Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	2.19e-05	2	94	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	2.19e-05	2	94	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	2.19e-05	2	94	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	2.19e-05	2	94	2	GO:0004354
GeneOntologyMolecularFunction	tRNA 2'-O-methyltransferase activity	FTSJ1 TRMT13	2.19e-05	2	94	2	GO:0106050
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHB3 EPHA6 EPHA4	4.41e-05	15	94	3	GO:0005005
GeneOntologyMolecularFunction	ephrin receptor activity	EPHB3 EPHA6 EPHA4	9.27e-05	19	94	3	GO:0005003
GeneOntologyMolecularFunction	kinase activity	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 HKDC1 MAGI3 MAST2 GK5 STK35 EPHA4	2.43e-04	764	94	12	GO:0016301
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	4.53e-04	7	94	2	GO:0070728
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 HKDC1 MAST2 GK5 STK35 EPHA4	4.96e-04	709	94	11	GO:0016773
GeneOntologyMolecularFunction	tRNA methyltransferase activity	FTSJ1 TRMT13 TRMT2B	5.44e-04	34	94	3	GO:0008175
GeneOntologyMolecularFunction	RNA 2'-O-methyltransferase activity	FTSJ1 TRMT13	7.73e-04	9	94	2	GO:0062105
GeneOntologyMolecularFunction	calcium ion binding	STAB2 CELSR2 DSC3 PLCH2 FSTL5 C1R DLK1 LTBP3 F2 FER1L5 LRP1B	7.82e-04	749	94	11	GO:0005509
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 HKDC1 MAGI3 MAST2 GK5 STK35 EPHA4	1.48e-03	938	94	12	GO:0016772
GeneOntologyMolecularFunction	RNA 7-methylguanosine cap binding	GEMIN5 CYFIP2	1.92e-03	14	94	2	GO:0000340
GeneOntologyMolecularFunction	protein kinase activity	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 MAST2 STK35 EPHA4	2.07e-03	600	94	9	GO:0004672
GeneOntologyBiologicalProcess	regulation of insulin secretion	OSBP ABCA12 GLUD1 GLUD2 SYBU F2 FKBP1B	9.04e-05	231	94	7	GO:0050796
GeneOntologyBiologicalProcess	oocyte growth	KMT2D FOXL2	1.23e-04	4	94	2	GO:0001555
GeneOntologyBiologicalProcess	glutamate biosynthetic process	GLUD1 GLUD2	2.04e-04	5	94	2	GO:0006537
GeneOntologyBiologicalProcess	regulation of hormone secretion	OSBP FOXL2 ABCA12 GLUD1 GLUD2 SYBU F2 FKBP1B	2.19e-04	355	94	8	GO:0046883
GeneOntologyBiologicalProcess	peptide transport	OSBP SLC15A2 ABCA12 GLUD1 GLUD2 SYBU F2 FKBP1B	2.19e-04	355	94	8	GO:0015833
GeneOntologyBiologicalProcess	positive regulation of insulin secretion	OSBP GLUD1 GLUD2 SYBU F2	2.23e-04	120	94	5	GO:0032024
GeneOntologyBiologicalProcess	insulin secretion	OSBP ABCA12 GLUD1 GLUD2 SYBU F2 FKBP1B	2.59e-04	274	94	7	GO:0030073
GeneOntologyBiologicalProcess	regulation of peptide hormone secretion	OSBP ABCA12 GLUD1 GLUD2 SYBU F2 FKBP1B	2.76e-04	277	94	7	GO:0090276
GeneOntologyBiologicalProcess	neuron projection fasciculation	EPHB3 FEZF2 EPHA4	2.76e-04	28	94	3	GO:0106030
GeneOntologyBiologicalProcess	axonal fasciculation	EPHB3 FEZF2 EPHA4	2.76e-04	28	94	3	GO:0007413
GeneOntologyBiologicalProcess	response to aluminum ion	GLUD1 GLUD2	3.05e-04	6	94	2	GO:0010044
GeneOntologyBiologicalProcess	regulation of peptide transport	OSBP ABCA12 GLUD1 GLUD2 SYBU F2 FKBP1B	3.08e-04	282	94	7	GO:0090087
GeneOntologyBiologicalProcess	regulation of peptide secretion	OSBP ABCA12 GLUD1 GLUD2 SYBU F2 FKBP1B	3.08e-04	282	94	7	GO:0002791
GeneOntologyBiologicalProcess	axon guidance	EPHB3 SEMA4D EPHA6 FEZF2 LAMA2 CYFIP2 EPHA4	3.28e-04	285	94	7	GO:0007411
GeneOntologyBiologicalProcess	neuron projection guidance	EPHB3 SEMA4D EPHA6 FEZF2 LAMA2 CYFIP2 EPHA4	3.35e-04	286	94	7	GO:0097485
GeneOntologyBiologicalProcess	positive regulation of hormone secretion	OSBP FOXL2 GLUD1 GLUD2 SYBU F2	3.53e-04	205	94	6	GO:0046887
Domain	EGF	STAB2 CELSR2 ATRNL1 LAMA2 C1R DLK1 LTBP3 TECTA LRP1B ITGB5	2.66e-07	235	93	10	SM00181
Domain	EGF-like_dom	STAB2 CELSR2 ADAM18 ATRNL1 LAMA2 C1R DLK1 LTBP3 TECTA LRP1B	4.54e-07	249	93	10	IPR000742
Domain	EGF_extracell	STAB2 ADAM18 ATRNL1 DLK1 LRP1B ITGB5	5.22e-07	60	93	6	IPR013111
Domain	EGF_2	STAB2 ADAM18 ATRNL1 DLK1 LRP1B ITGB5	5.22e-07	60	93	6	PF07974
Domain	EGF_1	STAB2 CELSR2 ADAM18 ATRNL1 LAMA2 C1R DLK1 LTBP3 LRP1B ITGB5	5.64e-07	255	93	10	PS00022
Domain	EGF-like_CS	STAB2 CELSR2 ADAM18 ATRNL1 LAMA2 C1R DLK1 LTBP3 LRP1B ITGB5	6.98e-07	261	93	10	IPR013032
Domain	EGF_2	STAB2 CELSR2 ADAM18 ATRNL1 LAMA2 C1R DLK1 LTBP3 LRP1B ITGB5	8.01e-07	265	93	10	PS01186
Domain	EGF_LAM_2	STAB2 CELSR2 ATRNL1 LAMA2	1.43e-05	30	93	4	PS50027
Domain	EGF_LAM_1	STAB2 CELSR2 ATRNL1 LAMA2	1.43e-05	30	93	4	PS01248
Domain	EGF_3	STAB2 CELSR2 ADAM18 ATRNL1 C1R DLK1 LTBP3 LRP1B	2.26e-05	235	93	8	PS50026
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	2.45e-05	2	93	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	2.45e-05	2	93	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	2.45e-05	2	93	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	2.45e-05	2	93	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	2.45e-05	2	93	2	PF00208
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	2.45e-05	2	93	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	2.45e-05	2	93	2	PS00074
Domain	ELFV_dehydrog	GLUD1 GLUD2	2.45e-05	2	93	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	2.45e-05	2	93	2	IPR033524
Domain	EGF_Lam	STAB2 CELSR2 ATRNL1 LAMA2	2.68e-05	35	93	4	SM00180
Domain	EGF_CA	STAB2 CELSR2 C1R DLK1 LTBP3 LRP1B	3.29e-05	122	93	6	SM00179
Domain	EGF-like_Ca-bd_dom	STAB2 CELSR2 C1R DLK1 LTBP3 LRP1B	3.61e-05	124	93	6	IPR001881
Domain	Laminin_EGF	STAB2 CELSR2 ATRNL1 LAMA2	3.74e-05	38	93	4	IPR002049
Domain	EGF	STAB2 CELSR2 DLK1 TECTA LRP1B ITGB5	3.95e-05	126	93	6	PF00008
Domain	RECEPTOR_TYR_KIN_V_2	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	PS00790
Domain	Tyr_kinase_rcpt_V_CS	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	IPR001426
Domain	EphA2_TM	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	PF14575
