneurons from endogenous embryonic olfactory bulb precursor cells.	SV2B NTRK2	1.26e-04	10	59	2	17038521
Pubmed	Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.	SV2B UTRN	1.54e-04	11	59	2	12403715
Pubmed	Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin.	ANK3 UTRN	1.54e-04	11	59	2	10995443
Pubmed	Widespread Differential Expression of Coding Region and 3' UTR Sequences in Neurons and Other Tissues.	SOX12 DCC	1.85e-04	12	59	2	26687222
Pubmed	Genetically engineered mouse models of brain cancer and the promise of preclinical testing.	NF1 PTCH2	1.85e-04	12	59	2	19076778
Pubmed	Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain.	WDFY3 DCC	2.54e-04	14	59	2	27648578
Pubmed	CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.	NTRK2 DCC	2.93e-04	15	59	2	26503042
Pubmed	Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.	ZNF254 ZNF208	2.93e-04	15	59	2	15885501
Pubmed	Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/β-catenin, and mTOR signaling during corticogenesis.	NF1 ANK3	4.25e-04	18	59	2	33323119
Pubmed	Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.	AK9 DCC	4.25e-04	18	59	2	20602751
Pubmed	Defective neuromuscular synaptogenesis in agrin-deficient mutant mice.	SV2B UTRN	4.25e-04	18	59	2	8653788
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	SPTBN4 POTEE MAN2A1 PTPRD STXBP2 POTEF POTEKP POTEI	4.32e-04	1070	59	8	23533145
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ANK3 MARK1 ZNF254 DGKA CHD3 DNA2 UTRN VPS13B	4.70e-04	1084	59	8	11544199
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	POTEE POTEF POTEI	5.92e-04	96	59	3	23580065
Pubmed	Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein.	ANK3 ADAM23 TENM1	6.29e-04	98	59	3	23898208
Pubmed	The interaction between ubiquitin C-terminal hydrolase 37 and glucose-regulated protein 78 in hepatocellular carcinoma.	POTEE POTEF POTEKP	6.67e-04	100	59	3	21800051
Pubmed	Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.	LMAN2L ANK3 NT5DC2	7.07e-04	102	59	3	21926972
Pubmed	ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization.	NTRK2 DCC	1.04e-03	28	59	2	36074819
Pubmed	Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.	ZNF254 ZNF208	1.12e-03	29	59	2	14563677
Pubmed	Genome-wide analysis of chromosomal alterations in patients with esophageal squamous cell carcinoma exposed to tobacco and betel quid from high-risk area in India.	NTRK2 DCC	1.19e-03	30	59	2	20083228
Pubmed	Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1.	NTRK2 DCC	1.36e-03	32	59	2	26758845
Pubmed	Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.	PTCH2 SYT13	1.36e-03	32	59	2	14973295
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	LMAN2L PTPRD CHD3 BTAF1	1.41e-03	285	59	4	32838362
Pubmed	Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states.	SOX12 DCC	1.44e-03	33	59	2	33951080
Pubmed	CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.	POTEE POTEF POTEKP POTEI	1.47e-03	288	59	4	31501420
Pubmed	Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study.	NTRK2 DCC	1.62e-03	35	59	2	23192594
Pubmed	Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.	ANK3 ADAM23	1.62e-03	35	59	2	22688191
Cytoband	19p12	ZNF708 ZNF676 ZNF254 ZNF724 ZNF208	1.19e-07	90	59	5	19p12
Cytoband	Ensembl 112 genes in cytogenetic band chr19p12	ZNF708 ZNF676 ZNF254 ZNF724 ZNF208	5.45e-07	122	59	5	chr19p12
Cytoband	2q21.1	POTEE POTEF POTEKP POTEI	9.91e-07	58	59	4	2q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr2q21	POTEE POTEF POTEKP POTEI	4.45e-05	151	59	4	chr2q21
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEE POTEF POTEKP POTEI	1.30e-08	13	39	4	685
