Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	anophthalmia	FOXD4L4 ELOA2 FOXD4L1 MYCBP2 FOXD4L3 FOXD4L6 MMP15 FOXD4L5 FOXD4	4.03e-06	246	71	9	MP:0001293
MousePheno	increased oxygen consumption	NCOR1 MARK4 C1QTNF2 ZNF217 ARHGEF11 DGAT1	3.36e-05	121	71	6	MP:0005289
Domain	TF_fork_head_CS_2	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	7.93e-08	46	89	6	IPR030456
Domain	TF_fork_head_CS_1	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	9.06e-08	47	89	6	IPR018122
Domain	FH	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.17e-07	49	89	6	SM00339
Domain	FORK_HEAD_1	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.17e-07	49	89	6	PS00657
Domain	FORK_HEAD_2	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.17e-07	49	89	6	PS00658
Domain	Fork_head_dom	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.17e-07	49	89	6	IPR001766
Domain	FORK_HEAD_3	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.17e-07	49	89	6	PS50039
Domain	Forkhead	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.17e-07	49	89	6	PF00250
Domain	-	FOXD4L4 FOXD4L1 FOXD4L3 IRF3 FOXD4L6 FOXD4L5 FOXD4	8.21e-05	218	89	7	1.10.10.10
Domain	WHTH_DNA-bd_dom	FOXD4L4 FOXD4L1 FOXD4L3 IRF3 FOXD4L6 FOXD4L5 FOXD4	1.57e-04	242	89	7	IPR011991
Domain	NUT	NUTM2F NUTM2G	2.22e-04	5	89	2	IPR024310
Domain	NUT_N	NUTM2F NUTM2G	2.22e-04	5	89	2	IPR024309
Domain	NUT	NUTM2F NUTM2G	2.22e-04	5	89	2	PF12881
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	2.53e-16	6	90	6	27092474
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	7.07e-15	8	90	6	8530406
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	2.12e-14	9	90	6	12412011
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	4.29e-13	13	90	6	16884697
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	4.29e-13	13	90	6	7957066
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.24e-12	15	90	6	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.24e-12	15	90	6	22045912
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.99e-12	16	90	6	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.99e-12	16	90	6	10208738
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	6.69e-12	19	90	6	9895322
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	9.54e-12	20	90	6	12812790
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.33e-11	21	90	6	9449667
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.83e-11	22	90	6	17389379
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	3.29e-11	24	90	6	11820816
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	3.29e-11	24	90	6	29992973
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	5.60e-11	26	90	6	15857913
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.15e-10	29	90	6	22972626
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L4 FOXD4L6 FOXD4L5 FOXD4	2.09e-10	5	90	4	12234674
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NCOR1 ABCA2 ARID3A MYCBP2 MYO9B NISCH TMCC2 MARK4 FBRSL1 CACNA1H EDC4 ANKHD1 ARHGEF11 TTC3 CIC IFNLR1 FAM83H	3.20e-09	1105	90	17	35748872
Pubmed	Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	1.36e-08	11	90	4	12421752