Domain	Ephrin_rcpt_lig-bd_dom	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	IPR001090
Domain	Eph_TM	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	IPR027936
Domain	EPH_lbd	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	SM00615
Domain	Ephrin_lbd	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	PF01404
Domain	Tyr_kinase_ephrin_rcpt	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	IPR016257
Domain	EPH_LBD	EPHB3 EPHA6 EPHA4	4.18e-05	14	93	3	PS51550
Domain	CK1gamma_C	CSNK1G3 CSNK1G1	7.33e-05	3	93	2	PF12605
Domain	Casein_kinase-1_gamma_C	CSNK1G3 CSNK1G1	7.33e-05	3	93	2	IPR022247
Domain	CUB	ATRNL1 C1R CDCP2 CSMD1	1.03e-04	49	93	4	PF00431
Domain	CUB	ATRNL1 C1R CDCP2 CSMD1	1.11e-04	50	93	4	SM00042
Domain	Growth_fac_rcpt_	EPHB3 STAB2 CELSR2 EPHA6 LTBP3 LRP1B	1.29e-04	156	93	6	IPR009030
Domain	-	ATRNL1 C1R CDCP2 CSMD1	1.30e-04	52	93	4	2.60.120.290
Domain	CUB	ATRNL1 C1R CDCP2 CSMD1	1.40e-04	53	93	4	PS01180
Domain	ASX_HYDROXYL	CELSR2 C1R DLK1 LTBP3 LRP1B	1.42e-04	100	93	5	PS00010
Domain	CUB_dom	ATRNL1 C1R CDCP2 CSMD1	1.86e-04	57	93	4	IPR000859
Domain	EGF-type_Asp/Asn_hydroxyl_site	CELSR2 C1R DLK1 LTBP3 LRP1B	1.87e-04	106	93	5	IPR000152
Domain	FYrich_C	KMT2D TBRG1	2.43e-04	5	93	2	IPR003889
Domain	FYrich_N	KMT2D TBRG1	2.43e-04	5	93	2	IPR003888
Domain	FYRC	KMT2D TBRG1	2.43e-04	5	93	2	SM00542
Domain	FYRN	KMT2D TBRG1	2.43e-04	5	93	2	SM00541
Domain	FYRN	KMT2D TBRG1	2.43e-04	5	93	2	PF05964
Domain	FYRC	KMT2D TBRG1	2.43e-04	5	93	2	PF05965
Domain	FYRC	KMT2D TBRG1	2.43e-04	5	93	2	PS51543
Domain	FYRN	KMT2D TBRG1	2.43e-04	5	93	2	PS51542
Domain	Ephrin_rec_like	EPHB3 EPHA6 EPHA4	2.54e-04	25	93	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB3 EPHA6 EPHA4	2.54e-04	25	93	3	IPR011641
Domain	PROTEIN_KINASE_ATP	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 MAST2 STK35 EPHA4	4.69e-04	459	93	9	PS00107
Domain	-	EPHB3 EPHA6 LAMA2 EPHA4	4.82e-04	73	93	4	2.60.120.260
Domain	Protein_kinase_ATP_BS	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 STK35 EPHA4	6.06e-04	379	93	8	IPR017441
Domain	Prot_kinase_dom	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 MAST2 STK35 EPHA4	7.37e-04	489	93	9	IPR000719
Domain	PROTEIN_KINASE_DOM	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 MAST2 STK35 EPHA4	7.81e-04	493	93	9	PS50011
Domain	Galactose-bd-like	EPHB3 EPHA6 LAMA2 EPHA4	1.25e-03	94	93	4	IPR008979
Domain	PSI	SEMA4D ATRNL1 ITGB5	1.37e-03	44	93	3	IPR016201
Domain	Kinase-like_dom	EPHB3 EPHA6 CSNK1G3 GRK4 CSNK1G1 BUB1 MAST2 STK35 EPHA4	1.51e-03	542	93	9	IPR011009
Domain	PSI	SEMA4D ATRNL1 ITGB5	1.55e-03	46	93	3	SM00423
Domain	S_TKc	CSNK1G3 GRK4 CSNK1G1 BUB1 MAST2 STK35 EPHA4	2.10e-03	359	93	7	SM00220
Domain	C2	RPGRIP1L PLCH2 WWP1 FER1L5	4.17e-03	131	93	4	PF00168
Domain	C2	RPGRIP1L PLCH2 WWP1 FER1L5	4.89e-03	137	93	4	SM00239
Pubmed	Proximity of the CTLA-1 serine esterase and Tcr alpha loci in mouse and man.	GZMH GLUD1 GLUD2	1.97e-07	5	95	3	3182016
Pubmed	Glutamate dehydrogenase in cerebellar mutant mice: gene localization and enzyme activity in different tissues.	GZMH GLUD1 GLUD2	1.64e-06	9	95	3	2293612
Pubmed	Insufficient CD100 shedding contributes to suppression of CD8+ T-cell activity in non-small cell lung cancer.	SEMA4D MMP14	7.38e-06	2	95	2	32149403
Pubmed	Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	7.38e-06	2	95	2	15750346
Pubmed	Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.	GLUD1 GLUD2	7.38e-06	2	95	2	1711373
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	7.38e-06	2	95	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	7.38e-06	2	95	2	28621566
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	7.38e-06	2	95	2	32078638
Pubmed	Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.	GLUD1 GLUD2	7.38e-06	2	95	2	20529287
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	7.38e-06	2	95	2	23595828
Pubmed	Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).	GLUD1 GLUD2	7.38e-06	2	95	2	25124006
Pubmed	Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.	GLUD1 GLUD2	7.38e-06	2	95	2	23673664
Pubmed	MT1-MMP controls tumor-induced angiogenesis through the release of semaphorin 4D.	SEMA4D MMP14	7.38e-06	2	95	2	17204469
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	7.38e-06	2	95	2	21621574
Pubmed	Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.	GLUD1 GLUD2	7.38e-06	2	95	2	39052831
Pubmed	Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.	GLUD1 GLUD2	7.38e-06	2	95	2	24442550
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	7.38e-06	2	95	2	28911206
Pubmed	The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.	GLUD1 GLUD2	7.38e-06	2	95	2	27137930
Pubmed	GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.	GLUD1 GLUD2	7.38e-06	2	95	2	26440896
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	7.38e-06	2	95	2	22875990
Pubmed	Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.	GLUD1 GLUD2	7.38e-06	2	95	2	12742085
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	7.38e-06	2	95	2	15578726
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	7.38e-06	2	95	2	15044002
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	7.38e-06	2	95	2	22138648
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	7.38e-06	2	95	2	34220417
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	7.38e-06	2	95	2	26241911
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	7.38e-06	2	95	2	21446915
Pubmed	Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.	GLUD1 GLUD2	7.38e-06	2	95	2	18688271
Pubmed	The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.	GLUD1 GLUD2	7.38e-06	2	95	2	22658952
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	7.38e-06	2	95	2	38060673
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	7.38e-06	2	95	2	24593767
Pubmed	Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.	GLUD1 GLUD2	7.38e-06	2	95	2	38124277
