Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	supramolecular fiber	TPT1 KIF27 NEBL CENPE SYNE1 HSPH1 BAG3 DBI CMYA5 NEB REEP3 NRP1 HOOK3 GABARAPL1 GABARAPL3 ARHGAP18	1.83e-04	1179	102	16	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	TPT1 KIF27 NEBL CENPE SYNE1 HSPH1 BAG3 DBI CMYA5 NEB REEP3 NRP1 HOOK3 GABARAPL1 GABARAPL3 ARHGAP18	1.98e-04	1187	102	16	GO:0099081
GeneOntologyCellularComponent	alpha DNA polymerase:primase complex	POLA1 MCM3	2.34e-04	5	102	2	GO:0005658
GeneOntologyCellularComponent	tRNA methyltransferase complex	TRMT10C TRMT6	4.87e-04	7	102	2	GO:0043527
HumanPheno	Head tremor	CEP104 SPTLC1 VPS13A DNMT1 TMEM63A	4.51e-06	47	28	5	HP:0002346
Domain	DUF1220	NBPF11 NBPF1 NBPF15 NBPF9	7.76e-08	9	95	4	SM01148
Domain	NBPF_dom	NBPF11 NBPF1 NBPF15 NBPF9	2.02e-07	11	95	4	IPR010630
Domain	NBPF	NBPF11 NBPF1 NBPF15 NBPF9	2.02e-07	11	95	4	PS51316
Domain	DUF1220	NBPF11 NBPF1 NBPF15 NBPF9	2.02e-07	11	95	4	PF06758
Domain	NEBU	NEBL NEB	1.53e-04	4	95	2	SM00227
Domain	Nebulin	NEBL NEB	1.53e-04	4	95	2	PF00880
Domain	Nebulin	NEBL NEB	1.53e-04	4	95	2	IPR013998
Domain	NEBULIN	NEBL NEB	1.53e-04	4	95	2	PS51216
Domain	Nebulin_repeat	NEBL NEB	1.53e-04	4	95	2	IPR000900
Domain	CUT	SATB2 CUX2	5.29e-04	7	95	2	PS51042
Domain	CUT	SATB2 CUX2	5.29e-04	7	95	2	PF02376
Domain	CUT_dom	SATB2 CUX2	5.29e-04	7	95	2	IPR003350
Domain	CUT	SATB2 CUX2	5.29e-04	7	95	2	SM01109
Domain	SH3_9	ARHGAP42 NEBL ITSN1 NEB	6.72e-04	78	95	4	PF14604
Domain	Atg8	GABARAPL1 GABARAPL3	7.03e-04	8	95	2	PF02991
Domain	Atg8-like	GABARAPL1 GABARAPL3	7.03e-04	8	95	2	IPR004241
Domain	Rho_GTPase_activation_prot	DAB2IP ARHGAP42 ARHGAP5 ARHGAP18	1.06e-03	88	95	4	IPR008936
Domain	SH3_1	ARHGAP42 NEBL TRIO ITSN1 NEB	1.51e-03	164	95	5	PF00018
Domain	HMG_box	SP100 TOX4 TOX3	2.48e-03	53	95	3	PF00505
Domain	HMG_BOX_2	SP100 TOX4 TOX3	2.62e-03	54	95	3	PS50118
Domain	HMG	SP100 TOX4 TOX3	2.62e-03	54	95	3	SM00398
Domain	-	SP100 TOX4 TOX3	2.76e-03	55	95	3	1.10.30.10
Domain	RhoGAP	ARHGAP42 ARHGAP5 ARHGAP18	3.88e-03	62	95	3	SM00324
Domain	RhoGAP	ARHGAP42 ARHGAP5 ARHGAP18	4.06e-03	63	95	3	PF00620
Domain	RHOGAP	ARHGAP42 ARHGAP5 ARHGAP18	4.24e-03	64	95	3	PS50238
Domain	RhoGAP_dom	ARHGAP42 ARHGAP5 ARHGAP18	4.24e-03	64	95	3	IPR000198
Domain	-	ARHGAP42 ARHGAP5 ARHGAP18	4.24e-03	64	95	3	1.10.555.10
Domain	HMG_box_dom	SP100 TOX4 TOX3	4.43e-03	65	95	3	IPR009071
Domain	SH3	ARHGAP42 NEBL TRIO ITSN1 NEB	4.93e-03	216	95	5	SM00326
Domain	SH3	ARHGAP42 NEBL TRIO ITSN1 NEB	4.93e-03	216	95	5	PS50002
Domain	SH3_domain	ARHGAP42 NEBL TRIO ITSN1 NEB	5.32e-03	220	95	5	IPR001452
Domain	-	TRIO GDAP2	6.04e-03	23	95	2	3.40.525.10
Domain	Spectrin	TRIO SYNE1	6.04e-03	23	95	2	PF00435
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF12 NBPF11 NBPF1 NBPF19 NBPF15 NBPF9 NBPF10	1.82e-13	21	103	7	16079250
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CYLC1 CEP104 TPT1 SP100 CUX2 SYNE1 ITSN1 HSPH1 UTP14A RPS27A NEB DNAJC7 FER1L6 NCOR1 PDIA6 SBNO1 CEBPZ VPS13A SYCP1 PPP1R9B PCID2	1.28e-09	1442	103	21	35575683
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF12 NBPF1 NBPF15 NBPF9	1.50e-08	10	103	4	22973535
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TRIO CENPE KIZ ITSN1 HSPH1 MCM3 DBI DNAJC7 ARHGAP5 NCOR1 HOOK3 ALMS1 CEP41 MORC3 PCID2	3.40e-08	853	103	15	28718761
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KIF27 TRIO POLA1 SYNE1 HSPH1 OTUB1 UTP14A SPTLC1 MCM3 CMYA5 DNAJC7 PDIA6 TRMT10C TRMT6 PAXBP1 SBNO1 CEBPZ DNMT1	1.92e-07	1425	103	18	30948266
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SYNE1 ZC3H13 ITSN1 HSPH1 OTUB1 BAG3 UTP14A SPTLC1 EXT2 RPS27A DNAJC7 WDR19 PDIA6 TRMT10C PAXBP1 CEBPZ VPS13A DNMT1	3.57e-07	1487	103	18	33957083
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NBPF12 CENPE NBPF11 NBPF1 CD2 NBPF9 NBPF10	7.87e-07	170	103	7	23314748
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	DAB2IP ZC3H13 CYP19A1 HSPH1 BAG3 MCM3 NCOR1 PDIA6 HOOK3 EIF3J	2.60e-06	503	103	10	16964243
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	NBPF12 TRIO MCM3 RPS27A NBPF11 NEB NBPF1 NBPF15 NBPF9 NBPF10	3.09e-06	513	103	10	25798074
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	ARHGAP42 TRIO ITSN1 BAG3 SPTLC1 MCM3 RPS27A ARHGAP5 TRMT10C TOX4 PPP1R9B ARHGAP28 ARHGAP18	3.25e-06	916	103	13	32203420
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	HSPH1 OTUB1 BAG3 UTP14A MCM3 RPS27A DNAJC7 PIAS4 PDIA6 CD2 TRMT10C CEBPZ DNMT1	7.41e-06	989	103	13	36424410
