Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

2.52e-1426718GO:0005248
GeneOntologyMolecularFunctionsodium channel activity

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.13e-1152718GO:0005272
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

9.62e-1014715GO:0031402
GeneOntologyMolecularFunctionalkali metal ion binding

SCN1A SCN2A SCN3A SCN8A SCN9A

3.06e-0826715GO:0031420
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 ITPR2

3.34e-083437111GO:0005261
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ANO2 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 ITPR2

7.07e-084597112GO:0005216
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.65e-07171718GO:0015081
GeneOntologyMolecularFunctionchannel activity

ANO2 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 ITPR2

3.01e-075257112GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ANO2 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 ITPR2

3.07e-075267112GO:0022803
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 ITPR2

7.06e-074657111GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 ITPR2

1.95e-066277112GO:0022890
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ANO2 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 ITPR2

2.33e-067587113GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 ITPR2

3.52e-066647112GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ANO2 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 ITPR2

3.82e-067937113GO:0015075
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A SCN10A

2.83e-0517713GO:0099508
GeneOntologyMolecularFunctionunfolded protein binding

DNAJB11 CALR3 TOR1A HSPA2 HSPA6

8.62e-05126715GO:0051082
GeneOntologyMolecularFunctioncytoskeletal protein binding

MAPRE1 PTPN3 MYH6 SPIRE2 MYO6 SYNE1 SCN5A PXN TOR1A RDX DYSF HSPA2 FKBP4

1.17e-0410997113GO:0008092
GeneOntologyMolecularFunctionprotein folding chaperone

CALR3 TOR1A HSPA2 HSPA6

1.33e-0473714GO:0044183
GeneOntologyMolecularFunctiontransporter activity

ANO2 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A OSBPL5 SCN9A SCN10A COX7A2L TRPM1 ITPR2

1.52e-0412897114GO:0005215
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN5A SCN10A

1.85e-046712GO:0086006
GeneOntologyMolecularFunctiontransmembrane transporter activity

ANO2 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 ITPR2

2.36e-0411807113GO:0022857
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

TOR1A HSPA2 HSPA6

3.87e-0440713GO:0140662
GeneOntologyMolecularFunctioncalmodulin binding

MYH6 MYO6 SCN2A SCN3A SCN5A

1.36e-03230715GO:0005516
GeneOntologyMolecularFunctionmisfolded protein binding

DNAJB11 TOR1A

1.84e-0318712GO:0051787
GeneOntologyMolecularFunctionscaffold protein binding

SCN5A PLCG2 ITPR2

4.45e-0393713GO:0097110
GeneOntologyBiologicalProcessmembrane depolarization during action potential

PTPN3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.00e-1536729GO:0086010
GeneOntologyBiologicalProcessmembrane depolarization

PTPN3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TBX5

1.31e-111217210GO:0051899
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.30e-1162728GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.91e-1163728GO:0019228
GeneOntologyBiologicalProcessactin filament-based movement

MYH6 MYO6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.36e-101537210GO:0030048
GeneOntologyBiologicalProcessactin-mediated cell contraction

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

5.86e-10127729GO:0070252
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

6.93e-1087728GO:0086001
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.19e-0993728GO:0086003
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

5.26e-09112728GO:0019226
GeneOntologyBiologicalProcesscardiac muscle contraction

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

6.62e-09167729GO:0060048
GeneOntologyBiologicalProcessaction potential

PTPN3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

3.32e-08201729GO:0001508
GeneOntologyBiologicalProcesssodium ion transmembrane transport

PTPN3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.46e-08208729GO:0035725
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

ANO2 PTPN3 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 PLCG2 DYSF HSPA2 ITPR2

5.49e-0810177217GO:0098660
GeneOntologyBiologicalProcessstriated muscle contraction

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

6.41e-08217729GO:0006941
GeneOntologyBiologicalProcessheart contraction

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TBX5

8.29e-082987210GO:0060047
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

PTPN3 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 PLCG2 DYSF HSPA2 ITPR2

8.73e-089227216GO:0098662
GeneOntologyBiologicalProcessheart process

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TBX5

1.16e-073097210GO:0003015
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

PTPN3 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 PLCG2 DYSF HSPA2 ITPR2

1.17e-079427216GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ANO2 PTPN3 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 PLCG2 DYSF HSPA2 ITPR2

2.05e-0711157217GO:0034220
GeneOntologyBiologicalProcessmetal ion transport

PTPN3 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 PLCG2 DYSF HSPA2 FKBP4 ITPR2

2.63e-0710007216GO:0030001
GeneOntologyBiologicalProcessmonoatomic cation transport

PTPN3 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 PLCG2 DYSF HSPA2 FKBP4 ITPR2

3.46e-0711577217GO:0006812
GeneOntologyBiologicalProcesssodium ion transport

PTPN3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.77e-07275729GO:0006814
GeneOntologyBiologicalProcessmonoatomic ion transport

ANO2 PTPN3 TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L TRPM1 PLCG2 DYSF HSPA2 FKBP4 ITPR2

7.82e-0713747218GO:0006811
GeneOntologyBiologicalProcessregulation of membrane potential

PTPN3 SYNE1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TBX5

3.55e-065597211GO:0042391
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane depolarization

SCN5A SCN10A TBX5

4.81e-0610723GO:0060371
GeneOntologyBiologicalProcessmuscle contraction

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.03e-05400729GO:0006936
GeneOntologyBiologicalProcessactin filament-based process

MYH6 SPIRE2 MYO6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A PXN RDX

1.43e-059127213GO:0030029
GeneOntologyBiologicalProcessresponse to abiotic stimulus

MMP24 CALB1 HUS1 MYO6 SYNE1 SCN1A SCN2A SCN9A SCN10A TRPM1 RPGR DYSF HSPA2 HSPA6 GRK1 ITPR2

1.44e-0513617216GO:0009628
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception of pain

MMP24 SCN1A SCN9A SCN10A

1.52e-0543724GO:0062149
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte communication

SCN5A SCN10A TBX5

1.80e-0515723GO:0086069
GeneOntologyBiologicalProcessregulation of membrane depolarization

PTPN3 SCN5A SCN10A TBX5

6.13e-0561724GO:0003254
GeneOntologyBiologicalProcessblood circulation

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TBX5

8.10e-056487210GO:0008015
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception of pain

MMP24 SCN9A SCN10A

1.00e-0426723GO:0050965
GeneOntologyBiologicalProcessmuscle system process

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.17e-04547729GO:0003012
GeneOntologyBiologicalProcessdetection of temperature stimulus involved in sensory perception

MMP24 SCN9A SCN10A

1.55e-0430723GO:0050961
GeneOntologyBiologicalProcesschaperone-mediated protein folding

TOR1A HSPA2 HSPA6 FKBP4

1.77e-0480724GO:0061077
GeneOntologyBiologicalProcessbehavioral response to pain

SCN3A SCN9A SCN10A

1.88e-0432723GO:0048266
GeneOntologyBiologicalProcessdetection of temperature stimulus

MMP24 SCN9A SCN10A

2.06e-0433723GO:0016048
GeneOntologyBiologicalProcessprotein folding

DNAJB11 CALR3 TOR1A HSPA2 HSPA6 FKBP4

2.19e-04246726GO:0006457
GeneOntologyBiologicalProcesscirculatory system process

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TBX5

2.21e-047337210GO:0003013
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

SCN5A SCN10A TBX5

2.26e-0434723GO:0086019
GeneOntologyBiologicalProcesschaperone cofactor-dependent protein refolding

TOR1A HSPA2 HSPA6

2.46e-0435723GO:0051085
GeneOntologyBiologicalProcessbundle of His cell action potential

SCN5A SCN10A

2.50e-047722GO:0086043
GeneOntologyBiologicalProcessbundle of His cell to Purkinje myocyte signaling

SCN5A SCN10A

2.50e-047722GO:0086028
GeneOntologyBiologicalProcessretina morphogenesis in camera-type eye

CALB1 TRPM1 RPGR GRK1

2.78e-0490724GO:0060042
GeneOntologyBiologicalProcessprotein maturation

DNAJB11 CALR3 PITRM1 TOR1A PISD HSPA2 HSPA6 FKBP4 NLRC4

2.94e-04619729GO:0051604
GeneOntologyBiologicalProcesscellular response to abiotic stimulus

HUS1 MYO6 SCN2A TRPM1 RPGR DYSF GRK1

3.11e-04371727GO:0071214
GeneOntologyBiologicalProcesscellular response to environmental stimulus

HUS1 MYO6 SCN2A TRPM1 RPGR DYSF GRK1

3.11e-04371727GO:0104004
GeneOntologyBiologicalProcesssensory perception of temperature stimulus

MMP24 SCN9A SCN10A

3.15e-0438723GO:0050951
GeneOntologyBiologicalProcessdetection of external stimulus

MMP24 SCN1A SCN9A SCN10A GRK1

3.48e-04173725GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

MMP24 SCN1A SCN9A SCN10A GRK1

3.67e-04175725GO:0009582
GeneOntologyBiologicalProcess'de novo' post-translational protein folding

TOR1A HSPA2 HSPA6

3.95e-0441723GO:0051084
GeneOntologyBiologicalProcesssensory perception of pain

MMP24 SCN1A SCN9A SCN10A

5.00e-04105724GO:0019233
GeneOntologyBiologicalProcess'de novo' protein folding

TOR1A HSPA2 HSPA6

5.56e-0446723GO:0006458
GeneOntologyBiologicalProcessnegative regulation of microtubule polymerization or depolymerization

MAPRE1 DYSF FKBP4

7.53e-0451723GO:0031111
GeneOntologyBiologicalProcessresponse to pain

SCN3A SCN9A SCN10A

7.53e-0451723GO:0048265
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

SCN5A SCN10A

7.75e-0412722GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

SCN5A SCN10A

7.75e-0412722GO:0086016
GeneOntologyBiologicalProcessresponse to temperature stimulus