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	7.38e-06	2	95	2	37154294
Pubmed	Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.	GLUD1 GLUD2	7.38e-06	2	95	2	19015267
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	7.38e-06	2	95	2	22924626
Pubmed	Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.	GLUD1 GLUD2	7.38e-06	2	95	2	19448744
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	7.38e-06	2	95	2	11032875
Pubmed	Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.	GLUD1 GLUD2	7.38e-06	2	95	2	11950837
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	7.38e-06	2	95	2	29943084
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	7.38e-06	2	95	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	7.38e-06	2	95	2	15378063
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	7.38e-06	2	95	2	27422263
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB3 EPHA6 EPHA4	1.31e-05	17	95	3	12217323
Pubmed	Chromosomal localization of the mouse genes coding for alpha 2, alpha 3, alpha 4 and beta 2 subunits of neuronal nicotinic acetylcholine receptor.	GZMH GLUD1 GLUD2	1.56e-05	18	95	3	2338144
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHB3 EPHA6 EPHA4	1.85e-05	19	95	3	12684176
Pubmed	Common fragile sites (CFS) and extremely large CFS genes are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.	CSMD1 LRP1B	2.21e-05	3	95	2	27636103
Pubmed	Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.	GLUD1 GLUD2	2.21e-05	3	95	2	29784783
Pubmed	The structure of apo human glutamate dehydrogenase details subunit communication and allostery.	GLUD1 GLUD2	2.21e-05	3	95	2	12054821
Pubmed	Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.	GLUD1 GLUD2	2.21e-05	3	95	2	31704028
Pubmed	Cross talk between engulfment receptors stabilin-2 and integrin αvβ5 orchestrates engulfment of phosphatidylserine-exposed erythrocytes.	STAB2 ITGB5	2.21e-05	3	95	2	22566688
Pubmed	The effects of Eph-ephrin mutations on pre-pulse inhibition in mice.	EPHB3 EPHA4	2.21e-05	3	95	2	24949848
Pubmed	Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase.	GLUD1 GLUD2	2.21e-05	3	95	2	29229616
Pubmed	Liver Glutamate Dehydrogenase Controls Whole-Body Energy Partitioning Through Amino Acid-Derived Gluconeogenesis and Ammonia Homeostasis.	GLUD1 GLUD2	2.21e-05	3	95	2	30002133
Pubmed	Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens.	GLUD1 GLUD2	2.21e-05	3	95	2	30315226
Pubmed	Ephrin-B3, a ligand for the receptor EphB3, expressed at the midline of the developing neural tube.	EPHB3 EPHA4	2.21e-05	3	95	2	9484836
Pubmed	Isolation of a human brain cDNA for glutamate dehydrogenase.	GLUD1 GLUD2	2.21e-05	3	95	2	3585334
Pubmed	Collagen I and thrombin activate MMP-2 by MMP-14-dependent and -independent pathways: implications for airway smooth muscle migration.	F2 MMP14	2.21e-05	3	95	2	17189319
Pubmed	GOT1 regulates CD8+ effector and memory T cell generation.	GLUD1 GLUD2	2.21e-05	3	95	2	36640309
Pubmed	Nephronophthisis.	RPGRIP1L INVS	2.21e-05	3	95	2	19066617
Pubmed	Screening for new inhibitors of the human Mitochondrial Pyruvate Carrier and their effects on hepatic glucose production and diabetes.	GLUD1 GLUD2	2.21e-05	3	95	2	37871770
Pubmed	Casein kinase-1γ1 and 3 stimulate tumor necrosis factor-induced necroptosis through RIPK3.	CSNK1G3 CSNK1G1	2.21e-05	3	95	2	31801942
Pubmed	Deletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning.	GLUD1 GLUD2	2.21e-05	3	95	2	23560106
Pubmed	Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.	GLUD1 GLUD2	2.21e-05	3	95	2	20670938
Pubmed	Identification of disulfide bond formation between MitoNEET and glutamate dehydrogenase 1.	GLUD1 GLUD2	2.21e-05	3	95	2	24295216
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHB3 EPHA6 EPHA4	2.53e-05	21	95	3	9267020
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHB3 EPHA6 EPHA4	2.53e-05	21	95	3	10495276
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHB3 EPHA6 EPHA4	2.53e-05	21	95	3	20112066
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHB3 EPHA6 EPHA4	2.53e-05	21	95	3	11128993
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHB3 EPHA6 EPHA4	2.53e-05	21	95	3	10730216
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MDN1 DAZAP1 XPO5 CLIC1 STARD9 DDX52 GLUD1 GART GEMIN5 RPS16 BOD1L1 F2 MAST2 CYFIP2	3.23e-05	1425	95	14	30948266
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHB3 EPHA6 EPHA4	3.36e-05	23	95	3	19542359
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	TNRC18 MDN1 STARD9 DDX52 GLUD1 GLUD2 SLC44A2 HKDC1 MAGI3 NLE1 BOD1L1 SLC25A31 CYFIP2 EPHA4	3.68e-05	1442	95	14	35575683
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	EPHB3 EPHA6 EPHA4	3.83e-05	24	95	3	16446123
Pubmed	Isolation and mapping of novel mouse brain cDNA clones containing trinucleotide repeats, and demonstration of novel alleles in recombinant inbred strains.	MDN1 GLUD1 GLUD2	4.35e-05	25	95	3	8858346
Pubmed	Enriched expression of GluD1 in higher brain regions and its involvement in parallel fiber-interneuron synapse formation in the cerebellum.	GLUD1 GLUD2	4.41e-05	4	95	2	24872547
Pubmed	Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity.	GLUD1 GLUD2	4.41e-05	4	95	2	25721396
Pubmed	Eph receptor interclass cooperation is required for the regulation of cell proliferation.	EPHB3 EPHA4	4.41e-05	4	95	2	27565439
Pubmed	The involvement of collagen triple helix repeat containing 1 in muscular dystrophies.	LAMA2 CTHRC1	4.41e-05	4	95	2	23274062
Pubmed	Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null mice.	COL4A2 LAMA2	4.41e-05	4	95	2	9175728
Pubmed	Beta1 integrins control the formation of cell chains in the adult rostral migratory stream.	LAMA2 ITGB5	4.41e-05	4	95	2	17344408