Pubmed	Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions.	NEBL NEB	8.69e-06	2	103	2	19851499
Pubmed	Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.	NBPF11 NBPF1	8.69e-06	2	103	2	7700633
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BDP1 CENPE ITSN1 MCM3 DNAJC7 PIAS4 NCOR1 ALMS1 SECISBP2 MORC3	1.02e-05	588	103	10	38580884
Pubmed	Functional proteomics mapping of a human signaling pathway.	ITSN1 OTUB1 RPS27A DNAJC7 PIAS4 ARHGAP5 NCOR1 TOX4 SECISBP2 PPP1R9B	1.07e-05	591	103	10	15231748
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DAB2IP BDP1 SYNE1 NBPF1 CMIP	1.37e-05	102	103	5	11214970
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	DAB2IP TRIO BAG3 DNAJC7 ARHGAP5 NCOR1 PDIA6 TRMT10C TOX4 CEBPZ VPS13A PPP1R9B DNMT1	1.38e-05	1049	103	13	27880917
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	POLA1 HSPH1 BAG3 UTP14A MCM3 RPS27A DNAJC7 PDIA6 TRMT10C PAXBP1 MGST3 SBNO1 CEBPZ EIF3J DNMT1	1.82e-05	1415	103	15	28515276
Pubmed	Targeting the P2Y13 Receptor Suppresses IL-33 and HMGB1 Release and Ameliorates Experimental Asthma.	P2RY13 IL33	2.60e-05	3	103	2	34860143
Pubmed	Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.	EXT2 SULF2	2.60e-05	3	103	2	17116694
Pubmed	Tightening the retinal glia limitans attenuates neuroinflammation after optic nerve injury.	CASP4 MMP3	2.60e-05	3	103	2	32645232
Pubmed	The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution.	TRMT10C TRMT6	2.60e-05	3	103	2	29072297
Pubmed	Gene expression analysis of the embryonic subplate.	SATB2 CUX2 NEBL DBI NRP1 SULF2	2.69e-05	196	103	6	21862448
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	SYNE1 ZC3H13 HSPH1 BAG3 TOX4 PAXBP1	2.77e-05	197	103	6	20811636
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	TPT1 TRIO HSPH1 OTUB1 SPTLC1 EXT2 RPS27A DNAJC7 NCOR1 PDIA6 TRMT10C COA6 PCID2 DNMT1	2.92e-05	1297	103	14	33545068
Pubmed	SARS-CoV-2 NSP12 associates with TRiC and the P323L substitution acts as a host adaption.	HSPH1 SPTLC1 MCM3 RPS27A DNAJC7	3.01e-05	120	103	5	37929963
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	TRIO SYNE1 ITSN1 DNAJC7 ALMS1	3.01e-05	120	103	5	31413325
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	ZC3H13 HSPH1 UTP14A SPTLC1 MCM3 RPS27A NCOR1 TRMT10C TOX4 PAXBP1 CEBPZ MORC3 PCID2 DNMT1	3.48e-05	1318	103	14	30463901
Pubmed	Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein.	GABARAPL1 GABARAPL3	5.19e-05	4	103	2	11414770
Pubmed	Differential epigenetic regulation of TOX subfamily high mobility group box genes in lung and breast cancers.	TOX4 TOX3	5.19e-05	4	103	2	22496870
Pubmed	Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling.	NEBL NEB	5.19e-05	4	103	2	23985323
Pubmed	Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion.	SATB2 CUX2 NRP1	5.53e-05	25	103	3	39271675
Pubmed	Dynamic regulation of p53 subnuclear localization and senescence by MORC3.	SP100 MORC3	8.64e-05	5	103	2	17332504
Pubmed	Chibby interacts with NBPF1 and clusterin, two candidate tumor suppressors linked to neuroblastoma.	NBPF11 NBPF1	8.64e-05	5	103	2	20096688
Pubmed	The circadian factor Period 2 modulates p53 stability and transcriptional activity in unstressed cells.	TPT1 CRY1	8.64e-05	5	103	2	25103245
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TRIO SYNE1 ITSN1 HSPH1 RPS27A CMYA5 DNAJC7 WDR19 ARHGAP5 SBNO1 STAMBPL1 MORC3 DNMT1	1.10e-04	1285	103	13	35914814
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HSPH1 UTP14A TOX4 CMIP ALMS1 ARHGAP28 MORC3 TMEM63A	1.13e-04	493	103	8	15368895
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	HSPH1 BAG3 MCM3 RPS27A DNAJC7 PDIA6 TRMT10C EIF3J	1.16e-04	495	103	8	28581483
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	ZC3H13 UTP14A MCM3 PDIA6 EIF3J	1.29e-04	163	103	5	22113938
Pubmed	SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR.	PIAS4 NCOR1	1.29e-04	6	103	2	19955185
Pubmed	Negative regulation of CD8 expression via Cd8 enhancer-mediated recruitment of the zinc finger protein MAZR.	NCOR1 DNMT1	1.29e-04	6	103	2	16491076
Pubmed	Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models.	ALMS1 RPE65	1.29e-04	6	103	2	37252956
Pubmed	p300-mediated acetylation stabilizes the Th-inducing POK factor.	HSPH1 CEBPZ	1.29e-04	6	103	2	20810990
Pubmed	A DNM2 Centronuclear Myopathy Mutation Reveals a Link between Recycling Endosome Scission and Autophagy.	ITSN1 GABARAPL1	1.29e-04	6	103	2	32315611
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	CENPE SYNE1 NT5C3A MTG2 UTP14A SPTLC1 RPS27A DNAJC7 TRMT10C TRMT6 ALMS1 TOX3 VPS13A SECISBP2	1.34e-04	1496	103	14	32877691