MMP24 SCN9A SCN10A HSPA2 HSPA6

8.04e-04208725GO:0009266
GeneOntologyBiologicalProcessdetection of mechanical stimulus involved in sensory perception

SCN1A SCN9A SCN10A

1.04e-0357723GO:0050974
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

SCN5A SCN10A TBX5

1.15e-0359723GO:0086065
GeneOntologyBiologicalProcessnegative regulation of microtubule polymerization

MAPRE1 FKBP4

1.23e-0315722GO:0031115
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

SCN5A SCN10A

1.23e-0315722GO:0086067
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

MYO6 SCN1A SCN8A SCN9A SCN10A

1.46e-03238725GO:0050954
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

2.48e-1617708GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.24e-1429708GO:0034706
GeneOntologyCellularComponentcation channel complex

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A HSPA2

8.82e-08235709GO:0034703
GeneOntologyCellularComponentmonoatomic ion channel complex

ANO2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A HSPA2

5.02e-073787010GO:0034702
GeneOntologyCellularComponentaxon

CALB1 MYO6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TOR1A TRPM1 FKBP4 ITPR2

1.23e-068917014GO:0030424
GeneOntologyCellularComponenttransmembrane transporter complex

ANO2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L HSPA2

1.23e-065237011GO:1902495
GeneOntologyCellularComponenttransporter complex

ANO2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L HSPA2

2.01e-065507011GO:1990351
GeneOntologyCellularComponentT-tubule

SCN1A SCN2A SCN5A RDX DYSF

6.77e-0679705GO:0030315
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

3.94e-0520703GO:0033268
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

1.23e-0429703GO:0043194
GeneOntologyCellularComponentZ disc

MYH6 SCN1A SCN5A SCN8A PGM1

1.53e-04151705GO:0030018
GeneOntologyCellularComponentsarcomere

MYH6 SYNE1 SCN1A SCN5A SCN8A PGM1

1.86e-04249706GO:0030017
GeneOntologyCellularComponentI band

MYH6 SCN1A SCN5A SCN8A PGM1

2.37e-04166705GO:0031674
GeneOntologyCellularComponentcell cortex

MAPRE1 SPIRE2 CALB1 MYO6 PXN RDX ITPR2

2.40e-04371707GO:0005938
GeneOntologyCellularComponentmyofibril

MYH6 SYNE1 SCN1A SCN5A SCN8A PGM1

3.06e-04273706GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

MYH6 SYNE1 SCN1A SCN5A SCN8A PGM1

4.22e-04290706GO:0043292
GeneOntologyCellularComponentsarcolemma

SCN1A SCN2A SCN5A RDX DYSF

4.41e-04190705GO:0042383
GeneOntologyCellularComponentplasma membrane protein complex

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A HSPA2

1.19e-03785709GO:0098797
GeneOntologyCellularComponentcell tip

RDX TRPM1

1.46e-0317702GO:0051286
GeneOntologyCellularComponentintercalated disc

SCN1A SCN2A SCN5A

1.54e-0368703GO:0014704
GeneOntologyCellularComponentsupramolecular fiber

MAPRE1 DNAH3 MYH6 MYO6 SYNE1 SCN1A SCN5A SCN8A DYSF FKBP4 PGM1

1.77e-0311797011GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

MAPRE1 DNAH3 MYH6 MYO6 SYNE1 SCN1A SCN5A SCN8A DYSF FKBP4 PGM1

1.87e-0311877011GO:0099081
GeneOntologyCellularComponentcell pole

RDX TRPM1

2.02e-0320702GO:0060187
GeneOntologyCellularComponentpresynaptic membrane

ANO2 SCN1A SCN2A SCN8A SCN10A

2.36e-03277705GO:0042734
GeneOntologyCellularComponentpresynapse

ANO2 CALB1 MYO6 SCN1A SCN2A SCN8A SCN10A TOR1A DYSF

2.71e-03886709GO:0098793
GeneOntologyCellularComponentmain axon

SCN1A SCN2A SCN8A

3.32e-0389703GO:0044304
GeneOntologyCellularComponentmembrane protein complex

ANO2 SYNE1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A COX7A2L HSPA2

3.84e-0314987012GO:0098796
GeneOntologyCellularComponentcell-cell contact zone

SCN1A SCN2A SCN5A

3.88e-0394703GO:0044291
HumanPhenoSudden death

MYH6 SYNE1 SCN1A SCN5A SCN8A SCN10A PGM1 TBX5

3.18e-06131378HP:0001699
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A SCN9A

4.03e-0616374HP:0011172
HumanPhenoLimitation of knee mobility

SCN1A SCN2A SCN9A TOR1A DYSF

4.24e-0635375HP:0010501
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A

1.93e-058373HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A

1.93e-058373HP:0200048
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A

2.67e-0525374HP:0006813
HumanPhenoAbnormal knee physiology

SYNE1 SCN1A SCN2A SCN9A TOR1A DYSF

3.17e-0587376HP:0034670
HumanPhenoLimited knee extension

SCN1A SCN2A SCN9A DYSF

3.67e-0527374HP:0003066
HumanPhenoSimple febrile seizure

SCN1A SCN2A SCN3A SCN8A

3.67e-0527374HP:0011171
HumanPhenoPes valgus

SCN1A SCN2A SCN4A SCN9A TOR1A

4.46e-0556375HP:0008081
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A

5.59e-0511373HP:0000466
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A

7.42e-0512373HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN2A SCN8A

7.42e-0512373HP:0032898
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A SCN9A

9.35e-0534374HP:0011169
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

9.60e-0513373HP:0007058
HumanPhenoFacial tics

SCN1A SCN2A SCN9A

1.51e-0415373HP:0011468
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A SCN9A

1.51e-0415373HP:0007207
HumanPhenoCyanosis

MYH6 SCN1A SCN2A SCN4A SCN8A SCN9A

1.68e-04117376HP:0000961
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A SCN9A

1.85e-0416373HP:0025101
HumanPhenoFocal clonic seizure

SCN1A SCN2A SCN8A SCN9A

2.17e-0442374HP:0002266
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A

2.24e-0417373HP:0032663
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A

2.24e-0417373HP:0011151
HumanPhenoFirst degree atrioventricular block

MYH6 SCN5A SCN10A TBX5

2.60e-0444374HP:0011705
HumanPhenoClonic seizure

SCN1A SCN2A SCN3A SCN8A SCN9A

2.63e-0481375HP:0020221
HumanPhenoVisually-induced seizure

SCN1A SCN2A SCN9A

2.67e-0418373HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

2.67e-0418373HP:0032860
HumanPhenoPace of progression

SCYL2 FREM2 DNAJB11 MYH6 SYNE1 SCN1A SCN4A SCN5A SCN8A SCN9A SCN10A TOR1A DYSF MOCS1 PGM1 TBX5

2.87e-049113716HP:0003679
HumanPhenoAbnormal autonomic nervous system physiology

SYNE1 SCN3A SCN5A SCN9A SCN10A TBX5

2.99e-04130376HP:0012332
HumanPhenoAbnormal atrioventricular conduction

MYH6 SYNE1 SCN5A SCN10A DYSF TBX5

3.11e-04131376HP:0005150
HumanPhenoAtrioventricular nodal disease

MYH6 SYNE1 SCN5A SCN10A DYSF TBX5

3.11e-04131376HP:0005142
HumanPhenoAbnormal cardiac exercise stress test

SCN5A SCN10A TBX5

3.16e-0419373HP:0500018
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

3.69e-0420373HP:0032671
HumanPhenoHeart block

MYH6 SYNE1 SCN5A SCN10A DYSF TBX5

3.81e-04136376HP:0012722
HumanPhenoMortality/Aging

SCYL2 FREM2 MYH6 SYNE1 SCN1A SCN4A SCN5A SCN8A SCN10A TOR1A PGM1 TBX5

4.04e-045633712HP:0040006
HumanPhenoAge of death

SCYL2 FREM2 MYH6 SYNE1 SCN1A SCN4A SCN5A SCN8A SCN10A TOR1A PGM1 TBX5

4.04e-045633712HP:0011420
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

4.29e-0421373HP:0004684
HumanPhenoCongenital stationary night blindness

MYO6 TRPM1 GRK1

4.29e-0421373HP:0007642
HumanPhenoReflex seizure

SCN1A SCN2A SCN9A

4.94e-0422373HP:0020207
HumanPhenoAtrioventricular block

MYH6 SYNE1 SCN5A SCN10A TBX5

5.00e-0493375HP:0001678
HumanPhenoHeart block

MYH6 SYNE1 SCN5A SCN10A TBX5

5.00e-0493375HP:0001668
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

5.06e-045372HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

5.06e-045372HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

5.06e-045372HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

5.06e-045372HP:0032823
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

5.06e-045372HP:0032906
HumanPhenoAllodynia

SCN9A SCN10A

5.06e-045372HP:0012533
HumanPhenoDecreased/absent ankle reflexes

SCN9A SCN10A TOR1A DYSF

5.35e-0453374HP:0200101
HumanPhenoTibial torsion

SCN1A SCN2A SCN9A

5.65e-0423373HP:0100694
HumanPhenoBradycardia

SCN4A SCN5A SCN9A SCN10A TBX5

6.36e-0498375HP:0001662
HumanPhenoRight bundle branch block

MYH6 SCN5A SCN10A DYSF

7.07e-0457374HP:0011712
HumanPhenoTorsade de pointes

SCN5A SCN10A TBX5

7.27e-0425373HP:0001664
HumanPhenoNormal interictal EEG

SCN2A SCN8A

7.56e-046372HP:0002372
HumanPhenoMalignant hyperthermia

SCN4A SCN5A PGM1

8.18e-0426373HP:0002047
HumanPhenoCompulsive behaviors

PITRM1 SCN1A SCN2A SCN8A SCN9A TOR1A

8.48e-04158376HP:0000722
HumanPhenoCardiac arrest

SYNE1 SCN5A SCN10A TOR1A PGM1 TBX5

8.77e-04159376HP:0001695
HumanPhenoStatus epilepticus without prominent motor symptoms

