Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

BCL9L NCOA6 EP300 ARID1B DCC BCL9

7.07e-07303226GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

BCL9L NCOA6 EP300 ARID1B DCC BCL9

2.46e-05562226GO:0003712
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NCOA6 EP300

2.18e-0420222GO:0035259
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

NCOA6 EP300

2.40e-0421222GO:0042975
GeneOntologyMolecularFunctionbeta-catenin binding

BCL9L EP300 BCL9

3.00e-04120223GO:0008013
GeneOntologyMolecularFunctionchromatin binding

NCOA6 POLD1 EP300 ARID1B CHD7

1.07e-03739225GO:0003682
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

BCL9L NCOA6 EP300 ARID1B DCC BCL9

1.26e-031160226GO:0030674
GeneOntologyMolecularFunctionmolecular adaptor activity

BCL9L NCOA6 EP300 ARID1B DCC BCL9

2.81e-031356226GO:0060090
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

EP300 CHD7

3.74e-0383222GO:1990841
GeneOntologyMolecularFunctiondamaged DNA binding

POLD1 EP300

3.82e-0384222GO:0003684
GeneOntologyBiologicalProcessmyoblast differentiation

BCL9L XIRP1 ARID1B BCL9

1.21e-05136224GO:0045445
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

PBX3 BCL9L POU3F1 NCOA6 EP300 CHD7 PYGO1 BCL9

5.67e-051390228GO:0045944
GeneOntologyCellularComponenttranscription regulator complex

PBX3 BCL9L POU3F1 NCOA6 EP300 BCL9

2.65e-05596226GO:0005667
GeneOntologyCellularComponentbeta-catenin-TCF complex

BCL9L BCL9

8.19e-0513222GO:1990907
GeneOntologyCellularComponentnuclear protein-containing complex

BCL9L WDR33 NCOA6 SF3A2 POLD1 ARID1B BCL9

3.75e-041377227GO:0140513
HumanPhenoHereditary nonpolyposis colorectal carcinoma

POLD1 EP300 DCC

1.23e-053283HP:0006716
HumanPhenoAbnormality of the uterus

POLD1 EP300 ARID1B CHD7 DCC

1.52e-0525685HP:0000130
HumanPhenoDislocated radial head

EP300 ARID1B CHD7

6.08e-055483HP:0003083
HumanPhenoAbnormality of the radial head

EP300 ARID1B CHD7

7.15e-055783HP:0003995
HumanPhenoAbnormality of the humeroradial joint

EP300 ARID1B CHD7

9.21e-056283HP:0100744
HumanPhenoAbnormality of the larynx

POLD1 EP300 ARID1B CHD7 SEC31A DCC

1.08e-0466686HP:0001600
HumanPhenoDuodenal ulcer

EP300 ARID1B

1.41e-041282HP:0002588
HumanPhenoHypoplasia of the phalanges of the toes

EP300 ARID1B

1.41e-041282HP:0010746
HumanPhenoUterine neoplasm

POLD1 EP300 DCC

1.44e-047283HP:0010784
HumanPhenoGastrointestinal carcinoma

POLD1 EP300 DCC

1.63e-047583HP:0002672
HumanPhenoMalignant gastrointestinal tract tumors

POLD1 EP300 DCC

1.63e-047583HP:0006749
HumanPhenoAbnormal testis morphology

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

1.67e-04112987HP:0000035
HumanPhenoFemale reproductive system neoplasm

POLD1 EP300 DCC

1.69e-047683HP:0033020
HumanPhenoNon-obstructive azoospermia

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

1.70e-04113287HP:0011961
HumanPhenoAzoospermia

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

1.97e-04115787HP:0000027
HumanPhenoAbnormal stomach morphology

POLD1 EP300 ARID1B CHD7 SEC31A DCC

2.02e-0474286HP:0002577
HumanPhenoElbow dislocation

EP300 ARID1B CHD7

2.28e-048483HP:0003042
HumanPhenoAbnormal spermatogenesis

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

2.39e-04119087HP:0008669
HumanPhenoSquare face

EP300 CHD7

2.56e-041682HP:0000321
HumanPhenoAbnormal duodenum morphology

EP300 ARID1B CHD7

2.62e-048883HP:0002246
HumanPhenoAbnormal male internal genitalia morphology

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

3.20e-04124387HP:0000022
HumanPhenoUpper extremity joint dislocation

EP300 ARID1B CHD7

3.39e-049683HP:0030310
HumanPhenoNeoplasm of the stomach

POLD1 EP300 DCC

3.61e-049883HP:0006753
HumanPhenoFunctional abnormality of male internal genitalia

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

3.68e-04126987HP:0000025
HumanPhenoHypothalamic gonadotropin-releasing hormone deficiency

CHD7 DCC

4.47e-042182HP:0003164
HumanPhenoLocalized hirsutism

EP300 ARID1B

4.47e-042182HP:0009889
HumanPhenoAbnormal gonadotropin-releasing hormone concentration

