Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentprotein phosphatase 4 complex

PPP4R3B PPP4R3A

1.69e-046712GO:0030289
DomainSMK-1

PPP4R3B PPP4R3A

1.38e-052702PF04802
DomainDUF625

PPP4R3B PPP4R3A

1.38e-052702IPR006887
Pubmed

A PP4-phosphatase complex dephosphorylates gamma-H2AX generated during DNA replication.

PPP4R3B IGBP1 PPP4R3A

4.73e-07872318614045
Pubmed

Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.

PPP4R3B PPP4R3A

4.23e-06272216107728
Pubmed

The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair.

TLK2 TLK1

4.23e-06272221647934
Pubmed

PTEN expression contributes to the regulation of muscle protein degradation in diabetes.

PTEN LEPR

4.23e-06272217623817
Pubmed

Enhanced leptin-stimulated Pi3k activation in the CNS promotes white adipose tissue transdifferentiation.

PTEN LEPR

4.23e-06272218054313
Pubmed

Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres.

TLK2 TLK1

4.23e-06272232755577
Pubmed

cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.

TLK2 TLK1

4.23e-0627229427565
Pubmed

Hepatitis B virus X protein disrupts stress fiber formation and triggers apoptosis.

MYLK3 PTEN

4.23e-06272223591626
Pubmed

Deletion of Pten in pancreatic ß-cells protects against deficient ß-cell mass and function in mouse models of type 2 diabetes.

PTEN LEPR

4.23e-06272220852026
Pubmed

Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia.

MYC PTEN

4.23e-06272221527520
Pubmed

Differential requirements for c-Myc in chronic hematopoietic hyperplasia and acute hematopoietic malignancies in Pten-null mice.

MYC PTEN

4.23e-06272221926961
Pubmed

Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy.

MYC PTEN

4.23e-06272222281794
Pubmed

Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation.

MYC REST

4.23e-06272216478988
Pubmed

Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer.

MYC PTEN

4.23e-06272219578399
Pubmed

The coexistence of ERBB2, INT2, and CMYC oncogene amplifications and PTEN gene mutations in endometrial carcinoma.

MYC PTEN

4.23e-06272214663583
Pubmed

A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity.

PPP4R3B IGBP1 PPP4R3A

6.79e-061872316085932
Pubmed

PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.

PPP4R3B IGBP1 PPP4R3A

9.46e-062072318715871
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TYK2 ABCC4 TLK1 SHANK2 ANK3 SEPTIN5 ASH1L ARHGEF38 PHF6 QSER1 PTEN VPS13B SEPTIN6

1.04e-051489721328611215
Pubmed

A mouse model of heterogeneous, c-MYC-initiated prostate cancer with loss of Pten and p53.

MYC PTEN

1.27e-05372221685943
Pubmed

Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.

TLK2 TLK1

1.27e-05372228535374
Pubmed

MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors.

MYC PTEN

1.27e-05372221394210
Pubmed

MYC deficiency impairs the development of effector/memory T lymphocytes.

MYC PTEN

1.27e-05372234258568
Pubmed

Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer.

MYC PTEN

1.27e-05372226554830
Pubmed

Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma.

MYC PTEN

1.27e-05372219150964
Pubmed

SIRT1 promotes thyroid carcinogenesis driven by PTEN deficiency.

MYC PTEN

1.27e-05372222986535
Pubmed

Hypothalamic mTORC1 signaling controls sympathetic nerve activity and arterial pressure and mediates leptin effects.

PTEN LEPR

1.27e-05372223541372
Pubmed

Suppression of c-Myc is involved in multi-walled carbon nanotubes' down-regulation of ATP-binding cassette transporters in human colon adenocarcinoma cells.

MYC ABCC4

1.27e-05372225461681
Pubmed

Adipose-derived lipocalin 14 alleviates hyperglycaemia by suppressing both adipocyte glycerol efflux and hepatic gluconeogenesis in mice.

OBP2B LEPR

1.27e-05372226592241
Pubmed

Loss of phosphatase and tensin homolog (PTEN) induces leptin-mediated leptin gene expression: feed-forward loop operating in the lung.

PTEN LEPR

1.27e-05372223963458
Pubmed

MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase.

