Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	carbohydrate binding	MGAM GANC CALR APCS FBXO2 PLA2R1 CLEC20A MRC2 ASGR2 LY75 CLEC12B	5.37e-07	310	102	11	GO:0030246
GeneOntologyMolecularFunction	group II metabotropic glutamate receptor activity	GRM2 GRM3	2.58e-05	2	102	2	GO:0001641
GeneOntologyMolecularFunction	cytokine receptor activity	IFNLR1 CD4 CSF2RA CSF2RB OSMR	1.40e-04	97	102	5	GO:0004896
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM GANC	2.56e-04	5	102	2	GO:0004558
GeneOntologyMolecularFunction	opsonin binding	CALR APCS MASP2	2.74e-04	25	102	3	GO:0001846
GeneOntologyMolecularFunction	peptidase activity	PCSK2 ADAMTS3 CAPN1 DPP3 XPNPEP2 LAP3 GZMA USP40 ADAMTS14 ADAMTSL2 MASP2	5.11e-04	654	102	11	GO:0008233
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM GANC	5.34e-04	7	102	2	GO:0090599
GeneOntologyMolecularFunction	metallopeptidase activity	ADAMTS3 DPP3 XPNPEP2 LAP3 ADAMTS14 ADAMTSL2	5.68e-04	200	102	6	GO:0008237
GeneOntologyMolecularFunction	complement binding	CALR APCS MASP2	5.76e-04	32	102	3	GO:0001848
GeneOntologyMolecularFunction	phospholipase binding	DGKQ PLA2R1 FYN	5.76e-04	32	102	3	GO:0043274
GeneOntologyMolecularFunction	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	MAN1C1 MAN1A2	7.09e-04	8	102	2	GO:0004571
GeneOntologyMolecularFunction	morphogen activity	WNT1 NODAL	7.09e-04	8	102	2	GO:0016015
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM2 GRM3	9.09e-04	9	102	2	GO:0098988
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM2 GRM3	9.09e-04	9	102	2	GO:0001640
GeneOntologyMolecularFunction	complement component C1q complex binding	CALR APCS	1.13e-03	10	102	2	GO:0001849
GeneOntologyMolecularFunction	mannosyl-oligosaccharide mannosidase activity	MAN1C1 MAN1A2	1.13e-03	10	102	2	GO:0015924
GeneOntologyMolecularFunction	scaffold protein binding	GRM2 GRM3 DLGAP3 FYN	1.32e-03	93	102	4	GO:0097110
GeneOntologyMolecularFunction	aminopeptidase activity	DPP3 XPNPEP2 LAP3	1.38e-03	43	102	3	GO:0004177
GeneOntologyMolecularFunction	immune receptor activity	IFNLR1 CD4 CSF2RA CSF2RB OSMR	1.58e-03	165	102	5	GO:0140375
GeneOntologyMolecularFunction	dynactin binding	SPTBN5 HTT	1.65e-03	12	102	2	GO:0034452
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	MGAM GANC MAN1C1 MAN1A2	1.93e-03	103	102	4	GO:0004553
GeneOntologyMolecularFunction	alpha-mannosidase activity	MAN1C1 MAN1A2	2.60e-03	15	102	2	GO:0004559
GeneOntologyMolecularFunction	glucosidase activity	MGAM GANC	2.60e-03	15	102	2	GO:0015926
GeneOntologyMolecularFunction	calcium channel regulator activity	REM1 GRM2 GRM3	2.66e-03	54	102	3	GO:0005246
GeneOntologyMolecularFunction	mannosidase activity	MAN1C1 MAN1A2	2.96e-03	16	102	2	GO:0015923
GeneOntologyBiologicalProcess	endocytosis	CALR DGKQ PLA2R1 SCAMP5 MRC2 ASGR2 ARFGAP1 DMBT1 FGR LY75 SNX9 FYN VAV1 EPHA3	3.99e-05	827	99	14	GO:0006897
GeneOntologyBiologicalProcess	G protein-coupled glutamate receptor signaling pathway	GRM2 GRM3 FYN	5.74e-05	16	99	3	GO:0007216
GeneOntologyBiologicalProcess	maltose metabolic process	MGAM GANC	6.82e-05	3	99	2	GO:0000023
GeneOntologyBiologicalProcess	T cell costimulation	TNFSF14 CD5 FYN VAV1	1.05e-04	51	99	4	GO:0031295
GeneOntologyBiologicalProcess	lymphocyte costimulation	TNFSF14 CD5 FYN VAV1	1.22e-04	53	99	4	GO:0031294
GeneOntologyBiologicalProcess	granulocyte-macrophage colony-stimulating factor signaling pathway	CSF2RA CSF2RB	1.36e-04	4	99	2	GO:0038157
GeneOntologyCellularComponent	external side of plasma membrane	ROBO4 CALR CD4 CD5 CSF2RA CSF2RB ASGR2 ASTN1 OSMR ADGRE1 LY75 CLEC12B	6.99e-06	519	100	12	GO:0009897
GeneOntologyCellularComponent	cell surface	ROBO4 CALR WNT1 DSCAML1 PLA2R1 CD4 CD5 CSF2RA CSF2RB LMO7 MRC2 ASGR2 ASTN1 OSMR ADGRE1 LY75 CLEC12B	1.94e-05	1111	100	17	GO:0009986
GeneOntologyCellularComponent	side of membrane	ROBO4 CALR XPNPEP2 CD4 CD5 CSF2RA CSF2RB NPTXR ASGR2 ASTN1 OSMR ADGRE1 LY75 CLEC12B	7.11e-05	875	100	14	GO:0098552
GeneOntologyCellularComponent	granulocyte macrophage colony-stimulating factor receptor complex	CSF2RA CSF2RB	1.35e-04	4	100	2	GO:0030526
Domain	Galactose-bd-like	PCSK2 CNTNAP3B CNTNAP3 F5 FBXO2 HERC2 EPHA3	6.22e-07	94	98	7	IPR008979
Domain	FN3	ROBO4 SPEG DSCAML1 IFNLR1 CSF2RA CSF2RB ASTN1 OSMR EPHA3	1.03e-06	199	98	9	PS50853
Domain	FN3_dom	ROBO4 SPEG DSCAML1 IFNLR1 CSF2RA CSF2RB ASTN1 OSMR EPHA3	1.54e-06	209	98	9	IPR003961
Domain	-	PCSK2 CNTNAP3 F5 FBXO2 HERC2 EPHA3	2.29e-06	73	98	6	2.60.120.260
Domain	PLAC	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	2.60e-06	19	98	4	PS50900
Domain	PLAC	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	2.60e-06	19	98	4	IPR010909
Domain	ADAM_spacer1	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	5.85e-06	23	98	4	IPR010294
Domain	ADAM_spacer1	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	5.85e-06	23	98	4	PF05986
Domain	FN3	ROBO4 SPEG DSCAML1 CSF2RA CSF2RB ASTN1 OSMR EPHA3	5.86e-06	185	98	8	SM00060
Domain	Peptidase_M12B_ADAM-TS	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	6.99e-06	24	98	4	IPR013273
Domain	M_domain	TNRC6C TNRC6A	2.73e-05	2	98	2	PF12938
Domain	GW182_M_dom	TNRC6C TNRC6A	2.73e-05	2	98	2	IPR026805
Domain	FN_type2_col-bd	PLA2R1 MRC2 LY75	4.89e-05	14	98	3	IPR000562
Domain	FN2_2	PLA2R1 MRC2 LY75	4.89e-05	14	98	3	PS51092
Domain	fn2	PLA2R1 MRC2 LY75	4.89e-05	14	98	3	PF00040
Domain	FN2_1	PLA2R1 MRC2 LY75	4.89e-05	14	98	3	PS00023
Domain	FN2	PLA2R1 MRC2 LY75	4.89e-05	14	98	3	SM00059
Domain	C_TYPE_LECTIN_1	PLA2R1 MRC2 ASGR2 LY75 CLEC12B	6.32e-05	80	98	5	PS00615
Domain	C-type_lectin_CS	PLA2R1 MRC2 ASGR2 LY75	7.52e-05	43	98	4	IPR018378
Domain	Lectin_C	PLA2R1 MRC2 ASGR2 LY75 CLEC12B	7.98e-05	84	98	5	PF00059
Domain	CLECT	PLA2R1 MRC2 ASGR2 LY75 CLEC12B	7.98e-05	84	98	5	SM00034
Domain	Ago_hook	TNRC6C TNRC6A	8.15e-05	3	98	2	PF10427
Domain	TNRC6_PABC-bd	TNRC6C TNRC6A	8.15e-05	3	98	2	IPR032226
Domain	Argonaute_hook_dom	TNRC6C TNRC6A	8.15e-05	3	98	2	IPR019486
Domain	TNRC6-PABC_bdg	TNRC6C TNRC6A	8.15e-05	3	98	2	PF16608
Domain	C_TYPE_LECTIN_2	PLA2R1 MRC2 ASGR2 LY75 CLEC12B	8.45e-05	85	98	5	PS50041
Domain	C-type_lectin-like	PLA2R1 MRC2 ASGR2 LY75 CLEC12B	8.93e-05	86	98	5	IPR001304
Domain	C-type_lectin-like/link	PLA2R1 MRC2 ASGR2 LY75 CLEC12B	1.74e-04	99	98	5	IPR016186
Domain	FA58C	CNTNAP3B CNTNAP3 F5	1.74e-04	21	98	3	SM00231
Domain	SRCR	SSC4D CD5 DMBT1	1.74e-04	21	98	3	PF00530
Domain	FA58C_3	CNTNAP3B CNTNAP3 F5	1.74e-04	21	98	3	PS50022
Domain	FA58C_1	CNTNAP3B CNTNAP3 F5	1.74e-04	21	98	3	PS01285
Domain	FA58C_2	CNTNAP3B CNTNAP3 F5	1.74e-04	21	98	3	PS01286
Domain	-	ROBO4 SPEG PAPLN DSCAML1 IFNLR1 VSTM4 CD4 CSF2RA CSF2RB ASTN1 OSMR EPHA3	1.81e-04	663	98	12	2.60.40.10