CHD7 DCC

4.47e-042182HP:0500012
HumanPhenoAbnormal male reproductive system physiology

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

4.66e-04131487HP:0012874
HumanPhenoAbnormal male external genitalia morphology

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

5.03e-04132987HP:0000032
HumanPhenoAbnormal cheek morphology

EP300 ARID1B CHD7 PCLO

5.39e-0428284HP:0004426
HumanPhenoNeoplasm of the large intestine

POLD1 EP300 DCC

5.63e-0411483HP:0100834
HumanPhenoAbnormality of the voice

POLD1 ARID1B CHD7 SEC31A DCC

5.85e-0454585HP:0001608
HumanPhenoAbnormal external genitalia

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

6.22e-04137287HP:0000811
HumanPhenoPerimembranous ventricular septal defect

EP300 SEC31A

6.88e-042682HP:0011682
HumanPhenoUterine leiomyosarcoma

EP300 DCC

7.99e-042882HP:0002891
HumanPhenoLeiomyosarcoma

EP300 DCC

7.99e-042882HP:0100243
HumanPhenoNeoplasm of the gastrointestinal tract

POLD1 EP300 ARID1B DCC

8.03e-0431384HP:0007378
HumanPhenoLong eyelashes

EP300 ARID1B SEC31A

8.10e-0412983HP:0000527
HumanPhenoAbnormality of the male genitalia

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

8.49e-04143787HP:0010461
HumanPhenoSensorineural hearing impairment

POLD1 EP300 KIZ ARID1B CHD7 DCC

8.63e-0495886HP:0000407
HumanPhenoTransitional cell carcinoma of the bladder

EP300 DCC

9.81e-043182HP:0006740
HumanPhenoRenal neoplasm

POLD1 EP300 DCC

1.01e-0313983HP:0009726
HumanPhenoAplasia/Hypoplasia of toe

EP300 ARID1B CHD7

1.03e-0314083HP:0001991
HumanPhenoNeoplasm of the liver

POLD1 EP300 ARID1B

1.03e-0314083HP:0002896
HumanPhenoBimanual synkinesia

CHD7 DCC

1.05e-033282HP:0001335
HumanPhenoSynkinesis

CHD7 DCC

1.05e-033282HP:0034980
HumanPhenoAbnormal branching pattern of the aortic arch

EP300 CHD7

1.11e-033382HP:0011587
HumanPhenoBladder carcinoma

EP300 DCC

1.11e-033382HP:0002862
HumanPhenoUrinary tract neoplasm

POLD1 EP300 DCC

1.12e-0314483HP:0010786
HumanPhenoAbnormal internal genitalia

POLD1 EP300 KIZ ARID1B CHD7 SEC31A DCC

1.12e-03149887HP:0000812
HumanPhenoBladder neoplasm

EP300 DCC

1.18e-033482HP:0009725
HumanPhenoAspiration

EP300 SEC31A

1.18e-033482HP:0002835
HumanPhenoDelayed skeletal maturation

EP300 ARID1B CHD7 DCC

1.26e-0335284HP:0002750
HumanPhenoGenital neoplasm

POLD1 EP300 DCC

1.26e-0315083HP:0010787
HumanPhenoAplasia/Hypoplasia of the phalanges of the toes

EP300 ARID1B

1.32e-033682HP:0010173
HumanPhenoUnsteady gait

EP300 ARID1B CHD7 DCC

1.32e-0335784HP:0002317
HumanPhenoDyspareunia

CHD7 DCC

1.40e-033782HP:0030016
HumanPhenoAbnormal cerebral ventricle morphology

POLD1 EP300 ARID1B CHD7 SEC31A DCC

1.41e-03104686HP:0002118
HumanPhenoAgenesis of corpus callosum

EP300 ARID1B SEC31A DCC

1.44e-0336584HP:0001274
HumanPhenoAbnormal uterus morphology

POLD1 EP300 DCC

1.46e-0315883HP:0031105
HumanPhenoCompulsive behaviors

EP300 ARID1B CHD7

1.46e-0315883HP:0000722
HumanPhenoAbnormal morphology of female internal genitalia