MYC PTEN

1.27e-05372223135913
Pubmed

mTORC1 and mTORC2 Kinase Signaling and Glucose Metabolism Drive Follicular Helper T Cell Differentiation.

MYC PTEN

1.27e-05372227637146
Pubmed

MiR-200c is a cMyc-activated miRNA that promotes nasopharyngeal carcinoma by downregulating PTEN.

MYC PTEN

1.27e-05372228029649
Pubmed

RapidCaP, a novel GEM model for metastatic prostate cancer analysis and therapy, reveals myc as a driver of Pten-mutant metastasis.

MYC PTEN

1.27e-05372224444712
Pubmed

c-Myc phosphorylation by PKCζ represses prostate tumorigenesis.

MYC PTEN

1.27e-05372223550155
Pubmed

FOXF2 aggravates the progression of non-small cell lung cancer through targeting lncRNA H19 to downregulate PTEN.

PTEN FOXF2

1.27e-05372231858547
Pubmed

MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer.

MYC PTEN

1.27e-05372237704631
Pubmed

Oncolytic Viruses Engineered to Enforce Leptin Expression Reprogram Tumor-Infiltrating T Cell Metabolism and Promote Tumor Clearance.

PTEN LEPR

1.27e-05372231471106
Pubmed

The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression.

TLK2 TLK1

1.27e-05372238498025
Pubmed

C-Myc negatively controls the tumor suppressor PTEN by upregulating miR-26a in glioblastoma multiforme cells.

MYC PTEN

1.27e-05372224140063
Pubmed

MicroRNA 152 regulates hepatic glycogenesis by targeting PTEN.

PTEN LEPR

1.27e-05372226996529
Pubmed

Overexpression of microRNA-26a protects against deficient β-cell function via targeting phosphatase with tensin homology in mouse models of type 2 diabetes.

PTEN LEPR

1.27e-05372229191656
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

MYC TLK1 IGBP1 PI4KA ASH1L PTEN

1.60e-0525772630945288
Pubmed

Targeting the MYC and PI3K pathways eliminates leukemia-initiating cells in T-cell acute lymphoblastic leukemia.

MYC PTEN

2.53e-05472225287161
Pubmed

Hunk negatively regulates c-myc to promote Akt-mediated cell survival and mammary tumorigenesis induced by loss of Pten.

MYC PTEN

2.53e-05472223520049
Pubmed

Mammalian homologues of the plant Tousled gene code for cell-cycle-regulated kinases with maximal activities linked to ongoing DNA replication.

TLK2 TLK1

2.53e-05472210523312
Pubmed

MYC-mediated miR-320a affects receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast formation by regulating phosphatase and tensin homolog (PTEN).

MYC PTEN

2.53e-05472234933640
Pubmed

Suppressor of MEK null (SMEK)/protein phosphatase 4 catalytic subunit (PP4C) is a key regulator of hepatic gluconeogenesis.

PPP4R3B PPP4R3A

2.53e-05472220876121
Pubmed

Pre-B cell receptor-mediated activation of BCL6 induces pre-B cell quiescence through transcriptional repression of MYC.

MYC PTEN

2.53e-05472221856866
Pubmed

Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours.

PTEN RFX2

2.53e-05472226690880
Pubmed

The c-Myc/miR17-92/PTEN Axis Tunes PI3K Activity to Control Expression of Recombination Activating Genes in Early B Cell Development.

MYC PTEN

2.53e-05472230524445
Pubmed

Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomics.

MYC PTEN

2.53e-05472225937169
Pubmed

Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity.

MYC PTEN

2.53e-05472238776224
Pubmed

Notch1 regulates PTEN expression to exacerbate renal tubulointerstitial fibrosis in diabetic nephropathy by inhibiting autophagy via interactions with Hes1.

PTEN LEPR

2.53e-05472229496446
Pubmed

Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells.

PPP4R3B PPP4R3A

2.53e-05472221423269
Pubmed

Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice.

PTEN LEPR

2.53e-05472221829168
Pubmed

Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases.

TLK2 TLK1

2.53e-05472211470414
Pubmed

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN.

PTEN LEPR

2.53e-05472219543271
Pubmed

Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine.