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DAB2IP TRIO CENPE SYNE1 ITSN1 MCM3 RPS27A NCOR1 HOOK3 PPP1R9B DNMT1	1.36e-04	963	103	11	28671696
Pubmed	The DNA sequence and analysis of human chromosome 13.	RNASEH2B TPT1 ZC3H13 HSPH1 PCID2	1.56e-04	170	103	5	15057823
Pubmed	Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons.	SATB2 NRP1	1.81e-04	7	103	2	29779877
Pubmed	Arhgap28 is a RhoGAP that inactivates RhoA and downregulates stress fibers.	ARHGAP28 ARHGAP18	1.81e-04	7	103	2	25211221
Pubmed	POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.	KIF27 CENPE KIZ RPS27A CMYA5 ARHGAP18	1.81e-04	277	103	6	30745168
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	SYNE1 HSPH1 MCM3 RPS27A CMYA5 NEB DNAJC7 PDIA6 MGST3 SYCP1	2.08e-04	844	103	10	25963833
Pubmed	FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ.	TPT1 SP100 SATB2 PIAS4 NCOR1	2.20e-04	183	103	5	36129980
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	BAG3 MCM3 DNAJC7 NCOR1 TOX4 ALMS1 CEBPZ DNMT1	2.34e-04	549	103	8	38280479
Pubmed	Microtubule-associated protein 6 mediates neuronal connectivity through Semaphorin 3E-dependent signalling for axonal growth.	ITSN1 NRP1	2.40e-04	8	103	2	26037503
Pubmed	An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse.	WDR19 DNMT1	2.40e-04	8	103	2	15890782
Pubmed	Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies.	NEBL NEB	2.40e-04	8	103	2	11309420
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SYNE1 ZC3H13 RPS27A ALMS1 CEBPZ	2.43e-04	187	103	5	26460568
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	BDP1 NBPF12 SYNE1 SULF2	2.56e-04	103	103	4	10574462
Pubmed	Genome wide association study of age at menarche in the Japanese population.	ARHGAP42 CMIP	3.08e-04	9	103	2	23667675
Pubmed	Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly.	SATB2 CUX2	3.08e-04	9	103	2	22284184
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	NEBL HSPH1 BAG3 UTP14A MCM3 RPS27A DNAJC7 NCOR1 PAXBP1 CEBPZ EIF3J PCID2	3.25e-04	1247	103	12	27684187
Pubmed	AIMP2-DX2 provides therapeutic interface to control KRAS-driven tumorigenesis.	HSPH1 OTUB1 MCM3 DNAJC7 PDIA6	3.32e-04	200	103	5	35546148
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	NT5C3A HSPH1 OTUB1 SPTLC1 MCM3 RPS27A DNAJC7 PDIA6 TRMT10C HOOK3 CEBPZ DDX60L EIF3J	3.34e-04	1440	103	13	30833792
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NEBL TRIO CENPE ITSN1 REEP3 ALMS1 CEBPZ SECISBP2 DNMT1	3.37e-04	733	103	9	34672954
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CENPE POLA1 ZC3H13 ITSN1 HSPH1 ARHGAP5 TRMT6 VPS13A RPE65	3.47e-04	736	103	9	29676528
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RNASEH2B SP100 POLA1 HSPH1 BAG3 MCM3 RPS27A CMYA5 DNAJC7 PDIA6 TRMT6 SBNO1 EIF3J	3.69e-04	1455	103	13	22863883
Pubmed	Single-cell multiomics decodes regulatory programs for mouse secondary palate development.	SATB2 NRP1	3.85e-04	10	103	2	38280850
Pubmed	Diet-mediated constitutive induction of novel IL-4+ ILC2 cells maintains intestinal homeostasis in mice.	IL33 DNMT1	3.85e-04	10	103	2	37163450
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	HSPH1 OTUB1 NEB PDIA6 CMIP ARHGAP28	4.05e-04	322	103	6	26514267
Pubmed	A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation.	SATB2 CUX2 NRP1	4.47e-04	50	103	3	22365545
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	BDP1 ABCC4 TRIO INPP5A KIZ REEP3 NBPF1 NRP1 PIAS4 CMIP TOX3 PPP1R9B TMEM63A	4.59e-04	1489	103	13	28611215
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	NEBL HSPH1 BAG3 UTP14A RPS27A PDIA6 TOX4 ALMS1 PPP1R9B DNMT1	4.62e-04	934	103	10	33916271
Pubmed	Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.	HSPH1 BAG3	4.69e-04	11	103	2	24318877
Pubmed	The proto-oncoprotein FBI-1 interacts with MBD3 to recruit the Mi-2/NuRD-HDAC complex and BCoR and to silence p21WAF/CDKN1A by DNA methylation.	NCOR1 DNMT1	4.69e-04	11	103	2	23658227
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	POLA1 MCM3 PIAS4 NCOR1 MORC3 DNMT1	4.76e-04	332	103	6	32786267
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	SP100 SYNE1 UTP14A CEBPZ DDX60L PCID2	4.76e-04	332	103	6	25693804
Pubmed	Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.	SYNE1 MCM3 CMYA5	5.02e-04	52	103	3	26499835
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	TPT1 MTG2 ITSN1 OTUB1 UTP14A MCM3 EXT2 DBI FBXL5 CEBPZ DNMT1	5.07e-04	1124	103	11	21900206
