Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR3	8.54e-05	4	76	2	GO:0005219
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR3	2.12e-04	6	76	2	GO:0048763
GeneOntologyCellularComponent	microbody	SZT2 CD33 PEX6 ACOT6 ACOT4	3.52e-04	162	78	5	GO:0042579
GeneOntologyCellularComponent	peroxisome	SZT2 CD33 PEX6 ACOT6 ACOT4	3.52e-04	162	78	5	GO:0005777
GeneOntologyCellularComponent	supramolecular polymer	COL4A2 RGS14 MAPT RTL1 DNAH17 TOGARAM2 MYO18A NAV1 ABLIM2 RYR1 RYR3 AHNAK2 NPNT	4.19e-04	1187	78	13	GO:0099081
GeneOntologyCellularComponent	junctional membrane complex	RYR1 RYR3	4.86e-04	9	78	2	GO:0030314
GeneOntologyCellularComponent	contractile muscle fiber	RTL1 ABLIM2 RYR1 RYR3 AHNAK2 NPNT	7.53e-04	290	78	6	GO:0043292
Domain	Ryanrecept_TM4-6	RYR1 RYR3	4.89e-05	3	76	2	IPR009460
Domain	RyR	RYR1 RYR3	4.89e-05	3	76	2	PF02026
Domain	Ryanodine_rcpt	RYR1 RYR3	4.89e-05	3	76	2	IPR003032
Domain	RR_TM4-6	RYR1 RYR3	4.89e-05	3	76	2	PF06459
Domain	Ryan_recept	RYR1 RYR3	4.89e-05	3	76	2	IPR013333
Domain	BAAT_C	ACOT6 ACOT4	1.62e-04	5	76	2	IPR014940
Domain	BAAT_C	ACOT6 ACOT4	1.62e-04	5	76	2	PF08840
Domain	RIH_assoc	RYR1 RYR3	2.43e-04	6	76	2	PF08454
Domain	RIH_assoc-dom	RYR1 RYR3	2.43e-04	6	76	2	IPR013662
Domain	RIH_dom	RYR1 RYR3	2.43e-04	6	76	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR3	2.43e-04	6	76	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR3	2.43e-04	6	76	2	IPR015925
Domain	-	RYR1 RYR3	2.43e-04	6	76	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR3	2.43e-04	6	76	2	PF01365
Domain	Ins145_P3_rec	RYR1 RYR3	2.43e-04	6	76	2	PF08709
Domain	ConA-like_dom	CELSR3 CELSR2 NBEAL2 RYR1 RYR3 NPNT	2.68e-04	219	76	6	IPR013320
Domain	MIR	RYR1 RYR3	7.20e-04	10	76	2	PS50919
Domain	MIR	RYR1 RYR3	7.20e-04	10	76	2	PF02815
Domain	MIR	RYR1 RYR3	7.20e-04	10	76	2	SM00472
Domain	MIR_motif	RYR1 RYR3	7.20e-04	10	76	2	IPR016093
Domain	ASX_HYDROXYL	CELSR3 CELSR2 HMCN1 NPNT	7.39e-04	100	76	4	PS00010
Domain	GAIN_dom_N	CELSR3 CELSR2	8.78e-04	11	76	2	IPR032471
Domain	GAIN	CELSR3 CELSR2	8.78e-04	11	76	2	PF16489
Domain	EGF-type_Asp/Asn_hydroxyl_site	CELSR3 CELSR2 HMCN1 NPNT	9.19e-04	106	76	4	IPR000152
Domain	EGF_CA	CELSR3 CELSR2 HMCN1 NPNT	1.55e-03	122	76	4	SM00179
Domain	EGF-like_Ca-bd_dom	CELSR3 CELSR2 HMCN1 NPNT	1.64e-03	124	76	4	IPR001881
Domain	EGF	CELSR3 CELSR2 HMCN1 ITGB5	1.74e-03	126	76	4	PF00008
Domain	DH_1	PLEKHG4B PREX2 SOS1	2.16e-03	63	76	3	PS00741
Domain	PDZ	FRMPD4 MYO18A PREX2 AHNAK2	2.62e-03	141	76	4	PF00595
Domain	RhoGEF	PLEKHG4B PREX2 SOS1	2.68e-03	68	76	3	SM00325
Domain	EGF	CELSR3 CELSR2 HMCN1 ITGB5 NPNT	2.70e-03	235	76	5	SM00181
Domain	AAA+_ATPase	IGHMBP2 NAV1 PEX6 RNF213	2.83e-03	144	76	4	IPR003593
Domain	AAA	IGHMBP2 NAV1 PEX6 RNF213	2.83e-03	144	76	4	SM00382
Domain	RhoGEF	PLEKHG4B PREX2 SOS1	2.91e-03	70	76	3	PF00621
Domain	DH_2	PLEKHG4B PREX2 SOS1	2.91e-03	70	76	3	PS50010
Domain	DH-domain	PLEKHG4B PREX2 SOS1	3.03e-03	71	76	3	IPR000219
Domain	-	PLEKHG4B PREX2 SOS1	3.03e-03	71	76	3	1.20.900.10
Domain	PDZ	FRMPD4 MYO18A PREX2 AHNAK2	3.12e-03	148	76	4	SM00228
Domain	-	FRMPD4 MYO18A PREX2 AHNAK2	3.28e-03	150	76	4	2.30.42.10
Domain	PDZ	FRMPD4 MYO18A PREX2 AHNAK2	3.36e-03	151	76	4	PS50106
Domain	-	HMCN1 ITIH6 ITGB5	3.41e-03	74	76	3	3.40.50.410
Domain	PDZ	FRMPD4 MYO18A PREX2 AHNAK2	3.44e-03	152	76	4	IPR001478
Domain	Growth_fac_rcpt_	ERBB3 CELSR2 HMCN1 NPNT	3.77e-03	156	76	4	IPR009030
Domain	EGF_1	CELSR3 CELSR2 HMCN1 ITGB5 NPNT	3.83e-03	255	76	5	PS00022
Domain	EGF-like_CS	CELSR3 CELSR2 HMCN1 ITGB5 NPNT	4.23e-03	261	76	5	IPR013032
Domain	EGF_2	CELSR3 CELSR2 HMCN1 ITGB5 NPNT	4.51e-03	265	76	5	PS01186
Domain	VWFA	HMCN1 ITIH6 ITGB5	4.55e-03	82	76	3	PS50234
Domain	HormR	CELSR3 CELSR2	4.61e-03	25	76	2	SM00008
Domain	VWA	HMCN1 ITIH6 ITGB5	4.87e-03	84	76	3	SM00327
Domain	ARM-like	NBEAL2 TOGARAM2 HMGB1 CTNND1 BRAT1	4.88e-03	270	76	5	IPR011989
Domain	SANT_dom	NCOR2 MIER1	4.99e-03	26	76	2	IPR017884
Domain	SANT	NCOR2 MIER1	5.77e-03	28	76	2	PS51293
Domain	HRM	CELSR3 CELSR2	5.77e-03	28	76	2	PF02793
Domain	EGF_LAM_2	CELSR3 CELSR2	6.60e-03	30	76	2	PS50027
Domain	EGF_LAM_1	CELSR3 CELSR2	6.60e-03	30	76	2	PS01248
Domain	VWF_A	HMCN1 ITIH6 ITGB5	7.68e-03	99	76	3	IPR002035
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PLEKHG4B NCOR2 ITCH MAPT NAV1 RNF213 PISD ZNF362 CTNND1 ALDH3B2 ABLIM2 UBN2 ITGB5 RXRA DOP1A	1.58e-06	1489	81	15	28611215
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOR2 WIZ CELSR3 CELSR2 SZT2 NBEAL2 NAV1 PEX6 ZC3H7B BRAT1 ITGB5 RYR1 AHNAK2	1.59e-06	1105	81	13	35748872
Pubmed	Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.	RYR1 RYR3	5.36e-06	2	81	2	12565913
Pubmed	Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.	RYR1 RYR3	5.36e-06	2	81	2	9489997
Pubmed	Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.	RYR1 RYR3	5.36e-06	2	81	2	9192302
Pubmed	The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.	RYR1 RYR3	5.36e-06	2	81	2	12640042
Pubmed	Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on chromosome 9.	CELSR3 CELSR2	5.36e-06	2	81	2	10790539
