Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	nuclear protein-containing complex	ANAPC10 WDR36 POLR2B DDX42 NR5A2 NVL RAD9B U2AF2 MAFB BRCC3 SMG5 LSM2 RFX5 NR1H4 PHC2 MAF	6.55e-05	1377	81	16	GO:0140513
Domain	Maf_N	NRL MAFA MAFB MAF	3.28e-10	4	81	4	PF08383
Domain	Maf_TF_N	NRL MAFA MAFB MAF	3.28e-10	4	81	4	IPR013592
Domain	Transciption_factor_Maf_fam	NRL MAFA MAFB MAF	1.14e-08	7	81	4	IPR024874
Domain	bZIP_Maf	NRL MAFA MAFB MAF	2.28e-07	13	81	4	IPR004826
Domain	bZIP_Maf	NRL MAFA MAFB MAF	2.28e-07	13	81	4	PF03131
Domain	-	NRL MAFA MAFB MAF	5.74e-07	16	81	4	1.10.880.10
Domain	TF_DNA-bd	NRL MAFA MAFB MAF	1.94e-05	37	81	4	IPR008917
Domain	BRLZ	NRL MAFA MAFB MAF	7.59e-05	52	81	4	SM00338
Domain	BZIP	NRL MAFA MAFB MAF	8.18e-05	53	81	4	PS50217
Domain	BZIP_BASIC	NRL MAFA MAFB MAF	8.18e-05	53	81	4	PS00036
Domain	bZIP	NRL MAFA MAFB MAF	8.80e-05	54	81	4	IPR004827
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1	1.84e-04	5	81	2	IPR016346
Domain	WD40_repeat_dom	ZNF106 WDR36 UBR4 DTL GNB4 GNB1 DMXL1	3.05e-04	297	81	7	IPR017986
Domain	-	ZNF106 WDR36 SEMA6D DTL GNB4 GNB1 DMXL1	6.04e-04	333	81	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	ZNF106 WDR36 SEMA6D DTL GNB4 GNB1 DMXL1	6.26e-04	335	81	7	IPR015943
Domain	SAM_DOMAIN	SGMS1 SAMD15 ARAP1 PHC2	7.75e-04	95	81	4	PS50105
Domain	Gprotein_B	GNB4 GNB1	8.17e-04	10	81	2	IPR001632
Domain	SAM	SGMS1 SAMD15 ARAP1 PHC2	8.38e-04	97	81	4	IPR001660
Domain	WD40	ZNF106 WDR36 DTL GNB4 GNB1 DMXL1	9.14e-04	259	81	6	PF00400
Domain	WD40	ZNF106 WDR36 DTL GNB4 GNB1 DMXL1	1.09e-03	268	81	6	SM00320
Domain	-	SGMS1 SAMD15 ARAP1 PHC2	1.17e-03	106	81	4	1.10.150.50
Domain	WD40_repeat	ZNF106 WDR36 DTL GNB4 GNB1 DMXL1	1.18e-03	272	81	6	IPR001680
Domain	WD_REPEATS_1	ZNF106 WDR36 DTL GNB4 GNB1 DMXL1	1.31e-03	278	81	6	PS00678
Domain	WD_REPEATS_2	ZNF106 WDR36 DTL GNB4 GNB1 DMXL1	1.34e-03	279	81	6	PS50082
Domain	WD_REPEATS_REGION	ZNF106 WDR36 DTL GNB4 GNB1 DMXL1	1.34e-03	279	81	6	PS50294
Domain	VitD_rcpt	NR5A2 NR1H4	1.63e-03	14	81	2	IPR000324
Domain	SAM/pointed	SGMS1 SAMD15 ARAP1 PHC2	1.68e-03	117	81	4	IPR013761
Domain	SAM_1	SGMS1 ARAP1 PHC2	3.22e-03	68	81	3	PF00536
Domain	WD40_repeat_CS	WDR36 DTL GNB4 GNB1	5.64e-03	164	81	4	IPR019775
Pubmed	Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis.	MAFA MAFB MAF	6.69e-08	4	90	3	28933784
Pubmed	Members of the large Maf transcription family regulate insulin gene transcription in islet beta cells.	MAFA MAFB MAF	1.67e-07	5	90	3	12917329
Pubmed	MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice.	NRL MAFA MAFB MAF	2.43e-07	21	90	4	29324782
Pubmed	Role of large MAF transcription factors in the mouse endocrine pancreas.	MAFA MAFB MAF	3.33e-07	6	90	3	25912440
Pubmed	Neither MafA/L-Maf nor MafB is essential for lens development in mice.	MAFA MAFB MAF	5.82e-07	7	90	3	19624757
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	ESYT2 ANAPC10 GTF3C1 RADX POLR2B ASPM U2AF2 DHX57 BRCC3 DNAJC7 LACTB	1.31e-06	670	90	11	22990118
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MRPS31 ESYT2 WDR36 WIZ EXD2 POLR2B UBR4 DTL U2AF2 DHX57 GNB4 RMND1 DBT GNB1 DNAJC7 LACTB	1.34e-06	1496	90	16	32877691
Pubmed	Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse.	MAFA MAFB MAF	1.39e-06	9	90	3	22120711
Pubmed	Regulation of lens fiber cell differentiation by transcription factor c-Maf.	NRL MAFB MAF	1.98e-06	10	90	3	10383433
Pubmed	A switch from MafB to MafA expression accompanies differentiation to pancreatic beta-cells.	MAFA MAFB MAF	3.62e-06	12	90	3	16580660
Pubmed	Two distinct origins for Leydig cell progenitors in the fetal testis.	MAFA MAFB MAF	5.97e-06	14	90	3	21255566
Pubmed	Epidermal differentiation gene regulatory networks controlled by MAF and MAFB.	MAFB MAF	6.62e-06	2	90	2	27097296
Pubmed	Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter.	NR5A2 NR1H4	6.62e-06	2	90	2	12456679
Pubmed	Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination.	MAFA MAFB	6.62e-06	2	90	2	36952339
Pubmed	Developmental contribution of c-maf in the kidney: distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of c-maf knockout mice kidney and liver.	MAFB MAF	6.62e-06	2	90	2	15249232
Pubmed	Genome-wide analysis of hepatic LRH-1 reveals a promoter binding preference and suggests a role in regulating genes of lipid metabolism in concert with FXR.	NR5A2 NR1H4	6.62e-06	2	90	2	22296850