Pubmed	Cellular redox sensor HSCARG negatively regulates the translesion synthesis pathway and exacerbates mammary tumorigenesis.	NT5C3A RPS27A DNAJC7 MGST3 PPP1R9B	5.23e-04	221	103	5	31796584
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SATB2 PIAS4 ZNF770 MORC3	5.34e-04	125	103	4	32891193
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	HSPH1 UTP14A MCM3 DNAJC7 NCOR1 PDIA6 PPP1R9B PCID2	5.48e-04	624	103	8	33729478
Pubmed	Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure.	SATB2 NRP1	5.62e-04	12	103	2	37610874
Pubmed	CXCR4 and CXCR7 have distinct functions in regulating interneuron migration.	SATB2 CUX2	5.62e-04	12	103	2	21220099
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	RNASEH2B TPT1 POLA1 INPP5A HSPH1 UTP14A SPTLC1 CCDC178 FBXL5 COA6 SBNO1 EIF3J	5.65e-04	1327	103	12	32694731
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DAB2IP CUX2 SYNE1 SULF2 ALMS1	5.67e-04	225	103	5	12168954
Pubmed	A human MAP kinase interactome.	SP100 SYNE1 ITSN1 BAG3 NEB DNAJC7 TOX4	6.23e-04	486	103	7	20936779
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	HSPH1 BAG3 MCM3 DNAJC7 PDIA6 TRMT10C COA6 TRMT6 CEBPZ DNMT1	6.23e-04	971	103	10	33306668
Pubmed	Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.	DAB2IP CCDC178 ALMS1	6.24e-04	56	103	3	23934736
Pubmed	The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.	TRIO TRMT10C HOOK3 GABARAPL1 CEP41	6.26e-04	230	103	5	35449600
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	CENPE KIZ SYNE1 CRY1 PDIA6 TOX4 PAXBP1 MGST3 SYCP1 MORC3 EIF3J	6.35e-04	1155	103	11	20360068
Pubmed	Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities.	SATB2 TOX3	6.63e-04	13	103	2	30705426
Pubmed	Fate-restricted neural progenitors in the mammalian cerebral cortex.	SATB2 CUX2	6.63e-04	13	103	2	22879516
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	CENPE SYNE1 NEB FER1L6 SYCP1	6.77e-04	234	103	5	36243803
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	TRIO SYNE1 CMYA5 NEB NCOR1 HOOK3 ALMS1	7.10e-04	497	103	7	23414517
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	ITSN1 RPS27A ALMS1	7.64e-04	60	103	3	34761192
Pubmed	COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression.	SATB2 CUX2	7.72e-04	14	103	2	21965613
Pubmed	DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex.	SATB2 MGST3	8.89e-04	15	103	2	25556833
Pubmed	Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice.	SATB2 NRP1	8.89e-04	15	103	2	19961580
Pubmed	CUL2LRR1 , TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle.	POLA1 MCM3	8.89e-04	15	103	2	33590678
Pubmed	Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex.	SATB2 CUX2	8.89e-04	15	103	2	18255031
Interaction	C6orf141 interactions	SATB2 RPS27A WDR19 NCOR1 ALMS1 MORC3	7.27e-06	92	102	6	int:C6orf141
Cytoband	10p12	NEBL NRP1	1.04e-04	7	103	2	10p12
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	NBPF12 NBPF11 NBPF19 NBPF15 NBPF9 NBPF10	3.12e-04	404	103	6	chr1q21
Cytoband	1q21.1	NBPF11 NBPF9 NBPF10	3.77e-04	62	103	3	1q21.1
Cytoband	9q22.2	SPTLC1 SECISBP2	6.63e-04	17	103	2	9q22.2
Cytoband	5q13	BDP1 BHMT2	1.12e-03	22	103	2	5q13
Cytoband	Ensembl 112 genes in cytogenetic band chr11q22	ARHGAP42 CASP4 MMP3	1.84e-03	107	103	3	chr11q22
Cytoband	15q21.1	CYP19A1 EIF3J	3.15e-03	37	103	2	15q21.1
GeneFamily	Neuroblastoma breakpoint family	NBPF12 NBPF11 NBPF1 NBPF19 NBPF15 NBPF9 NBPF10	2.24e-12	23	70	7	662
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	ARHGAP42 ARHGAP5 ARHGAP28 ARHGAP18	4.15e-05	50	70	4	721
GeneFamily	CUT class homeoboxes and pseudogenes	SATB2 CUX2	5.23e-04	9	70	2	527
Coexpression	GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_UP	BDP1 SP100 KIF27 KIZ SYNE1 CEBPZ SYCP1	2.09e-06	152	101	7	M2964
Coexpression	PIEPOLI_LGI1_TARGETS_DN	ITSN1 MMP3 IL33	3.63e-05	17	101	3	M2835
Coexpression	GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN	DAB2IP CEP104 RNASEH2B NRP1 ARHGAP18 ACOXL	4.70e-05	167	101	6	M6699
Coexpression	GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP	CASP4 ATP10D WDR19 PIAS4 PDIA6 P2RX5	6.49e-05	177	101	6	M5641
Coexpression	GOLDRATH_ANTIGEN_RESPONSE	RNASEH2B SP100 POLA1 ITSN1 BAG3 MCM3 DBI NRP1	8.75e-05	366	101	8	M11884
Coexpression	GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP	INPP5A KIZ BAG3 FBXL5 WDR19 GABARAPL1	1.11e-04	195	101	6	M4195
Coexpression	GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP	NEB ATP10D NCOR1 CD2 NBPF10 PCID2	1.11e-04	195	101	6	M3184
Coexpression	GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN	INPP5A RPS27A ALMS1 SCML1 SECISBP2 CCDC180	1.17e-04	197	101	6	M8611