PTEN LEPR

2.53e-05472235649375
Pubmed

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.

COP1 LEPR

2.53e-05472217805301
Pubmed

Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal.

MYC PTEN

2.53e-05472231914399
Pubmed

Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases.

TLK2 TLK1

2.53e-05472220016786
Pubmed

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy.

MYC PTEN

4.21e-05572227111141
Pubmed

The cooperating mutation or "second hit" determines the immunologic visibility toward MYC-induced murine lymphomas.

MYC TYK2

4.21e-05572221878673
Pubmed

MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2.

MYC PTEN

4.21e-05572225829425
Pubmed

A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL).

PHF6 PTEN

4.21e-05572221642990
Pubmed

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation.

SEPTIN5 SEPTIN6

4.21e-05572224113571
Pubmed

β-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL.

MYC PTEN

4.21e-05572223801632
Pubmed

Tousled-like kinase in a microbial eukaryote regulates spindle assembly and S-phase progression by interacting with Aurora kinase and chromatin assembly factors.

TLK2 TLK1

4.21e-05572217940067
Pubmed

TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism.

COP1 LEPR

4.21e-05572216794074
Pubmed

CXCL12-Producing Vascular Endothelial Niches Control Acute T Cell Leukemia Maintenance.

MYC LEPR

6.31e-05672226058075
Pubmed

Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.

PTEN LEPR

6.31e-05672224953181
Pubmed

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.

MYC PTEN

6.31e-05672228003334
Pubmed

Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.

TLK2 TLK1

6.31e-05672212660173
Pubmed

Comparative characteristics of genetic aberrations in glioblastomas in children and adults.

MYC PTEN

6.31e-05672225033601
Pubmed

A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy.

MYC PTEN

6.31e-05672223908595
Pubmed

Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.

MYC PTEN

6.31e-05672220729907
Pubmed

Differential localization of septins in the mouse brain.

SEPTIN5 SEPTIN6

8.82e-05772211064363
Pubmed

The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice.

MYC ASH1L

8.82e-05772228374742
Pubmed

FoxF1 and FoxF2 transcription factors synergistically promote rhabdomyosarcoma carcinogenesis by repressing transcription of p21Cip1 CDK inhibitor.

MYC FOXF2

1.17e-04872227425595
Pubmed

Discrete roles and bifurcation of PTEN signaling and mTORC1-mediated anabolic metabolism underlie IL-7-driven B lymphopoiesis.

MYC PTEN

1.17e-04872229399633
Pubmed

COP1 is a tumour suppressor that causes degradation of ETS transcription factors.

COP1 PTEN

1.17e-04872221572435
Pubmed

Genetic heterogeneity in colorectal cancer associations between African and European americans.

MYC RHPN2

1.51e-04972220659471
Pubmed

Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis.

C2CD3 MIB1

1.51e-04972227146717
Pubmed

Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis.

PPP4R3B PPP4R3A

1.51e-04972228467410
Pubmed

Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission.

SEPTIN5 SEPTIN6

1.51e-04972218809578
Pubmed

Ku80 binds to human replication origins prior to the assembly of the ORC complex.

MYC ORC3

1.88e-041072215910003
Pubmed

Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell Carcinoma.

MYC PTEN

2.30e-041172226063791
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

SHANK2 PTEN

2.30e-041172226403076
Pubmed

Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis.

PPP4R3B PPP4R3A

2.75e-041272229180410
Pubmed

Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells.

MYC TYK2

2.75e-041272212637327
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

PPP4R3B RTL9 MIB1 ASH1L

2.94e-0415372410718198
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

SHANK2 PTEN

3.25e-041372227050589
Pubmed

Identification of novel oocyte and granulosa cell markers.

ZFP69 LRRC17

3.25e-041372219539053
Pubmed

β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma.

MYC PTEN

3.78e-041472223300485
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

IGBP1 C2CD3 PI4KA PIP4K2A MIB1 QPCT PHF6

3.79e-0464572725281560
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TLK2 ANK3 PI4KA ASH1L TMEM254 QSER1 VPS13B SEPTIN6 LRRC17

3.93e-04108472911544199
Pubmed

Localization of septin proteins in the mouse cochlea.