Pubmed	Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.	RYR1 RYR3	5.36e-06	2	81	2	7556644
Pubmed	Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.	RYR1 RYR3	5.36e-06	2	81	2	14592949
Pubmed	Interactions that determine the assembly of a retinoid X receptor/corepressor complex.	NCOR2 RXRA	5.36e-06	2	81	2	11972046
Pubmed	Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.	RYR1 RYR3	5.36e-06	2	81	2	15894801
Pubmed	Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.	RYR1 RYR3	5.36e-06	2	81	2	9799464
Pubmed	Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.	RYR1 RYR3	5.36e-06	2	81	2	9817784
Pubmed	Nuclear Inhibitor of Protein Phosphatase 1 (NIPP1) Regulates CNS Tau Phosphorylation and Myelination During Development.	PPP1R8 MAPT	5.36e-06	2	81	2	36198882
Pubmed	Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer's disease and frontotemporal dementia.	MAPT HMGB1	5.36e-06	2	81	2	34289368
Pubmed	Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.	RYR1 RYR3	5.36e-06	2	81	2	17118445
Pubmed	RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.	RYR1 RYR3	5.36e-06	2	81	2	11500519
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR3	1.60e-05	3	81	2	18403125
Pubmed	Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.	RYR1 RYR3	1.60e-05	3	81	2	11171121
Pubmed	Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.	RYR1 RYR3	1.60e-05	3	81	2	18313230
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR3	1.60e-05	3	81	2	18434746
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR3	1.60e-05	3	81	2	9204703
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR3	1.60e-05	3	81	2	7876312
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR3	1.60e-05	3	81	2	21881589
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR3	1.60e-05	3	81	2	12213830
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR3	1.60e-05	3	81	2	9242641
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR3	1.60e-05	3	81	2	22948152
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR3 CELSR2	1.60e-05	3	81	2	11677057
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR3	1.60e-05	3	81	2	10788707
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR3	1.60e-05	3	81	2	25239916
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR3	1.60e-05	3	81	2	7621815
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR3	1.60e-05	3	81	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR3	1.60e-05	3	81	2	11159936
Pubmed	Significance of integrin αvβ5 and erbB3 in enhanced cell migration and liver metastasis of colon carcinomas stimulated by hepatocyte-derived heregulin.	ERBB3 ITGB5	1.60e-05	3	81	2	20626753
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR3	1.60e-05	3	81	2	10473538
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR3	1.60e-05	3	81	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR3	1.60e-05	3	81	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR3	1.60e-05	3	81	2	7635066
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	NCOR2 ERBB3 CELSR2 PITRM1 FMC1 ACLY RNF213 OAS3 GCNT2 CPSF2 TRIP11 MIER1 ITGB5	2.94e-05	1451	81	13	30550785
Pubmed	Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.	RYR1 RYR3	3.20e-05	4	81	2	22100703
Pubmed	Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers.	NCOR2 RXRA	3.20e-05	4	81	2	18362166
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR3	3.20e-05	4	81	2	18206662
Pubmed	A transcriptional co-repressor that interacts with nuclear hormone receptors.	NCOR2 RXRA	3.20e-05	4	81	2	7566127
Pubmed	A selective peroxisome proliferator-activated receptor-gamma modulator, telmisartan, binds to the receptor in a different fashion from thiazolidinediones.	NCOR2 RXRA	3.20e-05	4	81	2	19147680
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR3	3.20e-05	4	81	2	23413940
Pubmed	The retinoid X receptor binding to the thyroid hormone receptor: relationship with cofactor binding and transcriptional activity.	NCOR2 RXRA	3.20e-05	4	81	2	19211732
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR3	3.20e-05	4	81	2	9384575
Pubmed	Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.	MAPT SOS1	3.20e-05	4	81	2	26077951
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR3 CELSR2	3.20e-05	4	81	2	37224017
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR3	3.20e-05	4	81	2	9607712
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR3 CELSR2	3.20e-05	4	81	2	11850187
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR3	3.20e-05	4	81	2	23482488
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CELSR3 PITRM1 SZT2 NBEAL2 CPSF2 ZC3H7B MIER1 HEPH	3.30e-05	529	81	8	14621295
Pubmed	HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin.	HMGB1 ITGB5	5.33e-05	5	81	2	20826760
Pubmed	Nedd4 family interacting protein 1 (Ndfip1) is required for ubiquitination and nuclear trafficking of BRCA1-associated ATM activator 1 (BRAT1) during the DNA damage response.	ITCH BRAT1	5.33e-05	5	81	2	25631046
