Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of telomere capping	ERCC1 RTEL1 AURKB	1.39e-05	27	36	3	GO:1904353
GeneOntologyBiologicalProcess	negative regulation of telomere maintenance in response to DNA damage	ERCC1 RTEL1	2.95e-05	5	36	2	GO:1904506
GeneOntologyBiologicalProcess	negative regulation of chromosome organization	ERCC1 INCENP RTEL1 AURKB	3.55e-05	107	36	4	GO:2001251
GeneOntologyBiologicalProcess	telomere capping	ERCC1 RTEL1 AURKB	4.97e-05	41	36	3	GO:0016233
GeneOntologyBiologicalProcess	regulation of t-circle formation	ERCC1 RTEL1	6.19e-05	7	36	2	GO:1904429
GeneOntologyBiologicalProcess	positive regulation of attachment of mitotic spindle microtubules to kinetochore	INCENP AURKB	8.24e-05	8	36	2	GO:1902425
GeneOntologyBiologicalProcess	regulation of attachment of mitotic spindle microtubules to kinetochore	INCENP AURKB	1.32e-04	10	36	2	GO:1902423
GeneOntologyBiologicalProcess	mitotic spindle midzone assembly	INCENP AURKB	1.61e-04	11	36	2	GO:0051256
GeneOntologyBiologicalProcess	mitotic spindle elongation	INCENP AURKB	1.93e-04	12	36	2	GO:0000022
GeneOntologyBiologicalProcess	positive regulation of attachment of spindle microtubules to kinetochore	INCENP AURKB	1.93e-04	12	36	2	GO:0051987
GeneOntologyBiologicalProcess	positive regulation of mitotic cell cycle spindle assembly checkpoint	INCENP AURKB	1.93e-04	12	36	2	GO:0090267
GeneOntologyBiologicalProcess	positive regulation of mitotic cytokinesis	INCENP AURKB	2.28e-04	13	36	2	GO:1903490
GeneOntologyBiologicalProcess	positive regulation of spindle checkpoint	INCENP AURKB	2.28e-04	13	36	2	GO:0090232
GeneOntologyBiologicalProcess	spindle midzone assembly	INCENP AURKB	2.66e-04	14	36	2	GO:0051255
GeneOntologyBiologicalProcess	spindle elongation	INCENP AURKB	2.66e-04	14	36	2	GO:0051231
GeneOntologyBiologicalProcess	positive regulation of telomere maintenance	ERCC1 RTEL1 AURKB	2.68e-04	72	36	3	GO:0032206
GeneOntologyBiologicalProcess	formation of extrachromosomal circular DNA	ERCC1 RTEL1	3.07e-04	15	36	2	GO:0001325
GeneOntologyBiologicalProcess	telomere maintenance via telomere trimming	ERCC1 RTEL1	3.07e-04	15	36	2	GO:0090737
GeneOntologyBiologicalProcess	t-circle formation	ERCC1 RTEL1	3.07e-04	15	36	2	GO:0090656
GeneOntologyBiologicalProcess	regulation of metaphase plate congression	INCENP AURKB	3.07e-04	15	36	2	GO:0090235
GeneOntologyBiologicalProcess	regulation of mitotic cytokinesis	INCENP AURKB	3.50e-04	16	36	2	GO:1902412
GeneOntologyBiologicalProcess	positive regulation of telomere capping	RTEL1 AURKB	3.96e-04	17	36	2	GO:1904355
GeneOntologyBiologicalProcess	positive regulation of cell cycle checkpoint	INCENP AURKB	4.97e-04	19	36	2	GO:1901978
GeneOntologyBiologicalProcess	regulation of telomere maintenance in response to DNA damage	ERCC1 RTEL1	5.52e-04	20	36	2	GO:1904505
GeneOntologyBiologicalProcess	positive regulation of mitotic sister chromatid separation	INCENP AURKB	5.52e-04	20	36	2	GO:1901970
GeneOntologyBiologicalProcess	mitotic cytokinesis	INCENP IQGAP2 AURKB	6.05e-04	95	36	3	GO:0000281
GeneOntologyBiologicalProcess	regulation of mitotic spindle checkpoint	INCENP AURKB	7.32e-04	23	36	2	GO:1903504
GeneOntologyBiologicalProcess	regulation of mitotic cell cycle spindle assembly checkpoint	INCENP AURKB	7.32e-04	23	36	2	GO:0090266
GeneOntologyBiologicalProcess	regulation of attachment of spindle microtubules to kinetochore	INCENP AURKB	7.98e-04	24	36	2	GO:0051988