SEPTIN5 SEPTIN6

4.98e-041672222575789
Pubmed

Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.

MYC RHPN2

5.63e-041772224737748
Pubmed

Differential requirements for Tousled-like kinases 1 and 2 in mammalian development.

TLK2 TLK1

5.63e-041772228708136
Pubmed

PTEN Regulates Glucose Transporter Recycling by Impairing SNX27 Retromer Assembly.

IPO4 PTEN

5.63e-041772229117568
Cytoband19q13.41

ZNF611 ZNF816 ZNF702P

2.59e-047872319q13.41
GeneFamilySeptins

SEPTIN5 SEPTIN6

5.28e-0413482732
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_500

TLK2 MIB1 ASH1L GAN CLSTN2 PTEN

2.21e-05172706gudmap_developingGonad_e11.5_ovary + mesonephros_k4_500
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 ANK3 BAIAP2L1 RHPN2 ARHGEF38 CHST9

8.06e-07200716d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

CCNJL ABCC4 SHANK2 ANK3 ARHGEF38

6.30e-06163715e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1 CLSTN2

9.92e-06179715fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1 CLSTN2

1.05e-051817150513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1 CLSTN2

1.10e-05183715e972432dd4d1bd31bb0982f4df3061e5e152658f
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1 CLSTN2

1.13e-05184715ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

CCNJL SHANK2 ANK3 BAIAP2L1 ARHGEF38

1.16e-05185715cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1 CLSTN2

1.26e-051887154bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SNED1 MXRA8 FAXDC2 CLSTN2 LEPR

1.29e-05189715d531399749409d614adca13d181830c6e3287508
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SNED1 MAB21L3 MXRA8 NDP FOXF2

1.29e-051897153169476f98b7385706cb618c9ad64ae83a290ef0
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

SHANK2 ANK3 BAIAP2L1 ARHGEF38 CHST9

1.32e-0519071551ca9ef4df3220487152fcf684147730637c7cc1
ToppCellCOVID-19-lung-Secretory|COVID-19 / Disease (COVID-19 only), tissue and cell type

SHANK2 ANK3 BAIAP2L1 ARHGEF38 CHST9

1.39e-0519271559261098ccb52306f837f632ebaea45b90ad30fe
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SNED1 SHANK2 ANK3 CLSTN2 NDP

1.46e-0519471569362e13158033de44f90f3773db6c0f27de8cb3
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CCNJL ABCC4 SHANK2 ANK3 ARHGEF38

1.46e-0519471597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell10x3'2.3-week_12-13-Hematopoietic|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MYC ABCC4 ART4 FAXDC2 RFESD

1.54e-0519671505b437af66cb43ba098ea93a02dc2f7430bf8c1b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SHANK2 ANK3 BAIAP2L1 RHPN2 ARHGEF38

1.58e-051977157e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TLK2 ANK3 ASH1L DEGS2 VPS13B

1.65e-05199715f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SNED1 QPCT DEGS2 LEPR FOXF2

1.65e-05199715236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCellBronchial-10x5prime-Epithelial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ANK3 BAIAP2L1 ARHGEF38 CHST9 DEGS2

1.69e-05200715d3ee5f79513e2ac02ad3329b59e6290d457c44d2
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SHANK2 ANK3 RHPN2 ARHGEF38 CHST9

1.69e-052007150eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MAB21L3 ARHGEF38 IPO4 F12

4.63e-05124714d88bce8a4f023d5b617b2e8e372a94bd1248d20d
ToppCellPND01-03-samps-Mesenchymal-Pericyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

AMPD1 ADRA1A CLSTN2 LEPR

1.02e-04152714fc9472bc19f997103da535b035105f01429cb08e
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYC ADRA1A ART4 MXRA8

1.07e-0415471444d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

CCNJL ABCC4 ANK3 ARHGEF38

1.16e-0415771431d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MAB21L3 SHANK2 ANK3 ARHGEF38

1.30e-041627145c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYC RHPN2 CHST9 DEGS2

1.37e-041647148d1d0424943d3e98c8b6399dbf702e0035d0db7b
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 ARHGEF38 CHST9 DEGS2