SCN1A SCN2A SCN9A

9.15e-0427373HP:0031475
HumanPhenoEMG abnormality

SCYL2 MYH6 GBF1 SYNE1 SCN4A SCN5A DYSF MEGF10

9.71e-04293378HP:0003457
HumanPhenoFocal aware seizure

SCN1A SCN2A SCN9A

1.02e-0328373HP:0002349
HumanPhenoElbow contracture

SCYL2 SYNE1 SCN4A TOR1A MEGF10

1.03e-03109375HP:0034391
HumanPhenoEyelid myoclonia seizure

SCN2A SCN8A

1.05e-037372HP:0032678
HumanPhenoAbnormality of cardiac conduction

MYH6 SYNE1 SCN4A SCN5A SCN9A SCN10A TOR1A DYSF PGM1 TBX5

1.06e-034523710HP:0001665
HumanPhenoGeneralized tonic seizure

SCN1A SCN2A SCN8A SCN9A

1.10e-0364374HP:0010818
HumanPhenoStatus epilepticus with prominent motor symptoms

SCN1A SCN2A SCN9A

1.13e-0329373HP:0032658
HumanPhenoProlonged QTc interval

SCN5A SCN10A TBX5

1.13e-0329373HP:0005184
HumanPhenoSick sinus syndrome

MYH6 SCN5A SCN10A

1.13e-0329373HP:0011704
HumanPhenoLimb myoclonus

SCN2A SCN8A TOR1A

1.13e-0329373HP:0045084
HumanPhenoCardiac conduction abnormality

MYH6 SYNE1 SCN5A SCN10A DYSF TBX5

1.13e-03167376HP:0031546
HumanPhenoSudden cardiac death

SYNE1 SCN5A SCN10A PGM1 TBX5

1.17e-03112375HP:0001645
HumanPhenoLimited elbow movement

SCYL2 SYNE1 SCN4A TOR1A DYSF TBX5

1.17e-03168376HP:0002996
HumanPhenoMultifocal epileptiform discharges

SCN1A SCN2A SCN8A SCN9A

1.23e-0366374HP:0010841
HumanPhenoDecreased fetal movement

SCYL2 SYNE1 SCN3A SCN4A SCN8A TOR1A MEGF10

1.25e-03234377HP:0001558
HumanPhenoProgressive gait ataxia

SCN1A SCN2A SCN9A

1.25e-0330373HP:0007240
HumanPhenoSinus bradycardia

SCN5A SCN10A TBX5

1.25e-0330373HP:0001688
HumanPhenoProgressive ataxia

SCN1A SCN2A SCN9A

1.25e-0330373HP:0001329
HumanPhenoAbnormal morphology of the musculature of the neck

TRPM3 SYNE1 SCN4A TOR1A DYSF MEGF10

1.28e-03171376HP:0011006
HumanPhenoChildhood onset

GBF1 PITRM1 TRPM3 SYNE1 SCN1A SCN2A SCN3A SCN5A SCN8A GCDH RPGR PLCG2 GPNMB COG3 MEGF10

1.38e-039383715HP:0011463
HumanPhenoVentricular tachycardia

MYH6 SCN5A SCN10A TBX5

1.45e-0369374HP:0004756
HumanPhenoCogwheel rigidity

SCN1A SCN2A SCN9A

1.51e-0332373HP:0002396
HumanPhenoAreflexia

SCYL2 GBF1 SYNE1 SCN9A SCN10A TOR1A DYSF MEGF10

1.52e-03314378HP:0001284
MousePhenoabnormal action potential

MYO6 SCN1A SCN2A SCN5A SCN8A SCN9A SCN10A

1.07e-06133577MP:0005402
MousePhenoabnormal sensory capabilities/reflexes/nociception

SCYL2 MMP24 DNAJB11 PITRM1 TRPM3 MYO6 SCN1A SCN4A LTN1 SCN8A SCN9A SCN10A TOR1A RDX GCDH COX7A2L TRPM1 DYSF

1.45e-0514865718MP:0002067
MousePhenoabnormal heart electrocardiography waveform feature

MYO6 SYNE1 SCN1A SCN5A SCN10A TOR1A COX7A2L FKBP4 TBX5

1.96e-05377579MP:0010508
MousePhenodecreased heart rate

MYO6 SYNE1 SCN1A SCN5A SCN10A TOR1A COX7A2L FKBP4

2.03e-05288578MP:0005333
MousePhenoprolonged PR interval

MYO6 SYNE1 SCN5A TBX5

2.48e-0542574MP:0003896
MousePhenoabnormal heartbeat

MYH6 MYO6 SYNE1 SCN1A SCN5A SCN10A TOR1A COX7A2L FKBP4 TBX5

3.03e-055015710MP:0004085
MousePhenoabnormal impulse conducting system conduction

MYO6 SYNE1 SCN1A SCN5A SCN10A TOR1A COX7A2L FKBP4 TBX5

3.13e-05400579MP:0003137
MousePhenoabnormal reflex

SCYL2 MMP24 DNAJB11 PITRM1 MYO6 SCN1A SCN4A LTN1 SCN8A SCN10A TOR1A RDX GCDH COX7A2L TRPM1 DYSF

3.94e-0512945716MP:0001961
MousePhenoabnormal RR interval

MYO6 SCN1A SCN10A TOR1A COX7A2L FKBP4

4.59e-05160576MP:0010504
MousePhenolimb grasping

SCYL2 PITRM1 SCN4A LTN1 SCN8A TOR1A TRPM1 DYSF

4.80e-05325578MP:0001513
MousePhenoabnormal nervous system electrophysiology

CALB1 MYO6 SCN1A SCN2A SCN5A SCN8A SCN9A SCN10A

5.23e-05329578MP:0002272
MousePhenoabnormal heart rate

MYO6 SYNE1 SCN1A SCN5A SCN10A TOR1A COX7A2L FKBP4 TBX5

7.17e-05445579MP:0001629
MousePhenoatrioventricular block

MYO6 SYNE1 SCN5A TBX5

9.57e-0559574MP:0010519
MousePhenoneurodegeneration

PITRM1 MYO6 LTN1 SCN8A TOR1A RDX GCDH RPGR GRK1

1.05e-04468579MP:0002229
MousePhenoventricular premature beat

SCN1A SCN5A TBX5

1.39e-0425573MP:0009732
MousePhenoabnormal PR interval

MYO6 SYNE1 SCN5A TBX5

1.40e-0465574MP:0003901
MousePhenoheart block

MYO6 SYNE1 SCN1A SCN5A TBX5

1.64e-04127575MP:0010559
MousePhenoabnormal motor coordination/balance

MMP24 CALB1 PITRM1 MYO6 SYNE1 SCN1A SCN4A LTN1 SCN8A SCN10A TOR1A GCDH

1.69e-048735712MP:0001516
MousePhenoapnea

JAK1 SCN1A SCN10A

1.75e-0427573MP:0001957
MousePhenoirregular heartbeat

MYH6 SCN1A SCN5A TBX5

1.97e-0471574MP:0001636
MousePhenointraventricular block

SYNE1 SCN1A SCN5A TBX5

2.31e-0474574MP:0010560
MousePhenobundle branch block

SYNE1 SCN1A SCN5A TBX5

2.31e-0474574MP:0010636
MousePhenodystrophic muscle

SYNE1 SCN8A DYSF

2.93e-0432573MP:0000752
MousePhenoparaparesis

SYNE1 LTN1 SCN8A

2.93e-0432573MP:0009434
MousePhenoventricular fibrillation

SCN1A SCN5A

3.39e-047572MP:0006110
MousePhenoabnormal atrioventricular node conduction

MYO6 SYNE1 SCN5A TBX5

3.59e-0483574MP:0006141
MousePhenoabnormal mechanical nociception

MMP24 SCN9A SCN10A

4.17e-0436573MP:0002734
MousePhenofused outer hair cell stereocilia

MYO6 RDX

4.50e-048572MP:0004528
MousePhenohindlimb paresis

SYNE1 LTN1 SCN8A

4.53e-0437573MP:0031204
MousePhenoprolonged PQ interval

SCN5A TBX5

7.20e-0410572MP:0011953
MousePhenoabnormal nociception after inflammation

MMP24 TRPM3 SCN9A

7.56e-0444573MP:0002736
MousePhenoabsent gastric milk in neonates

SCYL2 SYNE1 SCN2A TOR1A

7.84e-04102574MP:0009546
MousePhenoskin inflammation

JAK1 SCN9A PLCG2 CLEC10A

8.74e-04105574MP:0004947
MousePhenoneuron degeneration

PITRM1 MYO6 LTN1 SCN8A RDX RPGR GRK1

1.01e-03391577MP:0003224
MousePhenoprolonged P wave

SCN5A TBX5

1.05e-0312572MP:0004071
MousePhenofused inner hair cell stereocilia

MYO6 RDX

1.05e-0312572MP:0004533
MousePhenoabnormal enzyme/coenzyme activity

JAK1 MYH6 COX7A2L PISD DSEL MOCS1

1.07e-03287576MP:0005584
MousePhenoabnormal respiratory function

JAK1 SCN1A SCN2A SCN4A LTN1 SCN8A SCN10A

1.13e-03399577MP:0002327
MousePhenoimpaired ability to fire action potentials

SCN1A SCN10A

1.24e-0313572MP:0002578
MousePhenoabnormal muscle fiber morphology

MYH6 SYNE1 SCN4A SCN5A LTN1 SCN8A DYSF

1.25e-03406577MP:0004087
MousePhenoparesis

SYNE1 LTN1 SCN8A

1.30e-0353573MP:0000754
MousePhenoincreased circulating amylase level

SCN4A A2ML1 ZMYM4 RETREG3

1.39e-03119574MP:0008806
MousePhenoabnormal breathing pattern

JAK1 SCN1A SCN2A SCN4A SCN8A SCN10A

1.41e-03303576MP:0001951
MousePhenoabnormal muscle physiology

MYH6 CALB1 MYO6 SYNE1 SCN4A SCN5A LTN1 SCN8A TOR1A RPGR DYSF

1.43e-039545711MP:0002106
MousePhenofibrillation

SCN1A SCN5A

1.44e-0314572MP:0006109
MousePhenosinus bradycardia

SCN5A SCN10A

1.44e-0314572MP:0010637
MousePhenoprolonged QT interval

SYNE1 SCN1A SCN5A

1.45e-0355573MP:0003233
MousePhenoimpaired balance

MYO6 LTN1 SCN8A TOR1A

1.48e-03121574MP:0001525
DomainNa_channel_asu

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.30e-1810718IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.30e-1810718IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.30e-1810718PF06512
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