Pubmed	Genome-scale study of transcription factor expression in the branching mouse lung.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	2.23e-08	67	90	6	22711520
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NCOR1 KIFBP SETX ARID3A FOXD4L1 CMTR1 MYO9B NISCH IRF3 ANKHD1 CIC CUX1 FOXD4 HMG20B	4.38e-08	857	90	14	25609649
Pubmed	Diverse fates of paralogs following segmental duplication of telomeric genes.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4	2.96e-07	22	90	4	15233989
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 CIC FOXD4L5 FOXD4 HMG20B	4.36e-07	263	90	8	20932939
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXD4L4 ARID3A FOXD4L1 FOXD4L3 ZNF217 FOXD4L6 CIC CUX1 FOXD4L5 FOXD4 HMG20B	2.26e-06	709	90	11	22988430
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DNAJB11 ZNF469 PTPN14 MAPT MARK4 FBRSL1 RAB11FIP5 VAX2 CSMD1 ANKHD1 FAM83H HMG20B ZNF646	5.95e-06	1116	90	13	31753913
Pubmed	High frequency of matrix attachment regions and cut-like protein x/CCAAT-displacement protein and B cell regulator of IgH transcription binding sites flanking Ig V region genes.	ARID3A CUX1	6.62e-06	2	90	2	12193717
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOR1 KIFBP FAM171A2 MYCBP2 NISCH EIF4A2 ZSCAN18 EDC4 ARHGEF11 TTC3 CUX1 CRMP1	7.16e-06	963	90	12	28671696
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIFBP ABCA2 SETX MDC1 FBRSL1 RAB11FIP5 SNRK ANKHD1 ZNF646	9.65e-06	529	90	9	14621295
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOR1 PTPN14 SETX MYO9B FBRSL1 RAB11FIP5 ZNF217 CIC DDX11	2.22e-05	588	90	9	38580884
Pubmed	Interaction network of human early embryonic transcription factors.	NCOR1 ARID3A MDC1 NAB2 FBRSL1 ZNF217 HMG20B	3.66e-05	351	90	7	38297188
Pubmed	DOK3 is required for IFN-β production by enabling TRAF3/TBK1 complex formation and IRF3 activation.	DOK3 IRF3	6.59e-05	5	90	2	24929003
Pubmed	Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain.	MAPT CRMP1	6.59e-05	5	90	2	15834957
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOR1 ARID3A CIC CUX1	6.59e-05	83	90	4	28794006
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOR1 MDC1 ZNF217 CIC CUX1 HMG20B	7.17e-05	268	90	6	33640491
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PTPN14 SETX FAM171A2 MYCBP2 MAPT MARK4 RAB11FIP5 EDC4 CIC FAM83H	7.87e-05	861	90	10	36931259
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	ABCA2 DCAF10 NISCH TMCC2 MDC1 MARK4 CACNA1H DGAT1 SLC45A4	8.25e-05	697	90	9	28298427
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOR1 PTPN14 MYCBP2 MDC1 NAA30 EDC4 ANKHD1 CUX1	9.14e-05	549	90	8	38280479
Pubmed	Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.	MAPT MARK4	9.87e-05	6	90	2	23666762
Pubmed	Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System.	MAPT CACNA1H	9.87e-05	6	90	2	28360836
Pubmed	Homeostatic interferon-lambda response to bacterial microbiota stimulates preemptive antiviral defense within discrete pockets of intestinal epithelium.	IRF3 IFNLR1	9.87e-05	6	90	2	35137688
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	NCOR1 MYCBP2 ZNF217 ANKHD1 CIC CUX1 HMG20B	1.09e-04	418	90	7	34709266