1.43e-041667141df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 ARHGEF38 CHST9 DEGS2

1.43e-041667149628522e7af8f8edca733588a364ab2454ac5ca5
ToppCellControl|World / group, cell type (main and fine annotations)

SHANK2 ANK3 BAIAP2L1 RFX2

1.50e-04168714a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Red_blood_cells|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYBA4 ART4 FAXDC2 RFESD

1.72e-04174714001254db9f4c346d06d31a7fa1213498f92e4280
ToppCell5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CRYBA4 ART4 FAXDC2 RFESD

1.72e-04174714ce2bc1797707c3f48ef551de7edbfd7b47e5a36e
ToppCellCOVID-19-lung-RBC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ABCC4 ART4 PIP4K2A ZFPM1

1.75e-041757144c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCellpdx-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SHANK2 MARK4 FAXDC2 CHST9

1.79e-041767141e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCellCOPD-Lymphoid-ILC_A|COPD / Disease state, Lineage and Cell class

CCNJL PIP4K2A ZNF611 ZFPM1

1.79e-04176714484452cb38fe4604f0910a068361ed461b5b0c21
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

CCNJL ABCC4 SHANK2 ARHGEF38

1.79e-041767143fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCC4 SHANK2 ANK3 ARHGEF38

1.79e-041767143bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PLEKHM2 PIP4K2A MARK4 ATL1

1.83e-0417771468f1139fc378f351e3b9e9f392aacb150025bf03
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_Tfh|T/NK_cells / Location, Cell class and cell subclass

HINFP ZNF780B MARK4 QSER1

1.87e-041787149a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 SHANK2 ANK3 ARHGEF38

1.87e-04178714f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nnat_(Neuron.Slc17a6.Nnat)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAB21L3 MYLK3 CHST9

1.91e-0470713df81f7c1d901eb34b82f564ee15c10a0f4dd153f
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nnat_(Neuron.Slc17a6.Nnat)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MAB21L3 MYLK3 CHST9

1.91e-04707132895c9fa3b2c1fadbcfef7814ee4ce8cc5e76cfd
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ART4 PI4KA MXRA8 ZFP69

1.91e-04179714ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellLV|World / Chamber and Cluster_Paper

ADRA1A MYLK3 CHST9 RNF207

1.95e-041807145ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 ANK3 BAIAP2L1 CLSTN2

1.95e-04180714b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCNJL ABCC4 SHANK2 ANK3

1.99e-04181714576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYC PPP4R3B ANK3 PPP4R3A

2.04e-041827141aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A ART4 MXRA8 FOXF2

2.04e-04182714c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A ART4 MXRA8 FOXF2

2.04e-04182714dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYC PPP4R3B ANK3 PPP4R3A

2.04e-04182714b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYC PPP4R3B ANK3 PPP4R3A

2.04e-04182714c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYC PPP4R3B ANK3 PPP4R3A

2.04e-041827144cb182ef39be2044a6ad7266f332d4177591e550
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Mild / Disease group, lineage and cell class

MYC PPP4R3B ANK3 PPP4R3A

2.08e-041837147717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MYC ART4 FAXDC2 RFESD

2.12e-041847140efc757d9512d6a8fe8176e977a94e4494ed9778
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SHANK2 ARHGEF38 CHST9 DEGS2

2.12e-04184714fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

ART4 CLSTN2 PTEN LEPR

2.12e-0418471467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

ABCC4 SHANK2 ANK3 ARHGEF38

2.17e-04185714673f0c688ae6984bc8027df2da335787924f4137
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 SHANK2 ANK3 ARHGEF38

2.17e-0418571498b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1

2.17e-04185714fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1

2.17e-04185714929b68b05b7686341329ac756d7df172cb4b810b
ToppCellfacs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TYK2 PIP4K2A QPCT SEPTIN6

2.17e-04185714ed7b26bdebfd0df2b4f5020a855a052d94ae7219
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCNJL ABCC4 ANK3 ARHGEF38

2.21e-04186714acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1

2.21e-04186714e83718fabb057100835d3357df407f283d23fe16
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYC MXRA8 CLSTN2 RFX2

2.21e-041867147582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 ART4 MXRA8 CLSTN2

