Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

FN1 ADAM9 ITGA10 ADAM11 ZYX

1.50e-05124525GO:0007229
DomainF-box

FBXO38 FBXO25 BTRC

8.60e-0467523PF00646
DomainDisintegrin_CS

ADAM9 ADAM11

8.90e-0416522IPR018358
DomainFBOX

FBXO38 FBXO25 BTRC

1.06e-0372523PS50181
DomainADAM_CR

ADAM9 ADAM11

1.13e-0318522PF08516
DomainF-box_dom

FBXO38 FBXO25 BTRC

1.19e-0375523IPR001810
DomainPDEase

PDE9A PDE1B

1.26e-0319522IPR023088
Domain-

ADAM9 ADAM11

1.40e-03205224.10.70.10
DomainPDEase_I

PDE9A PDE1B

1.54e-0321522PF00233
DomainDisintegrin

ADAM9 ADAM11

1.54e-0321522PF00200
DomainPDEASE_I

PDE9A PDE1B

1.54e-0321522PS00126
DomainPDEase_CS

PDE9A PDE1B

1.54e-0321522IPR023174
DomainDISIN

ADAM9 ADAM11

1.54e-0321522SM00050
Domain-

PDE9A PDE1B

1.69e-03225221.10.1300.10
DomainPDEase_catalytic_dom

PDE9A PDE1B

1.85e-0323522IPR002073
DomainHDc

PDE9A PDE1B

2.02e-0324522SM00471
DomainHD/PDEase_dom

PDE9A PDE1B

2.02e-0324522IPR003607
DomainACR

ADAM9 ADAM11

2.55e-0327522SM00608
DomainADAM_Cys-rich

ADAM9 ADAM11

2.55e-0327522IPR006586
DomainPeptidase_M12B_N

ADAM9 ADAM11

5.27e-0339522IPR002870
DomainPep_M12B_propep

ADAM9 ADAM11

5.27e-0339522PF01562
DomainDISINTEGRIN_1

ADAM9 ADAM11

5.54e-0340522PS00427
DomainReprolysin

ADAM9 ADAM11

5.54e-0340522PF01421
DomainADAM_MEPRO

ADAM9 ADAM11

5.54e-0340522PS50215
DomainDISINTEGRIN_2

ADAM9 ADAM11

5.54e-0340522PS50214
DomainPeptidase_M12B

ADAM9 ADAM11

5.54e-0340522IPR001590
DomainDisintegrin_dom

ADAM9 ADAM11

5.82e-0341522IPR001762
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOG_RAC_SIGNALING_PATHWAY

FN1 ITGA10 ELMO1

7.65e-0528423M47655
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_FAK_RAC_SIGNALING_PATHWAY

FN1 ITGA10 ELMO1

9.44e-0530423M47718
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DHX36 DDX46 ZNF507 SETD7 DNA2 DOCK6 CNOT1 LRRC47

1.32e-0652953814621295
Pubmed

Interactive structural analysis of βTrCP1 and PER2 phosphoswitch binding through dynamics simulation assay.

PER2 BTRC

2.28e-06253229856966
Pubmed

Constitutive and UV-induced fibronectin degradation is a ubiquitination-dependent process controlled by beta-TrCP.

FN1 BTRC

2.28e-06253216757476
Pubmed

The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2.

PER2 BTRC

6.83e-06353218782782
Pubmed

Differential effects of SUMO1 and SUMO2 on circadian protein PER2 stability and function.

PER2 BTRC

1.36e-05453234257372
Pubmed

Distinct control of PERIOD2 degradation and circadian rhythms by the oncoprotein and ubiquitin ligase MDM2.

PER2 BTRC

1.36e-05453230425162
Pubmed

Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.

NPTN MYO15A

1.36e-05453235100259
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ABHD14A OGT FN1 PDE9A ADAM9 DAAM2 ANKRD24 SNRNP70 SKIL BTRC

2.10e-051285531035914814
Pubmed

Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U.

SNRNP70 BTRC

2.27e-05553211850407
Pubmed

O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1.