Pubmed	Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss.	MAPT TTC3 CUX1	1.22e-04	37	90	3	26951610
Pubmed	MST1-dependent vesicle trafficking regulates neutrophil transmigration through the vascular basement membrane.	MST1L SYTL1	1.38e-04	7	90	2	27701149
Pubmed	Cochlear histopathology of the mutant bustling mouse, BUS/Idr.	CDH23 MOS	1.38e-04	7	90	2	8790740
Pubmed	Biological insights from 108 schizophrenia-associated genetic loci.	NISCH NAB2 C16orf86 EDC4 CSMD1 SNX19	1.40e-04	303	90	6	25056061
Pubmed	Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	1.48e-04	306	90	6	18973680
Pubmed	Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ZNF469 MARK4 CDH23 FBN3	1.77e-04	107	90	4	11347906
Pubmed	Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.	IRF3 IFNLR1	1.84e-04	8	90	2	24278020
Pubmed	An innate antiviral pathway acting before interferons at epithelial surfaces.	IRF3 IFNLR1	1.84e-04	8	90	2	26595890
Pubmed	Two quantitative trait loci affecting progressive hearing loss in 101/H mice.	CDH23 CACNA1H	1.84e-04	8	90	2	16897347
Pubmed	Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth.	MAPT CUX1	2.36e-04	9	90	2	16387638
Pubmed	N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.	DOK3 SNRK MON1B SYTL1 SLC45A4	2.58e-04	217	90	5	34048709
Pubmed	Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes.	TMCC2 MARK4 CRMP1	2.83e-04	49	90	3	19019082
Pubmed	ADF/cofilin-mediated actin retrograde flow directs neurite formation in the developing brain.	MAPT CUX1	2.94e-04	10	90	2	23259946
Pubmed	BIG1 is required for the survival of deep layer neurons, neuronal polarity, and the formation of axonal tracts between the thalamus and neocortex in developing brain.	MAPT CUX1	2.94e-04	10	90	2	28414797
Pubmed	Human transcription factor protein interaction networks.	NCOR1 ARID3A MDC1 ZSCAN18 FBRSL1 IRF3 ZNF217 EDC4 ANKHD1 CIC CUX1 HMG20B	3.13e-04	1429	90	12	35140242
Pubmed	Proteomic analysis of in vivo phosphorylated synaptic proteins.	MAPT RAB11FIP5 GPRIN3	3.57e-04	53	90	3	15572359
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	NCOR1 DNAJB11 PTPN14 FAM171A2 MYCBP2 RAB11FIP5 GPRIN3 C2CD4C SNX19 CIC	3.85e-04	1049	90	10	27880917
Pubmed	CAMSAP1 breaks the homeostatic microtubule network to instruct neuronal polarity.	MAPT CUX1	4.30e-04	12	90	2	32839317
Pubmed	Regulation of LSD1 histone demethylase activity by its associated factors.	ZNF217 HMG20B	4.30e-04	12	90	2	16140033
Pubmed	An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation.	ZNF217 HMG20B	5.07e-04	13	90	2	16079794
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NCOR1 SETX ARID3A MYCBP2 NAB2 ZNF217 EDC4 CIC CUX1 HMG20B	5.69e-04	1103	90	10	34189442
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	NIBAN1 MYCBP2 TAGAP CSMD1 IFNLR1	6.41e-04	265	90	5	19240061
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TSPOAP1 NISCH RHOBTB2 MARK4 CACNA1H SNX19	6.74e-04	407	90	6	12693553
Pubmed	Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis.	MAPT CSMD1	6.80e-04	15	90	2	23583980
Pubmed	C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development.	MAPT CUX1	6.80e-04	15	90	2	27111087