GeneFamily	Ankyrin repeat domain containing	POTEE ANK3 POTEF PPP1R13B POTEI	1.64e-04	242	39	5	403
GeneFamily	Fibronectin type III domain containing	IL12RB2 PTPRD MYOM2 DCC	3.82e-04	160	39	4	555
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	PTPRD NTRK2 MYOM2 DCC	3.91e-04	161	39	4	593
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 TENM1 DGKA CHD3 BTAF1 UTRN	2.43e-07	197	59	6	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NF1 ANK3 HLCS WDFY3 UTRN VPS13B	2.57e-07	199	59	6	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KLHDC1 TENM1 ZNF683 SLC41A1 SYT13	1.61e-06	149	59	5	3378d0fe79de6d7879fd48717ded5027593c785f
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	ZNF708 MAN2A1 ANK3 DGKA UTRN	2.43e-06	162	59	5	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	LRRC39 ADAM23 PPP1R13B MYOM2 SLC41A1	4.91e-06	187	59	5	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	LRRC39 ANK3 ADAM23 PPP1R13B MYOM2	5.17e-06	189	59	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 DGKA BTAF1 UTRN VPS13B	5.72e-06	193	59	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NF1 PTPRD ANK3 WDFY3 VPS13B	6.48e-06	198	59	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tfh\|lymph-node_spleen / Manually curated celltypes from each tissue	MAN2A1 ANK3 GSTK1 ADAM23 DGKA	6.48e-06	198	59	5	fbdd37ca3d4b61f266bf6146662cb300ef67b850
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 TENM1 BTAF1 UTRN VPS13B	6.64e-06	199	59	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	COVID_vent-Lymphocytic-ILC\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IL12RB2 FUT11 ZNF683 MYOM2 UTRN	6.64e-06	199	59	5	e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCell	COVID-19_Moderate-NK\|World / disease group, cell group and cell class	IL12RB2 FUT11 LGALS9B MYOM2 UTRN	6.64e-06	199	59	5	c41b67b760831c7d5e19fabcc932a056dc560f93
ToppCell	COVID_vent-Lymphocytic-ILC-NK_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IL12RB2 FUT11 ZNF683 MYOM2 UTRN	6.64e-06	199	59	5	5f914962e2572b0c6372465b81b7496fa663d93c
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	SPTBN4 SV2B NTRK2 TENM1 SYT13	6.80e-06	200	59	5	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	SPTBN4 SV2B NTRK2 TENM1 SYT13	6.80e-06	200	59	5	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	droplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX12 ADAM23 SV2B PGBD1	6.32e-05	162	59	4	8a488ecd25ef41468c3c7766eb936dbc2f7665a9
ToppCell	Control-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SPTBN4 ANK3 CHD3 LILRA4	6.32e-05	162	59	4	aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 ZNF676 DCC SYT13	7.27e-05	168	59	4	17d46f993dc4ae22b8087808582aba77f5c61892
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SPTBN4 SV2B POTEI SYT13	7.44e-05	169	59	4	b6b5bb6408c1305a00719e1b88a5e1202081faf3
ToppCell	ASK454-Immune-NK_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	FUT11 LGALS9B ZNF683 MYOM2	7.61e-05	170	59	4	84705434234bf2fbb5256bd5a1f6ab54c01c5a51
ToppCell	ASK454-Immune-NK_cell\|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq	FUT11 LGALS9B ZNF683 MYOM2	7.97e-05	172	59	4	c9e738c3540ee09b08805b1cdb66b4a0d9d40d33
ToppCell	TCGA-Brain-Primary_Tumor-Glioblastoma-Primary_GBM-11\|TCGA-Brain / Sample_Type by Project: Shred V9	POTEE POTEF POTEI	8.04e-05	63	59	3	d7dc1356a60cb527fe668328d5375f352239d911
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 LGALS9B ZNF208 MYOM2	8.15e-05	173	59	4	5295ed31648abf8edff214cf67cd4769f20f9e6d
