Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionacetylcholine receptor regulator activity

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.10e-10271117GO:0030548
GeneOntologyMolecularFunctionneurotransmitter receptor regulator activity

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.46e-10281117GO:0099602
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1 NCF1C NCF1B

1.95e-05101113GO:0016176
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1 NCF1C NCF1B

3.55e-05121113GO:0016175
GeneOntologyMolecularFunctionSH3 domain binding

INPP5D NCF1 SOCS7 CABYR NCF1C NCF1B

1.48e-041431116GO:0017124
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1 NCF1C NCF1B

1.78e-04201113GO:0050664
GeneOntologyMolecularFunctionkinase binding

SPDYE1 NOL3 RB1 SPDYE18 RYR2 TAOK2 SPDYE3 SPDYE2 SPDYE21 PRKCSH SPDYE5 SPDYE2B SPDYE6 SPDYE16

9.59e-0496911114GO:0019900
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

NCF1 NCF1C NCF1B

9.61e-04351113GO:0043325
GeneOntologyMolecularFunctioncollagen binding

P3H4 ANTXR1 PODN TNXB

1.08e-03811114GO:0005518
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

3.45e-11251067GO:0045737
GeneOntologyBiologicalProcesspositive regulation of cyclin-dependent protein kinase activity

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

8.39e-11281067GO:1904031
GeneOntologyBiologicalProcessregulation of cyclin-dependent protein serine/threonine kinase activity

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

6.35e-07961067GO:0000079
GeneOntologyBiologicalProcessmuscle system process

CACNA1S PSEN2 NOL3 NCF1 APBB1 ARHGEF11 SELENON CERT1 RYR2 CLIC2 SCN2A FOXP1 NCF1C NCF1B

8.14e-0754710614GO:0003012
GeneOntologyBiologicalProcessregulation of cyclin-dependent protein kinase activity

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

8.38e-071001067GO:1904029
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

NCF1 NCF1C NCF1B

1.31e-0651063GO:0070946
GeneOntologyBiologicalProcesscollagen fibril organization

ADAMTS19 RB1 COLGALT2 SELENON P3H4 TNXB

2.61e-06761066GO:0030199
GeneOntologyBiologicalProcessNADP catabolic process

NCF1 NCF1C NCF1B

4.55e-0671063GO:0006742
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1 NCF1C NCF1B

4.55e-0671063GO:0070947
GeneOntologyBiologicalProcessmuscle contraction

CACNA1S PSEN2 NCF1 APBB1 ARHGEF11 CERT1 RYR2 CLIC2 SCN2A NCF1C NCF1B

6.79e-0640010611GO:0006936
GeneOntologyBiologicalProcessmaintenance of location in cell

CACNA1S JPH4 NOL3 SELENON RYR2 MPRIP CLIC2 TNRC6A PDIA2

7.68e-062591069GO:0051651
GeneOntologyBiologicalProcesspositive regulation of cell cycle

SPDYE1 RB1 SRPK2 SPAG5 EIF4G1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

8.00e-0640710611GO:0045787
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

2.11e-05111063GO:0060264
GeneOntologyBiologicalProcesscellular response to caffeine

CACNA1S SELENON RYR2

2.11e-05111063GO:0071313
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

3.63e-05131063GO:0002536
GeneOntologyBiologicalProcessmaintenance of location

CACNA1S JPH4 NOL3 SELENON RYR2 MPRIP CLIC2 G3BP2 TNRC6A PDIA2

3.76e-0539610610GO:0051235
GeneOntologyBiologicalProcessregulation of muscle system process

CACNA1S NOL3 NCF1 SELENON RYR2 CLIC2 FOXP1 NCF1C NCF1B

3.80e-053171069GO:0090257
GeneOntologyBiologicalProcesscellular response to purine-containing compound

CACNA1S SELENON RYR2

4.61e-05141063GO:0071415
GeneOntologyBiologicalProcesspositive regulation of protein serine/threonine kinase activity

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

6.28e-051931067GO:0071902
GeneOntologyBiologicalProcessneutrophil-mediated killing of bacterium

NCF1 NCF1C NCF1B

7.04e-05161063GO:0070944
GeneOntologyBiologicalProcessregulation of protein kinase activity

SPDYE1 PSEN2 RB1 NCF1 TAOK2 SPDYE3 SPDYE2 SPDYE5 SPDYE2B TNXB SPDYE6 SPDYE16

7.14e-0561110612GO:0045859
GeneOntologyBiologicalProcesspositive regulation of protein kinase activity

SPDYE1 NCF1 TAOK2 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

8.14e-053501069GO:0045860
GeneOntologyBiologicalProcessregulation of protein serine/threonine kinase activity

SPDYE1 RB1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B TNXB SPDYE6 SPDYE16

9.67e-053581069GO:0071900
GeneOntologyBiologicalProcessresponse to yeast

NCF1 NCF1C NCF1B

1.02e-04181063GO:0001878
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol

CACNA1S JPH4 NOL3 SELENON RYR2 CLIC2

1.08e-041461066GO:0051209
GeneOntologyBiologicalProcessnegative regulation of sequestering of calcium ion

CACNA1S JPH4 NOL3 SELENON RYR2 CLIC2

1.12e-041471066GO:0051283
GeneOntologyBiologicalProcesspositive regulation of molecular function

SPDYE1 RAPGEF6 PSEN2 RB1 NCF1 PPP1R3G TERF2IP RYR2 TBC1D17 TAOK2 CLIC2 EIF4G1 SPDYE3 SPDYE2 ANTXR1 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.14e-04143010619GO:0044093
GeneOntologyBiologicalProcessneutrophil-mediated killing of symbiont cell

NCF1 NCF1C NCF1B

1.20e-04191063GO:0070943
GeneOntologyBiologicalProcessregulation of sequestering of calcium ion

CACNA1S JPH4 NOL3 SELENON RYR2 CLIC2

1.21e-041491066GO:0051282
GeneOntologyBiologicalProcesssequestering of calcium ion

CACNA1S JPH4 NOL3 SELENON RYR2 CLIC2

1.40e-041531066GO:0051208
GeneOntologyBiologicalProcessrespiratory burst involved in defense response

NCF1 NCF1C NCF1B

1.41e-04201063GO:0002679
GeneOntologyBiologicalProcessregulation of monocyte differentiation

INPP5D FES FOXP1

1.41e-04201063GO:0045655
GeneOntologyBiologicalProcessextracellular matrix organization

ADAMTS19 RB1 APBB1 ITGA8 COLGALT2 SELENON P3H4 ANTXR1 TNXB

1.43e-043771069GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

ADAMTS19 RB1 APBB1 ITGA8 COLGALT2 SELENON P3H4 ANTXR1 TNXB

1.46e-043781069GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

ADAMTS19 RB1 APBB1 ITGA8 COLGALT2 SELENON P3H4 ANTXR1 TNXB

1.49e-043791069GO:0045229
GeneOntologyBiologicalProcessregulation of release of sequestered calcium ion into cytosol