OGT BTRC

2.27e-05553229941490
Pubmed

Early doors (Edo) mutant mouse reveals the importance of period 2 (PER2) PAS domain structure for circadian pacemaking.

PER2 BTRC

2.27e-05553226903623
Pubmed

Beta-catenin induces beta-TrCP-mediated PER2 degradation altering circadian clock gene expression in intestinal mucosa of ApcMin/+ mice.

PER2 BTRC

2.27e-05553219106159
Pubmed

Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation.

PER2 BTRC

2.27e-05553215767683
Pubmed

Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.

PER2 BTRC

3.40e-05653217462724
Pubmed

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.

NEDD4L SKIL

8.15e-05953215496141
Pubmed

Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.

FBXO38 FBXO25 BTRC

8.29e-055553337028429
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRERF1 NPTN OGT NEDD4L PDE1B ADAM9 DLGAP4 CNOT1

9.86e-0596353828671696
Pubmed

Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method.

NPTN FN1

1.24e-04115328938438
Pubmed

p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks.

PER2 NTRK3

1.24e-041153223785138
Pubmed

Evaluation of candidate markers for the peritubular myoid cell lineage in the developing mouse testis.

FN1 NTRK3

1.24e-041153216183868
Pubmed

O-GlcNAcylated LARP1 positively regulated by circCLNS1A facilitates hepatoblastoma progression through DKK4/β-catenin signalling.

OGT CNOT1

1.76e-041353237070251
Pubmed

Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases.

PDE9A PDE1B

1.76e-04135328557689
Pubmed

SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins.

PER2 BTRC

2.05e-041453217463251
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TRERF1 LIMD2 OGT ZNF507 SNRNP70 CNOT1 ZYX ELMO1

2.49e-04110353834189442
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

FBXO38 FBXO25 CDK15 NTRK3 BTRC

2.57e-0437253522939624
Pubmed

Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.

DHX36 NPTN GPAT3 EMC2 CNOT1

2.66e-0437553532788342
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SYNRG NEDD4L DLGAP4 EMC2 NFS1 SNRNP70 CNOT1 BTRC

3.09e-04113953836417873
Pubmed

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

NEDD4L BTRC

3.83e-041953221572392
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

NEDD4L PER2 ADAM9 DLGAP4 DAAM2

3.87e-0440753512693553
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

OGT CNOT1 BTRC LRRC47

3.96e-0422653425900982
Pubmed

¹H NMR metabolic profiling of plasma reveals additional phenotypes in knockout mouse models.

NPTN BTRC

4.25e-042053225849460
Pubmed

Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system.

ADAM9 ADAM11

4.25e-042053221068328
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX36 DDX46 FN1 SNRNP70 CNOT1 LRRC47

4.65e-0465353622586326
Pubmed

Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3.

PDE9A PDE1B

4.70e-042153227740716
Pubmed

Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.

NEDD4L BTRC

4.70e-042153237005481
Pubmed

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.

OGT SETD7

4.70e-042153212670868
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

TRERF1 DHX36 DDX46 NFS1 SNRNP70 ZYX

4.72e-0465553635819319
Pubmed

The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.

FBXO38 DDX46 OGT FN1

5.37e-0424553419521500
Pubmed

Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis.

FN1 ADAM9

5.65e-042353230814516
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

LIMD2 FBXO25 DLGAP4 CNOT1 QSOX2

6.11e-0445053516751776
Pubmed

Regulation of mesenchymal-to-epithelial transition by PARAXIS during somitogenesis.

FN1 DAAM2

6.16e-042453224038871
Pubmed

Mapping the Genetic Landscape of Human Cells.

DDX46 EMC2 SNRNP70 DNA2 CNOT1

6.17e-0445153530033366
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

DHX36 NEDD4L SNRNP70 LRRC47

6.51e-0425853437794589
Pubmed

Overview of PDEs and their regulation.

PDE9A PDE1B

6.68e-042553217307970
Pubmed

Holoprosencephaly Overview

CNOT1 DISP1

6.68e-042553220301702
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

FBXO38 OGT NEDD4L USP43 CNOT1 BTRC LRRC47

7.97e-04100553719615732
Pubmed

Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.