Pubmed	Epigenetic regulation of MicroRNA-122 by peroxisome proliferator activated receptor-gamma and hepatitis b virus X protein in hepatocellular carcinoma cells.	NCOR2 RXRA	5.33e-05	5	81	2	23703729
Pubmed	Characterization of receptor interaction and transcriptional repression by the corepressor SMRT.	NCOR2 RXRA	5.33e-05	5	81	2	9415406
Pubmed	Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.	RYR1 RYR3	5.33e-05	5	81	2	23918386
Pubmed	Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs.	ACOT6 ACOT4	5.33e-05	5	81	2	16940157
Pubmed	Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA.	NCOR2 RXRA	5.33e-05	5	81	2	10082574
Pubmed	Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.	RYR1 RYR3	5.33e-05	5	81	2	19011160
Pubmed	Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans.	NCOR2 RXRA	5.33e-05	5	81	2	20364085
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	NCOR2 ITCH WIZ MAPT PEX6 RNF213 OAS3 ZNF362 UNC5D ARAP2 SOS1	5.50e-05	1116	81	11	31753913
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ITCH CELSR2 NBEAL2 NAV1 CTNND1 CYSRT1 MIER1 ARAP2	5.51e-05	569	81	8	30639242
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	NCOR2 USP42 MAPT ACLY MYO18A CPSF2 MIER1 UNC5D SOS1	7.99e-05	774	81	9	15302935
Pubmed	Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.	RYR1 RYR3	7.99e-05	6	81	2	19549818
Pubmed	Impaired peroxisome proliferator-activated receptor gamma function through mutation of a conserved salt bridge (R425C) in familial partial lipodystrophy.	NCOR2 RXRA	7.99e-05	6	81	2	17312272
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	RYR1 RYR3	7.99e-05	6	81	2	26025922
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR1 RYR3	7.99e-05	6	81	2	23463619
Pubmed	Neuregulin-induced association of Sos Ras exchange protein with HER2(erbB2)/HER3(erbB3) receptor complexes in Schwann cells through a specific Grb2-HER2(erbB2) interaction.	ERBB3 SOS1	7.99e-05	6	81	2	11173924
Pubmed	Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.	RYR1 RYR3	7.99e-05	6	81	2	10444070
Pubmed	FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.	RYR1 RYR3	7.99e-05	6	81	2	14592808
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR1 RYR3	7.99e-05	6	81	2	20519450
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR1 RYR3	7.99e-05	6	81	2	25966694
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	RYR1 RYR3	7.99e-05	6	81	2	19009018
Pubmed	Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland.	ERBB3 SOS1	7.99e-05	6	81	2	11278868
Pubmed	The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators.	NCOR2 RXRA	7.99e-05	6	81	2	9878542
Pubmed	PSF is a novel corepressor that mediates its effect through Sin3A and the DNA binding domain of nuclear hormone receptors.	NCOR2 RXRA	7.99e-05	6	81	2	11259580
Pubmed	A component of the 26S proteasome binds on orphan member of the nuclear hormone receptor superfamily.	TRIP11 RXRA	7.99e-05	6	81	2	8603043
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR1 RYR3	7.99e-05	6	81	2	16844763
Pubmed	Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways.	NCOR2 RXRA	7.99e-05	6	81	2	11929748
Pubmed	Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.	CELSR3 CELSR2	1.12e-04	7	81	2	17937400
Pubmed	Isotype-restricted corepressor recruitment: a constitutively closed helix 12 conformation in retinoic acid receptors beta and gamma interferes with corepressor recruitment and prevents transcriptional repression.	NCOR2 RXRA	1.12e-04	7	81	2	12665583
Pubmed	ITCH-dependent proteasomal degradation of c-FLIP induced by the anti-HER3 antibody 9F7-F11 promotes DR5/caspase 8-mediated apoptosis of tumor cells.	ERBB3 ITCH	1.12e-04	7	81	2	31443721
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR1 RYR3	1.12e-04	7	81	2	11860456
Pubmed	Nuclear receptor corepressor-dependent repression of peroxisome-proliferator-activated receptor delta-mediated transactivation.	NCOR2 RXRA	1.12e-04	7	81	2	11903058
Pubmed	Analysis of the factors involved in the retinoic acid-induced differentiation of a retinoid-hypersensitive embryonal carcinoma cell mutant.	COL4A2 RXRA	1.12e-04	7	81	2	8299717
Pubmed	Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.	RYR1 RYR3	1.12e-04	7	81	2	20962236
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	DIS3L2 SPATS2L ACLY OAS3 CTNND1 CPSF2 ZC3H7B	1.14e-04	469	81	7	37314180
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	SZT2 MYO18A RNF213 RYR1 DOP1A	1.29e-04	208	81	5	33230847
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR1 RYR3	1.49e-04	8	81	2	19033399
Pubmed	Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.	RYR1 RYR3	1.49e-04	8	81	2	21441923
Pubmed	The basic helix-loop-helix proteins differentiated embryo chondrocyte (DEC) 1 and DEC2 function as corepressors of retinoid X receptors.	NCOR2 RXRA	1.49e-04	8	81	2	19786558
Pubmed	ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.	RYR1 RYR3	1.49e-04	8	81	2	30563862
