Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF789 ZNF517 ZNF732 ZNF337 ZNF652 MAZ ARX ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ST18 ZNF692

5.45e-1214128828GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF789 ZNF517 ZNF732 ZNF337 ZNF652 MAZ ARX ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZNF623 ST18 ZNF692

1.19e-1114598828GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF789 ZNF732 ZNF652 MAZ ARX ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF623 ST18 ZNF692

7.75e-1112448825GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF789 ZNF732 ZNF652 MAZ ARX ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF623 ST18 ZNF692

1.22e-1012718825GO:0000987
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5B KDM5C KDM5D

1.64e-066883GO:0034647
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5B KDM5C KDM5D

4.56e-068883GO:0032453
GeneOntologyMolecularFunctionreelin receptor activity

VLDLR LRP8

1.92e-052882GO:0038025
GeneOntologyMolecularFunctiongrowth factor binding

THBS1 EGFR PCSK6 WFIKKN2 ITGAV IL6ST

6.60e-05156886GO:0019838
GeneOntologyMolecularFunctionvery-low-density lipoprotein particle receptor activity

VLDLR LRP8

1.15e-044882GO:0030229
GeneOntologyMolecularFunctiontransforming growth factor beta binding

THBS1 WFIKKN2 ITGAV

2.00e-0426883GO:0050431
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM5B KDM5C KDM5D

2.50e-0428883GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM5B KDM5C KDM5D

3.40e-0431883GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM5B KDM5C KDM5D

3.74e-0432883GO:0140457
GeneOntologyMolecularFunctionlipoprotein particle binding

VLDLR THBS1 LRP8

4.89e-0435883GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

VLDLR THBS1 LRP8

4.89e-0435883GO:0071814
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

ZNF134 SP3 ZNF668 ARX ZNF350 ZNF782 ZNF692

5.32e-04320887GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

ZNF134 SP3 ZNF668 ARX ZNF350 ZNF782 ZNF692

5.94e-04326887GO:0001217
GeneOntologyMolecularFunctiondemethylase activity

KDM5B KDM5C KDM5D

9.61e-0444883GO:0032451
GeneOntologyMolecularFunctionintegrin binding

THBS1 EGFR ITGAV ITGB2 ITGB6

1.06e-03175885GO:0005178
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN3A

1.69e-0314882GO:0031402
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP8

2.21e-0316882GO:0005041
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5B KDM5C KDM5D

2.97e-0365883GO:0016706
GeneOntologyMolecularFunctionhistone modifying activity

KDM5B SETD2 KDM5C KDM5D KMT2E

3.44e-03229885GO:0140993
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP8

3.46e-0320882GO:0034185
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP8

3.82e-0321882GO:0030228
GeneOntologyCellularComponentintegrin alphav-beta6 complex

ITGAV ITGB6

1.83e-052902GO:0034685
GeneOntologyCellularComponentstriated muscle myosin thick filament

TRIM32 MYBPC3

1.09e-044902GO:0005863
GeneOntologyCellularComponentintegrin complex

ITGAV ITGB2 ITGB6

3.50e-0432903GO:0008305
GeneOntologyCellularComponentfibrinogen complex

THBS1 FGL2

5.05e-048902GO:0005577
GeneOntologyCellularComponentcell surface

VLDLR THBS1 HEG1 EGFR LMO7 PCSK6 ADAM29 ADGRE1 ITGAV ITGB2 ITGB6 IL6ST LRP8

9.17e-0411119013GO:0009986
Domain-

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

5.32e-1967990283.30.160.60
Domainzf-C2H2

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

9.10e-196939028PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

9.45e-196949028IPR013087
DomainZINC_FINGER_C2H2_2

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

1.50e-187759029PS50157
DomainZINC_FINGER_C2H2_1

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

1.61e-187779029PS00028
DomainZnf_C2H2

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

4.17e-188059029IPR007087
DomainZnF_C2H2

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

4.61e-188089029SM00355
DomainZnf_C2H2-like

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

3.36e-177969028IPR015880
DomainKRAB

ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF732 ZNF337 ZNF189 ZNF432 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 ZNF700

1.14e-123589017PS50805
DomainKRAB

ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF732 ZNF337 ZNF189 ZNF432 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 ZNF700

1.14e-123589017PF01352
DomainKRAB

ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF732 ZNF337 ZNF189 ZNF432 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 ZNF700

1.86e-123699017SM00349
DomainKRAB

ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF732 ZNF337 ZNF189 ZNF432 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 ZNF700

1.94e-123709017IPR001909
Domainzf-C2H2_6

ZNF668 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF532 ZNF732 ZNF652 ZNF432 ZNF571 ZNF84 ZNF782 ZNF317 RREB1 ZNF700