Pubmed	MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages.	MAFB MAF	6.62e-06	2	90	2	19892988
Pubmed	Generation and characterization of MafA-Kusabira Orange mice.	MAFA MAFB	6.62e-06	2	90	2	25273397
Pubmed	MAFB and MAF Transcription Factors as Macrophage Checkpoints for COVID-19 Severity.	MAFB MAF	6.62e-06	2	90	2	33312178
Pubmed	An Inducible Diabetes Mellitus Murine Model Based on MafB Conditional Knockout under MafA-Deficient Condition.	MAFA MAFB	6.62e-06	2	90	2	32764399
Pubmed	Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1.	NR5A2 NR1H4	6.62e-06	2	90	2	20483916
Pubmed	c-Maf and MafB transcription factors are differentially expressed in Huxley's and Henle's layers of the inner root sheath of the hair follicle and regulate cuticle formation.	MAFB MAF	6.62e-06	2	90	2	20060689
Pubmed	Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA.	MAFA MAF	6.62e-06	2	90	2	12011435
Pubmed	Inhibition of Small Maf Function in Pancreatic β-Cells Improves Glucose Tolerance Through the Enhancement of Insulin Gene Transcription and Insulin Secretion.	MAFA MAF	6.62e-06	2	90	2	25763640
Pubmed	MafA is a dedicated activator of the insulin gene in vivo.	MAFA MAFB	6.62e-06	2	90	2	18515495
Pubmed	MafB Maintains β-Cell Identity under MafA-Deficient Conditions.	MAFA MAFB	6.62e-06	2	90	2	35862726
Pubmed	Differential expression patterns of MafB and c-Maf in macrophages in vivo and in vitro.	MAFB MAF	6.62e-06	2	90	2	26996125
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	ATP6V0A1 ANAPC10 GTF3C1 POLR2B ASPM MKLN1 NVL DNAJC7 LACTB	1.02e-05	533	90	9	25544563
Pubmed	MafB is required for islet beta cell maturation.	MAFA MAFB MAF	1.33e-05	18	90	3	17360442
Pubmed	MafA is critical for maintenance of the mature beta cell phenotype in mice.	MAFA MAFB	1.98e-05	3	90	2	25500951
Pubmed	A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.	NR5A2 NR1H4	1.98e-05	3	90	2	11030332
Pubmed	Loss of MafA and MafB expression promotes islet inflammation.	MAFA MAFB	1.98e-05	3	90	2	31235823
Pubmed	MafB promotes atherosclerosis by inhibiting foam-cell apoptosis.	MAFB MAF	1.98e-05	3	90	2	24445679
Pubmed	The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male mice.	NR5A2 NR1H4	1.98e-05	3	90	2	17289919
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	ESYT2 ANAPC10 GTF3C1 MAP1S RADX EXD2 POLR2B UBR4 DTL GNB4 BRCC3 GNB1 DNAJC7	2.10e-05	1257	90	13	37317656
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ATP6V0A1 WIZ MAP1S UBR4 MKLN1 SENP6 BRCC3 SMG5 ZNF83 MERTK GNB1 DNAJC7 RFX5	2.64e-05	1285	90	13	35914814
Pubmed	Tagging genes with cassette-exchange sites.	ZNF462 POLR2B UBR4 MKLN1 SMG5 DNAJC7 DMXL1	2.72e-05	335	90	7	15741177
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MRPS31 ESYT2 ATP6V0A1 WDR36 UNC5B POLR2B UBR4 DDX42 ASPM NVL DBT DNAJC7 LACTB DMXL1	2.77e-05	1487	90	14	33957083
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	ZNF106 ESYT2 ANAPC10 WDR36 WIZ GTF3C1 POLR2B DDX42 U2AF2 BRCC3 LSM2 RFX5 PHC2	2.83e-05	1294	90	13	30804502
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	GTF3C1 TFB1M RC3H1 POLR2B PKP2 U2AF2 DHX57 BRCC3 LACTB	3.15e-05	615	90	9	31048545
Pubmed	Tshz1 Regulates Pancreatic β-Cell Maturation.	MAFA MAFB CLEC16A	3.70e-05	25	90	3	25918232
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	MRPS31 ANAPC10 GTF3C1 TFB1M EXD2 POLR2B U2AF2 DHX57 BRCC3 LSM2 DBT DNAJC7 LACTB	3.91e-05	1335	90	13	29229926
Pubmed	Mouse MafA, homologue of zebrafish somite Maf 1, contributes to the specific transcriptional activity through the insulin promoter.	MAFA MAFB	3.96e-05	4	90	2	14680841
Pubmed	SMS regulates the expression and function of P-gp and MRP2 in Caco-2 cells.	SGMS1 ABCC2	3.96e-05	4	90	2	27394416
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1	3.96e-05	4	90	2	1543505
Pubmed	Interleukin-18 Down-Regulates Multidrug Resistance-Associated Protein 2 Expression through Farnesoid X Receptor Associated with Nuclear Factor Kappa B and Yin Yang 1 in Human Hepatoma HepG2 Cells.	ABCC2 NR1H4	3.96e-05	4	90	2	26292095
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1	3.96e-05	4	90	2	12512701
Pubmed	Pax-6 and c-Maf functionally interact with the alpha-cell-specific DNA element G1 in vivo to promote glucagon gene expression.	MAFB MAF	3.96e-05	4	90	2	17901057