GeneOntologyBiologicalProcess	regulation of spindle checkpoint	INCENP AURKB	9.38e-04	26	36	2	GO:0090231
GeneOntologyBiologicalProcess	regulation of telomere maintenance	ERCC1 RTEL1 AURKB	9.77e-04	112	36	3	GO:0032204
GeneOntologyBiologicalProcess	positive regulation of chromosome organization	ERCC1 RTEL1 AURKB	1.00e-03	113	36	3	GO:2001252
GeneOntologyBiologicalProcess	attachment of mitotic spindle microtubules to kinetochore	INCENP AURKB	1.01e-03	27	36	2	GO:0051315
GeneOntologyBiologicalProcess	regulation of chromosome organization	ERCC1 INCENP RTEL1 AURKB	1.15e-03	266	36	4	GO:0033044
GeneOntologyBiologicalProcess	positive regulation of chromosome segregation	INCENP AURKB	1.17e-03	29	36	2	GO:0051984
GeneOntologyBiologicalProcess	response to X-ray	LRP2 ERCC1	1.25e-03	30	36	2	GO:0010165
GeneOntologyBiologicalProcess	positive regulation of chromosome separation	INCENP AURKB	1.33e-03	31	36	2	GO:1905820
GeneOntologyBiologicalProcess	cytoskeleton-dependent cytokinesis	INCENP IQGAP2 AURKB	1.40e-03	127	36	3	GO:0061640
GeneOntologyBiologicalProcess	telomere maintenance in response to DNA damage	ERCC1 RTEL1	1.70e-03	35	36	2	GO:0043247
GeneOntologyBiologicalProcess	positive regulation of telomere maintenance via telomere lengthening	RTEL1 AURKB	2.11e-03	39	36	2	GO:1904358
GeneOntologyCellularComponent	chromocenter	TRIM66 INCENP AURKB	4.09e-06	18	37	3	GO:0010369
GeneOntologyCellularComponent	chromosome passenger complex	INCENP AURKB	4.55e-05	6	37	2	GO:0032133
Domain	DNA/RNA_helicase_DEAH_CS	CHD1 RTEL1	2.07e-03	35	36	2	IPR002464
Domain	DEAH_ATP_HELICASE	CHD1 RTEL1	2.43e-03	38	36	2	PS00690
Domain	RNaseH-like_dom	PRPF8 POLE	7.81e-03	69	36	2	IPR012337
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	TRMT1L PRPF8 INCENP IQGAP2 VIRMA MED12 POLE AURKB	1.09e-06	759	37	8	35915203
Pubmed	Centromere localization of INCENP-Aurora B is sufficient to support spindle checkpoint function.	INCENP AURKB	1.10e-06	2	37	2	20372054
Pubmed	Relocation of the chromosomal passenger complex prevents mitotic checkpoint engagement at anaphase.	INCENP AURKB	1.10e-06	2	37	2	20619651
Pubmed	Switching of INCENP paralogs controls transitions in mitotic chromosomal passenger complex functions.	INCENP AURKB	1.10e-06	2	37	2	31306061
Pubmed	Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres.	INCENP AURKB	3.30e-06	3	37	2	17322402
Pubmed	Overexpression of an Aurora-C kinase-deficient mutant disrupts the Aurora-B/INCENP complex and induces polyploidy.	INCENP AURKB	3.30e-06	3	37	2	15917996
Pubmed	The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes.	INCENP AURKB	3.30e-06	3	37	2	21123620
Pubmed	Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis.	INCENP AURKB	3.30e-06	3	37	2	16386730
Pubmed	Molecular distinctions between Aurora A and B: a single residue change transforms Aurora A into correctly localized and functional Aurora B.	INCENP AURKB	3.30e-06	3	37	2	19494039
Pubmed	Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo.	INCENP AURKB	3.30e-06	3	37	2	14610074
Pubmed	Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis.	INCENP AURKB	3.30e-06	3	37	2	11050385
Pubmed	Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis.	INCENP AURKB	3.30e-06	3	37	2	12925766
Pubmed	Cell death in leukemia: passenger protein regulation by topoisomerase inhibitors.	INCENP AURKB	6.60e-06	4	37	2	17681274
Pubmed	INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization.	INCENP AURKB	6.60e-06	4	37	2	19951914