1.95e-123149016PF13912
DomainEGF-like_dom

VLDLR THBS1 HEG1 IMPG1 PCSK6 SLIT1 ADAM29 C6 ADGRE1 LRP8

3.33e-072499010IPR000742
DomainEGF_1

VLDLR THBS1 HEG1 SLIT1 ADAM29 C6 ADGRE1 ITGB2 ITGB6 LRP8

4.14e-072559010PS00022
DomainLys_sp_deMease-like_dom

KDM5B KDM5C KDM5D

4.31e-074903IPR013637
DomainPLU-1

KDM5B KDM5C KDM5D

4.31e-074903PF08429
DomainEGF-like_CS

VLDLR THBS1 HEG1 SLIT1 ADAM29 C6 ADGRE1 ITGB2 ITGB6 LRP8

5.13e-072619010IPR013032
DomainEGF_2

VLDLR THBS1 HEG1 SLIT1 ADAM29 C6 ADGRE1 ITGB2 ITGB6 LRP8

5.89e-072659010PS01186
Domainzf-C5HC2

KDM5B KDM5C KDM5D

1.07e-065903PF02928
DomainZnf_C5HC2

KDM5B KDM5C KDM5D

1.07e-065903IPR004198
DomainJmjN

KDM5B KDM5C KDM5D

1.27e-0510903SM00545
DomainJMJN

KDM5B KDM5C KDM5D

1.27e-0510903PS51183
DomainJmjN

KDM5B KDM5C KDM5D

1.27e-0510903PF02375
DomainJmjN

KDM5B KDM5C KDM5D

1.27e-0510903IPR003349
DomainEGF_3

VLDLR THBS1 HEG1 SLIT1 ADAM29 C6 ADGRE1 LRP8

1.78e-05235908PS50026
DomainEGF_CA

VLDLR THBS1 HEG1 SLIT1 ADGRE1 LRP8

2.73e-05122906SM00179
DomainEGF-like_Ca-bd_dom

VLDLR THBS1 HEG1 SLIT1 ADGRE1 LRP8

2.99e-05124906IPR001881
Domain-

KDM5B KDM5C KDM5D

4.72e-05159031.10.150.60
DomainBRIGHT

KDM5B KDM5C KDM5D

4.72e-0515903SM00501
DomainARID_dom

KDM5B KDM5C KDM5D

4.72e-0515903IPR001606
DomainARID

KDM5B KDM5C KDM5D

4.72e-0515903PS51011
DomainARID

KDM5B KDM5C KDM5D

4.72e-0515903PF01388
DomainEGF_CA

VLDLR THBS1 HEG1 ADGRE1 LRP8

5.95e-0586905PF07645
DomainEGF_Ca-bd_CS

VLDLR HEG1 SLIT1 ADGRE1 LRP8

1.06e-0497905IPR018097
DomainGrowth_fac_rcpt_

VLDLR EGFR PCSK6 SLIT1 ADGRE1 LRP8

1.08e-04156906IPR009030
DomainEGF_CA

VLDLR HEG1 SLIT1 ADGRE1 LRP8

1.16e-0499905PS01187
DomainALBUMIN

AFM GC

1.37e-044902SM00103
DomainSerum_albumin_N

AFM GC

1.37e-044902IPR014760
DomainALBUMIN_1

AFM GC

1.37e-044902PS00212
DomainSerum_albumin_CS

AFM GC

1.37e-044902IPR020857
DomainSerum_albumin

AFM GC

1.37e-044902PF00273
DomainALBUMIN_2

AFM GC

1.37e-044902PS51438
DomainEGF

VLDLR THBS1 HEG1 PCSK6 SLIT1 ADGRE1 LRP8

1.41e-04235907SM00181
DomainEGF-type_Asp/Asn_hydroxyl_site

VLDLR HEG1 SLIT1 ADGRE1 LRP8

1.60e-04106905IPR000152
DomainJmjC

KDM5B KDM5C KDM5D

2.04e-0424903PF02373
DomainSerum_albumin-like

AFM GC

2.27e-045902IPR020858
DomainIntegrin_dom

ITGAV ITGB2 ITGB6

2.30e-0425903IPR032695
DomainZinc_finger_PHD-type_CS

KDM5B KDM5C KDM5D KMT2E

2.73e-0465904IPR019786
Domain-

KDM5B TRIM32 SH3RF2 KDM5C HGS RNF213 KDM5D KMT2E MUL1

3.12e-044499093.30.40.10
DomainNa_trans_cytopl

SCN1A SCN3A

3.40e-046902PF11933
DomainIntegrin_bsu_cyt_dom

ITGB2 ITGB6

3.40e-046902IPR014836
DomainGF_recep_IV

EGFR PCSK6

3.40e-046902PF14843
DomainGF_recep_IV

EGFR PCSK6

3.40e-046902IPR032778
DomainIntegrin_b_cyt

ITGB2 ITGB6

3.40e-046902SM01241
DomainIntegrin_b_cyt

ITGB2 ITGB6

3.40e-046902PF08725
DomainALB/AFP/VDB

AFM GC

3.40e-046902IPR000264
DomainNa_trans_cytopl

SCN1A SCN3A

3.40e-046902IPR024583
DomainZnf_RING/FYVE/PHD

KDM5B TRIM32 SH3RF2 KDM5C HGS RNF213 KDM5D KMT2E MUL1

3.67e-04459909IPR013083
DomainPHD

KDM5B KDM5C KDM5D KMT2E

4.72e-0475904PF00628
DomainIntegrin_bsu_tail

ITGB2 ITGB6

4.75e-047902IPR012896
DomainIntegrin_B_tail

ITGB2 ITGB6

4.75e-047902SM01242
DomainIntegrin_B_tail

ITGB2 ITGB6

4.75e-047902PF07965
DomainJMJC

KDM5B KDM5C KDM5D

4.85e-0432903PS51184
DomainJmjC_dom

KDM5B KDM5C KDM5D

4.85e-0432903IPR003347
DomainJmjC

KDM5B KDM5C KDM5D

5.32e-0433903SM00558
DomainZnf_PHD-finger

KDM5B KDM5C KDM5D KMT2E

5.75e-0479904IPR019787
DomainIntegrin_beta

ITGB2 ITGB6

6.31e-048902PF00362
DomainINB

ITGB2 ITGB6

6.31e-048902SM00187
DomainIntegrin_bsu_VWA

ITGB2 ITGB6

6.31e-048902IPR002369
DomainZnf_FYVE_PHD

KDM5B KDM5C HGS KDM5D KMT2E

7.25e-04147905IPR011011
DomainIntegrin_bsu

ITGB2 ITGB6

8.09e-049902IPR015812
DomainIntegin_beta_N

ITGB2 ITGB6

8.09e-049902IPR033760
DomainINTEGRIN_BETA

ITGB2 ITGB6

8.09e-049902PS00243
DomainPSI_integrin

ITGB2 ITGB6

8.09e-049902PF17205
Domain-

VLDLR TRIM32 LRP8

8.72e-04399032.120.10.30
DomainPHD

KDM5B KDM5C KDM5D KMT2E

9.01e-0489904SM00249
DomainLDLR_class-A_CS

VLDLR C6 LRP8

9.40e-0440903IPR023415
DomainZnf_PHD

KDM5B KDM5C KDM5D KMT2E

9.79e-0491904IPR001965
DomainNa_channel_asu

SCN1A SCN3A

1.01e-0310902IPR001696
DomainNa_trans_assoc

SCN1A SCN3A

1.01e-0310902IPR010526
DomainNa_trans_assoc

SCN1A SCN3A

1.01e-0310902PF06512
DomainZF_PHD_2

KDM5B KDM5C KDM5D KMT2E

1.15e-0395904PS50016
DomainZF_PHD_1

KDM5B KDM5C KDM5D KMT2E

1.19e-0396904PS01359
DomainLdl_recept_a

VLDLR C6 LRP8

1.33e-0345903PF00057
DomainASX_HYDROXYL

VLDLR HEG1 ADGRE1 LRP8

1.39e-03100904PS00010
Domain6-blade_b-propeller_TolB-like

VLDLR TRIM32 LRP8

1.41e-0346903IPR011042
DomainLDLRA_1

VLDLR C6 LRP8

1.60e-0348903PS01209
DomainLDLRA_2

VLDLR C6 LRP8

1.70e-0349903PS50068
DomainLDrepeatLR_classA_rpt

VLDLR C6 LRP8

1.70e-0349903IPR002172
DomainLDLa

VLDLR C6 LRP8

1.70e-0349903SM00192
DomainLdl_recept_b

VLDLR LRP8

2.01e-0314902PF00058
DomainLDLRB

VLDLR LRP8

2.01e-0314902PS51120
DomainLY

VLDLR LRP8

2.31e-0315902SM00135
DomainLDLR_classB_rpt

VLDLR LRP8

2.31e-0315902IPR000033
DomainWAP

WFIKKN2 WFDC12

2.64e-0316902SM00217
DomainWAP

WFIKKN2 WFDC12

2.64e-0316902PF00095
DomainWAP

WFIKKN2 WFDC12

2.98e-0317902PS51390
Domain-

WFIKKN2 WFDC12

2.98e-03179024.10.75.10
DomainEGF

VLDLR HEG1 SLIT1 LRP8

3.23e-03126904PF00008
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

KDM5B ZNF668 THBS1 ZNF605 ZNF613 ZNF155 ZNF517 EGFR ZNF732 ZNF337 ZNF189 ZNF432 PPP1R13B ZNF571 ZNF350 ZNF782 ZNF317 ZNF700 ZNF692

1.23e-0513876619M734
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL6A3 THBS1 ITGAV ITGB2 ITGB6

2.76e-0576665MM14867
PathwayPID_UPA_UPAR_PATHWAY

VLDLR EGFR ITGAV ITGB2

4.29e-0542664M174
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

COL6A3 THBS1 ITGAV ITGB2 ITGB6

4.74e-0585665M16441
PathwayPID_INTEGRIN_CS_PATHWAY

ITGAV ITGB2 ITGB6

2.36e-0426663M47
PathwayBIOCARTA_EEA1_PATHWAY

EGFR HGS

3.20e-046662MM1577
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM5B KDM5C KDM5D

3.28e-0429663MM14934
PathwayBIOCARTA_REELIN_PATHWAY

VLDLR LRP8

4.47e-047662MM1566
PathwayBIOCARTA_REELIN_PATHWAY

VLDLR LRP8

4.47e-047662M22049
PathwayBIOCARTA_EEA1_PATHWAY

EGFR HGS

4.47e-047662M22064
PathwayKEGG_ECM_RECEPTOR_INTERACTION

COL6A3 THBS1 ITGAV ITGB6

6.38e-0484664M7098
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5B KDM5C KDM5D

6.69e-08490316541399
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5B KDM5C KDM5D

6.69e-08490317320160
Pubmed

Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration.