2.43e-156716PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A

2.43e-156716IPR024583
DomainIon_trans_dom

TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 ITPR2

5.04e-131147111IPR005821
DomainIon_trans

TRPM3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TRPM1 ITPR2

5.04e-131147111PF00520
DomainIQ_motif_EF-hand-BS

MYH6 MYO6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.47e-12907110IPR000048
DomainIQ

MYH6 MYO6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

2.05e-12937110PS50096
DomainIQ

MYH6 MYO6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A

2.06e-1181719SM00015
DomainChannel_four-helix_dom

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.14e-1157718IPR027359
Domain-

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.14e-11577181.20.120.350
DomainIQ

MYH6 MYO6 SCN1A SCN3A SCN4A SCN8A SCN9A SCN10A

2.55e-1071718PF00612
DomainTRPM_tetra

TRPM3 TRPM1

8.51e-054712IPR032415
DomainTRPM_tetra

TRPM3 TRPM1

8.51e-054712PF16519
DomainEF-hand-dom_pair

CALB1 SCN1A SCN3A SCN8A SCN9A PLCG2 TBC1D9

1.08e-04287717IPR011992
DomainFERM_central

JAK1 PTPN3 RDX

8.56e-0449713IPR019748
DomainFERM_domain

JAK1 PTPN3 RDX

8.56e-0449713IPR000299
DomainFERM_1

JAK1 PTPN3 RDX

9.08e-0450713PS00660
DomainFERM_2

JAK1 PTPN3 RDX

9.08e-0450713PS00661
DomainFERM_3

JAK1 PTPN3 RDX

9.08e-0450713PS50057
DomainBand_41_domain

JAK1 PTPN3 RDX

9.08e-0450713IPR019749
DomainB41

JAK1 PTPN3 RDX

9.08e-0450713SM00295
Domain-

HSPA2 HSPA6

9.18e-04127122.60.34.10
DomainHSP70_peptide-bd

HSPA2 HSPA6

9.18e-0412712IPR029047
Domain-

HSPA2 HSPA6

1.08e-03137121.20.1270.10
DomainHeat_shock_70_CS

HSPA2 HSPA6

1.08e-0313712IPR018181
DomainHSP70_C

HSPA2 HSPA6

1.08e-0313712IPR029048
DomainHSP70

HSPA2 HSPA6

1.65e-0316712PF00012
DomainHSP70_2

HSPA2 HSPA6

1.87e-0317712PS00329
DomainHSP70_3

HSPA2 HSPA6

1.87e-0317712PS01036
DomainHSP70_1

HSPA2 HSPA6

1.87e-0317712PS00297
DomainHsp_70_fam

HSPA2 HSPA6

2.10e-0318712IPR013126
DomainEz/rad/moesin-like

PTPN3 RDX

2.86e-0321712IPR000798
DomainFERM_CS

PTPN3 RDX

3.73e-0324712IPR019747
DomainFERM_C

PTPN3 RDX

4.37e-0326712PF09380
DomainFERM_C

PTPN3 RDX

4.70e-0327712SM01196
DomainFERM_PH-like_C

PTPN3 RDX

4.70e-0327712IPR018980
DomainPH_dom-like

JAK1 PTPN3 OSBPL5 RDX PLCG2 MTMR10

5.59e-03426716IPR011993
DomainFERM_N

PTPN3 RDX

6.97e-0333712PF09379
DomainFERM_N

PTPN3 RDX

6.97e-0333712IPR018979
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

4.21e-1331598M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

5.59e-1332598M27455
PathwayREACTOME_MUSCLE_CONTRACTION

MYH6 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A PXN DYSF ITPR2 TBX5

1.76e-122035913M5485
PathwayREACTOME_CARDIAC_CONDUCTION

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A ITPR2 TBX5

1.34e-101305910M27454
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A RDX

1.64e-09121599M872
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN3A SCN8A

5.26e-0628594M45519
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A PLCG2

1.98e-05367599M48346
PathwayWP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION

MMP24 SCN8A SCN9A SCN10A

3.96e-0546594M46450
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

PLXNC1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A RDX

1.22e-045755910M29853
PathwayREACTOME_ATTENUATION_PHASE

HSPA2 HSPA6 FKBP4

2.12e-0428593M27254
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA2 HSPA6 FKBP4

5.29e-0438593M27255
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

PLCG2 ITPR2

6.08e-049592M47852
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

2.03e-21972816382098
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A SCN8A SCN9A SCN10A

6.36e-17672623652591
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A

2.05e-161372715123669
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A

5.32e-15972615746173
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN3A SCN4A SCN5A SCN8A

3.30e-14572517724025
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A SCN8A

1.69e-11472417537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A SCN8A

1.69e-11472435031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A SCN8A

1.69e-11472429578003
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A SCN5A SCN8A

2.58e-111272530175250
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A SCN9A

8.43e-1157248812438
Pubmed

Early development of electrical excitability in the mouse enteric nervous system.

SCN3A SCN5A SCN8A SCN9A

8.43e-11572422875929
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN3A SCN9A

8.51e-09372319284629
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

8.51e-09372312610651
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN3A SCN9A

8.51e-09372333895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

8.51e-09372323859570
Pubmed

Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.

SCN3A SCN9A SCN10A

8.51e-09372319699781
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

8.51e-09372318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

8.51e-09372317544618
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

8.51e-09372332845893
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN5A SCN9A

8.51e-09372320038812
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

8.51e-09372328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

8.51e-09372317928448
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

8.51e-09372314973256
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

1.66e-0813972716985003
Pubmed

Several common variants modulate heart rate, PR interval and QRS duration.

MYH6 SCN5A SCN10A TBX5

1.66e-081472420062063
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

3.40e-08472321156207
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

SCN1A SCN9A SCN10A

3.40e-08472322260870
Pubmed

Genome-wide association studies of the PR interval in African Americans.

SCN5A SCN10A TBX5

3.40e-08472321347284
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

3.40e-08472335801810
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

3.40e-0847238974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

8.48e-0857231679748
Pubmed

Genetic variation in T-box binding element functionally affects SCN5A/SCN10A enhancer.

SCN5A SCN10A TBX5

8.48e-08572322706305
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

8.48e-08572324337656
Pubmed

Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.

SCN8A SCN9A SCN10A

1.69e-07672316029194
Pubmed

An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.

SCN3A SCN8A SCN10A

1.69e-07672323711479
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

2.96e-07772325818041
Pubmed

Novel loci associated with PR interval in a genome-wide association study of 10 African American cohorts.

SCN5A SCN10A TBX5

2.96e-07772323139255
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN5A SCN8A

2.96e-07772315272007
Pubmed

Pain without nociceptors? Nav1.7-independent pain mechanisms.

SCN3A SCN9A SCN10A

2.96e-07772324440715
Pubmed

Significant determinants of mouse pain behaviour.

SCN3A SCN9A SCN10A

4.73e-07872325101983
Pubmed

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.

SCN1A SCN4A SCN5A

4.73e-0787239412493
Pubmed

Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.

SCN3A SCN9A SCN10A

7.08e-0797238854872
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN5A SCN8A

7.08e-07972317884088
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

JAK1 MAPRE1 GBF1 PITRM1 LTN1 TOR1A PISD COG3 HSPA2 HSPA6 PGM1 RETREG3

1.74e-061061721233845483
Pubmed

Genome-wide association study of PR interval.

SCN5A SCN10A TBX5

1.85e-061272320062060
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

1.85e-06127238169823
Pubmed

Confirmation of quantitative trait loci for alcohol preference in mice.

SCN1A SCN2A SCN3A

3.80e-06157239726281
Pubmed

A common genetic variant within SCN10A modulates cardiac SCN5A expression.

SCN5A SCN10A

4.23e-06272224642470
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

4.23e-06272229649454
Pubmed

Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.

TRPM3 TRPM1

4.23e-06272221278253
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

4.23e-06272220346423
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

4.23e-06272237901435
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

4.23e-06272218079277
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

4.23e-06272226410685
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

4.23e-06272210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

4.23e-06272219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

4.23e-06272235348308
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

4.23e-06272211245985
Pubmed

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.

SCN5A SCN9A

4.23e-06272226861708
Pubmed

Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.

SCN5A SCN10A

4.23e-06272215047701
Pubmed

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

SCN9A SCN10A

4.23e-06272216111501
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

4.23e-06272215760941
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

4.23e-0627221317301
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

4.23e-06272223016767
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

4.23e-06272227153334
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

4.23e-06272233096315
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

4.23e-06272224990319
Pubmed

Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.

SCN4A SCN5A

4.23e-06272230944319
Pubmed

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

SCN3A SCN9A

4.23e-06272225172946
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

4.23e-06272231439038
Pubmed

Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.