Pubmed	Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together.	INCENP AURKB	6.60e-06	4	37	2	17956729
Pubmed	Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex.	INCENP AURKB	6.60e-06	4	37	2	27332895
Pubmed	Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C.	INCENP AURKB	6.60e-06	4	37	2	15316025
Pubmed	v-Src causes delocalization of Mklp1, Aurora B, and INCENP from the spindle midzone during cytokinesis failure.	INCENP AURKB	6.60e-06	4	37	2	23562843
Pubmed	Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay.	INCENP AURKB	6.60e-06	4	37	2	21051298
Pubmed	EVI5 protein associates with the INCENP-aurora B kinase-survivin chromosomal passenger complex and is involved in the completion of cytokinesis.	INCENP AURKB	6.60e-06	4	37	2	16764853
Pubmed	Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP.	INCENP AURKB	6.60e-06	4	37	2	16571674
Pubmed	Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody.	INCENP AURKB	6.60e-06	4	37	2	16239925
Pubmed	INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis.	INCENP AURKB	6.60e-06	4	37	2	11516652
Pubmed	Control of apoptosis and mitotic spindle checkpoint by survivin.	INCENP AURKB	6.60e-06	4	37	2	9859993
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	PRR12 ERCC1 TRMT1L TCF12 MED12 POLE	7.80e-06	453	37	6	29656893
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CHD1 TRMT1L PRPF8 INCENP VIRMA MED12 POLE AURKB	9.25e-06	1014	37	8	32416067
Pubmed	A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.	TCF12 LYL1	1.10e-05	5	37	2	23812588
Pubmed	Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle.	INCENP AURKB	1.10e-05	5	37	2	15249581
Pubmed	Regulation of aurora B kinase by the lipid raft protein flotillin-1.	INCENP AURKB	1.10e-05	5	37	2	20430883
Pubmed	Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis.	INCENP AURKB	1.10e-05	5	37	2	12584241
Pubmed	Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cells.	INCENP AURKB	1.10e-05	5	37	2	21346195
Pubmed	A common mechanism for recruiting the Rrm3 and RTEL1 accessory helicases to the eukaryotic replisome.	RTEL1 POLE	1.10e-05	5	37	2	39039288
Pubmed	Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells.	INCENP AURKB	1.10e-05	5	37	2	18773538
Pubmed	The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function.	INCENP AURKB	1.10e-05	5	37	2	17099693
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF462 PRR12 TRIM66 NPHP4 RTEL1 MED12	1.26e-05	493	37	6	15368895
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	PRR12 PRPF8 MED12	1.33e-05	43	37	3	26487511
Pubmed	EB1 promotes Aurora-B kinase activity through blocking its inactivation by protein phosphatase 2A.	INCENP AURKB	1.65e-05	6	37	2	18477699
Pubmed	RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.	ERCC1 RTEL1	1.65e-05	6	37	2	22579284
Pubmed	A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function.	INCENP AURKB	1.65e-05	6	37	2	19357306
Pubmed	Phosphorylation of the CPC by Cdk1 promotes chromosome bi-orientation.	INCENP AURKB	2.30e-05	7	37	2	20739936
Pubmed	Two histone marks establish the inner centromere and chromosome bi-orientation.	INCENP AURKB	2.30e-05	7	37	2	20929775
Pubmed	Sequential assembly of centromeric proteins in male mouse meiosis.	INCENP AURKB	3.07e-05	8	37	2	19283064
Pubmed	Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.	INCENP AURKB	3.95e-05	9	37	2	21613325
Pubmed	RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.	INCENP AURKB	4.93e-05	10	37	2	18946085