VLDLR THBS1 LRP8

1.67e-07590318946489
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

VLDLR KDM5B THBS1 ZNF605 PSAP ZNF532 LMO7 TRIM32 ATP13A1 PCSK6 ZNF189 OSBPL8 ZNF350 ZNF84 ST18 MTMR10

1.80e-071285901635914814
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VLDLR EGFR ITLN1 ITGB2 ITGB6 LRP8

2.64e-0710190623382219
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

COL6A3 THBS1 ATP13A1 AFM C6 ITGB2 IL6ST FGL2

3.66e-0725790816335952
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM5B SETD2 KDM5C KDM5D KMT2E

3.90e-075790518022353
Pubmed

Integrins.

ITGAV ITGB2 ITGB6

3.62e-061290319693543
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KDM5B KDM5C KDM5D

4.70e-061390324619213
Pubmed

Targeted in vivo imaging of integrin alphavbeta6 with an improved radiotracer and its relevance in a pancreatic tumor model.

ITGAV ITGB6

6.62e-06290219549907
Pubmed

Study on the effect of Integrin αVβ6 on proliferation and apoptosis of cervical cancer cells.

ITGAV ITGB6

6.62e-06290228682441
Pubmed

Integrin alpha v beta 6 is an RGD-dependent receptor for coxsackievirus A9.

ITGAV ITGB6

6.62e-06290215194773
Pubmed

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

ITGAV ITGB6

6.62e-06290222232213
Pubmed

Study on the effect of integrin ανβ6 on the proliferation and apoptosis of thyroid carcinoma cells.

ITGAV ITGB6

6.62e-06290228730778
Pubmed

Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.

ITGAV ITGB6

6.62e-06290220838674
Pubmed

Integrin alphaVbeta6 is a high-affinity receptor for coxsackievirus A9.

ITGAV ITGB6

6.62e-06290219088289
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5C KDM5D

6.62e-06290210441747
Pubmed

Integrin αvβ6 contributes to the development of intestinal fibrosis via the FAK/AKT signaling pathway.

ITGAV ITGB6

6.62e-06290234979108
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5C KDM5D

6.62e-06290216416087
Pubmed

Stable Peptides Instead of Stapled Peptides: Highly Potent αvβ6-Selective Integrin Ligands.

ITGAV ITGB6

6.62e-06290226663660
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

6.62e-06290224990319
Pubmed

The reelin receptors VLDLR and ApoER2 regulate sensorimotor gating in mice.

VLDLR LRP8

6.62e-06290217261317
Pubmed

The UIM domain of Hrs couples receptor sorting to vesicle formation.

EGFR HGS

6.62e-06290212953068
Pubmed

αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease.

ITGAV ITGB6

6.62e-06290225745053
Pubmed

Integrin alpha v beta 6 mediates the potential for colon cancer cells to colonize in and metastasize to the liver.

ITGAV ITGB6

6.62e-06290218294287
Pubmed

Periodontal pathogens invade gingiva and aortic adventitia and elicit inflammasome activation in αvβ6 integrin-deficient mice.

ITGAV ITGB6

6.62e-06290226371120
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5C KDM5D

6.62e-06290232081420
Pubmed

ApoER2 and VLDLR in the developing human telencephalon.

VLDLR LRP8

6.62e-06290221601501
Pubmed

Integrin αvβ6 plays a bi-directional regulation role between colon cancer cells and cancer-associated fibroblasts.

ITGAV ITGB6

6.62e-06290230355650
Pubmed

Integrin alpha v beta 6 contributes to maintaining corneal epithelial barrier function.

ITGAV ITGB6

6.62e-06290223412966
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

6.62e-06290227690330
Pubmed

Hypoxia increases reepithelialization via an alphavbeta6-dependent pathway.

ITGAV ITGB6

6.62e-06290215828940
Pubmed

Integrin alphavbeta6 is involved in measles protein-induced airway immune suppression.

ITGAV ITGB6

6.62e-06290222579114
Pubmed

Differential Action of Reelin on Oligomerization of ApoER2 and VLDL Receptor in HEK293 Cells Assessed by Time-Resolved Anisotropy and Fluorescence Lifetime Imaging Microscopy.

VLDLR LRP8

6.62e-06290230873003
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

6.62e-06290223965409
Pubmed

Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus.

ITGAV ITGB6

6.62e-06290228534487
Pubmed

Expression of integrin ανβ6 differentiates perihilar cholangiocarcinoma (PHC) from benign disease mimicking PHC.

ITGAV ITGB6

6.62e-06290233069505
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5C KDM5D

6.62e-0629027524912
Pubmed

Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence.

ITGAV ITGB6

6.62e-06290224150233
Pubmed

Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling.

ITGB2 ITGB6

6.62e-06290224175614
Pubmed

The relationship between integrin avß6 and HBV infection in patients with liver cirrhosis and hepatocellular carcinoma: a preliminary report.

ITGAV ITGB6

6.62e-06290232450701
Pubmed

Overexpression of the alphavbeta6 integrin in endometrial cancer.

ITGAV ITGB6

6.62e-06290218698261
Pubmed

Critical role for αvβ6 integrin in enamel biomineralization.

ITGAV ITGB6

6.62e-06290223264742
Pubmed

Alcohol-associated fibrosis in females is mediated by female-specific activation of lysine demethylases KDM5B and KDM5C.

KDM5B KDM5C

6.62e-06290235468265
Pubmed

Phosphorylation of Hrs downstream of the epidermal growth factor receptor.

EGFR HGS

6.62e-06290212180964
Pubmed

Ad5NULL-A20: A Tropism-Modified, αvβ6 Integrin-Selective Oncolytic Adenovirus for Epithelial Ovarian Cancer Therapies.

ITGAV ITGB6

6.62e-06290229798908
Pubmed

The Reelin receptors Apoer2 and Vldlr coordinate the patterning of Purkinje cell topography in the developing mouse cerebellum.

VLDLR LRP8

6.62e-06290218301736
Pubmed

Integrin αvβ6 mediates epithelial-mesenchymal transition in human bronchial epithelial cells induced by lipopolysaccharides of Pseudomonas aeruginosa via TGF-β1-Smad2/3 signaling pathway.

ITGAV ITGB6

6.62e-06290231243731
Pubmed

Role of integrin alphav beta6 in acute lung injury induced by Pseudomonas aeruginosa.

ITGAV ITGB6

6.62e-06290218378634
Pubmed

Characterization of integrin beta6 and thrombospondin-1 double-null mice.

THBS1 ITGB6

6.62e-06290215963261
Pubmed

Identification of functional segments within the beta2I-domain of integrin alphaMbeta2.

ITGAV ITGB2

6.62e-06290212324470
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5C KDM5D

6.62e-0629029060413
Pubmed

VLDLR and ApoER2 are receptors for multiple alphaviruses.

VLDLR LRP8

6.62e-06290234929721
Pubmed

Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1.

THBS1 PSAP

6.62e-06290219581582
Pubmed

Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies.

ITGAV ITGB6

6.62e-06290218221819
Pubmed

Knockout of integrin αvβ6 protects against renal inflammation in chronic kidney disease by reduction of pro-inflammatory macrophages.

ITGAV ITGB6

6.62e-06290238844455
Pubmed

Expression of αvβ6 integrin and collagen fibre in oral squamous cell carcinoma: association with clinical outcomes and prognostic implications.

ITGAV ITGB6

6.62e-06290223331428
Pubmed

Identification of the immunodominant HY H2-D(k) epitope and evaluation of the role of direct and indirect antigen presentation in HY responses.

ARX KDM5D

6.62e-06290216301625
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM5B KDM5C KDM5D KMT2E

8.13e-064990434368113
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

VLDLR SCN3A LRP8

1.33e-051890310827173
Pubmed

Reelin together with ApoER2 regulates interneuron migration in the olfactory bulb.