Domain	fn3	ROBO4 SPEG DSCAML1 CSF2RB OSMR EPHA3	2.12e-04	162	98	6	PF00041
Domain	CTDL_fold	PLA2R1 MRC2 ASGR2 LY75 CLEC12B	2.50e-04	107	98	5	IPR016187
Domain	F5_F8_type_C	CNTNAP3B CNTNAP3 F5	2.62e-04	24	98	3	PF00754
Domain	FA58C	CNTNAP3B CNTNAP3 F5	2.62e-04	24	98	3	IPR000421
Domain	SR	SSC4D CD5 DMBT1	2.96e-04	25	98	3	SM00202
Domain	-	SSC4D CD5 DMBT1	2.96e-04	25	98	3	3.10.250.10
Domain	Ig-like_fold	ROBO4 SPEG PAPLN DSCAML1 IFNLR1 VSTM4 CD4 CSF2RA CSF2RB ASTN1 OSMR EPHA3	3.21e-04	706	98	12	IPR013783
Domain	SRCR_1	SSC4D CD5 DMBT1	3.34e-04	26	98	3	PS00420
Domain	SRCR_2	SSC4D CD5 DMBT1	3.34e-04	26	98	3	PS50287
Domain	SRCR-like_dom	SSC4D CD5 DMBT1	3.34e-04	26	98	3	IPR017448
Domain	TSP_1	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	3.35e-04	63	98	4	PF00090
Domain	SRCR	SSC4D CD5 DMBT1	3.74e-04	27	98	3	IPR001190
Domain	TSP1	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	3.78e-04	65	98	4	SM00209
Domain	TSP1_rpt	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	3.78e-04	65	98	4	IPR000884
Domain	TSP1	ADAMTS3 PAPLN ADAMTS14 ADAMTSL2	3.78e-04	65	98	4	PS50092
Domain	Glyco_hydro_31_AS	MGAM GANC	4.03e-04	6	98	2	IPR030458
Domain	RICIN	PLA2R1 MRC2 LY75	4.17e-04	28	98	3	SM00458
Domain	RICIN_B_LECTIN	PLA2R1 MRC2 LY75	4.17e-04	28	98	3	PS50231
Domain	EGF_2	CNTNAP3B CNTNAP3 PGAP6 ASTN1 ADGRE1 EPHA3 MASP2	4.93e-04	265	98	7	PS01186
Domain	Ricin_B_lectin	PLA2R1 MRC2 LY75	5.13e-04	30	98	3	IPR000772
Domain	Glyco_hydro_31	MGAM GANC	5.63e-04	7	98	2	IPR000322
Domain	Glyco_hydro_47	MAN1C1 MAN1A2	5.63e-04	7	98	2	PF01532
Domain	-	MAN1C1 MAN1A2	5.63e-04	7	98	2	1.50.10.50
Domain	Glyco_hydro_31	MGAM GANC	5.63e-04	7	98	2	PF01055
Domain	GLYCOSYL_HYDROL_F31_1	MGAM GANC	5.63e-04	7	98	2	PS00129
Domain	Kringle-like	PLA2R1 MRC2 LY75	6.22e-04	32	98	3	IPR013806
Domain	GPCR_3_mtglu_rcpt	GRM2 GRM3	7.48e-04	8	98	2	IPR000162
Domain	Glyco_hydro_47	MAN1C1 MAN1A2	7.48e-04	8	98	2	IPR001382
Domain	PENTAXIN	APCS NPTXR	9.58e-04	9	98	2	PS00289
Domain	SH3	MPP1 EPS8 FGR SNX9 FYN VAV1	9.71e-04	216	98	6	SM00326
Domain	SH3	MPP1 EPS8 FGR SNX9 FYN VAV1	9.71e-04	216	98	6	PS50002
Domain	SH3_domain	MPP1 EPS8 FGR SNX9 FYN VAV1	1.07e-03	220	98	6	IPR001452
Domain	PTX	APCS NPTXR	1.19e-03	10	98	2	SM00159
Domain	Pentaxin-related	APCS NPTXR	1.45e-03	11	98	2	IPR001759
Domain	Pentaxin	APCS NPTXR	1.45e-03	11	98	2	PF00354
Domain	IL6Ra-bind	CSF2RA CSF2RB	1.45e-03	11	98	2	PF09240
Domain	SM22_calponin	LMO7 VAV1	1.45e-03	11	98	2	IPR003096
Domain	TypeI_recpt_CBD	CSF2RA CSF2RB	1.45e-03	11	98	2	IPR015321
Domain	EGF_3	CNTNAP3B CNTNAP3 PGAP6 ASTN1 ADGRE1 MASP2	1.50e-03	235	98	6	PS50026
Domain	EGF	CNTNAP3B CNTNAP3 PGAP6 ASTN1 ADGRE1 MASP2	1.50e-03	235	98	6	SM00181
Domain	-	CALR CNTNAP3 APCS NPTXR	1.57e-03	95	98	4	2.60.120.200
Domain	-	PLA2R1 MRC2 ASGR2 CLEC12B	1.70e-03	97	98	4	3.10.100.10
Domain	SH3_1	EPS8 FGR SNX9 FYN VAV1	1.73e-03	164	98	5	PF00018
Domain	EGF-like_dom	CNTNAP3B CNTNAP3 PGAP6 ASTN1 ADGRE1 MASP2	2.00e-03	249	98	6	IPR000742
Domain	NCD3G	GRM2 GRM3	2.05e-03	13	98	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM2 GRM3	2.05e-03	13	98	2	IPR011500
Domain	-	PLA2R1 MRC2	2.05e-03	13	98	2	2.10.10.10
Domain	EGF_1	CNTNAP3B CNTNAP3 PGAP6 ASTN1 ADGRE1 MASP2	2.26e-03	255	98	6	PS00022
Domain	PLAC	PAPLN ADAMTSL2	2.38e-03	14	98	2	PF08686
Domain	GPCR_3_CS	GRM2 GRM3	2.38e-03	14	98	2	IPR017979
Domain	Gal_mutarotase_SF_dom	MGAM GANC	3.52e-03	17	98	2	IPR011013
Domain	UBA-like	TNRC6C UBAP2L TNRC6A	4.63e-03	64	98	3	IPR009060
Domain	CH	SPTBN5 LMO7 VAV1	4.84e-03	65	98	3	SM00033
Pathway	REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING	CSF2RA CSF2RB FYN VAV1	1.27e-04	48	76	4	M914
Pathway	KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY	CD4 FYN VAV1	1.37e-04	19	76	3	M47733
Pathway	BIOCARTA_ERAD_PATHWAY	MAN1C1 FBXO2 MAN1A2	1.37e-04	19	76	3	M22013
Pubmed	Site-specific N-glycosylation and oligosaccharide structures of recombinant HIV-1 gp120 derived from a baculovirus expression system.	GANC MAN1C1 CD4 MAN1A2	1.03e-06	26	103	4	8218172
Pubmed	Sequence- and interactome-based prediction of viral protein hotspots targeting host proteins: a case study for HIV Nef.	CD4 FYN VAV1	1.40e-06	8	103	3	21738584
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS3 PAPLN ADAMTS14 NODAL ADAMTSL2	3.02e-06	75	103	5	20637190
Pubmed	TRIM24 is an insulin-responsive regulator of P-bodies.	TNRC6C ANKHD1 TNRC6A TNKS1BP1 PUM1	4.16e-06	80	103	5	35803934
Pubmed	Biosynthesis and processing of human immunodeficiency virus type 1 envelope glycoproteins: effects of monensin on glycosylation and transport.	GANC MAN1C1 CD4 MAN1A2	4.44e-06	37	103	4	2542563
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	KIF26A SPEG DGKQ PAPLN TNRC6C ANKHD1 IFNLR1 GRAMD2A SLC2A4RG USP40 TNKS1BP1 HERC2 PUM1 HTT	4.88e-06	1105	103	14	35748872
Pubmed	Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1.	GANC MAN1C1 CD4 MAN1A2	4.96e-06	38	103	4	2187500
Pubmed	CD4 cross-linking (CD4XL) induces RAS activation and tumor necrosis factor-alpha secretion in CD4+ T cells.	CD4 FYN VAV1	5.44e-06	12	103	3	9269777
Pubmed	Selective silencing of individual dendritic branches by an mGlu2-activated potassium conductance in dentate gyrus granule cells.	GRM2 GRM3	8.69e-06	2	103	2	23616537
Pubmed	Group II metabotropic glutamate receptor blockade promotes stress resilience in mice.	GRM2 GRM3	8.69e-06	2	103	2	30939596
Pubmed	Salivary agglutinin inhibits HIV type 1 infectivity through interaction with viral glycoprotein 120.	CD4 DMBT1	8.69e-06	2	103	2	12689412
Pubmed	The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/neuroprotection.	GRM2 GRM3	8.69e-06	2	103	2	17670976
Pubmed	The effect of mGlu2/3 receptors on synaptic activities to different types of GABAergic interneurons in the anterior cingulate cortex.	GRM2 GRM3	8.69e-06	2	103	2	32525061
Pubmed	Expression and subcellular distribution of glutamate receptor subunits 2/3 in the developing cerebellar cortex.	GRM2 GRM3	8.69e-06	2	103	2	8838577
Pubmed	Metabotropic Glutamate Receptor 2/3 Activation Improves Motor Performance and Reduces Pathology in Heterozygous zQ175 Huntington Disease Mice.	GRM2 GRM3	8.69e-06	2	103	2	34330748
Pubmed	Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis.	GRM2 GRM3	8.69e-06	2	103	2	25434487
Pubmed	NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication.	GRM2 GRM3	8.69e-06	2	103	2	28285415
Pubmed	mGlu2/3 receptor in the prelimbic cortex is implicated in stress resilience and vulnerability in mice.	GRM2 GRM3	8.69e-06	2	103	2	34090896