ToppCell	facs-BAT-Fat-18m-Lymphocytic-T_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHDC1 RMI2 DGKA CHD3	8.52e-05	175	59	4	bf1ef77d5fed2135ac83a4f7e445ab59d1538696
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN4 POTEE POTEI SYT13	8.52e-05	175	59	4	182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTPRD NT5DC2 AADACL2 RMI2	8.71e-05	176	59	4	d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-mature_NK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	IL12RB2 FUT11 LGALS9B ZNF683	8.90e-05	177	59	4	0f2616a81f8fbede77c860b2126e3fa826672da3
ToppCell	Severe-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK3 CHD3 MYOM2 LILRA4	9.10e-05	178	59	4	b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCell	5'-Adult-LymphNode-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL12RB2 RMI2 ZNF724 ZNF208	9.50e-05	180	59	4	cc974ac352ef2adc953fb5f325880e5857595889
ToppCell	Epithelial-lung_neuroendocrine_cell_(PNEC)\|World / Lineage, Cell type, age group and donor	SPTBN4 SV2B POTEI SYT13	9.91e-05	182	59	4	57bf4ffb304324e2e392e196336a530d9f78fe0d
ToppCell	COVID-19_Mild-gd_T\|COVID-19_Mild / Disease condition and Cell class	AADACL2 ZNF683 MYOM2 UTRN	1.01e-04	183	59	4	f593a89b0aa8fffdfa403769916facfd30358521
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 TENM1 DGKA CHD3	1.01e-04	183	59	4	f2ef110bf29b1a8276ef216238363e542db262c1
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD TENM1 MYOM2 DCC	1.03e-04	184	59	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD TENM1 MYOM2 DCC	1.03e-04	184	59	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRD TENM1 MYOM2 DCC	1.03e-04	184	59	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	COVID-CD4-naive_CD4\|COVID / Condition, Cell_class and T cell subcluster	ANK3 GSTK1 TENM1 DGKA	1.03e-04	184	59	4	00db55970d336a301035efe43a4ab4db62627f38
ToppCell	Control-Lymphocyte-T_NK-CD4_TCM\|Control / Disease, Lineage and Cell Type	ANK3 GSTK1 ADAM23 DGKA	1.10e-04	187	59	4	1de80f40f753b31aed1fac9f3ff8a2ee6c755eec
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 GSTK1 ADAM23 NTRK2	1.10e-04	187	59	4	e1d6c1194476cf26969e405b0951796fed519f44
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	LRRC39 ADAM23 PPP1R13B MYOM2	1.12e-04	188	59	4	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 GSTK1 ADAM23 DGKA	1.12e-04	188	59	4	fe08277d5aa693a2e12786738d12ec6390e8d13d
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|368C / Donor, Lineage, Cell class and subclass (all cells)	ZNF708 HLCS AK9 MYOM2	1.15e-04	189	59	4	610d7cc1fc923dbd67d3b71f94d529a658982f87
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAN2A1 ANK3 ADAM23 NT5DC2	1.15e-04	189	59	4	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma\|TCGA-Lung / Sample_Type by Project: Shred V9	ADAM23 MARK1 NTRK2 DGKA	1.15e-04	189	59	4	aa4f7d7a5196e5ae481ebc2549de8e3f0ef6e6be
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL12RB2 ANK3 DGKA UTRN	1.17e-04	190	59	4	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	LRRC39 ADAM23 PPP1R13B MYOM2	1.17e-04	190	59	4	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	10x5'v1-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	IL12RB2 ANK3 LGALS9B ZNF683	1.17e-04	190	59	4	251d50a77e5118a9ad19ea01a7c7c862230ed63c
ToppCell	Severe-Lymphoid-NK-Treg\|Severe / Condition, Lineage, Cell class and cell subclass	FUT11 ZNF254 PGBD1 SLC41A1	1.17e-04	190	59	4	e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SPTBN4 SV2B TENM1 POTEI	1.17e-04	190	59	4	b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	LRRC39 ANK3 PPP1R13B MYOM2	1.19e-04	191	59	4	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	COVID-19_Moderate-CD4+_Tcm\|World / disease group, cell group and cell class	ANK3 GSTK1 ADAM23 DGKA	1.22e-04	192	59	4	5f94310f1470487816fce697ffcdc2627fc66878