VLDLR LRP8

1.98e-05390223209795
Pubmed

The E3 ubiquitin ligase IDOL induces the degradation of the low density lipoprotein receptor family members VLDLR and ApoER2.

VLDLR LRP8

1.98e-05390220427281
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

VLDLR THBS1

1.98e-05390218032585
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A

1.98e-05390233895391
Pubmed

CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor.

EGFR HGS

1.98e-05390221635887
Pubmed

Regulation of ApoE receptor proteolysis by ligand binding.

VLDLR LRP8

1.98e-05390215950758
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN3A

1.98e-05390223859570
Pubmed

Disabled 1 Is Part of a Signaling Pathway Activated by Epidermal Growth Factor Receptor.

EGFR LRP8

1.98e-05390233572344
Pubmed

Hypoxia Promotes Resistance to EGFR Inhibition in NSCLC Cells via the Histone Demethylases, LSD1 and PLU-1.

KDM5B EGFR

1.98e-05390229934325
Pubmed

Functional consequences of hippocampal neuronal ectopia in the apolipoprotein E receptor-2 knockout mouse.

VLDLR LRP8

1.98e-05390218778775
Pubmed

GAPDH-mediated posttranscriptional regulations of sodium channel Scn1a and Scn3a genes under seizure and ketogenic diet conditions.

SCN1A SCN3A

1.98e-05390227816501
Pubmed

The integrin alphaVbeta6 binds and activates latent TGFbeta3.

ITGAV ITGB6

1.98e-05390211821050
Pubmed

Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.

ITGAV ITGB6

1.98e-0539028666675
Pubmed

Integrin alpha(v)beta6-associated ERK2 mediates MMP-9 secretion in colon cancer cells.

ITGAV ITGB6

1.98e-05390212177807
Pubmed

C-Terminal Region Truncation of RELN Disrupts an Interaction with VLDLR, Causing Abnormal Development of the Cerebral Cortex and Hippocampus.

VLDLR LRP8

1.98e-05390228123028
Pubmed

Abnormal positioning of granule cells alters afferent fiber distribution in the mouse fascia dentata: morphologic evidence from reeler, apolipoprotein E receptor 2-, and very low density lipoprotein receptor knockout mice.

VLDLR LRP8

1.98e-05390211920707
Pubmed

Linkage of open eyelids with linkage group VII of the mouse.

EGFR HGS

1.98e-0539025690495
Pubmed

Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry.

ITGAV ITGB6

1.98e-05390226157134
Pubmed

Integrins as triggers of Epstein-Barr virus fusion and epithelial cell infection.

ITGAV ITGB6

1.98e-05390221178476
Pubmed

Interaction of alphaVbeta3 and alphaVbeta6 integrins with human parechovirus 1.

ITGAV ITGB6

1.98e-05390220554778
Pubmed

Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.

KDM5B KDM5C

1.98e-05390238230606
Pubmed

Binding of purified Reelin to ApoER2 and VLDLR mediates tyrosine phosphorylation of Disabled-1.

VLDLR LRP8

1.98e-05390212670700
Pubmed

The Reelin receptors ApoER2 and VLDLR are direct target genes of HIC1 (Hypermethylated In Cancer 1).

VLDLR LRP8

1.98e-05390224076391
Pubmed

Up-regulation of ATP binding cassette transporter A1 expression by very low density lipoprotein receptor and apolipoprotein E receptor 2.

VLDLR LRP8

1.98e-05390222170052
Pubmed

Genomic alterations as predictors of survival among patients within a combined cohort with clear cell renal cell carcinoma undergoing cytoreductive nephrectomy.

SETD2 KDM5C

1.98e-05390228408295
Pubmed

Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production.

ITGAV ITGB6

1.98e-05390218349127
Pubmed

A role for Hrs in endosomal sorting of ligand-stimulated and unstimulated epidermal growth factor receptor.

EGFR HGS

1.98e-05390215212941
Pubmed

E6 Protein Expressed by High-Risk HPV Activates Super-Enhancers of the EGFR and c-MET Oncogenes by Destabilizing the Histone Demethylase KDM5C.

EGFR KDM5C

1.98e-05390229339538
Pubmed

Functional importance of covalent homodimer of reelin protein linked via its central region.

VLDLR LRP8

1.98e-05390221844191
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN3A

1.98e-05390212610651
Pubmed

Identification of key proteins of cultured human intestinal cells involved in interaction with enteroaggregative Escherichia coli.

THBS1 EGFR

1.98e-05390222672426
Pubmed

An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin.

THBS1 ITGAV

1.98e-0539022478219
Pubmed

D2A sequence of the urokinase receptor induces cell growth through αvβ3 integrin and EGFR.

EGFR ITGAV

1.98e-05390229184982
Pubmed

Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β1.

VLDLR LRP8

1.98e-05390223083738
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5C KDM5D

1.98e-0539027544442
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN3A

1.98e-05390218784617
Pubmed

Thrombospondin 1 and Reelin act through Vldlr to regulate cardiac growth and repair.

VLDLR THBS1

1.98e-05390238147128
Pubmed

Epidermal growth factor receptor-independent constitutive activation of STAT3 in head and neck squamous cell carcinoma is mediated by the autocrine/paracrine stimulation of the interleukin 6/gp130 cytokine system.

EGFR IL6ST

1.98e-05390212782602
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN3A

1.98e-05390217544618
Pubmed

Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation.

THBS1 EGFR

1.98e-05390221531776
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF134 SP3 ZNF668 ZNF594 ZNF182 ZNF605 ZNF613 ZNF155 ZNF789 ZNF517 ZNF532 ZNF732 ZNF337 ZNF652 MAZ ZNF189 ZNF432 ZFHX2 ZNF571 ZNF350 ZNF84 ZNF275 ZNF782 ZNF317 RREB1 ZNF700 ZBTB3 ZNF623 ZNF692

6.84e-21718792928
GeneFamilyAT-rich interaction domain containing

KDM5B KDM5C KDM5D

3.52e-0515793418
GeneFamilyPHD finger proteins|Lysine demethylases

KDM5B KDM5C KDM5D

1.52e-0424793485
GeneFamilyPHD finger proteins

KDM5B KDM5C KDM5D KMT2E

6.49e-049079488
GeneFamilyCD molecules|Integrin beta subunits

ITGB2 ITGB6

6.65e-0497921159
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN3A

6.65e-0497921203
GeneFamilyLow density lipoprotein receptors

VLDLR LRP8

1.43e-0313792634
GeneFamilyWAP four-disulfide core domain containing|Fibronectin type III domain containing

WFIKKN2 WFDC12

2.76e-0318792361
GeneFamilyRing finger proteins

ZFP36L1 TRIM32 SH3RF2 RNF213 MUL1

7.09e-0327579558
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD2 KMT2E

9.66e-0334792487
GeneFamilyComplement system|Sushi domain containing

C6 ITGB2

1.08e-0236792492
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_TFH-like|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

ZNF517 LMO7 CORO1B ADGRE1 ITGB2 IL6ST

2.58e-061929060f9cae41bb9bc9366efe9eb48e26b3e80c642879
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

EGFR SH3RF2 PCSK6 ZNF189 C6 RREB1

2.58e-06192906e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A WFDC12 FGL2

2.13e-05165905347b59aa625a8a960828b8620824d8ac48990e07
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A WFDC12 FGL2

2.13e-05165905507c89ece0a336b8e9c65b79889a714e17ddca27
ToppCellPND03-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A WFDC12 FGL2

2.13e-0516590539a25be081a5d59c7cf107a997d352793d5025fb
ToppCellPND03-Endothelial-Endothelial_lymphatic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A WFDC12 FGL2