JPH4 NOL3 SELENON RYR2 CLIC2

1.52e-04981065GO:0051279
GeneOntologyBiologicalProcesspositive regulation of collagen fibril organization

RB1 TNXB

1.56e-0441062GO:1904028
GeneOntologyBiologicalProcessregulation of neutrophil differentiation

INPP5D IKZF1

1.56e-0441062GO:0045658
GeneOntologyBiologicalProcessneutrophil mediated cytotoxicity

NCF1 NCF1C NCF1B

1.64e-04211063GO:0070942
GeneOntologyBiologicalProcessresponse to caffeine

CACNA1S SELENON RYR2

1.64e-04211063GO:0031000
GeneOntologyBiologicalProcessnegative regulation of smooth muscle contraction

NCF1 NCF1C NCF1B

1.89e-04221063GO:0045986
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

NCF1 NCF1C NCF1B

1.89e-04221063GO:0050665
GeneOntologyBiologicalProcessregulation of kinase activity

SPDYE1 PSEN2 RB1 NCF1 TAOK2 SPDYE3 SPDYE2 SPDYE5 SPDYE2B TNXB SPDYE6 SPDYE16

2.11e-0468610612GO:0043549
GeneOntologyBiologicalProcessregulation of protein phosphorylation

SPDYE1 PSEN2 RB1 NCF1 TERF2IP MPRIP TAOK2 EIF4G1 SPDYE3 SPDYE2 KNDC1 SPDYE5 SPDYE2B TNXB SPDYE6 SPDYE16

2.14e-04113310616GO:0001932
GeneOntologyBiologicalProcessregulation of respiratory burst

NCF1 NCF1C NCF1B

2.17e-04231063GO:0060263
GeneOntologyBiologicalProcesspositive regulation of transferase activity

SPDYE1 NCF1 PPP1R3G TAOK2 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

2.17e-0449010610GO:0051347
GeneOntologyBiologicalProcessregulation of cell cycle

SPDYE1 RB1 APBB1 SRPK2 DPF2 SPAG5 TAOK2 RECQL4 ANAPC2 EIF4G1 SPDYE3 SPDYE2 SPDYE5 DOT1L SPDYE2B SPDYE6 SPDYE16

2.20e-04125610617GO:0051726
GeneOntologyBiologicalProcesspositive regulation of kinase activity

SPDYE1 NCF1 TAOK2 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

2.43e-044051069GO:0033674
GeneOntologyBiologicalProcessregulation of transferase activity

SPDYE1 PSEN2 RB1 NCF1 PPP1R3G TAOK2 SPDYE3 SPDYE2 SPDYE5 SPDYE2B TNXB SPDYE6 SPDYE16

2.63e-0481010613GO:0051338
GeneOntologyBiologicalProcessregulation of ryanodine-sensitive calcium-release channel activity

JPH4 SELENON CLIC2

3.15e-04261063GO:0060314
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

SPDYE1 NCF1 MPRIP TAOK2 EIF4G1 SPDYE3 SPDYE2 KNDC1 SPDYE5 SPDYE2B SPDYE6 SPDYE16

3.44e-0472410612GO:0001934
GeneOntologyBiologicalProcessregulation of myeloid leukocyte differentiation

FSTL3 RB1 INPP5D IKZF1 FES FOXP1

3.57e-041821066GO:0002761
GeneOntologyBiologicalProcessregulation of phosphorylation

SPDYE1 PSEN2 RB1 NCF1 TERF2IP MPRIP TAOK2 EIF4G1 SPDYE3 SPDYE2 KNDC1 SPDYE5 SPDYE2B TNXB SPDYE6 SPDYE16

5.13e-04122610616GO:0042325
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

CACNA1S JPH4 PSEN2 NOL3 SELENON RYR2 GRID2IP CLIC2

5.34e-043591068GO:0006874
GeneOntologyBiologicalProcessregulation of protein modification process

SPDYE1 PSEN2 MYCBP2 RB1 NCF1 TERF2IP MPRIP TAOK2 PARP10 EIF4G1 SPDYE3 SPDYE2 KNDC1 SPDYE5 SPDYE2B TNXB SPDYE6 SPDYE16

5.51e-04148810618GO:0031399
GeneOntologyBiologicalProcessregulation of muscle contraction

CACNA1S NCF1 RYR2 CLIC2 NCF1C NCF1B

6.20e-042021066GO:0006937
GeneOntologyBiologicalProcessregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum

NOL3 RYR2 CLIC2

6.43e-04331063GO:0010880
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

SPDYE1 NCF1 MPRIP TAOK2 EIF4G1 SPDYE3 SPDYE2 KNDC1 SPDYE5 SPDYE2B SPDYE6 SPDYE16

6.67e-0478010612GO:0042327
GeneOntologyBiologicalProcessnegative regulation of muscle contraction

NCF1 NCF1C NCF1B

7.66e-04351063GO:0045932
GeneOntologyBiologicalProcessmonocyte differentiation

INPP5D FES FOXP1

7.66e-04351063GO:0030224
GeneOntologyBiologicalProcesspositive regulation of catalytic activity

SPDYE1 RAPGEF6 PSEN2 NCF1 PPP1R3G TBC1D17 TAOK2 SPDYE3 SPDYE2 ANTXR1 SPDYE5 SPDYE2B SPDYE6 SPDYE16

7.83e-04102810614GO:0043085
GeneOntologyBiologicalProcesscalcium ion homeostasis

CACNA1S JPH4 PSEN2 NOL3 SELENON RYR2 GRID2IP CLIC2

9.00e-043891068GO:0055074
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1S JPH4 NOL3 SELENON RYR2 CLIC2

9.01e-042171066GO:0097553
GeneOntologyBiologicalProcessstriated muscle contraction

CACNA1S PSEN2 ARHGEF11 RYR2 CLIC2 SCN2A

9.01e-042171066GO:0006941
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by sarcoplasmic reticulum

NOL3 RYR2 CLIC2

9.03e-04371063GO:0014808
GeneOntologyBiologicalProcessregulation of collagen fibril organization

RB1 TNXB

9.20e-0491062GO:1904026
GeneOntologyBiologicalProcessmitochondrion-endoplasmic reticulum membrane tethering

PSEN2 SELENON

9.20e-0491062GO:1990456
GeneOntologyBiologicalProcessregulation of calcium ion transmembrane transport

JPH4 PSEN2 NOL3 SELENON RYR2 CLIC2

9.22e-042181066GO:1903169
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1S JPH4 PSEN2 NOL3 SELENON RYR2 CLIC2 GRIN3B

9.46e-043921068GO:0070588
GeneOntologyBiologicalProcesskilling by host of symbiont cells

NCF1 NCF1C NCF1B

9.76e-04381063GO:0051873
GeneOntologyBiologicalProcesspositive regulation of protein modification process