Pubmed	Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.	CNTNAP3B CNTNAP3	8.69e-06	2	103	2	26807827
Pubmed	Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice.	GRM2 GRM3	8.69e-06	2	103	2	22089319
Pubmed	Regulation of cocaine-induced reinstatement by group II metabotropic glutamate receptors in the ventral tegmental area.	GRM2 GRM3	8.69e-06	2	103	2	21881873
Pubmed	Fractionation of spatial memory in GRM2/3 (mGlu2/mGlu3) double knockout mice reveals a role for group II metabotropic glutamate receptors at the interface between arousal and cognition.	GRM2 GRM3	8.69e-06	2	103	2	21832989
Pubmed	The role of group II metabotropic glutamate receptors in cognition and anxiety: comparative studies in GRM2(-/-), GRM3(-/-) and GRM2/3(-/-) knockout mice.	GRM2 GRM3	8.69e-06	2	103	2	25158312
Pubmed	Polyglutamine-modulated striatal calpain activity in YAC transgenic huntington disease mouse model: impact on NMDA receptor function and toxicity.	CAPN1 HTT	8.69e-06	2	103	2	19036965
Pubmed	Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells.	FYN VAV1	8.69e-06	2	103	2	9822663
Pubmed	Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice.	GRM2 GRM3	8.69e-06	2	103	2	18720515
Pubmed	Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex.	CSF2RA CSF2RB	8.69e-06	2	103	2	12393492
Pubmed	Cloning of the low-affinity murine granulocyte-macrophage colony-stimulating factor receptor and reconstitution of a high-affinity receptor complex.	CSF2RA CSF2RB	8.69e-06	2	103	2	1533931
Pubmed	Metabotropic glutamate receptor 2/3 in the hippocampus of patients with mesial temporal lobe epilepsy, and of rats and mice after pilocarpine-induced status epilepticus.	GRM2 GRM3	8.69e-06	2	103	2	15246118
Pubmed	Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia.	GRM2 GRM3	8.69e-06	2	103	2	18853337
Pubmed	Hippocampal mossy fiber long-term depression in Grm2/3 double knockout mice.	GRM2 GRM3	8.69e-06	2	103	2	21360593
Pubmed	Developmental expression of mGlu2 and mGlu3 in the mouse brain.	GRM2 GRM3	8.69e-06	2	103	2	27818290
Pubmed	Activation of metabotropic glutamate receptor type 2/3 supports the involvement of the hippocampal mossy fiber pathway on contextual fear memory consolidation.	GRM2 GRM3	8.69e-06	2	103	2	19638469
Pubmed	Enhancement of CA3 hippocampal network activity by activation of group II metabotropic glutamate receptors.	GRM2 GRM3	8.69e-06	2	103	2	21628565
Pubmed	The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.	CNTNAP3B CNTNAP3	8.69e-06	2	103	2	31150793
Pubmed	Decreased striatal dopamine in group II metabotropic glutamate receptor (mGlu2/mGlu3) double knockout mice.	GRM2 GRM3	8.69e-06	2	103	2	24053122
Pubmed	SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition.	SCAMP5 HTT	8.69e-06	2	103	2	19240033
Pubmed	Adaptive Changes in Group 2 Metabotropic Glutamate Receptors Underlie the Deficit in Recognition Memory Induced by Methamphetamine in Mice.	GRM2 GRM3	8.69e-06	2	103	2	38969501
Pubmed	Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease.	CSF2RA CSF2RB	8.69e-06	2	103	2	30124884
Pubmed	Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction.	GRM2 GRM3	8.69e-06	2	103	2	25583490
Pubmed	The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior.	GRM2 GRM3	8.69e-06	2	103	2	23624743
Pubmed	Deletion of Metabotropic Glutamate Receptors 2 and 3 (mGlu2 & mGlu3) in Mice Disrupts Sleep and Wheel-Running Activity, and Increases the Sensitivity of the Circadian System to Light.	GRM2 GRM3	8.69e-06	2	103	2	25950516
Pubmed	Association analysis of group II metabotropic glutamate receptor genes (GRM2 and GRM3) with mood disorders and fluvoxamine response in a Japanese population.	GRM2 GRM3	8.69e-06	2	103	2	19386277
Pubmed	The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells.	GRM2 GRM3	8.69e-06	2	103	2	7965099
Pubmed	Glutamate receptors and the regulation of steroidogenesis in the human adrenal gland: the metabotropic pathway.	GRM2 GRM3	8.69e-06	2	103	2	24080311
Pubmed	The Gammaherpesvirus m2 protein manipulates the Fyn/Vav pathway through a multidocking mechanism of assembly.	FYN VAV1	8.69e-06	2	103	2	18301737
Pubmed	Genome-wide association study of suicidal ideation emerging during citalopram treatment of depressed outpatients.	PAPLN IFNLR1	8.69e-06	2	103	2	19724244
Pubmed	Activation of Group II Metabotropic Glutamate Receptors Promotes LTP Induction at Schaffer Collateral-CA1 Pyramidal Cell Synapses by Priming NMDA Receptors.	GRM2 GRM3	8.69e-06	2	103	2	27911756
Pubmed	Negative regulation of CD4 lineage development and responses by CD5.	CD4 CD5	8.69e-06	2	103	2	10586041
Pubmed	Reduction of group II metabotropic glutamate receptors during development of benzodiazepine dependence.	GRM2 GRM3	8.69e-06	2	103	2	23392308
Pubmed	Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice.	GRM2 GRM3	8.69e-06	2	103	2	20970439
Pubmed	Behavioural and biochemical responses to methamphetamine are differentially regulated by mGlu2 and mGlu3 metabotropic glutamate receptors in male mice.	GRM2 GRM3	8.69e-06	2	103	2	34217776
Pubmed	Memantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: exemplified by activity of an mGlu2/3 receptor agonist.	GRM2 GRM3	8.69e-06	2	103	2	21057775
Pubmed	Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes.	PCSK2 GZMA PAX1	8.97e-06	14	103	3	1354647
Pubmed	The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene expression.	ANKHD1 UBAP2L TNRC6A PUM1 MTDH	1.07e-05	97	103	5	37151849
Pubmed	Glycosylation and processing of the human immunodeficiency virus type 1 envelope protein.	GANC MAN1C1 CD4 MAN1A2	1.08e-05	46	103	4	2649653
Pubmed	Infectivities of human and other primate lentiviruses are activated by desialylation of the virion surface.	MAN1C1 CD4 MAN1A2	1.12e-05	15	103	3	8892864
Pubmed	Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells.	GANC MAN1C1 MAN1A2	1.66e-05	17	103	3	2355006
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	SCYL1 LMO7 UBAP2L TNRC6A PUM1 SNX9 MTDH	1.81e-05	274	103	7	34244482
Pubmed	Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.	FGR SNX9 FYN VAV1	2.37e-05	56	103	4	22745667
Pubmed	Graded heterogeneity of metabotropic signaling underlies a continuum of cell-intrinsic temporal responses in unipolar brush cells.	GRM2 GRM3	2.60e-05	3	103	2	34620856
Pubmed	Distribution of murine mannose receptor expression from early embryogenesis through to adulthood.	MRC2 ADGRE1	2.60e-05	3	103	2	9560474
Pubmed	Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.	ADAMTS3 ADAMTS14	2.60e-05	3	103	2	11741898
Pubmed	HIV glycoprotein gp120 inhibits TCR-CD3-mediated activation of fyn and lck.	CD4 FYN	2.60e-05	3	103	2	9043947