2.13e-051659051890f9c33b0c5b381d57f97042da2610a093a6de
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LMO7 KDM5C SLIT1 OSBPL8 IL6ST

2.26e-05167905ced6ed9b412739c6ced622523347c10295edbf53
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

ZNF594 ZNF789 SH3RF2 LIN54 FGL2

2.68e-0517390562e0c18cfed9645e34a9d7029c94a8554f773714
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 SCN1A SCN3A ARX GC

2.99e-051779051dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 SCN1A SCN3A ARX GC

2.99e-05177905426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell367C-Lymphocytic-NK_cells-NK_cell_A|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PRKD3 HEG1 ZFP36L1 ITGB2

3.21e-0589904d8832dbe69d3490ceaa05ccc99d7c81707803925
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

COL6A3 ZFP36L1 LMO7 SH3RF2 ITGB6

3.50e-05183905dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 SCN3A SLIT1 ARX ST18

3.50e-05183905d26c7b79895de28961b8d68351f28d4bb531c75c
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 PSAP DNAJA4 ITGB2 FGL2

3.59e-05184905d7f348aa8901d819c68da20728b9238407bcdca9
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR ZNF605 ZNF155 DNAJA4 ARX

3.78e-05186905f5468e03321ea2083e223eb0d92c3a9307039569
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

THBS1 PSAP ZFP36L1 MUC19 FGL2

3.78e-0518690523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THBS1 ZNF613 PSAP ITGB2 FGL2

3.88e-0518790500930e407beaa337f72533a69f32d150faad8b9a
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 SCN3A ARX GC ST18

3.98e-05188905e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VLDLR LMO7 SH3RF2 AFM ITGB6

3.98e-051889052b8d70f761eda5509f21845a87cdb3602a639dd7
ToppCell(2)_Fibroblasts-(21)_Fibro-2|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

VLDLR EGFR PCSK6 ZFHX2 FGL2

4.19e-05190905d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCellfacs-Thymus-Epithelium-24m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 PCSK6 SCN3A ARX GC

4.29e-05191905eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 PCSK6 SCN3A ARX GC

4.29e-051919051730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 THBS1 EGFR PCSK6 SCN3A

4.29e-05191905b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 PCSK6 SCN3A ARX GC

4.29e-051919054b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

THBS1 PSAP ADGRE1 ITGB2 FGL2

4.29e-05191905c9f3bdb5c0a90268cab24a0fe4c3a8290fcedeb8
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

THBS1 PSAP ADGRE1 ITGB2 FGL2

4.40e-05192905b86476037ddf8904c1d8a6b3763af7242c031cf3
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 HEG1 EGFR PCSK6 FGL2

4.40e-05192905beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PRKD3 VLDLR ZNF182 KDM5C RALGAPB

4.51e-0519390508696a99309f5b088692ddac8cca35413b5e810d
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 THBS1 EGFR PCSK6 FGL2

4.51e-0519390545b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THBS1 PSAP ZFP36L1 ITGB2 FGL2

4.62e-05194905ce0486ce43748ffe486f08fdddd1f6acbfcc6b0e
ToppCellCOVID_vent-Myeloid-Monocytic-CD16+_Monocyte|COVID_vent / Disease condition, Lineage, Cell class and subclass

PSAP ITLN1 CORO1B ADGRE1 FGL2

4.62e-05194905b133d3d198360269cc449a75d34c29be377d91e0
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 PSAP ADGRE1 ITGB2 FGL2

4.74e-0519590501da7115e38c280fb0baff2032b62bdb609bad5e
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL6A3 THBS1 EGFR ZFP36L1 IL6ST

4.74e-05195905fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PSAP ZFP36L1 SKAP2 ITGB2 FGL2

4.97e-05197905e2c53742c7d8d1b63d93843f82330b9e20f1faa6
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-myeloid_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PSAP ZFP36L1 SKAP2 ITGB2 FGL2

4.97e-051979059838dbd1623babf8de7e9126a28fe5d3666bce42
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THBS1 PSAP ZFP36L1 ITGB2 FGL2

4.97e-05197905f807d8cd377ee58c02be7f71b39cd227f6b4f5df
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR COL6A3 HEG1 EGFR PCSK6

5.09e-051989050dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EGFR LMO7 SCN1A PPP1R13B ITGB6

5.22e-051999055f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THBS1 PSAP ZFP36L1 ITGB2 FGL2

5.22e-05199905e225c1bfc55947c30e7948be851daea04975efa5
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EGFR LMO7 SCN1A PPP1R13B ITGB6

5.22e-05199905725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EGFR LMO7 SCN1A PPP1R13B ITGB6

5.22e-051999058587bd98de7767a575088afbea07a1feb4516b9b
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 PSAP ADGRE1 ITGB2 FGL2

5.22e-05199905e12cea071e46436835cc22fe7badcbe878a1305b
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 PSAP ADGRE1 ITGB2 FGL2

5.22e-051999052ff5007b971c6fca9a9ef433e257739f0322a2a5
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LMO7 PPP1R13B ZNF84 ZBTB3 LRP8

5.22e-051999055db7c8089172ac8e796613b3cef618d87007a0ab
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

XKR9 LMO7 SH3RF2 ITGB6

9.65e-051189048d96a4879b28979fa04fbaeffa271a6b9ecbe867
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 SCN1A ZFHX2 ITGB6

1.32e-04128904003e133469899a9abe3a7f6d7f580583b281f412
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKR9 EGFR AFM PCSK6

1.81e-0413990482bf5ba69a907fbd9b4e2b2dd1dd27b8c4c75f25
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKR9 EGFR AFM PCSK6

1.81e-04139904fc9ac09c2106e88104a52575832d71d17765eec8
ToppCellfacs-Liver-Hepatocytes-3m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKR9 EGFR AFM PCSK6

1.81e-04139904fc4b39ac9a10cf0acacfebbc4295edf324d930d5
ToppCellfacs-Liver-Hepatocytes-3m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XKR9 EGFR AFM PCSK6

1.81e-041399044ddfbc36a0560fb70594627178bff652ab1ea3e9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SCN3A MTARC2 LRP8 MYBPC3

1.86e-04140904276b3fa924176426efb31112ed4d355407f0b218
ToppCellfacs-Skin-Anagen-3m-Myeloid|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6 ADGRE1 ITGB2 FGL2

2.02e-04143904250f60f06f262f00acd14b09b3ef90dbb9759336
ToppCellfacs-Skin-Anagen-3m-Myeloid-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6 ADGRE1 ITGB2 FGL2

2.02e-041439040c7c0d7ca040e87412295672cd1f065c0e941391
ToppCellfacs-Skin-Anagen-3m-Myeloid-macrophage|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6 ADGRE1 ITGB2 FGL2

2.02e-0414390427f4896276342758651fe7a80d7408ac5e1be9c0
ToppCellEpithelial-B_(AT1-AT2-progenitors)|World / shred on cell class and cell subclass (v4)

LMO7 PPP1R13B C6 ITGB6

2.19e-041469044511916904c1fac252cb68e871b782207f8137b3
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZNF182 ZNF652 LIN54 ZNF623

2.62e-04153904553dff9688a1996d8f4ba16e60c683593d781389
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cyth3_(Cyth3)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ZNF182 ZNF652 LIN54 ZNF623

2.62e-0415390488ca2d2c2ab19fbee13e18951b993ee05dd30f67
ToppCelldroplet-Bladder-nan-24m-Hematologic-macrophage|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6 ADGRE1 ITGB2 FGL2

2.96e-041589044a9d4706876f6e86fc5d63ad6dc7df1b4a5cfd9e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

EGFR LMO7 SH3RF2 MUC19

3.03e-041599048680b054622f573a82b1625fb93c2d5db81d1034
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.18e-04161904133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.18e-041619049466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.18e-04161904cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.25e-0416290496c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellCOVID-CD8-memory_CD4|COVID / Condition, Cell_class and T cell subcluster