Pubmed	Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.	RYR1 RYR3	1.49e-04	8	81	2	11784029
Pubmed	Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes.	NCOR2 WIZ MIER1	1.61e-04	45	81	3	21258344
Pubmed	A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response.	NCOR2 SPATS2L CTNND1 AHNAK2	1.71e-04	118	81	4	30979931
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	VPS13D SPATS2L WIZ PITRM1 ACADSB MARCHF2 NAV1 PEX6 RNF213 HMGB1 TRIP11 AHNAK2	1.74e-04	1496	81	12	32877691
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	VPS13D ITCH MAPT NAV1 CTNND1 TRIP11 ARAP2 DOP1A AHNAK2	1.78e-04	861	81	9	36931259
Pubmed	Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.	CELSR3 CELSR2	1.91e-04	9	81	2	9693030
Cytoband	14q24.3	CIPC ACOT6 ACOT4	6.12e-04	93	81	3	14q24.3
Cytoband	11q13.3	IGHMBP2 ANO1	6.94e-04	22	81	2	11q13.3
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR3 CELSR2	2.24e-05	3	50	2	913
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR3	2.24e-05	3	50	2	287
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR3 CELSR2	2.24e-05	3	50	2	1189
GeneFamily	Acyl-CoA thioesterases	ACOT6 ACOT4	3.33e-04	10	50	2	41
GeneFamily	PDZ domain containing	FRMPD4 MYO18A PREX2 AHNAK2	8.19e-04	152	50	4	1220
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R8 MAPT PREX2 RYR1	1.56e-03	181	50	4	694
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A2 FRMPD4 MAPT ANO1 ABLIM2 ITGB5	1.04e-06	185	80	6	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL4A2 FRMPD4 MAPT ANO1 ABLIM2 PREX2	1.11e-06	187	80	6	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	mild_COVID-19-cDC\|World / disease group, cell group and cell class (v2)	SPATS2L CD33 NAV1 GNA15 CTNND1 RYR1	1.50e-06	197	80	6	63e7b040c64f1e28b8db79980c7b580caa7d1b95
ToppCell	mild_COVID-19-cDC\|mild_COVID-19 / disease group, cell group and cell class (v2)	SPATS2L CD33 NAV1 GNA15 CTNND1 RYR1	1.50e-06	197	80	6	44ebd3f967779bb7753fc6dcd9fde6d682f9ccd6
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL4A2 FRMPD4 ANO1 PREX2 RYR1 NPNT	1.64e-06	200	80	6	2441a36d363b799a4692aa697f969cda056c2d60
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL4A2 FRMPD4 ANO1 PREX2 RYR1 NPNT	1.64e-06	200	80	6	c7bca638229bd4fd2414171e73fa949e36a10a92
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)-SCUBE3--L2-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	COL4A2 FRMPD4 ANO1 PREX2 RYR1 NPNT	1.64e-06	200	80	6	d841dbe2297c3bf62f49bae5921662cd6a47e5c2
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS14 CELSR3 CD33 CCDC78 GCNT2	7.57e-06	150	80	5	6e806a028c0519489151c181d9907e05289e27e0
ToppCell	droplet-Heart-nan-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS14 CELSR3 CD33 OAS3 LTB	9.74e-06	158	80	5	81a5a73090804d41429d297ba2462a842f39d380
ToppCell	droplet-Heart-nan-18m-Myeloid-cardiac_mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS14 CELSR3 CD33 OAS3 LTB	9.74e-06	158	80	5	9596b7b0f6f5157a43d67d2e67fb75a2624a6bb9
ToppCell	droplet-Heart-nan-18m-Myeloid-mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS14 CELSR3 CD33 OAS3 LTB	9.74e-06	158	80	5	7ebc8b778c97c0faa79e2d80c98b887fa635f901
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD33 AIPL1 NAV1 GNA15 AHNAK2	1.04e-05	160	80	5	5d22c86deead516444349d495998e04586be4396
ToppCell	PND07-Immune-Immune_Myeloid-Granulocytic-Mast\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD33 AIPL1 NAV1 GNA15 AHNAK2	1.04e-05	160	80	5	ca212634cf1875238071d1800ecdf34979a553fb
ToppCell	droplet-Heart-4Chambers-18m-Myeloid-cardiac_mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELL2 CD33 OAS3 LTB GCNT2	1.20e-05	165	80	5	a761e0a36d5da8fec916d684f81e60f5590fd9ee
ToppCell	droplet-Heart-4Chambers-18m-Myeloid-mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELL2 CD33 OAS3 LTB GCNT2	1.20e-05	165	80	5	680bdd150bc0a4e50244e57b1226a9b06a6bdbc9
ToppCell	droplet-Heart-4Chambers-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ELL2 CD33 OAS3 LTB GCNT2	1.20e-05	165	80	5	af423307af484661284793a08091777d998e6fba
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAPT TOGARAM2 ABLIM2 RYR3 NPNT	1.31e-05	168	80	5	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAPT TOGARAM2 ABLIM2 RYR3 NPNT	1.31e-05	168	80	5	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A2 GCNT2 CTNND1 ARAP2 NPNT	2.03e-05	184	80	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	COL4A2 NBEAL2 GCNT2 ARAP2 NPNT	2.03e-05	184	80	5	561592edc3083fad41b91811151b442207c65dd9
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A2 GCNT2 CTNND1 ARAP2 NPNT	2.03e-05	184	80	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 TOGARAM2 ANO1 ITGB5 PREX2	2.14e-05	186	80	5	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	COL4A2 NBEAL2 GCNT2 ARAP2 NPNT	2.20e-05	187	80	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 TOGARAM2 ANO1 UNC5D PREX2	2.25e-05	188	80	5	3139540a656c0436b2123ea50741ff8d00112165
