Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1E2 AKR1D1 AKR1B1

1.73e-0514743GO:0004032
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1E2 AKR1D1 AKR1B1

1.34e-0427743GO:0008106
GeneOntologyMolecularFunctionphosphodiesterase I activity

ENPP2 ENPP3

1.35e-045742GO:0004528
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1E2 AKR1D1 AKR1B1

2.24e-0432743GO:0004033
GeneOntologyMolecularFunctionnucleoside triphosphate diphosphatase activity

ASMTL ENPP3

5.98e-0410742GO:0047429
MousePhenoprolonged RR interval

SLC29A3 TEX2 BRD3 UHRF2 IL33 FKBP4

1.68e-05139556MP:0010506
MousePhenoabnormal RR interval

SLC29A3 TEX2 BRD3 UHRF2 IL33 FKBP4

3.73e-05160556MP:0010504
DomainALDOKETO_REDUCTASE_1

AKR1E2 AKR1D1 AKR1B1

6.74e-0610733PS00798
DomainAldo/ket_reductase_CS

AKR1E2 AKR1D1 AKR1B1

6.74e-0610733IPR018170
DomainAldo/keto_reductase

AKR1E2 AKR1D1 AKR1B1

6.74e-0610733IPR020471
DomainALDOKETO_REDUCTASE_2

AKR1E2 AKR1D1 AKR1B1

6.74e-0610733PS00062
DomainALDOKETO_REDUCTASE_3

AKR1E2 AKR1D1 AKR1B1

6.74e-0610733PS00063
Domain-

AKR1E2 AKR1D1 AKR1B1

3.09e-05167333.20.20.100
DomainNADP_OxRdtase_dom

AKR1E2 AKR1D1 AKR1B1

3.75e-0517733IPR023210
DomainAldo_ket_red

AKR1E2 AKR1D1 AKR1B1

3.75e-0517733PF00248
DomainAldo/ket_red/Kv-b

AKR1E2 AKR1D1 AKR1B1

3.75e-0517733IPR001395
Domain-

TDRD15 RNF17

2.24e-0467322.40.50.90
DomainNUC

ENPP2 ENPP3

2.24e-046732SM00477
DomainEndonuclease_NS

ENPP2 ENPP3

2.24e-046732SM00892
DomainDNA/RNA_non-sp_Endonuclease

ENPP2 ENPP3

2.24e-046732IPR001604
DomainStaphylococal_nuclease_OB-fold

TDRD15 RNF17

2.24e-046732IPR016071
Domain-

ENPP2 ENPP3

2.24e-0467323.40.570.10
DomainEndonuclease_NS

ENPP2 ENPP3

2.24e-046732PF01223
DomainExtracellular_endonuc_su_A

ENPP2 ENPP3

2.24e-046732IPR020821
DomainE-NPP

ENPP2 ENPP3

3.12e-047732IPR024873
DomainRA

RAPH1 MYO10 SNX27

3.73e-0436733PF00788
DomainSomatomedin_B

ENPP2 ENPP3

4.16e-048732PF01033
DomainRA_dom

RAPH1 MYO10 SNX27

5.10e-0440733IPR000159
DomainSO

ENPP2 ENPP3

5.33e-049732SM00201
DomainSomatomedin_B_dom

ENPP2 ENPP3

6.64e-0410732IPR001212
DomainSMB_1

ENPP2 ENPP3

6.64e-0410732PS00524
DomainSMB_2

ENPP2 ENPP3

6.64e-0410732PS50958
DomainPhosphodiest

ENPP2 ENPP3

6.64e-0410732PF01663
DomainPhosphodiest/P_Trfase

ENPP2 ENPP3

6.64e-0410732IPR002591
DomainTUDOR

TDRD15 RNF17

1.33e-0314732PF00567
DomainPentatricopeptide_repeat

POLRMT PTCD3

3.61e-0323732IPR002885
DomainTUDOR

TDRD15 RNF17

3.61e-0323732PS50304
DomainTUDOR

TDRD15 RNF17

4.96e-0327732SM00333
DomainUbiquitin-rel_dom

RAPH1 PIK3C2A SNX27 UHRF2

5.85e-03184734IPR029071
DomainTudor

TDRD15 RNF17

6.11e-0330732IPR002999
DomainAlkaline_phosphatase_core

ENPP2 ENPP3

6.51e-0331732IPR017850
DomainAlkaline_Pase-like_a/b/a

ENPP2 ENPP3

6.51e-0331732IPR017849
Domain-

ENPP2 ENPP3

6.51e-03317323.40.720.10
DomainLRRNT

SLIT2 RXFP1 BGN

6.68e-0398733IPR000372
DomainLRRNT

SLIT2 RXFP1 BGN

6.68e-0398733SM00013
Pubmed

Network organization of the human autophagy system.