POLD1 EP300 ARID1B CHD7 DCC

1.49e-0366585HP:0000008
HumanPhenoDigestive system neoplasm

POLD1 EP300 ARID1B DCC

1.58e-0337484HP:0034930
HumanPhenoFunctional abnormality of the inner ear

POLD1 EP300 KIZ ARID1B CHD7 DCC

1.66e-03107786HP:0011389
HumanPhenoSoft tissue sarcoma

POLD1 EP300 DCC

1.69e-0316683HP:0030448
HumanPhenoNeoplasm by histology

POLD1 EP300 ARID1B DCC

1.73e-0338384HP:0011792
HumanPhenoJoint dislocation

EP300 ARID1B CHD7 SEC31A

1.85e-0339084HP:0001373
HumanPhenoAbnormality of the inner ear

POLD1 EP300 KIZ ARID1B CHD7 DCC

1.89e-03110286HP:0000359
HumanPhenoDysplastic corpus callosum

EP300 ARID1B SEC31A DCC

1.94e-0339584HP:0006989
HumanPhenoAbnormality of the upper respiratory tract

POLD1 EP300 ARID1B CHD7 SEC31A DCC

1.98e-03111186HP:0002087
HumanPhenoMale hypogonadism

POLD1 CHD7

2.07e-034582HP:0000026
HumanPhenoAbnormality of skeletal maturation

EP300 ARID1B CHD7 DCC

2.13e-0340584HP:0000927
HumanPhenoBreast hypoplasia

CHD7 DCC

2.16e-034682HP:0003187
HumanPhenoProminent fingertip pads

EP300 ARID1B

2.16e-034682HP:0001212
HumanPhenoAbnormal thyroid morphology

POLD1 ARID1B CHD7

2.24e-0318383HP:0011772
HumanPhenoAbnormally high-pitched voice

POLD1 ARID1B

2.25e-034782HP:0001620
HumanPhenoProminent digit pad

EP300 ARID1B

2.35e-034882HP:0011298
HumanPhenoAbnormality of the female genitalia

POLD1 EP300 ARID1B CHD7 DCC

2.46e-0374185HP:0010460
HumanPhenoAnosmia

CHD7 DCC

2.55e-035082HP:0000458
HumanPhenoAbnormality of mouth size

POLD1 EP300 ARID1B CHD7

2.55e-0342584HP:0011337
HumanPhenoObesity

EP300 KIZ CHD7 DCC

2.55e-0342584HP:0001513
HumanPhenoSelf-mutilation

EP300 CHD7

2.65e-035182HP:0000742
HumanPhenoHyposmia

CHD7 DCC

2.75e-035282HP:0004409
HumanPhenoGastrointestinal ulcer

EP300 ARID1B

2.75e-035282HP:0034274
HumanPhenoAplasia/Hypoplasia of the earlobes

EP300 CHD7

2.86e-035382HP:0009906
HumanPhenoAbnormal hypothalamus physiology

CHD7 DCC

2.86e-035382HP:0012285
HumanPhenoHypogonadism

POLD1 KIZ CHD7 DCC

2.88e-0343984HP:0000135
HumanPhenoAplasia/Hypoplasia of the corpus callosum

EP300 ARID1B PCLO SEC31A DCC

2.97e-0377285HP:0007370
HumanPhenoAbnormal palate morphology

EP300 ARID1B CHD7 PCLO SEC31A DCC

3.06e-03120286HP:0000174
HumanPhenoCryptorchidism

POLD1 EP300 ARID1B CHD7 DCC

3.11e-0378085HP:0000028
HumanPhenoAbnormal cardiac ventricle morphology

POLD1 EP300 ARID1B CHD7 SEC31A

3.11e-0378085HP:0001713
MousePhenoabnormal trabecula carnea morphology

NCOA6 EP300 XIRP1

8.88e-0578163MP:0004067
MousePhenothin myocardium

NCOA6 EP300 CHD7

1.15e-0485163MP:0002652
MousePhenoabsent olfactory bulb

NCOA6 CHD7

1.65e-0417162MP:0003451
MousePhenoabnormal epicardium morphology

NCOA6 EP300

1.65e-0417162MP:0003057
MousePhenodecreased fetal cardiomyocyte proliferation

NCOA6 CHD7

1.86e-0418162MP:0011395
MousePhenoincreased intestinal adenocarcinoma incidence

POLD1 DCC

2.80e-0422162MP:0002957
MousePhenoabnormal ventricle myocardium morphology

NCOA6 EP300 XIRP1

2.88e-04116163MP:0010499
MousePhenoincreased intestinal adenoma incidence

POLD1 DCC

3.63e-0425162MP:0002404
MousePhenoabnormal hypothalamus physiology

ARID1B CHD7

3.93e-0426162MP:0005645
MousePhenoabnormal corpus callosum morphology

ARID1B CHD7 DCC

3.94e-04129163MP:0000780
MousePhenoabnormal dorsal telencephalic commissure morphology

ARID1B CHD7 DCC

4.21e-04132163MP:0008219
MousePhenoabnormal muscle physiology

NCOA6 POLD1 EP300 XIRP1 ARID1B CHD7

4.39e-04954166MP:0002106
MousePhenoabnormal myocardial trabeculae morphology

NCOA6 EP300 XIRP1

5.43e-04144163MP:0002189
MousePhenoabnormal olfactory lobe morphology

POU3F1 NCOA6 CHD7

6.00e-04149163MP:0009944
MousePhenolethality, complete penetrance

ARID1B CHD7

6.35e-0433162MP:0011400
MousePhenodilated third ventricle

NCOA6 CHD7

6.74e-0434162MP:0000827
MousePhenoabnormal brain commissure morphology

ARID1B CHD7 DCC

7.52e-04161163MP:0002199
MousePhenorespiratory failure

PBX3 POU3F1 EP300

8.08e-04165163MP:0001953
MousePhenoembryonic lethality during organogenesis, complete penetrance

BCL9L NCOA6 POLD1 EP300 CHD7

8.54e-04700165MP:0011098
MousePhenodecreased respiration

PBX3 POU3F1 EP300

8.81e-04170163MP:0014274
MousePhenoabnormal myocardium layer morphology

NCOA6 EP300 XIRP1 CHD7

1.04e-03414164MP:0005329
MousePhenoperinatal lethality

PBX3 POU3F1 NCOA6 EP300 ARID1B DCC

1.09e-031130166MP:0002081
MousePhenoabnormal heart layer morphology

NCOA6 EP300 XIRP1 CHD7

1.12e-03422164MP:0010545
MousePhenoincreased megakaryocyte cell number

EP300 DCC

1.18e-0345162MP:0008254
MousePhenoabnormal nervous system tract morphology

ARID1B CHD7 DCC

1.20e-03189163MP:0000778
MousePhenothin myocardium compact layer

NCOA6 EP300

1.23e-0346162MP:0004057
MousePhenoabnormal fetal cardiomyocyte proliferation

NCOA6 CHD7

1.34e-0348162MP:0003567
MousePhenoabnormal brain white matter morphology

ARID1B CHD7 DCC

1.53e-03206163MP:0008026
MousePhenoabnormal trophoblast layer morphology

BCL9L NCOA6 POLD1

1.64e-03211163MP:0005031
MousePhenoabnormal telencephalon morphology

POU3F1 NCOA6 ARID1B CHD7 DCC

1.67e-03812165MP:0000787
MousePhenoabnormal fetal cardiomyocyte physiology

NCOA6 CHD7

1.76e-0355162MP:0011390
MousePhenoabnormal cardiac muscle tissue morphology

NCOA6 EP300 XIRP1 CHD7

1.93e-03489164MP:0010630
MousePhenodecreased erythroid progenitor cell number

NCOA6 DCC

1.96e-0358162MP:0008973
MousePhenoincreased gastrointestinal tumor incidence

POLD1 DCC

1.96e-0358162MP:0010279
MousePhenolethality during fetal growth through weaning, complete penetrance

PBX3 POU3F1 NCOA6 EP300 ARID1B DCC

1.99e-031269166MP:0011111
MousePhenocyanosis

PBX3 POU3F1 EP300

2.00e-03226163MP:0001575
MousePhenoabnormal embryonic growth/weight/body size

BCL9L NCOA6 POLD1 EP300 CHD7 BCL9

2.21e-031295166MP:0002088
MousePhenoabnormal fibroblast apoptosis

NCOA6 DCC

2.23e-0362162MP:0013500
MousePhenoembryonic lethality during organogenesis

BCL9L NCOA6 POLD1 EP300 CHD7

2.33e-03876165MP:0006207
MousePhenoincreased alimentary system tumor incidence

POLD1 DCC

2.45e-0365162MP:0010292
MousePhenoabnormal respiratory system physiology

PBX3 POU3F1 EP300 CHD7 DCC

2.59e-03897165MP:0002133
MousePhenoabnormal myocardium compact layer morphology

NCOA6 EP300

2.60e-0367162MP:0004056
MousePhenoabnormal oxygen level

PBX3 POU3F1 EP300

2.85e-03256163MP:0001574
MousePhenoventricle myocardium hypoplasia

NCOA6 EP300

2.91e-0371162MP:0010502
MousePhenoembryonic lethality during organogenesis, incomplete penetrance