2.26e-04187714b6ecf55014f246461bf1ca12f24cb4d046661fa4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal-hepatic_stellate_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 ART4 MXRA8 CLSTN2

2.26e-041877149fb15f24b9b364b0c4704ec98aec236eaec5411c
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

ABCC4 SHANK2 ANK3 ARHGEF38

2.26e-0418771481cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

ABCC4 BAIAP2L1 ARHGEF38 IPO4

2.26e-04187714fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCelldroplet-Liver-HEPATOCYTES-1m-Mesenchymal|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANK3 ART4 MXRA8 CLSTN2

2.26e-04187714e6afbaed352310a1cb49571a2aae18be1f533c9a
ToppCellTCGA-Prostate-Primary_Tumor|TCGA-Prostate / Sample_Type by Project: Shred V9

ABCC4 BAIAP2L1 ARHGEF38 IPO4

2.26e-041877143e6a95c912dad5d61e10497ffaafd2b9027cd13a
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ANK3 ORC3 MXRA8 ASH1L

2.31e-04188714b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCC4 SHANK2 ANK3 BAIAP2L1

2.31e-0418871443a0508d2524a5b310e89e9422843dcaab999bc3
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

ADRA1A MYLK3 CHST9 RNF207

2.31e-041887140758b474457efa36488e0195f7357100f4b6a090
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

SHANK2 ANK3 BAIAP2L1 ARHGEF38

2.31e-04188714c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

SHANK2 ANK3 BAIAP2L1 ARHGEF38

2.31e-04188714707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellRV-06._Ventricular_Cardiomyocyte_II|World / Chamber and Cluster_Paper

ADRA1A MYLK3 CHST9 RNF207

2.35e-041897145e80c47f63980904c4c1ff02c201b67b456a0974
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYC TLK1 ANK3 SEPTIN6

2.35e-041897148130102c41b2978a8b83f765ce383f836a464795
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.35e-0418971440cbd679dc0548bf5207e1b033c0597886ad6fe1
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

SHANK2 ANK3 ARHGEF38 CHST9

2.35e-0418971484d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A ART4 MXRA8 FOXF2

2.35e-04189714324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MXRA8 CLSTN2 LEPR FOXF2

2.35e-04189714ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A ART4 MXRA8 FOXF2

2.40e-0419071400fd993675faf53adf985b9316a18c8a33242029
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CLSTN2 PTEN LEPR FOXF2

2.40e-04190714979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA1A ART4 MXRA8 FOXF2

2.40e-041907148cda09d761c6b504a744959d587c183f94f1beeb
ToppCellP07-Mesenchymal-developing_mesenchymal_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CLSTN2 PTEN LEPR FOXF2

2.45e-04191714ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-0419171436467322096bc766cd777dae3bfb4e65511e492c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SNED1 ART4 CLSTN2 FOXF2

2.45e-04191714a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellfacs-MAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ART4 MXRA8 QPCT LEPR

2.45e-04191714b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCC4 SHANK2 ANK3 ARHGEF38

2.45e-04191714a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-04191714094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-04191714beb5bb42bd53bce01339da9110d374901548793c
ToppCelldroplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-0419171494795daf05061baa3b72a1b01c9e940af86de044
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-041917146609d85fd2577633dcc067507304a6f9e5865ca3
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

CCNJL SHANK2 ANK3 ARHGEF38

2.45e-04191714276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-04191714c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCellfacs-Lung-24m-Mesenchymal|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-04191714ba02cbdfda6a94374a6472eb88499059979af472
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-0419171480484d39f34703a33b9bac09826b7a526e883cab
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-04191714243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-04191714d4f535b06ad483448ab692e9900c872c78cbed60
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-041917145c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADRA1A ART4 MXRA8 FOXF2

2.45e-04191714b5210de890d338602857b5907135705a507bc2b0
DrugEburnamonine (-) [4880-88-0]; Down 200; 13.6uM; PC3; HT_HG-U133A

