Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribose phosphate diphosphokinase activity	PRPS2 PRPS1L1 PRPS1	2.67e-06	5	130	3	GO:0004749
GeneOntologyMolecularFunction	diphosphotransferase activity	PRPS2 PRPS1L1 PRPS1	5.32e-06	6	130	3	GO:0016778
GeneOntologyMolecularFunction	complement component C1q complex binding	CALR C4A C4B	3.13e-05	10	130	3	GO:0001849
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNA6 CHRNA1 CHRNA3	1.72e-04	17	130	3	GO:0022848
GeneOntologyMolecularFunction	ATP-dependent activity	KIF13B KIF23 CECR2 SMARCAL1 NLRP1 RFC5 MYO5C DHX15 DNAH17 KIF14 MACF1 TOP2A AQR	1.88e-04	614	130	13	GO:0140657
GeneOntologyMolecularFunction	magnesium ion binding	PRPS2 ME1 OPA1 PRPS1L1 HACL1 RP2 TOP2A PRPS1	2.17e-04	247	130	8	GO:0000287
GeneOntologyMolecularFunction	low-affinity IgG receptor activity	FCGR3A FCGR3B	2.50e-04	4	130	2	GO:0019772
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRNA6 CHRNA1 CHRNA3	4.34e-04	23	130	3	GO:0015464
GeneOntologyMolecularFunction	opsonin binding	CALR C4A C4B	5.58e-04	25	130	3	GO:0001846
GeneOntologyMolecularFunction	IgE receptor activity	FCGR3A FCGR3B	6.20e-04	6	130	2	GO:0019767
GeneOntologyMolecularFunction	IgE binding	FCGR3A FCGR3B	8.65e-04	7	130	2	GO:0019863
GeneOntologyMolecularFunction	IgG receptor activity	FCGR3A FCGR3B	8.65e-04	7	130	2	GO:0019770
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF13B KIF23 MYO5C DNAH17 KIF14	1.05e-03	118	130	5	GO:0003774
GeneOntologyMolecularFunction	microtubule motor activity	KIF13B KIF23 DNAH17 KIF14	1.13e-03	70	130	4	GO:0003777
GeneOntologyMolecularFunction	metalloendopeptidase activity	PAPPA2 CLCA4 ACE ADAMTS7 MMP15	1.13e-03	120	130	5	GO:0004222
GeneOntologyMolecularFunction	complement binding	CALR C4A C4B	1.16e-03	32	130	3	GO:0001848
GeneOntologyBiologicalProcess	5-phosphoribose 1-diphosphate metabolic process	PRPS2 PRPS1L1 PRPS1	4.83e-06	6	130	3	GO:0046391
GeneOntologyBiologicalProcess	5-phosphoribose 1-diphosphate biosynthetic process	PRPS2 PRPS1L1 PRPS1	4.83e-06	6	130	3	GO:0006015
GeneOntologyBiologicalProcess	perforin production	FCGR3A FCGR3B	3.94e-05	2	130	2	GO:0035944
GeneOntologyBiologicalProcess	microtubule-based movement	KIF13B KIF23 IFT57 APOB OPA1 MEGF8 DNAH17 VPS13A KIF14 DNAI7 SPAG17 HYDIN	6.83e-05	493	130	12	GO:0007018
GeneOntologyCellularComponent	ribose phosphate diphosphokinase complex	PRPS2 PRPS1L1 PRPS1	2.55e-06	5	134	3	GO:0002189
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRNA6 CHRNA1 CHRNA3	1.96e-04	18	134	3	GO:0005892
GeneOntologyCellularComponent	Fc-gamma receptor III complex	FCGR3A FCGR3B	2.43e-04	4	134	2	GO:0033001
GeneOntologyCellularComponent	dendrite terminus	IFT57 RGS7 SMO	2.71e-04	20	134	3	GO:0044292
GeneOntologyCellularComponent	transferase complex	CUL4B PRPS2 SETD1A INSR CUL9 CBX4 PRPS1L1 GLMN PIGC MEGF8 KLHL15 MSL3 MGA TAF1L ANAPC4 PRPS1	4.52e-04	963	134	16	GO:1990234
GeneOntologyCellularComponent	axon	KIF13B BIN1 NRCAM PCLO INSR OPA1 CNTN6 NRP2 NEK3 TENM3 PTPRK SACS C4A SMO C4B	6.00e-04	891	134	15	GO:0030424
GeneOntologyCellularComponent	axonemal central apparatus	SPAG17 HYDIN	6.02e-04	6	134	2	GO:1990716
Domain	PRPP_SYNTHASE	PRPS2 PRPS1L1 PRPS1	3.30e-07	3	130	3	PS00114
Domain	PRib_PP_synth_CS	PRPS2 PRPS1L1 PRPS1	3.30e-07	3	130	3	IPR000842
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.31e-06	4	130	3	IPR029423
Domain	LRRC37AB_C	LRRC37A3 LRRC37A2 LRRC37A	1.31e-06	4	130	3	PF14914
Domain	LRRC37_N	LRRC37A3 LRRC37A2 LRRC37A	1.31e-06	4	130	3	IPR032754
Domain	LRRC37	LRRC37A3 LRRC37A2 LRRC37A	1.31e-06	4	130	3	PF15779
Domain	LRRC37A/B-like	LRRC37A3 LRRC37A2 LRRC37A	1.31e-06	4	130	3	IPR015753
Domain	Pribosyltran_N	PRPS2 PRPS1L1 PRPS1	3.26e-06	5	130	3	PF13793
Domain	Pribosyl_synth	PRPS2 PRPS1L1 PRPS1	3.26e-06	5	130	3	PF14572
Domain	Rib-P_diPkinase	PRPS2 PRPS1L1 PRPS1	3.26e-06	5	130	3	IPR005946
Domain	Pribosyltran_N	PRPS2 PRPS1L1 PRPS1	3.26e-06	5	130	3	IPR029099
Domain	FN3	PAPPA2 NRCAM SPEG INSR CNTN6 LIFR CSF2RB PTPRK	4.62e-05	185	130	8	SM00060
Domain	Pribosyltran	PRPS2 PRPS1L1 PRPS1	5.22e-05	11	130	3	PF00156
Domain	PRTase-like	PRPS2 PRPS1L1 PRPS1	6.92e-05	12	130	3	IPR029057
Domain	PRibTrfase_dom	PRPS2 PRPS1L1 PRPS1	6.92e-05	12	130	3	IPR000836
Domain	-	PRPS2 PRPS1L1 PRPS1	6.92e-05	12	130	3	3.40.50.2020
Domain	FN3_dom	PAPPA2 NRCAM SPEG INSR CNTN6 LIFR CSF2RB PTPRK	1.09e-04	209	130	8	IPR003961
Domain	fn3	NRCAM SPEG INSR CNTN6 LIFR CSF2RB PTPRK	1.40e-04	162	130	7	PF00041
Domain	Nicotinic_acetylcholine_rcpt	CHRNA6 CHRNA1 CHRNA3	1.73e-04	16	130	3	IPR002394
Domain	NAP_family	SET TSPY26P SETSIP	2.09e-04	17	130	3	IPR002164
Domain	NAP	SET TSPY26P SETSIP	2.09e-04	17	130	3	PF00956
Domain	Anaphylatoxin_comp_syst	C4A C4B	4.74e-04	5	130	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	4.74e-04	5	130	2	IPR001840
Domain	FN3	NRCAM SPEG INSR CNTN6 LIFR CSF2RB PTPRK	4.91e-04	199	130	7	PS50853
Domain	-	CHRNA6 CHRNA1 CHRNA3	5.27e-04	23	130	3	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRNA6 CHRNA1 CHRNA3	5.27e-04	23	130	3	IPR027361
Domain	ARM-type_fold	CAND2 DOCK9 CUL9 APOB ARMCX5 MAP3K1 PPP2R5D RRP12 IPO13	6.18e-04	339	130	9	IPR016024
Domain	Kinesin_assoc	KIF13B KIF14	7.08e-04	6	130	2	PF16183
Domain	Kinesin_assoc	KIF13B KIF14	7.08e-04	6	130	2	IPR032405
Domain	-	PAPPA2 NRCAM SPEG INSR LAIR1 CNTN6 LIFR CSF1R CSF2RB PTPRK FCGR3A FCGR3B IGSF3	7.33e-04	663	130	13	2.60.40.10
Domain	ANATO	C4A C4B	9.87e-04	7	130	2	SM00104
Domain	Cullin_CS	CUL4B CUL9	9.87e-04	7	130	2	IPR016157
Domain	ANAPHYLATOXIN_2	C4A C4B	9.87e-04	7	130	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	9.87e-04	7	130	2	PS01177
Domain	ANATO	C4A C4B	9.87e-04	7	130	2	PF01821
Domain	Anaphylatoxin/fibulin	C4A C4B	9.87e-04	7	130	2	IPR000020
Domain	Ig-like_fold	PAPPA2 NRCAM SPEG INSR LAIR1 CNTN6 LIFR CSF1R CSF2RB PTPRK FCGR3A FCGR3B IGSF3	1.30e-03	706	130	13	IPR013783
Domain	Cullin_neddylation_domain	CUL4B CUL9	1.31e-03	8	130	2	IPR019559
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	1.31e-03	8	130	2	IPR019565
Domain	Cullin_Nedd8	CUL4B CUL9	1.31e-03	8	130	2	PF10557
Domain	Cullin_Nedd8	CUL4B CUL9	1.31e-03	8	130	2	SM00884
Domain	Thiol-ester_cl	C4A C4B	1.31e-03	8	130	2	PF10569
Domain	MacrogloblnA2_CS	C4A C4B	1.31e-03	8	130	2	IPR019742
Domain	Cullin_homology	CUL4B CUL9	1.68e-03	9	130	2	IPR016158
Domain	Tyr_Pase_AS	DUSP8 MTMR14 PTPRK MTMR3	1.68e-03	73	130	4	IPR016130
Domain	A2M	C4A C4B	2.09e-03	10	130	2	PF00207
Domain	A2M_N_2	C4A C4B	2.09e-03	10	130	2	IPR011625
Domain	A2M_comp	C4A C4B	2.09e-03	10	130	2	IPR011626
Domain	Cullin	CUL4B CUL9	2.09e-03	10	130	2	PF00888
Domain	A2M_recep	C4A C4B	2.09e-03	10	130	2	PF07677
Domain	A2M_comp	C4A C4B	2.09e-03	10	130	2	PF07678
Domain	A2M_N	C4A C4B	2.09e-03	10	130	2	PF01835
Domain	A2M_N	C4A C4B	2.09e-03	10	130	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	2.09e-03	10	130	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	2.09e-03	10	130	2	PS00477
Domain	CULLIN_2	CUL4B CUL9	2.09e-03	10	130	2	PS50069
Domain	A2M_N_2	C4A C4B	2.09e-03	10	130	2	PF07703
Domain	Cullin_N	CUL4B CUL9	2.09e-03	10	130	2	IPR001373
Domain	Macroglobln_a2	C4A C4B	2.09e-03	10	130	2	IPR001599
Domain	CULLIN_1	CUL4B CUL9	2.09e-03	10	130	2	PS01256
Domain	-	SIRT7 HACL1	2.54e-03	11	130	2	3.40.50.1220