SCN5A SCN10A

4.23e-06272231292628
Pubmed

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1.

PTPN3 SCN5A

4.23e-06272216930557
Pubmed

Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.

SCN1A SCN5A

4.23e-06272216054936
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

4.23e-06272217805013
Pubmed

Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.

SCN1A SCN5A

4.23e-06272233712547
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

4.23e-06272226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

4.23e-06272233411788
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

4.23e-06272231943325
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

4.23e-06272211834499
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

4.23e-06272215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

4.23e-06272227690330
Pubmed

TMEM16B determines cholecystokinin sensitivity of intestinal vagal afferents of nodose neurons.

ANO2 SCN10A

4.23e-06272230843875
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

4.23e-06272227174182
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

4.23e-06272221377452
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

4.23e-06272218601978
Pubmed

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

SCN5A SCN10A

4.23e-06272224998131
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

4.23e-06272223965409
Pubmed

Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI.

MYH6 MYO6

4.23e-06272218511944
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

4.23e-06272219465131
Pubmed

Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.

SCN2A SCN5A

4.23e-06272216847056
Pubmed

From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.

SCN5A SCN10A

4.23e-06272224360055
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

4.23e-06272237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

4.23e-06272217881658
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

4.23e-06272230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

4.23e-06272223735284
Pubmed

Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.

SCN5A SCN10A

4.23e-06272232330377
Pubmed

Identification of three novel genetic variations associated with electrocardiographic traits (QRS duration and PR interval) in East Asians.

SCN5A SCN10A TBX5

4.67e-061672325035420
Pubmed

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

SCN5A SCN10A TBX5

5.67e-061772321076409
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

1.27e-05372228784306
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

1.27e-05372232185219
InteractionSCN11A interactions

SCN1A SCN5A SCN8A SCN9A SCN10A

1.37e-0915715int:SCN11A
InteractionCACNA1D interactions

CALB1 SCN1A SCN5A SCN9A SCN10A

1.90e-0824715int:CACNA1D
InteractionSCN5A interactions

SCN1A SCN5A SCN8A SCN9A SCN10A

6.43e-0747715int:SCN5A
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

2.32e-068713int:SCN4B
InteractionSCN1A interactions

SCN1A SCN5A SCN9A SCN10A

3.14e-0629714int:SCN1A
InteractionSCN10A interactions

SCN1A SCN5A SCN10A

6.78e-0611713int:SCN10A
InteractionNALCN interactions

SCN1A SCN5A SCN9A

1.48e-0514713int:NALCN
InteractionSCN8A interactions

SCN4A SCN5A SCN8A

4.58e-0520713int:SCN8A
InteractionSCN9A interactions

SCN1A SCN5A SCN9A

5.32e-0521713int:SCN9A
CytobandEnsembl 112 genes in cytogenetic band chr2q24

SCN1A SCN2A SCN3A SCN9A

4.97e-05127724chr2q24
Cytoband2q24

SCN3A SCN9A

1.32e-04117222q24
Cytoband2q24.3

SCN1A SCN2A

2.87e-04167222q24.3
Cytoband15q13.3

TRPM1 MTMR10

7.69e-042672215q13.3
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

2.39e-2095281203
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

JAK1 PTPN3 RDX

4.00e-04505231293
GeneFamilyHeat shock 70kDa proteins

HSPA2 HSPA6

1.07e-0317522583
GeneFamilyTransient receptor potential cation channels

TRPM3 TRPM1

2.92e-0328522249
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

MMP24 PTPN3 CALB1 PLXNC1 SCN2A SCN3A SCN8A SCN9A ZNF25 TBC1D9

4.33e-065847210M39068
CoexpressionGSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP

HELZ2 PXN PLCG2 DYSF NLRC4 ITPR2

1.83e-05199726M5357
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A TBC1D9 TBX5

3.27e-071697260332f539a2f7d6dcd081a5d2f567290721f5a329
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A TBC1D9 TBX5

4.73e-07180726788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCellCOVID-19-kidney-CNT|COVID-19 / Disease (COVID-19 only), tissue and cell type

FREM2 PTPN3 CALB1 TRPM3 SCN2A SCN3A

6.90e-07192726760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 MYO6 SCN2A MTMR10 TBC1D9

8.51e-071997263cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN1A SCN2A TOR1A PLCG2

4.65e-06151725f41c6558a5874b6464c157027fdf202257c60e5b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 CALB1 MYO6 SCN2A TBC1D9

5.98e-0615972550d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 TRPM3 SCN2A PLCG2 MTMR10

8.28e-06170725928e42c51a7079c506f21c669c4e4c1a0df84d77
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A HSPA2 TBC1D9

9.53e-06175725787ac1a12cda10af5c8830471702a4cbaf43e79e
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MYO6 SYNE1 OSBPL5 DSEL HSPA6

1.18e-05183725983ca1342ddd365e1f1df32a456394b002b10e41
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 FREM2 TRPM3 SCN2A SCN9A

1.21e-051847252cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 FREM2 TRPM3 SCN2A SCN9A

1.21e-05184725ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANO2 FREM2 TRPM3 SCN2A SCN9A

1.21e-051847252b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A TBC1D9

1.28e-0518672508632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A MTMR10 TBC1D9

1.28e-05186725b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A MTMR10

1.31e-05187725f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SPIRE2 SCN2A SCN3A SCN9A TBC1D9

1.35e-05188725b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A MTMR10 TBC1D9

1.38e-051897258ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 MYO6 SCN2A SCN3A PLCG2

1.38e-05189725532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTPN3 CALB1 MYO6 A2ML1 TMPRSS11B

1.45e-05191725fbd8d337b4444fba8527a614e4a8bfb516ce0f66
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A MTMR10 TBC1D9

1.49e-051927250bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCellCOPD-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

JAK1 SYNE1 OSBPL5 PXN PLCG2

1.53e-051937250020249fa71afb500af73700543bb6f349be6b10
ToppCellNS-critical-d_0-4-Epithelial-Squamous|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN3 CALB1 MYO6 A2ML1 TMPRSS11B

1.57e-05194725614d0c25b56957c70f397abb169fd2a860eb1c06
ToppCellCOVID-19-kidney-Glomerular_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

SYNE1 PXN RPGR PLCG2 DYSF

1.57e-05194725660535b492445063d965095a50e1e299ce04c50a
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SYNE1 SCN9A CLEC10A HSPA6 ITPR2

1.57e-0519472558046894446cb250814252a23f60fdd59c114d77
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

ANO2 PXN RPGR PLCG2 DYSF

1.61e-05195725a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CALB1 TRPM3 TRPM1 DSEL TBX5

1.61e-051957252fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

CALB1 TRPM3 TRPM1 DSEL TBX5

1.61e-0519572506a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCellNS-critical-d_16-33-Epithelial-Squamous|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN3 CALB1 MYO6 A2ML1 TMPRSS11B

1.65e-0519672597e16d9833e4083d719ca7058d5fc9b11edb37e3
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SCN1A SCN2A SCN3A SCN8A

1.73e-05198725c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SCN1A SCN2A SCN3A SCN8A

1.73e-051987256d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYNE1 SCN1A SCN2A SCN3A SCN8A

1.73e-051987254ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 MYO6 SCN2A MTMR10 TBC1D9

1.77e-05199725a4ebb0598e9a0c9f6e39a0db6d0623654c2a7d88
ToppCellhuman_hepatoblastoma-Tumor_cells-T9|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SCYL2 MAPRE1 PLCG2 HSPA6 FKBP4

1.77e-05199725e9c83555d2197b740797a9f33b64f8f7a7ba1ee2
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A GPNMB

1.81e-05200725f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A GPNMB

1.81e-05200725cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A GPNMB

1.81e-05200725c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A GPNMB

1.81e-052007254fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A GPNMB

1.81e-05200725310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SCN1A SCN2A SCN3A SCN9A GPNMB

1.81e-05200725961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-Unfolded_protein_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

WDR64 OSBPL5 TOR1A PISD

2.75e-051077247fee0193ee02e9cc62f506660ea7ec23fb4d0c84
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANO2 TRPM3 SCN2A PLCG2

6.06e-05131724d706405453408fbcfcabb1c7702b80f9e649ffca
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A TRPM1

6.81e-051357247b456fa9a5f5ce58976a8f1fad18c0f96a096930
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A PLCG2 TBC1D9

7.21e-0513772481cdb216e6c81acf9c2072f9d39e1a42612e1258
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 SCN1A SCN9A SCN10A

8.98e-0514572496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A

9.47e-051477242885978bcfc5623967c0c1204dadf5c78c74a082
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALB1 PLXNC1 GRK1 TBX5

9.72e-05148724dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A

1.08e-04152724eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 MYO6 SCN2A TBC1D9

1.11e-041537249b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PTPN3 MYO6 SCN2A TBC1D9

1.11e-0415372479c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 MYO6 SCN2A TBC1D9

1.22e-041577242c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 SCN9A SCN10A GPNMB

1.25e-04158724f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FREM2 SCN9A SCN10A GPNMB

1.25e-041587248c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 SCN10A DEPDC1 TRPM1

1.31e-0416072441d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A PLCG2 TBC1D9

1.31e-0416072486fde32f096eaf9ea3677f57169cdcc0a57bb8dd
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH6 SCN10A DEPDC1 TRPM1

1.31e-04160724c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FREM2 SCN9A SCN10A MEGF10

1.38e-04162724bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A

1.38e-04162724285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 OSBPL5 PGM1 ITPR2

1.44e-04164724950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCelldroplet-Liver-nan-3m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 OSBPL5 PGM1 ITPR2

1.44e-04164724c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCelldroplet-Liver-nan-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCYL2 OSBPL5 PGM1 ITPR2

1.44e-04164724bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A

1.44e-041647246fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRPM3 SCN1A SCN5A MEGF10