DHX36 DDX46 DNA2 BTRC LRRC47

8.62e-0448653530940648
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

NPTN ADAM9 NTRK3 DLGAP4

8.95e-0428153428706196
Pubmed

Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.

OGT CNOT1 BTRC

9.97e-0412853325332235
Pubmed

FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability.

FBXO38 BTRC

1.10e-033253235813202
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TRERF1 FBXO38 SYNRG DDX46 ZNF507 ZYX

1.12e-0377453615302935
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

TRERF1 OGT FN1

1.16e-0313553331077711
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

DHX36 DDX46 OGT NEDD4L SNRNP70 DOCK6 CNOT1

1.22e-03108253738697112
Pubmed

DNA Damage Regulates Translation through β-TRCP Targeting of CReP.

PER2 BTRC

1.31e-033553226091241
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DHX36 NPTN OGT NEDD4L FN1 DLGAP4 CNOT1 LRRC47

1.37e-03143153837142655
Pubmed

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.

OGT PER2 IL18R1

1.46e-0314653329688375
Pubmed

Identification of a family of human F-box proteins.

FBXO25 BTRC

1.47e-033753210531035
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SYNRG DDX46 OGT CNOT1 ZYX

1.48e-0354953538280479
GeneFamilyPhosphodiesterases

PDE9A PDE1B

1.21e-0324392681
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM9 ADAM11

1.54e-032739247
GeneFamilyCyclins|F-boxes other

FBXO38 FBXO25

3.19e-0339392560
GeneFamilyLIM domain containing

LIMD2 ZYX

7.18e-03593921218
ToppCellCOVID-19-kidney-REN+Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

TRERF1 FN1 PDE1B NTRK3 DAAM2 IL18R1

7.17e-08179536342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCellNS-control-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIK3AP1 LIMD2 PDE1B IL18R1 ELMO1

1.55e-061655358b2d43d7c4ee07bd999bd51bc15117ce1fbb2d86
ToppCellcontrol-Myeloid-pDC|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

PIK3AP1 LIMD2 PDE1B IL18R1 ELMO1

1.55e-06165535243c74adf8d993ff92acbff2768bdc5a1693eca3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 FN1 CDK15 NTRK3 DAAM2

3.18e-061915357b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 FN1 CDK15 NTRK3 DAAM2

3.18e-06191535cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 CDK15 GPAT3 IL18R1 ELMO1

3.70e-06197535bed8a9b73af5caee51b1232b31c24a59353658df
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 CDK15 GPAT3 IL18R1 ELMO1

3.70e-06197535b7d5073d44aa1e2cb83ea8d8104c5ed662665755
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 CDK15 GPAT3 IL18R1 ELMO1

3.79e-06198535cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 CDK15 GPAT3 IL18R1 ELMO1

3.79e-06198535d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 CDK15 GPAT3 IL18R1 ELMO1

3.98e-062005359156f8fd61a833891d2f7b7fadd693b81b1e2d5a
ToppCellParenchymal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRERF1 CDK15 GPAT3 IL18R1 ELMO1

3.98e-06200535566fe2e78e6f35399ec6aad5964f6d4d8ade82c6
ToppCellSigmoid-Dendritic_cell-cDC2|Dendritic_cell / Region, Cell class and subclass

SYNRG GPAT3 ELMO1

2.11e-05455335488dced1d338166f3021509ebe8673e03995978
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 NTRK3 DAAM2 IL18R1

3.84e-051595345ca96db4281abb5f646150ccf36adc66ab201c78
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 NTRK3 DAAM2 IL18R1

4.03e-051615341b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 CDK15 IL18R1 ELMO1

4.34e-051645342c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

FN1 ADAM9 GPAT3 IL18R1

4.55e-0516653465dafed953b01a9830b54309af75c7a561e88336
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