Pubmed	Frontline Science: Coincidental null mutation of Csf2rα in a colony of PI3Kγ-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection.	CSF2RA CSF2RB	2.60e-05	3	103	2	27468760
Pubmed	HIV envelope-directed signaling aberrancies and cell death of CD4+ T cells in the absence of TCR co-stimulation.	CD4 FYN	2.60e-05	3	103	2	8671590
Pubmed	The carboxy-terminal region of CD5 is required for c-CBL mediated TCR signaling downmodulation in thymocytes.	CD5 VAV1	2.60e-05	3	103	2	23376399
Pubmed	Vav guanine nucleotide exchange factors link hyperlipidemia and a prothrombotic state.	FYN VAV1	2.60e-05	3	103	2	21427288
Pubmed	Dissecting the dynamics of signaling events in the BMP, WNT, and NODAL cascade during self-organized fate patterning in human gastruloids.	WNT1 NODAL	2.60e-05	3	103	2	31613879
Pubmed	HIV infection in vitro enhances the activity of src-family protein tyrosine kinases.	CD4 FYN	2.60e-05	3	103	2	8883579
Pubmed	Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages.	WNT1 HTT	2.60e-05	3	103	2	18838463
Pubmed	Astrocytic PAR1 and mGluR2/3 control synaptic glutamate time course at hippocampal CA1 synapses.	GRM2 GRM3	2.60e-05	3	103	2	38864289
Pubmed	The cytoplasmic domain of granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha subunit is essential for both GM-CSF-mediated growth and differentiation.	CSF2RA CSF2RB	2.60e-05	3	103	2	9211889
Pubmed	Loss of surface antigens is a conserved feature of apoptotic lymphocytes from several mammalian species.	CD4 CD5	2.60e-05	3	103	2	21745657
Pubmed	Evaluation of 5-HT2A and mGlu2/3 receptors in postmortem prefrontal cortex of subjects with major depressive disorder: effect of antidepressant treatment.	GRM2 GRM3	2.60e-05	3	103	2	25150943
Pubmed	Granulocyte-macrophage colony-stimulating factor promotes glucose transport and blastomere viability in murine preimplantation embryos.	CSF2RA CSF2RB	2.60e-05	3	103	2	11259269
Pubmed	Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor.	CSF2RA CSF2RB	2.60e-05	3	103	2	1828890
Pubmed	Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.	TNRC6C TNRC6A	2.60e-05	3	103	2	31670606
Pubmed	A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase.	CD5 FYN	2.60e-05	3	103	2	21757751
Pubmed	The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues.	CSF2RA CSF2RB	2.60e-05	3	103	2	18469816
Pubmed	The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.	ADAMTS3 ADAMTS14	2.60e-05	3	103	2	25863161
Pubmed	Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesis.	MAN1C1 MAN1A2	2.60e-05	3	103	2	10915796
Pubmed	Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases.	CD5 FYN	2.60e-05	3	103	2	11298344
Pubmed	Pharmacogenetic analysis of the mGlu2/3 agonist LY2140023 monohydrate in the treatment of schizophrenia.	GRM2 GRM3	2.60e-05	3	103	2	21173788
Pubmed	Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics.	GRM2 GRM3	2.60e-05	3	103	2	24949866
Pubmed	Loss of striatal 90-kDa ribosomal S6 kinase (Rsk) is a key factor for motor, synaptic and transcription dysfunction in Huntington's disease.	RPS6KA3 HTT	2.60e-05	3	103	2	27063456
Pubmed	CD4-Lck through TCR and in the absence of Vav exchange factor induces Bax increase and mitochondrial damage.	CD4 VAV1	2.60e-05	3	103	2	12055221
Pubmed	Identification of primary structural features that define the differential actions of IL-3 and GM-CSF receptors.	CSF2RA CSF2RB	2.60e-05	3	103	2	12384414
Pubmed	Increased 90-kDa ribosomal S6 kinase (Rsk) activity is protective against mutant huntingtin toxicity.	RPS6KA3 HTT	2.60e-05	3	103	2	22041125
Pubmed	Expression of the receptor tyrosine kinase substrate genes eps8 and eps15 during mouse development.	EPS8 WNT1	2.60e-05	3	103	2	7566980
Pubmed	Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.	TNRC6C TNRC6A	2.60e-05	3	103	2	34108231
Pubmed	Binding of src-like kinases to the beta-subunit of the interleukin-3 receptor.	CSF2RB FYN	2.60e-05	3	103	2	9195918
Pubmed	The Ig-like domain of human GM-CSF receptor alpha plays a critical role in cytokine binding and receptor activation.	CSF2RA CSF2RB	2.60e-05	3	103	2	20078425
Pubmed	Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.	TNRC6C TNRC6A	2.60e-05	3	103	2	16880270
Pubmed	mGlu2 and mGlu3 Negative Allosteric Modulators Divergently Enhance Thalamocortical Transmission and Exert Rapid Antidepressant-like Effects.	GRM2 GRM3	2.60e-05	3	103	2	31735403
Pubmed	Association between interleukin-3 receptor alpha polymorphism and schizophrenia in the Chinese population.	CSF2RA CSF2RB	2.60e-05	3	103	2	18547720
Pubmed	Glycosylation inhibitors and neuraminidase enhance human immunodeficiency virus type 1 binding and neutralization by mannose-binding lectin.	GANC MAN1C1 MAN1A2	2.77e-05	20	103	3	12560567
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	CALR RPS6KA3 PHF8 KNOP1 LMO7 SCOC TNKS1BP1 HERC2 SNX9	3.05e-05	533	103	9	25544563
Pubmed	Influence of N-linked glycans in V4-V5 region of human immunodeficiency virus type 1 glycoprotein gp160 on induction of a virus-neutralizing humoral response.	GANC MAN1C1 MAN1A2	3.73e-05	22	103	3	8673525
Pubmed	Effect of various glycosidase treatments on the resistance of the HIV-1 envelope to degradation.	GANC MAN1C1 MAN1A2	3.73e-05	22	103	3	9109416
Interaction	CNOT2 interactions	TNRC6C ANKHD1 UBAP2L TNRC6A TNKS1BP1 PUM1 HTT CPEB1	2.95e-06	178	100	8	int:CNOT2
Interaction	CNOT10 interactions	TNRC6C UBAP2L TNRC6A TNKS1BP1 PUM1 HTT CPEB1	6.58e-06	141	100	7	int:CNOT10
Interaction	CLXN interactions	SCYL1 HERC2 SNX9	9.74e-06	9	100	3	int:CLXN
Interaction	CD5 interactions	CD4 CD5 FYN VAV1	1.42e-05	30	100	4	int:CD5
Interaction	ANKRD17 interactions	CAPN1 TNRC6C ANKHD1 UBAP2L TNRC6A TNKS1BP1 PUM1 CPEB1	1.70e-05	226	100	8	int:ANKRD17
Interaction	CNOT11 interactions	TNRC6C UBAP2L TNRC6A TNKS1BP1 PUM1 CPEB1	2.01e-05	112	100	6	int:CNOT11
Interaction	AGO2 interactions	CALR SCYL1 TNRC6C SKP2 KLHL29 UBAP2L TNRC6A PUM1 SNX9 HTT CPEB1	2.25e-05	472	100	11	int:AGO2
Interaction	CNOT8 interactions	TNRC6C TNRC6A PUM1 HTT CPEB1	3.34e-05	74	100	5	int:CNOT8
Interaction	C1QA interactions	CNTNAP3 APCS MRC2 USP40 HTT	4.05e-05	77	100	5	int:C1QA
Interaction	CNOT7 interactions	TNRC6C TNRC6A TNKS1BP1 PUM1 HTT CPEB1	7.04e-05	140	100	6	int:CNOT7
Interaction	CNOT3 interactions	TNRC6C UBAP2L TNRC6A TNKS1BP1 PUM1 HTT CPEB1	7.78e-05	207	100	7	int:CNOT3
Interaction	CPEB1 interactions	TNRC6C ANKHD1 UBAP2L TNRC6A PUM1 CPEB1	8.88e-05	146	100	6	int:CPEB1
Interaction	LRIG3 interactions	FBXO2 LMO7 MTDH CLEC12B	9.39e-05	48	100	4	int:LRIG3