PIK3C2A SMC1A ATG2B LARS1 POLRMT EIF5B LTA4H FKBP4

4.71e-0643775820562859
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

BLMH HSPA4L SMC1A EIF3L ENAH LARS1 EIF5B LTA4H AKR1B1 PRRC2A FKBP4 PTCD3

6.12e-061149751235446349
Pubmed

LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.

LARS1 EIF5B PRRC2A

6.41e-061775337072811
Pubmed

ZEB1 represses biogenesis of circ-DOCK5 to facilitate metastasis in esophageal squamous cell carcinoma via a positive feedback loop with TGF-β.

DOCK5 ZEB1

1.37e-05375234216686
Pubmed

Androgen-receptor-interacting nuclear proteins.

RAD54L2 RNF17

1.37e-05375210961928
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

BLMH TLK2 GTSF1 SMC1A LARS1 EIF5B RAD54L2 MTREX UHRF2 PRRC2A FKBP4

2.38e-051103751134189442
Pubmed

p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.

POLRMT EIF5B CCDC77 PRRC2A ITIH5

2.50e-0515975530581152
Pubmed

Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.

RAPH1 ENAH

2.75e-05475215469845
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

BLMH UBN1 SPOUT1 PIK3C2A SMC1A EIF3L LARS1 POLRMT EIF5B SNX27 MTREX PTCD3

3.10e-051353751229467282
Pubmed

Genome-wide association study of periodontal pathogen colonization.

TTLL11 UHRF2 IL33

4.15e-053175322699663
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TLK2 ZEB1 UBN1 RAPH1 SMC1A RALGAPB EIF5B BRD3 PRRC2A

4.33e-0577475915302935
Pubmed

PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.

RAPH1 ENAH

4.57e-05575215642358
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

BLMH HSPA4L SMC1A EIF3L ENAH LARS1 POLRMT EIF5B MTREX AKR1B1 FKBP4 PTCD3

5.12e-051425751230948266
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RARRES1 ZNF608 RAPH1 HSPA4L EIF5B KRBA2 BRD3 RAD54L2 OR10G9 CCDC77 NEB RNF17

5.73e-051442751235575683
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

UBN1 SMC1A EIF3L EIF5B LTA4H BRD3 MTREX UHRF2 AKR1B1 FKBP4

6.33e-051014751032416067
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

BLMH SLIT2 PIK3C2A ENPP3 LTA4H NEB AKR1B1 PRRC2A FKBP4 BGN

6.43e-051016751019056867
Pubmed

Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis.

RAPH1 ENAH

6.84e-05675224076656
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

SLIT2 HSPA4L TEX2 EIF5B SNX27 PRRC2A KCNT1

7.56e-0547575731040226
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

SMC1A EIF3L LARS1 EIF5B AKR1B1 FKBP4 PTCD3

7.76e-0547775731300519
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

EIF3L POLRMT EIF5B LTA4H MTREX PRRC2A FKBP4 PTCD3

8.26e-0565375822586326
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

BLMH RAPH1 RALGAPB ENAH SNX27 SMPD4 BRD3 CCDC77 PRRC2A FKBP4

8.38e-051049751027880917
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

TLK2 HSPA4L SMC1A EIF3L LARS1 SMPD4 LTA4H MTREX AKR1B1 FKBP4 PTCD3

9.34e-051284751117353931
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1E2 AKR1D1

9.57e-05775212562828
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

CFAP47 HSPA4L SMC1A EIF3L LARS1 EIF5B FKBP4

9.65e-0549475726831064
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

UBN1 SPOUT1 HSPA4L EIF3L MTREX FKBP4

1.10e-0434975625665578
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TLK2 DOCK5 SLIT2 SMC1A EIF3L ENAH ATG2B LARS1 EIF5B SNX27 FAM117B

1.20e-041321751127173435
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

TLK2 UBN1 SMC1A RAD54L2 CCDC77

1.22e-0422275537071664
Pubmed

Robo4 is a vascular-specific receptor that inhibits endothelial migration.

SLIT2 ENAH

1.27e-04875212941633
Pubmed

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.

SLIT2 ENAH

1.27e-04875210892742
Pubmed

The telomeric protein AKTIP interacts with A- and B-type lamins and is involved in regulation of cellular senescence.

BLMH EIF3L LARS1

1.28e-044575327512140
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AGO4 ZNF608 TEX2 LARS1 SMPD4 MTREX KCNT1

1.47e-0452975714621295
Pubmed

DNA sequence and analysis of human chromosome 9.

SPOUT1 TTLL11 BRD3 UHRF2 KCNT1 IL33

1.51e-0437075615164053
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

HSD17B7 SMC1A EIF3L SNX27 LTA4H AKR1B1 PTCD3

1.56e-0453475735032548
Pubmed

Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation.