Pubmed	MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes.	MAPT MARK4	7.76e-04	16	90	2	14594945
Pubmed	Genome-wide association analysis of age-at-onset in Alzheimer's disease.	RNFT2 ALPK3	8.78e-04	17	90	2	22005931
Pubmed	Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.	CDS1 MMP15 DGAT1 SLC45A4	8.89e-04	164	90	4	22967998
Pubmed	The functional interactome landscape of the human histone deacetylase family.	NCOR1 DNAJB11 MYCBP2 ZNF217 HMG20B	9.46e-04	289	90	5	23752268
Pubmed	A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.	ZNF217 HMG20B	9.86e-04	18	90	2	12493763
Pubmed	LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.	MAPT CUX1	1.10e-03	19	90	2	17482548
Pubmed	Coronavirus subverts ER-phagy by hijacking FAM134B and ATL3 into p62 condensates to facilitate viral replication.	DNAJB11 FAM8A1	1.10e-03	19	90	2	36952345
Pubmed	Functional Cooperation of α-Synuclein and Tau Is Essential for Proper Corticogenesis.	MAPT CUX1	1.10e-03	19	90	2	35906071
Pubmed	Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration.	MAPT CUX1	1.22e-03	20	90	2	25535916
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	NIBAN1 RNFT2 UMODL1 RP1L1 SNRK ZNF217 CSMD1 C2CD4C	1.25e-03	814	90	8	23251661
Pubmed	KIF2A deficiency causes early-onset neurodegeneration.	MAPT CUX1	1.35e-03	21	90	2	36343267
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOR1 DNAJB11 ELOA2 FBRSL1 RAB11FIP5 CIC CUX1	1.36e-03	638	90	7	31182584
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	ABCA2 CSMD1 FBN3	1.37e-03	84	90	3	15203218
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	ZNF469 CACNA1H GPR101 CUX1	1.44e-03	187	90	4	26460568
Pubmed	BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.	NCOR1 FBRSL1	1.76e-03	24	90	2	33722704
Pubmed	CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism.	DNAJB11 KIFBP ANKHD1 CCS	1.88e-03	201	90	4	34917906
Pubmed	Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.	CIC CUX1	1.91e-03	25	90	2	28288114
Pubmed	Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.	NISCH CUX1	1.91e-03	25	90	2	29311744
Pubmed	Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	MYCBP2 RAB11FIP5 MON1B	2.26e-03	100	90	3	10048485
Pubmed	Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.	NISCH CCS SLC45A4	2.39e-03	102	90	3	21926972
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ARHGEF11 CIC ZNF646	2.53e-03	104	90	3	9205841
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	NCOR1 ABCA2 ANKHD1	2.53e-03	104	90	3	10470851
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	KIFBP NISCH EDC4 MOS FAM83H	2.57e-03	363	90	5	25036637
Interaction	TBR1 interactions	NCOR1 MYCBP2 FBRSL1 ZNF217 CIC HMG20B	8.88e-06	113	86	6	int:TBR1
Interaction	TBXT interactions	NCOR1 ARID3A FBRSL1 CIC CUX1 HMG20B	1.03e-05	116	86	6	int:TBXT
Interaction	TOP3B interactions	NCOR1 ABCA2 ARID3A MYCBP2 MYO9B NISCH EIF4A2 TMCC2 MDC1 MARK4 FBRSL1 CACNA1H EDC4 ANKHD1 ARHGEF11 TTC3 CIC IFNLR1 FAM83H	1.08e-05	1470	86	19	int:TOP3B
Interaction	PAX7 interactions	NCOR1 ARID3A FBRSL1 ZNF217 CIC HMG20B	1.51e-05	124	86	6	int:PAX7
Interaction	LCN15 interactions	SETX ARID3A MYO9B	1.61e-05	12	86	3	int:LCN15