Coexpression	GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP	DAB2IP TRIO FBXL5 SCML1 DDX60L STAMBPL1	1.20e-04	198	101	6	M6166
Coexpression	HALLMARK_MITOTIC_SPINDLE	TRIO CENPE ITSN1 ARHGAP5 HOOK3 ALMS1	1.24e-04	199	101	6	M5893
Coexpression	GSE30153_LUPUS_VS_HEALTHY_DONOR_BCELL_UP	SATB2 CRY1 PIAS4 TOX3 VPS13A RPE65	1.24e-04	199	101	6	M8425
Coexpression	GSE10325_CD4_TCELL_VS_MYELOID_UP	SYNE1 BAG3 CD2 PCID2 DNMT1 TMEM63A	1.24e-04	199	101	6	M3078
Coexpression	GSE3039_NKT_CELL_VS_B1_BCELL_DN	RNASEH2B POLA1 NRP1 SULF2 CEP41 ARHGAP18	1.27e-04	200	101	6	M6433
Coexpression	GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_DN	BDP1 TRIO GABARAPL1 PKD2L2 TOX3 MMP3	1.27e-04	200	101	6	M8225
Coexpression	GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN	INPP5A NT5C3A ITSN1 CASP4 NRP1 ARHGAP18	1.27e-04	200	101	6	M7347
Coexpression	KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP	RNASEH2B GDAP2 DBI CRY1 COA6 GABARAPL1	1.27e-04	200	101	6	M3027
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	BDP1 SP100 CUX2 CENPE POLA1 KIZ HSPH1 UTP14A WDR19 NCOR1 TRMT6 ALMS1 CEBPZ TOX3 VPS13A EIF3J	1.68e-05	989	101	16	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K1	RNASEH2B ABCC4 NEBL CENPE ZC3H13 HSPH1 UTP14A MCM3 RPS27A CRY1 TRMT10C TRMT6 ALMS1 CEBPZ TOX3 ZNF770 EIF3J	3.29e-05	1164	101	17	facebase_RNAseq_e8.5_NeuroEpith_hindBrain_2500_K1
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ARHGAP42 ABCC4 SATB2 NEBL NRP1 VPS13A BHMT2	2.43e-07	184	103	7	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)\|10x_3'_v3 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TPT1 HSPH1 DBI NRP1 GABARAPL1 MGST3 ARHGAP18	3.99e-07	198	103	7	ff9c97c6f579a4e79859d420f224556fadc1f6ab
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	SP100 KIZ ZC3H13 HSPH1 RPS27A ANKRD18B SBNO1	4.12e-07	199	103	7	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Sigmoid-T_cell-Th1\|T_cell / Region, Cell class and subclass	TPT1 INPP5A HSPH1 BAG3 NBPF19 CD2 P2RX5	4.26e-07	200	103	7	bc9433a8ec3a6f10816730a32b821c63d78e6e87
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated\|COVID-19_Mild / Disease, condition lineage and cell class	SP100 HSPH1 ANKRD18B NBPF1 CD2 STAMBPL1 TMEM63A	4.26e-07	200	103	7	d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP4 ARHGAP5 NCOR1 CMIP SBNO1 CEBPZ	5.02e-06	188	103	6	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	SP100 KIZ NT5C3A ZC3H13 RPS27A GABARAPL1	6.95e-06	199	103	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	CEP104 ZC3H13 ITSN1 HSPH1 SBNO1 ZNF770	6.95e-06	199	103	6	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NEBL SYNE1 ITSN1 NRP1 NBPF19 NBPF10	7.15e-06	200	103	6	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NEBL SYNE1 ITSN1 NRP1 NBPF19 NBPF10	7.15e-06	200	103	6	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NEBL SYNE1 ITSN1 NRP1 NBPF19 NBPF10	7.15e-06	200	103	6	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NEBL SYNE1 ITSN1 NRP1 NBPF19 NBPF10	7.15e-06	200	103	6	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	NEBL SYNE1 ITSN1 NRP1 NBPF19 NBPF10	7.15e-06	200	103	6	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	Control-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NBPF12 NBPF11 NBPF1 NBPF15 NBPF10	2.13e-05	144	103	5	984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MTG2 ZKSCAN7 CD2 CEBPZ PPP1R9B	2.76e-05	152	103	5	5adcdf93fd3ca066402aaaf308c363e4648f871d
ToppCell	PND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SP100 MCM3 CD2 CCDC180 DNMT1	4.09e-05	165	103	5	66f0364098d82629aa2ec1dfe0c5ad23de7c2c12
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NBPF12 NBPF11 NBPF1 NBPF15 NBPF10	4.33e-05	167	103	5	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC4 FER1L6 TOX3 ARHGAP28 ARHGAP18	4.58e-05	169	103	5	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	droplet-Fat-Scat-21m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB2IP SATB2 NEBL NEB ZNF770	5.12e-05	173	103	5	f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC4 FER1L6 TOX3 ARHGAP28 ARHGAP18	5.12e-05	173	103	5	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	Severe-CD4+_T_activated\|Severe / Disease group and Cell class	TPT1 NT5C3A HSPH1 BAG3 DDX60L	5.71e-05	177	103	5	a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCell	Severe-CD4+_T_activated\|World / Disease group and Cell class	TPT1 NT5C3A HSPH1 BAG3 DDX60L	5.86e-05	