SPDYE1 MYCBP2 NCF1 MPRIP TAOK2 EIF4G1 SPDYE3 SPDYE2 KNDC1 SPDYE5 SPDYE2B SPDYE6 SPDYE16

1.03e-0393710613GO:0031401
GeneOntologyBiologicalProcessrelease of sequestered calcium ion into cytosol by endoplasmic reticulum

NOL3 RYR2 CLIC2

1.05e-03391063GO:1903514
GeneOntologyBiologicalProcesscellular response to alkaloid

CACNA1S SELENON RYR2

1.14e-03401063GO:0071312
GeneOntologyBiologicalProcessmyeloid leukocyte differentiation

PSEN2 FSTL3 RB1 INPP5D IKZF1 FES FOXP1

1.15e-033121067GO:0002573
GeneOntologyBiologicalProcessleukotriene metabolic process

NCF1 NCF1C NCF1B

1.22e-03411063GO:0006691
GeneOntologyBiologicalProcessregulation of calcium ion transmembrane transporter activity

JPH4 SELENON RYR2 CLIC2

1.30e-03921064GO:1901019
GeneOntologyBiologicalProcessrespiratory burst

NCF1 NCF1C NCF1B

1.40e-03431063GO:0045730
GeneOntologyBiologicalProcessregulation of calcium ion transport

JPH4 PSEN2 NOL3 SELENON RYR2 CLIC2 GRIN3B

1.40e-033231067GO:0051924
GeneOntologyBiologicalProcesssarcoplasmic reticulum calcium ion transport

NOL3 RYR2 CLIC2

1.50e-03441063GO:0070296
GeneOntologyCellularComponentNADPH oxidase complex

NCF1 NCF1C NCF1B

1.03e-04181083GO:0043020
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

5.26e-066913MP:0013254
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

5.26e-066913MP:0003184
MousePhenoliver abscess

NCF1 NCF1C NCF1B

9.17e-067913MP:0003332
MousePhenoimpaired granulocyte bactericidal activity

NCF1 NCF1C NCF1B

3.10e-0510913MP:0005074
MousePhenoabnormal long bone metaphysis morphology

INPP5D RECQL4 ANTXR1 LTBP3

1.16e-0439914MP:0000133
DomainSpy1

SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16

9.74e-17111028PF11357
DomainSpeedy

SPDYE1 SPDYE3 SPDYE2 SPDYE21 SPDYE5 SPDYE2B SPDYE6 SPDYE16

9.74e-17111028IPR020984
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1 NCF1C NCF1B

1.09e-059733MM14524
Pubmed

Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene.

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

9.97e-179111736272447
Pubmed

Identification and comparative analysis of multiple mammalian Speedy/Ringo proteins.

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

4.70e-1513111715611625
Pubmed

Characterization of a new family of cyclin-dependent kinase activators.

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6 SPDYE16

5.27e-1417111715574121
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1 NCF1C NCF1B

3.16e-083111318036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1 NCF1C NCF1B

3.16e-083111310678931
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1 NCF1C NCF1B

3.16e-083111327044504
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1 NCF1C NCF1B

3.16e-083111317167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1 NCF1C NCF1B

3.16e-083111324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1 NCF1C NCF1B

3.16e-083111310891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1 NCF1C NCF1B

3.16e-083111325474113
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1 NCF1C NCF1B

3.16e-083111318787174
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1 NCF1C NCF1B

3.16e-083111326209274
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1 NCF1C NCF1B

3.16e-083111324873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1 NCF1C NCF1B

3.16e-083111322184329
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1 NCF1C NCF1B

3.16e-083111311018074
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1 NCF1C NCF1B

3.16e-083111333545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1 NCF1C NCF1B

3.16e-083111320142487
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

3.16e-08311139116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1 NCF1C NCF1B

3.16e-083111320686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1 NCF1C NCF1B

3.16e-083111321570954
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1 NCF1C NCF1B

3.16e-083111325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1 NCF1C NCF1B

3.16e-083111339357591
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1 NCF1C NCF1B

3.16e-083111312958309
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1 NCF1C NCF1B

3.16e-083111311435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1 NCF1C NCF1B

3.16e-083111331118934
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1 NCF1C NCF1B

3.16e-083111323482812
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1 NCF1C NCF1B

3.16e-083111316041040
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1 NCF1C NCF1B

3.16e-083111310085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1 NCF1C NCF1B

3.16e-083111310987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1 NCF1C NCF1B

3.16e-083111321435178
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1 NCF1C NCF1B

3.16e-083111318703411
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1 NCF1C NCF1B

3.16e-083111329228045
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1 NCF1C NCF1B

3.16e-083111317307863
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1 NCF1C NCF1B

3.16e-083111322155727
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1 NCF1C NCF1B

3.16e-083111327829407
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1 NCF1C NCF1B

3.16e-083111324576409
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1 NCF1C NCF1B

3.16e-083111322376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1 NCF1C NCF1B

3.16e-083111323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1 NCF1C NCF1B

3.16e-083111328274989
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1 NCF1C NCF1B

3.16e-083111326645958
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1 NCF1C NCF1B

3.16e-083111312364355
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1 NCF1C NCF1B

3.16e-083111324549323
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1 NCF1C NCF1B

3.16e-083111334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1 NCF1C NCF1B

3.16e-083111328467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1 NCF1C NCF1B

3.16e-083111310670582
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1 NCF1C NCF1B

3.16e-083111320881184
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1 NCF1C NCF1B

3.16e-083111326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1 NCF1C NCF1B

3.16e-083111319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1 NCF1C NCF1B

3.16e-083111320864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1 NCF1C NCF1B

3.16e-083111323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1 NCF1C NCF1B

3.16e-083111334572995
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1 NCF1C NCF1B

3.16e-083111317114280
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1 NCF1C NCF1B

3.16e-083111319168575
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1 NCF1C NCF1B

3.16e-083111325989352
Pubmed

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

NCF1 NCF1C NCF1B

3.16e-083111319503084
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1 NCF1C NCF1B

3.16e-083111317404617
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1 NCF1C NCF1B

3.16e-083111317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1 NCF1C NCF1B

3.16e-083111336592568
Pubmed

Genetic requirement of p47phox for superoxide production by murine microglia.

NCF1 NCF1C NCF1B

3.16e-083111311156938
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1 NCF1C NCF1B

3.16e-083111330504842
Pubmed

Genomic structure of the human p47-phox (NCF1) gene.

NCF1 NCF1C NCF1B

3.16e-083111310772875
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1 NCF1C NCF1B

3.16e-083111327798190
Pubmed

Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

NCF1 NCF1C NCF1B

3.16e-083111320702812
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1 NCF1C NCF1B

3.16e-083111333705493
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1 NCF1C NCF1B

3.16e-083111323965970
Pubmed

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

NCF1 NCF1C NCF1B

3.16e-083111326455429
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1 NCF1C NCF1B

3.16e-083111315513930
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1 NCF1C NCF1B

3.16e-083111315626477
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1 NCF1C NCF1B

3.16e-083111315033459
Pubmed

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

NCF1 NCF1C NCF1B

3.16e-083111319077231
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1 NCF1C NCF1B

3.16e-083111320828610
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1 NCF1C NCF1B

3.16e-083111320817944
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1 NCF1C NCF1B

3.16e-083111322319452
Pubmed

Early determinants of H2O2-induced endothelial dysfunction.