Pubmed	Mitotic kinase Aurora-B is regulated by SUMO-2/3 conjugation/deconjugation during mitosis.	INCENP AURKB	4.93e-05	10	37	2	21554500
Pubmed	IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway.	RTEL1 POLE	4.93e-05	10	37	2	23585563
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	CHD1 PRPF8 INCENP VIRMA MED12 POLE	6.06e-05	653	37	6	22586326
Pubmed	The Cul3-KLHL21 E3 ubiquitin ligase targets aurora B to midzone microtubules in anaphase and is required for cytokinesis.	INCENP AURKB	7.22e-05	12	37	2	19995937
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 ZNF462 LRP2 PRR12 MED12	7.78e-05	418	37	5	34709266
Pubmed	Differential interactions of Id proteins with basic-helix-loop-helix transcription factors.	TCF12 LYL1	8.53e-05	13	37	2	9242638
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ZNF462 CHD1 ERCC1 RTEL1	9.05e-05	222	37	4	37071664
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF462 INCENP AURKB	9.60e-05	83	37	3	20562864
Pubmed	Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation.	INCENP AURKB	9.94e-05	14	37	2	21875947
Pubmed	SLX4 interacts with RTEL1 to prevent transcription-mediated DNA replication perturbations.	ERCC1 RTEL1	1.15e-04	15	37	2	32398829
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	ZNF462 CHD1 TRMT1L POLE AURKB	1.33e-04	469	37	5	27634302
Pubmed	LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis.	TCF12 LYL1	1.67e-04	18	37	2	19497860
Pubmed	TIF1gamma controls erythroid cell fate by regulating transcription elongation.	TCF12 LYL1	1.67e-04	18	37	2	20603019
Pubmed	Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.	ERCC1 LYL1	1.86e-04	19	37	2	8432525
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	PRR12 CHD1 TCF12	2.15e-04	109	37	3	33554859
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	ZNF462 PRR12 CHD1 TRMT1L PRPF8 AURKB	2.50e-04	847	37	6	35850772
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	TRMT1L TCF12 CPOX PRPF8 IQGAP2 POLE	2.66e-04	857	37	6	25609649
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	ERCC1 TRMT1L PRPF8 POLE AURKB	3.61e-04	582	37	5	20467437
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	CHD1 PRPF8 INCENP AURKB	4.11e-04	330	37	4	33301849
Pubmed	Control of developmentally primed erythroid genes by combinatorial co-repressor actions.	TCF12 LYL1	4.70e-04	30	37	2	26593974
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 ZNF462 PRR12 MED12	5.18e-04	351	37	4	38297188
Pubmed	HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages.	INCENP AURKB	5.35e-04	32	37	2	27114546
Pubmed	Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.	TRIM66 DLGAP1 ZNF654	5.38e-04	149	37	3	25231870
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	PRR12 PRPF8 NPHP4 VIRMA	5.75e-04	361	37	4	30344098
Pubmed	SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair.	ERCC1 RTEL1	6.05e-04	34	37	2	31495888
Pubmed	Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.	LRP2 NPHP4	6.78e-04	36	37	2	33737325
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	TRMT1L IQGAP2 VIRMA POLE	8.43e-04	400	37	4	35013556
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	PRPF8 IQGAP2 VIRMA POLE AURKB	8.54e-04	704	37	5	29955894
Pubmed	Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.	MOB1B AURKB	9.23e-04	42	37	2	29632206
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	PRR12 TCF12 NPHP4	9.92e-04	184	37	3	32908313
Interaction	TTC27 interactions	TRIM66 PRPF8 NPHP4 VIRMA	3.88e-05	107	36	4	int:TTC27