CDK15 GPAT3 IL18R1 ELMO1

4.87e-05169534fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellCOVID-19-lung-MAST|lung / Disease (COVID-19 only), tissue and cell type

TRERF1 CDK15 GPAT3 IL18R1

4.99e-05170534e90f18e5462381b38e918442b38b1c8105291908
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

CDK15 GPAT3 IL18R1 ELMO1

4.99e-05170534c80f6d29096c372da95a8407f402349ff1bb7018
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 NTRK3 DAAM2 IL18R1

4.99e-05170534876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 NTRK3 DAAM2 IL18R1

4.99e-051705341f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 NTRK3 DAAM2 IL18R1

5.22e-0517253408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|metastatic_Lymph_Node / Location, Cell class and cell subclass

OGT PDE1B ADAM9 DISP1

5.22e-05172534f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 NTRK3 DAAM2 IL18R1

5.22e-05172534553701349444eb366df3c11f54bb093434f153c6
ToppCell(0)_Normal/No_Treatment-(4)_COL2.3+_osteoblasts|(0)_Normal/No_Treatment / Stress and Cell class

NPTN FN1 ITGA10 SKIL

5.34e-05173534c2a0f674681836b5a868c13f67caa7d555ef6519
ToppCellfacs-SCAT-Fat-24m-Lymphocytic-T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIMD2 PGPEP1L KCNC1 IL18R1

5.46e-051745346ca9433d398aa3b48ecdc522dd545119e7c77dd4
ToppCellCOVID-19-kidney-REN+Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 NTRK3 DAAM2 IL18R1

5.46e-051745348393f0b43c767839c1630bcb952d62b42efc788d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 FN1 DAAM2 IL18R1

5.58e-0517553412f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SYNRG GPAT3 NFS1 QSOX2

5.71e-051765343c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCellCOVID-19-lung-MAST|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRERF1 CDK15 GPAT3 IL18R1

5.71e-05176534473c45a381ca109207d66ed1635668b391ea0e1f
ToppCellLA-17._Lymphocyte|World / Chamber and Cluster_Paper

TRERF1 CDK15 IL18R1 ELMO1

5.96e-0517853434ec499d03cc198cfefa19a724d4c81974052f65
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

TRERF1 FN1 NTRK3 DAAM2

6.50e-051825342075efeae633550fb2eb026d0dfd741c8252482e
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

TRERF1 ITGA10 DOCK6 DISP1

6.50e-051825348b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellP03|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NPTN OGT FN1 ZYX

6.92e-05185534a07dbe1f76e40734a28826423a5cc64b8e56af5e
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

OTOGL MUC19 DAAM2 PIWIL3

7.07e-0518653423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

OTOGL NTRK3 DAAM2 DOCK6

7.22e-0518753486250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1B NTRK3 DAAM2 IL18R1

7.22e-0518753415d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE1B NTRK3 DAAM2 IL18R1

7.22e-05187534f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 NTRK3 DAAM2 IL18R1

7.37e-0518853432f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

FN1 ITGA10 DOCK6 ELMO1

7.52e-05189534c81787a8c662db5d7814c583dd64562857629e81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 FN1 NTRK3 DAAM2

7.68e-0519053470c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellT_cells-Effector_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GPAT3 SETD7 SKIL IL18R1

7.68e-051905341af91fe0ee2c924e12f4db93c793e7af475d8f80
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FN1 NTRK3 DAAM2 ELMO1

7.83e-05191534fa380a8752de158974b2ae5e741573439719cc0d
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FN1 DAAM2 ZYX ELMO1

8.15e-051935349f69edc97b868d23998abc98928a2e89a885ef8a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FN1 NTRK3 DAAM2 ELMO1

8.32e-0519453471d3c7448b1734de54187f902f65649f9283bd4c
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FN1 ADAM9 ZYX ELMO1

8.32e-05194534d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FN1 ADAM9 ZYX ELMO1

8.32e-05194534e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FN1 ADAM9 DAAM2 ELMO1

8.32e-05194534a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellSevere-CD8+_T_activated|Severe / Disease group and Cell class