NCF1 NCF1C NCF1B

3.16e-083111316895801
Pubmed

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis.

NCF1 NCF1C NCF1B

3.16e-083111320690191
Pubmed

Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis.

NCF1 NCF1C NCF1B

3.16e-083111316772302
Pubmed

Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice.

NCF1 NCF1C NCF1B

3.16e-083111332504071
Pubmed

Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

NCF1 NCF1C NCF1B

3.16e-083111316280459
Pubmed

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

NCF1 NCF1C NCF1B

3.16e-083111318185592
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1 NCF1C NCF1B

3.16e-083111336853827
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1 NCF1C NCF1B

3.16e-083111323024271
Pubmed

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

NCF1 NCF1C NCF1B

3.16e-083111321253614
Pubmed

Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.

NCF1 NCF1C NCF1B

3.16e-083111325873172
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1 NCF1C NCF1B

3.16e-083111315310853
Pubmed

Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.

NCF1 NCF1C NCF1B

3.16e-083111331393787
Pubmed

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.

NCF1 NCF1C NCF1B

3.16e-083111310725280
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1 NCF1C NCF1B

3.16e-083111334970267
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1 NCF1C NCF1B

3.16e-083111325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1 NCF1C NCF1B

3.16e-083111314993144
Pubmed

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

NCF1 NCF1C NCF1B

3.16e-083111322050439
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1 NCF1C NCF1B

3.16e-083111312031896
Pubmed

NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.

NCF1 NCF1C NCF1B

3.16e-083111311249873
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1 NCF1C NCF1B

3.16e-083111315936744
Pubmed

NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation.

NCF1 NCF1C NCF1B

3.16e-083111317220182
Pubmed

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.

NCF1 NCF1C NCF1B

3.16e-083111325628043
Pubmed

The p47phox mouse knock-out model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

3.16e-08311137650482
Pubmed

Disseminated trichosporonosis in a murine model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

3.16e-083111312868577
Pubmed

Mechanism of endothelial cell NADPH oxidase activation by angiotensin II. Role of the p47phox subunit.

NCF1 NCF1C NCF1B

3.16e-083111312560337
Pubmed

NADPH oxidase mediates striatal neuronal injury after transient global cerebral ischemia.

NCF1 NCF1C NCF1B

3.16e-083111320859296
Pubmed

Inhibition of endothelial Nox2 activation by LMH001 protects mice from angiotensin II-induced vascular oxidative stress, hypertension and aortic aneurysm.

NCF1 NCF1C NCF1B

3.16e-083111335276443
InteractionBCR interactions

JPH4 RB1 INPP5D DPF2 VIRMA TAOK2 G3BP2 RECQL4 FES

5.71e-062441069int:BCR
InteractionDYRK1A interactions

MYCBP2 RB1 MAGEH1 SRPK2 ICE1 VIRMA MPRIP ANAPC2 EIF4G1 KNDC1 PPP1R18 AFF1 LTBP3

6.59e-0655210613int:DYRK1A
InteractionTJP2 interactions

JPH4 RAPGEF6 INPP5D SRPK2 VIRMA ARHGAP12 TNRC6A ANTXR1 DNMBP

2.15e-052881069int:TJP2
InteractionFOXK2 interactions

SETD1B RB1 SRPK2 IKZF1 VIRMA TERF2IP BPTF EIF5B

2.51e-052251068int:FOXK2
InteractionKDM1A interactions

RAPGEF6 MYCBP2 RB1 IKZF1 ICE1 VIRMA TERF2IP SPAG5 CFAP100 ZFHX4 PELP1 RECQL4 ZNF641 TNRC6A RNF10 FOXP1

3.20e-0594110616int:KDM1A
InteractionBNC2 interactions

RB1 VIRMA FOXP1

3.89e-05131063int:BNC2
InteractionH1-4 interactions

INSYN1 ZNF184 ITGA8 SRPK2 IKZF1 DPF2 VIRMA TNRC18 RBM19 RECQL4 EIF5B FOXP1 DOT1L

4.04e-0565610613int:H1-4
InteractionSRI interactions

CACNA1S PSEN2 SRPK2 RYR2 ANAPC2

5.70e-05781065int:SRI
InteractionTOGARAM1 interactions

SRPK2 VIRMA PRKCSH

6.15e-05151063int:TOGARAM1
Cytoband7q11.23

NCF1 SPDYE18 SPDYE5 NCF1C NCF1B

4.07e-069711157q11.23
CytobandEnsembl 112 genes in cytogenetic band chr7q11

NCF1 SPDYE18 SPDYE21 SPDYE5 NCF1C NCF1B SPDYE16

4.65e-062711117chr7q11
Cytoband7q22.1

SPDYE3 SPDYE2 SPDYE2B SPDYE6

1.70e-0411311147q22.1
CytobandEnsembl 112 genes in cytogenetic band chr7q22

SRPK2 SPDYE3 SPDYE2 SPDYE2B SPDYE6

2.01e-042191115chr7q22
GeneFamilySpeedy/RINGO cell cycle regulator family

SPDYE1 SPDYE3 SPDYE2 SPDYE5 SPDYE2B SPDYE6

4.09e-1212766756
CoexpressionGSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP

SETD1B RB1 RYR2 TAOK2 PELP1 TNRC6A DNMBP

5.87e-061661087M344
CoexpressionBYSTROEM_CORRELATED_WITH_IL5_DN

NCF1 IKZF1 EIF4G1 NCF1C NCF1B

1.48e-05751085MM605
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYCBP2 MPRIP BPTF G3BP2 ANKRD11 ANTXR1 FOXP1

4.44e-071901097d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellwk_20-22-Mesenchymal-Fibroblast-Adventitial_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ADAMTS19 FSTL3 SERPINF1 P3H4 ANTXR1 PODN TNXB

6.06e-071991097ab0589c068c24aa989bdca083504fbad0c15221d
ToppCellICU-NoSEP-Lymphocyte-T_NK-Treg|ICU-NoSEP / Disease, Lineage and Cell Type

IL32 RAPGEF6 ATCAY VSIG1 SLC29A2 MPRIP

2.66e-061591096d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FSTL3 SERPINF1 SCN2A PODN KATNIP LTBP3

6.35e-0618510961b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell3'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRRC39 FSTL3 ARHGEF11 SELENON TBC1D17 SPDYE3

7.18e-0618910967dad62bd50c197838058e89abd0ee387de3e83cd
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

ADAMTS19 SERPINF1 COLGALT2 ANTXR1 PODN TNXB

7.85e-061921096a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSTL3 INSYN1 SERPINF1 ANTXR1 LTBP3 TNXB