Pubmed	Rac-GAP alpha-chimerin regulates motor-circuit formation as a key mediator of EphrinB3/EphA4 forward signaling.	EPHB3 EPHA4	4.41e-05	4	95	2	17719550
Pubmed	The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.	GLUD1 GLUD2	4.41e-05	4	95	2	23663782
Pubmed	A splice variant of human ephrin-A4 encodes a soluble molecule that is secreted by activated human B lymphocytes.	EPHA6 EPHA4	4.41e-05	4	95	2	10607706
Pubmed	Histiocytic sarcoma: New insights into FNA cytomorphology and molecular characteristics.	KMT2D CD163	4.41e-05	4	95	2	28805986
Pubmed	GLUD1 determines murine muscle stem cell fate by controlling mitochondrial glutamate levels.	GLUD1 GLUD2	4.41e-05	4	95	2	39121856
Pubmed	A restriction fragment length polymorphism at murine Glud locus co-segregates with Rib-1, Es-10, and Tcra on chromosome 14.	GLUD1 GLUD2	4.41e-05	4	95	2	2566156
Pubmed	Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants.	COL4A2 RPGRIP1L	4.41e-05	4	95	2	36438572
Pubmed	Graded and discontinuous EphA-ephrinB expression patterns in the developing auditory brainstem.	EPHB3 EPHA4	4.41e-05	4	95	2	26906676
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TNRC18 KMT2D MDN1 CELSR2 WWP1 GEMIN5 NLE1 LTBP3 MMP14 MAST2 ITGB5 TOP3A	4.82e-05	1105	95	12	35748872
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SEMA4D ZNF133 TNRC18 DAZAP1 EPHA6 WWP1 MAGI3 BOD1L1 TRMT13 CSMD1 TECTA ITGB5 INVS EXOC4	5.20e-05	1489	95	14	28611215
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	EPHB3 SEMA4D CELSR2 WWP1 GART CYFIP2 EPHA4	5.87e-05	358	95	7	32460013
Pubmed	The Crystal Structure of the Ubiquitin-like Domain of Ribosome Assembly Factor Ytm1 and Characterization of Its Interaction with the AAA-ATPase Midasin.	MDN1 NLE1	7.34e-05	5	95	2	26601951
Pubmed	Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred.	EPHA6 EPHA4	7.34e-05	5	95	2	12084815
Pubmed	Chromosomal mapping of glutamate dehydrogenase gene sequences to mouse chromosomes 7 and 14.	GLUD1 GLUD2	7.34e-05	5	95	2	2045113
Pubmed	EphB2 and EphA4 receptors regulate formation of the principal inter-hemispheric tracts of the mammalian forebrain.	EPHB3 EPHA4	7.34e-05	5	95	2	19289155
Pubmed	Chromosomal assignment of 11 loci in the rat by mouse-rat somatic hybrids and linkage.	GLUD1 GLUD2	7.34e-05	5	95	2	7873882
Pubmed	SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.	GLUD1 GLUD2	7.34e-05	5	95	2	16959573
Pubmed	Eph receptors are involved in the activity-dependent synaptic wiring in the mouse cerebellar cortex.	EPHB3 EPHA4	7.34e-05	5	95	2	21559471
Pubmed	Role for casein kinase 1 in the phosphorylation of Claspin on critical residues necessary for the activation of Chk1.	CSNK1G3 CSNK1G1	7.34e-05	5	95	2	21680713
Pubmed	Genomic organization and chromosomal localization of the mouse synexin gene.	GLUD1 GLUD2	7.34e-05	5	95	2	8053909
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB3 EPHA6 EPHA4	1.64e-05	14	66	3	1095
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNRC18 PEG3 CSMD1 F2 STK35 EPHA4	1.10e-06	157	95	6	1f21d78a467fe22c5ab75d0917b840c1ac93f32c
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CELF5 CELSR2 DSC3 ABCA12 WFDC5 SYBU	1.19e-06	159	95	6	22427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PEG3 GLUD2 KCTD4 CTHRC1 DLK1 ITGB5	2.21e-06	177	95	6	b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 LAMA2 C1R DLK1 MMP14 LRP1B	2.95e-06	186	95	6	7582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCell	E15.5-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SLC15A2 PEG3 CTHRC1 ADAMTS18 DLK1 EPHA4	3.04e-06	187	95	6	1288fcd0124c70711521f3ac83554e9acdd37cb2
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A2 DSC3 PEG3 CTHRC1 DLK1 CYFIP2	3.23e-06	189	95	6	d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	DSC3 ATRNL1 PEG3 LAMA2 C1R DLK1	3.65e-06	193	95	6	09de51f8ac509e03d480ed3dc9dfe7e7defc59cb
ToppCell	(3)_Chondrocytes-(30)_Chondro\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	COL4A2 STAB2 DSC3 LAMA2 SLC40A1 EPHA4	3.87e-06	195	95	6	f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A2 PEG3 LAMA2 CTHRC1 DLK1 LTBP3	4.23e-06	198	95	6	b086af292a508a156266c2d899ba1caf820bf61c
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	LAMA2 CTHRC1 C1R MMP14 SLC40A1 ITGB5	4.48e-06	200	95	6	e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPHA6 SLC15A2 FEZF2 GLUD1 LRP1B CYFIP2	4.48e-06	200	95	6	07d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPHA6 SLC15A2 FEZF2 GLUD1 LRP1B CYFIP2	4.48e-06	200	95	6	d0812817ef99608994193787a62d39adeb2070ca
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAMA2 CTHRC1 C1R MMP14 SLC40A1 ITGB5	4.48e-06	200	95	6	2cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	LAMA2 CTHRC1 C1R MMP14 SLC40A1 ITGB5	4.48e-06	200	95	6	8cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPHA6 SLC15A2 FEZF2 GLUD1 LRP1B CYFIP2	4.48e-06	200	95	6	cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 ATRNL1 CASP9 FTSJ1 SLC40A1	9.80e-06	133	95	5	f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 ATRNL1 CASP9 FTSJ1 SLC40A1	9.80e-06	133	95	5	292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPHA6 ABCA12 ATRNL1 FSTL5 LRP1B	1.21e-05	139	95	5	a1945b07f177cde40e7eea03a19236ce76165857
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets-Platelets\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIMS1 TOPAZ1 DLK1 FKBP1B ITGB5	1.87e-05	152	95	5	aff7d1127ef72be489477611c4decc53cc7632e3
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIMS1 TOPAZ1 DLK1 FKBP1B ITGB5	1.87e-05	152	95	5	0a99c91165e4d82fb8825fbdf3071c9a5445669d
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	MDN1 FSTL5 GLUD1 LRP1B CSDC2	2.46e-05	161	95	5	347edb0de10850b7d16c40945751033289289c9b