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	COL4A2 FRMPD4 MAPT ABLIM2 PREX2	2.31e-05	189	80	5	d7ed96add29f219183c802895fbff519b627f635
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 ANO1 ITGB5 UNC5D PREX2	2.37e-05	190	80	5	2f54da2bee411f8868348a4c37034184b8f58a89
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	SPATS2L HMCN1 ACADSB PREX2 NPNT	2.37e-05	190	80	5	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPATS2L CD33 NAV1 GNA15 RYR1	2.43e-05	191	80	5	6cda82a994f4b205cf54590c979d7c9f3be2b4c8
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_6\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPATS2L CD33 NAV1 GNA15 RYR1	2.43e-05	191	80	5	4257f02856f3510981e9f84d465d91448d6126e2
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPATS2L CD33 NAV1 GNA15 RYR1	2.43e-05	191	80	5	2699e9bb872f2b561bb976dfdc2746e359bc9daf
ToppCell	PBMC-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPATS2L CD33 NAV1 GNA15 RYR1	2.43e-05	191	80	5	4b94c8b0183ae07d173646b7e7e1d9db04ec9637
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO1 GCNT2 UNC5D PREX2 NPNT	2.43e-05	191	80	5	fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCell	CD8+_Memory_T_cell-RSV-5\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	DOCK8-AS1 NAV1 GNA15 LTB RXRA	2.49e-05	192	80	5	6357af0fb60a13a0ac727bc922b7606ab520ef5c
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 ANO1 ITGB5 UNC5D PREX2	2.55e-05	193	80	5	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 ANO1 ITGB5 UNC5D PREX2	2.55e-05	193	80	5	3d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 ANO1 ITGB5 UNC5D PREX2	2.62e-05	194	80	5	52aebb0b563e2c2058e7f0554ae870e47692b163
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL4A2 ANO1 ITGB5 UNC5D PREX2	2.62e-05	194	80	5	bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 ERBB3 DNAH17 UNC5D NPNT	2.62e-05	194	80	5	8ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCell	normal_Lung-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	PLEKHG4B NAV1 GNA15 LTB PREX2	2.62e-05	194	80	5	d21461682fa755f588afe073abb6a777f339c4cc
ToppCell	(010)_cDC\|World / immune cells in Peripheral Blood (logTPM normalization)	SPATS2L CD33 NAV1 ITGB5 RYR1	2.68e-05	195	80	5	4aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPATS2L CD33 NAV1 GNA15 RYR1	2.75e-05	196	80	5	e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCell	Control-Myeloid-cDC\|Control / Disease group, lineage and cell class	SPATS2L CD33 NAV1 GNA15 RYR1	2.75e-05	196	80	5	85d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPATS2L CD33 NAV1 GNA15 RYR1	2.75e-05	196	80	5	553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPATS2L CD33 NAV1 GNA15 RYR1	2.75e-05	196	80	5	d376168e15ec1cf618723259966c76be3698b9b0
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPATS2L CD33 NAV1 GNA15 RYR1	2.75e-05	196	80	5	4a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCell	Healthy_donor-cDC\|Healthy_donor / disease group, cell group and cell class (v2)	SPATS2L CD33 NAV1 GNA15 RYR1	2.82e-05	197	80	5	b57a27e5b855bbdd1dfa352540599d260dc482aa
ToppCell	Healthy/Control-cDC\|World / Disease group and Cell class	SPATS2L CD33 NAV1 CTNND1 RYR1	2.82e-05	197	80	5	4497d4073f4d3e74de907325fba9eb4af5766bf4
ToppCell	Healthy_donor-cDC\|World / disease group, cell group and cell class (v2)	SPATS2L CD33 NAV1 CTNND1 RYR1	2.82e-05	197	80	5	a545fe3a80cd721bf01115bbb645753840ec9f40
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PLEKHG4B ERBB3 ACADSB GCNT2 NPNT	2.89e-05	198	80	5	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Mild-CD8+_T_activated\|Mild / Disease group and Cell class	SPATS2L RNF213 OAS3 ARAP2 DOP1A	2.89e-05	198	80	5	ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	SPATS2L HMGB1 TRIP11 AHNAK2 NPNT	2.96e-05	199	80	5	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL4A2 HMCN1 RNF213 CTNND1 PREX2	3.03e-05	200	80	5	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Control-Control-Myeloid-cDC\|Control / Disease, condition lineage and cell class	SPATS2L CD33 NAV1 GNA15 RYR1	3.03e-05	200	80	5	1375d199320feb85ba06e74b10df6521e790addf
ToppCell	control-cDC\|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SPATS2L CD33 NAV1 GNA15 RYR1	3.03e-05	200	80	5	4a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL4A2 RNF213 OAS3 CTNND1 PREX2	3.03e-05	200	80	5	3585484c7e24e941708bee471ca607d8ccee74e6
ToppCell	COVID-19-Heart-Fib_+_CM\|Heart / Disease (COVID-19 only), tissue and cell type	MAPT ACOT6 ABLIM2 RYR1	3.72e-05	104	80	4	0b60a56a46f1fe3f8224ec6399d009a34a117a21
ToppCell	COVID-19-Heart-Fib_+_CM\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAPT ACOT6 ABLIM2 RYR1	4.97e-05	112	80	4	d00ee6b19e41a35450681fe676885983536d6292
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Rrad\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RGS14 ALDH3B2 RYR1 NPNT	1.12e-04	138	80	4	b3a040c5d0e1cc94d9b19155bca8700edba2d243
ToppCell	droplet-Lung-nan-3m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 ITCH OAS3 RYR1	1.28e-04	143	80	4	4d11d53330a9197275a8851e1bbf55a113715a09