Pubmed	Maf and Mafb control mouse pallial interneuron fate and maturation through neuropsychiatric disease gene regulation.	MAFB MAF	3.96e-05	4	90	2	32452758
Pubmed	Elevated copper impairs hepatic nuclear receptor function in Wilson's disease.	NR5A2 NR1H4	3.96e-05	4	90	2	26241054
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	MRPS31 POLR2B UBR4 MKLN1 PKP2 DHX57	5.22e-05	253	90	6	29911972
Pubmed	The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.	MAFA MAFB MAF	5.24e-05	28	90	3	26554594
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	ZNF106 WDR36 MAP1S EXD2 SENP6 PKP2	6.33e-05	262	90	6	36880596
Pubmed	Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq.	GNB4 GNB1	6.59e-05	5	90	2	11294873
Pubmed	Inactivation of specific β cell transcription factors in type 2 diabetes.	MAFA MAFB	6.59e-05	5	90	2	23863625
Pubmed	Functional analysis of C-TAK1 substrate binding and identification of PKP2 as a new C-TAK1 substrate.	KSR1 PKP2	6.59e-05	5	90	2	12941695
Pubmed	Human transcription factor protein interaction networks.	MRPS31 ZNF462 WIZ GTF3C1 NFATC3 RADX RC3H1 UBR4 GNB4 SMG5 DBT DNAJC7 RFX5	7.80e-05	1429	90	13	35140242
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	ZNF106 WDR36 GTF3C1 NVL PKP2 U2AF2 LSM2	9.69e-05	410	90	7	26949251
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB4 GNB1	9.87e-05	6	90	2	16371464
Pubmed	The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.	ASPM CFHR5	9.87e-05	6	90	2	18541031
Pubmed	Challenges and Limitations of Targeting the Keap1-Nrf2 Pathway for Neurotherapeutics: Bach1 De-Repression to the Rescue.	MAFB MAF	9.87e-05	6	90	2	33897412
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB4 GNB1	9.87e-05	6	90	2	16884933
Pubmed	The Bach Family of Transcription Factors: A Comprehensive Review.	MAFB MAF	9.87e-05	6	90	2	27052415
Pubmed	Netrin1 deficiency activates MST1 via UNC5B receptor, promoting dopaminergic apoptosis in Parkinson's disease.	UNC5B MST1L	9.87e-05	6	90	2	32929029
Pubmed	Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.	POLR2B UBR4 DNAJC7	1.12e-04	36	90	3	35379950
Pubmed	Involvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesis.	NR5A2 NR1H4	1.38e-04	7	90	2	17895379
Pubmed	MafB Is Important for Pancreatic β-Cell Maintenance under a MafA-Deficient Condition.	MAFA MAFB	1.38e-04	7	90	2	31208980
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB4 GNB1	1.38e-04	7	90	2	10570481
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	ESYT2 ATP6V0A1 WDR36 GTF3C1 UBR4 U2AF2	1.67e-04	313	90	6	38270169
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	ESYT2 MAP1S TFB1M RADX POLR2B GNB1 DNAJC7 CLEC16A	1.80e-04	606	90	8	36538041
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB4 GNB1	1.84e-04	8	90	2	2328987
Pubmed	Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism.	ABCC2 NR1H4	1.84e-04	8	90	2	11279518
Pubmed	A set of Hox proteins interact with the Maf oncoprotein to inhibit its DNA binding, transactivation, and transforming activities.	MAFB MAF	1.84e-04	8	90	2	11036080
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZNF462 WIZ GTF3C1 RADX NVL SENP6 RFX5 SUV39H2	1.84e-04	608	90	8	36089195
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	MRPS31 ANAPC10 WDR36 GTF3C1 POLR2B ASPM U2AF2 DHX57 LSM2 DNAJC7	2.09e-04	971	90	10	33306668
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB4 GNB1	2.36e-04	9	90	2	10339615
Pubmed	MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation.	MAFB MAF	2.36e-04	9	90	2	36928411
Pubmed	Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas.	MAFA MAFB	2.36e-04	9	90	2	20025861
Pubmed	The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival.	MRPS31 MAFA DHX57 MAFB MAF	2.75e-04	220	90	5	31822558
Pubmed	Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord.	MAFA MAF	2.94e-04	10	90	2	31231191
Pubmed	Defining a Novel Role for the Pdx1 Transcription Factor in Islet β-Cell Maturation and Proliferation During Weaning.	MAFA MAFB	2.94e-04	10	90	2	28705881
Pubmed	The SWI/SNF chromatin remodelling complex regulates pancreatic endocrine cell expansion and differentiation in mice in vivo.	MAFA MAFB	2.94e-04	10	90	2	38958700
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB4 GNB1	2.94e-04	10	90	2	28334111