1.55e-0416772449b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCellControl|World / group, cell type (main and fine annotations)

FREM2 MYO6 SYNE1 SCN1A

1.58e-04168724a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO6 SYNE1 ZNF25 TBX5

1.66e-04170724f0b0d2d0402de3ed7322284a599646db43475761
ToppCell368C-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO6 SYNE1 ZNF25 TBX5

1.66e-04170724054360a3b05f5e41221c98b122d241b1affad26a
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PLCG2 DSEL HSPA2 HSPA6

1.77e-041737245d3c917e4d0de3158550a8ab2006ddfa87159ffa
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MMP24 SCN9A PLCG2 ITPR2

1.85e-04175724a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SCN1A SCN5A SCN8A MEGF10

1.93e-041777245357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A TBC1D9

1.93e-04177724dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A PLCG2

1.93e-04177724f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PLXNC1 SYNE1 DYSF NLRC4

2.02e-04179724cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PXN RPGR PLCG2 HSPA6

2.02e-04179724754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A TBC1D9

2.02e-04179724666072c0e8448dbaec1683d18368ec2502453f90
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FREM2 SCN2A SCN3A TBC1D9

2.02e-04179724d3438fed0d85d5ed5afa8ff820c45143d77b6c0d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP24 SCN1A CLEC10A TBC1D9

2.06e-04180724d76349ecef7c5878bf215e946f032264161eb61b
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM3 SCN9A MEGF10 PGM1

2.06e-0418072438490017dd590e3fcfa7e88d8d15235d55f90cf1
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM3 DEPDC1 GPNMB TBC1D9

2.06e-0418072443fd5c498a87bb078d101298b472656f3294686a
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANO2 TRPM3 SCN9A MEGF10

2.11e-04181724098dbb3e0ff531c9720a233123250c1e39a97d4c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FREM2 TRPM3 SCN2A TBC1D9

2.11e-04181724aa233b652921848af2257cc3687a7a09c3acfb67
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CALB1 SCN2A SCN5A SCN9A

2.11e-041817247f99002a6411117cc2361334c7c9228e20c574b4
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRPM3 SCN1A SCN9A MEGF10

2.11e-04181724fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TRPM3 SCN1A SCN9A MEGF10

2.15e-04182724b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A TBC1D9

2.15e-041827245f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRPM3 SCN1A SCN9A MEGF10

2.15e-04182724ecb5624c9074cc6449fad961df54c926c2681d54
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A TBC1D9

2.20e-04183724b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 TRPM3 SCN2A SCN3A

2.20e-04183724d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM3 DEPDC1 GPNMB TBC1D9

2.20e-04183724e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A TBC1D9

2.20e-041837242e831a4d99c6f983793df71c0994124c943c6da9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A TBC1D9

2.24e-041847249690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A MTMR10 TBC1D9

2.29e-04185724d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCellPCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP1_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TRPM3 SCN1A SCN9A MEGF10

2.29e-04185724a8946379fc066903fe8f4bc9cbf693b7b424a0cd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CALB1 SCN2A SCN3A TBC1D9

2.34e-04186724d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MMP24 SPIRE2 SCN9A TBC1D9

2.34e-041867249d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellPCW_07-8.5-Neuronal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRPM3 SCN1A SCN9A MEGF10

2.34e-041867247a4bb42f3f6a27b463e48eafc587d9ab3386f2fb
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCN1A SCN2A SCN8A TBC1D9

2.38e-041877247b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A PLCG2

2.38e-041877242d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 SCN2A SCN3A MTMR10

2.38e-04187724e3095455d2f255854f339f6b05fa87852af0700f
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYH6 SCN5A DYSF TBX5

2.43e-041887246d249fe92d51a19da19ec14bb2262d394255d577
ToppCellCOPD-Lymphoid-NK|COPD / Disease state, Lineage and Cell class

SYNE1 OSBPL5 PXN PLCG2

2.43e-04188724c9a227c8e71b69929d43e9afb8306a95c8163778
ToppCellCOVID-19-kidney-DCT|kidney / Disease (COVID-19 only), tissue and cell type

PTPN3 SCN2A SCN3A TBC1D9

2.43e-04188724df1fd0819d301679f3c9ea404e942e39095912eb
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN3A SCN4A SCN8A SCN10A

1.64e-126725ctd:C475726
DrugZonisamide

SCN1A SCN2A SCN3A SCN4A SCN5A SCN9A

9.73e-1217726DB00909
Drug2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate

SCN2A SCN3A SCN8A SCN10A

6.37e-098724ctd:C489827
DrugAC1L1MOZ

SCN3A SCN4A SCN5A SCN9A SCN10A

2.10e-0827725CID000031958
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN3A SCN4A SCN9A

3.03e-083723ctd:C561228
Drugtocainide

SCN3A SCN4A SCN5A SCN9A SCN10A

3.68e-0830725CID000038945
Drugamiodarone

MYH6 SCN3A SCN4A SCN5A SCN9A SCN10A PLCG2 TBC1D9

4.08e-08160728CID000002156
Drugsaxitoxin

MYH6 SCN2A SCN3A SCN4A SCN9A SCN10A

5.76e-0865726CID000037165
Drugbenzocaine

SCN2A SCN3A SCN4A SCN9A SCN10A

1.11e-0737725CID000002337
DrugLidocaine

SCN5A SCN9A SCN10A

1.21e-074723DB00281
DrugAPETx2 protein, Anthopleura elegantissima

SCN2A SCN8A SCN10A

1.21e-074723ctd:C501880
DrugTetrodotoxin

SCN2A SCN3A SCN5A SCN8A SCN9A

1.66e-0740725ctd:D013779
DrugSodium

SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A

2.71e-0784726ctd:D012964
DrugScorpion Venoms

SCN2A SCN3A SCN4A SCN9A

2.72e-0718724ctd:D012604
Drugpilsicainide

SCN3A SCN4A SCN5A SCN9A SCN10A

3.40e-0746725CID000004820
Drugdiprafenone

SCN3A SCN4A SCN9A SCN10A

3.44e-0719724CID000071249
Drugfenpropathrin

SCN2A SCN3A SCN10A

6.02e-076723ctd:C044267
DrugAC1NT1AF

SCN3A SCN4A SCN9A SCN10A

1.11e-0625724CID005322157
DrugPirmenolum

SCN3A SCN4A SCN9A SCN10A

1.30e-0626724CID000004853
DrugPbTx-1

SCN3A SCN4A SCN9A SCN10A

1.53e-0627724CID006437089
Drugnefopam

SCN3A SCN4A SCN9A SCN10A

1.53e-0627724CID000004450
Drugparaben

SCN3A SCN4A SCN9A SCN10A

1.78e-0628724CID000007175
Druglamotrigine

SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A

1.82e-06116726CID000003878
DrugAC1L1CQC

SCN3A SCN4A SCN5A SCN9A SCN10A

1.96e-0665725CID000002012
Drugmexiletine

SCN3A SCN4A SCN5A SCN9A SCN10A

2.11e-0666725CID000004178
Drugdisopyramide

SCN3A SCN4A SCN5A SCN9A SCN10A

2.11e-0666725CID000003114
Drugdibucaine

SCN3A SCN4A SCN5A SCN9A SCN10A

2.45e-0668725CID000003025
DrugMexiletine

SCN5A SCN9A SCN10A

2.51e-069723ctd:D008801
Drugflecainide

SCN3A SCN4A SCN5A SCN9A SCN10A

3.04e-0671725CID000003355
DrugNSC93767

SCN3A SCN4A SCN9A SCN10A

3.09e-0632724CID000005658
Drugimide

SYNE1 SCN3A SCN4A SCN9A SCN10A

3.73e-0674725CID000443040
Drug5-hydroxypropafenone

SCN3A SCN4A SCN9A SCN10A

3.97e-0634724CID000107927
DrugNSC15627

SCN4A SCN5A SCN9A GPNMB

3.97e-0634724CID000002073
Drugclenbuterol

MYH6 MYO6 SCN3A SCN4A SCN9A SCN10A

5.90e-06142726CID000002783
Drugaprindine

SCN3A SCN4A SCN9A SCN10A

6.25e-0638724CID000002218
DrugS-ropivacaine

SCN3A SCN4A SCN9A SCN10A

7.71e-0640724CID000071273
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

9.86e-062722ctd:C502265
DrugHexylcaine

SCN5A SCN10A

9.86e-062722DB00473
DrugRanolazine

SCN5A SCN9A

9.86e-062722DB00243
DrugPhenytoin

SCN1A SCN5A

9.86e-062722DB00252
DrugFlecainide

SCN4A SCN5A

9.86e-062722DB01195
Drugspiradoline

SCN3A SCN4A SCN9A SCN10A

1.36e-0546724CID000005620
Drugpropafenone

SCN3A SCN4A SCN5A SCN9A SCN10A

1.48e-0598725CID000004932
Drugindoxacarb

SCN3A SCN4A SCN9A SCN10A

1.75e-0549724CID000107720
DrugPD 150606

SCN2A SCN3A PXN

2.00e-0517723ctd:C100442
Drugcarbamazepine

SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A

2.21e-05179726CID000002554
Drugmoricizine

SCN4A SCN5A SCN9A

2.39e-0518723CID000034632
DrugNSC7524

SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A

2.42e-05182726CID000005657
DrugAC1NSN3X

SCN3A SCN4A SCN9A SCN10A

2.58e-0554724CID005366189
DrugAC1NRC8M

PTPN3 SCN2A SCN3A

2.83e-0519723CID005288877
DrugDibucaine

SCN5A SCN10A

2.95e-053722DB00527
Drugtriamterene

SCN3A SCN4A SCN9A SCN10A

3.43e-0558724CID000005546
DrugMerbromin [129-16-8]; Up 200; 5uM; MCF7; HT_HG-U133A