Interaction	CNOT6L interactions	LRRC40 TNRC6C UBAP2L TNRC6A TNKS1BP1	1.00e-04	93	100	5	int:CNOT6L
Interaction	TAMALIN interactions	GRM2 GRM3 FYN	1.08e-04	19	100	3	int:TAMALIN
Interaction	CNOT1 interactions	SCYL1 TNRC6C UBAP2L TNRC6A TNKS1BP1 HERC2 PUM1 CPEB1	1.40e-04	305	100	8	int:CNOT1
Cytoband	20p11.2	PCSK2 PAX1	2.71e-04	11	103	2	20p11.2
GeneFamily	C-type lectin domain family	PLA2R1 CLEC20A MRC2 ASGR2 LY75 CLEC12B	4.57e-08	47	77	6	494
GeneFamily	Fibronectin type III domain containing	ROBO4 DSCAML1 CSF2RB ASTN1 OSMR EPHA3	6.17e-05	160	77	6	555
GeneFamily	Mannosidases alpha class 1	MAN1C1 MAN1A2	1.07e-04	4	77	2	1193
GeneFamily	ADAMTS like	PAPLN ADAMTSL2	3.71e-04	7	77	2	947
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM2 GRM3	4.93e-04	8	77	2	281
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	TNFSF14 CD4 CD5 CSF2RA CSF2RB MRC2 LY75	1.44e-03	394	77	7	471
GeneFamily	Aminopeptidases\|CD molecules	XPNPEP2 LAP3	2.34e-03	17	77	2	104
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS3 ADAMTS14	2.92e-03	19	77	2	50
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ROBO4 SPEG PAPLN DSCAML1	4.95e-03	161	77	4	593
GeneFamily	Ataxins\|Trinucleotide repeat containing	TNRC6C TNRC6A	5.04e-03	25	77	2	775
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	SSC4D LY75	5.87e-03	27	77	2	1253
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500	ADAMTS3 TNRC6C GRM3 KLHL29 MRC2 PAX1 OSMR	4.91e-06	142	100	7	gudmap_developingKidney_e13.5_podocyte cells_500_k1
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_500	ADAMTS3 TNRC6C GRM3 KLHL29 CSF2RB MRC2 APLNR ASTN1 PAX1 OSMR	3.64e-05	431	100	10	gudmap_developingKidney_e13.5_podocyte cells_500
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MGAM ADGRG3 F5 CSF2RA CSF2RB ASGR2 FGR ADGRE1 VAV1	7.23e-10	193	103	9	b044fca95f519ff2ceb378afe40a95911931a29e
ToppCell	PCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MGAM TNFSF14 F5 CSF2RA ASGR2 FGR ADGRE1 VAV1	1.47e-08	190	103	8	b7ce76931edc6734b80ddbb2fca23b098a8c1352
ToppCell	PCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MGAM ADGRG3 F5 CSF2RA CSF2RB ASGR2 FGR VAV1	1.47e-08	190	103	8	6a70d92cf66bdc9dade218b530f040f1581926f1
ToppCell	PCW_10-12-Hematologic_ErythroMegGranulo-Hem_Granulocytic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MGAM ADGRG3 F5 CSF2RA CSF2RB ASGR2 FGR VAV1	1.60e-08	192	103	8	0ba5729a890bfba5db567cd0eec7924cd1991ac3
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANKHD1 DLGAP3 CD4 CSF2RA ARFGAP1 FGR CLEC12B ZNF646	2.03e-08	198	103	8	c64238379798ae6b292cc1914d60548c88e652de
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MGAM ADGRG3 TNFSF14 F5 ASGR2 FGR VAV1	3.24e-07	192	103	7	d44f46352bac414b45cc749f7cbdc3a159bd7ae8
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte2_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	F5 CSF2RA CSF2RB ASGR2 FGR ADGRE1 VAV1	3.24e-07	192	103	7	6ac7ba0ef7d1b4f85dc12fa3f0ebaddc57f214a5
ToppCell	PCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_neutrophils_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADGRG3 CSF2RA CSF2RB ASGR2 FGR ADGRE1 VAV1	3.35e-07	193	103	7	888b11d7d66970931d1c33bea714659ca3cfe149
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CNTNAP3B MGAM ADGRG3 CNTNAP3 PLA2R1 CSF2RB	9.88e-07	142	103	6	191a13bba143ecdfc2bfd797c3ac191481388298
ToppCell	PBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CNTNAP3B MGAM ADGRG3 CNTNAP3 PLA2R1 CSF2RB	1.03e-06	143	103	6	b405dba9a83a99cc7b53ce71772bc52a0bbb0d4e
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F5 CSF2RA CSF2RB FGR ADGRE1 VAV1	1.84e-06	158	103	6	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F5 CSF2RA CSF2RB FGR ADGRE1 VAV1	1.84e-06	158	103	6	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DGKQ PHF8 KLHL29 VSTM4 HERC2 FYN	2.05e-06	161	103	6	5fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell	facs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFSF14 RPS6KA3 CAPN1 SSC4D CSF2RA FGR	2.28e-06	164	103	6	8e6dbddacd56a07769163813e3ebfad13302bb62
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Striatum / BrainAtlas - Mouse McCarroll V32	ADGRG3 F5 GZMA APLNR LY75	2.66e-06	94	103	5	858dda192747e71533736247bc9e135f763a8860
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Striatum / BrainAtlas - Mouse McCarroll V32	ADGRG3 F5 GZMA APLNR LY75	2.66e-06	94	103	5	901c4908d27a06c81853a02042cd331549e0e27d
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Striatum / BrainAtlas - Mouse McCarroll V32	ADGRG3 F5 GZMA APLNR LY75	2.66e-06	94	103	5	9d1dfd534871da30bc25a42e36bed9826f6127d8
ToppCell	severe_influenza-Neutrophil\|World / disease group, cell group and cell class (v2)	CNTNAP3B MGAM ADGRG3 CNTNAP3 F5 CSF2RB	3.22e-06	174	103	6	f9f07436b7d3f190800cd85d229f007032f391e1
ToppCell	metastatic_Brain-Endothelial_cells-Stalk-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	PCSK2 MAN1C1 SPEG ETV2 PAPLN NPTXR	3.32e-06	175	103	6	f6a6db992e803d36c866a91706b02f67e0fd3e09
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MPP1 VMO1 CD4 CSF2RA ASGR2 FGR	4.44e-06	184	103	6	ba260f8a2e6e510141a6b9c458eb0040acff0352
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PCSK2 ADGRG3 CNTNAP3 APCS F5 CSF2RB	4.44e-06	184	103	6	7ecdf2645e9378cf2f5ce4557f2cf100e6f184ba
ToppCell	PCW_10-12-Hematologic_ErythroMegGranulo\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MPP1 MGAM ADGRG3 F5 FGR VAV1	5.02e-06	188	103	6	adf9011ba8e3c6418fb68bf5c44b2e3b0ec7dafe
ToppCell	normal_Lymph_Node-B_lymphocytes-Undetermined\|B_lymphocytes / Location, Cell class and cell subclass	TNFSF14 F5 CD4 CD5 GZMA FYN	5.33e-06	190	103	6	85cf147f2baf2e575073b4edab57c7809475268a
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TNFSF14 CSF2RA ASGR2 FGR ADGRE1 VAV1	5.50e-06	191	103	6	79c83a710aa17fc06f286e4ea2011ed9e30e3bc6
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ROBO4 ADGRG3 APLNR FGR LY75	6.03e-06	111	103	5	9ba3590be8862c23b6e2917caed8bdbd9f9c2753
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ROBO4 ADGRG3 APLNR FGR LY75	6.03e-06	111	103	5	3e38efb22c47506ef2e2c1e19c79450e11d0ce56
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ROBO4 ADGRG3 APLNR FGR LY75	6.03e-06	111	103	5	cd84f2a9102a6eb63226ecde11d4ece54ff99b48
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-Monocytes\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	F5 CSF2RA CSF2RB ASGR2 FGR CLEC12B	6.19e-06	195	103	6	6d60a364b8c5c3384a430b858435f5cc542d80e3
ToppCell	LPS_IL1RA_TNF-Hematopoietic_Myeloid\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MGAM VMO1 CSF2RB FGR ADGRE1 VAV1	6.75e-06	198	103	6	c4a004f211f72f28aacbb512c6e075cbd049be53