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHA6 BUB1 DLK1 TECTA LRP1B	2.54e-05	162	95	5	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-6\|TCGA-Bladder / Sample_Type by Project: Shred V9	EPHB3 CELSR2 DSC3 ABCA12 WFDC5	3.29e-05	171	95	5	0e78389f8f3d54570a6deb3dd307b865b46307e9
ToppCell	18-Airway-Epithelial-Submucosal_gland_basal\|Airway / Age, Tissue, Lineage and Cell class	EPHB3 COL4A2 DSC3 PLCH2 ADAMTS18	4.31e-05	181	95	5	33938e6521712058312879f84f4ae381c2bfc379
ToppCell	AT1-AT2_cells-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	COL4A2 MAGI3 SYBU FKBP1B SLC40A1	4.31e-05	181	95	5	ca23ce4f2c7b684d8ddd0e8619b3b696023d75e3
ToppCell	facs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WWP1 FSTL5 CTHRC1 F2 EPHA4	4.31e-05	181	95	5	4ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PEG3 LAMA2 CTHRC1 DLK1 ITGB5	4.66e-05	184	95	5	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	PTPN12 KCTD4 TECTA MMP14 CD163	4.78e-05	185	95	5	7bff05d8d34616adbaa0ea0b69eb30aa906bb9f8
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	KMT2D DDHD1 MAST2 INVS EXOC4	4.78e-05	185	95	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PEG3 LAMA2 CTHRC1 DLK1 ITGB5	4.91e-05	186	95	5	c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Proliferative_AT2_Progenitor\|E16.5-samps / Age Group, Lineage, Cell class and subclass	SLC15A2 CTHRC1 ADAMTS18 DLK1 EPHA4	5.03e-05	187	95	5	e986901f5a1e09cbc9ba37e3c62845ff90ceda95
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	LIMS1 BCO2 LAMA2 ADAMTS18 MAGI3	5.03e-05	187	95	5	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	Fibroblast-C\|World / shred on cell class and cell subclass (v4)	PEG3 LAMA2 CTHRC1 DLK1 MMP14	5.29e-05	189	95	5	58e0400fbab5a0755504275aef5cf7986149abab
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PEG3 LAMA2 CTHRC1 DLK1 MMP14	5.43e-05	190	95	5	947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PEG3 LAMA2 CTHRC1 DLK1 MMP14	5.56e-05	191	95	5	db4943dd19207663fb9e27f8940fa4b06a933625
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMA2 CTHRC1 C1R MMP14 CSDC2	5.56e-05	191	95	5	0fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PEG3 LAMA2 CTHRC1 DLK1 MMP14	5.70e-05	192	95	5	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	EPHB3 CTHRC1 ADAMTS18 DLK1 EPHA4	5.70e-05	192	95	5	d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCell	COVID-19-lung-Secretory\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DSC3 SLC15A2 PLCH2 MAGI3 SYBU	5.70e-05	192	95	5	59261098ccb52306f837f632ebaea45b90ad30fe
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PEG3 LAMA2 CTHRC1 DLK1 MMP14	5.70e-05	192	95	5	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL4A2 LAMA2 CTHRC1 C1R MMP14	5.84e-05	193	95	5	b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PEG3 LAMA2 CTHRC1 DLK1 MMP14	5.84e-05	193	95	5	051f61156b0e2e95292b2d8377faf3190b50f264
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DSC3 ATRNL1 KCTD4 C1R SLC40A1	5.99e-05	194	95	5	421344cc4b601d9745fa72d0af3124dab11d1d27
ToppCell	367C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	WWP1 MMP14 SLC40A1 ITGB5 CD163	6.14e-05	195	95	5	4008fa86b5166087a4b20f89ae07e1dfc87c855d
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PEG3 CTHRC1 ADAMTS18 DLK1 MMP14	6.14e-05	195	95	5	febe746099964b9ea9e75f2efc72c962c01f0421
ToppCell	(3)_MNP-(3)_Macrophage_MARCOneg\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	WWP1 MMP14 SLC40A1 ITGB5 CD163	6.14e-05	195	95	5	e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCell	E12.5-Mesenchymal-mesenchymal_fibroblast\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATXN7L3B PEG3 CTHRC1 RPS16 DLK1	6.14e-05	195	95	5	def0a3fb36eec6fbb08e1323baf2b22b28bf751a
ToppCell	(1)_T_cells-(1)_T_CD8_CTL\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	PTPN12 CLIC1 GZMH GK5 FKBP1B	6.29e-05	196	95	5	ad9b0651cb2a15b750e453b2dcf782bca08b4fe7
ToppCell	Bronchial-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CELSR2 EPHA6 CCDC73 A2ML1 RPS16	6.29e-05	196	95	5	efeb272bc9e37e60d15d056b7574991c5c7501bc
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC3 PEG3 CTHRC1 DLK1 SLC40A1	6.44e-05	197	95	5	7c275a2ac24a9a4f83fceda93a067e754837102f
ToppCell	(3)_Chondrocytes-(30)_Chondro\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	DSC3 PEG3 KCTD4 SLC40A1 EPHA4	6.44e-05	197	95	5	a07ab2564ca7d577fd47f444dd7b0c25556e9fc4
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC3 PEG3 C1R DLK1 SLC40A1	6.44e-05	197	95	5	6b6440f1baad5680cf9e13ca3ab72a2c65523d59
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL4A2 PEG3 LAMA2 DLK1 ZIC1	6.60e-05	198	95	5	55e583321f60c95898d93cd0d2615c6692db52ec
ToppCell	Non-neuronal-Postmitotic-Mural-Mural\|World / Primary Cells by Cluster	COL4A2 CLIC1 LAMA2 SLC40A1 ZIC1	6.60e-05	198	95	5	9fc1035ea447a4551a66944c869c4671e17cec61
ToppCell	Non-neuronal-Postmitotic-Mural\|World / Primary Cells by Cluster	COL4A2 CLIC1 LAMA2 SLC40A1 ZIC1	6.60e-05	198	95	5	dd38840a96171f58da243daa22b013e15a81db4a
ToppCell	Non-neuronal-Postmitotic-Mural-Mural-18\|World / Primary Cells by Cluster	COL4A2 CLIC1 LAMA2 SLC40A1 ZIC1	6.60e-05	198	95	5	21efb7bcd24f24d20791b34e75d6f9d46a129481
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	WWP1 MMP14 SLC40A1 ITGB5 CD163	6.75e-05	199	95	5	2649afa3ccda78e9d1df26127b66cbfa0c6cd01d
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL4A2 PEG3 LAMA2 DLK1 ZIC1	6.75e-05	199	95	5	e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCell	metastatic_Brain-Fibroblasts-FB-like_cells\|metastatic_Brain / Location, Cell class and cell subclass	COL4A2 LAMA2 CTHRC1 C1R ZIC1	6.75e-05	199	95	5	12133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell	metastatic_Brain-Fibroblasts\|metastatic_Brain / Location, Cell class and cell subclass	COL4A2 LAMA2 CTHRC1 C1R ZIC1	6.75e-05	199	95	5	63eb2106bb6e2e33d020628583536c8d96662c84