Domain	IG	NRCAM SPEG LAIR1 CNTN6 CSF1R PTPRK FCGR3A FCGR3B IGSF3	2.76e-03	421	130	9	SM00409
Domain	Ig_sub	NRCAM SPEG LAIR1 CNTN6 CSF1R PTPRK FCGR3A FCGR3B IGSF3	2.76e-03	421	130	9	IPR003599
Domain	LRR	LRWD1 LRRC37A3 LRRC37A2 KERA NLRP1 LRRC37A	2.85e-03	201	130	6	PS51450
Domain	Kinesin_motor_CS	KIF13B KIF23 KIF14	2.90e-03	41	130	3	IPR019821
Domain	DHS-like_NAD/FAD-binding_dom	SIRT7 HACL1	3.03e-03	12	130	2	IPR029035
Domain	Rossmann-like_a/b/a_fold	NADSYN1 PCYT2 VARS1	3.32e-03	43	130	3	IPR014729
Domain	-	NADSYN1 PCYT2 VARS1	3.32e-03	43	130	3	3.40.50.620
Domain	Kinesin-like_fam	KIF13B KIF23 KIF14	3.32e-03	43	130	3	IPR027640
Domain	-	KIF13B KIF23 KIF14	3.54e-03	44	130	3	3.40.850.10
Domain	Kinesin	KIF13B KIF23 KIF14	3.54e-03	44	130	3	PF00225
Domain	KISc	KIF13B KIF23 KIF14	3.54e-03	44	130	3	SM00129
Domain	KINESIN_MOTOR_1	KIF13B KIF23 KIF14	3.54e-03	44	130	3	PS00411
Domain	Kinesin_motor_dom	KIF13B KIF23 KIF14	3.54e-03	44	130	3	IPR001752
Domain	KINESIN_MOTOR_2	KIF13B KIF23 KIF14	3.54e-03	44	130	3	PS50067
Domain	Neurotransmitter_ion_chnl_CS	CHRNA6 CHRNA1 CHRNA3	3.78e-03	45	130	3	IPR018000
Domain	-	DUSP8 MTMR14 PTPRK MTMR3	3.90e-03	92	130	4	3.90.190.10
Domain	Neur_chan_memb	CHRNA6 CHRNA1 CHRNA3	4.02e-03	46	130	3	PF02932
Domain	Galactose-bd-like	NTNG1 CUL9 NRP2 PTPRK	4.22e-03	94	130	4	IPR008979
Domain	Neurotrans-gated_channel_TM	CHRNA6 CHRNA1 CHRNA3	4.27e-03	47	130	3	IPR006029
Domain	-	CHRNA6 CHRNA1 CHRNA3	4.27e-03	47	130	3	2.70.170.10
Domain	Neur_chan_LBD	CHRNA6 CHRNA1 CHRNA3	4.27e-03	47	130	3	PF02931
Domain	NEUROTR_ION_CHANNEL	CHRNA6 CHRNA1 CHRNA3	4.27e-03	47	130	3	PS00236
Domain	Neur_channel	CHRNA6 CHRNA1 CHRNA3	4.27e-03	47	130	3	IPR006201
Domain	Neur_chan_lig-bd	CHRNA6 CHRNA1 CHRNA3	4.27e-03	47	130	3	IPR006202
Domain	LRR_1	LRWD1 LRRC37A3 LRRC37A2 KERA NLRP1 LRRC37A	4.34e-03	219	130	6	PF00560
Domain	ZINC_PROTEASE	PAPPA2 ACE ADAMTS7 MMP15	4.89e-03	98	130	4	PS00142
Domain	Prot-tyrosine_phosphatase-like	DUSP8 MTMR14 PTPRK MTMR3	5.07e-03	99	130	4	IPR029021
Domain	CarboxyPept-like_regulatory	CPD TENM3	6.11e-03	17	130	2	IPR008969
Domain	MAM	NRP2 PTPRK	6.11e-03	17	130	2	SM00137
Domain	C345C	C4A C4B	6.11e-03	17	130	2	SM00643
Domain	MAM	NRP2 PTPRK	6.84e-03	18	130	2	PF00629
Domain	MAM_dom	NRP2 PTPRK	6.84e-03	18	130	2	IPR000998
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	6.84e-03	18	130	2	IPR008930
Domain	MAM_2	NRP2 PTPRK	6.84e-03	18	130	2	PS50060
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA1 CHRNA3	2.99e-05	9	102	3	M27597
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA1 CHRNA3	2.99e-05	9	102	3	MM15313
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA1 CHRNA3	5.82e-05	11	102	3	M883
Pathway	REACTOME_PRESYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA1 CHRNA3	7.72e-05	12	102	3	M48008
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA6 CHRNA1 CHRNA3	7.72e-05	12	102	3	MM15312
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA6 CHRNA1 CHRNA3	1.26e-04	14	102	3	M757
Pathway	REACTOME_ACETYLCHOLINE_BINDING_AND_DOWNSTREAM_EVENTS	CHRNA6 CHRNA1 CHRNA3	1.57e-04	15	102	3	MM14704
Pathway	REACTOME_PENTOSE_PHOSPHATE_PATHWAY	PRPS2 PRPS1L1 PRPS1	1.57e-04	15	102	3	M27682
Pathway	REACTOME_PENTOSE_PHOSPHATE_PATHWAY	PRPS2 PRPS1L1 PRPS1	1.57e-04	15	102	3	MM15404
Pubmed	Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms.	PRPS2 PRPS1L1 PRPS1	5.59e-08	3	134	3	1314091
Pubmed	The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity.	FCGR3A FCGR3B C4A C4B	1.02e-07	12	134	4	31801071
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CUL4B SET KIF23 LRWD1 CALR MATR3 INSR DHX15 NBAS PPP2R5D RRP12 ZNF566 MSL3 KIF14 PHF10 TOP2A AQR ANAPC4 TGS1	1.05e-07	1155	134	19	20360068
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A3 LRRC37A2 LRRC37A	2.23e-07	4	134	3	22419166
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF13B DIS3L NTNG1 DENND3 SACS DNAH17 LPGAT1 MACF1 ARHGAP28 MGA PUS7 SEC14L1	5.09e-07	493	134	12	15368895
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	SPEG DOCK9 RFC5 ME1 OPA1 GRID2IP RRP12 C4A C4B DNAI7 HYDIN ANAPC4	5.54e-07	497	134	12	36774506
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NRCAM SPEG DOCK9 CUL9 OPA1 MEGF8 TENM3 RRP12 MTMR3 MACF1 AQR	5.59e-07	407	134	11	12693553
Pubmed	The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.	SET CALR CUL9 CBX4 MIER1 PPP2R5D MSL3 MACF1 ANAPC4	1.61e-06	282	134	9	23667531
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	LRWD1 CALR MATR3 INSR RFC5 MYO5C DHX15 SACS RRP12 KIF14 MACF1 RP2 MGA VARS1 TOP2A AQR	2.25e-06	1024	134	16	24711643
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	LRRC37A3 PCLO OPA1 LRRC37A MGA AQR	3.44e-06	105	134	6	9628581
Pubmed	A Restricted Role for FcγR in the Regulation of Adaptive Immunity.	CSF1R FCGR3A FCGR3B	4.62e-06	9	134	3	29523656
Pubmed	Sources of energy for gating by neurotransmitters in acetylcholine receptor channels.	CHRNA6 CHRNA1 CHRNA3	4.62e-06	9	134	3	22647603
Pubmed	Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.	FOXN2 NRCAM INSR NTNG1 FOXJ3 NRP2 LRP5 SMO	6.27e-06	251	134	8	29031500
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A3 LRRC37A2 LRRC37A	6.58e-06	10	134	3	23064749
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CUL4B MATR3 CPD RFC5 OPA1 GLMN PPP2R5D SUGP1 VARS1 TOP2A AQR	1.18e-05	560	134	11	35241646
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	IFT57 CALR DUSP8 CPD ME1 OPA1 GLMN PPP2R5D MTMR14 PTPRK KLHL15 RRP12 VPS13A MTMR3 KIF14	1.36e-05	1049	134	15	27880917
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	1.47e-05	2	134	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	1.47e-05	2	134	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	1.47e-05	2	134	2	15998580
Pubmed	Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG.	FCGR3A FCGR3B	1.47e-05	2	134	2	2521732
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	1.47e-05	2	134	2	19062096
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	1.47e-05	2	134	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	1.47e-05	2	134	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	1.47e-05	2	134	2	17645767
Pubmed	Interaction of calreticulin with protein disulfide isomerase.	CALR PDIA2	1.47e-05	2	134	2	8537405
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	1.47e-05	2	134	2	12207352
Pubmed	Single-cell analyses identify dysfunctional CD16+ CD8 T cells in smokers.	FCGR3A FCGR3B	1.47e-05	2	134	2	33163982
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	1.47e-05	2	134	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	1.47e-05	2	134	2	22387014
Pubmed	Lack of Lrp5 Signaling in Osteoblasts Sensitizes Male Mice to Diet-Induced Disturbances in Glucose Metabolism.	INSR LRP5	1.47e-05	2	134	2	28938444
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	1.47e-05	2	134	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	1.47e-05	2	134	2	23918728
Pubmed	Association study of copy number variants in FCGR3A and FCGR3B gene with risk of ankylosing spondylitis in a Chinese population.	FCGR3A FCGR3B	1.47e-05	2	134	2	26494566
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	1.47e-05	2	134	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	1.47e-05	2	134	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	1.47e-05	2	134	2	4216347