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	LRRC39 ANK3 PPP1R13B MYOM2	1.22e-04	192	59	4	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	MAN2A1 ANK3 DGKA BTAF1	1.22e-04	192	59	4	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	Control-B_intermediate-10\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SPTBN4 ANK3 CHD3 LILRA4	1.22e-04	192	59	4	224bd958369ba8fa0d7be2126f7dc61c9f6ac19d
ToppCell	Healthy_donor-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	ANK3 GSTK1 ADAM23 DGKA	1.22e-04	192	59	4	1603903454ba6bf65c8e13ede620e0b1e8fbd7ec
ToppCell	background-NK_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	IL12RB2 PTPRD MYOM2 UTRN	1.24e-04	193	59	4	f8d6eff1e04926f85d265ec39fe66897fe29574d
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	MAN2A1 WDFY3 UTRN VPS13B	1.24e-04	193	59	4	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 GSTK1 ADAM23 DGKA	1.24e-04	193	59	4	194b49c152e3e3f599068ec88a7f0af6427b743a
ToppCell	COVID-19-kidney-CD-PC\|kidney / Disease (COVID-19 only), tissue and cell type	ZNF676 ANK3 ADAM23 ZNF208	1.24e-04	193	59	4	738689d009e4b118d7ce3171a207294b95cbe78b
ToppCell	COVID-19_Mild-CD4+_Tcm\|COVID-19_Mild / Disease condition and Cell class	ANK3 GSTK1 ADAM23 DGKA	1.27e-04	194	59	4	3be2b1c81e668ffdf593ff41d3ba211c26d77671
ToppCell	Healthy-CD4+_Tcm\|Healthy / disease group, cell group and cell class	ANK3 GSTK1 ADAM23 DGKA	1.27e-04	194	59	4	85c2c4f6b87a50b67903770a2dc74da765757c6d
ToppCell	COVID-19_Moderate-CD4+_Tcm\|COVID-19_Moderate / disease group, cell group and cell class	ANK3 GSTK1 ADAM23 DGKA	1.27e-04	194	59	4	346ab9801366501453cedd3cb7cdfb63b7e7ddf6
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	ANK3 NTRK2 PPP1R13B MYOM2	1.27e-04	194	59	4	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 GSTK1 TENM1 DGKA	1.27e-04	194	59	4	a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PTPRD STXBP2 NTRK2 WDFY3	1.29e-04	195	59	4	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PTPRD STXBP2 NTRK2 WDFY3	1.29e-04	195	59	4	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	SOX12 ANK3 DGKA CHD3	1.29e-04	195	59	4	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ZNF683 CHD3 MYOM2 UTRN	1.32e-04	196	59	4	418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NTRK2 POTEI HSPA12B SYT13	1.32e-04	196	59	4	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF683 CHD3 MYOM2 UTRN	1.32e-04	196	59	4	581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCell	Mild\|World / Disease group and Cell class	IFIH1 LGALS9B ZNF683 UTRN	1.32e-04	196	59	4	5e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCell	Mild-CD8+_T_activated\|World / Disease group and Cell class	IFIH1 LGALS9B ZNF683 UTRN	1.32e-04	196	59	4	79632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZNF683 CHD3 MYOM2 UTRN	1.32e-04	196	59	4	6beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCell	PBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ZNF683 CHD3 MYOM2 UTRN	1.32e-04	196	59	4	c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell	healthy_donor-Lymphocytic-T_cell-CD4+_Memory_T_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ANK3 GSTK1 ADAM23 DGKA	1.34e-04	197	59	4	c842d169dfce9af3ed7c01dc7e940c0bdd21388c