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB4 GNB1	2.94e-04	10	90	2	9733924
Pubmed	Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.	SLC5A5 COL6A3 GNB1	3.01e-04	50	90	3	24769233
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZNF462 ESYT2 SMG5 CLEC16A ARAP1	3.05e-04	225	90	5	12168954
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MRPS31 WDR36 TFB1M NR5A2 MKLN1 MROH7 DHX57	3.10e-04	496	90	7	31343991
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ZNF106 GTF3C1 MAP1S POLR2B DHX57 RMND1 DNAJC7	3.14e-04	497	90	7	36774506
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MRPS31 GTF3C1 UBR4 MAFA DTL DDX42 ASPM U2AF2 DHX57 ABCC2 GNB1 DNAJC7	3.40e-04	1442	90	12	35575683
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	ZNF462 WDR36 WIZ GTF3C1 DDX42 NVL U2AF2 GNB4 GNB1	3.51e-04	847	90	9	35850772
Pubmed	Plasticity and expanding complexity of the hepatic transcription factor network during liver development.	NR5A2 NR1H4	3.59e-04	11	90	2	16912278
Pubmed	Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.	MAFA MAFB	3.59e-04	11	90	2	20138042
Pubmed	The G protein subunit gene families.	GNB4 GNB1	3.59e-04	11	90	2	10644457
Pubmed	Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.	GNB4 GNB1	3.59e-04	11	90	2	34932372
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB4 GNB1	3.59e-04	11	90	2	25982117
Pubmed	Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways.	MAFA MAFB NR1H4 MAF	3.71e-04	130	90	4	19386638
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	MRPS31 GTF3C1 EXD2 UBR4 DHX57 DNAJC7 LACTB	3.88e-04	515	90	7	31617661
Pubmed	Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.	GNB4 GNB1	4.30e-04	12	90	2	34342229
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB4 GNB1	4.30e-04	12	90	2	20186915
Pubmed	Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.	ATP6V0A1 MKLN1	4.30e-04	12	90	2	20038947
Cytoband	Ensembl 112 genes in cytogenetic band chr7q11	SPDYE11 SPDYE17 SPDYE10 SPDYE13 SPDYE15 SPDYE8 SPDYE9 SPDYE12 SPDYE14	4.32e-09	271	92	9	chr7q11
Cytoband	7q11.23	SPDYE10 SPDYE8 SPDYE9 SPDYE14	4.54e-05	97	92	4	7q11.23
Cytoband	12q24.11	MYO1H RAD9B	2.01e-03	33	92	2	12q24.11
GeneFamily	Basic leucine zipper proteins	NRL MAFA MAFB MAF	2.85e-05	49	65	4	506
GeneFamily	Sterile alpha motif domain containing	SGMS1 SAMD15 ARAP1 PHC2	2.83e-04	88	65	4	760
GeneFamily	Speedy/RINGO cell cycle regulator family	SPDYE8 SPDYE9	8.21e-04	12	65	2	756
GeneFamily	WD repeat domain containing	WDR36 DTL GNB4 GNB1 DMXL1	2.50e-03	262	65	5	362
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRM PTPRZ1	2.56e-03	21	65	2	813
Coexpression	GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_UP	NFATC3 PTPRZ1 NR5A2 MERTK MYO16 NR1H4 MAF	4.23e-06	199	86	7	M8390
Coexpression	TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP	SGMS1 UNC5B DTL ASPM RMND1	4.56e-06	74	86	5	M4479
Coexpression	SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	TGFBI COL6A3 SRPX2 PTPRM MAFB MERTK ENPEP MAF	2.09e-05	352	86	8	M17471
Coexpression	AFFAR_YY1_TARGETS_DN	TGFBI COL6A3 TFB1M ASPM GNB4 SUV39H2 NR1H4	2.40e-05	260	86	7	M1471
Coexpression	AFFAR_YY1_TARGETS_DN	TGFBI COL6A3 TFB1M ASPM GNB4 SUV39H2 NR1H4	4.12e-05	283	86	7	MM1157
Coexpression	GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_UP	CFAP47 DDX42 GNB4 DBT LACTB DMXL1	5.18e-05	200	86	6	M8098
Coexpression	GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN	ATP6V0A1 PLAAT4 CD38 ARHGAP45 RFX5 ARAP1	5.18e-05	200	86	6	M7658
Coexpression	GAL_LEUKEMIC_STEM_CELL_UP	UNC5B UBR4 SENP6 DBT MAF	7.01e-05	130	86	5	M17428
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 SEMA6D ASPM PKP2 MAFB MYO16 MAF	1.02e-07	190	88	7	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL6A3 SRPX2 MERTK ENPEP NR1H4 MAF	8.74e-07	163	88	6	f1ec2625b52664308968b01d8e0275e1e0751480
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA6D ASPM PKP2 MAFB MYO16 MAF	1.88e-06	186	88	6	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA6D PTPRM ASPM PKP2 MYO16 MAF	2.00e-06	188	88	6	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM PTPRZ1 ASPM MAFB MYO16 MAF	2.13e-06	190	88	6	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|World / Lineage and Cell class	COL6A3 SRPX2 PTPRZ1 UNC5B MERTK MAF	2.26e-06	192	88	6	0703b8ec6960ff975ee5a2737054db67cab016b5