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	1.47e-05	2	134	2	6950384
Pubmed	SIRT7 promotes the proliferation and migration of anaplastic thyroid cancer cells by regulating the desuccinylation of KIF23.	KIF23 SIRT7	1.47e-05	2	134	2	38360598
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	1.47e-05	2	134	2	8660986
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	1.47e-05	2	134	2	8428773
Pubmed	Impact of allele copy number of polymorphisms in FCGR3A and FCGR3B genes on susceptibility to ulcerative colitis.	FCGR3A FCGR3B	1.47e-05	2	134	2	23917248
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	1.47e-05	2	134	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	1.47e-05	2	134	2	21345967
Pubmed	Interaction of newly synthesized apolipoprotein B with calnexin and calreticulin requires glucose trimming in the endoplasmic reticulum.	CALR APOB	1.47e-05	2	134	2	10513896
Pubmed	Evidence for gene recombination in FCGR3 gene variants.	FCGR3A FCGR3B	1.47e-05	2	134	2	19320901
Pubmed	Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.	FCGR3A FCGR3B	1.47e-05	2	134	2	25966632
Pubmed	The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein.	FCGR3A FCGR3B	1.47e-05	2	134	2	2967436
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	1.47e-05	2	134	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	1.47e-05	2	134	2	2302180
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	1.47e-05	2	134	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	1.47e-05	2	134	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	1.47e-05	2	134	2	29080553
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	1.47e-05	2	134	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	1.47e-05	2	134	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	1.47e-05	2	134	2	17728371
Pubmed	Structure and organization of the C4 genes.	C4A C4B	1.47e-05	2	134	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	1.47e-05	2	134	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	1.47e-05	2	134	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	1.47e-05	2	134	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	1.47e-05	2	134	2	2387317
Pubmed	Calreticulin and Hsp90 stabilize the human insulin receptor and promote its mobility in the endoplasmic reticulum.	CALR INSR	1.47e-05	2	134	2	17563366
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	1.47e-05	2	134	2	16908004
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	1.47e-05	2	134	2	7365238
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	1.47e-05	2	134	2	7391573
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	1.47e-05	2	134	2	17971360
Pubmed	Low copy numbers of FCGR3A and FCGR3B associated with Chinese patients with SLE and AASV.	FCGR3A FCGR3B	1.47e-05	2	134	2	28355982
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	1.47e-05	2	134	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	1.47e-05	2	134	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	1.47e-05	2	134	2	6881182
Pubmed	Apolipoprotein B and angiotensin-converting enzyme polymorphisms and aerobic interval training: randomized controlled trial in coronary artery disease patients.	APOB ACE	1.47e-05	2	134	2	29846435
Pubmed	The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions.	FCGR3A FCGR3B	1.47e-05	2	134	2	7836402
Pubmed	Identification of an ADAM17 cleavage region in human CD16 (FcγRIII) and the engineering of a non-cleavable version of the receptor in NK cells.	FCGR3A FCGR3B	1.47e-05	2	134	2	25816339
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	1.47e-05	2	134	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	1.47e-05	2	134	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	1.47e-05	2	134	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	1.47e-05	2	134	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	1.47e-05	2	134	2	28873507
Pubmed	Splicing quality control mediated by DHX15 and its G-patch activator SUGP1.	DHX15 SUGP1	1.47e-05	2	134	2	37805921
Pubmed	Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement.	C4A C4B	1.47e-05	2	134	2	276882
Pubmed	Amino acid sequence of a polymorphic segment from fragment C4d of human complement component C4.	C4A C4B	1.47e-05	2	134	2	6832377
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	1.47e-05	2	134	2	3794341
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	1.47e-05	2	134	2	22785613
Pubmed	The loss of the CD16 B73.1/Leu11c epitope occurring in some primary immunodeficiency diseases is not associated with the FcgammaRIIIa-48L/R/H polymorphism.	FCGR3A FCGR3B	1.47e-05	2	134	2	20664961
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	1.47e-05	2	134	2	32691186
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	1.47e-05	2	134	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	1.47e-05	2	134	2	3902619
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	1.47e-05	2	134	2	7373044
Pubmed	FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene.	FCGR3A FCGR3B	1.47e-05	2	134	2	34108956
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	1.47e-05	2	134	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	1.47e-05	2	134	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	1.47e-05	2	134	2	16098595
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	1.47e-05	2	134	2	15787745
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	1.47e-05	2	134	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	1.47e-05	2	134	2	6559257
Pubmed	[Increased activity of PRPP synthetase].	PRPS2 PRPS1	1.47e-05	2	134	2	18409517
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	1.47e-05	2	134	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	1.47e-05	2	134	2	20506482
Pubmed	The human natural killer cytotoxic cell line NK-92, once armed with a murine CD16 receptor, represents a convenient cellular tool for the screening of mouse mAbs according to their ADCC potential.	FCGR3A FCGR3B	1.47e-05	2	134	2	23770975
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	1.47e-05	2	134	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	1.47e-05	2	134	2	26800705
Interaction	CBX3 interactions	CUL4B SETD1A SET KIF23 LRWD1 CALR DUSP8 SIRT7 ZNF566 SUGP1 KIF14 MACF1 MGA PHF10 TOP2A PUS7	4.68e-06	646	131	16	int:CBX3
Cytoband	1q23-q25	PAPPA2 PIGC	5.05e-05	4	134	2	1q23-q25
GeneFamily	Immunoglobulin like domain containing	NRCAM LAIR1 CSF1R PTPRK FCGR3A FCGR3B IGSF3	5.77e-05	193	92	7	594
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA6 CHRNA1 CHRNA3	6.81e-05	16	92	3	173
GeneFamily	Fibronectin type III domain containing	NRCAM INSR CNTN6 LIFR CSF2RB PTPRK	1.66e-04	160	92	6	555
GeneFamily	Cullins	CUL4B CUL9	7.03e-04	8	92	2	1032
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	INSR LAIR1 ACE LIFR CSF1R CSF2RB FCGR3A FCGR3B	8.95e-04	394	92	8	471
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	9.01e-04	9	92	2	1234
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF13B KIF23 KIF14	1.65e-03	46	92	3	622
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR14 MTMR3	2.58e-03	15	92	2	903
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	KIF23 DOCK9 FOXJ3 RGS7 OPA1 DHX15 NBAS PTPRK SACS VPS13A MTMR3 KIF14 MACF1 TOP2A AQR SEC14L1	6.70e-06	856	132	16	M4500