Interaction	CIAO2B interactions	TRIM66 RTEL1 VIRMA POLE	3.88e-05	107	36	4	int:CIAO2B
Interaction	VLDLR interactions	TRIM66 FHIP2A VIRMA	4.58e-05	39	36	3	int:VLDLR
Interaction	CENPA interactions	ZNF462 CHD1 INCENP VIRMA POLE AURKB	4.99e-05	377	36	6	int:CENPA
Interaction	SLX4 interactions	ZNF462 CHD1 ERCC1 TCF12 INCENP RTEL1 VIRMA	5.84e-05	572	36	7	int:SLX4
Interaction	CSMD1 interactions	TRIM66 VIRMA	6.48e-05	7	36	2	int:CSMD1
Interaction	ZSWIM5 interactions	NPHP4 VIRMA	6.48e-05	7	36	2	int:ZSWIM5
Interaction	KLHL21 interactions	ZNF462 VIRMA AURKB	7.54e-05	46	36	3	int:KLHL21
Interaction	RALGAPA2 interactions	NPHP4 VIRMA AURKB	8.57e-05	48	36	3	int:RALGAPA2
Interaction	UTP14C interactions	LRP2 VIRMA AURKB	9.68e-05	50	36	3	int:UTP14C
Interaction	BAG2 interactions	TRIM66 PRPF8 NPHP4 VIRMA MED12 POLE AURKB	9.87e-05	622	36	7	int:BAG2
Interaction	PTGES3 interactions	PRPF8 NPHP4 RTEL1 VIRMA POLE AURKB	1.13e-04	437	36	6	int:PTGES3
Interaction	SNRNP40 interactions	ZNF462 CHD1 TRMT1L TCF12 PRPF8 VIRMA MED12	1.15e-04	637	36	7	int:SNRNP40
Interaction	RCN2 interactions	ZNF462 TRIM66 NPHP4 VIRMA AURKB	1.37e-04	282	36	5	int:RCN2
Cytoband	17p13.3	PRPF8 SGSM2	2.32e-03	88	37	2	17p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	PRPF8 SGSM2 AURKB	2.73e-03	346	37	3	chr17p13
Cytoband	Ensembl 112 genes in cytogenetic band chr20q13	GTSF1L RTEL1 PMEPA1	4.75e-03	422	37	3	chr20q13
GeneFamily	Baculoviral IAP repeat containing\|Chromosomal passenger complex	INCENP AURKB	6.27e-06	4	19	2	1338
GeneFamily	Basic helix-loop-helix proteins	TCF12 LYL1	5.86e-03	110	19	2	420
Coexpression	RB_P107_DN.V1_UP	TMEM45B INCENP CES5A POLE	3.36e-05	130	37	4	M2802
Coexpression	OHASHI_AURKB_TARGETS	INCENP AURKB	5.40e-05	8	37	2	M10867
Coexpression	GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP	CPOX INCENP POLE AURKB	1.38e-04	187	37	4	M2984
Coexpression	FURUKAWA_DUSP6_TARGETS_PCI35_DN	RTEL1 PMEPA1 AURKB	1.50e-04	73	37	3	M7339
Coexpression	GSE12366_GC_VS_NAIVE_BCELL_DN	PRR12 CHD1 LYL1 PMEPA1	1.62e-04	195	37	4	M3170
Coexpression	THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP	DLGAP1 CHD1 GNL1	1.70e-04	76	37	3	M2117
Coexpression	GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	TCF12 CES5A IQGAP2 MED12	1.75e-04	199	37	4	M9498
Coexpression	GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP	LRP2 PRR12 LYL1 MOB1B	1.75e-04	199	37	4	M9366
Coexpression	GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN	ERCC1 TCF12 IQGAP2 ZNF654	1.78e-04	200	37	4	M7178
Coexpression	GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_DN	CHD1 CES5A VIRMA F12	1.78e-04	200	37	4	M5715
Coexpression	GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP	CPOX INCENP POLE AURKB	1.78e-04	200	37	4	M3580
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 NUDT7 IQGAP2 RTEL1 AURKB	3.22e-07	174	37	5	6987fe7959afce347282f632abc16d800ccab7c4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NUDT7 OMD INCENP AURKB	1.02e-05	164	37	4	25758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NUDT7 OMD INCENP AURKB	1.02e-05	164	37	4	1642a67c66eeb77a218e7814e3cfe517d9822955
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 IQGAP2 NPHP4 F12	1.13e-05	168	37	4	b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF462 INCENP POLE AURKB	1.13e-05	168	37	4	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 IQGAP2 NPHP4 F12	1.13e-05	168	37	4	b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OMD INCENP POLE AURKB	1.29e-05	174	37	4	c988471207ba06195bc3e41056435e8c31c20bbe