IL33 BGN

1.64e-04975224257755
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

HSPA4L SMC1A LARS1 POLRMT BRD3 PRRC2A

2.12e-0439475627248496
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

SLIT2 HSPA4L SMC1A EIF3L LARS1 MTREX PRRC2A

2.34e-0457175737167062
Pubmed

Human transcription factor protein interaction networks.

ZEB1 UBN1 ZNF608 HSPA4L SMC1A EIF3L LARS1 RAD54L2 PRRC2A FKBP4 PTCD3

2.37e-041429751135140242
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

UBN1 PIK3C2A HSPA4L EIF3L LARS1 POLRMT EIF5B SMPD4 MTREX PRRC2A PTCD3

2.53e-041440751130833792
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

HSPA4L POLRMT MTREX PRRC2A PTCD3

3.22e-0427475534244482
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

APIP FZD6 RAPH1 MYO10 TTLL11 RALGAPB LARS1 OSBPL9 SMPD4 CCDC77

3.28e-041242751030973865
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ZNF608 PIK3C2A HSPA4L SMC1A TTLL11 LARS1 EIF5B MTREX PRRC2A FKBP4

3.38e-041247751027684187
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

SMC1A EIF3L LARS1 EIF5B MTREX FKBP4 PTCD3

3.39e-0460775739147351
Pubmed

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2.

RAPH1 FAM117B

3.52e-041375211586298
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SPOUT1 SMC1A EIF3L LARS1 POLRMT EIF5B MTREX UHRF2 FKBP4 PTCD3

3.60e-041257751036526897
Pubmed

LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus.

EIF5B SNX27 PTCD3

4.00e-046675336398858
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

HSPA4L SMC1A EIF3L LARS1 EIF5B MTREX FKBP4

4.56e-0463875733239621
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

UBN1 ZNF608 ATG2B BRD3 CCDC77 AKR1B1 PTCD3

4.87e-0464575725281560
Pubmed

The deubiquitinase USP9X regulates FBW7 stability and suppresses colorectal cancer.

LARS1 EIF5B FKBP4

4.95e-047175329346117
Pubmed

Genetic loci that control the angiogenic response to basic fibroblast growth factor.

FZD6 ENPP2

5.40e-041675215226265
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

BLMH HSPA4L TTLL11 EIF3L LARS1 POLRMT EIF5B MTREX PRRC2A PTCD3

5.76e-041335751029229926
Pubmed

Tuba, a novel protein containing bin/amphiphysin/Rvs and Dbl homology domains, links dynamin to regulation of the actin cytoskeleton.

RAPH1 ENAH

6.11e-041775214506234
Pubmed

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.

SLIT2 SPOUT1 POLRMT EIF5B MTREX PRRC2A

6.23e-0448375636912080
Pubmed

Genome-wide analysis of BMI in adolescents and young adults reveals additional insight into the effects of genetic loci over the life course.

TNNI3K ZNF608

6.87e-041875223669352
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

RAPH1 HSPA4L ENAH LARS1 EIF5B FKBP4

7.31e-0449875636634849
Pubmed

The dynamic alterations of H2AX complex during DNA repair detected by a proteomic approach reveal the critical roles of Ca(2+)/calmodulin in the ionizing radiation-induced cell cycle arrest.

EIF3L PTCD3

7.66e-041975216522924
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

HSD17B7 EIF3L LARS1 POLRMT SNX27 MTREX FKBP4

8.15e-0470475729955894
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

FBXO5 HSPA4L SMC1A ATG2B LARS1 EIF5B PRRC2A

8.42e-0470875739231216
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

HSPA4L MYO10 OSBPL9 MTREX

8.87e-0419775420811636
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RAPH1 HSPA4L SMC1A EIF3L ENAH LARS1 EIF5B MTREX PRRC2A PTCD3

9.01e-041415751028515276
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RAPH1 ENAH ATG2B LARS1 EIF5B LTA4H PRRC2A FKBP4

9.05e-0493475833916271
Pubmed

Myosin-X recruits lamellipodin to filopodia tips.

RAPH1 PIK3C2A MYO10

9.57e-048975336861887
Pubmed

The scaffold protein KSR1, a novel therapeutic target for the treatment of Merlin-deficient tumors.