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DSC3 PEG3 LAMA2 CTHRC1 DLK1	6.75e-05	199	95	5	83383d9ae4f501754fd3da0215ce6f0e3c70562c
ToppCell	10x3'2.3-week_17-19-Mesenchymal_myocytic\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL4A2 PEG3 LAMA2 DLK1 ZIC1	6.75e-05	199	95	5	801887db51ac5dc5b068808ff75e3a46643398e9
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Macroglial-Astrocyte\|5w / Sample Type, Dataset, Time_group, and Cell type.	FEZF2 CLIC1 RPS16 DLK1 ZIC1	6.92e-05	200	95	5	b64f3f1484de49777efb9b998577ff6bbb6e6861
ToppCell	COVID-19-Fibroblasts-Pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	LAMA2 CTHRC1 RPS16 C1R MMP14	6.92e-05	200	95	5	73e01b7bc43320a991c67a4fd0c04708f893c7ea
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CELSR2 XPO5 NLE1 SYBU FAM47E	6.92e-05	200	95	5	68b0f987c4fb8078675475f4f1e71302f832ef69
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CELSR2 XPO5 NLE1 SYBU FAM47E	6.92e-05	200	95	5	1b527bebbca1ef8c52449e40beb9358e37494e04
ToppCell	COVID-19-lung-Myofibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CTHRC1 RPS16 C1R MMP14 SLC40A1	6.92e-05	200	95	5	ccb0fea3fab1227d8c6da7281c1a852c3db42ee9
ToppCell	Sigmoid-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	BUB1 MMP14 SLC40A1 ITGB5 CD163	6.92e-05	200	95	5	372fe9018481a4e9ac6ab3af43705a48238c4376
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-BMP_responsible_cell\|5w / Sample Type, Dataset, Time_group, and Cell type.	EPHA6 FEZF2 CLIC1 DLK1 ZIC1	6.92e-05	200	95	5	ce8a3a8367bafdfabc7c2f96b003aa99526a54e4
ToppCell	COVID-19-lung-Myofibroblast\|lung / Disease (COVID-19 only), tissue and cell type	CTHRC1 RPS16 C1R MMP14 SLC40A1	6.92e-05	200	95	5	3179210cbfa99834bed4db182ce6095a086d64a9
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-CPNs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	CELF5 SYBU FKBP1B EPHA4 EXOC4	6.92e-05	200	95	5	71cbefbef4ae5bbb5f6e419914f4b3b3b5a5f9e3
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC44A2 SLC40A1 CD163 INVS	1.58e-04	127	95	4	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RPGRIP1L HKDC1 GEMIN5 CSMD1	1.68e-04	129	95	4	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9\|TCGA-Brain / Sample_Type by Project: Shred V9	SLC15A2 FSTL5 GLUD1 MAGI3	1.94e-04	134	95	4	2647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l28\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZCWPW1 FBXL18 KCTD4 CTHRC1	2.49e-04	143	95	4	b4ed3855652fdf32f97cb7c18cab4f4f4c24d5c7
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EPHB3 KMT2D ATRNL1 TECTA	2.49e-04	143	95	4	92ddc3e3f6ba78dd9daeb272c12503ec2650a874
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA6 BUB1 TECTA LRP1B	2.62e-04	145	95	4	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EPHA6 ATRNL1 FSTL5 LRP1B	2.84e-04	148	95	4	d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TOPAZ1 ATRNL1 FSTL5 LRP1B	2.99e-04	150	95	4	0205318a870e091add66ee4305747dda9f51510d
ToppCell	normal_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	CELSR2 WWP1 SLC40A1 CD163	3.22e-04	153	95	4	5424494ea1f09542799045a875cc3eac13de5079
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OSBP SLC15A2 SYBU SLC40A1	3.64e-04	158	95	4	12661763d1c309106801cb710c04cd2b62d16cba
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OSBP SLC15A2 SYBU SLC40A1	3.64e-04	158	95	4	e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCell	facs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OSBP SLC15A2 SYBU SLC40A1	3.64e-04	158	95	4	0792c39e6fc0745095af7812de2d50949540d60f
ToppCell	21-Trachea-Epithelial-Submucosal_gland_basal\|Trachea / Age, Tissue, Lineage and Cell class	EPHB3 COL4A2 CTHRC1 ADAMTS18	3.72e-04	159	95	4	4f670b57b8d3b090ea2f1aafe15baf93cb7ef146
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 LAMA2 TECTA LRP1B	3.81e-04	160	95	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA12 LAMA2 TECTA LRP1B	3.81e-04	160	95	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 ATRNL1 LAMA2 C1R	4.00e-04	162	95	4	5f009b231f21861afee9cc0c569082e1135f929c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A2 ATRNL1 LAMA2 C1R	4.00e-04	162	95	4	b936f8040dcd4db621ccded19237af8df7d0ed6e
ToppCell	droplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEMA4D CSNK1G1 CYFIP2 EPHA4	4.00e-04	162	95	4	93bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	WWP1 SLC40A1 ITGB5 CD163	4.09e-04	163	95	4	4b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL4A2 STARD9 TECTA LRP1B	4.09e-04	163	95	4	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	Club-club-16\|World / Class top	CELF5 LIMS1 CLIC1 STK35	4.28e-04	165	95	4	684f3c4872bd630d3f744f15d57dccfd34e96160
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 F2 LRP1B EXOC4	4.28e-04	165	95	4	0edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STAB2 ITGB5 SHC3 CD163	4.28e-04	165	95	4	6dda1c7fd812792bd2e4fb1a7ccb82a3552b0a3b
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR2 F2 LRP1B EXOC4	4.28e-04	165	95	4	fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell	Basal_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	EPHB3 CELSR2 ABCA12 PLCH2	4.58e-04	168	95	4	48089fa2d4a0f31a72405717119b767a92571f01
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EPHB3 COL4A2 SLC15A2 GART	4.69e-04	169	95	4	c6e5b179461996ced6c7621dc01cec00d401f4e8
ToppCell	3'_v3-Lung-Lymphocytic_B_plasma\|Lung / Manually curated celltypes from each tissue	STAB2 EPHA6 BUB1 CTHRC1	4.69e-04	169	95	4	a65853ff9f6489cc1617cbba0d03b392d23c1528
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	EPHB3 COL4A2 SLC15A2 GART	4.69e-04	169	95	4	ea600c63cf9572bc4b3cad6392f67bd0d92c7fc9
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CELSR2 DSC3 WFDC5 CSMD1	4.90e-04	171	95	4	121e63ca281ad765d76c2afb3b4d441329b47f81