SCN10A TRPM1 RPGR DYSF MOCS1 TBX5

3.67e-051967264722_UP
Drugdiaminopropionic acid

SYNE1 RDX GCDH FKBP4

4.19e-0561724CID000000364
Drugzonisamide

SCN3A SCN4A SCN9A SCN10A

4.46e-0562724CID000005734
Drugbepridil

SCN3A SCN4A SCN5A SCN9A SCN10A

4.98e-05126725CID000002351
Drugm-phenylenediamine

SYNE1 RDX FKBP4

5.13e-0523723CID000007935
Drugresiniferatoxin

SCN3A SCN4A SCN9A SCN10A

5.71e-0566724CID000104826
DrugFospropofol

SCN2A SCN4A

5.89e-054722DB06716
DrugPropofol

SCN2A SCN4A

5.89e-054722DB00818
Drugtetradotoxin

CALB1 SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

6.11e-05428728CID000020382
DrugMulticide

SCN2A SCN4A SCN9A

6.63e-0525723CID000024365
DrugGBR 12909

SCN3A SCN4A SCN9A SCN10A

6.80e-0569724CID000003455
Drugphenytoin

SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A

6.81e-05219726CID000001775
DrugT2755

SCN3A SCN4A SCN9A SCN10A

7.61e-0571724CID000005514
Druga-factor

SCN5A CLEC10A FKBP4 TBC1D9

8.48e-0573724CID000119102
Drug1, 3-diallylurea

SCN3A SCN4A SCN9A SCN10A

8.95e-0574724CID000074537
Drugencainide

SCN4A SCN5A SCN9A

9.39e-0528723CID000048040
DrugDPI 201-106

SCN4A SCN5A SCN9A

9.39e-0528723CID000005190
Drugisofagomine

SCN4A SCN5A SCN9A SCN10A

9.43e-0575724CID000447607
Drugdiphenhydramine

SCN3A SCN4A SCN9A SCN10A

9.43e-0575724CID000003100
DrugGlamin

RDX FKBP4

9.80e-055722CID000008390
Drugferrocenium hexafluorophosphate

SYNE1 GCDH

9.80e-055722CID011727263
Drugmethyl propionate

CALB1 FKBP4

9.80e-055722CID000011124
Drugdecamethrin

SCN1A SCN2A SCN3A SCN8A SCN10A

1.00e-04146725ctd:C017180
DrugAC1O581Q

DNAJB11 HSPA2 HSPA6

1.04e-0429723CID006453768
Drugcyfluthrin

SCN2A SCN3A SCN10A

1.04e-0429723ctd:C052570
Drugmethyl phenyl sulfone

SCN2A RDX FKBP4

1.04e-0429723CID000018369
Drugoxcarbazepine

SCN4A SCN5A SCN9A

1.16e-0430723CID000034312
Drugbupropion

SCN3A SCN4A SCN9A SCN10A

1.27e-0481724CID000000444
DrugQX-314

SCN4A SCN5A SCN9A PLCG2

1.33e-0482724CID000003925
Drug3,4-DNT

RDX GCDH

1.47e-046722CID000011883
Drugdihydrochloride

TRPM3 SCN3A SCN4A SCN9A SCN10A

1.50e-04159725CID000070978
Druglidocaine

SCN3A SCN4A SCN5A SCN9A SCN10A

1.54e-04160725CID000003676
Drugverapamil

MYH6 MYO6 SCN3A SCN4A SCN5A SCN9A SCN10A TBC1D9

1.56e-04490728CID000002520
DrugDB08666

SCN2A SCN4A SCN5A SF3A3

1.91e-0490724CID011840988
Druggabapentin

SCN3A SCN4A SCN5A SCN9A SCN10A

1.99e-04169725CID000003446
Drug2,6-DNT

RDX GCDH FKBP4

2.01e-0436723CID000011813
Drugcarbocyanine

ANO2 CALB1 DYSF

2.01e-0436723CID000017704
Drugfluorocyclobutane

SCN2A SCN4A

2.05e-047722CID011051569
Drugsipatrigine

SCN2A SCN4A SCN9A

2.18e-0437723CID000060803
Drugriluzole

SCN3A SCN4A SCN5A SCN9A SCN10A

2.28e-04174725CID000005070
Drugfenfluramine

SCN3A SCN4A SCN9A SCN10A DSEL

2.53e-04178725CID000003337
Drugranolazine

SCN4A SCN5A SCN9A

2.55e-0439723CID000056959
Drugvanillyl alcohol

CALB1 GRK1

2.73e-048722CID000062348
DrugCocaine

SCN5A SCN10A

2.73e-048722DB00907
Drugstrychnine HCl

SCN3A SCN4A SCN9A SCN10A MOCS1

2.73e-04181725CID000005304
Drugtrimethoprim

SCN3A SCN4A SCN9A SCN10A

2.76e-0499724CID000005578
Drugisradipine

SCN3A SCN4A SCN9A SCN10A

2.87e-04100724CID000003784
DrugThiostrepton [1393-48-2]; Up 200; 2.4uM; HL60; HT_HG-U133A

HUS1 SCN10A HSPA2 FKBP4 ITPR2

2.95e-041847252462_UP
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

3.35e-2010718DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

3.35e-2010718DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

3.67e-1912718DOID:0060170 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A

5.78e-09163718DOID:1826 (implicated_via_orthology)
DiseaseP wave duration

MYH6 SCN5A SCN10A TBX5

4.12e-0815714EFO_0005094
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A SCN9A

2.18e-0722714DOID:2030 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

1.11e-069713C3502809
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

3.75e-0613713C0751122
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

5.71e-062712C4551549
DiseaseBrugada syndrome

SCN5A SCN10A TBX5

1.26e-0519713MONDO_0015263
DiseaseB Virus Infection

SCN8A SCN9A

1.71e-053712C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

1.71e-053712cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

1.71e-053712C0032768
DiseaseSick sinus syndrome

MYH6 SCN5A

1.71e-053712cv:C0037052
DiseaseHerpesviridae Infections

SCN8A SCN9A

1.71e-053712C0019372
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN9A SCN10A

1.71e-053712C1833661
DiseasePrimary Erythermalgia

SCN9A SCN10A

1.71e-053712C0014805
DiseaseFamilial sick sinus syndrome

MYH6 SCN5A

1.71e-053712cv:C0340491
DiseaseChronic Infantile Neurological, Cutaneous, and Articular Syndrome

PLCG2 NLRC4

3.41e-054712C0409818
DiseaseFamilial Cold Autoinflammatory Syndrome 1

PLCG2 NLRC4

3.41e-054712C4551895
DiseaseBrugada ECG Pattern

SCN5A SCN10A

3.41e-054712C1721096
DiseaseCryopyrin-Associated Periodic Syndromes

PLCG2 NLRC4

3.41e-054712C2316212
DiseaseFamilial cold urticaria

PLCG2 NLRC4

3.41e-054712C0343068
DiseaseFamilial cold autoinflammatory syndrome

PLCG2 NLRC4

3.41e-054712cv:C0343068
DiseaseQRS complex

SCN10A TBX5

3.41e-054712EFO_0005054
Diseasesick sinus syndrome (is_implicated_in)

MYH6 SCN5A

5.68e-055712DOID:13884 (is_implicated_in)
DiseaseMuckle-Wells Syndrome

PLCG2 NLRC4

5.68e-055712C0268390
DiseaseCerebellar Ataxia

SYNE1 SCN8A

5.68e-055712C0007758
Diseaseheart function measurement

SCN5A SCN10A TBX5

7.57e-0534713EFO_0004311
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

8.51e-056712C0220669
DiseaseSick Sinus Syndrome

MYH6 SCN5A

8.51e-056712C0037052
DiseaseIntellectual Disability

PITRM1 TRPM3 SYNE1 SCN1A SCN3A SCN8A PISD

1.01e-04447717C3714756
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN9A SCN10A

1.19e-047712C0020075
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.19e-047712C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.19e-047712C0751057
Diseaseelectrocardiography, PR interval

SCN5A SCN10A

1.19e-047712EFO_0004327, EFO_0004462
DiseaseCongenital Pain Insensitivity

SCN9A SCN10A

1.19e-047712C0002768
DiseaseMASA syndrome (implicated_via_orthology)

TRPM3 TRPM1

1.19e-047712DOID:0060246 (implicated_via_orthology)
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A

1.41e-04109714C0014544
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

1.58e-048712C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

1.58e-048712C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

1.58e-048712C0338479
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

1.58e-048712C0438414
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

1.58e-048712C0751120
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

1.58e-048712C0393703
DiseaseQRS complex, QRS duration

SCN5A SCN10A TBX5

1.76e-0445713EFO_0005054, EFO_0005055
DiseaseFebrile Convulsions

SCN1A SCN2A

2.03e-049712C0009952
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

2.03e-049712C0014550
Diseasesupraventricular ectopy

SCN5A SCN10A

2.03e-049712EFO_0009277
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

2.54e-0410712C0917800
Diseaseelectrocardiography

PTPN3 MYH6 TRPM3 SCN5A SCN10A GPNMB TBX5

2.86e-04530717EFO_0004327
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

3.10e-0411712C0393702
Diseasedistal myopathy (implicated_via_orthology)

MYH6 DYSF

3.71e-0412712DOID:11720 (implicated_via_orthology)
DiseaseBrugada Syndrome 1

SCN5A SCN10A

4.38e-0413712C4551804
DiseaseT wave morphology measurement

SCN5A SCN10A

5.10e-0414712EFO_0008398
DiseaseParoxysmal atrial fibrillation

MYH6 SCN5A SCN10A TBX5

5.55e-04156714C0235480
Diseasefamilial atrial fibrillation

MYH6 SCN5A SCN10A TBX5

5.55e-04156714C3468561
DiseasePersistent atrial fibrillation

MYH6 SCN5A SCN10A TBX5

5.55e-04156714C2585653
DiseaseMMR-related febrile seizures

SCN1A SCN2A

5.87e-0415712EFO_0006519
DiseaseSinus Node Dysfunction (disorder)