SMC1A EIF3L EIF5B FKBP4 PTCD3

9.73e-0435075526549023
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

BLMH SPOUT1 MYO10 SMC1A EIF3L LARS1 EIF5B SHC3

1.00e-0394975836574265
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DOCK5 CFAP47 SPOUT1 EIF3L LTA4H BRD3 RXFP1

1.05e-0373675729676528
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

FBXO5 HSPA4L MYO10 EIF3L EIF5B MTREX PRRC2A PTCD3

1.16e-0397175833306668
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

HSPA4L EIF3L LARS1 MTREX PRRC2A PTCD3

1.23e-0355175634728620
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

PIK3C2A HSPA4L TEX2 RALGAPB POLRMT EIF5B SMPD4 CCDC77 FKBP4 PTCD3

1.31e-031487751033957083
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PIK3C2A HSPA4L TEX2 ATG2B POLRMT OSBPL9 SMPD4 CCDC77 FKBP4 PTCD3

1.37e-031496751032877691
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

MYO10 EIF5B RAD54L2

1.38e-031017539872452
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

BLMH PIK3C2A MYO10 SMC1A EIF3L OSBPL9 SNX27 PRRC2A

1.44e-03100575819615732
Pubmed

Proteomic and Interactome Approaches Reveal PAK4, PHB-2, and 14-3-3η as Targets of Overactivated Cdc42 in Cellular Responses to Genomic Instability.

BLMH LARS1 EIF5B AKR1B1

1.45e-0322575431478661
Pubmed

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

GTSF1 ENPP2 OSBPL9 FKBP4

1.45e-0322575425277244
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

EIF3L LARS1 MTREX PTCD3

1.59e-0323175436597993
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

DOCK5 UBN1 SMC1A ENAH MTREX RNF17

1.62e-0358275620467437
Pubmed

Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure.

ZEB1 ENAH

1.67e-032875232005677
Pubmed

The Catalytically Inactive Mutation of the Ubiquitin-Conjugating Enzyme CDC34 Affects its Stability and Cell Proliferation.

HSPA4L SMC1A LARS1 FKBP4

1.75e-0323775429564676
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

SPOUT1 SMC1A EIF3L POLRMT EIF5B PRRC2A PTCD3

1.79e-0380775722681889
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

SMC1A EIF3L ENAH LARS1 POLRMT EIF5B PTCD3

1.81e-0380975732129710
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

BLMH TEX2 MTREX PRRC2A

1.95e-0324475429884807
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

AKR1E2 SLC29A3 ZEB1 TECTB ITIH5

2.06e-0341575516385451
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

MEIOC HSPA4L SMC1A EIF3L LARS1 EIF5B SMPD4 MTREX PTCD3

2.08e-03131875930463901
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZEB1 ZNF608 RAPH1 ATG2B POLRMT

2.12e-0341875534709266
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

SMC1A EIF3L LARS1 EIF5B MTREX PRRC2A

2.14e-0361575631048545
Pubmed

A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.

FBXO5 SMC1A LARS1 EIF5B LTA4H

2.14e-0341975528700943
GeneFamilyAldo-keto reductases

AKR1E2 AKR1D1 AKR1B1

6.86e-0615463399
GeneFamilyTudor domain containing

TDRD15 UHRF2 RNF17

1.13e-0437463780
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK5 SLIT2 RARRES1 MYO10 ENPP2 ENAH

9.35e-07194756b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DOCK5 SLIT2 RARRES1 MYO10 ENPP2 ENAH

9.64e-071957560e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell356C-Fibroblasts-Fibroblast-H-|356C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 RARRES1 IL33 ITIH5 BGN

9.56e-06168755b5d74500bdac0d680ce7eb7afa0b867b8d85e6a4
ToppCell356C-Fibroblasts-Fibroblast-H|356C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 RARRES1 IL33 ITIH5 BGN

9.56e-06168755838ce47d4958ba12047882f97925eddd02f081c7
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 RARRES1 ENPP2 ENAH BGN

2.16e-051997557b1b3b108d817fb3b50a710c3146b30bcf9c2f6b
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZEB1 ENPP2 AKR1B1 IL33 BGN

2.16e-051997550075bcc7d2a5031e76a24cb176e16ac998d846fd
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 RARRES1 ENPP2 ENAH BGN

2.16e-05199755f2ad641f36c577ff7019e88ad6b73ed7e46d8c74
ToppCellwk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLIT2 RARRES1 ENPP2 ENAH ITIH5

2.16e-051997556bce8e65859a35cfea1c210f9c9765952d492ed2
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ZEB1 AGO4 ZNF608 PIK3C2A ENPP2

2.21e-05200755dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 RARRES1 ENPP2 ENAH BGN

2.21e-05200755780d47f8eff630020dfae32218de495a7e9dbad6
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 RARRES1 ENPP2 ENAH BGN

2.21e-0520075528dd127787a57276253548d1f030814b1af64481
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GTSF1 MEIOC ATG2B UHRF2

1.26e-041527545adcdf93fd3ca066402aaaf308c363e4648f871d
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 ENPP3 AKR1D1 G6PC1

1.40e-04156754e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZEB1 HSPA4L ENPP2 ENAH