Interaction	PPP2R1A interactions	PTPN14 MYCBP2 MAPT RHOBTB2 MARK4 ZSCAN18 RAB11FIP5 FOXD4L6 NABP1 CIC CFAP410 FOXD4	2.47e-05	665	86	12	int:PPP2R1A
Interaction	FEV interactions	NCOR1 ARID3A FBRSL1 ZNF217 CIC CUX1 HMG20B	2.60e-05	203	86	7	int:FEV
Interaction	TLX2 interactions	NCOR1 ARID3A FBRSL1 CIC CUX1 HMG20B	3.26e-05	142	86	6	int:TLX2
Interaction	RFXANK interactions	KIFBP SETX NAB2 VAX2 ANKHD1 ARHGEF11	3.81e-05	146	86	6	int:RFXANK
Interaction	SOX6 interactions	NCOR1 FBRSL1 ZNF217 CIC CUX1 HMG20B	5.71e-05	157	86	6	int:SOX6
Interaction	MDFI interactions	FOXD4L1 FOXD4L3 EIF4A2 NAB2 DOK3 ZNF696 FOXD4L6 FOXD4 ZNF646	9.08e-05	430	86	9	int:MDFI
Interaction	TLX1 interactions	NCOR1 ARID3A FBRSL1 ZNF217 CIC CUX1	1.04e-04	175	86	6	int:TLX1
Interaction	TEAD1 interactions	NCOR1 ARID3A FBRSL1 ZNF217 CIC CUX1	1.07e-04	176	86	6	int:TEAD1
Cytoband	9q21.11	FOXD4L4 FOXD4L3 FOXD4L6 FOXD4L5	3.64e-07	30	90	4	9q21.11
Cytoband	8q24.3	ZNF696 DGAT1 FAM83H SLC45A4	7.55e-05	113	90	4	8q24.3
Cytoband	2p13	RAB11FIP5 VAX2	9.36e-04	23	90	2	2p13
Coexpression	MORI_MATURE_B_LYMPHOCYTE_UP	FOXD4L4 FOXD4L1 MYCBP2 FOXD4L3 FOXD4L6 FOXD4L5 FOXD4	7.60e-08	106	89	7	MM595
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	CDS1 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 CSMD1 FOXD4L5 FOXD4	7.71e-07	217	89	8	MM861
Coexpression	ASTON_MAJOR_DEPRESSIVE_DISORDER_DN	ABCA2 MAPT MYO9B MDC1 SNX19 DDX11	1.80e-05	160	89	6	M11011
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	CMTR1 MYO9B FBRSL1 ARHGEF11 CIC CFAP410 ZNF646 DDX11	2.01e-05	338	89	8	M17094
Coexpression	VERHAAK_GLIOBLASTOMA_PRONEURAL	RNFT2 MAPT VAX2 TTC3 MMP15 CRMP1	3.18e-05	177	89	6	M2115
Coexpression	MEISSNER_BRAIN_HCP_WITH_H3K27ME3	FOXD4L4 FOXD4L1 FOXD4L3 VAX2 FOXD4L6 FOXD4L5 FOXD4	5.03e-05	282	89	7	MM822
Coexpression	GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_UP	MYO9B RHOBTB2 SNRK TTC3 CIC HMG20B	6.29e-05	200	89	6	M7746
Coexpression	GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_UP	MYCBP2 NISCH NAB2 IRF3 MMP15 CIC	6.29e-05	200	89	6	M8514
Coexpression	GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_UP	HDGFL1 TMCC2 ALPK3 C1QTNF2 CCS	7.96e-05	129	89	5	M464
Coexpression	GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_DN	CDS1 DCAF10 TSPOAP1 C2CD4C CRMP1	8.26e-05	130	89	5	M6087
ToppCell	wk_15-18-Hematologic-Myeloid-aDC_1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 NABP1 FOXD4L5 FOXD4	7.35e-08	177	90	7	ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCell	wk_20-22-Hematologic-Myeloid-aDC_1\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	NIBAN1 FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 NABP1 FOXD4	7.64e-08	178	90	7	fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FOXD4L4 FOXD4L1 FOXD4L3 TMCC2 FOXD4L5 FOXD4	1.78e-06	180	90	6	32d871738a24071b70084a7e80148a516110c78b
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_10\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FOXD4L4 FOXD4L1 FOXD4L3 TMCC2 FOXD4L5 FOXD4	1.78e-06	180	90	6	067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-CD4-positive,_alpha-beta_memory_T_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NIBAN1 MARK4 ZNF696 ZNF217 NUTM2F	9.32e-06	139	90	5	7c02caed5b9baf233bd6fb9a453708b3e157c790