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TGFBI ZNF106 MAFB GNB4 MERTK PHC2	2.63e-06	197	88	6	9838dbd1623babf8de7e9126a28fe5d3666bce42
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF462 SEMA6D UNC5B PKP2 MYO16 MAF	2.86e-06	200	88	6	ca5401b76ab014080914bf78042d368cf318effa
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PTPRM PTPRZ1 ASPM MAFB MYO16 MAF	2.86e-06	200	88	6	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1--L2-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF462 SEMA6D UNC5B PKP2 MYO16 MAF	2.86e-06	200	88	6	70c47d3bbe67d88c5b9dff99c33a603d25fa2ab0
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF462 PTPRM UNC5B PKP2 MYO16 MAF	2.86e-06	200	88	6	e90155498397524b812c46f2412320230b445bb6
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)-CA1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ZNF462 SEMA6D UNC5B PKP2 MYO16 MAF	2.86e-06	200	88	6	40286010bd17cf9e34ecd5440953b072ebfae208
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TGFBI COL6A3 WDR36 NFATC3 ENPEP	2.21e-05	170	88	5	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGFBI SEMA6D PTPRM MAFB MERTK	2.75e-05	178	88	5	6c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFBI UNC5B DTL GNB4 NR1H4	2.83e-05	179	88	5	ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGFBI GARIN4 MAFB MERTK MAF	2.90e-05	180	88	5	6f8fa9fa91cd25b92584972bb34d90c483222f52
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM PTPRZ1 ASPM MYO16 MAF	2.98e-05	181	88	5	af92b8b7f455210dab502ef6964f3a0162180759
ToppCell	3'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6D ABCC2 ENPEP NR1H4 MAF	3.22e-05	184	88	5	ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ASPM PKP2 MAFB MYO16 MAF	3.22e-05	184	88	5	ae0a77e3e520a246b17776bb19503519636b02ee
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	TGFBI COL6A3 UNC5B NR5A2 GNB4	3.31e-05	185	88	5	427176ad9ab8d9511200fb0a132cfd1e835fe35c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L6_LAMP5_C1QL2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM UNC5B PKP2 MYO16 MAF	3.31e-05	185	88	5	6e7fefdd65d30abaffb26b92b0d04e1630d262ad
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM PTPRZ1 MAFB MYO16 MAF	3.31e-05	185	88	5	f4ac62009c0ad3346e71b809e17727303c4df153
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6D ABCC2 ENPEP NR1H4 MAF	3.40e-05	186	88	5	bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGFBI MAFB GNB4 ABCC2 MERTK	3.40e-05	186	88	5	f73cb91e74a806858650ae97f543fc779ba4cff8
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono-Mono_anti-infl\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TGFBI MAFB GNB4 ABCC2 MERTK	3.40e-05	186	88	5	8694ca16c9780729f4fba67ba20e35745f1eb4e9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM PTPRZ1 ASPM MYO16 MAF	3.48e-05	187	88	5	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SEMA6D ABCC2 ENPEP NR1H4 MAF	3.48e-05	187	88	5	9042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTPRZ1 RADX DTL ASPM SUV39H2	3.48e-05	187	88	5	a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA6D PTPRM PTPRZ1 UNC5B MYO16	3.57e-05	188	88	5	ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL6A3 SRPX2 ENPEP ARAP1 MAF	3.57e-05	188	88	5	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM MAFB MYO16 MAF	3.57e-05	188	88	5	8de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM MAFB MYO16 MAF	3.66e-05	189	88	5	99a13b1b669b0cd36e3096632351d9ade25d1173
ToppCell	Monocytes-Tissue-resident_macrophages\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TGFBI UNC5B PKP2 MAFB GNB4	3.76e-05	190	88	5	07215e8f292cb54c670037aaf28393cddbe5548c
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM MAFB MYO16 MAF	3.76e-05	190	88	5	8c9c230a509afaeee50644153974a5642b01a2b8
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM MAFB MYO16 MAF	3.76e-05	190	88	5	0acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM MAFB MYO16 MAF	3.76e-05	190	88	5	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A3 SRPX2 ENPEP ARAP1 MAF	3.85e-05	191	88	5	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Cycling_Myeloid-Mac\|GI_small-bowel / Manually curated celltypes from each tissue	TGFBI DTL ASPM MAFB GNB4	3.85e-05	191	88	5	c3944332c5226b0113f8aa9ac07837b755606c6c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM MAFB MYO16 MAF	3.85e-05	191	88	5	782bc7946417549ffd39e5b596db659436fa01ba