1.69e-04164754583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ibsp-Inhibitory_Gad1Gad2_Htr3a.Ibsp_(Interneuron,__(candidate_CGE-derived_7))|Hippocampus / BrainAtlas - Mouse McCarroll V32

GTSF1 TMPRSS9 ENPP3

1.72e-0464753c13a7edad4d52a955e2c2247139246522d9e4463
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ibsp-Inhibitory_Gad1Gad2_Htr3a.Ibsp_(Interneuron,__(candidate_CGE-derived_7))-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GTSF1 TMPRSS9 ENPP3

1.72e-0464753eefb4573ec4ff8efe602543ccbe555dbef1c4d54
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Ibsp|Hippocampus / BrainAtlas - Mouse McCarroll V32

GTSF1 TMPRSS9 ENPP3

1.72e-0464753fcc0f3fa0b462620d031aae810a01fadb7c01202
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GTSF1 LTA4H AKR1B1 ITIH5

1.85e-04168754eba865465feb0f42055bb8f98946050eeb03d177
ToppCell343B-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MGAT5 RARRES1 ATG2B IL33

2.17e-0417575478a86cac3e6c0d115c997d1c29ee0e24af54551f
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

SLIT2 RARRES1 IL33 BGN

2.21e-04176754510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|356C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 RARRES1 IL33 BGN

2.21e-04176754135d51d28a7ad2a67d5a6c49eb6e661f4beb66f5
ToppCell356C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SLIT2 RARRES1 IL33 BGN

2.21e-041767542287bd8382f41e36ebb0875a0133bada1ec81fa7
ToppCellBAL-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

DOCK5 AKR1E2 BRD3 PTCD3

2.21e-04176754f9b0c3ced391e7ebe6b242d3f12ba14741f88d22
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MGAT5 MYO10 TEX2 RXFP1

2.21e-04176754de746cdf2c777eec88cb03863e128e97ad6e8fb0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 MEIOC SYT17 ITIH5

2.26e-041777548e4005fad50e6f919da175f3b9ae58849dbd60b1
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZEB1 MYO10 ITIH5 BGN

2.31e-04178754185b44700f06ec58b3c09c80520502166c965fd6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 MYO10 SYT17 ITIH5

2.36e-04179754e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK5 FBXO5 AKR1D1 AKR1B1

2.41e-0418075412f3c4c4aa7fe03c0ef847bd4d4942c808015f5f
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC-NK_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK5 FBXO5 AKR1D1 AKR1B1

2.41e-041807541bc01bb76d0d3f8db74f9244436d3e6d6015ed5d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_ILC|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK5 FBXO5 AKR1D1 AKR1B1

2.41e-041807542a28fbfe10a340c8662c2c8be33792f41fc09088
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MGAT5 MYO10 TEX2 RXFP1

2.41e-041807547a9aa96fb8035020640cc7d3df0c41c730516c6f
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 IL33 ITIH5 BGN

2.46e-04181754269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 IL33 ITIH5 BGN

2.46e-04181754cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 IL33 ITIH5 BGN

2.46e-04181754c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 MYO10 SYT17 ITIH5

2.46e-0418175430729f0364f719c044712a51453e22dc2c1a232b
ToppCellCOVID-19-kidney-Podocyte|kidney / Disease (COVID-19 only), tissue and cell type

DOCK5 MGAT5 ITIH5 BGN

2.57e-04183754fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGAT5 SYT17 AKR1B1 ITIH5

2.62e-04184754a60802e11dcc5f932811260b08a95a32f60f6b19
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGAT5 SYT17 AKR1B1 ITIH5

2.62e-0418475439c230d32e4259bc784e0edfd9e2884c96898564
ToppCell3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MGAT5 SYT17 AKR1B1 ITIH5

2.62e-041847542a2fb691cc9414ef5b06c26239d2da03d6d7e5c2
ToppCellIPF-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

DOCK5 ZEB1 ENPP2 SHC3

2.68e-04185754ced17f69486591c3cbbdc852a3e82c3f3a4a30d7
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES1 ENPP2 IL33 BGN

2.68e-04185754eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES1 ENPP2 IL33 BGN

2.68e-04185754f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 MYO10 SYT17 ITIH5

2.68e-041857549438097e94219c1db922b8507e3a29106d32a923
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RARRES1 ENPP2 IL33 BGN

2.68e-04185754ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 MYO10 SYT17 ITIH5

2.73e-04186754a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APIP LTA4H AKR1B1 ITIH5

2.73e-04186754cb7df8da6478b96955f3ef1394a0655ec8061bba
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 MEIOC SYT17 ITIH5

2.79e-041877547b0168bdaa7c6c6b39878aff6a17f0943189a380
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZEB1 RARRES1 ENPP2 ENAH