ZNF594 ZNF517 PPP1R13B ZNF782

3.25e-0416290422b2a32217d357146c117e618813d451510a1801
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF532 C6 ADGRE1 ST18

3.33e-041639048dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF532 C6 ADGRE1 ST18

3.33e-04163904fd243ca223079033be480a24817a399f281fa4d4
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.41e-041649044cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THBS1 CORO1B ADGRE1 FGL2

3.41e-04164904f88871d3b9307112eb7ced4c629f5704326ecae8
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.41e-041649047a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.41e-041649045e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.41e-04164904f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellfacs-BAT-Fat-3m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 SKAP2 ITGB2 FGL2

3.49e-04165904bfe330751d34813af7540765b490406078c40da7
ToppCellfacs-BAT-Fat-3m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 SKAP2 ITGB2 FGL2

3.49e-041659048bdeacbb47948fabae2575689f811a9fad47f779
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ZNF594 MAZ PCSK6 ZBTB3

3.73e-041689048f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.82e-04169904f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA2 C6 ADGRE1 ITGB2

3.82e-041699040f5e737b265ba333275a0cd289dab029a1542075
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSAP SKAP2 ITGB2 FGL2

3.90e-041709043e52d40b0c36ab5b627a2dad025248901af8a320
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.90e-0417090435e3945d8a540a3e2cec1b559316265aaad023d1
ToppCellPND01-Endothelial-Endothelial_lymphatic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.90e-041709040ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCelldroplet-Thymus-nan-21m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 C6 ADGRE1 FGL2

3.90e-0417090429deb285d5a82c0abcc108012ca42f4b4b4d9e19
ToppCelldroplet-Thymus-nan-21m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMO7 C6 ADGRE1 FGL2

3.90e-04170904dc35d66a9a9fe6cdd7f4ec0fe7efa49d02f2b5b2
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN1A PCSK6 SCN3A FGL2

3.90e-041709040b5ddc7d452db0a389927a367914f7d257703f7e
ToppCellE12.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

THBS1 AFM PCSK6 GC

3.99e-04171904a4d6b0f57eead11b01153688b06b2a45a3b488f2
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SCN1A POFUT1 ZNF782 ZNF692

4.08e-04172904d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCellfacs-BAT-Fat-3m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 ADGRE1 SKAP2 ITGB2

4.08e-041729045f18c3f8eb8b7928901eede44c9b84b3c5efa1a9
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITLN1 WFIKKN2 SLIT1 ZNF275

4.17e-04173904e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

HEG1 EGFR LMO7 MTARC2

4.17e-041739043afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PSAP RNF213 ITGB2 ZMYM6

4.26e-04174904d5c22b43531414951666ee7542a66ed9380e2d14
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 COL6A3 SH3RF2 ADGRB2

4.26e-041749044da79da7a09ee1e345102c5331675ebcdbe56171
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR LMO7 SH3RF2 ITGB6

4.35e-0417590496219e58dcb327fd27190be78193e7a0d611e62b
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VLDLR LMO7 SH3RF2 ITGB6

4.35e-04175904cb974fbebe8cb58c7d3f7defabb4e056f2fee5fa
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_cell-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZNF532 ZNF189 MTARC2 KDM5D

4.35e-0417590469ed3c7c45df6bef70f5f2ff003531160bf3b32b
ToppCelldroplet-Liver-Npc-18m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAP C6 ADGRE1 ITGB2

4.35e-0417590492a4a3fd323ee8360edd659f9e16dfddc8788e2f
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 THBS1 EGFR PCSK6

4.45e-04176904fee4e0f32aaf77294040c7af6c1f503571750d43
ToppCellAT1-AT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

ZFP36L1 LMO7 ITGAV ITGB6

4.45e-04176904f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SCN3A ARX GC ST18

4.45e-04176904fb718a6b07aa5d56600263280afa530bcb63db42
ToppCellfacs-Heart-LV-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A3 THBS1 EGFR PCSK6

4.45e-04176904f25251abd4ef9fb077a978f9f9f658af58e4e0d2
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

SETD2 ZNF700 ZBTB3 ITGAV

4.45e-041769047a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGFR SCN3A RNF213 FGL2

4.54e-041779048dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGFR SCN3A RNF213 FGL2

4.54e-04177904767b2af5f224d100b22bed32f86cec1cd17e8711
ComputationalGenes in the cancer module 275.

ITGAV ITGB2 ITGB6

8.36e-0516593MODULE_275
DrugIndoprofen [31842-01-0]; Up 200; 14.2uM; PC3; HT_HG-U133A

PAPPA2 THBS1 HEG1 ZNF155 ZFP36L1 PCSK6 ZFHX2 IL6ST FGL2

8.74e-081979094249_UP
DrugCarbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A

PAPPA2 THBS1 ZNF652 KDM5C MAZ PCSK6 MTARC2 ZNF623

1.15e-061979083299_DN
DrugSulfaphenazole [526-08-9]; Up 200; 12.8uM; HL60; HT_HG-U133A

PAPPA2 ZNF668 ZFP36L1 DNAJA4 ZFHX2 MTARC2 POFUT1 FGL2

1.20e-061989081836_UP
DrugRgd Peptide

COL6A3 THBS1 ADGRB2 ADGRE1 ITGAV ITGB2 ITGB6 FGL2

4.85e-06239908CID000104802
DrugEthaverine hydrochloride [985-13-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A

SETD2 EGFR ZFP36L1 DNAJA4 PCSK6 POFUT1 IL6ST

1.12e-051929073375_DN
DrugMethazolamide [554-57-4]; Up 200; 17uM; MCF7; HT_HG-U133A

THBS1 EGFR ZNF652 MTARC2 ZNF350 ITGB6 IL6ST

1.16e-051939073474_UP
Drug0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A

ZFP36L1 LMO7 DNAJA4 KDM5C MAZ ADGRB2 ITGB2

1.20e-051949074331_DN
DrugSpiramycin [8025-81-8]; Down 200; 4.8uM; MCF7; HT_HG-U133A

ZNF652 KDM5C RALGAPB ZNF350 ZBTB3 MUL1 IL6ST

1.20e-051949073419_DN
DrugPhenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; MCF7; HT_HG-U133A

THBS1 PCSK6 POFUT1 ST18 ITGB2 MUL1 MYBPC3

1.24e-051959073217_UP
DrugMolindone hydrochloride [15622-65-8]; Up 200; 12.8uM; MCF7; HT_HG-U133A

PAPPA2 VLDLR DNAJA4 ADGRB2 ZNF571 POFUT1 IL6ST

1.29e-051969077337_UP
DrugThyroxine (L) [51-48-9]; Down 200; 5.2uM; HL60; HT_HG-U133A

SETD2 ZNF337 MAZ ZNF571 ZNF350 MUL1 ZMYM6

1.29e-051969071312_DN
DrugDiprophylline [479-18-5]; Up 200; 15.8uM; HL60; HT_HG-U133A

ZNF668 SETD2 HEG1 DNAJA4 POFUT1 MUL1 FGL2

1.33e-051979071853_UP
DrugRolitetracycline [751-97-3]; Up 200; 7.6uM; PC3; HT_HG-U133A

PAPPA2 VLDLR KDM5B ZNF155 ZFP36L1 SCN3A MYBPC3

1.42e-051999076731_UP
DrugAB-4

EGFR AFM GC

5.53e-0519903CID001367558
DrugEllipticine [519-23-3]; Down 200; 16.2uM; PC3; HT_HG-U133A

ZNF134 ZNF337 TRIM32 ZBTB3 ZNF623 MUL1

8.07e-051809065779_DN
DrugMitoxantrone dihydrochloride [70476-82-3]; Down 200; 7.8uM; MCF7; HT_HG-U133A