8.09e-0619310960a665531d581d4e3941e29d3f95569da8f166447
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS19 SERPINF1 COLGALT2 ANTXR1 PODN TNXB

8.09e-0619310969ab47b360bee1d4f1092c2269e58acebe9584021
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSTL3 INSYN1 SERPINF1 ANTXR1 LTBP3 TNXB

8.09e-06193109624ce1f37cca655415410d2403a52d1ebb3332280
ToppCellfacs-BAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 P3H4 ANTXR1 PODN LTBP3 TNXB

8.33e-061941096da45811ba07d746e7cba7ed78882b5d98ac7397d
ToppCellfacs-BAT-Fat-3m-Mesenchymal|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 P3H4 ANTXR1 PODN LTBP3 TNXB

8.33e-06194109676b8512fd92014b3ecc42b0a20d6d1df074cba2c
ToppCellfacs-BAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 P3H4 ANTXR1 PODN LTBP3 TNXB

8.33e-061941096ef0fa9daecd3bf43c6cf56345928cacdbee19779
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SERPINF1 ITGA8 RYR2 ANTXR1 PODN TNXB

8.83e-0619610967d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSTL3 SERPINF1 P3H4 ANTXR1 LTBP3 TNXB

9.09e-061971096b16add329bb35a558287ede51353010dde5bc029
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-Treg|ICU-NoSEP / Disease, condition lineage and cell class

IL32 RAPGEF6 ATCAY VSIG1 SLC29A2 MPRIP

9.36e-0619810961ed4dfe5565328cb0f7ef31e6b2f67dfbdf3e2ac
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 SELENON ANTXR1 PODN LTBP3 TNXB

9.36e-0619810960dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCellwk_15-18-Mesenchymal-Fibroblast-Adventitial_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ADAMTS19 FSTL3 SERPINF1 CERT1 P3H4 PODN

9.63e-0619910968de6d7b2067b22cb9b5f01aa56a3803aebc4406d
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

SRPK2 BPTF ANKRD11 EIF5B FOXP1 HPS5

9.63e-06199109653ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

SRPK2 TERF2IP BPTF ANKRD11 EIF5B HPS5

9.63e-061991096fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FSTL3 SERPINF1 ITGA8 RYR2 ANTXR1 TNXB

9.91e-0620010968c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FSTL3 SERPINF1 ITGA8 ANTXR1 PODN TNXB

9.91e-0620010966e3d1ae0ef84d3075afa40129a41169996462672
ToppCellCOVID-19|World / Disease, condition lineage and cell class

MYCBP2 IKZF1 BPTF RSAD2 G3BP2 ANKRD11

9.91e-0620010967dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADAMTS19 TRPC5OS PDIA2 CFAP44

1.09e-05561094ad76712e6a99072f9c6dab6d746db54f754e14fd
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Ntng1_(Entopeduncular_Nucleus_(Ent)_or_Zona_Incerta,_ventral_part_(ZIV)._State_signal?)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ADAMTS19 TRPC5OS PDIA2 CFAP44

1.09e-0556109420a2977f41d3ecbc4fbee7ecd6dfb4b7ce0e4bb7
ToppCell367C-Lymphocytic-ILC-ILC-3|367C / Donor, Lineage, Cell class and subclass (all cells)

IL32 ZNF184 TERF2IP PARP10 G3BP2

3.74e-0515310959d64aadbb4bb28469af1d728457b431e21577429
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SERPINF1 RECQL4 ZSCAN18 PODN TNXB

4.50e-0515910957ed659163f45e0c4df4782997c0786900c8186c8
ToppCell390C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ICE1 COLGALT2 ZNF398 ANTXR1 CFAP44

4.91e-05162109545be019b50e3727fc9d3fad2ff78e74e4f2d746b
ToppCell390C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ICE1 COLGALT2 ZNF398 ANTXR1 CFAP44

4.91e-051621095fbb0cc2b1434a340dc35058b77c73ea61004c252
ToppCellmild_COVID-19_(asymptomatic)-CD4+_T_naive|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

IL32 RAPGEF6 GAGE10 FOXP1 LTBP3

5.68e-05167109578d264af390bd89942ffbb2991dc94f50756d4c9
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA9 NCF1 IKZF1 SPAG5 FES

6.18e-051701095d582087a983fe20d811d92f0de0458f3cfd71d2b
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-macrophage|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA9 NCF1 IKZF1 SPAG5 FES

6.18e-051701095dfbe7ba11b867a4e10fa915f282a2e5cb2f5fb8c
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Myeloid-new-cluster|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA9 NCF1 IKZF1 SPAG5 FES

6.35e-051711095d0d92eb5152410c3b4dd4a3f1dc3cca0e18a85fd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA8 COLGALT2 ANTXR1 PODN TNXB

7.08e-051751095795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL32 TRPC5OS PCDH12 SPAG5 CABYR

7.68e-05178109560263c0bb9de3a57ba2ba543262a2ace0066fd85
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP100 KNDC1 KATNIP GRIN3B CFAP44

8.09e-05180109592fb01b91261b3103454924cde56add337b41844
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FSTL3 SERPINF1 PODN LTBP3 TNXB

8.09e-05180109539ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S NOL3 MAGEH1 P3H4 ANTXR1

8.30e-051811095cd46eba2e03fd15d8de8e875793ae2f51fa98b3b
ToppCelldroplet-Marrow-BM-30m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S NOL3 MAGEH1 P3H4 ANTXR1

8.30e-051811095c7d12c7de227c9433ec2303b8929e957b833f59b
ToppCelldroplet-Pancreas-Endocrine-21m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S INPP5D NCF1 IKZF1 PPP1R18

8.52e-051821095cf32603ad9b9882b0bb873327d58b50dd26a5bd3
ToppCelldroplet-Pancreas-Endocrine-21m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S INPP5D NCF1 IKZF1 PPP1R18

8.52e-05182109571cfd0b6d464e3e1b1cca34f423abdf699cda48a
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

RAPGEF6 PSEN2 RBM19 FES SPDYE16

8.75e-051831095310ad42b2b5d8ddd01d3a12db338f80ac1f5d08e
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RAPGEF6 PSEN2 RBM19 FES SPDYE16

8.75e-051831095fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1S NOL3 MAGEH1 P3H4 ANTXR1

8.97e-0518410951e54fd372c6e6a298f427b807c14cc49aaaffe80
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SERPINF1 ZFHX4 ANTXR1 PODN TNXB

9.20e-0518510956712512100ccef456d2e2bd201d0987986c92ac9
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP100 KNDC1 DNAI4 GRIN3B CFAP44

9.20e-0518510955e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SERPINF1 ZFHX4 ANTXR1 PODN TNXB

9.20e-0518510953b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

ADAMTS19 SERPINF1 ANTXR1 PODN TNXB

9.68e-0518710954ea486991f66c29728d127171a07b81404ec0b78
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

ITGA8 RYR2 ANTXR1 PODN TNXB

9.68e-051871095bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINF1 ZFHX4 ANTXR1 PODN TNXB