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK9 CPD ACE DENND3 LIFR PTPRK LRP5	1.83e-06	192	133	7	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CDK20 LRRC37A3 LRRC37A DNAI7 SPAG17 HYDIN TOP2A	2.17e-06	197	133	7	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Mesothelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	NTNG1 KERA TENM3 PDIA2 ARHGAP28 C4A C4B	2.32e-06	199	133	7	ca970114b5aef4518ce580897a62ac88688b2671
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular\|TCGA-Stomach / Sample_Type by Project: Shred V9	KIF23 TMEM260 RRP12 KIF14 VARS1 TOP2A	3.72e-06	138	133	6	93497c0a5d5e54006653b2dedc7a7041e1a613e6
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 ADTRP CSF1R FCGR3B C4A TOP2A	6.49e-06	152	133	6	bfc7ef4ee26165d18ac4f475a9519e8d52453ba2
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 CLCA4 LAIR1 CSF1R CSF2RB FCGR3B	7.81e-06	157	133	6	7fdc0094dd5729990a91a30c1982a14c74650b52
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 CLCA4 LAIR1 CSF1R CSF2RB FCGR3B	7.81e-06	157	133	6	c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 CLCA4 LAIR1 CSF1R CSF2RB FCGR3B	7.81e-06	157	133	6	6b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCell	facs-Spleen-nan-3m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE CSF1R CSF2RB FCGR3A FCGR3B ARHGAP28	9.01e-06	161	133	6	45591addc765760db6029ac19e80573373d1d917
ToppCell	facs-Spleen-nan-3m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE CSF1R CSF2RB FCGR3A FCGR3B ARHGAP28	9.01e-06	161	133	6	8741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCell	facs-Spleen-nan-3m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE CSF1R CSF2RB FCGR3A FCGR3B ARHGAP28	9.01e-06	161	133	6	9cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 ACE CSF1R CSF2RB FCGR3A FCGR3B	1.19e-05	169	133	6	2d3618f78484bd3508b7bdae3a0d0183cdae5057
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPPA2 LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.19e-05	169	133	6	0f5e737b265ba333275a0cd289dab029a1542075
ToppCell	facs-Liver-Non-hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 ACE CSF1R CSF2RB FCGR3A FCGR3B	1.23e-05	170	133	6	f08aa6168ff0c20b2083dbf588dd3294e3d9580e
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAND2 NLRP1 CSF1R MEGF8 SMO SGSM3	1.40e-05	174	133	6	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	LRRC37A3 LAIR1 LRRC37A CSF1R CSF2RB LRP5	1.45e-05	175	133	6	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK9 INSR DENND3 LIFR ADAMTS7 SEC14L1	1.70e-05	180	133	6	efc4c5a4dea456527526bbfd88cf70d803893671
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	MATR3 VPS13A OSBPL10 KIF14 MGA AQR	1.92e-05	184	133	6	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	SETD1A MATR3 VPS13A OSBPL10 KIF14 TOP2A	1.92e-05	184	133	6	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	SETD1A MATR3 VPS13A OSBPL10 KIF14 TOP2A	1.92e-05	184	133	6	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	INSR DENND3 NRP2 PRDM1 PHF10 SEC14L1	1.98e-05	185	133	6	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-C\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CHRNA6 LRRC37A2 LAIR1 SPATA20 CSF1R FCGR3A	2.30e-05	190	133	6	259085b9731902ca0956233afafe1db6fc98e851
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	CUL4B FOXN2 CPD PTPRK MGA AQR	2.52e-05	193	133	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	INSR DENND3 NRP2 PRDM1 PHF10 SEC14L1	2.52e-05	193	133	6	479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK9 ACE DENND3 LIFR LRP5 SEC14L1	2.59e-05	194	133	6	f159ef8541d75a4e98468947f231bb463bec922c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_basal-Dividing_Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	APOB MYO5C KIF14 MMP15 ZNF471 TOP2A	2.59e-05	194	133	6	d790cfff3664e46fe2fd2f6b0c26896799927845
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK9 INSR DENND3 NRP2 MACF1 SEC14L1	2.67e-05	195	133	6	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	Bronchial_Biopsy-Immune-Luminal_Macrophages\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	LAIR1 ADTRP ACE ME1 NRP2 FCGR3A	2.67e-05	195	133	6	6800c17026ec6c56132bf4664b8fcd74d7836579
ToppCell	facs-Aorta-Heart-3m-Endothelial-aorta_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSR NRP2 PRDM1 LIFR ADAMTS7 MACF1	2.67e-05	195	133	6	3969b8d5fcec8ef1831531a781f7bbcebab5a4ba
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	DOCK9 INSR NRP2 LIFR OSBPL10 SEC14L1	2.74e-05	196	133	6	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	severe-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DIS3L DOCK9 DENND3 FAR2 FCGR3B TOP2A	2.82e-05	197	133	6	70704b149b2820b8601d2495b7cd9cbe91eda262
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NRCAM NTNG1 LIFR TENM3 MACF1 SMO	2.99e-05	199	133	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Control-Control-Myeloid-Neutrophil\|Control / Disease, condition lineage and cell class	NLRP1 CSF2RB FCGR3A FCGR3B MTMR3 SEC14L1	3.07e-05	200	133	6	95c41f147a1594d49e73cb56d86d301c3115ce20
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PCLO HLCS CPD MYO5C PTPRK LRP5	3.07e-05	200	133	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUL9 GLMN C4A SMO C4B	3.42e-05	123	133	5	a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KIF23 LAIR1 CSF1R FCGR3B PUS7	7.73e-05	146	133	5	26493014daa432db721613ef480d133f3da9eb58
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 ADTRP CSF1R FCGR3B C4A	8.25e-05	148	133	5	7c7c87b57aa16f8b91698489df39ace5a3a53df8
ToppCell	facs-Trachea-nan-3m-Myeloid-granulocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF23 PRPS1L1 CSF2RB FCGR3A FCGR3B	8.51e-05	149	133	5	9c4837aa63e46382ff45a41c72beb5722b3ada19
ToppCell	droplet-Fat-SCAT-30m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 NEK3 CSF1R KIF14 RP2	9.64e-05	153	133	5	2731c3d4ac40ecc22108f8f3f45a069077159125
ToppCell	facs-Heart-RV-24m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R FCGR3A FCGR3B KIF14	9.94e-05	154	133	5	709e7eedec11e675c6bbd55940f91dea5f715f4c
ToppCell	facs-Heart-RV-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R FCGR3A FCGR3B KIF14	9.94e-05	154	133	5	8c65d4ea787a75f20448b11beea571d7ec684721
ToppCell	facs-Heart-RV-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R FCGR3A FCGR3B KIF14	9.94e-05	154	133	5	60e7c03d91ea87eb6226a744633cbe6efa9a9928
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_ALM_Npsr1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PAPPA2 CHRNA6 NTNG1 KIF14	1.02e-04	81	133	4	5d9b08bc1ae6ecb894c88c9784fdc4203682d087
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 LAIR1 CSF1R FCGR3B TOP2A	1.03e-04	155	133	5	0e24e767a3895d31d34cabeaca0354aadae34e44
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 LAIR1 CSF1R FCGR3B TOP2A	1.03e-04	155	133	5	f3489a548a2c0cc2d9117ff85865c6089ea0835d
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	WDR31 TMEM260 NEK3 PTPRK TOP2A	1.06e-04	156	133	5	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	WDR31 TMEM260 NEK3 PTPRK TOP2A	1.06e-04	156	133	5	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CHRNA3 GUCY1B2 ADAMTS7 DNAH17	1.07e-04	82	133	4	73349906bcc8d1a40dc03df7a490a963e85564f2