ToppCell	COVID-19_Mild-Neu_0\|World / 5 Neutrophil clusters in COVID-19 patients	TSPOAP1 TMCC2 ALPK3 CSMD1 FBN3	9.65e-06	140	90	5	93f024473b1bb3bf93ae776fd6a8fc5e93d013f0
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXD4L4 FOXD4L1 FOXD4L3 FOXD4L6 FOXD4	2.33e-05	168	90	5	6dd58fd981750da49afd53796f244e1803cce97f
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIFBP CMTR1 MDC1 EDC4 CCS	2.39e-05	169	90	5	c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOK3 CDH23 RAB11FIP5 CSMD1 ARHGEF11	2.39e-05	169	90	5	e3100eb587005e160bd0b7990fa57ec49765133d
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	KIFBP CMTR1 MDC1 EDC4 CCS	2.39e-05	169	90	5	ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	KIFBP CMTR1 MDC1 EDC4 CCS	2.53e-05	171	90	5	26b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	CMTR1 MYCBP2 GPRIN3 TTC3 CRMP1	4.40e-05	192	90	5	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; MCF7; HT_HG-U133A	NCOR1 MYO9B MARK4 CACNA1H ARHGEF11 MMP15 CIC CFAP410	9.06e-07	193	89	8	3262_UP
Drug	Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Down 200; 5.8uM; MCF7; HT_HG-U133A	ABCA2 MYO9B RHOBTB2 MARK4 RAB11FIP5 ARHGEF11 CFAP410	1.19e-05	196	89	7	6846_DN
Drug	LY 294002; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAPT MYO9B MARK4 RAB11FIP5 ARHGEF11 MMP15 CIC	1.28e-05	198	89	7	6976_UP
Disease	reticulocyte count	ZNF469 ARID3A DCAF10 MAPT MYO9B NISCH TMCC2 MARK4 SOWAHD ZNF217 NABP1 CUX1 SLC45A4	5.16e-06	1045	81	13	EFO_0007986
Disease	immature platelet fraction	MYO9B TMCC2 MARK4 NABP1 CUX1	1.60e-05	114	81	5	EFO_0009187
Disease	reticulocyte measurement	ZNF469 ARID3A MAPT MYO9B NISCH TMCC2 MARK4 SOWAHD ZNF217 NABP1 CUX1 SLC45A4	2.93e-05	1053	81	12	EFO_0010700
Disease	Parkinson disease	FAM171A2 MYCBP2 MAPT FBRSL1 GPRIN3 ZNF646 DDX11	2.95e-05	321	81	7	MONDO_0005180
Disease	age at diagnosis, osteoarthritis	MAPT RP1L1	1.55e-04	7	81	2	EFO_0004918, MONDO_0005178
Disease	immature platelet count	TMCC2 MARK4 NABP1 CUX1	2.12e-04	106	81	4	EFO_0803544
Disease	immature platelet measurement	MYO9B TMCC2 MARK4 NABP1	3.29e-04	119	81	4	EFO_0803541
Disease	neutrophil count	PTPN14 MYCBP2 TAGAP TSPOAP1 MAPT TMCC2 RP1L1 MARK4 CDH23 NABP1 CIC SLC45A4	3.77e-04	1382	81	12	EFO_0004833
Disease	Psoriasis	TAGAP CSMD1 IFNLR1	5.24e-04	57	81	3	C0033860
Disease	Pustulosis of Palms and Soles	TAGAP CSMD1 IFNLR1	5.24e-04	57	81	3	C0030246
Disease	Malignant neoplasm of breast	NCOR1 CDS1 PTPN14 NISCH EIF4A2 OXSM TTC3 CIC CUX1 ZNF646	7.07e-04	1074	81	10	C0006142
Disease	progranulin measurement	FAM171A2 CDH23	1.66e-03	22	81	2	EFO_0004625
Disease	platelet measurement	MYO9B TMCC2 MARK4 NABP1 CUX1	1.77e-03	315	81	5	EFO_0005036
Disease	basal cell carcinoma	RHOBTB2 TMCC2 FBRSL1 CUX1	1.85e-03	189	81	4	EFO_0004193
Disease	mean platelet volume	NIBAN1 MYO9B TMCC2 MARK4 FBRSL1 ZNF217 NABP1 CUX1 SLC45A4	1.91e-03	1020	81	9	EFO_0004584
Disease	methionine measurement	ZNF696 ANKHD1	2.32e-03	26	81	2	EFO_0009771

Protein segments in the cluster

Peptide	Gene	Start	Entry