ToppCell	NS-critical-d_16-33-Myeloid\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MPP1 ADGRG3 TNFSF14 CSF2RA CSF2RB FGR	6.75e-06	198	103	6	5602a78068ab6cccd4da1cc5566e68805820a295
ToppCell	LPS_only-Hematopoietic_Myeloid\|LPS_only / Treatment groups by lineage, cell group, cell type	MGAM VMO1 CSF2RB FGR ADGRE1 VAV1	6.95e-06	199	103	6	20523dee39a4c5f6423259920f108127b47525c4
ToppCell	LPS_only-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_only / Treatment groups by lineage, cell group, cell type	MGAM ADGRG3 CSF2RB FGR ADGRE1 VAV1	7.15e-06	200	103	6	3504aeba7b30cac9c428ba3871c072e2202752b4
ToppCell	LPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells-Neutrophils\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MGAM ADGRG3 CSF2RB FGR ADGRE1 VAV1	7.15e-06	200	103	6	fd1b6db3c62f5a205b769ba0e61433dae6285b67
ToppCell	LPS_IL1RA-Hematopoietic_Myeloid-Granulocytic_cells\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MGAM ADGRG3 CSF2RB FGR ADGRE1 VAV1	7.15e-06	200	103	6	0b7573ec4e9c67c7d11dd8f5011a70bade30e930
ToppCell	LPS_only-Hematopoietic_Myeloid-Granulocytic_cells\|LPS_only / Treatment groups by lineage, cell group, cell type	MGAM ADGRG3 CSF2RB FGR ADGRE1 VAV1	7.15e-06	200	103	6	c5afebbc16024c60e84a67be81c78b0bfb73ec68
ToppCell	Frontal_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ROBO4 ADGRG3 F5 APLNR LY75	1.35e-05	131	103	5	d5bc40cd585582856881081b7130dec3515b4ae0
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3\|Cerebellum / BrainAtlas - Mouse McCarroll V32	REM1 PLA2R1 SSC4D NODAL EPHA3	1.51e-05	134	103	5	8a3acf32cabc37b49d6488d43cdaae7cec79d119
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	REM1 PLA2R1 SSC4D NODAL EPHA3	1.51e-05	134	103	5	1fa13185a4dfb4563473184c0c4f449011d88631
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Acta2Rgs5.Rgs5_(Mural.Acta2Rgs5.Rgs5)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	REM1 PLA2R1 SSC4D NODAL EPHA3	1.51e-05	134	103	5	1ab99a22d0d7657f62f8ea7d96bb24e88de54fd4
ToppCell	T_cells-Treg_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	F5 CSF2RB SNX9 NODAL ZNF282	1.74e-05	138	103	5	35880e23ef317862891b54ac6a2265ca03b1d12a
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	REM1 PLA2R1 CD5 ADAMTS14	2.00e-05	69	103	4	a157b1582401cebd222343d94086dbea876140c2
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	REM1 PLA2R1 CD5 ADAMTS14	2.00e-05	69	103	4	cdd42abdd072aa438830d837ee857529269a81e0
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	CNTNAP3B LINC02875 ZNF365 CD4 CD5	2.28e-05	146	103	5	cffa91d76606f74553d81150adbb23b003746316
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD8-Trm_gut_CD8\|bone_marrow / Manually curated celltypes from each tissue	WNT1 DLGAP3 SLC2A4RG CPEB1 MASP2	2.68e-05	151	103	5	5eebdc7ad6af3cc0263e4d8c3516818305ac38f2
ToppCell	PND10-Immune-Immune_Myeloid-DC-cDC2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPS8 CSF2RA CSF2RB ASGR2 FGR	2.76e-05	152	103	5	27718e92715ddc80f28b457a5d6d6a3ac2b205d2
ToppCell	droplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l14\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPRASP1 ADGRG3 IFNLR1 CSF2RB CPEB1	2.76e-05	152	103	5	0fda8980b10ce16179dea92301db74d728f41794
ToppCell	droplet-Mammary_Gland-nan-3m-Myeloid\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	2.94e-05	154	103	5	12d3ecb0c4d814a91ac833fcb74db6b9dbc0a321
ToppCell	droplet-Mammary_Gland-nan-3m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	2.94e-05	154	103	5	64192a0f78021551886bbaf929916392bce451c0
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Matrix_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	ROBO4 KIF26A RPS6KA3 APLNR CLEC12B	2.94e-05	154	103	5	928f49839b046b90c2f942458f3e365ddc4e0bc9
ToppCell	droplet-Mammary_Gland-nan-3m-Myeloid-macrophage\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	2.94e-05	154	103	5	93ace0a42f3ea94605b13acd79659602b3a31b74
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 CSF2RA CSF2RB ASGR2 ADGRE1	3.23e-05	157	103	5	c8f516d3f5622202d3f8514f68614cd86ea3f667
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 CSF2RA CSF2RB ASGR2 ADGRE1	3.23e-05	157	103	5	4862a11ab8df27d26b4f1c1785e544a2d5b6db6e
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPS8 CSF2RA CSF2RB ASGR2 ADGRE1	3.23e-05	157	103	5	a0ec1628ce29841889f1d9d4ee9422921af7b0b5
ToppCell	PND10-Immune-Immune_Myeloid-DC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPS8 CSF2RA CSF2RB ASGR2 LY75	3.23e-05	157	103	5	ed387cf06d19e201a2a0dc4f3c796fcf8fa6637a
ToppCell	severe-CD4+_T_naive\|World / disease stage, cell group and cell class	ZNF77 VSTM4 DLGAP3 LMO7 ZNF197	3.23e-05	157	103	5	ccf9abe0b59e9ea728cec4bba1872ffe14c7385c
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPS8 MAN1C1 CSF2RB ASGR2 ADGRE1	3.33e-05	158	103	5	9a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPS8 MAN1C1 CSF2RB ASGR2 ADGRE1	3.33e-05	158	103	5	2438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCell	facs-MAT-Fat-24m-Myeloid-myeloid_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	F5 CSF2RA CSF2RB FGR ADGRE1	3.64e-05	161	103	5	65888250b8c1da6a8f9b5376e086a3769a1cbbd8
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPS8 CD4 CSF2RB ADGRE1 VAV1	3.75e-05	162	103	5	228e33678c7f963b3032a218333f206e5fff1292
ToppCell	facs-Lung-EPCAM-24m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEG CSF2RA NPTXR ADGRE1 VAV1	3.97e-05	164	103	5	4e0133a7f80cf6bd3d70f72ee26360df5f80ab32
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-macrophage\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	3.97e-05	164	103	5	8d089844896e84935eab705ebe54f125c4b6d9ca
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC40 ARMCX4 CD5 MRC2 GZMA	3.97e-05	164	103	5	d8ecb3de6e34f5f574449e3d2f26fa0b2b7e84e8
ToppCell	PND01-03-samps-Myeloid-Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	MPP1 CSF2RA CSF2RB ADGRE1 LY75	3.97e-05	164	103	5	49733a9d3d95f05056b5b01916060ff20a8de3cf
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEG CSF2RA NPTXR ADGRE1 VAV1	3.97e-05	164	103	5	4ab1a7d5379a633c3f61af1c8c2df93b6961d9cf
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	3.97e-05	164	103	5	17fb1421476ba44999b1165f2576514f74c1f882
ToppCell	facs-Kidney-nan-24m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.09e-05	165	103	5	a359dda24c2c10b7b8df902a7c4c2ebf27b041f3
ToppCell	facs-Kidney-nan-24m-Myeloid-macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.09e-05	165	103	5	1d5880aa49e6e6e95bde14a40fbe6e40b71c6d22