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 PTPRM PKP2 MYO16 MAF	3.95e-05	192	88	5	f6ec683b2133b3095a1fcc06ca8605cf38f774b5
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM UNC5B PKP2 MYO16 MAF	3.95e-05	192	88	5	342842378c20267c5044bdd622515e8b9f895623
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A3 SRPX2 ENPEP ARAP1 MAF	3.95e-05	192	88	5	2802fae55683345ff94a1ecf73b6fbee4f17481e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 PTPRM PKP2 MYO16 MAF	3.95e-05	192	88	5	690b3d17c481159bc96b8bc7f6a66b51343ee858
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A3 SRPX2 ENPEP ARAP1 MAF	3.95e-05	192	88	5	0afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A3 SRPX2 ENPEP ARAP1 MAF	3.95e-05	192	88	5	e79f2253e084a9ab9afcaf7ec42a5012ade42d36
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM PKP2 MAFB MYO16 MAF	3.95e-05	192	88	5	bf1943715085c4124b1675888b0615c9500ec888
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM PKP2 MAFB MAF	4.05e-05	193	88	5	9f9eb241b0b82a6f12de6921c3acf6fed7cf65bb
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 PTPRM PKP2 MYO16 MAF	4.05e-05	193	88	5	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.05e-05	193	88	5	8d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.05e-05	193	88	5	1b2cc627b2aa002b442358bd1188d470e67ce7d9
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 PTPRM PKP2 MYO16 MAF	4.05e-05	193	88	5	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM ASPM MAFB MYO16 MAF	4.05e-05	193	88	5	c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCell	COVID-19-Heart-Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	TGFBI MAFB MERTK ARHGAP45 MAF	4.15e-05	194	88	5	f09675cd472200363c458952f00d2e41990800ee
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.15e-05	194	88	5	f15e81ff12525523c62d13105cf264ea72205e2e
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-innate_lymphocytic\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GTF3C1 PLAAT4 CD38 DTL ASPM	4.15e-05	194	88	5	8bfd7c5be518b81b17913139bcb3ebea01f48dd5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 PTPRM PKP2 MYO16 MAF	4.15e-05	194	88	5	6ac759828c41ffa974ee82842162caa959351dd1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Mesenchymal-choroid_plexus/mesenchymal-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	TGFBI COL6A3 SRPX2 UNC5B NR5A2	4.15e-05	194	88	5	8ac0b63c7a89e5ff78bbdd8dd1960aa2422a85f7
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Mesenchymal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	TGFBI COL6A3 SRPX2 UNC5B NR5A2	4.15e-05	194	88	5	4bafe26573cb2ff966f4a688c5769da598eea415
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZNF462 PTPRM PKP2 MYO16 MAF	4.15e-05	194	88	5	5d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GTF3C1 PLAAT4 CD38 DTL ASPM	4.15e-05	194	88	5	f0707601883b234ed477c7704ca9a88efaefc3fd
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TGFBI MAFB MERTK ARHGAP45 MAF	4.15e-05	194	88	5	58046894446cb250814252a23f60fdd59c114d77
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM PKP2 MAFB MYO16 MAF	4.15e-05	194	88	5	4f758718a1233c25c25d99fc1b7b06f906b8b0a2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRM PKP2 MAFB MYO16 MAF	4.15e-05	194	88	5	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.25e-05	195	88	5	b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.25e-05	195	88	5	1c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCell	PND07-Mesenchymal-Mesenchymal_structural\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.25e-05	195	88	5	2f9a274b26fc528a85f50933ec2f4db1dc9da0ca
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DTL PKP2 GNB4 RFX5 NR1H4	4.36e-05	196	88	5	53d1f9e9f009d1417a19ca6f9a83ecdf7776ef88
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.36e-05	196	88	5	97e26622d9582b092c18ff5b7e957818f99d9631
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.36e-05	196	88	5	f429f045ba45e24717963315832150b12a115bfa
ToppCell	5'-Adult-SmallIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TGFBI PLAAT4 CD38 MAFB MERTK	4.36e-05	196	88	5	008e7593ab26988b957673f863bdd017516281ae