2.79e-04187754c104fbfef2d0bef64077ac721edf2379fd59d547
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLIT2 HSPA4L ENPP2 ENPP3

2.79e-04187754acd305475f3609800af0d7bc68d83ef41228080b
ToppCellfacs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSD17B7 ZEB1 ENPP2 ITIH5

2.85e-04188754aa516273cdde53c8c0295f06830972388f890c97
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

ZEB1 ENPP2 RXFP1 IL33

2.85e-04188754eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SLIT2 ENPP2 ENAH BGN

2.85e-04188754ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellCOVID-19-Heart-Fib_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLIT2 ZEB1 RARRES1 IL33

2.85e-04188754fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

ZEB1 PIK3C2A RXFP1 IL33

2.85e-04188754d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLIT2 MYO10 SYT17 ITIH5

2.85e-04188754e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellfacs-Heart-RA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNNI3K RXFP1 IL33 BGN

2.90e-04189754e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 IL33 ITIH5 BGN

2.90e-041897541821ae4a6e37ee4c6308071883f3f447a7c53c53
ToppCellMesenchymal-myofibroblast_cell|World / Lineage, Cell type, age group and donor

ZEB1 RARRES1 ENPP2 ENAH

2.90e-0418975444e37f88137bb249933eb615235b2cf2ae7f3925
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 IL33 ITIH5 BGN

2.90e-041897541e4d7e8dc98b3d70351e6a6c2aaf9ca01f141b8f
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLIT2 MYO10 ENPP2 ITIH5

2.90e-04189754203c80030df08ae112f9ae4043709f455d87ce89
ToppCelldroplet-Pancreas-PANCREAS-30m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 IL33 ITIH5 BGN

2.90e-041897541dc415ed41815f4296dafd8cf7f3e014c44db1db
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ZEB1 SYT17 ENPP2 ENAH

2.96e-04190754d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZEB1 PIK3C2A RXFP1 IL33

2.96e-041907541caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellCOVID-19-lung-Artery_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZEB1 ENPP2 RXFP1 IL33

2.96e-0419075407b675befcd1d0a9c90cb17b5d22323468325d51
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

SLIT2 ENPP2 ENAH ITIH5

2.96e-0419075462a3ec1ae0829602b0569cc051210551644f1d46
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZEB1 ENPP2 RXFP1 IL33

2.96e-04190754f6c38d197fd9d69a4f97cb2e72cd4747984c1a86
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 IL33 ITIH5 BGN

2.96e-04190754ad0f5605db6b694445ec9bd5dc8d2d834358c0f9
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZEB1 ENPP2 RXFP1 IL33

3.02e-0419175450601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCellfacs-MAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLIT2 ENPP3 IL33 BGN

3.02e-04191754b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLIT2 RARRES1 MYO10 ENAH

3.02e-0419175408720998aa55131d7377c4c67c4c935865bd7d79
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 IL33 ITIH5 BGN

3.02e-0419175483d1915835df6f2eb23f87986d695e71398edb9d
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

APIP SLIT2 ENAH BGN

3.02e-04191754e7c605b56934d1383237c1f946dbccef25d91368
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 SMC1A IL33 ITIH5

3.02e-041917547d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB1 ENPP2 ITIH5 BGN

3.08e-04192754671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZEB1 FAM117B RXFP1 ITIH5

3.08e-04192754c618ede75dce3988c87a5b8f98d8e94e1dd66efd
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 IL33 ITIH5 BGN

3.08e-0419275411088878043a6ff95ba1970361256a82e434b80a
ToppCellControl-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

ENPP2 AKR1B1 IL33 BGN

3.08e-041927547e89b9125e8b85f6be85eeccef5c8644647ab0e1
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB1 ENPP2 ITIH5 BGN

3.08e-04192754840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP3 IL33 ITIH5 BGN

3.08e-04192754011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCellMesenchymal_cells-Ng2+_MSCs|World / Lineage and Cell class

SLIT2 RARRES1 RAPH1 BGN

3.08e-041927540703b8ec6960ff975ee5a2737054db67cab016b5
ToppCell390C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

APIP LTA4H AKR1B1 ITIH5

3.14e-04193754c9cf5a661294a947d06d53d18d47362c0e0b6ef5
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 IL33 ITIH5 BGN

3.14e-041937540a665531d581d4e3941e29d3f95569da8f166447
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZEB1 ZNF608 ENPP2 RXFP1

3.14e-041937546e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZEB1 PIK3C2A RXFP1 IL33

3.14e-041937549ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP2 IL33 ITIH5 BGN

3.14e-0419375424ce1f37cca655415410d2403a52d1ebb3332280
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RARRES1 MYO10 ENPP2 ENAH

3.21e-0419475428c5482da199bcee9e85258a88af453d9fdbd56a
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ENPP2 AKR1B1 IL33 BGN