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CHRNA3 GUCY1B2 ADAMTS7 DNAH17	1.07e-04	82	133	4	15bc417aaace2b1d680904a622fe76e95083c9ff
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	CHRNA3 GUCY1B2 ADAMTS7 DNAH17	1.07e-04	82	133	4	697e1da3095c8483b8181b290fa5417bdc9cee54
ToppCell	droplet-Kidney-nan-18m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.09e-04	157	133	5	eb64a4e89843895d16015c7d51805f164ed7ea5b
ToppCell	droplet-Bladder-Unstain-18m-Hematologic-leukocyte\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.16e-04	159	133	5	89b5e895e95cdd654edd471bde9b6887939b3503
ToppCell	droplet-Bladder-Unstain-18m-Hematologic\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.16e-04	159	133	5	a80b4637a74bcc6f213d584aba2c727a983eedb3
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP1 ACE CSF1R CSF2RB FCGR3B	1.16e-04	159	133	5	cdbccb83af6220bab300dfe56443ff69f6e2043a
ToppCell	facs-MAT-Fat-18m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.19e-04	160	133	5	bd5fa7959bfe81011b8d798535b73ea1eee008b3
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACE TMEM260 CSF1R FCGR3A LRP5	1.23e-04	161	133	5	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GLMN HIBCH VPS13A PUS7 PRPS1	1.23e-04	161	133	5	d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.23e-04	161	133	5	787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.23e-04	161	133	5	3db97af49520dc8cbafb4454d8afd9d588160e89
ToppCell	droplet-Mammary_Gland-nan-21m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.23e-04	161	133	5	f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCell	Myeloid\|World / shred on cell class and cell subclass (v4)	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.23e-04	161	133	5	aee407d3739dba2d5216dcdb1579e7e4f483123d
ToppCell	droplet-Mammary_Gland-nan-18m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.26e-04	162	133	5	59147406c28b7cdf43a1815f99c15c2bd6ae8fa3
ToppCell	droplet-Mammary_Gland-nan-18m-Myeloid\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.26e-04	162	133	5	8e0bcc23c3086fc4b0c9dbeec13a7edaf6b83750
ToppCell	droplet-Mammary_Gland-nan-18m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.26e-04	162	133	5	736fdcbd0f7d50fc297f13d36ab4c0dc82ad509c
ToppCell	facs-Heart-RA-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 ADTRP CSF1R FCGR3A FCGR3B	1.30e-04	163	133	5	da7ab9582e8070b07ca628a6394c86684d37d6ef
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.34e-04	164	133	5	8d089844896e84935eab705ebe54f125c4b6d9ca
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.34e-04	164	133	5	939d4e3911fce185b986639c815de0a0389f6cfd
ToppCell	droplet-Kidney-nan-24m-Myeloid-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.34e-04	164	133	5	d57faa4fce1f1e9a92aaf5cb920af99323252e4b
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.34e-04	164	133	5	3281f2452cc6b11f3e030a3942002b9457dde6fe
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.34e-04	164	133	5	17fb1421476ba44999b1165f2576514f74c1f882
ToppCell	droplet-Kidney-nan-24m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.34e-04	164	133	5	d0b6c29e61d15f4dbe4c1f6e5ed3e10f41f820ab
ToppCell	droplet-Kidney-nan-24m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.34e-04	164	133	5	718cc64b7ef7d03d095be4b2b54c449154da568c
ToppCell	facs-Pancreas-Endocrine-3m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.37e-04	165	133	5	2e9e703c3f89784a47ed40f799d2aa86eba6cc9a
ToppCell	facs-Pancreas-Endocrine-3m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.37e-04	165	133	5	4d51eb992670bce164eea29b540877b4d567953c
ToppCell	facs-Kidney-nan-24m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.37e-04	165	133	5	a359dda24c2c10b7b8df902a7c4c2ebf27b041f3
ToppCell	facs-Kidney-nan-24m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.37e-04	165	133	5	1d5880aa49e6e6e95bde14a40fbe6e40b71c6d22
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC38A4 APOB ME1 PCYT2 HACL1	1.37e-04	165	133	5	d449a568664a81d9b5538e8f409301448a32ac37
ToppCell	facs-Kidney-nan-24m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.37e-04	165	133	5	cdc09cbfd6eaeb8e436d83bbca7146bde3b3f01e
ToppCell	facs-Lung-nan-3m-Myeloid\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.37e-04	165	133	5	720649f330382ea2a68c64a5344160a048afb8f1
ToppCell	facs-Pancreas-Endocrine-3m-Hematologic-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.37e-04	165	133	5	8715ea74d02e9b7cd05fa1b4896b353078544678
ToppCell	facs-MAT-Fat-18m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.41e-04	166	133	5	9116be2805c34881debb999d8417e43832fcf2f2
ToppCell	facs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLCS NADSYN1 RRP12 RP2 DNAI7	1.41e-04	166	133	5	5c132f505dc5f699c87913f140344fc9f8e7e0f5
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP1 CSF1R CSF2RB FCGR3B RP2	1.41e-04	166	133	5	82fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCell	facs-MAT-Fat-18m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.41e-04	166	133	5	5c2667da79935f3d4b1edbfe7a10e7dbc2fa3ad0
ToppCell	367C-Myeloid-Monocyte-CD16+_Monocyte\|367C / Donor, Lineage, Cell class and subclass (all cells)	LRRC37A CSF2RB MTMR14 FCGR3B CCL16	1.41e-04	166	133	5	430d604f5bef9fae20dc81492e6695616f6701a3
ToppCell	facs-Heart-RA-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.41e-04	166	133	5	e868e90b5272da6ccfc1c371e1b1aac1d63c5139
ToppCell	facs-Heart-LA-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3B C4B	1.41e-04	166	133	5	2c931d593e189127c31adaf36a3df81d8287bb53
ToppCell	droplet-Bladder-nan-24m-Hematologic\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.41e-04	166	133	5	9951ed7b5492b949b8db49969308f919d89468e5
ToppCell	facs-Heart-LA-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3B C4B	1.41e-04	166	133	5	9e7a9cb7beeb7015fcaa476a4902883dee99e8c0
ToppCell	facs-Heart-RA-24m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.41e-04	166	133	5	af30d3fa9380056be17b0dc720c8be09418b5529
ToppCell	facs-Heart-LA-24m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3B C4B	1.41e-04	166	133	5	2a3c396deb068066b8c2f85ddd2fa52629776bcd
ToppCell	facs-Heart-RA-24m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.41e-04	166	133	5	fb3daa5e5a6d9ecf52ef2e019258e84761e87b65
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLRP1 CSF1R CSF2RB FCGR3B RP2	1.41e-04	166	133	5	0d03926452414f232c77fd15d5f48d148f9fca3b
ToppCell	droplet-Bladder-nan-24m-Hematologic-leukocyte\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.41e-04	166	133	5	eadc88669710895f43544d81e08c97248488f19b
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPD PRPS1L1 NEK3 FCGR3A SEC14L1	1.45e-04	167	133	5	528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.45e-04	167	133	5	7f9eedf68a800159c5642e04dd9569ae58109bd5
ToppCell	droplet-Liver-LIVER-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 CSF1R CSF2RB FCGR3A FCGR3B	1.45e-04	167	133	5	a038c522e4783cb62802f613d00bd5f3e3797199
ToppCell	facs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPD PRPS1L1 NEK3 FCGR3A SEC14L1	1.45e-04	167	133	5	a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCell	droplet-Kidney-nan-24m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAIR1 ACE CSF1R CSF2RB FCGR3A	1.45e-04	167	133	5	2ee1660be117e20f24557522345572d11cbee813