ZNF337 TRIM32 ZNF189 ZNF84 ZBTB3 ZNF623

8.84e-051839063232_DN
DrugChloroquine diphosphate [50-63-5]; Down 200; 7.8uM; MCF7; HT_HG-U133A

SETD2 THBS1 DNAJA4 ZFHX2 ZNF350 IL6ST

1.09e-041909062869_DN
Druggeldanamycin

VLDLR SETD2 THBS1 EGFR LMO7 OSBPL8 FRYL IL6ST

1.12e-04371908ctd:C001277
DrugPronethalol hydrochloride [51-02-5]; Down 200; 15uM; MCF7; HT_HG-U133A

ZNF134 SETD2 THBS1 ZFP36L1 IL6ST ZMYM6

1.15e-041929064104_DN
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; PC3; HT_HG-U133A

SETD2 THBS1 ZNF652 ZBTB3 ZNF623 IL6ST

1.15e-041929064274_DN
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

VLDLR THBS1 ZNF155 EGFR KDM5C IL6ST

1.18e-041939064343_DN
DrugClotrimazole [23593-75-1]; Up 200; 11.6uM; MCF7; HT_HG-U133A

VLDLR ZNF134 ZNF350 POFUT1 MUL1 IL6ST

1.18e-041939066207_UP
DrugSpurr resin

EGFR PCSK6 ITGAV ITGB6

1.21e-0464904CID006449895
DrugConessine [546-06-5]; Down 200; 11.2uM; MCF7; HT_HG-U133A

PRKD3 THBS1 ZFP36L1 PCSK6 POFUT1 IL6ST

1.22e-041949062792_DN
DrugCyclizine hydrochloride [303-25-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A

PAPPA2 ZNF134 DNAJA4 MAZ ZBTB3 MUL1

1.22e-041949062880_DN
DrugNadolol [42200-33-9]; Up 200; 13uM; MCF7; HT_HG-U133A

ZNF155 MAZ PCSK6 PPP1R13B ZNF350 ZNF623

1.22e-041949064139_UP
DrugMyosmine [532-12-7]; Up 200; 27.4uM; MCF7; HT_HG-U133A

THBS1 IMPG1 PCSK6 C6 ITGB6 MYBPC3

1.25e-041959063634_UP
DrugAlfadolone acetate [23930-37-2]; Down 200; 10.2uM; MCF7; HT_HG-U133A

PAPPA2 VLDLR SETD2 HEG1 EGFR KDM5C

1.29e-041969066506_DN
DrugMoricizine hydrochloride [31883-05-3]; Down 200; 8.6uM; PC3; HT_HG-U133A

ZNF668 HEG1 KDM5C ZNF350 ZNF84 IL6ST

1.29e-041969067297_DN
DrugEpirizole [18694-40-1]; Up 200; 17uM; MCF7; HT_HG-U133A

VLDLR ZNF134 ZFP36L1 MAZ ZNF350 MYBPC3

1.29e-041969061681_UP
DrugIopanoic acid [96-83-3]; Up 200; 7uM; PC3; HT_HG-U133A

PAPPA2 EGFR LMO7 DNAJA4 POFUT1 IL6ST

1.32e-041979066348_UP
Drug9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

PAPPA2 ZFHX2 ZNF350 POFUT1 MUL1 ZMYM6

1.32e-041979067500_UP
DrugAminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A

THBS1 HEG1 ZNF155 ZNF337 ADGRE1 MUL1

1.32e-041979063122_DN
DrugPapaverine hydrochloride [61-25-6]; Down 200; 10.6uM; MCF7; HT_HG-U133A

PRKD3 ZNF652 KDM5C POFUT1 MUL1 IL6ST

1.32e-041979062747_DN
DrugSpectinomycin dihydrochloride [21736-83-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A

SETD2 ZNF652 MAZ SKAP2 IL6ST LRP8

1.36e-041989064773_DN
DrugIdoxuridine [54-42-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A

SETD2 ZFP36L1 ZNF652 PCSK6 MTARC2 POFUT1

1.36e-041989064785_DN
DrugCefazolin sodium salt [27164-46-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A

SETD2 THBS1 ZNF652 ZNF189 POFUT1 MUL1

1.36e-041989063426_DN
DrugSulfabenzamide [127-71-9]; Down 200; 14.4uM; MCF7; HT_HG-U133A

DNAJA4 KDM5C MAZ ZNF350 POFUT1 IL6ST

1.36e-041989064979_DN
DrugEthynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A

PRKD3 ZNF571 MTARC2 ZNF623 SKAP2 ZMYM6

1.36e-041989064792_DN
DrugSulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A

PRKD3 THBS1 HEG1 PCSK6 ZNF350 POFUT1

1.36e-041989065622_DN
DrugViomycin sulfate [37883-00-4]; Up 200; 5.2uM; MCF7; HT_HG-U133A

ZNF134 SETD2 ZFP36L1 RALGAPB ADGRE1 IL6ST

1.40e-041999063541_UP
DrugLorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; MCF7; HT_HG-U133A

PAPPA2 ZNF134 KDM5C PCSK6 POFUT1 FGL2

1.40e-041999066456_UP
DrugChlormezanone [80-77-3]; Up 200; 14.6uM; MCF7; HT_HG-U133A

VLDLR KDM5B ZNF155 EGFR SCN3A ITGB2

1.40e-041999065697_UP
Drugpalladium

SP3 AFM ARX KDM5D

1.53e-0468904CID000023938
DrugAC1NE3ZI

GC KDM5D ITGB2 MYBPC3

1.62e-0469904CID004636205
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5B KDM5C KDM5D

8.88e-084843DOID:0060809 (implicated_via_orthology)
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5B KDM5C KDM5D

1.21e-0516843DOID:0050888 (implicated_via_orthology)
Diseaseexecutive function measurement, cognitive function measurement

ZNF613 ZNF350

4.79e-054842EFO_0008354, EFO_0009332
Diseaseintellectual disability (implicated_via_orthology)

KDM5B KDM5C KDM5D ITGAV

6.37e-0575844DOID:1059 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

KDM5B SH3RF2 KDM5C SCN1A KDM5D

7.55e-05152845DOID:0060041 (implicated_via_orthology)
DiseaseEPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 1

SCN1A ARX

1.19e-046842C3463992
Diseasecalcineurin subunit B type 1 measurement

PCSK6 C6

1.67e-047842EFO_0020215
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

KDM5C ARX

2.22e-048842C0796250
Diseasebipolar II disorder

SLIT1 ADGRE1

2.22e-048842EFO_0009964
DiseaseX-linked infantile spasms

SCN1A ARX

2.22e-048842C4552072
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN3A

3.55e-0410842DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN3A

3.55e-0410842DOID:0080422 (implicated_via_orthology)
Diseasedementia (is_implicated_in)

VLDLR LRP8

5.19e-0412842DOID:1307 (is_implicated_in)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN3A

5.19e-0412842DOID:0060170 (implicated_via_orthology)
Diseasecutaneous melanoma, hair color

ZFP36L1 LMO7 RREB1

7.46e-0462843EFO_0000389, EFO_0003924
Diseasehemorrhoid

XKR9 EGFR LMO7 ITGB6

8.38e-04147844EFO_0009552
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

VLDLR PCSK6

9.36e-0416842EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
DiseaseDermatitis

EGFR ITGB2

9.36e-0416842C0011603
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A ARX

9.36e-0416842C0393706
DiseaseSjogren's syndrome (implicated_via_orthology)

THBS1 MUC19

1.06e-0317842DOID:12894 (implicated_via_orthology)
Diseasemuscular dystrophy (is_implicated_in)

COL6A3 TRIM32

1.06e-0317842DOID:9884 (is_implicated_in)
Diseasecolorectal cancer (is_marker_for)