3.21e-04194754582db7f7fa9aa08027ae18ed607945b5d1dc908a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC29A3 EIF3L LTA4H AKR1B1

3.21e-04194754b829a63b51b92507a53ffd0393bd9458b2b9440f
ToppCellEndothelial-A-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ZEB1 ENPP2 RXFP1 IL33

3.21e-04194754abea887dd472c1a0d572e690bc8914c1b94712ad
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

APIP LTA4H AKR1B1 ITIH5

3.21e-04194754412c2b8eb522da6c84f8b00d32d6f0bee555251f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK5 RARRES1 SYT17 BGN

3.21e-04194754fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellP15-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ENPP2 ENPP3 ITIH5 BGN

3.21e-041947545f04d21c4e2d36e74b6c5889aa97fd98f75a0973
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ENPP2 AKR1B1 IL33 BGN

3.21e-04194754bda89111386398a072b70e8153b2a762298a047a
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CFAP47 CCDC168 SHC3

3.21e-0479753cc17a013a4a57a99c404b10449ef61ce559631d1
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Unc5b_(Neuron.Gad1Gad2.Pvalb-Unc5b)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CFAP47 CCDC168 SHC3

3.21e-047975319fb2bc964589ea40e7b9f0809c641331c93dacd
ToppCellCOVID-19-Heart-Fib_1|Heart / Disease (COVID-19 only), tissue and cell type

SLIT2 RARRES1 IL33 ITIH5

3.27e-04195754f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FZD6 ENPP2 RXFP1 IL33

3.27e-04195754527a5a50d6e2cbbbd64d11609e5cde2e33f14797
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZEB1 ENPP2 ITIH5 BGN

3.27e-04195754223f5f07dc28fa13a09bb589884c58043c7928c7
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

SLIT2 MYO10 ENAH ITIH5

3.27e-04195754603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZEB1 ENPP2 RXFP1 IL33

3.27e-04195754023e3c97dd3696d74f002ff8da0c04d876c82aef
Drug11-keto-beta-boswellic acid

ENPP2 ENPP3 LTA4H

1.82e-068743CID006918114
DrugPdNP

BLMH ENPP2 ENPP3

9.21e-0613743CID000151930
Drugmannose-1-phosphate

BLMH MGAT5 ENPP2 ENPP3 AKR1B1 G6PC1

1.63e-05165746CID000000466
DrugCaptopril [62571-86-2]; Down 200; 17.2uM; PC3; HT_HG-U133A

SLIT2 ZEB1 UBN1 MYO10 SNX27 BRD3

2.58e-051797464585_DN
DrugRI-64

ENPP2 ENPP3

3.12e-053742CID000065758
DrugXe 4

ENPP3 FKBP4

3.12e-053742CID011269429
Drug4mupt

ENPP2 ENPP3

3.12e-053742CID000196156
Drugphenylphosphonic dichloride

ENPP2 ENPP3

3.12e-053742CID000069990
Drugquinovic acid

ENPP2 ENPP3

3.12e-053742CID000120678
DiseaseLiver Cirrhosis, Experimental

MGAT5 RARRES1 ENPP2 LTA4H AKR1B1 G6PC1 IL33 BGN

5.89e-04774728C0023893
Diseaseproliferative diabetic retinopathy (is_marker_for)

SLIT2 ENPP2

6.89e-0416722DOID:13207 (is_marker_for)
DiseaseMyeloid Leukemia

SMC1A ATG2B

8.76e-0418722C0023470
DiseaseLeukemia, Monocytic, Chronic

SMC1A ATG2B

8.76e-0418722C0023466
Diseaseresponse to gemcitabine

MGAT5 ITIH5

1.70e-0325722GO_0036272
Diseaseacute myocardial infarction (biomarker_via_orthology)

ZEB1 IL33

2.13e-0328722DOID:9408 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
QPVDAIKLNLPDYHK