CCNJL PLEKHM2 MARK4 FAXDC2 REST VPS13B SEPTIN6

2.14e-061907177154_DN
Drug2,3,6-trichloroanisole

MIB1 QPCT

9.59e-062712CID000039656
Drugms37

TLK2 TLK1

9.59e-062712CID016122503
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

MYC PPP4R3B TLK1 REST F12 PPP4R3A

1.42e-051687166820_DN
Diseaseplatelet measurement

ABCC4 SEPTIN5 MARK4 REST F12 ARPC2

9.62e-05315696EFO_0005036
Diseaseimmature platelet measurement

TLK1 SEPTIN5 MARK4 ARPC2

1.78e-04119694EFO_0803541
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

MYC TYK2 PHF6

2.64e-0453693C1961099
DiseaseDuctal Carcinoma

MYC PTEN

2.92e-0411692C1176475
Diseaserenal cell carcinoma (biomarker_via_orthology)

MYC PTEN

4.82e-0414692DOID:4450 (biomarker_via_orthology)
DiseaseLeft ventricular noncompaction

PLEKHM2 MIB1

4.82e-0414692C1960469
DiseaseTinnitus, response to cisplatin

ADRA1A PIP4K2A

5.55e-0415692GO_0072718, HP_0000360
Diseasecalcium measurement

HINFP ABCC4 RTL9 MARK4 QPCT ZFPM1 ATL1

6.59e-04628697EFO_0004838
DiseaseFetal Alcohol Syndrome

ANK3 REST

7.16e-0417692C0015923
Diseasediastolic blood pressure, systolic blood pressure

PPP4R3B C2CD3 ANK3 OBP2B PIP4K2A PTEN F12

9.62e-04670697EFO_0006335, EFO_0006336
DiseaseAdenocarcinoma of prostate

MYC PTEN

9.96e-0420692C0007112
DiseaseFatty Liver

MYC PTEN LEPR

1.16e-0388693C0015695
DiseaseSteatohepatitis

MYC PTEN LEPR

1.16e-0388693C2711227
DiseaseColorectal Carcinoma

MYC AMPD1 ABCC4 MYLK3 RHPN2 CLSTN2 PTEN

1.26e-03702697C0009402
DiseaseAdenocarcinoma of large intestine

TYK2 MARK4 PTEN

1.50e-0396693C1319315
DiseaseAcute kidney injury

SEPTIN5 ATL1

1.56e-0325692HP_0001919
Diseaseplatelet-to-lymphocyte ratio

TYK2 ABCC4 MARK4 ZFPM1 ARPC2

1.62e-03363695EFO_0008446
Diseasecongestive heart failure (is_implicated_in)