Drug	glycyl-l-glutamine	SLC15A2 GLUD1 GLUD2 SLC40A1	2.72e-06	24	94	4	CID000123913
Drug	tridecane	CLIC1 GLUD1 PEG3 GLUD2 DLK1 FKBP1B	1.00e-05	119	94	6	CID000012388
Drug	Tridihexethyl chloride; Down 200; 11.4uM; MCF7; HT_HG-U133A	PTPN12 ATXN7L3B CSNK1G1 GART BUB1 TRMT2B TOP3A	1.50e-05	192	94	7	3526_DN
Drug	phenyltriethoxysilane	GLUD1 GLUD2	1.69e-05	2	94	2	CID000013075
Drug	G-3SH	GLUD1 GLUD2	1.69e-05	2	94	2	CID000174237
Drug	iodoacetyldiethylstilbestrol	GLUD1 GLUD2	1.69e-05	2	94	2	CID006455327
Drug	methylmercuric bromide	GLUD1 GLUD2	1.69e-05	2	94	2	CID000068175
Drug	5-methylisophthalate	GLUD1 GLUD2	1.69e-05	2	94	2	CID000068137
Drug	x 1 s	GLUD1 GLUD2	1.69e-05	2	94	2	CID000409694
Drug	C75; Up 200; 10uM; MCF7; HT_HG-U133A	COL4A2 DSC3 PLCH2 TECTA TOP3A CD163 INVS	1.89e-05	199	94	7	6394_UP
Drug	protopine	GLUD1 GLUD2 F2	2.99e-05	15	94	3	CID000004970
Drug	lenthionine	GLUD1 GLUD2	5.05e-05	3	94	2	CID000067521
Drug	mildiomycin	GLUD1 GLUD2	5.05e-05	3	94	2	CID000125665
Drug	methoxyethylmercury	GLUD1 GLUD2	5.05e-05	3	94	2	CID000115155
Drug	4-methylumbelliferyl laurate	GLUD1 GLUD2	5.05e-05	3	94	2	CID000600674
Drug	methylmercuric iodide	GLUD1 GLUD2	5.05e-05	3	94	2	CID000067347
Drug	U285	GZMH GLUD1 GLUD2 NLE1 WFDC5	8.59e-05	108	94	5	CID000009475
Drug	N V A	GZMH GLUD1 GLUD2 F2	9.75e-05	58	94	4	CID000000824
Drug	methyl benzoquate	GLUD1 GLUD2	1.01e-04	4	94	2	CID000026383
Drug	pentenoic acid	GLUD1 GLUD2	1.01e-04	4	94	2	CID000012299
Drug	alpha-ketoglutaramate	GLUD1 GLUD2	1.01e-04	4	94	2	CID000000048
Drug	ureidoglycine	GLUD1 GLUD2	1.01e-04	4	94	2	CID000439649
Drug	Ivin	GLUD1 GLUD2	1.01e-04	4	94	2	CID000014083
Drug	8-BDB-TADP	GLUD1 GLUD2	1.01e-04	4	94	2	CID000130791
Drug	cadina-3,9-diene	GLUD1 GLUD2	1.01e-04	4	94	2	CID000010657
Drug	AC1L9CUQ	GLUD1 GLUD2	1.01e-04	4	94	2	CID000442451
Drug	luxabendazole	GLUD1 GLUD2	1.01e-04	4	94	2	CID000072019
Drug	N-butylmaleimide	GLUD1 GLUD2	1.01e-04	4	94	2	CID000239780
Drug	alpha-methylglutamate	GLUD1 GLUD2	1.01e-04	4	94	2	CID000095440
Drug	2b E2	GLUD1 GLUD2	1.01e-04	4	94	2	CID005327076
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A	EPHB3 PTPN12 ATXN7L3B GART BUB1 TOP3A	1.38e-04	190	94	6	1636_DN
Drug	Oxamniquine [21738-42-1]; Down 200; 14.4uM; MCF7; HT_HG-U133A	PTPN12 STAB2 CSNK1G1 MMP14 ITGB5 TOP3A	1.42e-04	191	94	6	4124_DN
Drug	Trifluoperazine dihydrochloride [440-17-5]; Down 200; 8.4uM; MCF7; HT_HG-U133A	SEMA4D DDX52 GART FTSJ1 MMP14 TOP3A	1.42e-04	191	94	6	5442_DN
Drug	indole-3-pyruvic acid	GLUD1 GLUD2 WFDC5	1.47e-04	25	94	3	CID000000803
Drug	(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A	EPHB3 DDX52 ATXN7L3B MMP14 MAST2 EPHA4	1.55e-04	194	94	6	4524_DN
Drug	Ornidazole [16773-42-5]; Down 200; 18.2uM; MCF7; HT_HG-U133A	OSBP PTPN12 CSNK1G1 GART BUB1 MAST2	1.55e-04	194	94	6	5483_DN
Drug	Acetylsalicylsalicylic acid [530-75-6]; Down 200; 13.4uM; MCF7; HT_HG-U133A	PTPN12 DDX52 NLE1 MAST2 ITGB5 TOP3A	1.59e-04	195	94	6	2223_DN
Drug	bathocuproine	GLUD1 GLUD2	1.67e-04	5	94	2	CID000065149
Drug	AC1NRA4I	GLUD1 GLUD2	1.67e-04	5	94	2	CID005287695
Drug	isosteviol lactone	GLUD1 GLUD2	1.67e-04	5	94	2	CID000401559
Drug	1-pheg	GLUD1 GLUD2	1.67e-04	5	94	2	CID000152041
Drug	5'-FSBAzA	GLUD1 GLUD2	1.67e-04	5	94	2	CID000130430
Drug	adenine N1-oxide	GLUD1 GLUD2	1.67e-04	5	94	2	CID000093557
Drug	silicon cation	FEZF2 PEG3	1.67e-04	5	94	2	CID016019983
Drug	choline sulfate	GLUD1 GLUD2	1.67e-04	5	94	2	CID000000485
Drug	l-413	GLUD1 GLUD2	1.67e-04	5	94	2	CID000012475
Drug	3-aminopicolinate	GLUD1 GLUD2	1.67e-04	5	94	2	CID000073836
Drug	Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A	DDX52 ATXN7L3B NLE1 TRMT2B TOP3A CYFIP2	1.68e-04	197	94	6	5292_DN
Drug	Folinic acid calcium salt [6035-45-6]; Up 200; 7.8uM; MCF7; HT_HG-U133A	GART BUB1 MMP14 MAST2 TOP3A CYFIP2	1.68e-04	197	94	6	3442_UP
Drug	dexamethasone; Up 200; 1uM; MCF7; HG-U133A	COL4A2 STAB2 DDX52 PEG3 CASP9 MAST2	1.68e-04	197	94	6	255_UP
Drug	Norgestrel-(-)-D [797-63-7]; Down 200; 12.8uM; MCF7; HT_HG-U133A	SEMA4D SLC15A2 ATXN7L3B CASP9 TOP3A EPHA4	1.68e-04	197	94	6	3406_DN
Drug	2-propylpentanoic acid; Up 200; 200uM; MCF7; HT_HG-U133A	SEMA4D PTPN12 STAB2 FBXL18 PLCH2 INVS	1.73e-04	198	94	6	5211_UP
Drug	L(-)-vesamicol hydrochloride [112709-59-8]; Down 200; 13.6uM; PC3; HT_HG-U133A	DAZAP1 PEG3 GART BUB1 MMP14 CYFIP2	1.73e-04	198	94	6	5056_DN
Drug	Ungerine nitrate; Up 200; 10.2uM; HL60; HT_HG-U133A	KMT2D CELSR2 ADAM18 ATRNL1 ITGB5 CSDC2	1.78e-04	199	94	6	2514_UP
Drug	Pyrantel tartrate [33401-94-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A	EPHB3 ZCWPW1 FBXL18 CASP9 MAST2 TOP3A	1.78e-04	199	94	6	5513_DN
Drug	Eucatropine hydrochloride [536-93-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	RPGRIP1L CELSR2 CSNK1G1 BUB1 MMP14 TOP3A	1.78e-04	199	94	6	3759_DN
Drug	Pentolinium bitartrate [52-62-0]; Up 200; 7.4uM; HL60; HT_HG-U133A	CELSR2 SLC15A2 DDX52 NLE1 TECTA MAST2	1.78e-04	199	94	6	2343_UP
Drug	Cefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; HL60; HT_HG-U133A	ZCWPW1 FBXL18 DSC3 GRK4 MAST2 CYFIP2	1.83e-04	200	94	6	2988_DN
Drug	alpha-monofluoromethylputrescine	GLUD1 GLUD2	2.50e-04	6	94	2	CID000134201
Drug	dimethylmalonate	GLUD1 GLUD2	2.50e-04	6	94	2	CID000007943
Drug	2-methyl-1,2,3,4-tetrahydroisoquinoline	GLUD1 GLUD2	2.50e-04	6	94	2	CID000015362
Drug	lanosol	GLUD1 GLUD2	2.50e-04	6	94	2	CID000078659
Drug	dadAB	GLUD1 GLUD2	2.50e-04	6	94	2	CID000022626
Drug	N-methylhydantoin	GLUD1 GLUD2	2.50e-04	6	94	2	CID000069217
Drug	diazonium-1-H-tetrazole	GLUD1 GLUD2	2.50e-04	6	94	2	CID000188312
Drug	AC1L448Y	GLUD1 GLUD2	2.50e-04	6	94	2	CID000200389
Drug	2-BDB-TAMP	GLUD1 GLUD2	2.50e-04	6	94	2	CID000127220
Drug	Emid	GLUD1 GLUD2	2.50e-04	6	94	2	CID000074798
Drug	AC1L8SA5	GLUD1 GLUD2	2.50e-04	6	94	2	CID000407285
Drug	isodiazinon	GLUD1 GLUD2	2.50e-04	6	94	2	CID000133913
Drug	diisopropylphosphate	CSNK1G3 CSNK1G1 F2	2.55e-04	30	94	3	CID000074162