SETD2 THBS1 EGFR KDM5C

1.07e-03157844DOID:9256 (is_marker_for)
DiseaseIntellectual Disability

SETD2 KDM5C SCN1A SCN3A KMT2E ZMYM6

1.76e-03447846C3714756
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN3A

1.78e-0322842DOID:2030 (implicated_via_orthology)
Diseasecorpus collosum mid-posterior volume measurement

VLDLR EGFR

2.30e-0325842EFO_0010300
Diseasealcohol use disorder (implicated_via_orthology)

KDM5B EGFR KDM5C KDM5D

2.36e-03195844DOID:1574 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

SETD2 SCN1A KMT2E

2.40e-0393843C1535926
DiseaseHeart valve disease

C6 ITGB2

2.49e-0326842C0018824
Diseaseinflammatory biomarker measurement

VLDLR PCSK6

2.49e-0326842EFO_0004872

Protein segments in the cluster

PeptideGeneStartEntry
GEEVKPCSEKRCPAF

ADGRB2

516

O60241
SGKVCRKEVNECDLP

ADAM29

451

Q9UKF5
VVDKCCKAESPEVCF

AFM

576

P43652
IPFAGKVEVCCFDKT

ATP13A1

521

Q9HD20
FCSACKDKSVRIIDP

CORO1B

191

Q9BR76
KDRCESCSGAKVIRE

DNAJA4

191

Q8WW22
TTCRDVVEFCKEPGE

PPP1R13B

26

Q96KQ4
PTGLSKEDFAEVCKR

MMTAG2

91

Q9BU76
CKEIKDECPSAFDGL

ITLN1

41

Q8WWA0
CIGCKNFEESPERKT

LIN54

626

Q6MZP7
FRFDESGPESAKKVC

MTMR10

146

Q9NXD2
KNERTEEAECRCKPG

IMPG1

701

Q17R60
PDDERQCIKCKTTCF

KDM5D

691

Q9BY66
PEKCTVCKEGFSLAR

PCSK6

811

P29122
AREECVDKCKLAGAT

ITGB6

641

P18564
RGTCTDAKTIDCKPE

MUC19

8181

Q7Z5P9
ASRIAKVCAEEKCPT

FRYL

2126

O94915
RKDKDSGGESPCVSC

KMT2E

1276

Q8IZD2
KPEDRESLKSACVVC

MUL1

291

Q969V5
KRCASKVPRDCLGEV

PRKD3

311

O94806
CVFERTCPSKEKSNS

LMO7

611

Q8WWI1
STERPFKCEKCEAAF

MAZ

361

P56270
PDDERQCVKCKTTCF

KDM5B

686

Q9UGL1
FRAGSLCKRKSPECD

HEG1

1171

Q9ULI3
AKERGPSAAEVFKCV

KBTBD7

251

Q8WVZ9
CEIIERPSKKDGFCF

OSBPL8

196

Q9BZF1
PVKGRTCKERDSEGC

ITGB2

656

P05107
KGVSERESCNDPCKE

PAPPA2

746

Q9BXP8
ICEPFERKTSIVDCG

PAPPA2

1166

Q9BXP8
CRKFRDEATCKDTCP

EGFR

251

P00533
DCKAKRDTPTSCTVD

IL6ST

171

P40189
SDCDPCIEKQSKVRS

C6

91

P13671
CGEDNVCKPKLEVSV

ITGAV

626

P06756
ICKLPKDEGTCRDFI

COL6A3

3111

P12111
KSCKGVPVSEAECTA

MTARC2

66

Q969Z3
QEEGCSERPECKSKS

ARX

6

Q96QS3
KDVCPVRLESRGKCE

FGL2

36

Q14314
KDKSDEADCPLGTCR

LRP8

286

Q14114
CFEVAAQRSPDKKTC

POFUT1

126

Q9H488
CSAVRPKFVTCDAEG

TRIM32

511

Q13049
ICEGFENPCKDKIDT

TDRD6

1776

O60522
GKKDCCFEISAPDKR

SKAP2

181

O75563
GTSEKDRPCETCGKN

POLR3A

61

O14802
EDLKPEACFTEGCIK

SCN3A

1161

Q9NY46
EPEACFTEGCVQRFK

SCN1A

1176

P35498
IKTEGDKFIPCENRC

ST18

236

O60284
FKDPGVRCKDIDECS

ADGRE1

71

Q14246
KEETPKFCSQCGERL

RNF213

11

Q63HN8
EKPFLCIECGKSFSR

ZNF189

341

O75820
SPDGAVSDRKCKVCA

ZNF532

1256

Q9HCE3
KTELCRPFEENGACK

ZFP36L1

116

Q07352
CGFKCVIPVKELEEG

WFDC12

66

Q8WWY7
PEVKSCDSFVCAEVG

ZNF700

121

Q9H0M5
GEARETKACKKDACP

THBS1

476

P07996
ECPECGKAFREKSTV

ZNF182

291

P17025
EKPPQFVCRECKETF

ZNF668

511

Q96K58
TAATDKPFKCTVCRV

ZFHX2

1241

Q9C0A1
GRKPFECKECSAAFA

RREB1

786

Q92766
TGEKKFVCPECSKRF

SP3

676

Q02447
PKFGIEKEVRVCEPC

HGS

201

O14964
PGTAECCTKEGLERK

GC

106

P02774
PKEICALVGFCDEVK

PSAP

261

P07602
CRIFCSKKTGEEILP

RALGAPB

521

Q86X10
KPDCKVGRITTTEDF

SETD2

2491

Q9BYW2
EKPFACTECGKAFRR

ZNF517

421

Q6ZMY9
PFECRECGKAFSRKS

ZNF84

346

P51523
EKPFECSECGKAFST

ZNF350

371

Q9GZX5
RFSGVDKPFCSEVCK

ZMYM6

486

O95789
DKPFCSEVCKFLSAR

ZMYM6

491

O95789
GEKPFVCSECRKAFS

ZNF432

621

O94892
AREKCVGSVKLENPC

ZNF613

536

Q6PF04
TGEKPFRCDTCDKSF

ZNF155

311

Q12901
CKECGKTQSELRPSE

ZNF594

791

Q96JF6
ECPVCFEKLDVTAKV

SH3RF2

11

Q8TEC5
CPECGKAFSEKSRLR

ZNF782

396

Q6ZMW2
KPFTCEECGKIITSS

ZNF732

276

B4DXR9
RERPFECKECGKGFS

ZNF623

231

O75123
EKETLTCEKCPRVFN

ZNF652

241

Q9Y2D9
REAKPFECEECGKRF

ZNF275

176

Q9NSD4
EKPFDCEECGRSFKV

ZNF275

206

Q9NSD4
TSFAEEVEKPTKCGC

SLIT1

1516

O75093
PFECKECGKAFIRVA

ZNF571

446

Q7Z3V5
GEKPFECSECRKAFA

ZNF605

501

Q86T29
ECKECGKSFGDLVSR

ZNF317

391

Q96PQ6
PFVCSKCGKDFIRTS

ZNF134

371

P52741
EFCGKRFEKPDSVAA

ZNF692

451

Q9BU19
KCKEFVDSCRLTFPT

ZNF789

131

Q5FWF6
EKPFVCKDCERSFSQ

ZNF337

401

Q9Y3M9
TKCDEIDGKPVLREC

XKR9

351

Q5GH70
PGKFKCRSGECIDIS

VLDLR

321

P98155
VCKCKDRCEKEPSFT

WFIKKN2

131

Q8TEU8
VFTEDVPTCKTCGKT

ZBTB3

466

Q9H5J0
PDDERQCIKCKTTCF

KDM5C

701

P41229
CVVGGEKCSTELFVK

MYBPC3

436

Q14896