MYH6 SCN10A

5.87e-0415712C0428908
DiseaseAtrial Fibrillation

MYH6 SCN5A SCN10A TBX5

6.10e-04160714C0004238
DiseaseNeuralgia, Supraorbital

SCN9A SCN10A

6.70e-0416712C0038870
DiseaseNeuralgia, Iliohypogastric Nerve

SCN9A SCN10A

6.70e-0416712C0423712
DiseaseNeuralgia, Perineal

SCN9A SCN10A

6.70e-0416712C0423711
DiseaseNeuralgia

SCN9A SCN10A

6.70e-0416712C0027796
DiseaseRomano-Ward Syndrome

SCN5A SCN10A

6.70e-0416712C0035828
DiseaseNeuralgia, Atypical

SCN9A SCN10A

6.70e-0416712C0234247
DiseaseNeuralgia, Stump

SCN9A SCN10A

6.70e-0416712C0234249
DiseaseParoxysmal Nerve Pain

SCN9A SCN10A

6.70e-0416712C0751373
DiseaseNerve Pain

SCN9A SCN10A

6.70e-0416712C0751372
DiseaseNeuralgia, Ilioinguinal

SCN9A SCN10A

6.70e-0416712C0751371
DiseaseNeuralgia, Vidian

SCN9A SCN10A

6.70e-0416712C0042656
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

6.70e-0416712C0393706
Diseaseurate measurement, bone density

SCYL2 WDR64 PLXNC1 SYNE1 A2ML1 HELZ2 ITPR2

7.20e-04619717EFO_0003923, EFO_0004531
DiseaseNight blindness, congenital stationary

TRPM1 GRK1

7.58e-0417712C0339535
Diseasemuscular dystrophy (is_implicated_in)

SYNE1 DYSF

7.58e-0417712DOID:9884 (is_implicated_in)
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

8.52e-0418712HP_0002373
DiseaseMyocardial Ischemia

MAPRE1 CLEC10A HSPA2 PGM1

8.71e-04176714C0151744
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A

1.03e-0382713C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A

1.03e-0382713C0751111
DiseaseAura

SCN1A SCN2A SCN8A

1.03e-0382713C0236018
DiseasePR interval

FREM2 TRPM3 SCN5A SCN10A DYSF TBX5

1.23e-03495716EFO_0004462
DiseaseNeurodevelopmental Disorders

SCN1A SCN2A SCN8A

1.48e-0393713C1535926
DiseaseBrugada Syndrome (disorder)

SCN5A SCN10A

1.52e-0324712C1142166
DiseaseAtaxia

PITRM1 SCN8A

1.65e-0325712C0004134
DiseaseLimb-girdle muscular dystrophy

MYH6 DYSF

1.79e-0326712cv:C0686353
DiseaseQT interval

GBF1 SCN5A SCN10A PXN ITPR2 TBX5

1.81e-03534716EFO_0004682
Diseaseatrial fibrillation

MYH6 SCN5A SCN10A ITPR2 TBX5

2.02e-03371715EFO_0000275
Diseasecongestive heart failure (biomarker_via_orthology)

MYH6 SCN5A SCN8A

2.22e-03107713DOID:6000 (biomarker_via_orthology)
Diseasecardiovascular age measurement

SCN5A SCN10A

2.22e-0329712EFO_0803380
Diseasenicotine use, generational effect measurement, illegal drug consumption, non-substance related disinhibited behaviour, alcohol drinking, alcohol dependence

WDR64 PLXNC1

2.22e-0329712EFO_0004329, EFO_0005430, EFO_0005431, EFO_0005432, EFO_0008364, MONDO_0007079
DiseasePrimary familial dilated cardiomyopathy

MYH6 SCN5A

2.38e-0330712cv:C0340427
DiseaseHuntington disease, disease progression measurement

TRPM1 MTMR10

2.38e-0330712EFO_0008336, MONDO_0007739
Diseaseestradiol measurement

JAK1 PLXNC1 FKBP4

2.40e-03110713EFO_0004697

Protein segments in the cluster

PeptideGeneStartEntry
KVFPADIDQKNLNGK

CALR3

111

Q96L12
NQEKDPLLKNQEFKG

GPNMB

556

Q14956
GQAQKFIFIDPKNIQ

A2ML1

1046

A8K2U0
IQNNIFEIGVPKLKK

ANO2

691

Q9NQ90
GKQQFDLENKFKPFT

PGM1

171

P36871
AQKQFKNFQIEVQKG

JAK1

491

P23458
TFFQAKKLLPQEKNV

PTPN3

306

P26045
VNQPFPFGDKEKNKL

ITPR2

846

Q14571
KLVQKNPAVQFLYQK

LTN1

651

O94822
TQQDVKKENPLQFKF

RDX

66

P35241
NQLFVNLKNVNPGKR

MEGF10

956

Q96KG7
NFKLPQDDLQGIQKI

MMP24

311

Q9Y5R2
FGKNPLKNFQQLNLA

NLRC4

931

Q9NPP4
RKQKVLGPNQKLKFN

MTMR10

116

Q9NXD2
KDFKGKAQKQVQFNP

FREM2

1816

Q5SZK8
IPKIQKLLQDFFNGK

HSPA2

346

P54652
NILKNPQFVFDIKKT

PLXNC1

1421

O60486
QNNKLFLESKPKQEF

DEPDC1

451

Q5TB30
VKAPQGKNQKSFVFI

PLCG2

861

P16885
GKNQKSFVFILEPKQ

PLCG2

866

P16885
LKGNFPFKIVQDTKN

PCDHGB3

386

Q9Y5G1
PVAFKLVQQNQLKKG

MOCS1

516

Q9NZB8
LTLQPEQKFQKVKGF

GBA

106

P04062
KQLNKGTFKEQNDKP

PXN

566

P49023
QTFKVFQKNQVGPCK

DNAH3

591

Q8TD57
QFGVPLARNQLIQKK

GCDH

321

Q92947
LFKPVRNNIQQVFQK

COG3

781

Q96JB2
LPVQENFLLKFQGIK

CALB1

171

P05937
GKNKVPELQKFFQKA

COX7A2L

56

O14548
KKGEGLPNFDNNNIK

DNAJB11

301

Q9UBS4
IPVDKLVKGKFQDNF

MAPRE1

91

Q15691
GTEQFNQKPKKGIQF

GBF1

706

Q92538
NQKPKKGIQFLQEKG

GBF1

711

Q92538
PKVQKLLQDFFNGKE

HSPA6

346

P17066
FQKVLQLYPNNKAAK

FKBP4

376

Q02790
LKKFLGFVVDPNQVN

HELZ2

2581

Q9BYK8
PIGKKLFQQFLQSAE

GRK1

66

Q15835
QFKTQKVQDFRPNQK

DSEL

41

Q8IZU8
NVKQIFGFESNKKNL

DYSF

401

O75923
KNNFQAQLEFKLKPF

OSBPL5

561

Q9H0X9
FKRVPSINQKIVKNN

RPGR

956

Q92834
IGVIIDNFNQQKKKL

SCN4A

1291

P35499
FLEQNGQLGKPLAKK

SYNE1

5486

Q8NF91
KITQLKIENNPFAKG

TBX5

221

Q99593
KLLQFLAGQQVNPTK

HUS1

236

O60921
NPKFLQEKVKQYFKN

PITRM1

481

Q5JRX3
IGVIIDNFNQQKKKL

SCN5A

1466

Q14524
IIDNFNQQKKKLGGQ

SCN9A

1456

Q15858
NKGKPIFEVNKQDIY

SCYL2

261

Q6P3W7
NLQKSQFFKGLPKVL

SCYL2

346

Q6P3W7
VIIDNFNQQKKKFGG

SCN3A

1466

Q9NY46
SNNFQKPRNIKGKQE

MYH6

561

P13533
VIIDNFNQQKKKFGG

SCN1A

1481

P35498
LENKVKVQGFKNGPL

CLEC10A

11

Q8IUN9
RNVLLFKKQNPGKFC

RETREG3

156

Q86VR2
AIAKPINKSQFIKQQ

ZNF615

181

Q8N8J6
LNKNFTNVKNAAKPL

ZNF876P

31

Q49A33
QFANQNLSKKIPGVK

ZNF136

86

P52737
KKIILNAVFGFINNP

TOR1A

76

O14656
ANGSNVQLQLKFKFP

TMPRSS11B

106

Q86T26
PQNEPQIKNQFNKKL

SRFBP1

371

Q8NEF9
VIIDNFNQQKKKLGG

SCN10A

1416

Q9Y5Y9
GVKLKKVQEQEFNPL

SPIRE2

256

Q8WWL2
QNFELQPKLKQVFGK

TRPM3

191

Q9HCF6
APKDFNFQLKTGQKI

PISD

386

Q9UG56
KNAKDLPKLNQGQFI

TBC1D9

1016

Q6ZT07
VIIDNFNQQKKKFGG

SCN2A

1471

Q99250
GVIIDNFNQQKKKFG

SCN8A

1461

Q9UQD0
GLQNFEMQPKLKQVF

TRPM1

106

Q7Z4N2
VNKPNAVFKLKQGKE

ZNF25

51

P17030
NQNKPLSRVVFINKK

ZNF484

131

Q5JVG2
KPLQDQNELFGKIQA

SF3A3

201

Q12874
KKFQNKLLQTALFQP

TTC23

26

Q5W5X9
QNKLKKDFPKQFDQV

ZMYM4

131

Q5VZL5
QKLFGPDVKNQDVKR

WDR64

61

B1ANS9
QKGKTFLALINQVFP

MYO6

36

Q9UM54