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANK3 TENM1 DGKA UTRN	1.34e-04	197	59	4	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast-(8)_Pericytes\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	STXBP2 NT5DC2 NTRK2 UTRN	1.34e-04	197	59	4	608328608cef82adc867a449216839622253d486
ToppCell	COVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	FUT11 ZNF683 CHD3 UTRN	1.34e-04	197	59	4	d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCell	COVID_vent-Lymphocytic-T_cell-CD4+_Memory_T_cell\|COVID_vent / Disease condition, Lineage, Cell class and subclass	ANK3 GSTK1 DGKA CHD3	1.37e-04	198	59	4	58f208b76cb0adcecdf632d92f92833a06f9bf71
ToppCell	Severe-B_intermediate-10\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	ANK3 CHD3 MYOM2 LILRA4	1.37e-04	198	59	4	dfae26c3513a82bb7cb8dadbfcea2a1f420b1bab
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	ANK3 GSTK1 DGKA CHD3	1.37e-04	198	59	4	2cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IL12RB2 FUT11 MYOM2 UTRN	1.40e-04	199	59	4	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	COVID-19_Moderate-NK\|COVID-19_Moderate / disease group, cell group and cell class	IL12RB2 FUT11 LGALS9B UTRN	1.40e-04	199	59	4	e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IL12RB2 FUT11 MYOM2 UTRN	1.40e-04	199	59	4	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	PTPRD ANK3 CHD3 SYT13	1.40e-04	199	59	4	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	PTPRD ANK3 CHD3 SYT13	1.40e-04	199	59	4	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 TENM1 PPP1R13B SYT13	1.42e-04	200	59	4	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	severe-NK\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FUT11 LGALS9B MYOM2 UTRN	1.42e-04	200	59	4	64e8a6c36e0c654b7b2416c9f19b9058215222b1
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	IFIH1 ANK3 DGKA CHD3	1.42e-04	200	59	4	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_Tcm\|Control / Disease, condition lineage and cell class	ANK3 GSTK1 ADAM23 DGKA	1.42e-04	200	59	4	f38f6afa3108473011763f9b6577aa5328686216
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated\|COVID-19_Mild / Disease, condition lineage and cell class	IL12RB2 FUT11 MYOM2 UTRN	1.42e-04	200	59	4	2281debd86e5d92e8fe0397aec9ef670800f7471
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD4+_Tcm\|COVID-19_Convalescent / Disease, condition lineage and cell class	ANK3 GSTK1 ADAM23 DGKA	1.42e-04	200	59	4	99c5abfe96d791c60ae6021ab4201851ee4afc47
ToppCell	COVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T\|COVID-19_Severe / Disease, condition lineage and cell class	ZNF683 CHD3 MYOM2 UTRN	1.42e-04	200	59	4	f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-9\|TCGA-Breast / Sample_Type by Project: Shred V9	POTEE POTEF POTEI	2.32e-04	90	59	3	96e836c7a1df279ac812b7c3aa75e6b81b614244
Drug	heliotrine	PTPRD SULT2A1 TENM1 VPS13B	7.27e-06	48	59	4	ctd:C010178
Drug	Buflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; PC3; HT_HG-U133A	NF1 SV2B NTRK2 PTCH2 ZNF208 DCC	1.23e-05	198	59	6	4258_UP
Drug	senkirkine	PTPRD SULT2A1 TENM1 VPS13B	1.90e-05	61	59	4	ctd:C009238
Drug	Linuron	NF1 SULT2A1 NTRK2 MYOM2 DCC	2.04e-05	128	59	5	ctd:D008044
Drug	Pyrrolizidine Alkaloids	PTPRD SULT2A1 TENM1 VPS13B	2.60e-05	66	59	4	ctd:D011763
Disease	Alcohol Related Birth Defect	ANK3 NTRK2	4.73e-05	6	53	2	C3146244
Disease	unipolar depression, bipolar disorder	LMAN2L ANK3 NTRK2 DCC	1.80e-04	156	53	4	EFO_0003761, MONDO_0004985
Disease	Manic Disorder	LMAN2L ANK3 NTRK2	2.87e-04	71	53	3	C0024713
Disease	Opioid use measurement	PTPRD MYOM2	3.27e-04	15	53	2	EFO_0009937
Disease	third ventricle volume measurement	PTPRD ANK3	3.27e-04	15	53	2	EFO_0010335