AMPD1 PHF6

1.82e-0327692DOID:6000 (is_implicated_in)
Diseaseimmature platelet count

TLK1 MARK4 ARPC2

1.99e-03106693EFO_0803544

Protein segments in the cluster

PeptideGeneStartEntry
ADHCVHYYDLRNTKQ

COP1

576

Q8NHY2
QYHNHSDHYCLNLDS

ASH1L

2191

Q9NR48
VACHRHLHSVTHYYI

ADRA1A

51

P35348
EDIYKIYCYHHDEAH

ARHGEF38

181

Q9NXL2
LHYHIKCSKAYIHTR

ARPC2

251

O15144
YYLLASVSQKDHHCH

CCNJL

201

Q8IV13
HRDFYNCRKVDTHIH

AMPD1

291

P23109
RHHYALYVHNCRLVF

CLSTN2

411

Q9H4D0
AKRHLVLACHYDSKY

QPCT

131

Q16769
HHYKYHVYLICKDEI

QSER1

1676

Q2KHR3
LTFCVEHHTYHIKNY

PPP4R3A

516

Q6IN85
NRYDHYTAHLKHHTR

REST

226

Q13127
SHICLHDYREVYREH

NLRP10

91

Q86W26
SLHKDHYENLYCVVS

JMJD7

176

P0C870
KHHYNVHFNGLECKT

LRRC17

366

Q8N6Y2
REHFINYLTQCHCYH

IGBP1

106

P78318
KRFQYCHSHVLAHAY

OR51G1

166

Q8NGK1
CEGVHYLHQHYILHL

MYLK3

621

Q32MK0
AHKKYYCSSHAAEHV

ZFPM1

991

Q8IX07
DYKDHGYRHCSLAVI

PI4KA

696

P42356
HECHHRYAELYVIDV

LEPR

416

P48357
LTFCVEHHTYHIKNY

PPP4R3B

551

Q5MIZ7
HPLYKDQACYIFHHR

MRPL37

96

Q9BZE1
HKGEYHAMDIRCYHS

RFESD

46

Q8TAC1
HKCVSQHFLKHYFVR

MAB21L3

316

Q8N8X9
YDLCTVCYHGDKHHL

MIB1

106

Q86YT6
VCYHGDKHHLRHRFY

MIB1

111

Q86YT6
LHHLYFYHVQCAGMR

ABCC4

151

O15439
RRDHYIFYCKDQHHG

OBP2B

106

Q9NPH6
HDYHHLKFNQCYGVL

FAXDC2

276

Q96IV6
KLYSAAATHRHLYHQ

ATL1

526

Q8WXF7
LVDKHCGFANHIHYY

BAIAP2L1

196

Q9UHR4
HNHIHKNTYCYLRYK

C2CD3

1426

Q4AC94
ALHYCLHHVHYLATE

GAN

141

Q9H2C0
AASFKKYHVDHHRYL

DEGS2

121

Q6QHC5
DYLTALHVAAHCGHY

ANK3

366

Q12955
QYVLECDHHSGDYKH

CRYBA4

161

P53673
VSAVHYCHQKNIVHR

MARK4

166

Q96L34
DLIRHVYFHCYHTKL

HINFP

81

Q9BQA5
HTHHLAKACYALENF

IPO4

451

Q8TEX9
HNILKKYHQYIVECH

PIP4K2A

156

P48426
HKNHYKIYNLCAERH

PTEN

61

P60484
HVYHMNYFLVLRCLH

ORC3

406

Q9UBD5
HKYYVKNALVCSHDH

PLEKHM2

121

Q8IWE5
SYYHHHHQSVCQDIK

FOXF2

426

Q12947
FQYHRQLYHKCTHKG

F12

51

P00748
QTEEHQHVSKRCYYL

RTL9

1346

Q8NET4
AEHCRHYEDSYRHLQ

RNF207

421

Q6ZRF8
KDVTCDVHYENYRAH

SEPTIN5

296

Q99719
YNHYLRHCQEHKLDP

RFX2

221

P48378
VLKRCHVSTHQHNYA

MYC

296

P01106
CVKAHHYAALAHYFT

RHPN2

346

Q8IUC4
HTYHDSRIHVCLYFI

SEPTIN6

141

Q14141
CHHVYKRVYRVHQDI

SNED1

1371

Q8TER0
CRYGHVQHLEHLLFY

SHANK2

306

Q9UPX8
NYHKHACREYRIHKE

TLK2

506

Q86UE8
AYNISHNAVHYGKHL

CHST9

241

Q7L1S5
TYDHLCKNCHHVIAR

CHURC1

56

Q8WUH1
YHKHACREYRIHKEL

TLK1

501

Q9UKI8
VKTCHRTYHYHCALH

PHF6

96

Q8IWS0
RTYHYHCALHDKAQI

PHF6

101

Q8IWS0
LHLLLECYIQYHHSK

TMEM192

106

Q8IY95
KRYLAYHHRCHTGEK

ZNF702P

46

Q9H963
CVKAHHYTALAHYFT

RHPN2P1

261

A8MT19
YHYQLIEHCRIHTGE

ZNF780B

316

Q9Y6R6
RHHYVDSISHPLYKC

NDP

41

Q00604
HHELYHQISSYPDCK

VPS13B

3291

Q7Z7G8
AFACHSYLAKHTRIH

ZNF611

546

Q8N823
QYLVDHHHTLLCNGY

TMEM254

51

Q8TBM7
YIVYHHRCHTGEKTY

ZNF816

271

Q0VGE8
MAYLHAQHYIHRDLA

TYK2

1011

P29597
CCKTFSHRAYLTHHQ

ZFP69

416

Q49AA0
LCYEVHYRTKDVHFN

ART4

181

Q93070
TCNLHHHYCHLYESL

MXRA8

136

Q9BRK3
HHYCHLYESLAVRLE

MXRA8

141

Q9BRK3