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS1 CD38 MERTK ENPEP MAF	4.46e-05	197	88	5	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGMS1 CD38 MERTK ENPEP MAF	4.46e-05	197	88	5	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	mild-dn_T\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ESYT2 CD38 NR5A2 DBT ZNF831	4.46e-05	197	88	5	07a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCell	COVID-19\|World / Condition, Lineage and Cell class	PLAAT4 CD38 MAFB MERTK MAF	4.46e-05	197	88	5	228f641d79282cc3dc51b95a1f4b0cccfc200735
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TGFBI MAFB GNB4 MERTK MAF	4.46e-05	197	88	5	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TGFBI MAFB GNB4 MERTK MAF	4.46e-05	197	88	5	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	control-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	TGFBI KSR1 MAFB GNB4 ARAP1	4.57e-05	198	88	5	35499a5231818e3432cf69b5c4a58c02f7771db8
ToppCell	E18.5-Mesenchymal\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TGFBI COL6A3 SRPX2 ENPEP MAF	4.57e-05	198	88	5	a16aa41eab2e297e56de43c22c355df0f79315da
ToppCell	10x3'2.3-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TGFBI MAFB GNB4 MERTK MAF	4.57e-05	198	88	5	9a89083280d4253f282300cdf1e61746d1f32407
ToppCell	mLN-B_cell-B_cell_IgA_Plasma\|B_cell / Region, Cell class and subclass	GARIN4 SRPX2 MERTK MYO16 MAF	4.68e-05	199	88	5	09494953bc7fff63cf2763ea89fca7abb97c186f
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.68e-05	199	88	5	2cec0e370ee9bb3c88a7acb5519e9ea8ddb399bc
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 SRPX2 ENPEP ARAP1 MAF	4.68e-05	199	88	5	9e87b64e16d595701c3beb07aa835afe3330bd10
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1--L4-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PTPRM PTPRZ1 ASPM MYO16 MAF	4.79e-05	200	88	5	4a426ef88376d8bb2b9dc50aa06e7b9fc50ecc9c
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SEMA6D PTPRM PTPRZ1 UNC5B MYO16	4.79e-05	200	88	5	c74bc12e13d002dedaaf75a2244ec111e47524e1
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SEMA6D PTPRM PTPRZ1 UNC5B MYO16	4.79e-05	200	88	5	ead9eb579bb25fde05fc15602e3d05ab6617f7ac
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-MC4R\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SEMA6D PTPRM UNC5B PKP2 NR1H4	4.79e-05	200	88	5	c1797542541747b524c9c22c723d24c8d027d486
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB--L2-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PTPRM PTPRZ1 MAFB MYO16 MAF	4.79e-05	200	88	5	5ec469267747dce3601c1d8ad01af89fa5b29acc
ToppCell	Transverse-Dendritic_cell-cycling_DCs\|Transverse / Region, Cell class and subclass	TGFBI UNC5B ASPM MAFB GNB4	4.79e-05	200	88	5	f588d8889f351c797963616a3575fa43efd46b9a
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PTPRM PTPRZ1 MAFB MYO16 MAF	4.79e-05	200	88	5	e79d93d55b25804f2608185168da472301b6ebca
ToppCell	Transverse-(5)_Dendritic_cell-(52)_cycling_DCs\|Transverse / shred on region, Cell_type, and subtype	TGFBI UNC5B ASPM MAFB GNB4	4.79e-05	200	88	5	51e643d48b5e97a0e117b578a6ea7d429c6cdd1e
ToppCell	COVID-19-Myeloid-MoAM2,_CCL18\|COVID-19 / Condition, Lineage and Cell class	TGFBI ATP6V0A1 MAFB MERTK MAF	4.79e-05	200	88	5	b0a50622d00335843efad86bc56a1e910019984b
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PTPRM PTPRZ1 ASPM MYO16 MAF	4.79e-05	200	88	5	fbeee1c16ac0a7fe28d90491c8b079f21ce80bdc
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SULF1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PTPRM PTPRZ1 ASPM MYO16 MAF	4.79e-05	200	88	5	c6eda342ea0cb37d71d89dbb8d11e819e0745172
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST-MC4R-L1-2\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SEMA6D PTPRM UNC5B PKP2 NR1H4	4.79e-05	200	88	5	a0cc84add181109bb66ba9d49c732e1790222c96
ToppCell	Neuronal-Inhibitory-iB-iB_3(PVALB-SST)-FRZB-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PTPRM PTPRZ1 MAFB MYO16 MAF	4.79e-05	200	88	5	320d5a3a1e7da2fa8f1a164e29e180ec8ac9889c
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA6D ASPM MROH7 MYO16	1.14e-04	126	88	4	69b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEMA6D ASPM MROH7 MYO16	1.14e-04	126	88	4	6cb89754010d64875e115da6c5805efac7a4a82d