ToppCell	droplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 ITCH OAS3 RYR1	1.28e-04	143	80	4	8b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCell	MS-CD4-antiviral_CD4\|MS / Condition, Cell_class and T cell subcluster	SPATS2L RNF213 OAS3 LTB	1.62e-04	152	80	4	b1eba2d5a6da3eeb83d40a92976e3e8751ed18ee
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLEKHG4B SPATS2L NAV1 AHNAK2	1.71e-04	154	80	4	5967a0a33456d5930fc492a700ebb015ac050abb
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CELSR3 DNAH17 MYO18A	1.72e-04	60	80	3	28415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	CELSR3 DNAH17 MYO18A	1.72e-04	60	80	3	71eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCell	COVID-19-Heart-CM_5_(RYR2-)\|Heart / Disease (COVID-19 only), tissue and cell type	MAPT ITIH6 ABLIM2 RYR1	1.75e-04	155	80	4	d7e26696fd9c0a759524f331243db43059b33ed9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8-AS1 ABLIM2 RYR3 NPNT	1.75e-04	155	80	4	90e629681a72baacc7981b82883866a487638dbc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8-AS1 ABLIM2 RYR3 NPNT	1.75e-04	155	80	4	e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_11\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLEKHG4B SPATS2L NAV1 AHNAK2	1.75e-04	155	80	4	fab281db4c275d51240b122be78713c839ba5a95
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK8-AS1 ABLIM2 RYR3 NPNT	1.75e-04	155	80	4	5a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Agmat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RGS14 ALDH3B2 UNC5D NPNT	1.79e-04	156	80	4	09e0702400570089d9012dcf94dfb4827c97e49d
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RGS14 ALDH3B2 RYR1 NPNT	1.79e-04	156	80	4	2cd007b423c2395c5ce331902e7f27c805755eb3
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPATS2L NAV1 OAS3 CTNND1	1.84e-04	157	80	4	e9d0300361b06aec3c216f8af15f09e14b12a4da
ToppCell	droplet-Lung-LUNG-1m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD33 OAS3 LTB GCNT2	1.88e-04	158	80	4	30cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPATS2L NAV1 OAS3 CTNND1	1.88e-04	158	80	4	e9657d8960d499832f9f9b45b5a6f4388551b7e1
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD33 OAS3 LTB GCNT2	1.88e-04	158	80	4	47793463640f98ee5f680a1ee5786b453355fd57
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 ABLIM2 RYR3 NPNT	1.93e-04	159	80	4	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-cardiac_mast_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS14 CD33 OAS3 LTB	1.93e-04	159	80	4	766dfb9f9c0783e740a4fd395e99669310b33371
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 ABLIM2 RYR3 NPNT	1.93e-04	159	80	4	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 ABLIM2 RYR3 NPNT	1.93e-04	159	80	4	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VPS13D TOGARAM2 GNA15 BRAT1	1.97e-04	160	80	4	b2d8940ea8c068273b7da1589d3d6ae5110d8209
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VPS13D TOGARAM2 GNA15 BRAT1	1.97e-04	160	80	4	9caab1bb63c7e66c44783852ee75b16bb40fa594
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VPS13D TOGARAM2 GNA15 BRAT1	1.97e-04	160	80	4	229841be7b984a00a301cd5d88c11226a90d8a88
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VPS13D TOGARAM2 GNA15 BRAT1	1.97e-04	160	80	4	99c9ae2041445539fada842e1af01368669bfca0
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ACADSB CD33 PREX2 NPNT	2.02e-04	161	80	4	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RGS14 ALDH3B2 RYR1 NPNT	2.02e-04	161	80	4	e3327c296d48e821004e61a573abb75624a6f040
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	VPS13D MAPT MYO18A RYR1	2.02e-04	161	80	4	347edb0de10850b7d16c40945751033289289c9b
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PLEKHG4B GCNT2 ALDH3B2 NPNT	2.07e-04	162	80	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RGS14 DIS3L2 TOGARAM2 LTB	2.12e-04	163	80	4	9c91415a56b12b3b2d15d253bb59db8bedf49ea2
ToppCell	Ciliated_cells-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CCDC78 TOGARAM2 DLEC1 RYR3	2.17e-04	164	80	4	0e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC112 ERBB3 ANO1 ACOT6	2.27e-04	166	80	4	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC112 ERBB3 ANO1 ACOT6	2.27e-04	166	80	4	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TOGARAM2 RNF213 LTB ARAP2	2.27e-04	166	80	4	fb2cfbf1d0a0f1950dd24c08ba00ebd64b06ceb4
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC112 ERBB3 ANO1 ACOT6	2.32e-04	167	80	4	bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCell	facs-Skin-Anagen-24m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL2 TOGARAM2 ALDH3B2 CYSRT1	2.32e-04	167	80	4	02c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCell	facs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC112 ERBB3 ANO1 ACOT6	2.32e-04	167	80	4	9f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 ABLIM2 RYR3 NPNT	2.38e-04	168	80	4	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	metastatic_Lymph_Node-Myeloid_cells-CD141+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	PLEKHG4B LTB CYSRT1 PREX2	2.43e-04	169	80	4	a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	COL4A2 ABLIM2 UNC5D PREX2	2.54e-04	171	80	4	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Deuterosomal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DNAH17 CCDC78 TOGARAM2 DLEC1	2.60e-04	172	80	4	08ad76412c9cc3504141797b44b88478ced87476