ToppCell	facs-Kidney-nan-24m-Myeloid\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.09e-05	165	103	5	cdc09cbfd6eaeb8e436d83bbca7146bde3b3f01e
ToppCell	facs-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM TNFSF14 F5 CSF2RB FGR	4.21e-05	166	103	5	3195035445d35d820f5e00dd03b029730478b024
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.21e-05	166	103	5	82fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCell	facs-Lung-3m-Hematologic-myeloid-neutrophil\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MGAM TNFSF14 F5 CSF2RB FGR	4.21e-05	166	103	5	6b6ecd70264b6bfbd8a3a378c965702829e2ecf1
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.21e-05	166	103	5	0d03926452414f232c77fd15d5f48d148f9fca3b
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm_gut_CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	EPS8 TNFSF14 WNT1 SLC2A4RG FYN	4.33e-05	167	103	5	69de7d7fc69d699eab03dfea84fdb54263aa5a47
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.33e-05	167	103	5	7f9eedf68a800159c5642e04dd9569ae58109bd5
ToppCell	facs-Heart-LA-3m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC4D CD4 CD5 GZMA ZNF646	4.46e-05	168	103	5	16c3313c4186fa327d71215f8eebc31fc12ff1c0
ToppCell	facs-Heart-LA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC4D CD4 CD5 GZMA ZNF646	4.46e-05	168	103	5	24d1e0a05cda09ee3b80208d75cb2b601023f3bf
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPS8 TNFSF14 PGAP6 ADGRE1 SNX9	4.46e-05	168	103	5	93b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCell	CTRL-Myeloid-Monocyte\|CTRL / Disease state, Lineage and Cell class	MGAM TNFSF14 F5 ASGR2 FYN	4.46e-05	168	103	5	13dca90c7b811e4d5e8fa44f5e892e29be9787a6
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	F5 CSF2RA CSF2RB FGR ADGRE1	4.46e-05	168	103	5	ba9ddd403ee6d6af2fe56dffbd419764bfb703e4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	F5 KLHL29 PLA2R1 FYN CPEB1	4.46e-05	168	103	5	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	E18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EPS8 TNFSF14 PGAP6 ADGRE1 SNX9	4.46e-05	168	103	5	e393553208617a023f1646169c892a87c95db3f5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	F5 KLHL29 PLA2R1 FYN CPEB1	4.46e-05	168	103	5	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	F5 CSF2RA CSF2RB FGR ADGRE1	4.46e-05	168	103	5	af4c35c0d3f030cef8397c35fa498a71112bb16b
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	F5 KLHL29 PLA2R1 FYN CPEB1	4.46e-05	168	103	5	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	facs-Heart-LA-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SSC4D CD4 CD5 GZMA ZNF646	4.46e-05	168	103	5	b952af95a68888adedd03b1b60836d18524611ab
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.46e-05	168	103	5	ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l12-15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TNFSF14 CSF2RA CSF2RB ADGRE1 VAV1	4.58e-05	169	103	5	f2f2ac2c9991c7cbc62e24a633e58f98b6274e6b
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPEG PLA2R1 MRC2 ASTN1 EPHA3	4.58e-05	169	103	5	87116c33c5ca8cb1862e103e5607b1df4d264569
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB ASGR2 FGR VAV1	4.58e-05	169	103	5	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	CNTNAP3B MGAM ADGRG3 CNTNAP3 CSF2RB	4.58e-05	169	103	5	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB ASGR2 FGR VAV1	4.58e-05	169	103	5	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB ASGR2 FGR VAV1	4.58e-05	169	103	5	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPEG CD4 SCAMP5 ASGR2 ADGRE1	4.71e-05	170	103	5	f664c7559e383b37845c123e41a3be316d869ba0
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.71e-05	170	103	5	e4856e768d0088e42fbdb8e6039f5bc3daa0afdb
ToppCell	droplet-Lung-1m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPEG CD4 SCAMP5 ASGR2 ADGRE1	4.71e-05	170	103	5	0272eb1487c2545d4aa06f5d1cd77f823e1441e9
ToppCell	facs-Trachea-nan-18m-Myeloid-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.71e-05	170	103	5	774b0c1b453e19651f9481dc6bcabac538c5acb7
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-NK_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRG3 TNFSF14 GZMA FGR FYN	4.85e-05	171	103	5	f16cb64b8844c2668922c786888efaa9f873afcc
ToppCell	CTRL-Myeloid-Monocyte\|Myeloid / Disease state, Lineage and Cell class	MGAM TNFSF14 F5 ASGR2 FYN	4.85e-05	171	103	5	bfa01571516a0b24476ae06cb07f56c5579dbd70
ToppCell	facs-Trachea-nan-18m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF2RA CSF2RB FGR ADGRE1 VAV1	4.85e-05	171	103	5	9d496a6edac9663791cda684188d49895246f6fe
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	MGAM ADGRG3 TNFSF14 CNTNAP3 CSF2RB	4.98e-05	172	103	5	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
Drug	sodium chloride	MGAM GANC CALR MAN1C1 APCS LAP3 FBXO2 PLA2R1 CD4 MAN1A2 CSF2RB MRC2 ASGR2 LY75 NODAL MASP2	1.28e-06	865	101	16	CID000000206
Drug	BM21.1290	CD4 HTT	1.95e-05	2	101	2	CID000064140
Drug	NSC-210825	MGAM CALR	1.95e-05	2	101	2	CID000427282
Drug	C75; Up 200; 10uM; MCF7; HT_HG-U133A	APCS GRM3 F5 FBXO2 MRC2 CPEB1 MASP2	2.82e-05	197	101	7	6423_UP
Drug	Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A	MAN1C1 SPEG GRM3 CSF2RB MRC2 ZNF197 ZNF646	2.92e-05	198	101	7	3842_UP
Drug	AC1NRATE	MGAM GANC MAN1C1 CD4 MAN1A2	3.43e-05	83	101	5	CID005288086
Drug	heptaminol AMP amidate	CD4 CD5	5.83e-05	3	101	2	CID000162816
Drug	7-deoxy-6-epi-castanospermine	MGAM GANC	5.83e-05	3	101	2	CID000125391
Drug	AC1NUR2V	MGAM GANC	5.83e-05	3	101	2	CID005489114
Drug	isospaglumic acid	GRM2 GRM3	5.83e-05	3	101	2	ctd:C027172
Drug	callyspongynic acid	MGAM GANC	5.83e-05	3	101	2	CID000636783
Drug	IPG7F	MGAM GANC	5.83e-05	3	101	2	CID003083273
Drug	Pradimicin Q	MGAM GANC	5.83e-05	3	101	2	CID000073572
Drug	3-nitro-4-(6-aminohexylamido)phenylboronic acid	MGAM GANC	5.83e-05	3	101	2	CID000133488
Drug	AC1L4EIS	CD4 CD5	5.83e-05	3	101	2	CID000155562
Drug	magnesium; zinc	MGAM LAP3	5.83e-05	3	101	2	CID011457656
Drug	LY 379268	GRM2 GRM3	5.83e-05	3	101	2	ctd:C118218
Drug	hydroxylamine sulfate	MGAM CALR	5.83e-05	3	101	2	CID000024846
Drug	AC1L1GT5	MGAM GANC CALR MAN1C1 MAN1A2	6.57e-05	95	101	5	CID000003829
Drug	Man(9)GlcNAc	MGAM GANC MAN1C1 MAN1A2	7.77e-05	51	101	4	CID003081561
Drug	Croton Oil	TNFSF14 CSF2RA CSF2RB OSMR	9.73e-05	54	101	4	ctd:D003436
Drug	VTCs	MGAM REM1 XPNPEP2 SLC2A4RG	9.73e-05	54	101	4	CID000006413
Drug	myrciaphenone B	MGAM GANC	1.16e-04	4	101	2	CID000183139
Drug	Ro 18-5364	MGAM CALR	1.16e-04	4	101	2	CID000127803
Drug	NSC277293	MGAM GANC	1.16e-04	4	101	2	CID000321973