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC5A5 SEMA6D MAFB MYO16	1.25e-04	129	88	4	6bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TGFBI PTPRM RADX MAF	1.29e-04	130	88	4	60e28d452d0e2af768459ba8dbe998117c94a251
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Col15a1_Pde1a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PTPRZ1 UNC5B GNB4 MAF	1.29e-04	130	88	4	56b9c3325e011f1dbaf9efc71bd6e1af4f96fda6
Disease	Cholestasis of pregnancy	ABCC2 NR1H4	2.22e-04	8	84	2	C0268318
Disease	rhinitis	WDR36 CLEC16A	1.06e-03	17	84	2	EFO_0008521
Disease	Non-alcoholic Fatty Liver Disease	NR5A2 ABCC2 NR1H4	1.06e-03	70	84	3	C0400966
Disease	Nonalcoholic Steatohepatitis	NR5A2 ABCC2 NR1H4	1.06e-03	70	84	3	C3241937
Disease	coagulation factor measurement	ASPM CFHR5	1.47e-03	20	84	2	EFO_0004634
Disease	total blood protein measurement	NFATC3 MAFB ARHGAP45 CLEC16A ARAP1 MAF	1.80e-03	449	84	6	EFO_0004536
Disease	vital capacity	ZNF106 COL6A3 ANAPC10 UNC5B POLR2B NR5A2 GNB1 C3orf49 MYO16 MAF	2.66e-03	1236	84	10	EFO_0004312

Protein segments in the cluster

Peptide	Gene	Start	Entry
VQKVIGTNRKYFTNC	TGFBI	51	Q15582
EIKRYFCRAGVKSIQ	ESYT2	281	A0FGR8
YAQRRLKKRGIFCIS	ATP13A4	456	Q4VNC1
QLTKFLYGFCKQSRR	GYS2	566	P54840
LYGFCKQSRRQRIIQ	GYS2	571	P54840
VRLYNTESQSFRKKC	DTL	76	Q9NZJ0
RKGFTYVFDLCQRQQ	DMXL1	2906	Q9Y485
VKIIQGCFYTKLERT	ASPM	2981	Q8IZT6
ISKRNIQFSCKNIYR	CD38	266	P28907
RSSCINLYGKVVQKL	MROH7	1101	Q68CQ1
VQLLYRASCFKVTKR	RC3H1	246	Q5TC82
QSKYCYSGIRRKTLV	RFX5	156	P48382
RVIQYLTSNKCGKYV	NVL	16	O15381
FRRSITKNAVYKCKN	NR1H4	161	Q96RI1
TRSDKCKVVIQFFYR	RAD9B	111	Q6WBX8
CKVVIQFFYRHGIKR	RAD9B	116	Q6WBX8
ISRVSCLYNEKRIGQ	RADX	131	Q6NSI4
SRNAGKLICVRYFQT	DBT	11	P11182
CTFIQIFRYTGIRNK	OVOS1	1091	Q6IE37
YRVNGVKTRVEKLCQ	ARHGAP45	796	Q92619
VRALCYVISGQDQRK	MAP1S	971	Q66K74
LKNRGYAQSCRYKRV	MAFB	246	Q9Y5Q3
TLKNRGYAQSCRFKR	MAFA	261	Q8NHW3
LKNRGYAQSCRFKRV	MAF	296	O75444
SVKNCFIRGSVVRYV	LSM2	56	Q9Y333
VVNYIAKKSFCRRAI	MERTK	546	Q12866
QYRGTVSKTRKGVQC	MST1L	361	Q2TV78
FCERKQQLTGARIYT	MYO16	561	Q9Y6X6
KEYEKQVRNGRLFCT	SPINK5	226	Q9NQ38
KQQLRLKFATGRSCY	GARIN4	136	Q8IYT1
VVERKQTYGSCRKQR	LACTB	466	P83111
CKRFGKAYNLRSVAV	DDX42	346	Q86XP3
VVCGKRDSYIRKNVI	EXD2	421	Q9NVH0
VRYICKQRQCKLSVA	KSR1	81	Q8IVT5
TLKNRGYAQACRSKR	NRL	166	P54845
CSIYNLKTREGNVRV	GNB4	121	Q9HAV0
YFQLCFKLGVKVRTA	ABCC2	381	Q92887
SGDQVQVRRCFEYKK	ENPEP	151	Q07075
ITNLVEKGRRKCDQY	PTPRZ1	1826	P23471
IQFRRKTTVKTLCIY	ANAPC10	66	Q9UM13
YRKVGQCRRFQQLKK	C3orf49	16	Q96BT1
CSIYNLKTREGNVRV	GNB1	121	P62873
SIAYGRCQKIGRQKL	CLPSL1	101	A2RUU4
VQKLSRYGFNTERCQ	DHX57	186	Q6P158
QRVILQAKCKGYFFV	COL6A3	2756	P12111
FYKLQGSVTVTCRNK	CFHR5	481	Q9BXR6
LYCNRGTVNSKLRKL	DNAJC7	296	Q99615
QYKECFITNFISGRK	SAMD15	561	Q9P1V8
KTCFRGTVRLYNRQN	CFAP47	866	Q6ZTR5
NVVNTTKRDAGKYRC	PTPRM	246	P28827
CKGFFKRTVQNNKRY	NR5A2	106	O00482
IQRYFGTNSVICSKK	MRPS31	56	Q92665
GNRYIRCQKEVGKSF	SMG5	916	Q9UPR3
KNRCLYVFGGQRSKT	MKLN1	466	Q9UL63
SVKYVYKLTIGCQRV	RGP1	131	Q92546
FVTQLRYGKSRCKQV	PLAAT4	116	Q9UL19
RARKNCSQIALFRKY	SPDYE10	211	P0DUX0
RARKNCSQIALFRKY	SPDYE11	211	P0DTA3
RARKNCSQIALFRKY	SPDYE8	211	P0DUD1
LNQEGYKFCKIRVRS	POLR2B	911	P30876
YDKTCQFLSIGRRVK	RMND1	386	Q9NWS8
EKVVQNVFQFRRKYC	TFB1M	246	Q8WVM0
LVKFVGNIYTLKCRF	WIZ	1586	O95785
KNTKTGRVLYTCFQS	BRCC3	161	P46736
IYRKCGQTSKTQRLL	ARAP1	991	Q96P48
FLNILRQKSGRYVCV	CLEC16A	81	Q2KHT3
RQKSGRYVCVQLLQT	CLEC16A	86	Q2KHT3
AKRYNVGCTKRVGLF	PHC2	666	Q8IXK0
VQRYVACRTEKQAKL	SLC5A5	266	Q92911
RAYNRASCKFIVKVQ	SRPX2	246	O60687
RARKNCSQIALFRKY	SPDYE12	211	P0DUX1
RARKNCSQIALFRKY	SPDYE13	211	A0A494C0Z2
RARKNCSQIALFRKY	SPDYE14	211	P0DUD3
RARKNCSQIALFRKY	SPDYE15	211	P0DUD4
RARKNCSQIALFRKY	SPDYE17	211	P0DUD2
NRIVQKGTQYSLCIF	SUV39H2	241	Q9H5I1
YLCNGKRKKSQSQRF	NFATC3	681	Q12968
KYKSIISRRFFCIVG	SGMS1	206	Q86VZ5
IKRKVQQKRHCSTYQ	SENP6	201	Q9GZR1
VRQLKVRNNTCKVYS	PKD2L2	131	Q9NZM6
ANYTCVAKNIVAKRR	UNC5B	221	Q8IZJ1
NRVKKICEGFRASLY	ATP6V0A1	231	Q93050
GRKFANRVVVTKYCD	U2AF2	451	P26368
VCRSKLSKYLQGVVF	ZNF462	2286	Q96JM2
DICGKVFNSKRYVAR	ZNF765	246	Q7L2R6
RARKNCSQIALFRKY	SPDYE9	211	A0A494C191
ATEKFYTVLKCNNRR	VWA3B	1126	Q502W6
KRYKGNFLQSCVQLR	ZNF831	1291	Q5JPB2
QGSCRYFKERKNITN	GTF3C1	111	Q12789
NLGKAVYSRVARICK	SEMA6D	246	Q8NFY4
SYRKACVLQRQRKGS	UBR4	541	Q5T4S7
GCFGSRSRKVKEQYQ	PKP2	646	Q99959
KTVRVYNLVSRKCIG	ZNF106	1551	Q9H2Y7
NKCGKVFSRNSYLVQ	ZNF83	236	P51522
ALKRRFYVTTCVGKS	WDR36	91	Q8NI36
QLVARIQATYKRCLG	MYO1H	706	Q8N1T3