PIK3AP1 LIMD2 OGT ZYX

8.83e-05197534bb1e3e1d841c2c7141eb1099e7755860b168b6fc
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ITGA10 DOCK6 IL18R1 DISP1

8.83e-05197534ca6bce1a92c6326f41a6300c31da02386bafa152
ToppCellSevere-CD8+_T_activated|World / Disease group and Cell class

PIK3AP1 LIMD2 OGT ZYX

9.00e-051985345ff98c9b6c8c6863767b76c7745f263568f86acc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 FN1 NTRK3 DAAM2

9.00e-0519853479576525a10ed3e3a9d1608077cd16ecda23376f
ToppCellTracheal-10x5prime-Stromal-Chondrocytic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FN1 OTOGL ITGA10 DAAM2

9.00e-05198534c72ef2ddcbb6dacbed4c6200d89e17d57314dcdc
ToppCellTracheal-10x5prime-Stromal-Chondrocytic-Chondrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FN1 OTOGL ITGA10 DAAM2

9.00e-0519853455f013e9e6587d9ece59751fa131b1d22d6cceea
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FN1 ITGA10 DAAM2 DISP1

9.18e-05199534fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_capillary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ITGA10 DOCK6 IL18R1 DISP1

9.36e-052005345ab588808c1fc384019413401ab4bf9bc06bf529
ToppCellLung_Parenchyma-Control-Myeloid-cDC-DCs|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LIMD2 GPAT3 TMIGD3 IL18R1

9.36e-052005340576e34dc9a6adae5782659511d641781c6a44ed
ToppCellLung_Parenchyma-Control-Myeloid-cDC-DCs-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LIMD2 GPAT3 TMIGD3 IL18R1

9.36e-05200534b074b30cd7bb893c24cd49af1b2126825c59eef7
ToppCellParenchyma_Control_(B.)-Immune-TX-DCs|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LIMD2 GPAT3 TMIGD3 IL18R1

9.36e-05200534cae0e62804e41828e9cf74b9e3452c43a12bc87d
ToppCellLung_Parenchyma-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LIMD2 GPAT3 TMIGD3 IL18R1

9.36e-05200534337daee31dd5a277b9ef1dbd7fd6660371636084
ToppCellBiopsy_Other_PF-Immune-cDCs|Biopsy_Other_PF / Sample group, Lineage and Cell type

LIMD2 GPAT3 IL18R1 ELMO1

9.36e-052005348e455f685f0a9c63e83d6d339d7767f0e9841c6e
DrugDibucaine [85-79-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A

ABHD14A FBXO38 OGT SKIL DOCK6 BTRC

5.37e-061995161469_DN
Diseasecopine-1 measurement

DLGAP4 NFS1

4.07e-0417522EFO_0008102
DiseaseNodular glomerulosclerosis

FN1 ELMO1

2.39e-0341522C0017667
DiseaseDiabetic Nephropathy

FN1 ELMO1

2.75e-0344522C0011881
Diseaseureteral obstruction (biomarker_via_orthology)

FN1 SKIL

2.87e-0345522DOID:5199 (biomarker_via_orthology)
DiseaseX-12063 measurement

NEDD4L OTOGL EMC2

4.34e-03186523EFO_0021283
DiseaseHypertensive disease

NPTN NEDD4L FN1

4.61e-03190523C0020538
Diseaseaspartate aminotransferase measurement

PIK3AP1 NPTN NEDD4L MUC19 MYO15A SKIL

4.99e-03904526EFO_0004736
Diseaseprotein-glutamine gamma-glutamyltransferase e measurement

NPTN NEDD4L

5.05e-0360522EFO_0020690
Diseasepancreatic ductal carcinoma (is_marker_for)

ADAM9 NTRK3

5.22e-0361522DOID:3587 (is_marker_for)
Diseaseserum gamma-glutamyl transferase measurement