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	2.82e-05	3	91	2	DOID:885 (biomarker_via_orthology)
Disease	colorectal cancer (is_implicated_in)	PTPN12 XPO5 BUB1 CASP9 LRP1B	3.74e-05	121	91	5	DOID:9256 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_implicated_in)	KMT2D FOXL2 XPO5 CASP9 LRP1B	7.25e-05	139	91	5	DOID:3908 (is_implicated_in)
Disease	Paratuberculosis	C1R F2	1.40e-04	6	91	2	C0030524
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	1.40e-04	6	91	2	DOID:1825 (biomarker_via_orthology)
Disease	venous thromboembolism, von Willebrand factor measurement	STAB2 SLC44A2 F2	2.99e-04	42	91	3	EFO_0004286, EFO_0004629
Disease	Nephronophthisis	RPGRIP1L INVS	3.34e-04	9	91	2	cv:C0687120
Disease	microfibrillar-associated protein 2 measurement	A2ML1 C1R	5.08e-04	11	91	2	EFO_0801801
Disease	cortical thickness	COL4A2 CELF5 SEMA4D XPO5 LAMA2 ADAMTS18 SYBU MAST2 ITGB5 EPHA4 EXOC4	6.28e-04	1113	91	11	EFO_0004840
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	9.62e-04	15	91	2	DOID:13413 (biomarker_via_orthology)
Disease	Liver carcinoma	STAB2 FBXL18 BCO2 BUB1 CSMD1 F2 CD163	9.91e-04	507	91	7	C2239176
Disease	Ischemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism	SLC44A2 F2	1.24e-03	17	91	2	EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Disease	thyroid peroxidase antibody measurement	ATRNL1 MAGI3 EXOC4	1.45e-03	72	91	3	EFO_0005666
Disease	diet measurement	SEMA4D CELSR2 ATXN7L3B LAMA2 CSMD1 F2 LRP1B ZIC1 EPHA4 EXOC4	1.47e-03	1049	91	10	EFO_0008111
Disease	Colorectal Carcinoma	OSBP FOXL2 ABCA12 FSTL5 PEG3 BUB1 ADAMTS18 EXOC4	1.48e-03	702	91	8	C0009402
Disease	glomerulonephritis (is_marker_for)	F2 CD163	1.55e-03	19	91	2	DOID:2921 (is_marker_for)
Disease	nicotine dependence symptom count, depressive symptom measurement	FSTL5 NLE1 DLK1	1.63e-03	75	91	3	EFO_0007006, EFO_0009262
Disease	Fetal Growth Retardation	GLUD1 DLK1	1.72e-03	20	91	2	C0015934
Disease	otosclerosis	COL4A2 SEMA4D LTBP3	2.03e-03	81	91	3	EFO_0004213
Disease	QRS duration, response to sulfonylurea	MDN1 CSMD1	2.28e-03	23	91	2	EFO_0005055, EFO_0007922
Disease	severe acute respiratory syndrome, COVID-19	COL4A2 GCNT7 GRK4 LTBP3 CSMD1 LRP1B	2.64e-03	447	91	6	EFO_0000694, MONDO_0100096
Disease	Endogenous Hyperinsulinism	GLUD1 CD163	2.91e-03	26	91	2	C1257963
Disease	Exogenous Hyperinsulinism	GLUD1 CD163	2.91e-03	26	91	2	C1257964
Disease	Compensatory Hyperinsulinemia	GLUD1 CD163	2.91e-03	26	91	2	C1257965

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDFFGNKKSVPGVCG	DDX52	46	Q9Y2R4
VKNEGGECKPEGLFR	BUB1	1006	O43683
KAVYQEIEKGGCGDP	CSMD1	516	Q96PZ7
PGRDGFKGEKGECLR	CTHRC1	81	Q96CG8
VKDFGIQPVEDKGAC	ATXN7L3B	56	Q96GX2
PDKGNLLGRFCGKVP	CDCP2	96	Q5VXM1
ERFGCAEVKPEKSNG	ABCA12	1296	Q86UK0
QCAKIFGKGAQGAPF	ADAM18	501	Q9Y3Q7
TGFKGDSGGPLVCKD	GZMH	196	P20718
CGGQKGFVPQKGRSD	A2ML1	881	A8K2U0
VLAGVKKFDVPCGGR	COL4A2	31	P08572
CAAQRQGFEKKGPVS	CELSR2	2546	Q9HCU4
GKDCQKKDGPCVING	DLK1	121	P80370
GNTPQKKAVFGQCRG	BCO2	36	Q9BYV7
GKNIGEFCGKQRPPD	C1R	261	P00736
RGFGFVKFKDPNCVG	DAZAP1	51	Q96EP5
GGGVKFQERHCNNPK	ADAMTS18	606	Q8TE60
PRCGVPDKFGAEIKA	MMP14	91	P50281
GKELEGKGQKACPTR	MDN1	3481	Q9NU22
GFNLGSDGRSCKRPK	LRP1B	506	Q9NZR2
IEGSPADRCGKLKVG	MAGI3	886	Q5TCQ9
KRGCDEGFQPLGEVI	GIGYF1	511	O75420
GAGAGPQCEKTVDVK	nan	11	A8MVJ9
ENAGLQECPRKGIKF	RPGRIP1L	166	Q68CZ1
GPNFRVGKKIGCGNF	CSNK1G1	41	Q9HCP0
EFGEVCSGRLKVPGK	EPHA4	631	P54764
FGRKDKGQDPDACDV	PERCC1	101	A0A1W2PR82
CFIKVPREGGGERKG	FOXL2	111	P58012
GIVNGKILCPFDADG	KCTD4	61	Q8WVF5
AGEFGEVCRGRLKQP	EPHB3	641	P54753
DRCRPGKFGLDAKNP	LAMA2	1146	P24043
CLRGEKDPKGGFDIK	CYFIP2	531	Q96F07
SYPGQRKCEGLKIGD	ITGB5	406	P18084
PNFRVGKKIGCGNFG	CSNK1G3	41	Q9Y6M4
ECFKVQPVIGENGGD	OSBP	651	P22059
RGNPFENKGKVCEET	PEG3	651	Q9GZU2
KLLGFQDEVCPKAEG	FSTL5	481	Q8N475
KECPEIGPFAGRGQK	BOD1L1	2436	Q8NFC6
EGGGTKFVCKPGARN	EXOC4	481	Q96A65
DIGKGPEERQFKGLG	SLC25A31	156	Q9H0C2
VCGVFGATKGKRFPE	DSC3	711	Q14574
LFEGKGAAPQIAKFC	GCNT7	56	Q6ZNI0
GDGRTFPKKGQTCVV	FKBP1B	11	P68106
KCAVVDVPFGGAKAG	GLUD1	171	P00367
GGKPKLFFIQACGGE	CASP9	276	P55211
CKNIGVDDVGKDIGP	CCDC73	951	Q6ZRK6
LRGPDGSSKGCAFVK	CELF5	166	Q8N6W0
KAFRDEELCKNAGPG	ATRNL1	616	Q5VV63
DGTAAFKEICPAGKG	LTBP3	446	Q9NS15
GHAKEGQGIKCDIPR	MAST2	446	Q6P0Q8
PVRKIRADGGVCKNG	GK5	431	Q6ZS86
PTDSRGEFCGQKGTK	SLC44A2	66	Q8IWA5
LFCSRNPDFEEKGGK	DDHD1	516	Q8NEL9
ARASAGPVFKGVCKQ	CSDC2	61	Q9Y534
KRLGCRGEGAAGVKQ	GRK4	431	P32298
GCGPALKAFKEAEFG	CD163	971	Q86VB7
KPCVAAFGGDQFEEK	SLC15A2	161	Q16348
KCAVVDVPFGGAKAG	GLUD2	171	P49448
GARPFVCKVCGKGFR	FEZF2	301	Q8TBJ5
GDERCAKGKGFVKQP	INVS	731	Q9Y283
EFGEVCSGRLKTPGK	EPHA6	641	Q9UF33
VFPRKGLDDFRKGCP	FAM47E	46	Q6ZV65
PDGRKLASGCKNGQI	NLE1	166	Q9NVX2
PDGQRVASGGKDKCL	NLE1	466	Q9NVX2
GPRRCFVEFGAGKGK	TRMT13	181	Q9NUP7
IVKEFFIRGPGAACG	TRMT2B	261	Q96GJ1
GGKKAPFRIQEEGAC	FER1L5	441	A0AVI2
VCGLPDGTEKGKFLA	HKDC1	516	Q2TB90
RGFGKKVRVGVQSCP	FBXL18	446	Q96ME1
EATDIGFGNRCGKPK	PTPN12	756	Q05209
SRVCEAVPGAKGAFK	SHC3	186	Q92529
VADPRRCESKKFGGP	RPS16	121	P62249
LGNKLFACGPDAKEV	SLC40A1	546	Q9NP59
LGKNEDGKGRCPFDP	SEMA4D	146	Q92854
CFRDGDLGKEPFKAA	STARD9	2976	Q9P2P6
ERCKGGFAPAEKIVN	LIMS1	11	P48059
FVKAGSDGAKIGNCP	CLIC1	11	O00299
AFKVDGKEIDPANGC	TECTA	246	O75443
ARDAVAVRPGGCGKK	TNRC18	596	O15417
AVFGRKKGEKSGGCP	WFDC5	21	Q8TCV5
KVCAGLAPRGKEGNQ	STK35	386	Q8TDR2
QNKEECGKGPKRIFA	ZCWPW1	6	Q9H0M4
IGFCPGSDEGFTRKK	SYBU	101	Q9NX95
CPENKSKGLLGIDGF	PLCH2	291	O75038
PTKEGCLAFGTDDGK	GEMIN5	436	Q8TEQ6
GCIGKPLGEQFRKEV	XPO5	1156	Q9HAV4
VGPGQNECECKKGFR	STAB2	931	Q8WWQ8
KKGFRGNGIDCEPIT	STAB2	941	Q8WWQ8
KNGPKVLEFNCRFGD	GART	281	P22102
KEGPNRGRQFFKCNG	TOP3A	826	Q13472
SGEKPIVCKDCGRGF	ZNF133	461	P52736
CGPEAGGCRENKQKR	TOPAZ1	36	Q8N9V7
VLKPGGCFVAKIFRG	FTSJ1	146	Q9UET6
FPGCGKVFARSENLK	ZIC1	306	Q15915
AGYKPDEGKRGDACE	F2	551	P00734
GSNGPQKFCIEKVGK	WWP1	866	Q9H0M0
KFDVCKPGDGQLPEG	TBRG1	321	Q3YBR2
GQEGPELCGVDKAIF	KMT2D	151	O14686