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	CAND2 SPEG MATR3 SMO MPI	1.45e-04	167	133	5	c4e321bb87512ea839f324c92c0f1afea891483f
Drug	Gliquidone [33342-05-1]; Down 200; 7.6uM; HL60; HT_HG-U133A	SETD1A BIN1 NRCAM PCLO DUSP8 NLRP1 MTMR3 SUGP1 SGSM3 SEC14L1	2.34e-07	197	132	10	3126_DN
Drug	Diflorasone Diacetate [33564-31-7]; Up 200; 8uM; PC3; HT_HG-U133A	PAPPA2 FOXN2 INSR LAIR1 HLCS NTNG1 NLRP1 NRP2 RRP12 SMO	2.34e-07	197	132	10	4077_UP
Drug	fenoxycarb	CHRNA6 HLCS CHRNA1 CHRNA3 PRDM1 SUGP1 LRP5	4.19e-07	80	132	7	CID000051605
Drug	C-toxiferine-I	CHRNA6 CALR CHRNA1 CHRNA3	7.41e-07	13	132	4	CID005089093
Drug	Loperamide hydrochloride [34552-83-5]; Up 200; 7.8uM; PC3; HT_HG-U133A	SETD1A CHRNA6 DOCK9 INSR LAIR1 KERA DENND3 RRP12 DNAI7	1.63e-06	189	132	9	4672_UP
Drug	benzoquinonium	CHRNA6 CHRNA1 CHRNA3 RP2	1.86e-06	16	132	4	CID000009393
Drug	Pronethalol hydrochloride [51-02-5]; Up 200; 15uM; HL60; HT_HG-U133A	PAPPA2 BIN1 HLCS NLRP1 ADTRP CHRNA3 MYO5C TENM3 SEC14L1	2.39e-06	198	132	9	2902_UP
Drug	Niridazole [61-57-4]; Up 200; 18.6uM; MCF7; HT_HG-U133A	DOCK9 PCLO LAIR1 HLCS ADTRP LCT CHRNA3 DENND3 PRDM1	2.39e-06	198	132	9	5682_UP
Drug	Cefsulodin sodium salt [52152-93-9]; Up 200; 7.2uM; PC3; HT_HG-U133A	CDK20 PAPPA2 HLCS NTNG1 NRP2 CSF1R RRP12 SUGP1 CCL16	2.50e-06	199	132	9	4067_UP
Drug	methyl iodoacetate	PRPS2 PRPS1L1 PRPS1	3.76e-06	6	132	3	CID006429536
Drug	APP-MP	PRPS2 PRPS1L1 PRPS1	3.76e-06	6	132	3	CID003081102
Drug	pyrimidine-5-nucleotide	PRPS2 PRPS1L1 PRPS1	3.76e-06	6	132	3	CID000440040
Drug	Sesquimustard	NLRP1 CPD OPA1 MMP15 MPI	4.90e-06	43	132	5	CID000019092
Drug	AC1L1GWH	LCT FCGR3A FCGR3B	1.56e-05	9	132	3	CID000003872
Drug	radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; HL60; HT_HG-U133A	SETD1A FOXN2 CBX4 ADTRP MAP3K1 SGSM3 PUS7 TGS1	1.80e-05	194	132	8	6178_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; PC3; HT_HG-U133A	PAPPA2 NLRP1 NRP2 CSF1R CSF2RB RRP12 SUGP1 SMO	1.87e-05	195	132	8	4070_UP
Drug	(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; MCF7; HT_HG-U133A	KIF13B PCLO CUL9 PIGC CSF2RB MSL3 SUGP1 MMP15	1.94e-05	196	132	8	3889_UP
Drug	echothiophate	CHRNA6 CHRNA1 CHRNA3 PCYT2	1.98e-05	28	132	4	CID000010547
Drug	Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A	KIF13B BIN1 PCLO NLRP1 CBX4 PRDM1 MTMR3 SEC14L1	2.01e-05	197	132	8	3122_DN
Drug	Cefotiam hydrochloride; Down 200; 7.2uM; MCF7; HT_HG-U133A	CDK20 CUL9 OPA1 NEK3 MSL3 SUGP1 SGSM3 AQR	2.01e-05	197	132	8	5361_DN
Drug	SR-95639A [115767-94-7]; Up 200; 10uM; PC3; HT_HG-U133A	PAPPA2 CHRNA6 LAIR1 NTNG1 NLRP1 NEK3 CSF1R DNAI7	2.08e-05	198	132	8	6632_UP
Drug	Reserpine [50-55-5]; Up 200; 6.6uM; MCF7; HT_HG-U133A	CHRNA6 PCLO NTNG1 CSF1R ADAMTS7 DNAH17 SUGP1 DNAI7	2.08e-05	198	132	8	3341_UP
Drug	sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A	HLCS CHRNA3 DENND3 NRP2 RRP12 DNAH17 MTMR3 SMO	2.16e-05	199	132	8	309_UP
Drug	Nifurtimox [23256-30-6]; Up 200; 14uM; MCF7; HT_HG-U133A	BIN1 DOCK9 PCLO DUSP8 HLCS CBX4 PIGC SUGP1	2.24e-05	200	132	8	4953_UP
Drug	Dithiol	CALR NLRP1 SPATA20 ME1 PCYT2 PDIA2	2.58e-05	100	132	6	CID000010334
Drug	methylenedioxydimethylamphetamine	CHRNA6 NLRP1 CHRNA1 CHRNA3	2.63e-05	30	132	4	CID000551630
Drug	Dns-C6-Cho	CHRNA6 CHRNA1 CHRNA3	3.04e-05	11	132	3	CID000124728
Drug	AC1L9NC9	CHRNA6 CHRNA1 CHRNA3	3.04e-05	11	132	3	CID000449642
Drug	dihydronereistoxin	CHRNA6 CHRNA1 CHRNA3	3.04e-05	11	132	3	CID000121232
Drug	LJP 1082	CHRNA6 CHRNA1 CHRNA3	3.04e-05	11	132	3	CID003037609
Drug	bipinnatin-B	CHRNA6 CHRNA1 CHRNA3	3.04e-05	11	132	3	CID000127363
Drug	tropicamide	CHRNA6 CALR CHRNA1 CHRNA3	3.42e-05	32	132	4	CID000005593
Drug	decamethonium	CHRNA6 CHRNA1 CHRNA3 RP2	3.88e-05	33	132	4	CID000002968
Drug	AC1L9P8C	CHRNA6 CHRNA1 CHRNA3	4.03e-05	12	132	3	CID000450864
Drug	Dhga	PRPS2 PRPS1L1 PRPS1	4.03e-05	12	132	3	CID000467478
Drug	SureCN373116	CHRNA6 CHRNA1 CHRNA3	4.03e-05	12	132	3	CID010085732
Drug	gallamine	CHRNA6 CHRNA1 CHRNA3 TGS1	4.92e-05	35	132	4	CID000003450
Drug	AC1Q6T3B	PRPS2 PRPS1L1 PCYT2 PRPS1	4.92e-05	35	132	4	CID000000293
Drug	2,6,6-tetramethylpiperidine	PRPS2 PRPS1L1 PRPS1	5.22e-05	13	132	3	CID000013035
Drug	nereistoxin	CHRNA6 CHRNA1 CHRNA3	5.22e-05	13	132	3	CID000015401
Drug	1-acetyl-4-methylpiperazine methiodide	CHRNA6 CHRNA1 CHRNA3	5.22e-05	13	132	3	CID004392675
Drug	bipinnatin-A	CHRNA6 CHRNA1 CHRNA3	5.22e-05	13	132	3	CID000196603
Drug	NSC-614841	FCGR3A FCGR3B C4A	5.22e-05	13	132	3	CID000357070
Drug	bipinnatin-C	CHRNA6 CHRNA1 CHRNA3	5.22e-05	13	132	3	CID000129977
Drug	2,6-diaminonebularine	PRPS2 PRPS1L1 PRPS1	5.22e-05	13	132	3	CID000072200
Drug	HPMPApp	PRPS2 PRPS1L1 PRPS1	6.62e-05	14	132	3	CID000506018
Drug	2,3-dichlorooctafluorobutane	CHRNA6 CHRNA1 CHRNA3	6.62e-05	14	132	3	CID000078982
Drug	LNF 209	CHRNA6 CHRNA1 CHRNA3	6.62e-05	14	132	3	CID000132666
Drug	Laurdan	CHRNA6 APOB CHRNA1 CHRNA3	6.84e-05	38	132	4	CID000104983
Drug	anatoxin-a hydrochloride	CHRNA6 CHRNA1 CHRNA3	8.24e-05	15	132	3	CID000135265
Drug	SAD-128	CHRNA6 CHRNA1 CHRNA3	8.24e-05	15	132	3	CID000162008
Drug	N-methylcytisine	CHRNA6 CHRNA1 CHRNA3	8.24e-05	15	132	3	CID000234566
Drug	aa373	CHRNA6 CHRNA1 CHRNA3	8.24e-05	15	132	3	CID000191672
Drug	(-)-pictamine	CHRNA6 CHRNA1 CHRNA3	8.24e-05	15	132	3	CID006918623
Drug	(-)-lepadin B	CHRNA6 CHRNA1 CHRNA3	8.24e-05	15	132	3	CID006918624
Drug	UB-165	CHRNA6 CHRNA1 CHRNA3	8.24e-05	15	132	3	CID004694339
Drug	orotic acid	PRPS2 APOB LCT PRPS1L1 SMO PRPS1	8.65e-05	124	132	6	CID000000967
Drug	AC1L1BQX	CHRNA6 CHRNA1 CHRNA3 SPAG17 MPI	9.70e-05	79	132	5	CID000001565
Drug	diethyl ethylphosphonate	NLRP1 ACE	9.97e-05	3	132	2	CID000006534
Drug	2-aminothiophenol	C4A C4B	9.97e-05	3	132	2	ctd:C005464
Drug	DPEC	FCGR3A FCGR3B	9.97e-05	3	132	2	CID000129670
Drug	3-(trifluoromethyl)-3-(m-iodophenyl)diazirine	CHRNA6 CHRNA1 CHRNA3	1.01e-04	16	132	3	CID000123866
Drug	AC1L2SVN	CHRNA6 CHRNA1 CHRNA3	1.01e-04	16	132	3	CID000127922
Drug	AC1N19IL	CPD ACE C4A	1.01e-04	16	132	3	CID004001756
Drug	PNU-282,987	CHRNA6 CHRNA1 CHRNA3	1.01e-04	16	132	3	CID004655349
Drug	AC1L2I23	PRPS2 PRPS1L1 PRPS1	1.01e-04	16	132	3	CID000047419
Drug	pyrophosphate	PRPS2 IFT57 HLCS RFC5 MYO5C PRPS1L1 NADSYN1 GUCY1B2 PCYT2 VARS1 ANAPC4 MPI PRPS1	1.13e-04	654	132	13	CID000001023
Drug	Nsc36388	CHRNA6 CHRNA1 CHRNA3	1.22e-04	17	132	3	CID000014954
Drug	dihydro-beta-erythroidine	CHRNA6 NLRP1 CHRNA1 CHRNA3	1.22e-04	44	132	4	CID000031762
Drug	radicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A	PAPPA2 BIN1 ME1 CSF1R ADAMTS7 RRP12 SUGP1	1.32e-04	192	132	7	5216_UP
Drug	ICI 182,780; Down 200; 0.01uM; PC3; HT_HG-U133A	SETD1A HLCS RGS7 RRP12 MTMR3 SUGP1 SMO	1.32e-04	192	132	7	4462_DN
Drug	Propafenone hydrochloride [34183-22-7]; Up 200; 10.6uM; MCF7; HT_HG-U133A	CUL4B KIF13B CHRNA6 FOXN2 BIN1 NTNG1 CUL9	1.36e-04	193	132	7	5437_UP
Drug	Nadolol [42200-33-9]; Up 200; 13uM; PC3; HT_HG-U133A	CDK20 CHRNA6 DOCK9 ACE NRP2 MMP15 ZNF471	1.41e-04	194	132	7	4021_UP
Drug	Pentamidine isethionate [140-64-7]; Up 200; 6.8uM; PC3; HT_HG-U133A	CDK20 CHRNA6 NLRP1 PRDM1 DNAH17 ARHGAP28 IGSF3	1.41e-04	194	132	7	4573_UP