178	103	5	ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SATB2 SYNE1 NT5C3A ITSN1 VPS13A	6.18e-05	180	103	5	ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SATB2 SYNE1 NT5C3A ITSN1 VPS13A	6.18e-05	180	103	5	4e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCell	E18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SATB2 SYNE1 NT5C3A ITSN1 VPS13A	6.18e-05	180	103	5	466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CEP104 CRY1 NBPF9 VPS13A TMEM63A	6.86e-05	184	103	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ARHGAP42 ABCC4 NEBL TOX3 ACOXL	7.04e-05	185	103	5	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPE POLA1 PAXBP1 CEBPZ DNMT1	7.22e-05	186	103	5	15ab6666748a641226e42e6ca6eeaf186a501c95
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPE POLA1 PAXBP1 CEBPZ DNMT1	7.22e-05	186	103	5	4ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated\|bone_marrow / Manually curated celltypes from each tissue	TPT1 HSPH1 BAG3 RPS27A CD2	7.22e-05	186	103	5	5108d9b7a081876ca34594b110d58df56063f542
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	ARHGAP42 ABCC4 NRP1 VPS13A BHMT2	7.40e-05	187	103	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	ITSN1 NEB NRP1 ARHGAP5 ARHGAP18	7.40e-05	187	103	5	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCC4 SATB2 NEBL SYNE1 RPS27A	7.98e-05	190	103	5	a5db902ad112a0c0a0a7f1a2e38718bb3bd11412
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP42 ABCC4 SATB2 TRIO NRP1	8.18e-05	191	103	5	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	HSPH1 RPS27A CD2 STAMBPL1 TMEM63A	8.38e-05	192	103	5	35557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCell	droplet-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASEH2B POLA1 HSPH1 MCM3 DNMT1	8.59e-05	193	103	5	40eedc1490c113403bc7c12a6bdf976f4f8bca84
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-22\|World / Primary Cells by Cluster	SATB2 CUX2 RPS27A NRP1 ARHGAP18	8.59e-05	193	103	5	3b927d4b8ecb21a408424ef91a23746c21741f49
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCC4 P2RY13 SULF2 STAMBPL1 DNMT1	8.80e-05	194	103	5	e56c6e5c9b7d287ae94566b561e21cec2055f83d
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CENPE POLA1 MCM3 SULF2 DNMT1	9.01e-05	195	103	5	c1435e61e4f0cf457f26ae436936048932ceb0db
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	TPT1 SYNE1 ITSN1 P2RY13 NRP1	9.01e-05	195	103	5	4008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ABCC4 P2RY13 SULF2 STAMBPL1 DNMT1	9.01e-05	195	103	5	85fee07d71c0393ea42bcf1130566dff4a62f507
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP42 ABCC4 FER1L6 TOX3 ACOXL	9.01e-05	195	103	5	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SATB2 CUX2 NEBL HSPH1 NBPF19	9.01e-05	195	103	5	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	metastatic_Lymph_Node-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	TPT1 REEP3 ATP10D CD2 ARHGAP18	9.01e-05	195	103	5	944158240cfc3b2cf72a6601b4e02d8d31a903b9
ToppCell	droplet-Thymus-nan-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASEH2B CENPE POLA1 MCM3 DNMT1	9.01e-05	195	103	5	043e2f19d95e94cd5219e2c415f322ed340aa80f
ToppCell	normal_Pleural_Fluid\|World / Location, Cell class and cell subclass	TPT1 SP100 RPS27A CD2 SULF2	9.23e-05	196	103	5	7029c9f4a826f6cfdcb5f7a472fba94e8945a771
ToppCell	Control-Neu_4\|Control / 5 Neutrophil clusters in COVID-19 patients	CEP104 BDP1 CENPE CRY1 VPS13A	9.23e-05	196	103	5	b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	TPT1 SYNE1 ITSN1 P2RY13 NRP1	9.23e-05	196	103	5	e8c4eeb4b6c6d9bccca2adb942d4cfbaab39636c
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RNASEH2B CUX2 HSPH1 SULF2 STAMBPL1	9.46e-05	197	103	5	8fa38fb95e285f9cc756ec4f32009be4ede09d3c
ToppCell	Mild\|World / Condition, Lineage, Cell class and cell subclass	BDP1 SP100 OTUB1 NCOR1 CD2	9.46e-05	197	103	5	476b0d0389f9fcd4614f6bb1f494281f467f6730
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN_to_DP_transition,_dividing_(more_DN)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASEH2B POLA1 MCM3 NRP1 DNMT1	9.46e-05	197	103	5	d9978aaa476b57144b0561f535ff1dd886c7512b
ToppCell	normal_Pleural_Fluid-T/NK_cells-Exhausted_CD8+_T\|T/NK_cells / Location, Cell class and cell subclass	CASP4 DBI NCOR1 CD2 ARHGAP18	9.46e-05	197	103	5	2bf540fa228687a71f595a807e4a2af20588a82c