Drug	gamma-glutamyl-2-naphthylamide	MGAM GANC	1.16e-04	4	101	2	CID000164706
Drug	atalaphyllidine	MGAM GANC	1.16e-04	4	101	2	CID005479542
Drug	LY 341495	GRM2 GRM3	1.16e-04	4	101	2	ctd:C114624
Drug	Tc17	CD4 CD5	1.16e-04	4	101	2	CID006445219
Drug	glycovir	MGAM GANC	1.16e-04	4	101	2	CID000060807
Drug	thiochroman-4-one	MGAM GANC	1.16e-04	4	101	2	CID000019048
Drug	2-deoxymaltose	MGAM GANC	1.16e-04	4	101	2	CID003081508
Drug	AC1L3RZ0	MGAM GANC	1.16e-04	4	101	2	CID000145814
Drug	aluminum isopropoxide	CALR SKP2	1.16e-04	4	101	2	CID000011143
Drug	wollastonite	MGAM ZNF77 TNRC6A	1.23e-04	22	101	3	CID000026370
Disease	Pulmonary Alveolar Proteinosis	CSF2RA CSF2RB	3.27e-05	3	98	2	C0034050
Disease	Pulmonary alveolar proteinosis, congenital	CSF2RA CSF2RB	3.27e-05	3	98	2	C2931035
Disease	Addicted to cocaine	GRM2 GRM3	3.27e-05	3	98	2	C0858355
Disease	secretory phospholipase A2 receptor measurement	PLA2R1 LY75	3.27e-05	3	98	2	EFO_0802043
Disease	pulmonary alveolar proteinosis (implicated_via_orthology)	CSF2RA CSF2RB	1.08e-04	5	98	2	DOID:12120 (implicated_via_orthology)
Disease	colorectal cancer (implicated_via_orthology)	FGR SNX9 FYN	1.35e-04	30	98	3	DOID:9256 (implicated_via_orthology)
Disease	pulmonary alveolar proteinosis (is_implicated_in)	CSF2RA CSF2RB	1.62e-04	6	98	2	DOID:12120 (is_implicated_in)
Disease	autosomal recessive intellectual developmental disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3	3.02e-04	8	98	2	DOID:0060308 (implicated_via_orthology)
Disease	Colorectal Carcinoma	PCSK2 CALR F5 DSCAML1 VSTM4 LMO7 NODAL MTDH EPHA3	5.55e-04	702	98	9	C0009402
Disease	sphingomyelin 18:1 measurement	APLNR TNKS1BP1	8.32e-04	13	98	2	EFO_0010394
Disease	alcohol consumption measurement	MGAM KIF26A PAPLN DPP3 GRM3 KLHL29 SPTBN5 DLGAP3 TNRC6A SCAF11 HTT EPHA3	8.46e-04	1242	98	12	EFO_0007878
Disease	urokinase plasminogen activator surface receptor measurement	ASGR2 LY75	9.68e-04	14	98	2	EFO_0010932
Disease	autism spectrum disorder (implicated_via_orthology)	CNTNAP3B CNTNAP3 DSCAML1 SCAMP5	1.68e-03	152	98	4	DOID:0060041 (implicated_via_orthology)
Disease	Alcoholic Intoxication, Chronic	GRM2 GRM3 DSCAML1 ASTN1 FYN	2.03e-03	268	98	5	C0001973
Disease	Psychoses, Drug	CALR GRM2	2.20e-03	21	98	2	C0033937
Disease	portal hypertension (biomarker_via_orthology)	F5 CPEB1	2.42e-03	22	98	2	DOID:10762 (biomarker_via_orthology)
Disease	Epilepsy, Benign Psychomotor, Childhood	GRM2 GRM3	2.64e-03	23	98	2	C0393672
Disease	Epilepsy, Lateral Temporal	GRM2 GRM3	2.64e-03	23	98	2	C0393682
Disease	Uncinate Epilepsy	GRM2 GRM3	2.64e-03	23	98	2	C0014558
Disease	Epilepsy, Temporal Lobe	GRM2 GRM3	2.64e-03	23	98	2	C0014556

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDLSSSGWNSWVFGI	nan	96	A4D1N5
SWFWNGEEAGNSFST	BHLHB9	121	Q6PI77
WVGRTNETHTSWGGS	CNTNAP3	701	Q9BZ76
FNTWIGLTDSDGSWK	ASGR2	231	P07307
NASFTWVASDGWGAL	GRM2	286	Q14416
ANASFTWVASDGWGA	GRM3	291	Q14832
AGWGRTHNSASWSDT	GZMA	151	P12544
SQSWGRSSKQWEDPS	CD5	61	P06127
SWGSGADLWGSDSDT	DGKQ	821	P52824
VFWDVTKGTTGDWSS	ADGRG3	216	Q86Y34
TERRSSDSWEVWGSA	ARFGAP1	356	Q8N6T3
SDSWEVWGSASTNRN	ARFGAP1	361	Q8N6T3
VEWTGAWSDSSSEWN	CAPN1	301	P07384
AWTGAENQASGGSWA	ARMCX4	1211	Q5H9R4
WTGAENQASEGSWAG	ARMCX4	1266	Q5H9R4
SWAGAGSQASGESWA	ARMCX4	1671	Q5H9R4
SSLWCSGTGDVIEDW	ASTN1	996	O14525
EQTYGQDGGWSSWTK	ADAMTS14	546	Q8WXS8
NWSSWEEVSVQDSTG	OSMR	131	Q99650
ESAQSSRLPWETWGS	RFX5	491	P48382
VSSEWAWEVGLGVSS	APLNR	191	P35414
GSGATGVFTNSSWLW	LAP3	401	P28838
EGDWWEARSLSSGKT	FGR	111	P09769
PSEGSSAWDSSDRSW	IFNLR1	376	Q8IU57
SSSAAWLRQQGATDW	NUDT22	96	Q9BRQ3
DGWIRVQWDTGSTNS	HERC2	1901	O95714
NRRGHTQSADWWSFG	RPS6KA3	241	P51812
SSGRWAGHWLGDNTA	MGAM	2411	O43451
GWFGARVTNSSVWVE	FBXO2	281	Q9UK22
GAVWTGDNTAEWSNL	GANC	581	Q8TET4
LATWEATWSEGSKSS	LMO7	1296	Q8WWI1
SVDQSWSWLDGSEVT	LY75	1606	O60449
NDLDTSGGWQWSDNS	MRC2	301	Q9UBG0
SNSLEGGTDATAFWW	ADAMTSL2	36	Q86TH1
TGEQIQSWYRSGETW	DPP3	481	Q9NY33
TRKWTGTQFGQWDTA	KNOP1	351	Q1ED39
WAGSSHGSSISSWLS	KIF26A	1101	Q9ULI4
GWRGWSCTDNSTAQT	PGAP6	526	Q9HCN3
GDSVSSNSAAWNWIR	IGHV6-1	46	A0A0B4J1U7
WTTRDGLWSAYQDGE	NPTXR	386	O95502
IFLGDQWRDSAWGTS	PUM1	166	Q14671
QWRDSAWGTSDHSVS	PUM1	171	Q14671
AWRVSWEGAAAAAAG	PAX1	11	P15863
DGNWGSWTKFGSCSR	ADAMTS3	551	O15072
LGWTSRTQFEETWAT	HTT	2456	P42858
TSRTGYNGIWSEWSE	CSF2RB	416	P32927
GTWAWQGLRANSSGE	DSCAML1	1521	Q8TD84
EGDWWEARSLTTGET	FYN	116	P06241
SADGRAWFPSESSWQ	LINC02875	146	Q86X59
GRHQAKSTGWWSSDD	DLGAP3	251	O95886
KSTGWWSSDDNLDSD	DLGAP3	256	O95886
QFLDGDGWTSRWIES	CALR	26	P27797
GELWWQAERASSSKS	CD4	236	P01730
TTFRTTGDWLNGVWT	EPHA3	911	P29320
VSFKSGNWGWATAGS	MAN1C1	306	Q9NR34
GNWGWATAGSSSILA	MAN1C1	311	Q9NR34
DSETERWFVGGIVSW	MASP2	641	O00187
TGDANTNGKDWGRSW	MTDH	326	Q86UE4
RNWGWASAGSSILAE	MAN1A2	321	O60476
GWDRPWSTQDSDSSA	CPEB1	106	Q9BZB8
NWWQGRVEGSSKESA	MPP1	201	Q00013
SRVAAWSAWAADQGD	EPS8	231	Q12929
SWSRAQAAGSNTSWD	ETV2	141	O00321
SRAQVASENGGRWAW	GRAMD2A	251	Q8IUY3
RGSWGTVCDDSWDTS	DMBT1	381	Q9UGM3
RGSWGTVCDDSWDTN	DMBT1	751	Q9UGM3
PADRSGWTSASSWAV	SCAF11	1136	Q99590
GSFSKAQEEWTTGAW	SCAMP5	181	Q8TAC9
GASWQDETRWSDSSV	C4orf51	31	C9J302
WVGRTNETHTSWGGS	CNTNAP3B	701	Q96NU0
WSSWSEAIEFGSDDG	CSF2RA	306	P15509
SFGATERWWEQTDLT	LRRC40	71	Q9H9A6
WSSESSDSEGSWEAL	REM1	66	O75628
GSWLWATEESNIDGT	GPRASP1	721	Q5JY77
WSASKSGNWESSEGW	SNX9	111	Q9Y5X1
AWSAGGGDWADSSSV	TNRC6C	591	Q9HCJ0
GSGWDADSNRSGSGW	TNRC6C	616	Q9HCJ0
AASWAGWAVTGVSSL	SCYL1	566	Q96KG9
SDWSSWEAEGSWEQG	SCYL1	691	Q96KG9
TSWVGWGSQGTEAAQ	F5	16	P12259
QLGGSTLLWEAESSW	NODAL	206	Q96S42
FSSQDWRASGWDGMG	SCOC	6	Q9UIL1
HVVESQSGSWGEWSE	VMO1	96	Q7Z5L0
AGSWEWSDRTPVVSS	PLA2R1	746	Q13018
EEQAESWWRALGSTA	SPTBN5	3626	Q9NRC6
DSQWLADTWRSTSGS	ROBO4	521	Q8WZ75
VSWSTDVKGGRWTSF	ADGRE1	551	Q14246
WSFGVNAVSEGLSGW	ANKHD1	2401	Q8IWZ3
LSWDSSGRSWFWEDG	CLEC12B	206	Q2HXU8
RWSSGSTFTALEWGQ	CLEC20A	81	Q6ZU45
SSWEAGSQGNWGLTS	LINC01561	41	Q8N1V8
TWGWDSSKTSELLSG	SKP2	21	Q13309
GSDSWSIFGENWRFD	ZNF77	76	Q15935
DDTWKWGTSFQGSSS	ZNF197	21	O14709
DDGTSAWRTATEEWG	UBAP2L	231	Q14157
SVTGTSEEQVSWWGS	SPEG	176	Q15772
SWESSSGIAEFWING	APCS	116	P02743
SSNSGDWGWDLASDQ	SLC2A4RG	151	Q9NR83
TSSSRVWWDSSFLGG	TNFSF14	191	O43557
SPASDSRGQWWAAQE	PAPLN	566	O95428
SSATREDWAWQTDPS	SSC4D	301	Q8WTU2
WWEGRNTSTNEIGWF	VAV1	636	P15498
VDGTWGSSAARWSDQ	TNKS1BP1	1521	Q9C0C2
SWGQRLGSSEGWENQ	ZNF646	126	O15015
SGRWWGIVNVASSTN	WNT1	31	P04628
TSSLQAWWTGGQDRS	PHF8	776	Q9UPP1
AWWTGGQDRSSGSSS	PHF8	781	Q9UPP1
WRWQSGNSSDLETTS	ZNF365	76	Q70YC4
RNKWTAWSNGSSATE	VSTM4	136	Q8IW00
WDGTTDITRTVHWGT	XPNPEP2	456	O43895
WGRVWRATSSQGASG	USP40	961	Q9NVE5
SQGWSVSASDNWGET	TNRC6A	846	Q8NDV7
QGLGLDSGSWSWAQA	ZNF282	16	Q9UDV7
WDRREWSVNGTHGTT	KLHL29	16	Q96CT2
TTHTWGEDARGTWTL	PCSK2	556	P16519