Drug	Quinethazone [73-49-4]; Down 200; 13.8uM; PC3; HT_HG-U133A	FOXN2 DOCK9 HLCS CBX4 MSL3 SUGP1 ARHGAP28	1.41e-04	194	132	7	4529_DN
Drug	radicicol; Down 200; 0.1uM; PC3; HT_HG-U133A	FOXN2 HLCS NRP2 PRDM1 MEGF8 SUGP1 TGS1	1.41e-04	194	132	7	5952_DN
Drug	Hesperidin [520-26-3]; Up 200; 6.6uM; MCF7; HT_HG-U133A	PCLO CSF1R PIGC RRP12 MSL3 SUGP1 MMP15	1.45e-04	195	132	7	5313_UP
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A	HLCS CPD CBX4 ADTRP NRP2 LIFR MSL3	1.45e-04	195	132	7	3778_DN
Drug	Trifluridine [70-00-8]; Down 200; 13.6uM; MCF7; HT_HG-U133A	CDK20 KIF23 HLCS CBX4 KIF14 MMP15 TOP2A	1.45e-04	195	132	7	3559_DN
Drug	Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; MCF7; HT_HG-U133A	CDK20 KIF13B FOXJ3 MAP3K1 SUGP1 SGSM3 SEC14L1	1.45e-04	195	132	7	3459_DN
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	PAPPA2 DUSP8 SPATA20 FOXJ3 MAP3K1 LRP5 SEC14L1	1.45e-04	195	132	7	6163_DN
Drug	2-propylpentanoic acid; Down 200; 1000uM; PC3; HT_HG-U133A	SETD1A CHRNA6 HLCS SUGP1 ARHGAP28 SMO SGSM3	1.45e-04	195	132	7	4433_DN
Drug	AC1L1AO2	PRPS2 PRPS1L1 PRPS1	1.46e-04	18	132	3	CID000001073
Drug	AC1O8PVM	CHRNA6 CHRNA1 CHRNA3	1.46e-04	18	132	3	CID000004989
Drug	ABT-594	CHRNA6 CHRNA1 CHRNA3	1.46e-04	18	132	3	CID003075702
Drug	AC1LCVGE	CHRNA6 CHRNA1 CHRNA3	1.46e-04	18	132	3	CID000656712
Drug	benzetimide	CHRNA6 CHRNA1 CHRNA3	1.46e-04	18	132	3	CID000021846
Drug	haloperidol; Up 200; 10uM; PC3; HT_HG-U133A	DOCK9 NTNG1 CHRNA1 CHRNA3 DENND3 MAP3K1 LIFR	1.50e-04	196	132	7	4468_UP
Drug	PF-00562151-00 [351320-12-2]; Down 200; 10uM; PC3; HT_HG-U133A	CDK20 SETD1A FOXJ3 NRP2 NEK3 SUGP1 SGSM3	1.50e-04	196	132	7	6863_DN
Drug	N-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; HL60; HT_HG-U133A	BIN1 NRCAM PCLO NLRP1 OPA1 MYO5C SUGP1	1.50e-04	196	132	7	3085_DN
Drug	Amyleine hydrochloride [532-59-2]; Up 200; 14.8uM; PC3; HT_HG-U133A	PAPPA2 CHRNA6 INSR KERA CSF1R RRP12 MMP15	1.50e-04	196	132	7	4089_UP
Drug	Pheniramine maleate [132-20-7]; Up 200; 11.2uM; PC3; HT_HG-U133A	INSR HLCS CHRNA3 NRP2 ARHGAP28 SGSM3 MMP15	1.55e-04	197	132	7	4012_UP
Drug	Clemastine fumarate [14976-57-9]; Down 200; 8.6uM; HL60; HT_HG-U133A	PAPPA2 INSR MEGF8 SUGP1 LRP5 SGSM3 TGS1	1.55e-04	197	132	7	2412_DN
Drug	Acetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; PC3; HT_HG-U133A	CHRNA6 HLCS ACE NRP2 NEK3 CSF1R SUGP1	1.55e-04	197	132	7	2061_UP
Drug	Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A	SETD1A FOXN2 BIN1 LAIR1 CHRNA3 VPS13A MSL3	1.55e-04	197	132	7	3554_UP
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A	CDK20 SETD1A FOXN2 MAP3K1 DNAH17 SUGP1 MMP15	1.55e-04	197	132	7	4371_DN
Drug	Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; PC3; HT_HG-U133A	KIF13B BIN1 DUSP8 CBX4 DENND3 SUGP1 SGSM3	1.55e-04	197	132	7	6611_DN
Drug	Dantrolene sodium salt [14663-23-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	BIN1 DOCK9 PCLO KERA NRP2 CSF2RB MEGF8	1.55e-04	197	132	7	3978_UP
Drug	Levopropoxyphene napsylate [5714-90-9]; Down 200; 7.4uM; MCF7; HT_HG-U133A	CDK20 ADTRP PPP2R5D VPS13A MSL3 SUGP1 SGSM3	1.55e-04	197	132	7	5503_DN
Drug	Lymecycline [992-21-2]; Up 200; 6.6uM; PC3; HT_HG-U133A	FOXN2 NRCAM DUSP8 ADTRP NEK3 CSF1R TGS1	1.59e-04	198	132	7	7291_UP
Disease	level of low affinity immunoglobulin gamma Fc region receptor III-A in blood serum	FCGR3A FCGR3B	1.93e-05	2	130	2	OBA_2040305
Disease	Intellectual Disability	SETD1A SET RGS7 PPP2R5D SACS KLHL15 MSL3 PCYT2 MACF1 PUS7	3.04e-05	447	130	10	C3714756
Disease	Autosomal Recessive Centronuclear Myopathy	BIN1 SPEG MTMR14	3.66e-05	15	130	3	C3645536
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA6 CHRNA1 CHRNA3	4.49e-05	16	130	3	DOID:3635 (implicated_via_orthology)
Disease	systemic lupus erythematosus	PRPS2 RFC5 CNTN6 MYO5C PRDM1 GLMN NADSYN1 HIBCH FCGR3A FCGR3B SMO C4B PUS7	5.44e-05	799	130	13	MONDO_0007915
Disease	Lupus Vasculitis, Central Nervous System	FCGR3A FCGR3B	5.76e-05	3	130	2	C0752332
Disease	Lupus Meningoencephalitis	FCGR3A FCGR3B	5.76e-05	3	130	2	C0752334
Disease	Neuropsychiatric Systemic Lupus Erythematosus	FCGR3A FCGR3B	5.76e-05	3	130	2	C0752335
Disease	Myopathy, Centronuclear, Autosomal Recessive	BIN1 SPEG	1.15e-04	4	130	2	C0410204
Disease	Centronuclear myopathy	BIN1 MTMR14	1.15e-04	4	130	2	cv:C0175709
Disease	hepatocellular carcinoma (is_implicated_in)	CALR CBX4 ACE PRDM1 CSF1R SMO	1.56e-04	181	130	6	DOID:684 (is_implicated_in)
Disease	Lupus Erythematosus, Systemic	PRDM1 FCGR3B C4A C4B	2.78e-04	71	130	4	C0024141
Disease	Colorectal Carcinoma	NRCAM CALR NTNG1 APOB LIFR SACS VPS13A SPAG17 ZNF471 ANAPC4 PRPS1	2.87e-04	702	130	11	C0009402
Disease	stomach cancer (is_implicated_in)	ACE CHRNA3 MAP3K1 TMEM260	2.93e-04	72	130	4	DOID:10534 (is_implicated_in)
Disease	lung cancer (is_implicated_in)	CALR ACE CHRNA3 CSF1R	3.26e-04	74	130	4	DOID:1324 (is_implicated_in)
Disease	low affinity immunoglobulin gamma Fc region receptor II-a/b measurement	FCGR3A FCGR3B	3.99e-04	7	130	2	EFO_0008211
Disease	fatty liver disease (biomarker_via_orthology)	INSR APOB OPA1	4.14e-04	33	130	3	DOID:9452 (biomarker_via_orthology)
Disease	plexin-B2 measurement	FCGR3A FCGR3B	6.80e-04	9	130	2	EFO_0021867
Disease	lung cancer (is_marker_for)	CALR PRDM1 CSF1R	6.80e-04	39	130	3	DOID:1324 (is_marker_for)
Disease	systemic lupus erythematosus (implicated_via_orthology)	PRDM1 C4A C4B	9.07e-04	43	130	3	DOID:9074 (implicated_via_orthology)
Disease	Weight Gain	ACE ME1 LPGAT1 PRPS1	1.10e-03	102	130	4	C0043094
Disease	pulmonary function measurement, smoking behaviour measurement, FEV/FEC ratio	KERA CHRNA3 MMP15	1.18e-03	47	130	3	EFO_0003892, EFO_0004713, EFO_0005671
Disease	Celiac Disease	APOB ACE FCGR3A	1.18e-03	47	130	3	C0007570
Disease	Hematologic Neoplasms	CALR CSF1R	1.24e-03	12	130	2	C0376545
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	CHRNA6 CHRNA3	1.24e-03	12	130	2	C1861063
Disease	non-high density lipoprotein cholesterol measurement	KIF13B APOB ADTRP PRDM1 CSF1R PIGC FAR2 SUGP1 ZNF471 HYDIN	1.26e-03	713	130	10	EFO_0005689
Disease	lung adenocarcinoma (is_implicated_in)	CALR CHRNA3 PRDM1	1.33e-03	49	130	3	DOID:3910 (is_implicated_in)
Disease	depressive symptom measurement, stressful life event measurement	PCLO CNTN6 TMEM260	1.41e-03	50	130	3	EFO_0007006, EFO_0007781
Disease	Autosomal Dominant Myotubular Myopathy	BIN1 MTMR14	1.46e-03	13	130	2	C3661489
Disease	Centronuclear myopathy	BIN1 MTMR14	1.46e-03	13	130	2	C0175709
Disease	X-linked centronuclear myopathy	BIN1 MTMR14	1.46e-03	13	130	2	C0410203
Disease	Myopathy, Centronuclear, 1	BIN1 MTMR14	1.46e-03	13	130	2	C4551952
Disease	Cakut	CHRNA3 LIFR	1.46e-03	13	130	2	C1968949
Disease	Congenital Structural Myopathy	BIN1 MTMR14	1.46e-03	13	130	2	C0752282
Disease	serum alanine aminotransferase measurement	FOXN2 PCLO INSR NTNG1 APOB MAP3K1 ADAMTS7 FCGR3A FCGR3B SUGP1 MMP15	1.64e-03	869	130	11	EFO_0004735
Disease	Myopathy, Centronuclear, Autosomal Dominant	BIN1 MTMR14	1.69e-03	14	130	2	C1834558
Disease	low affinity immunoglobulin gamma Fc region receptor III-B measurement	FCGR3A FCGR3B	1.69e-03	14	130	2	EFO_0008212
Disease	Tubular Aggregate Myopathy	BIN1 MTMR14	1.69e-03	14	130	2	C0410207
Disease	low density lipoprotein triglyceride measurement	APOB SUGP1	1.95e-03	15	130	2	EFO_0009946