9.93e-051881095ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTS19 SERPINF1 PODN LTBP3 TNXB

9.93e-051881095bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AK9 CFAP100 KNDC1 DNAI4 CFAP44

1.02e-041891095057d7a03fdbe779122b203619a6f947f49b84d28
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS19 ZFHX4 ANTXR1 FRMPD3 TNXB

1.02e-041891095eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AK9 CFAP100 KNDC1 DNAI4 CFAP44

1.02e-0418910959f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 RYR2 ANTXR1 PODN TNXB

1.02e-0418910952a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS19 ZFHX4 ANTXR1 FRMPD3 TNXB

1.02e-04189109540764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AK9 CFAP100 KNDC1 DNAI4 CFAP44

1.02e-041891095e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

SERPINF1 ANTXR1 PODN FRMPD3 TNXB

1.04e-0419010957dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINF1 ZFHX4 ANTXR1 PODN TNXB

1.04e-041901095efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

ITGA8 RYR2 ANTXR1 PODN TNXB

1.04e-0419010953a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 RYR2 ANTXR1 PODN TNXB

1.04e-04190109596a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ADAMTS19 ZFHX4 ANTXR1 FRMPD3 TNXB

1.07e-0419110955271198116343c07202649889057e5774d7fdde3
ToppCell(3)_MNP-(3)_DC_1|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

SERPINF1 PPP1R3G CLIC2 G3BP2 HPS5

1.07e-041911095cf0ea54670ed478c3302ccfbee9f6b6706e49fcd
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AK9 CFAP100 KNDC1 DNAI4 CFAP44

1.07e-04191109596483adb97c81208aa513782550acd8a08b63866
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IL32 RAPGEF6 IKZF1 RSAD2 FOXP1

1.10e-04192109535557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCellCOPD-Lymphoid-T|World / Disease state, Lineage and Cell class

IL32 RAPGEF6 INPP5D IKZF1 RYR2

1.10e-041921095eb4909574fb5fc91399463523e2737095773200a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 SELENON ANTXR1 PODN TNXB

1.10e-041921095beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellCiliated-cil-3|World / Class top

NOL3 CFAP100 KNDC1 DNAI4 CFAP44

1.10e-0419210954989ebb8812b8af1870599acd932849122c05a29
ToppCellCOVID-19_Moderate-CD4+_T_activated|World / disease group, cell group and cell class

IL32 VSIG1 PARP10 RSAD2 FOXP1

1.12e-041931095c2a2a2c14a7085690262db5c2a70e38db67dee18
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MYCBP2 NCF1 BPTF NCF1C NCF1B

1.15e-041941095ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINF1 ZFHX4 ANTXR1 PODN TNXB

1.15e-041941095c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FSTL3 INSYN1 SERPINF1 LTBP3 TNXB

1.15e-0419410952d0cff9dc538a14518741e2a96d9d78442c81a72
ToppCellMild/Remission-B_activate-7|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYCBP2 NCF1 PARP10 RSAD2 FOXP1

1.15e-04194109501c97543972159a9468272da06e7e611e2c21fae
ToppCelldroplet-Heart-nan-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 ANTXR1 PODN LTBP3 TNXB

1.15e-04194109520a0439fa02c5f8107612e34c7ab54120b9b8573
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DMXL2 TNRC18 FES NCF1C NCF1B

1.18e-041951095b0dbaae86f5703ab62f925e0f36500274044884a
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 ANTXR1 PODN LTBP3 TNXB

1.18e-041951095613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCell3'-Pediatric_IBD|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL32 INPP5D NCF1 IKZF1 PPP1R18

1.18e-041951095728776511e1f40f127f80ef1eecda6d6ad082392
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 ANTXR1 PODN LTBP3 TNXB

1.18e-0419510959ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINF1 ZFHX4 ANTXR1 PODN TNXB

1.18e-0419510953c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

IL32 ITGA8 RYR2 PODN TNXB

1.18e-041951095e5b0afbea85575851cf9eb50a9ac42c67bbf3d7c
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FSTL3 SERPINF1 P3H4 RYR2 PODN

1.21e-041961095525d6c8a277364e624e7cc586275f8a891436b57
ToppCellCOPD-Lymphoid-T|COPD / Disease state, Lineage and Cell class

IL32 RAPGEF6 INPP5D IKZF1 RYR2

1.21e-04196109530e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 P3H4 ANTXR1 LTBP3 TNXB

1.21e-04196109559b5b5a0c123d0423abd19c312514849004b903b
ToppCelldistal-Hematologic-Interstitial_Macrophage-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DMXL2 SERPINF1 NCF1 NCF1C NCF1B

1.21e-041961095e4f40274df940e0996c555082f2bb4f99e5b0881
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

ITGA8 RYR2 ANTXR1 PODN TNXB

1.21e-041961095bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADAMTS19 JPH4 SERPINF1 COLGALT2 TNXB

1.21e-041961095eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 IKZF1 TERF2IP G3BP2 FOXP1

1.24e-041971095ef2d1f56acd0be43e69bba7f73f6909ba87f1cb3
ToppCell3'-Child04-06|3' / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL32 INPP5D NCF1 IKZF1 PPP1R18

1.24e-0419710955da92d069bb32ede5e8f30c5b68c4d0790373467
ToppCell390C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

IL32 NOL3 SERPINF1 IKZF1 CLIC2

1.24e-041971095311438418f3d697e54222da111014c887fd815f5
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SERPINF1 ITGA8 ZFHX4 ANTXR1 LTBP3

1.24e-0419710953fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSTL3 SERPINF1 ZFHX4 PODN TNXB

1.27e-041981095abac765c4f6864bdb1700bc546c3b9771edc25c3
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lung / Location, Cell class and cell subclass

SERPINF1 ITGA8 ANTXR1 PODN TNXB

1.27e-0419810952d7842f352273b6b823c86eb548b9f4a4cddf0ae
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

ITGA8 RYR2 ANTXR1 PODN TNXB

1.27e-04198109526e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4|bone_marrow / Manually curated celltypes from each tissue

IL32 RAPGEF6 VSIG1 IKZF1 FOXP1

1.27e-041981095f2d85d7ca0e867d20ad4d2b1cbbfd91a066c1a03
ToppCellwk_20-22|World / Celltypes from embryonic and fetal-stage human lung

IL32 NCF1 IKZF1 PARP10 PPP1R18

1.27e-04198109556eb765773a1a27a44262a447df7cfae8a9db90d
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINF1 P3H4 ANTXR1 LTBP3 TNXB

1.27e-0419810951b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ITGA8 RYR2 ANTXR1 PODN TNXB

1.27e-0419810958f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCell3'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSTL3 SERPINF1 ZFHX4 PODN TNXB

1.27e-041981095ff57addcbdd53e5d2d0c80ec76b5eab3b3a67ca2
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4|lymph-node_spleen / Manually curated celltypes from each tissue

IL32 RAPGEF6 APBB1 IKZF1 FOXP1

1.27e-0419810952cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL32 IKZF1 TERF2IP G3BP2 FOXP1