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TOGARAM2 ABLIM2 RYR3 NPNT	2.60e-04	172	80	4	6c17a1e586a72d1bd80c20c06370429c61dc9f85
Drug	Fludrocortisone acetate [514-36-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	RGS14 ERBB3 VPS13D SZT2 DNAH17 ZC3H7B AHNAK2	6.61e-06	197	81	7	2328_UP
Drug	Isoxicam [34552-84-6]; Down 200; 12uM; HL60; HT_HG-U133A	SPATS2L WIZ SZT2 OAS3 ZC3H7B ITGB5 SOS1	6.83e-06	198	81	7	1862_DN
Drug	5'-adenylyl (beta,gamma-methylene)diphosphonate	RYR1 RYR3	1.25e-05	2	81	2	ctd:C005147
Drug	Clorgyline	CCDC112 ACADSB LTB TRIP11 PREX2 ARAP2	3.03e-05	168	81	6	ctd:D003010
Drug	2-hydroxycarbazole	RYR1 RYR3	3.74e-05	3	81	2	CID000093551
Drug	1,1'-diheptyl-4,4'-bipyridinium	RYR1 RYR3	3.74e-05	3	81	2	CID000080262
Drug	cis-diammineplatinum(II	RYR1 RYR3	3.74e-05	3	81	2	CID000159790
Drug	2-hydroxyheptanoic acid	RYR1 RYR3	3.74e-05	3	81	2	CID002750949
Drug	flubendiamide	RYR1 RYR3	3.74e-05	3	81	2	CID011193251
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR3	3.74e-05	3	81	2	CID005748312
Drug	8N3-cADPR	RYR1 RYR3	3.74e-05	3	81	2	CID000127713
Drug	aminodantrolene	RYR1 RYR3	3.74e-05	3	81	2	CID009570289
Drug	Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; PC3; HT_HG-U133A	RGS14 NCOR2 CELSR3 MAPT DNAH17 PREX2	6.57e-05	193	81	6	4067_DN
Drug	Amphotericin B [1397-89-3]; Down 200; 4.4uM; HL60; HT_HG-U133A	RGS14 VPS13D WIZ CELSR2 ACADSB ITGB5	7.16e-05	196	81	6	2441_DN
Drug	Methacholine chloride [62-51-1]; Down 200; 20.4uM; MCF7; HT_HG-U133A	VPS13D ITCH IGHMBP2 MARCHF2 CTNND1 SOS1	7.16e-05	196	81	6	6248_DN
Drug	Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A	VPS13D WIZ CELSR2 IGHMBP2 DNAH17 GNA15	7.36e-05	197	81	6	6801_UP
Drug	Kynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A	RGS14 NCOR2 SZT2 OAS3 GNA15 RYR1	7.36e-05	197	81	6	5276_UP
Drug	Succinylsulfathiazole [116-43-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A	VPS13D SZT2 DNAH17 OAS3 GCNT2 RXRA	7.36e-05	197	81	6	2821_UP
Drug	Dinoprost trometamol [38362-01-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	VPS13D WIZ IGHMBP2 OAS3 PREX2 AHNAK2	7.36e-05	197	81	6	3308_DN
Drug	A-30	RYR1 RYR3	7.47e-05	4	81	2	CID003028528
Drug	PCB74	RYR1 RYR3	7.47e-05	4	81	2	CID000036218
Drug	148504-47-6	RYR1 RYR3	7.47e-05	4	81	2	CID006444275
Drug	Bastadin 10	RYR1 RYR3	7.47e-05	4	81	2	CID009589366
Drug	SC 38249	RYR1 RYR3	7.47e-05	4	81	2	CID000134834
Drug	AC1L1U7A	RYR1 RYR3	7.47e-05	4	81	2	CID000035682
Drug	(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; PC3; HT_HG-U133A	RGS14 WIZ MAPT TRIP11 ITGB5 PREX2	7.57e-05	198	81	6	6657_DN
Drug	Piretanide [55837-27-9]; Down 200; 11uM; HL60; HT_HG-U133A	CELSR3 CELSR2 IGHMBP2 MARCHF2 OAS3 CTNND1	7.57e-05	198	81	6	6144_DN
Drug	Pirlindole mesylate [60762-57-4]; Up 200; 12.4uM; HL60; HT_HG-U133A	COL4A2 RGS14 WIZ CELSR3 OAS3 ZC3H7B	7.57e-05	198	81	6	3140_UP
Drug	Carbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; MCF7; HT_HG-U133A	NCOR2 WIZ CELSR3 GNA15 ZC3H7B AHNAK2	7.78e-05	199	81	6	3353_UP
Drug	sulindac sulfone; Up 200; 50uM; MCF7; HG-U133A	PPP1R8 VPS13D WIZ MAPT IGHMBP2 DNAH17	7.78e-05	199	81	6	309_UP
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	RGS14 MAPT IGHMBP2 DNAH17 GNA15 ZNF362	8.00e-05	200	81	6	4740_UP
Drug	Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A	COL4A2 WIZ ZNF362 ITGB5 RYR1 DOP1A	8.00e-05	200	81	6	6128_UP
Drug	Methylhydantoin-5-(L) [40856-73-3]; Down 200; 35uM; PC3; HT_HG-U133A	RGS14 VPS13D ITCH CELSR3 ZC3H7B TRIP11	8.00e-05	200	81	6	4618_DN
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR3	2.17e-05	3	80	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR3	2.17e-05	3	80	2	DOID:8545 (implicated_via_orthology)
Disease	cardiovascular event measurement, response to placebo	ACOT6 ACOT4	2.17e-05	3	80	2	EFO_0006919, EFO_0008344
Disease	aortic stenosis	CELSR2 NAV1 HMGB1	8.17e-05	31	80	3	EFO_0000266
Disease	chronic obstructive pulmonary disease	COL4A2 ERBB3 SPATS2L HMCN1 NAV1 DLEC1 ZNF362 ARAP2 NPNT	1.03e-04	688	80	9	EFO_0000341
Disease	X-16935 measurement	ACOT6 ACOT4	1.51e-04	7	80	2	EFO_0800763
Disease	hypertension	NCOR2 SZT2 RNF213 OAS3 LTB NPNT	1.90e-04	307	80	6	EFO_0000537
Disease	X-24747 measurement	ACOT6 ACOT4	2.01e-04	8	80	2	EFO_0022135
Disease	response to darapladib, cardiovascular event measurement	ACOT6 ACOT4	2.01e-04	8	80	2	EFO_0006919, EFO_0008395
Disease	X-17653 measurement	ACOT6 ACOT4	2.58e-04	9	80	2	EFO_0800783
Disease	FEV/FEC ratio	COL4A2 ERBB3 ITCH SPATS2L HMCN1 ANO1 NAV1 DLEC1 HMGB1P1 ARAP2 NPNT	4.67e-04	1228	80	11	EFO_0004713