NCOA6 EP300 CHD7

3.24e-03268163MP:0011108
MousePhenoabnormal fibroblast physiology

NCOA6 EP300 DCC

3.35e-03271163MP:0020414
MousePhenoabnormal embryo size

BCL9L NCOA6 POLD1 EP300 BCL9

3.42e-03956165MP:0001697
MousePhenoabnormal third ventricle morphology

NCOA6 CHD7

3.51e-0378162MP:0000826
MousePhenoabnormal palatal shelf fusion at midline

NCOA6 CHD7

3.68e-0380162MP:0009887
MousePhenoabnormal brain ventricle morphology

NCOA6 ARID1B CHD7

3.89e-03286163MP:0000822
MousePhenoabnormal somatic nervous system physiology

PBX3 CHD7

3.96e-0383162MP:0005423
MousePhenoabnormal respiration

PBX3 POU3F1 EP300 DCC

4.00e-03598164MP:0001943
MousePhenoabnormal gas homeostasis

PBX3 POU3F1 EP300 CHD7

4.05e-03600164MP:0003948
MousePhenomyocardium hypoplasia

NCOA6 EP300

4.24e-0386162MP:0010500
MousePhenoabnormal megakaryocyte morphology

EP300 DCC

4.24e-0386162MP:0002417
MousePhenoabnormal prenatal growth/weight/body size

BCL9L NCOA6 POLD1 EP300 CHD7 BCL9

4.57e-031493166MP:0004196
DomainBCL9_beta-catenin-bd_dom

BCL9L BCL9

1.20e-062212IPR024670
DomainBCL9

BCL9L BCL9

1.20e-062212PF11502
DomainBcl-9

BCL9L BCL9

1.20e-062212IPR015668
DomainZnf_FYVE_PHD

PCLO PYGO1

1.17e-02147212IPR011011
DomainHomeobox_CS

PBX3 POU3F1

1.83e-02186212IPR017970
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L EP300 PYGO1 BCL9

3.46e-0826194MM14793
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

BCL9L EP300 PYGO1 BCL9

5.85e-0691194M27101
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

BCL9L PYGO1 BCL9

2.31e-0542193M27272
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

BCL9L EP300 PYGO1 BCL9

5.16e-05158194MM14791
PathwayWNT_SIGNALING

EP300 PYGO1 BCL9

2.19e-0489193M5493
PathwayREACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT

BCL9L EP300 PYGO1 BCL9

2.32e-04233194M27099
PathwayREACTOME_SIGNALING_BY_WNT

BCL9L EP300 PYGO1 BCL9

2.56e-04239194MM14756
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA6 EP300

2.60e-0418192M26942
PathwayWP_WNTBETACATENIN_SIGNALING_IN_LEUKEMIA

PYGO1 BCL9

5.49e-0426192M39407
PathwayWP_KLEEFSTRA_SYNDROME

NCOA6 ARID1B

6.84e-0429192M48076
PathwayWP_1Q211_COPY_NUMBER_VARIATION_SYNDROME

PYGO1 BCL9

6.84e-0429192M39890
PathwayREACTOME_SIGNALING_BY_WNT

BCL9L EP300 PYGO1 BCL9

8.65e-04330194M7847
PathwayREACTOME_RUNX1_INTERACTS_WITH_CO_FACTORS_WHOSE_PRECISE_EFFECT_ON_RUNX1_TARGETS_IS_NOT_KNOWN

EP300 ARID1B

1.11e-0337192M27797
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

NCOA6 EP300 ARID1B CHD7 BCL9

1.75e-098322528794006
Pubmed

Bcl9 and Pygo synergise downstream of Apc to effect intestinal neoplasia in FAP mouse models.

BCL9L PYGO1 BCL9

2.19e-09522330760710
Pubmed

TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex.

BCL9L PYGO1 BCL9

2.19e-09522332808927
Pubmed

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling.

BCL9L PYGO1 BCL9

4.39e-09622315574752
Pubmed

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development.

BCL9L PYGO1 BCL9

4.39e-09622325184676
Pubmed

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling.

BCL9L PYGO1 BCL9

7.68e-09722330366904
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

BCL9L WDR33 NCOA6 ARID1B CHD7 BCL9

1.33e-0826822633640491
Pubmed

Interaction network of human early embryonic transcription factors.

BCL9L NCOA6 EP300 ARID1B CHD7 BCL9

6.59e-0835122638297188
Pubmed

A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.

BCL9L PYGO1 BCL9

7.96e-081422328174279
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

BCL9L WDR33 NCOA6 EP300 ARID1B BCL9

3.11e-0745722632344865
Pubmed

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex.

PYGO1 BCL9

3.82e-07222218498752
Pubmed

Bcl9/Bcl9l are critical for Wnt-mediated regulation of stem cell traits in colon epithelium and adenocarcinomas.

BCL9L BCL9

3.82e-07222220682801
Pubmed

Targeting BCL9/BCL9L enhances antigen presentation by promoting conventional type 1 dendritic cell (cDC1) activation and tumor infiltration.

BCL9L BCL9

3.82e-07222238811552
Pubmed

BCL9/BCL9L promotes tumorigenicity through immune-dependent and independent mechanisms in triple negative breast cancer.

BCL9L BCL9

3.82e-07222233767438
Pubmed

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.

BCL9L BCL9

3.82e-07222215371335
Pubmed

Pygopus residues required for its binding to Legless are critical for transcription and development.

PYGO1 BCL9

1.15e-06322214612447
Pubmed

The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote breast cancer growth, invasion, and metastasis.

BCL9L BCL9

1.15e-06322234545187
Pubmed

Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells.

BCL9L BCL9

1.15e-06322233649334
Pubmed

Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor.

BCL9L BCL9

1.15e-06322220637214
Pubmed

Human transcription factor protein interaction networks.