PIK3AP1 NPTN NEDD4L CYP7A1 ZYX PIWIL3

5.26e-03914526EFO_0004532

Protein segments in the cluster

PeptideGeneStartEntry
PPLHYLDQHNQNCLY

AZI2

376

Q9H6S1
YCRLSPNHKVLHYGD

ELMO1

576

Q92556
YGANCYRKNPVHFQH

APLF

381

Q8IW19
CHYQHGHINSYLKPM

BTRC

161

Q9Y297
DHCYYQGKLRGNPHS

ADAM11

131

O75078
YNALHLAAKYGHPQC

ANKRD24

116

Q8TF21
ALQAYSVANKHGHYP

PIK3AP1

361

Q6ZUJ8
AYKHLNYGPHSCQQM

DISP1

1276

Q96F81
KSCHQGLAYHYLQVP

DLGAP4

321

Q9Y2H0
KNQAVCHDYDIHFYP

QSOX2

126

Q6ZRP7
NAGHACYLHKPQDFH

ABHD14A

246

Q9BUJ0
HHCLQMPYKRNGGYF

DAAM2

381

Q86T65
AYGGCLVHLYNSHAL

OR2G2

96

Q8NGZ5
GYYSCVHFLHHNGKL

IL18R1

181

Q13478
ALHGEFYCKPHFQQL

LIMD2

81

Q9BT23
PKHHYPGCINLSFAY

NFS1

346

Q9Y697
YFRQGHNCHKPDTYV

NTRK3

516

Q16288
LQKCHYHHGANPLYS

MYO15A

1676

Q9UKN7
HRYLHLLDGNENYPC

LRRC47

436

Q8N1G4
SHCHYYLQERSKGQP

PER2

756

O15055
KYNFPGNCHFLAVHN

MUC19

831

Q7Z5P9
YYLSLHHGKGCAALI

PGPEP1L

131

A6NFU8
GKYKNPYHNQIHAAD

PDE1B

216

Q01064
CHDLDHPGYNNTYQI

PDE9A

351

O76083
HYPAKEQYGDTLHFC

FBXO25

306

Q8TCJ0
CIKYLAIYNCPHLHN

FBXO38

401

Q6PIJ6
HILNYYRTGKLHCPA

KCNC1

66

P48547
RGHCPQLAAYVHYAF

DOCK6

826

Q96HP0
CDLLASYQKGHHPAQ

CDK15

416

Q96Q40
HYHNKQYRPQKGGIC

GPAT3

211

Q53EU6
NGALCHFPFLYNNHN

FN1

416

P02751
VQPGHCYHLYNGLRA

DHX36

606

Q9H2U1
DHPNIQNHCHYRGYV

ADAM9

106

Q13443
AHNAPCAKGHLGDYQ

ITGA10

81

O75578
NPLSYHKVLCHGKYF

CYP7A1

81

P22680
PHNHLYCQQYAEVKY

EMC2

186

Q15006
KHLILVVNYSCPNHY

DDX46

686

Q7L014
YLHNFQCKHGAIPVT

DNA2

496

P51530
APCHYAHKLAYLVGQ

PIWIL3

851

Q7Z3Z3
NALAHYAYLCGQHGV

OTOGL

716

Q3ZCN5
PNHAVVHGNLACVYY

OGT

256

O15294
EKHHNQPYCGIAPYI

SNRNP70

31

P08621
HCYLHVNQKYLGTPE

SKIL

326

P12757
KLAYGGHQYHASCAN

SYNRG

1281

Q9UMZ2
LGHKANHSFTPNCIY

SETD7

291

Q8WTS6
KDYPQYCQHLASISH

CNOT1

966

A5YKK6
LYDLYAVCNHHGNLQ

USP43

651

Q70EL4
YHCVYHFVSAPKANA

NPTN

216

Q9Y639
CHYTSGNKGYIKQHL

ZNF507

646

Q8TCN5
QANRPHCVPDYHKQY

ZYX

486

Q15942
AICNYNAHYKNHPKY

TMIGD3

91

P0DMS9
PVRLKCHPLANYHYA

TRERF1

871

Q96PN7
HSIYKNGYCPNHPVI

NEDD4L

866

Q96PU5