Disease	Autosomal Dominant Myotubular Myopathy	CCDC78 RYR1	5.55e-04	13	80	2	C3661489
Disease	Centronuclear myopathy	CCDC78 RYR1	5.55e-04	13	80	2	C0175709
Disease	X-linked centronuclear myopathy	CCDC78 RYR1	5.55e-04	13	80	2	C0410203
Disease	undecenoylcarnitine (C11:1) measurement	ACOT6 ACOT4	5.55e-04	13	80	2	EFO_0800588
Disease	Congenital Structural Myopathy	CCDC78 RYR1	5.55e-04	13	80	2	C0752282
Disease	Myopathy, Centronuclear, 1	CCDC78 RYR1	5.55e-04	13	80	2	C4551952
Disease	Myopathy, Centronuclear, Autosomal Dominant	CCDC78 RYR1	6.47e-04	14	80	2	C1834558
Disease	Tubular Aggregate Myopathy	CCDC78 RYR1	6.47e-04	14	80	2	C0410207
Disease	glycerate measurement	HMCN1 RYR3	7.45e-04	15	80	2	EFO_0021029
Disease	Autosomal Recessive Centronuclear Myopathy	CCDC78 RYR1	7.45e-04	15	80	2	C3645536
Disease	migraine disorder, systolic blood pressure	RNF213 ITGB5	1.08e-03	18	80	2	EFO_0006335, MONDO_0005277
Disease	Congenital Fiber Type Disproportion	CCDC78 RYR1	1.08e-03	18	80	2	C0546264
Disease	cerebral infarction (is_marker_for)	HMGB1 SOS1	1.20e-03	19	80	2	DOID:3526 (is_marker_for)
Disease	hippocampal volume	HMGB1 ACOT6 ACOT4 RYR3 ARAP2	1.30e-03	297	80	5	EFO_0005035
Disease	pulmonary hypertension (biomarker_via_orthology)	CTNND1 RYR1 RYR3	1.36e-03	80	80	3	DOID:6432 (biomarker_via_orthology)
Disease	alcohol drinking	OAS3 HMGB1P1 ARAP2	1.41e-03	81	80	3	EFO_0004329
Disease	heart failure	SPATS2L CELSR2 MAPT GNA15	1.63e-03	185	80	4	EFO_0003144
Disease	migraine disorder, diastolic blood pressure	NCOR2 ITGB5	2.09e-03	25	80	2	EFO_0006336, MONDO_0005277

Protein segments in the cluster

Peptide	Gene	Start	Entry
IAPGPEPHGLTNKKL	ERBB3	986	P21860
GPTHMGPLALGILKL	BRAT1	291	Q6PJG6
QGLHGLVKIPKNDPL	ELL2	61	O00472
GVKKTILHGGTGELP	AIPL1	11	Q9NZN9
TKKIGPTGSGPLLHI	CCDC112	416	Q8NEF3
NLKGKGHGLSITPLP	CPSF2	136	Q9P2I0
HLLQPTEVPGPKGAK	CYSRT1	56	A8MQ03
QKENKGPGLTPTHLP	HTR3E	366	A5X5Y0
HIKGVKGDIGVPGIP	COL4A2	1031	P08572
LQHPKVKGPSIALLG	ACOT6	216	Q3I5F7
TPGLHIGKPENKLGL	ACADSB	241	P45954
LGKTLKPGLQGLLTG	DOP1A	136	Q5JWR5
KSDPLPGHGKNGLDQ	ABLIM2	511	Q6H8Q1
PEAPLGQPKGHKGLK	ARAP2	1641	Q8WZ64
LLGIGGHLSPQGKLT	CELSR2	116	Q9HCU4
PLPGSSAQPHKGILK	CELSR2	2826	Q9HCU4
KHLTPVTLELGGKNP	ALDH3B2	121	P48448
ILKRPGTQGHLGPEK	DIS3L2	856	Q8IYB7
ALGPLKLKPAHEGLV	NCOR2	1401	Q9Y618
KQPGPVKLGGEAAHL	NCOR2	2086	Q9Y618
LLKGVHGLVQGDEKP	ESPNL	606	Q6ZVH7
PKIKGEHPGLSIGDV	HMGB1	111	P09429
GPQHSPLAAGLLKKV	MARCHF2	226	Q9P0N8
PIHVPKGNGTILKGD	NPNT	266	Q6UXI9
KGKNITPGVLPPDHA	GCNT2	211	Q8N0V5
KQGHLPTILELGEGP	LRRC75A	291	Q8NAA5
KILIPGTLEPGHSKN	CD33	146	P20138
GPQEGDKKGQSPLLH	MYO18A	906	Q92614
LLHGPPGTGKTLLAK	PEX6	741	Q13608
GARSVKQDHPLPGKG	ANO1	91	Q5XXA6
GELKLLLLGPGESGK	GNA15	41	P30679
PHIALDGKLGGLVQP	ITGB5	281	P18084
GHPLLKKPGLSISEN	HMCN1	2141	Q96RW7
ILGEIKSHDLKPNGG	ITCH	711	Q96J02
GLVGLKLPHQPGGKG	FMC1	96	Q96HJ9
RLPGNVGKSGEPHKA	DOCK8-AS1	271	Q5T8R8
IKGKTLLPIPEHLGS	DNAH17	156	Q9UFH2
TGPENKGKHNLLGPD	FRMPD4	536	Q14CM0
QHGGPGALLSSPKKR	CCDC78	351	A2IDD5
KAGLHVSGKLLGAPP	ITIH6	1116	Q6UXX5
KVKQLHVGGLPPGSA	CELSR3	1891	Q9NYQ7
PKHGLLGPSEECQLK	DLEC1	1021	Q9Y238
LGLNGVLKVPAHPSG	RXRA	111	P19793
KQELEAKGGGTHPLL	RYR1	2891	P21817
KLKGIPVLVGLLDHP	CTNND1	406	O60716
INGPTGGNKKPLHAD	MIER1	426	Q8N108
KGRGSLPPQHGLELL	OAS3	961	Q9Y6K5
ISLGHPGSLKKGKTP	NAV1	521	Q8NEY1
LIKGINAGQLPAPKH	RTL1	191	A6NKG5
PLLGVHGIPKEQAVG	SZT2	1076	Q5T011
GKPPPGLHLDVVKGD	PPP1R8	21	Q12972
HPERPLLKKQLEGGL	SPATA31C2	396	B4DYI2
QKLSLDGNPKPIHGT	SPATS2L	156	Q9NUQ6
NLTPKGKQAPGGHEL	NARS1	186	O43776
KEKGLDLPGSIPGPH	TOGARAM2	191	Q6ZUX3
LLHQGGLSVGLAPKP	NBEAL2	2531	Q6ZNJ1
TGPEEHLGILGPLIK	HEPH	801	Q9BQS7
HLGILGPLIKGEVGD	HEPH	806	Q9BQS7
PKIKGEHPGLSIGDV	HMGB1P1	111	B2RPK0
HGLAILGPENPKIAK	PITRM1	1016	Q5JRX3
GPLPEKIELLAHKGL	SIAE	406	Q9HAT2
KQKGLPDAHLGLPPG	WIZ	916	O95785
LHLQPPPLGKKSDHG	SOS1	1231	Q07889
KHPDGKILIIGGSIA	ACLY	331	P53396
LQHPQVKGPGIGLLG	ACOT4	216	Q8N9L9
LPEGAGLKGHLPKVE	AHNAK2	1071	Q8IVF2
VPEGAGLKGHLPKLQ	AHNAK2	1401	Q8IVF2
VPEGAGLKGHLPKVD	AHNAK2	1896	Q8IVF2
VPEGAGLKGHLPKVE	AHNAK2	2061	Q8IVF2
VPEGAGLKGHLPKLQ	AHNAK2	2391	Q8IVF2
VPEGAGLKGHLPKVQ	AHNAK2	2556	Q8IVF2
VPEGAGLKGHLPKLQ	AHNAK2	2721	Q8IVF2
VPEGAGLKGHLPKVQ	AHNAK2	2886	Q8IVF2
VPEGAGLKGHLPKLQ	AHNAK2	3051	Q8IVF2
VLEGAGLKGHLPKLQ	AHNAK2	3216	Q8IVF2
VPEGAGLKGHLPKVE	AHNAK2	3381	Q8IVF2
VPEGAGLKGHLPKVE	AHNAK2	3546	Q8IVF2
LPKGAGLKGHLPKVQ	AHNAK2	4206	Q8IVF2
TKIAPHPGKRGLSLG	CIPC	161	Q9C0C6
HPGKRGLSLGPEEKG	CIPC	166	Q9C0C6
PKGGQKISPDTVLHL	RNF213	1551	Q63HN8
IKNPPHLNGTGPLKD	USP42	461	Q9H9J4
SLIAGHTGPVPKKPQ	UBN2	831	Q6ZU65
PKKEGSLKHGPEVGL	RYR3	4286	Q15413
QKELAIIHGPPGTGK	IGHMBP2	206	P38935
GAGVAVLKPHALGKP	PLEKHG4B	566	Q96PX9
PELKKLLHGLGLQDP	WDR97	1306	A6NE52
LEKLGLEIPPKLAGH	PISD	91	Q9UG56
QLLGDLHQEGPPLKG	MAPT	191	P10636
LPQRLKNGGGFKIHP	PREX2	1391	Q70Z35
LHRPGEKQPLDLGKL	RGS14	416	O43566
GGQLLEEPKLLHFKG	UNC5D	731	Q6UXZ4
GGPGHLLLKPISDVL	TRIP11	1941	Q15643
IKTIQGHGLLGPPKS	ZNF362	176	Q5T0B9
LKKHNPGKPGEGTPI	ZC3H7B	806	Q9UGR2
GLPAAHLIGAPLKGQ	LTB	86	Q06643
KPGSPELLVGHLGQI	VPS13D	1391	Q5THJ4