Disease	allergic disease (is_implicated_in)	ACE FCGR3A	1.95e-03	15	130	2	DOID:1205 (is_implicated_in)
Disease	lung small cell carcinoma (is_marker_for)	CHRNA3 CSF1R	2.22e-03	16	130	2	DOID:5409 (is_marker_for)
Disease	pneumonia (is_implicated_in)	ACE FCGR3A	2.22e-03	16	130	2	DOID:552 (is_implicated_in)
Disease	hepatocellular carcinoma (is_marker_for)	CALR INSR CBX4 MAP3K1 PRDM1 CSF1R	2.22e-03	301	130	6	DOID:684 (is_marker_for)
Disease	ocular hypertension (biomarker_via_orthology)	OPA1 SMO	2.51e-03	17	130	2	DOID:9282 (biomarker_via_orthology)
Disease	pre-malignant neoplasm (biomarker_via_orthology)	INSR SMO	2.51e-03	17	130	2	DOID:0060071 (biomarker_via_orthology)
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	FCGR3A FCGR3B	2.51e-03	17	130	2	EFO_0021969
Disease	respiratory symptom change measurement, response to placebo	CNTN6 DHX15	2.51e-03	17	130	2	EFO_0008344, EFO_0010068
Disease	systemic lupus erythematosus (is_implicated_in)	FCGR3A C4A C4B	2.61e-03	62	130	3	DOID:9074 (is_implicated_in)
Disease	Congenital Fiber Type Disproportion	BIN1 MTMR14	2.81e-03	18	130	2	C0546264
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	APOB SUGP1	2.81e-03	18	130	2	EFO_0008317, EFO_0008589
Disease	Seizures	CUL4B CHRNA3 NRP2 PCYT2 MACF1	2.85e-03	218	130	5	C0036572
Disease	Malignant neoplasm of breast	NRCAM SMARCAL1 LRRC37A2 HLCS MAP3K1 CNTN6 LRRC37A CSF1R MTMR3 MACF1 TOP2A PRPS1	2.86e-03	1074	130	12	C0006142
Disease	Coronary Arteriosclerosis	ADTRP ACE ADAMTS7	2.99e-03	65	130	3	C0010054
Disease	Coronary Artery Disease	ADTRP ACE ADAMTS7	2.99e-03	65	130	3	C1956346
Disease	prostate adenocarcinoma (is_implicated_in)	BIN1 INSR	3.47e-03	20	130	2	DOID:2526 (is_implicated_in)
Disease	chronic obstructive pulmonary disease	SETD1A SPEG LRRC37A2 TSPY26P CHRNA3 NRP2 MTMR3 MMP15 VARS1	3.50e-03	688	130	9	EFO_0000341
Disease	renal cell carcinoma (is_implicated_in)	CSF1R C4A C4B	3.54e-03	69	130	3	DOID:4450 (is_implicated_in)
Disease	dentures	OPA1 CHRNA3 MTMR3	3.69e-03	70	130	3	EFO_0010078
Disease	dental caries, dentures	OPA1 CHRNA3 MTMR3	3.69e-03	70	130	3	EFO_0003819, EFO_0010078
Disease	Psychoses, Drug	CALR ACE	3.83e-03	21	130	2	C0033937
Disease	vitiligo (is_implicated_in)	NLRP1 C4A	3.83e-03	21	130	2	DOID:12306 (is_implicated_in)
Disease	Sclerocystic Ovaries	LIFR ADAMTS7 RP2 TOP2A	3.84e-03	144	130	4	C1136382
Disease	Polycystic Ovary Syndrome	LIFR ADAMTS7 RP2 TOP2A	3.84e-03	144	130	4	C0032460

Protein segments in the cluster

Peptide	Gene	Start	Entry
QVWPELTELPDYNKI	CDK20	226	Q8IZL9
EKQLPQEIIFLVWSP	ANAPC4	16	Q9UJX5
DDWVQEYIKDPNLPL	CCL16	81	O15467
RYLDKTEQWSTLPPE	C4B	1026	P0C0L5
VPAQKIWKPDIVLYN	CHRNA3	111	P32297
AKELYEPIWQNFTDP	ACE	101	P12821
VPINDNYCEKLLPWL	DUSP8	211	Q13202
DLIYPKVLDTVIPVW	ADTRP	111	Q96IZ2
WQKIEELARLNPQYP	PPP2R5D	506	Q14738
LYPTEKIIWDENIVP	AQR	426	O60306
TDIKPEWLVKIAPQY	DHX15	751	O43143
YIWSLKDLAQPPQRV	DENND3	1101	A2RUS2
INYRWELEEGKPNPL	CECR2	86	Q9BXF3
FWPEEETSLQVYKPL	ARMCX5	186	Q6P1M9
KEPVWIQLLFQESNP	ADAMTS7	786	Q9UKP4
QLLEELDKTPWQYPP	HACL1	331	Q9UJ83
RQIYPQLKKWEQDPE	HIBCH	66	Q6NVY1
NVWLYDVSNILKQPP	LRWD1	576	Q9UFC0
PSEKIWRPDLVLYNN	CHRNA1	101	P02708
EITPKLIRDWPNIYT	FAR2	191	Q96K12
ESPDLLKPWETYNQN	KIF14	1586	Q15058
EAQPLEWVKDPLQLT	LRRC37A3	36	O60309
WIIDTTIAYPKAEPI	LPGAT1	251	Q92604
TIAYPKAEPIDIQTW	LPGAT1	256	Q92604
QILPDCYSWPEEVQK	ME1	551	P48163
LLLEIYPEWNPDNDT	MATR3	321	P43243
EAQPLEWVKDPLQLT	LRRC37A2	36	A6NM11
EAQPLEWVKDPLQLT	LRRC37A	36	A6NMS7
LKEPQWKYPDISDSI	MGA	546	Q8IWI9
EIKDPTWIVKQPEYA	NRCAM	541	Q92823
NWKQDYVDAPLSIPD	MTMR14	271	Q8NCE2
PLIGLPNTQDYKWVD	ERVMER34-1	201	Q9H9K5
WEQATPLVFQEVPYE	MMP15	171	P51511
PPKWSEQSDYLELLV	LAIR1	106	Q6GTX8
WPNGLTIDLEEQKLY	LRP5	196	O75197
IPEYQDINLRVKWPN	HLCS	556	P50747
LDNTPRWYPLKEQTE	PCLO	4816	Q9Y6V0
QAIKWVDEVVPAAPY	PCYT2	81	Q99447
SQDPLVKRSWPDYVE	NLRP1	291	Q9C000
EWNDQKQIAVYLPPT	CST9LP1	36	Q5W188
NEVLSWKLVPDNYPP	MSL3	426	Q8N5Y2
EWIVYAPEPNQKIVL	NRP2	56	O60462
PKKYSLDPEEIENWV	MEGF8	2326	Q7Z7M0
RILNWLKEEYNDPPI	LCT	1731	P09848
WQEPKEPNGLIVLYE	INSR	871	P06213
QVKPYLLSQEIPPDW	PDIA2	371	Q13087
PLAQIAEDKPYAELW	MPI	36	P34949
TILYDLLVNTEWPPE	NBAS	21	A2RRP1
PFQRVIQPEEIWLYK	PLPP4	26	Q5VZY2
IQPEEIWLYKNPLVQ	PLPP4	31	Q5VZY2
IWLYKNPLVQSDNIP	PLPP4	36	Q5VZY2
PEIWENLPYNNKSDI	NEK3	171	P51956
WLYKVEPQLAEDQPV	MACF1	6676	Q9UPN3
IPDLSEYKWIVPDIV	OPA1	126	O60313
AENLIEYKWPPDETG	PHF10	71	Q8WUB8
DLVYQQWTESRKPTP	PAPPA2	831	Q9BXP8
PADKIWKPDIVLYNN	CHRNA6	111	Q15825
NSELQWPVPDIYLRD	APOB	2681	P04114
WPVPDIYLRDLKVED	APOB	2686	P04114
VLQVWDDPYPEVLSQ	CSF1R	446	P07333
ALKQQDYLSLPPWEV	CSF2RB	876	P32927
LKPNEKQILNVWAYP	HYDIN	2886	Q4G0P3
LPSPQKEWYRLTEEE	IGSF3	1086	O75054
FTWKRPIYPVEELEE	IFT57	161	Q9NWB7
DVYPVLDTPAKQVLW	GRID2IP	431	A4D2P6
ITNDKWEFVDPYPVN	KLHL15	401	Q96M94
AEYLTRKEAVQWEPP	DOCK9	1646	Q9BZ29
EKPREQWILDYPAQV	DNAH17	1681	Q9UFH2
PLKTPEAELLWEVYL	C7orf61	146	Q8IZ16
YWAIDTNPKEDVLPT	FOXJ3	151	Q9UPW0
NAQKILVTPWDYRIP	DIS3L	361	Q8TF46
SPKYNTWEPEENILD	CBX4	36	O00257
IQNPEYKGEWKPRQI	CALR	266	P27797
VKYPLEKELPNFWEQ	CPD	766	O75976
PYQSWELRPLDVNKV	DNAI7	501	Q6TDU7
QLIFYAPPEWEQKIQ	CNTN6	311	Q9UQ52
EDLPKAVVFLEPQWY	FCGR3B	21	O75015
LWCVDPEYKPNLIQA	FOXN2	186	P32314
LWLIPPQAYLNVEKD	CUL9	1846	Q8IWT3
EDLPKAVVFLEPQWY	FCGR3A	21	P08637
KLNECLQEVYEPDWP	BIN1	81	O00499
QPDSLKPYAEDIWAL	CAND2	926	O75155
DYILETWTPPQVLQD	SEC14L1	311	Q92503
ENPNVLEWLTPLKFI	SACS	1026	Q9NZJ4
FSWQLLQPDKVPEIQ	IPO13	61	O94829
PKLPENYTDETWQKL	CUL4B	206	Q13620
RYLDKTEQWSTLPPE	C4A	1026	P0C0L4
NLIIYWKPLPINEAN	LIFR	551	P42702
QLLWDPEYLPEDKVI	MIER1	211	Q8N108
YPQELIVPAWITDKE	MTMR3	191	Q13615
WKEPLDPNGIITQYE	PTPRK	511	Q15262
ISEWEQKIPTYNTPL	KIF23	726	Q02241
TQQIPPAYKDLAEPW	MAP3K1	546	Q13233
ATWKEYPKPLQVNIT	NTNG1	121	Q9Y2I2
WNQLSLLPVPYSKEQ	GLMN	151	Q92990
KYSFWDQQEPVIVAP	KIF13B	891	Q9NQT8
SKDVVEPLLRPQWYV	VARS1	666	P26640
KPPTEDELQQQIKYW	RGS7	251	P49802
PWVEKYRPQTLNDLI	RFC5	21	P40937
KPWYSIFPIDNEDLV	TAF1L	481	Q8IZX4
TFEPIYPERLWIEEK	GUCY1B2	176	O75343
IPEKPFENATQLRWI	KERA	86	O60938
GTADDYLWPLIQEKI	SMARCAL1	836	Q9NZC9
WEVVAYDDPKIPLFN	PUS7	586	Q96PZ0
TPSIWPQEILAKYTQ	SGSM3	16	Q96HU1
IKDDIWPNPLQYYLV	SETSIP	231	P0DME0
IKDDIWPNPLQYYLV	SET	221	Q01105
TIKPIPANQELLVWY	PRDM1	186	O75626
PKLYIVNLQWTPKDD	SIRT7	291	Q9NRC8
EVKWQKVLYERQPFP	PIGC	11	Q92535
ALIIIDWIYDPPNSK	SLC38A4	531	Q969I6
PVDNLYAEPTVLKWI	PRPS1L1	141	P21108
YAEPTVLKWIRENIP	PRPS1L1	146	P21108
QWRNYKLIVDPALDP	SETD1A	16	O15047
ENLRTPWKPKYFIQE	OSBPL10	736	Q9BXB5
DYVPSENDLQPLLAW	RRP12	376	Q5JTH9
WKYLEPVLNNEKPET	SPAG17	296	Q6Q759
VSILIPENWKENPQY	CLCA4	76	Q14CN2
DYEQWLEIKVSPPEG	SUGP1	171	Q8IWZ8
KLIIPWKNLYTQPVE	VPS13A	66	Q96RL7
WKNLYTQPVEAVLEE	VPS13A	71	Q96RL7
VPQTYQDTALVLWKP	SPEG	2686	Q15772
DVYRINPQAEWVIKP	ARHGAP28	711	Q9P2N2
YVWTVKEVQQLLPEP	SPATA20	401	Q8TB22
PVDNLYAEPAVLQWI	PRPS2	141	P11908
EEEWQLLGPLEKTLY	ZNF75CP	216	Q92670
WSLLPEDAVVQDYVP	RP2	186	O75695
YELVKSQQWDDIPPI	TENM3	2436	Q9P273
PLVRTDNPKSWYEDV	SMO	196	Q99835
DDNQRVEPEWYIPII	TOP2A	831	P11388
DWESIYVTQELPLKQ	ZNF471	86	Q9BX82
KPNVISYLEQGKEPW	ZNF566	51	Q969W8
PVDNLYAEPAVLKWI	PRPS1	141	P60891
PEIAAVPELAKYWAQ	TGS1	636	Q96RS0
WVPREPYILQTSEDK	WDR31	196	Q8NA23
QIIKDDLWPNPLQYY	TSPY26P	311	Q9H489
YVQLENQWETPPEDL	ZNF449	266	Q6P9G9
IQSLLDEFWKNPPVL	VPS37A	116	Q8NEZ2
KLVPLEIVFNPEEWI	TMEM260	546	Q9NX78
EDLLAPISEPIEWKY	NADSYN1	311	Q6IA69
PWTLIDFYDNQPVID	MYO5C	481	Q9NQX4