BCL9L WDR33 NCOA6 EP300 ARID1B CHD7 PYGO1 BCL9

1.52e-06142922835140242
Pubmed

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.

PYGO1 BCL9

2.29e-06422211955446
Pubmed

Transcriptional coactivator PRIP, the peroxisome proliferator-activated receptor gamma (PPARgamma)-interacting protein, is required for PPARgamma-mediated adipogenesis.

NCOA6 EP300

2.29e-06422212754253
Pubmed

BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration.

BCL9L BCL9

2.29e-06422219699733
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

NCOA6 EP300 ARID1B CHD7

2.74e-0615722430186101
Pubmed

Crystal structure of a beta-catenin/BCL9/Tcf4 complex.

BCL9L BCL9

3.82e-06522217052462
Pubmed

Interaction of PIMT with transcriptional coactivators CBP, p300, and PBP differential role in transcriptional regulation.

NCOA6 EP300

3.82e-06522211912212
Pubmed

LATS2 suppresses oncogenic Wnt signaling by disrupting β-catenin/BCL9 interaction.

BCL9L BCL9

3.82e-06522224360964
Pubmed

Aristaless Related Homeobox (ARX) Interacts with β-Catenin, BCL9, and P300 to Regulate Canonical Wnt Signaling.

EP300 BCL9

3.82e-06522228103279
Pubmed

The post-translational modifications of proliferating cell nuclear antigen: acetylation, not phosphorylation, plays an important role in the regulation of its function.

POLD1 EP300

3.82e-06522214988403
Pubmed

CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.

POLD1 EP300

3.82e-06522224939902
Pubmed

A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential.

BCL9L BCL9

3.82e-06522219328798
Pubmed

Loss of BCL9/9l suppresses Wnt driven tumourigenesis in models that recapitulate human cancer.

BCL9L BCL9

5.72e-06622230760720
Pubmed

BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.

BCL9L BCL9

5.72e-06622217113272
Pubmed

Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM).

NCOA6 EP300

5.72e-06622211443112
Pubmed

Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity.

PYGO1 BCL9

5.72e-06622221399610
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

BCL9L NCOA6 EP300 PCLO BCL9

5.91e-0642522524999758
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

WDR33 NCOA6 ARID1B TRMT6 SEC31A

9.81e-0647222538943005
Pubmed

Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans.

SEC31A BCL9

1.07e-05822224239381
Pubmed

Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator.

NCOA6 EP300

1.07e-05822210823961
Pubmed

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.

BCL9L BCL9

1.07e-05822228296634
Pubmed

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping.

NCOA6 ARID1B CHD7

1.62e-057822328611094
Pubmed

USP9X-mediated deubiquitination of B-cell CLL/lymphoma 9 potentiates Wnt signaling and promotes breast carcinogenesis.

PYGO1 BCL9

2.09e-051122231073027
Pubmed

Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.

EP300 PYGO1 BCL9

2.49e-059022319515997
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

NCOA6 EP300

2.51e-051222212189208
Pubmed

Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system.

PBX3 DCC

2.51e-051222224009623
Pubmed

FGF signaling through FGFR1 is required for olfactory bulb morphogenesis.

PBX3 POU3F1

3.46e-051422212571102
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA6 EP300 ARID1B CHD7 BCL9

4.16e-0563822531182584
Pubmed

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

NCOA6 EP300

4.56e-051622223870121
Pubmed

The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome.

SEC31A BCL9

4.56e-051622222792322
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

NCOA6 SF3A2 EP300 ARID1B CHD7 BCL9

4.84e-05110322634189442
Pubmed

ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.

NCOA6 EP300 CHD7

4.92e-0511322334474245
Pubmed

Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling.

NCOA6 EP300

5.16e-051722228291835
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

WDR33 NCOA6 SF3A2 ARID1B

5.78e-0534122432971831
Pubmed

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.

ARID1B DCC

5.81e-051822220602751
Pubmed

Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.

PBX3 POU3F1 DCC

6.80e-0512622316284245
Pubmed

Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum.

POU3F1 DCC

7.21e-052022216309667
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

NCOA6 EP300

7.21e-052022211877444
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOA6 EP300

7.96e-052122219596656
Pubmed

Sox2 modulates the function of two distinct cell lineages in mouse skin.

PCLO DCC

7.96e-052122223948231
Pubmed

The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.

PBX3 DCC

8.76e-052222222748019
Pubmed

Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.

NDUFA3 DCC

8.76e-052222227407143
Pubmed

The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex.

POLD1 EP300 KIZ

1.01e-0414422330585266
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

ARID1B CHD7 PCLO TRMT6

1.03e-0439622426687479
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

EP300 ARID1B CHD7 PCLO

1.05e-0439822435016035
Pubmed

Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs.

PBX3 POU3F1

1.14e-042522229379870
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

WDR33 EP300 BCL9

1.19e-0415222338360978
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

BCL9L WDR33 BCL9

1.95e-0418022335198878
Pubmed

Lynch Syndrome

EP300 DCC

1.99e-043322220301390
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

BCL9L EP300

2.12e-043422230894540
Pubmed

Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study.

POU3F1 DCC

2.24e-043522223192594
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

EP300 ARID1B

2.94e-044022234585037
Pubmed

Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.

WDR33 SF3A2 BCL9

3.52e-0422022324550385
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

WDR33 NCOA6 EP300 ARID1B

3.58e-0454922438280479
Pubmed

Congenital Diaphragmatic Hernia Overview

ARID1B CHD7

3.89e-044622220301533
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

WDR33 SF3A2 POLD1 CHD7

4.47e-0458222420467437
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

PBX3 SF3A2 POLD1 CHD7

4.50e-0458322429844126
Pubmed

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor.

ARID1B SEC31A

4.59e-045022227716508
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

WDR33 SF3A2 ARID1B CHD7 SEC31A

4.89e-04108222538697112
Pubmed

The SWI/SNF chromatin remodeling factor DPF3 regulates metastasis of ccRCC by modulating TGF-β signaling.

EP300 ARID1B

5.56e-045522235945219
Pubmed

Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior.