1.27e-04198109533a3b279c9ff3b762e52d060dae062167ca2239b
ToppCell3'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FSTL3 SERPINF1 ZFHX4 PODN TNXB

1.27e-041981095698166b4ca173176ed563af6a1efc8c7d0a18e0b
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1 NCF1C NCF1B

3.65e-075993DOID:3265 (implicated_via_orthology)
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1 NCF1C NCF1B

7.88e-0612993DOID:7148 (implicated_via_orthology)
DiseasePrecursor B-cell lymphoblastic leukemia

IKZF1 AFF1 FOXP1

4.66e-0521993C1292769
DiseaseRare disease with malignant hyperthermia

CACNA1S SELENON

6.66e-054992cv:C5681128
Diseaseretinoblastoma (is_implicated_in)

RB1 SERPINF1

6.66e-054992DOID:768 (is_implicated_in)
Diseaseeosinophil count

ADAMTS19 RAPGEF6 PSEN2 INPP5D IKZF1 BPTF PELP1 ANKRD11 ZNF398 PPP1R18 ANTXR1 FOXP1 PRKCSH LTBP3 TNXB

1.29e-0414889915EFO_0004842
Diseasecognitive function measurement, self reported educational attainment

DMXL2 MYCBP2 ZNF184 SRPK2 TNRC6A FOXP1 TNXB

1.98e-04355997EFO_0004784, EFO_0008354
DiseaseBurkitt Lymphoma

IKZF1 AFF1 FOXP1

2.41e-0436993C0006413
DiseaseNeurodevelopmental Disorders

CERT1 SCN2A ANKRD11 FOXP1

2.77e-0493994C1535926
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

INSYN1 ZNF184 TERF2IP RYR2 BPTF RBM19 SCN2A TNRC6A FOXP1 HPS5

3.63e-048019910EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseUveitis

SERPINF1 RBP3

3.95e-049992C0042164
DiseaseHermanski-Pudlak Syndrome

BLOC1S3 HPS5

4.93e-0410992C0079504
DiseaseHermansky-Pudlak syndrome

BLOC1S3 HPS5

4.93e-0410992cv:C0079504
DiseaseEpilepsy

PCDH12 CERT1 SCN2A ANKRD11

5.06e-04109994C0014544
Diseasemetabolic syndrome

CERT1 TAOK2 BPTF TNRC6A AFF1

5.81e-04200995EFO_0000195
DiseaseCongenital myopathy (disorder)

CACNA1S SELENON

7.20e-0412992C0270960
DiseaseInfantile Severe Myoclonic Epilepsy

SCN2A TNRC6A

8.48e-0413992C0751122
Diseasesexual dimorphism measurement

RAPGEF6 COLGALT2 CERT1 TAOK2 BPTF PARP10 FER1L4 TNRC6A ANKRD11 LTBP3 DOT1L

1.21e-0311069911EFO_0021796
Diseaseosteosarcoma (is_implicated_in)

RB1 SERPINF1

1.30e-0316992DOID:3347 (is_implicated_in)
Diseasebasophil count, eosinophil count

INPP5D IKZF1 BPTF ZNF398 TNXB

1.34e-03241995EFO_0004842, EFO_0005090
DiseasePR interval

MYCBP2 ZNF184 P3H4 RYR2 TJAP1 AFF1 FOXP1

1.42e-03495997EFO_0004462
Diseaseneutrophil count

MYCBP2 INPP5D SRPK2 IKZF1 TNRC6A FES ANKRD11 ZNF398 AFF1 FOXP1 GRIN3B TNXB

2.28e-0313829912EFO_0004833
Diseasetooth agenesis

CACNA1S FOXP1

2.46e-0322992EFO_0005410
DiseaseEpilepsy, Cryptogenic

CERT1 SCN2A ANKRD11

2.68e-0382993C0086237
DiseaseAwakening Epilepsy

CERT1 SCN2A ANKRD11

2.68e-0382993C0751111
DiseaseAura

CERT1 SCN2A ANKRD11

2.68e-0382993C0236018
Diseasewaist-hip ratio

DMXL2 MYCBP2 SRPK2 MPRIP TAOK2 BPTF SCN2A TNRC6A PRKCSH LTBP3 DOT1L

2.72e-0312269911EFO_0004343
Diseaseneuroimaging measurement, brain volume measurement

ZNF184 ARHGEF11 BPTF ZNF398 ANTXR1

2.81e-03286995EFO_0004346, EFO_0006930
Diseasevital capacity

ADAMTS19 CACNA1S ZNF184 AK9 RYR2 ANTXR1 AFF1 FOXP1 LTBP3 DOT1L TNXB

2.89e-0312369911EFO_0004312
DiseaseAutism Spectrum Disorders

RYR2 ANKRD11 FOXP1

2.96e-0385993C1510586

Protein segments in the cluster

PeptideGeneStartEntry
EDDSGEPEDWVPDPV

ANAPC2

471

Q9UJX6
GEAEPVEESLAPPEE

ANKRD11

2151

Q6UB99
PPPAEESEEEDDDGL

ANTXR1

356

Q9H6X2
EVPEPSDRSEEPETP

CCSMST1

111

Q4G0I0
DSDVFHGEPEPEELP

ARHGEF11

1116

O15085
TSPEPGELESEPEEE

CCDC96

36

Q2M329
VDTPVGEEEIGPDED

DNMBP

226

Q6XZF7
PEGLTAPEIEPEGES

CABYR

476

O75952
DEEEEEDLSSPPGLP

APBB1

166

O00213
APPGDDILEEEEEID

DMXL2

136

Q8TDJ6
SPLTSDEEPGSEDEP

DOT1L

1181

Q8TEK3
PDDDPEQGKSEEPTE

BPTF

611

Q12830
FGIETEPIPEDIEDP

CFAP44

906

Q96MT7
EEDLPGEEDLPEVKP

CA9

86

Q16790
EDPEQDSGPEDLPLV

RB1

31

P06400
EKDPAEPETVPDGET

RBM19

681

Q9Y4C8
EPETVPDGETPEDEN

RBM19

686

Q9Y4C8
PPPSEGEEDEELESQ

ADAMTS19

106

Q8TE59
EEEEVGLPPEPAHTE

INSYN1

211

Q2T9L4
DPEQEEGPLDPEEDL

PCDH12

1011

Q9NPG4
GSEEDPETESGPPVE

CERT1

11

Q9Y5P4
AEEEPVLVLSPEEPG

PODN

46

Q7Z5L7
PTEKQEAELGEPDPE

MPRIP

511

Q6WCQ1
DDLSGPEEDPSTPEE

MAGEH1

46

Q9H213
PVPSSPTEEEEEEEE

PRKCSH

306

P14314
AVPDEIPPLEGDEDA

HSP90AB3P

576

Q58FF7
SIEEDILSEPEPEDP

KATNIP

206

O60303
DEDLPRPLPEETGVE

ATCAY

21

Q86WG3
PGLEEDIPDPEELDW

FER1L4

1096

A9Z1Z3
EEDTEEEKEVTSPPP

HPS5

591

Q9UPZ3
SLREEEGEDEEPLPP

JPH4

541

Q96JJ6
LPPSEGTDEEEEREL

LRRC39

286

Q96DD0
EPLDSPDETEDPEPN

NCF1

211

P14598
EDPEAQPPSTEEEGL

FAM205C

316

A6NFA0
KEEPLDPEEAEGPLS

FOXP1

636

Q9H334
FSDEVEPATPEEGEP

GAGE2D;