BRD3

61

Q15059
CHPYFTQPKLLKFCQ

AKR1D1

196

P51857
KKYLHQLIAANPVLP

ARL9

106

Q6T311
TYFCKEPPHKVTILQ

CCDC77

161

Q9BR77
KYPHLPCLQVGQEQK

AGO4

311

Q9HCK5
QLACLKYPHLITKEP

RAD54L2

931

Q9Y4B4
QLSKVKFQHEVYPPC

ATG2B

1611

Q96BY7
LKYKPAVNQIECHPY

AKR1B1

176

P15121
KAPTDYCLVLKHPQI

RAPH1

461

Q70E73
KKPYNPILGEIFQCH

OSBPL9

451

Q96SU4
KFIQKVPIPCYLIAL

LTA4H

191

P09960
KYFQKDIAEPHIPCL

PTCD3

126

Q96EY7
FVILIHLYKKPAPFQ

ITIH5

806

Q86UX2
LVPSFDPKNKHCVFQ

MGAT5

691

Q09328
VHPNYHKEPFLQQLK

EIF3L

431

Q9Y262
PEKLLQCPYDKNHQI

GTSF1

11

Q8WW33
LNHFCKQLVKLYYPP

ASMTL

201

O95671
CPLYVQILKPENKFH

KCNT1

466

Q5JUK3
YCFKHPNCLPKILAS

PIK3C2A

901

O00443
QKLYISKNHLVEIPP

BGN

141

P21810
LYCQLIKQTNKVPHP

MYO10

1606

Q9HD67
IQECILPDSPLYHNK

SMPD4

161

Q9NXE4
QYHIPCPYQAKAKAR

FZD6

456

O60353
HKCEKPLPDQAFFVL

IL33

206

O95760
KPCVPHLLQKDSYYV

DOCK5

1276

Q9H7D0
NLSCRKPDQHFKPYL

ENPP3

426

O14638
YPNKNLLPVLHFEKV

FBXO5

186

Q9UKT4
IPYCLAQVLGQPHKK

G6PC1

341

P35575
KQLHEIPAFYCPDKN

FAM117B

486

Q6P1L5
HKKGCQVEFSYPPLI

AVL9

26

Q8NBF6
LFHQKPESLNPLIKY

HSD17B7

271

P56937
DKICLVNDPRPQHKY

BLMH

266

Q13867
HQVVINCAIPKGLKY

ENAH

56

Q8N8S7
LPCILHQLYIENPKK

CCDC168

3196

Q8NDH2
QIPPNAELKYELHLK

FKBP4

236

Q02790
YPKLHLPLKTLQCLF

POLRMT

386

O00411
IKNQCELLPVTYHFK

CFAP47

436

Q6ZTR5
NLTCKKPDQHFKPYL

ENPP2

411

Q13822
CPQYLRKAFFPKHQD

SPOUT1

151

Q5T280
YLTLCKQCHQKNPVP

KRBA2

231

Q6ZNG9
NQIQHYLCDAPPILK

OR10G9

171

Q8NGN4
KEHPRYLIPELCKQF

APIP

21

Q96GX9
CRYPEYVHPNKAKLN

MEIOC

326

A2RUB1
PLFVLCNYQPRVHLK

SLC29A3

391

Q9BZD2
HSNPYVKICLLPDQK

SYT17

226

Q9BSW7
PKNIHARFLKPSVCY

TDRD15

1201

B5MCY1
DKQPLQKPSHCTIYV

LARS1

926

Q9P2J5
HIAVFPCKIKILPQY

EIF5B

1086

O60841
HPVELKPFQDYQKLS

PRRC2A

2051

P48634
KQYLQCPTKIPALHD

SHC3

306

Q92529
APNKADVILVFCYPK

TECTB

21

Q96PL2
NALKYLNEIKPPIIH

TLK2

576

Q86UE8
LRFKPLTNQIECHPY

AKR1E2

186

Q96JD6
FTEKIPQCHLYPILL

RNF17

1266

Q9BXT8
NVAYHIYCLNPPLDK

UHRF2

366

Q96PU4
HLPSICLKQVFPKYA

TTLL11

616

Q8NHH1
FEKCLPPNLDLLKYN

ZNF684

136

Q5T5D7
LIFPENIHIQKKPYN

ZNF519

196

Q8TB69
EEYIHKPKYCLPFLQ

MTREX

641

P42285
PNCRYKEKHLNTPYI

RNASE8

116

Q8TDE3
KELDNFCNPIIYKPK

HSPA4L

776

O95757
KYIQPVCLPLAIQKF

TMPRSS9

606

Q7Z410
EPPHIKKALQYACGN

SMC1A

601

Q14683
NLIRKLPPDCFKNYH

RXFP1

136

Q9HBX9
LPPDCFKNYHDLQKL

RXFP1

141

Q9HBX9
KLAPNEFPHKLYIQN

SNX27

331

Q96L92
CQKPYFLKEIPIQDV

SLIT2

691

O94813
ELNQYPCLKHLPQIF

RALGAPB

321

Q86X10
INALPELKHYDLKQP

ZEB1

541

P37275
PQEQKVHLREKPYEC

ZNF480

191

Q8WV37
HKRCPEFFYPELVKN

UBN1

56

Q9NPG3
VLIDCPHPNCNKKYK

ZNF608

551

Q9ULD9
VPKILQAFKPYVDHQ

TEX2

876

Q8IWB9
LKHYKRPQDELPCNE

TNNI3K

401

Q59H18
PLKVKYHCQELQTPE

RARRES1

261

P49788
KFKCHIPADAPQFIQ

NEB

781

P20929