EP300 ARID1B

5.76e-045622229184203
Pubmed

Parallel Pbx-Dependent Pathways Govern the Coalescence and Fate of Motor Columns.

PBX3 POU3F1

6.18e-045822227568519
InteractionSP7 interactions

BCL9L WDR33 NCOA6 EP300 ARID1B CHD7 PYGO1 BCL9

6.51e-10304228int:SP7
InteractionPAX9 interactions

BCL9L NCOA6 EP300 ARID1B CHD7 BCL9

4.40e-09130226int:PAX9
InteractionEGR2 interactions

BCL9L NCOA6 EP300 ARID1B CHD7 BCL9

2.28e-08171226int:EGR2
InteractionSOX9 interactions

NCOA6 EP300 ARID1B CHD7 BCL9

5.74e-0897225int:SOX9
InteractionTBR1 interactions

BCL9L EP300 ARID1B CHD7 BCL9

1.24e-07113225int:TBR1
InteractionTBXT interactions

NCOA6 EP300 ARID1B CHD7 BCL9

1.41e-07116225int:TBXT
InteractionAR interactions

BCL9L WDR33 NCOA6 POLD1 EP300 ARID1B CHD7 DCC BCL9

4.55e-07992229int:AR
InteractionSSBP4 interactions

BCL9L EP300 PYGO1 BCL9

4.66e-0759224int:SSBP4
InteractionTLX3 interactions

BCL9L NCOA6 EP300 ARID1B CHD7 BCL9

5.29e-07291226int:TLX3
InteractionLHX4 interactions

BCL9L ARID1B CHD7 PYGO1 BCL9

8.39e-07166225int:LHX4
InteractionTLX1 interactions

EP300 ARID1B CHD7 PYGO1 BCL9

1.09e-06175225int:TLX1
InteractionLHX2 interactions

BCL9L ARID1B CHD7 PYGO1 BCL9

1.36e-06183225int:LHX2
InteractionGATA2 interactions

NCOA6 EP300 ARID1B CHD7 BCL9

2.05e-06199225int:GATA2
InteractionGSC interactions

BCL9L EP300 ARID1B BCL9

2.23e-0687224int:GSC
InteractionFEV interactions

NCOA6 EP300 ARID1B CHD7 BCL9

2.26e-06203225int:FEV
InteractionSOX10 interactions

EP300 ARID1B CHD7 BCL9

2.79e-0692224int:SOX10
InteractionSOX17 interactions

NCOA6 ARID1B CHD7 BCL9

3.18e-0695224int:SOX17
InteractionERG interactions

NCOA6 EP300 ARID1B CHD7 BCL9

3.58e-06223225int:ERG
InteractionPYGO1 interactions

BCL9L PYGO1 BCL9

3.63e-0628223int:PYGO1
InteractionNUP35 interactions

BCL9L WDR33 NCOA6 EP300 ARID1B BCL9

4.69e-06424226int:NUP35
InteractionSSBP2 interactions

BCL9L EP300 PYGO1 BCL9

4.73e-06105224int:SSBP2
InteractionPAX8 interactions

EP300 ARID1B CHD7 BCL9

5.91e-06111224int:PAX8
InteractionCRX interactions

BCL9L EP300 ARID1B CHD7 BCL9

6.76e-06254225int:CRX
InteractionLDB1 interactions

BCL9L EP300 PYGO1 BCL9

6.80e-06115224int:LDB1
InteractionPAX7 interactions

EP300 ARID1B CHD7 BCL9

9.17e-06124224int:PAX7
InteractionISL1 interactions

BCL9L PYGO1 BCL9

1.17e-0541223int:ISL1
InteractionISL2 interactions

BCL9L PYGO1 BCL9

1.17e-0541223int:ISL2
InteractionBCL9L interactions

BCL9L PYGO1 BCL9

1.89e-0548223int:BCL9L
InteractionORC6 interactions

BCL9L PYGO1 BCL9

2.01e-0549223int:ORC6
InteractionPAX6 interactions

NCOA6 EP300 ARID1B CHD7 BCL9

3.92e-05366225int:PAX6
InteractionALG13 interactions

WDR33 EP300 ARID1B BCL9

4.23e-05183224int:ALG13
InteractionLHX3 interactions

ARID1B CHD7 DCC BCL9

4.42e-05185224int:LHX3
InteractionGATA3 interactions

EP300 ARID1B CHD7 BCL9

4.61e-05187224int:GATA3
InteractionHNF1B interactions

EP300 ARID1B CHD7 BCL9

4.90e-05190224int:HNF1B
InteractionGCM1 interactions

EP300 ARID1B BCL9

5.40e-0568223int:GCM1
InteractionKLF5 interactions

NCOA6 EP300 ARID1B BCL9

5.42e-05195224int:KLF5
InteractionETV4 interactions

EP300 ARID1B BCL9

5.65e-0569223int:ETV4
InteractionASCL2 interactions

NCOA6 EP300

8.81e-0513222int:ASCL2
InteractionSOX7 interactions

EP300 ARID1B CHD7

9.46e-0582223int:SOX7
InteractionPAX2 interactions

ARID1B CHD7 BCL9

1.05e-0485223int:PAX2
InteractionIRF4 interactions

EP300 ARID1B CHD7

1.05e-0485223int:IRF4
InteractionBCL9 interactions

BCL9L PYGO1 BCL9

1.09e-0486223int:BCL9
InteractionSNW1 interactions

WDR33 SF3A2 POLD1 EP300 CHD7 TRMT6

1.14e-04747226int:SNW1
InteractionPCAT1 interactions

EP300 PCLO

1.18e-0415222int:PCAT1
InteractionFOXI1 interactions

EP300 ARID1B BCL9

1.33e-0492223int:FOXI1
InteractionASF1A interactions

NCOA6 EP300 ARID1B CHD7

1.40e-04249224int:ASF1A
InteractionNANOG interactions

WDR33 EP300 ARID1B CHD7 TRMT6

1.43e-04481225int:NANOG
InteractionLHX1 interactions

ARID1B CHD7 BCL9

1.86e-04103223int:LHX1
InteractionHNF4A interactions

NCOA6 EP300 ARID1B CHD7

2.04e-04275224int:HNF4A
InteractionPOU3F2 interactions

POU3F1 EP300

2.14e-0420222int:POU3F2
InteractionEN1 interactions

PBX3 EP300 CHD7

2.26e-04110223int:EN1
InteractionRBBP5 interactions