RSEGEPPHAEAGLGA	UMODL1	1256	Q5DID0
RGEDEASEPPAGGLH	FBRSL1	861	Q9HCM7
GEEGPGPELHSGCLD	C6orf136	91	Q5SQH8
ITAAPEREGTGHGGP	CFAP410	141	O43822
GEEPGGLPSLGVSDH	C16orf86	271	Q6ZW13
AVSPPHREGEAAGGD	CDS1	16	Q92903
GDPGTPAHGSRLGDD	CSMD1	2921	Q96PZ7
ARDDDHEGGPVEGPG	CUX1	1386	P39880
TGHEQAGREPGPGSS	ALPK3	66	Q96L96
HGEPEPEELPGGTGS	ARHGEF11	1121	O15085
GHGAVPGPDDSREDV	FBN3	2071	Q75N90
PSSHGGGGPAAAEEE	DGAT1	16	O75907
PEPGPESGQARGEHT	C2CD4C	286	Q8TF44
ELDEEPGDHSPGQGS	CDH23	3251	Q9H251
GPVGFGPGDRSHLDS	RBM42	121	Q9BTD8
DGSSRPVGGTDPEGA	TSPOAP1	66	O95153
GASHPGEEEGARLPE	RAB11FIP5	416	Q9BXF6
DGGPGDGDRHNTPSL	EDC4	796	Q6P2E9
GGGHLDSEGEEAPRP	GOLGA8S	421	H3BPF8
ALPGEGDGGGHLDSE	GOLGA8F;	216	Q08AF8
GGGVHAVPPDPEDEG	MON1B	31	Q7L1V2
GLSGDAGHITAPDPE	OXSM	306	Q9NWU1
AGHITAPDPEGEGAL	OXSM	311	Q9NWU1
DGRDPGNGTHGLSPE	ELOA2	321	Q8IYF1
SDEEGHSPVLGGLGP	MDC1	196	Q14676
EDKPTHAGGGGDELG	HDGFL1	116	Q5TGJ6
APGHSEAGGVDSGRP	IFNLR1	356	Q8IU57
GGELLPDPDGDSHGP	MST1L	431	Q2TV78
PGRSTPESDVGAGGE	NAB2	186	Q15742
REHIEGGGGPSDPSE	FOXD4L4	71	Q8WXT5
REHIEGGGGPSDPSE	FOXD4L3	71	Q6VB84
GPGLGGDTHFDADEP	MMP15	226	P51511
HDGDRGDSGEEGPPG	C1QTNF2	71	Q9BXJ5
TGSRPAGEEDAGGPE	FDX2	51	Q6P4F2
GDGSAGAGAEEPTPH	DCAF10	11	Q5QP82
HGGEPEPHEGPGSRS	DOK3	411	Q7L591
EDSHPDLPGTEGGTE	GPR101	481	Q96P66
PREGSGGEPVHEGRQ	DDX11	826	Q96FC9
PREHIEGGGGPSDPS	FOXD4	66	Q12950
SAEGPGGLEPGLEEH	FAM171A2	446	A8MVW0
DEGEDDLGRGGHPLS	CCS	201	O14618
DVLPGAEGPASGEGH	ABCA2	1341	Q9BZC7
GEGEPHVDGEPGDLR	DNAJB11	226	Q9UBS4
EHGGPEGMDPDGVIE	EIF4A2	11	Q14240
GGAGGPEPLSHFEVE	MARK4	701	Q96L34
REHIEGGGPSDPSEF	FOXD4L1	71	Q9NU39
LPGEGHGGEHLDSEG	GOLGA8R	421	I6L899
SSPGAGEGPAEEGTR	FAM83H	1146	Q6ZRV2
HSSSPVGGPEGERQG	GPRIN3	211	Q6ZVF9
EPHGPEASPVAGGER	CACNA1H	2116	O95180
GITGPEGHALSRPEE	CRMP1	216	Q14194
PEAEDGPGAGDHALG	KIFBP	61	Q96EK5
GEGGIDGDGDITRPE	CMTR1	326	Q8N1G2
DDGGGDHEPVPSLRG	FAM8A1	16	Q9UBU6
SEELLPNSGHGPDGE	IRF3	296	Q14653
GHPEGDAGEPHCRTG	MOS	156	P00540
EGPRAGEKGSHEEEP	HMG20B	36	Q9P0W2
LGSHPGDTGEPEGQR	NUTM2F	406	A1L443
LGSHPGDTGEPEGQR	NUTM2G	391	Q5VZR2
GHSEEGGDEQPGTPA	RNFT2	136	Q96EX2
AGSEGAGLPPSGELH	SYTL1	411	Q8IYJ3
GPVGNGVHTGPESRE	NABP1	146	Q96AH0
PAGHGDTDGPISLDV	TMCC2	261	O75069
SGDSLGHVSGPGRPE	TAGAP	676	Q8N103
REHIEGGGGPSDPSE	FOXD4L5	71	Q5VV16
REHIEGGGGPSDPSE	FOXD4L6	71	Q3SYB3
APQGGAEDEEGPRGH	GPR150	376	Q8NGU9
ETRREEGDPSPHSGG	NCOR1	2306	O75376
LREQGPPEEGSGSHE	PTPN14	671	Q15678
SEGELGGPSEPGGTH	RHOBTB2	301	Q9BYZ6
GGPSEPGGTHPEDHQ	RHOBTB2	306	Q9BYZ6
SEDPLGGGDPTARHI	SETX	1461	Q7Z333
GPDGGDHETDGDLLA	MYCBP2	1286	O75592
EERAEELGGPSGPGS	SOWAHD	91	A6NJG2
RRDSSEGPPGSEGDG	SNRK	566	Q9NRH2
SPGRGREGPGEEHFE	ARID3A	101	Q99856
RGVFPEGEGDGSLPE	ANKHD1	876	Q8IWZ3
ESAAVAHERPPGGTG	CIC	76	Q96RK0
AEEPGALDGGEPHGV	SLC45A4	266	Q5BKX6
HGEELGGFPEVGSPA	NIBAN1	781	Q9BZQ8
GLRGPEVDPGDDHSL	RP1L1	986	Q8IWN7
PGAVGGASPEHAEPE	NISCH	561	Q9Y2I1
TEPAAEAGAPEGEGH	ZNF696	46	Q9H7X3
REGLASHPGPEDGAD	ZNF646	171	O15015
HPELLPESSGDDGQG	TTC3	1741	P53804
SGTGPEDTEGGRHAP	MAPT	171	P10636
GSAGPSPEVEEGHEA	SNX19	321	Q92543
EETPFPHEGPEVGRG	ZNF469	686	Q96JG9
GADSDGQPGPGEADH	VAX2	61	Q9UIW0
RPHPEDGDGQSLEGV	ZSCAN18	371	Q8TBC5
RGEGGSEDGSEDGLP	ZNF217	436	O75362
QGPEPAEDGGHLASE	MYO9B	1086	Q13459
EEHEGGGSRSPAGGE	NAA30	46	Q147X3