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	BDP1 CENPE ZC3H13 EIF3J DNMT1	9.46e-05	197	103	5	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	myeloid-CD34+_Monoblast\|myeloid / Lineage and Cell class	RNASEH2B MCM3 DBI PDIA6 DNMT1	9.69e-05	198	103	5	e26b98a8380e693110a97d8e5a353998f8d67c6d
ToppCell	LPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC\|LPS_only / Treatment groups by lineage, cell group, cell type	CUX2 HSPH1 CCDC178 SULF2 STAMBPL1	9.69e-05	198	103	5	d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	CEP104 ZC3H13 HSPH1 SBNO1 ARHGAP18	9.92e-05	199	103	5	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	T_cells-CCR7+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	TPT1 HSPH1 BAG3 ARHGAP5 SCML1	9.92e-05	199	103	5	467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCell	Transverse-T_cell-Th1\|T_cell / Region, Cell class and subclass	TPT1 HSPH1 BAG3 NBPF19 CD2	9.92e-05	199	103	5	9271d9d36ffe1c169049d4340258f366916adfaf
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	KIZ ZC3H13 HSPH1 RPS27A SBNO1	9.92e-05	199	103	5	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	ZC3H13 HSPH1 RPS27A SBNO1 SECISBP2	9.92e-05	199	103	5	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-CD8+_Tcm\|ICU-NoSEP / Disease, condition lineage and cell class	TPT1 RPS27A ANKRD18B CD2 TMEM63A	9.92e-05	199	103	5	1df6d3dfb90e804cf65dc4dcb1c51d5974abfbab
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	SP100 ZC3H13 NCOR1 SBNO1 SECISBP2	9.92e-05	199	103	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SP100 SYNE1 RPS27A NCOR1 CD2	9.92e-05	199	103	5	8f2b57cf2f932f20ea029132d8bda01aac774571
ToppCell	Parenchyma_Control_(B.)-Immune-TX-TRAM-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ITSN1 HSPH1 BAG3 DDX60L ARHGAP18	1.02e-04	200	103	5	7c56935446f10d202eafa1f9ee7cb0aae4c2607e
ToppCell	PBMC-Severe-cDC_9\|Severe / Compartment, Disease Groups and Clusters	SP100 NT5C3A P2RY13 COA6 DDX60L	1.02e-04	200	103	5	ea3b22126d9dfd158bb3c3e1323b30514d721ded
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	CEP104 CENPE CRY1 NBPF9 VPS13A	1.02e-04	200	103	5	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte-\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CENPE POLA1 HSPH1 MCM3 DNMT1	1.02e-04	200	103	5	7e4c0db43a03ca11380a54f44a3cf1991e055b80
ToppCell	COVID_vent-Lymphocytic-Proliferative_Lymphocyte\|COVID_vent / Disease condition, Lineage, Cell class and subclass	CENPE POLA1 HSPH1 MCM3 DNMT1	1.02e-04	200	103	5	9775ca7dedb76fcbb74f80f86b33c94e394c320a
Drug	Picrotoxinin [17617-45-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A	ABCC4 SATB2 TRIO ITSN1 UTP14A PIAS4 TOX4 TMEM63A	2.57e-06	197	100	8	4842_DN
Disease	Endometrioma	ABCC4 CYP19A1 NRP1 NCOR1 SULF2 ARHGAP28	1.32e-05	161	94	6	C0269102
Disease	Endometriosis	ABCC4 CYP19A1 NRP1 NCOR1 SULF2 ARHGAP28	1.32e-05	161	94	6	C0014175
Disease	polycystic ovary syndrome (implicated_via_orthology)	CYP19A1 NCOR1	1.49e-04	6	94	2	DOID:11612 (implicated_via_orthology)
Disease	BMI-adjusted waist-hip ratio, forced expiratory volume	CUX2 CYP19A1	1.49e-04	6	94	2	EFO_0004314, EFO_0007788
Disease	IGF-1 measurement	CUX2 KIZ CMIP SBNO1 DDX60L EIF3J ACOXL DNMT1	1.70e-04	488	94	8	EFO_0004627
Disease	Hereditary Sensory Autonomic Neuropathy, Type 1	SPTLC1 DNMT1	2.78e-04	8	94	2	C0020071
Disease	Arthritis, Experimental	MMP3 IL33 DNMT1	2.84e-04	40	94	3	C0993582
Disease	Arthritis, Adjuvant-Induced	MMP3 IL33 DNMT1	2.84e-04	40	94	3	C0003865
Disease	Arthritis, Collagen-Induced	MMP3 IL33 DNMT1	2.84e-04	40	94	3	C0971858
Disease	hydroxy-leucine measurement	DAB2IP CCDC178 ALMS1	4.03e-04	45	94	3	EFO_0005276
Disease	response to docetaxel trihydrate, response to antineoplastic agent	DAB2IP ARHGAP18	5.42e-04	11	94	2	GO_0097327, GO_1902519
Disease	Malignant neoplasm of breast	SYNE1 CYP19A1 SPTLC1 NCOR1 CD2 SULF2 HOOK3 SBNO1 TOX3 MMP3 DNMT1	6.18e-04	1074	94	11	C0006142
Disease	glucose metabolism measurement, age-related hearing impairment	DAB2IP TPT1 INPP5A	6.18e-04	52	94	3	EFO_0005782, EFO_0009367
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 HOOK3	6.49e-04	12	94	2	DOID:11726 (implicated_via_orthology)
Disease	hematologic cancer (implicated_via_orthology)	CUX2 PIAS4	7.65e-04	13	94	2	DOID:2531 (implicated_via_orthology)
Disease	MAP kinase-activated protein kinase 3 measurement	ZC3H13 TOX4	7.65e-04	13	94	2	EFO_0008226
Disease	Prostatic Neoplasms	DAB2IP TPT1 ABCC4 CYP19A1 ITSN1 NRP1 NCOR1 DNMT1	7.95e-04	616	94	8	C0033578
Disease	Malignant neoplasm of prostate	DAB2IP TPT1 ABCC4 CYP19A1 ITSN1 NRP1 NCOR1 DNMT1	7.95e-04	616	94	8	C0376358