WDR33 NCOA6 EP300 CHD7

2.41e-04287224int:RBBP5
InteractionTERF2IP interactions

WDR33 NCOA6 POLD1 CHD7 TRMT6

2.71e-04552225int:TERF2IP
InteractionPPARD interactions

POLD1 EP300 TRMT6

2.71e-04117223int:PPARD
InteractionHOXD10 interactions

PBX3 EP300

2.84e-0423222int:HOXD10
InteractionSSBP3 interactions

BCL9L PYGO1 BCL9

2.85e-04119223int:SSBP3
InteractionFOS interactions

NCOA6 EP300 ARID1B BCL9

3.31e-04312224int:FOS
InteractionPOU5F1 interactions

WDR33 SF3A2 ARID1B CHD7 TRMT6

3.51e-04584225int:POU5F1
InteractionSLC30A5 interactions

CYB5D2 EP300 SEC31A

3.95e-04133223int:SLC30A5
InteractionSOX15 interactions

EP300 ARID1B BCL9

4.68e-04141223int:SOX15
InteractionTLX2 interactions

ARID1B CHD7 BCL9

4.78e-04142223int:TLX2
InteractionHOXD4 interactions

PBX3 EP300

4.86e-0430222int:HOXD4
InteractionSNRNP40 interactions

BCL9L SF3A2 POLD1 ARID1B BCL9

5.23e-04637225int:SNRNP40
InteractionELF5 interactions

EP300 ARID1B CHD7

5.29e-04147223int:ELF5
InteractionNR1H4 interactions

NCOA6 EP300

5.53e-0432222int:NR1H4
InteractionARID2 interactions

POLD1 ARID1B CHD7

5.94e-04153223int:ARID2
InteractionLMO4 interactions

BCL9L PYGO1 BCL9

6.65e-04159223int:LMO4
InteractionTLE3 interactions

BCL9L EP300 ARID1B BCL9

6.68e-04376224int:TLE3
InteractionKLF4 interactions

EP300 ARID1B BCL9

6.77e-04160223int:KLF4
InteractionE2F5 interactions

EP300 ARID1B

7.01e-0436222int:E2F5
InteractionHOXB2 interactions

EP300 ARID1B

7.01e-0436222int:HOXB2
InteractionTBC1D2 interactions

POLD1 DCC

7.40e-0437222int:TBC1D2
InteractionGATA1 interactions

EP300 ARID1B BCL9

8.21e-04171223int:GATA1
InteractionTEAD1 interactions

EP300 ARID1B CHD7

8.92e-04176223int:TEAD1
InteractionSUPT5H interactions

WDR33 EP300 ARID1B CHD7

9.07e-04408224int:SUPT5H
InteractionFKBP5 interactions

POLD1 CHD7 TRMT6 NDUFA3

9.57e-04414224int:FKBP5
InteractionMDC1 interactions

WDR33 POLD1 EP300 ARID1B

9.57e-04414224int:MDC1
InteractionHEMGN interactions

EP300 DCC

1.05e-0344222int:HEMGN
InteractionTHRB interactions

NCOA6 EP300 CHD7

1.05e-03186223int:THRB
InteractionTFIP11 interactions

PBX3 CCDC187 SF3A2 KIZ

1.07e-03427224int:TFIP11
InteractionNFIA interactions

EP300 ARID1B BCL9

1.08e-03188223int:NFIA
InteractionRORC interactions

NCOA6 EP300

1.09e-0345222int:RORC
InteractionMYOD1 interactions

EP300 ARID1B BCL9

1.18e-03194223int:MYOD1
InteractionPYGO2 interactions

BCL9L BCL9

1.24e-0348222int:PYGO2
InteractionNR1I2 interactions

NCOA6 EP300

1.24e-0348222int:NR1I2
InteractionPRPS1 interactions

POLD1 EP300 TRMT6

1.27e-03199223int:PRPS1
InteractionE2F1 interactions

NCOA6 EP300 ARID1B

1.29e-03200223int:E2F1
InteractionUSP43 interactions

POLD1 TRMT6

1.46e-0352222int:USP43
InteractionHES6 interactions

POLD1 EP300

1.46e-0352222int:HES6
InteractionLHX8 interactions

PYGO1 BCL9

1.52e-0353222int:LHX8
InteractionCAPN1 interactions

WDR33 POLD1 EP300

1.59e-03215223int:CAPN1
InteractionLDB2 interactions

EP300 PYGO1

1.69e-0356222int:LDB2
InteractionTPRX2 interactions

NCOA6 ARID1B

1.69e-0356222int:TPRX2
InteractionDUS3L interactions

EP300 TRMT6

1.69e-0356222int:DUS3L
InteractionCEBPA interactions

NCOA6 SF3A2 EP300 ARID1B CHD7 BCL9

1.74e-031245226int:CEBPA
InteractionNOP14 interactions

POLD1 EP300 SEC31A

1.74e-03222223int:NOP14
InteractionSRSF9 interactions

SF3A2 POLD1 EP300

1.78e-03224223int:SRSF9
InteractionLHX6 interactions

BCL9L BCL9

1.81e-0358222int:LHX6
InteractionNR1H3 interactions

NCOA6 EP300

1.81e-0358222int:NR1H3
GeneFamilyWD repeat domain containing

WDR33 SEC31A

1.47e-02262132362
CoexpressionGSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_DN

BCL9L WDR33 SF3A2 BCL9

2.16e-05200224M4352
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

POU3F1 NCOA6 KIZ CHD7 PCLO TRMT6 DCC

4.29e-05989227Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

BCL9L CYB5D2 POU3F1 NCOA6

1.05e-06159224b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

KIZ CHD7 NDUFA3 SEC31A

2.55e-06199224a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PBX3 KIZ DCC

9.94e-051852239f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellBrain_organoid-organoid_Kanton_Nature|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.