31

Q9UEU5
FSDEVEPATPEEGEP

GAGE2A

31

Q6NT46
EEPPEEEIPKEDGIL

PDIA2

31

Q13087
ESPPVSDTPDEGDEP

IKZF1

16

Q13422
EEPSAPPTLLEEETE

PELP1

1056

Q8IZL8
EEETEDGSDKVQPPP

PELP1

1066

Q8IZL8
EPEEEPHKEEEVGPL

ITGA8

806

P53708
LEPLDSPDETEDPEP

NCF1B

211

A6NI72
LEPLDSPDETEDPEP

NCF1C

186

A8MVU1
TDEGIEEEIPDSPGI

ARHGAP12

581

Q8IWW6
PDVEDPATEEPGESF

IL32

136

P24001
TDGGEEDLPEPVEPS

ICE1

1356

Q9Y2F5
EPEPELDLESEPTPE

GRID2IP

476

A4D2P6
FPGDDEEDEPEIPLS

CACNA1S

741

Q13698
TPEEPPGGESAEEEE

FSTL3

246

O95633
SLPPPGSEEEEEEED

FRMPD3

676

Q5JV73
EEPLEESSHEPEPEP

G3BP2

186

Q9UN86
FSDEVEPATPEEGEP

GAGE10

31

A6NGK3
IPPTQEDTDSDGEEP

CFAP100

366

Q494V2
AETDSEPEPEPEPTA

BLOC1S3

61

Q6QNY0
PSEDLEPEVESSPEL

EIF4G1

366

Q04637
PPPEDTEEERGVTTD

LTBP3

501

Q9NS15
EPEPEEPEDVLESAK

DNAI4

431

Q5VTH9
DPEVLPTPEGPESET

KNDC1

236

Q76NI1
EDDGEEPVVFPESPL

COLGALT2

36

Q8IYK4
ESSVLEELGPEPEVP

PPP1R18

556

Q6NYC8
IEDLAKPGAEPPEED

RYR2

3641

Q92736
DEIDPDSAEEPPVSR

CLIC2

156

O15247
LDDAPLPEEETPEPT

PTCHD3

91

Q3KNS1
PEEEVTPGHEEEEPV

PARP10

626

Q53GL7
DESLLEEGEPLEPGE

FES

281

P07332
EPPEGSKEETAEAEP

GRIN3B

886

O60391
PEEFEASEVPETEPE

AK9

766

Q5TCS8
LDDPIAEVEPTDSEP

RAPGEF6

1396

Q8TEU7
DEEPESTPVPLLGSD

SPAG5

931

Q96R06
DLDLEKEPESEPDEP

SLC29A2

261

Q14542
PDETKEEEEDPPLPT

RSAD2

56

Q8WXG1
SEEDTDAVGPEPLVP

RECQL4

421

O94761
TPPPVEPEEEEDTED

EIF5B

486

O60841
FSDEVEPATPEEGEP

GAGE2B

31

Q13066
DPEEDTVESVVSPPE

INPP5D

111

Q92835
TPVPEEEEEEEEGAP

TAOK2

896

Q9UL54
DISPTPLPDSDEDEE

SETD1B

571

Q9UPS6
LTPAPVEPEEEEDEE

MYCBP2

3601

O75592
QSGTPEEPEPELEAE

NOL3

146

O60936
LPPGLQPEDEEDADE

PPP1R3G

306

B7ZBB8
DESEEEPEKELAPEP

SPDYE2B

76

A6NHP3
DSEENEPLETPAPEP

AFF1

491

P51825
LPTEPDSGFPREEEE

TJAP1

471

Q5JTD0
TEPLREGPEEEPLAE

TNRC18

1141

O15417
PDSSLEILPEEEDEG

TBC1D17

631

Q9HA65
PVKSEPTEPGDEDEE

ZFHX4

461

Q86UP3
ELPAEEPSVLGPSDE

ZSCAN10

111

Q96SZ4
EPETQSELEPEPEPE

VSIG1

351

Q86XK7
PESEPGVVVEPLSED

VSIG1

366

Q86XK7
EDSPGVAPELPEDEA

RBP3

406

P10745
PDPDSTGALVEEEDP

SERPINF1

31

P36955
DESEEEPEKELAPEP

SPDYE16

36

A6NNV3
DESEEEPEKELAPEP

SPDYE18

76

P0DV79
DESEEEPEKELAPEP

SPDYE21

76

A0A494C086
DESEEEPEKELAPEP

SPDYE2

76

Q495Y8
DDEPEKELAPEPEET

SPDYE3

61

A6NKU9
DESAEEPEKELAPEP

SPDYE5

76

A6NIY4
DESEEEPEKELAPEP

SPDYE6

76

P0CI01
EETEPPLEPEDALSD

P3H4

386

Q92791
EEEAVSEPEPEGLPE

RNF10

451

Q8N5U6
ESEIPTDPSEEPGIS

ZNF398

211

Q8TD17
AEETEADAPLPEEPS

TRPC5OS

46

A6NMA1
SCEEEELPPDPSEET

SELENON

141

Q9NZV5
DESEEEPEKELAPEP

SPDYE1

36

Q8NFV5
TPPEPEEEILGSDDE

SRPK2

41

P78362
ELGTEAPESPEEPLL

TNXB

1361

P22105
EDVDETPSPTEPGTE

TNXB

2501

P22105
PAEGEQPEVEPEESL

SCN2A

1151

Q99250
EPPLTGYPGEELEEE

PSEN2

341

P49810
EEGEDKEDSQPPTPV

DPF2

236

Q92785
EEEDVEAAPEPGPSE

SOCS7

11

O14512
TTEEEEEQPGKAPDP

ZSCAN18

321

Q8TBC5
DESEEEPEKELAPEP

nan

36

A6NJR5
DDPVPLPVSGDKEED

VIRMA

196

Q69YN4
EEEPTGWEEPSPESI

TNRC6A

981

Q8NDV7
DDDPPTPEEDSETQP

TERF2IP

281

Q9NYB0
DNAELGPEDPEEELP

THEG

51

Q9P2T0
PEEVAGEEFPETLDP

THEG

66

Q9P2T0
APEPDISEEELSPEV

ZNF184

111

Q99676
PEEEEEEWGDVPLSP

ZFTA

521

C9JLR9
SEHEGDTPELEAEPP

ZNF641

191

Q96N77