Disease	Manic	LMAN2L ANK3 NTRK2	3.78e-04	78	53	3	C0338831
Disease	Depression, Bipolar	LMAN2L ANK3 NTRK2	3.93e-04	79	53	3	C0005587
Disease	longitudinal BMI measurement	PTPRD NTRK2 ZNF208	4.38e-04	82	53	3	EFO_0005937
Disease	Cerebral Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0750935
Disease	Intracranial Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0750936
Disease	Pilocytic Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0334583
Disease	Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0280783
Disease	Diffuse Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0280785
Disease	Grade I Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0205768
Disease	Mixed oligoastrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0547065
Disease	Childhood Cerebral Astrocytoma	NF1 NTRK2	9.25e-04	25	53	2	C0338070
Disease	Gemistocytic astrocytoma	NF1 NTRK2	1.00e-03	26	53	2	C0334581
Disease	Protoplasmic astrocytoma	NF1 NTRK2	1.00e-03	26	53	2	C0334580
Disease	Fibrillary Astrocytoma	NF1 NTRK2	1.00e-03	26	53	2	C0334582
Disease	Anaplastic astrocytoma	NF1 NTRK2	1.08e-03	27	53	2	C0334579
Disease	brain aneurysm	PTPRD STXBP2 HLCS	1.11e-03	113	53	3	EFO_0003870
Disease	Intellectual Disability	NF1 LMAN2L CHD3 DCC FBXL3	1.23e-03	447	53	5	C3714756
Disease	androsterone sulfate measurement	SULT2A1 DCC	1.61e-03	33	53	2	EFO_0021117
Disease	bitter alcoholic beverage consumption measurement	NF1 PTPRD PPP1R13B	1.78e-03	133	53	3	EFO_0010092

Protein segments in the cluster

Peptide	Gene	Start	Entry
HWEEMLKNPRRQIAM	SYT13	406	Q7L8C5
MYVQEHRLWGLMDKP	FAM223B	1	A6NKX1
KDEALPWAMRRNQHM	AADACL2	256	Q6P093
MKNLTMERGDQWPFL	ADAM23	261	O75077
MEHGIITNWDDMEKI	POTEKP	71	Q9BYX7
MMYEHLQKWGPRREE	PPP1R13B	61	Q96KQ4
MEHGIITNWDDMEKI	POTEF	771	A5A3E0
PDLWIHHEEMEMKNI	DCC	1151	P43146
VKLSIPSMMWEHAGR	LILRA4	81	P59901
WDLGSVTDILCHMMP	MAN2A1	336	Q16706
RWGPEERKMHMPFQK	LGALS9B	81	Q3B8N2
PTGMLDVWYMKRHID	IL12RB2	321	Q99665
LNMPALEWLDMGSNK	LRRC39	196	Q96DD0
RDPLMQWLGKHVDSE	HLCS	396	P50747
MYVQEHRLWGLMDKP	FAM223A	1	Q8IWN6
LEMTLKDDGQHMWRP	DGKA	196	P23743
HLTIMMDIDGKHEWR	LMAN2L	221	Q9H0V9
DPEAIHMMRKWEGGD	HSPA12B	81	Q96MM6
MEHGIITNWDDMEKI	POTEE	771	Q6S8J3
DDVPLMWRMKQHAAV	PAPSS1	461	O43252
EMAVKLPHLWDAMVG	BTAF1	1041	O14981
EVSKHLGRVWFPDMM	FBXL3	411	Q9UKT7
EHINGRWSMPELMPD	CHD3	1506	Q12873
NDYMTEKLWRPMHLG	FUT11	286	Q495W5
DRMELLAHLLGEKWM	GSTK1	201	Q9Y2Q3
QAWGTMMVHKGLDLP	IFIH1	966	Q9BYX4
PKHAMWMRFTEDRLD	ANK3	2551	Q12955
SLEQIMKDRWMNVGH	MARK1	301	Q9P0L2
IDSGLWRMHLMEGEL	KLHDC1	51	Q8N7A1
WRMHLMEGELPASMS	KLHDC1	56	Q8N7A1
HQNIWLMPASEMEKS	DNA2	461	P51530
AEMDSIPMGLNKHWV	DHX8	496	Q14562
GQPMLKDVMLADAQW	PTPRD	761	P23468
MLNWHLHKGMTAPDE	AK9	1461	Q5TCS8
KEFIDWMHLEPQSMV	UTRN	3036	P46939
KMTDLSDNPIHESMW	RMI2	121	Q96E14
PRFLLEMGKHDEAWM	SV2B	301	Q7L1I2
MHWQEELLLGGMARD	PTCH2	291	Q9Y6C5
SPDHALRMWIRGMKS	TENM1	116	Q9UKZ4
ANIGHMDTPKELWRM	SLC41A1	161	Q8IVJ1
MEHGIITNWDDMEKI	POTEI	771	P0CG38
HIHGWMPMREEKNFL	SULT2A1	166	Q06520
QWLRPEMHTKEQIME	PGBD1	71	Q96JS3
MLGCWQREPHMRKNI	NTRK2	786	Q16620
QGKEPWNMKRHEMVE	ZNF676	26	Q8N7Q3
LEQGKEPWNMERHEM	ZNF724	56	A8MTY0
PIGSHLDKWMLEMTE	WDFY3	2361	Q8IZQ1
SQHERRKIMDQWPDM	SOX12	51	O15370
RKIMDQWPDMHNAEI	SOX12	56	O15370
GEWKVLIMDHPSMRI	STXBP2	26	Q15833
MAIRNPLEWHCKQMD	NF1	2361	P21359
ELDGWIHEKMLMARD	SPTBN4	1316	Q9H254
MLLRAEWMKPFDSHA	SERPINA13P	191	Q6UXR4
DKGMRHMVGPDWRQL	NT5DC2	276	Q9H857
LEQGKEPWNMKRHEM	ZNF708	56	P17019
LEEGKESWNMKRHEM	ZNF208	56	O43345
VWKMLQSLGRPEVHM	VPS13B	3856	Q7Z7G8
GHDWDPTCMKMDEVL	TXNL4A	31	P83876
EQGKEPWNMKRHEMV	ZNF254	66	O75437
LLMMVNELGHPSARW	ZNF683	236	Q8IZ20
HMRIGGSEEMAWLQI	MYOM2	1276	P54296