Disease	serum metabolite measurement	ABCC4 TRIO NT5C3A ATP10D PDIA6 ALMS1 BHMT2 CCDC180 IL33 DNMT1	8.62e-04	945	94	10	EFO_0005653
Disease	esophagus adenocarcinoma (is_implicated_in)	CYP19A1 MMP3	2.03e-03	21	94	2	DOID:4914 (is_implicated_in)
Disease	polycystic ovary syndrome (biomarker_via_orthology)	CYP19A1 NCOR1	2.03e-03	21	94	2	DOID:11612 (biomarker_via_orthology)
Disease	Joubert syndrome 1	CEP104 CEP41	2.03e-03	21	94	2	C4551568
Disease	Schizophrenia	TPT1 INPP5A CASP4 CMYA5 SBNO1 PPP1R9B MMP3 ARHGAP18 DNMT1	2.03e-03	883	94	9	C0036341
Disease	endometriosis (is_marker_for)	CYP19A1 DNMT1	2.87e-03	25	94	2	DOID:289 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKKLLQLKEKYYAIE	NT5C3A	121	Q9H0P0
KRETTESEKYIYEKK	BDP1	1451	A6H8Y1
ESEKYIYEKKSETKK	BDP1	1456	A6H8Y1
EAVKTDGKKSYYKKV	DNMT1	736	P26358
EKKKYYDAKTEDKVR	CASP4	41	P49662
FRKEKETFKEKDTYK	CD2	71	P06729
KKREEEKRKSEYKSY	ALMS1	4131	Q8TCU4
EKLEEIKKNYRYKKD	CEP41	41	Q9BYV8
IKKNYRYKKDELFKR	CEP41	46	Q9BYV8
YAIKNDSLRKEKKYI	ANKRD18B	351	A2A2Z9
LQWKKKIYKYKKVLS	CMIP	156	Q8IY22
EKVKDYLKNMKSRYE	CCDC180	586	Q9P1Z9
DMKKLEKKAYLKRRY	CUX2	1121	O14529
ITKVYSRKEKKYIDR	ATP10D	156	Q9P241
VARIYYKVKTKKEDF	ACOXL	451	Q9NUZ1
YRETDKKKKKERNSY	DAB2IP	276	Q5VWQ8
LKKLYDVVDVKYKRN	GDAP2	406	Q9NXN4
KLLKDKITQYEKSLY	EIF3J	161	O75822
AEFKTKYKLDAKSKI	HSPH1	246	Q92598
YYDLKKDVKQFVRRK	MMP3	41	P08254
KAEKLERKKVYRAEY	DDX60L	1171	Q5H9U9
IRKKSKYESEIKYLT	CCDC178	471	Q5BJE1
YFYKKTSRDHKKKLK	KIF27	1211	Q86VH2
DFKAKKYRKVAGKEI	INPP5A	121	Q14642
TYEKTYKKTNKEKFR	MORC3	461	Q14149
YSLKYTKYTKKDTKK	CYLC1	276	P35663
AINVSKARKKYKVEY	MGST3	26	O14880
SYSKKIVKLLKKEYK	PAXBP1	126	Q9Y5B6
YLCKEKKKTEKSLTY	TMEM63A	271	O94886
EERYKKYLEKAKSVI	HOOK3	601	Q86VS8
RVKLKYVKLKNYLKE	KIZ	51	Q2M2Z5
KKYKYEECKDLIKFM	NBPF1	56	Q3BBV0
ERLKKAKAGEKYKYE	POLA1	36	P09884
IAKKVYDSYRKSKSK	P2RY13	231	Q9BPV8
YAYFKKVLEKEKKRK	MCM3	651	P25205
GKKYEKERYEKVIKA	ABCC4	496	O15439
SKETKKKYYVKTYKI	NRP1	346	O14786
KLKIITYRNLFKKVY	PCID2	316	Q5JVF3
KIKDLHKKYSYIRKT	OTUB1	71	Q96FW1
KREAVQKERYDYAKK	CEP104	221	O60308
KKDEKKDKVLLSYYE	IL33	151	O95760
TSIYKYQKDEARIKK	BHMT2	116	Q9H2M3
YKKYEKSVKDLKDAI	CYP19A1	241	P11511
FEYRKKEGEKIRKKY	GABARAPL1	11	Q9H0R8
KEKSYTGIYDKARKK	CMYA5	181	Q8N3K9
ELYIETEKKKREKAY	ITSN1	1571	Q15811
YFKLTDLYKKVKKNS	CRY1	266	Q16526
FEYRKKEGEKIRKKY	GABARAPL3	11	Q9BY60
MKAYINKVEELKKKY	DBI	71	P07108
QLELKKSKRKDYYKI	DNAJC7	371	Q99615
KSKRKDYYKILGVDK	DNAJC7	376	Q99615
YFTYEELKDIKKKVI	FBXL5	141	Q9UKA1
KTDKKYLMIEEYLTK	BAG3	446	O95817
QLKLEIYADLKKKYK	SBNO1	1241	A3KN83
IYADLKKKYKKVVSD	SBNO1	1246	A3KN83
KKLKYVLSYVTKIKE	CENPE	2171	Q02224
RYYKKVAVKEKQKRD	CEBPZ	816	Q03701
YLEVLLKLADKYKKK	PDIA6	316	Q15084
VVKYRVYTLKKLQAK	NAP1L6P	46	A6NFF2
YKTEKYVIAKNKKVG	P2RX5	16	Q93086
LIYLIKKREFYRDKK	P2RX5	336	Q93086
KYYASLKKAQKAKER	FER1L6	1216	Q2WGJ9
IADKKRKKYLNNKYR	RPE65	291	Q16518
YKKHSYRLVKKLKLQ	SCML1	106	Q9UN30
KMELYEKKAQLSKYK	SYNE1	3846	Q8NF91
KKYKYEECKDLIKFM	NBPF9	56	P0DPF3
KKYKYEECKDLIKFM	NBPF10	56	Q6P3W6
QKKYKYEECKDLIKF	NBPF10	326	Q6P3W6
KKYKYEECKDLIKFM	NBPF11	56	Q86T75
KKYKYEECKDLIKFM	NBPF12	56	Q5TAG4
KKYKYEECKDLIKFM	NBPF15	56	Q8N660
KKYKYEECKDLIKFM	NBPF19	56	A0A087WUL8
KKKFDKESEKYYSIL	ARHGAP42	131	A6NI28
RKAKESKTREYYEKQ	NCOR1	331	O75376
YKKYKKIKVERVERE	SATB2	226	Q9UPW6
ALFKKKTYDEKKTYD	SECISBP2	141	Q96T21
KLLSEKKLKRYFVDY	MTG2	61	Q9H4K7
EYRSKIDAKYKKKIE	WDR19	1221	Q8NEZ3
SKYKYKSKTLFSKAK	ARHGAP5	1151	Q13017
KEVRYGSLKYKVKKR	REEP3	236	Q6NUK4
VKLKYKYKARIFLEE	SPTLC1	261	O15269
KYFDKRRDYLKFKEK	COA6	96	Q5JTJ3
KVKQYKELYKKKLTS	VPS13A	361	Q96RL7
DNKKYYKYSKEKTLK	RNASEH2B	151	Q5TBB1
YKYSKEKTLKWLEKK	RNASEH2B	156	Q5TBB1
YSKLYKEAEKIKKWK	SYCP1	106	Q15431
KKSEIKKEDYVLTKF	ARHGAP28	306	Q9P2N2
YLQSKNKYKAEILKK	STAMBPL1	136	Q96FJ0
QFYEKKAAKLKEKYK	SP100	816	P23497
KEKYKKDIAAYRAKG	SP100	826	P23497
EAYKKYIKDYMKSIK	TPT1	86	P13693
KNKIKVYIYALKKYV	EXT2	101	Q93063
EKYKSSRKLIDQAYK	TBC1D3E	86	A0A087X179
YYEAKARREKKIKSK	UTP14A	236	Q9BVJ6
KQVYKRKTEAAKKEY	TOX3	301	O15405
VKKIKEFKSAYFKSI	PKD2L2	301	Q9NZM6
LLKKMAYDREKYEKQ	ARHGAP18	551	Q8N392
KKIKELYETRYAKKN	PIAS4	56	Q8N2W9
FKRSYNYKTIVKKIL	ZNF770	326	Q6IQ21
RDKTEFAQDKYIKKK	TRMT6	136	Q9UJA5
YIKKKKKKYEAIITV	TRMT6	146	Q9UJA5
DKKKSTKDRYEEYKE	ZNF852	121	Q6ZMS4
KKKSTKDRYDKYKEV	ZKSCAN7	346	Q9P0L1
KKVKLAVLKYYKVDE	RPS27A	96	P62979
KYLKYLYTKEKVKKA	TRMT10C	131	Q7L0Y3
KLFKKKYKASYVRSR	SULF2	521	Q8IWU5
VYKRKTEAAKKEYLK	TOX4	271	O94842
LGKKYKEKYKVKDRI	ZC3H13	276	Q5T200
KYQLLLKDFLKYSKK	TRIO	2106	O75962
LERKYSKAKRLIKDY	PPP1R9B	751	Q96SB3
KYITNLLREKEYKKD	NEBL	401	O76041
YTDKARKMRDKYKVV	NEB	5126	P20929
LQSIVKYKEKYEKER	NEB	5896	P20929