PBX3 CHD7 DCC

9.94e-05185223857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-Immature_INs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

PBX3 ARID1B CHD7

1.08e-04190223842760bfe0a52e67bad800efa7d99448a4a23ebb
ToppCellfacs-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POU3F1 SF3A2 NDUFA3

1.11e-041922231f81b356520b5506051383d37fae204d59795336
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron|10w / Sample Type, Dataset, Time_group, and Cell type.

PBX3 CHD7 DCC

1.25e-04200223332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Mesoderm|5w / Sample Type, Dataset, Time_group, and Cell type.

FAM171A2 BCL9L EP300

1.25e-042002230927061536a664b4f7feb9e5b0a8c11ca0d5955c
Diseaseattention deficit hyperactivity disorder, bipolar disorder, autism spectrum disorder, schizophrenia, major depressive disorder

KIZ PCLO DCC

7.32e-0651223EFO_0003756, EFO_0003888, MONDO_0002009, MONDO_0004985, MONDO_0005090
Diseaseirritable bowel syndrome

EP300 PCLO DCC

1.24e-04131223EFO_0000555
Diseaseresponse to mTOR inhibitor

PBX3 DCC

1.58e-0425222EFO_0005417
DiseaseKallmann Syndrome

CHD7 DCC

1.71e-0426222C0162809
Diseasetaste liking measurement

PBX3 EP300 ARID1B DCC

1.79e-04388224EFO_0010155
DiseaseColorectal cancer

EP300 DCC

1.84e-0427222cv:C0346629
DiseaseCOLORECTAL CANCER

EP300 DCC

1.84e-0427222114500
DiseaseNeoplasm of the large intestine

EP300 DCC

1.84e-0427222cv:C0009404
DiseaseBreast adenocarcinoma

EP300 ARID1B

4.28e-0441222C0858252
DiseaseNeoplasm of uncertain or unknown behavior of breast

EP300 ARID1B

4.28e-0441222C0496956
Diseaseobsessive-compulsive disorder, attention deficit hyperactivity disorder, Tourette syndrome, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia, anorexia nervosa

KIZ PCLO DCC

4.30e-04200223EFO_0003756, EFO_0003761, EFO_0003888, EFO_0004242, EFO_0004895, MONDO_0004985, MONDO_0005090, MONDO_0005351
Diseasepneumonia

PBX3 BCL9L

5.62e-0447222EFO_0003106
DiseaseDiffuse Large B-Cell Lymphoma

EP300 SEC31A

7.69e-0455222C0079744
DiseaseEndometrial Neoplasms

POLD1 EP300

8.55e-0458222C0014170
DiseaseMalignant neoplasm of breast

NCOA6 EP300 XIRP1 ARID1B NDUFA3

9.94e-041074225C0006142
DiseaseColorectal Neoplasms

POLD1 EP300 DCC

1.10e-03277223C0009404
Diseaseaggressive behaviour measurement, ADHD symptom measurement

NCOA6 DCC

1.17e-0368222EFO_0007826, EFO_0007860
DiseaseEndometrial Carcinoma

POLD1 EP300

1.31e-0372222C0476089
DiseaseSelf-injurious behavior

ARID1B DCC

1.54e-0378222HP_0100716
DiseaseColorectal Carcinoma

CYB5D2 POLD1 EP300 DCC

1.65e-03702224C0009402
DiseaseAdenocarcinoma of large intestine

EP300 DCC

2.32e-0396222C1319315
Diseasegastroesophageal reflux disease

PBX3 DCC

2.56e-03101222EFO_0003948
Diseaseneurotic disorder

PCLO DCC

2.56e-03101222EFO_0004257
Diseaseattention deficit hyperactivity disorder, autism spectrum disorder, intelligence

KIZ ARID1B DCC

3.10e-03398223EFO_0003756, EFO_0003888, EFO_0004337
Diseasecolorectal cancer (is_implicated_in)

EP300 DCC

3.65e-03121222DOID:9256 (is_implicated_in)
Diseasemood instability measurement

EP300 DCC

4.07e-03128222EFO_0008475

Protein segments in the cluster

PeptideGeneStartEntry
PGLQPPTMPGQQGVH

EP300

2111

Q09472
NHAETLDPPGMGGPQ

CCDC187

751

A0A096LP49
AGGGAPQPGPDMEQP

ARID1B

226

Q8NFD5
PQPGPDMEQPQHGGA

ARID1B

231

Q8NFD5
GPPAQGHPQHMQQMG

CHD7

176

Q9P2D1
VQGGMALPPPPHGHE

PBX3

21

P40426
NEPPIGQMHPPHGSV

DCC

1076

P43146
QPGPHSQSGPGAPMK

PCLO

951

Q9Y6V0
MSPSPGASGGHQPQP

POU3F1

141

Q03052
SPEPQPNPGGKMEGE

KIZ

391

Q2M2Z5
PQRPQMPGHSGPGGE

FAM171A2

581

A8MVW0
PGPSPHMAQQHGDPA

NCOA6

791

Q14686
NAVGPNIPPHGVPMG

BCL9

1096

O00512
HEVPGHPPGGDMGQQ

BCL9L

486

Q86UU0
PAPPGFGPEHMGDLQ

POLD1

151

P28340
NQPHPFPQNPLGMGF

PYGO1

126

Q9Y3Y4
PSGQMPDNPPHRNRG

CYB5D2

226

Q8WUJ1
PAPGMHPQAPGVHPQ

SF3A2

396

Q15428
GNMPDVPSHPQDPQG

NDUFA3

61

O95167
MEGSGEQPGPQPQHP

TRMT6

1

Q9UJA5
PPQGLPRPQDMHGPQ

WDR33

661

Q9C0J8
ENPPPPGFIMHGNVN

SEC31A

836

O94979
GPGPSGEQPMEGSHQ

XIRP1

1441

Q702N8