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-late_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF12 INCENP NPHP4 AURKB	1.68e-05	186	37	4	ec6d0c29e196e374baa96dd3d506f489c959e77e
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TCF12 INCENP NPHP4 AURKB	1.68e-05	186	37	4	3993f1ef8a33b8a75dfd3db8d4845b5afbb0bb3d
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-FOXM1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	C2orf69 INCENP POLE AURKB	2.19e-05	199	37	4	98575fcce726589e93fbb4df1aab03e57cb56076
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRMT1L TMEM45B F12	1.48e-04	124	37	3	d88bce8a4f023d5b617b2e8e372a94bd1248d20d
ToppCell	LPS_only-Endothelial-Endothelial-FOXM1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	INCENP POLE AURKB	1.86e-04	134	37	3	4d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCell	droplet-Liver-hepatocytes-3m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHYH NUDT7 F12	2.45e-04	147	37	3	00619115b9a1ec2b967c2992043b41974ece63c4
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRERF1 LYL1 AURKB	2.91e-04	156	37	3	f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 PHYH TMEM45B	3.08e-04	159	37	3	0f6ff73410fd6a6f97a53cb865952963a73848dd
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DLGAP1 INCENP AURKB	3.31e-04	163	37	3	e4077e587895c85bc806be05ff5d451088e39468
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF462 TRIM66 RTEL1	3.37e-04	164	37	3	b895674ed2df87db8fbfb30b7e31620945588491
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP IQGAP2 AURKB	3.43e-04	165	37	3	26c750f10f6401752e2e63d91dc844c81b29d735
ToppCell	ICU-SEP-Lymphocyte-T_NK-dnT\|ICU-SEP / Disease, Lineage and Cell Type	GTSF1L NUDT7 CPOX	3.49e-04	166	37	3	96d92316cee20b722fe782db9dafcceb8f2c220b
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP IQGAP2 AURKB	3.56e-04	167	37	3	d21635df8b74189e3309eaf435af381fbe412574
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP IQGAP2 AURKB	3.62e-04	168	37	3	b7cd33f5da4f37b9384fc3bd3ca01fbc790accfc
ToppCell	droplet-Lung-30m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPHP4 POLE AURKB	3.68e-04	169	37	3	822e5b6c1e55e196e6d2a38bf183fd220c45703e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	INCENP POLE AURKB	3.68e-04	169	37	3	b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP IQGAP2 AURKB	3.75e-04	170	37	3	a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	TRIM66 INCENP AURKB	3.75e-04	170	37	3	5319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP IQGAP2 AURKB	3.75e-04	170	37	3	b04e2f84024baaae9b4ff19bdac8c69afdb92a76
ToppCell	COVID-19-lung-RBC\|lung / Disease (COVID-19 only), tissue and cell type	CPOX LYL1 MOB1B	3.81e-04	171	37	3	0e8d63c8fbccdda4f1ef00de00667a50464b104b
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TRIM66 GNL1 F12	3.88e-04	172	37	3	80b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPOX LYL1 MOB1B	3.88e-04	172	37	3	cc1a45a35f78063b2a777ae905f70f894fbcb22f
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Red_blood_cells-RBC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPOX LYL1 MOB1B	3.88e-04	172	37	3	30c57f5ca2326e8d890d9aac8096c64e5b51a24f
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	INCENP POLE AURKB	3.88e-04	172	37	3	7c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCell	droplet-Lung-nan-18m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP NPHP4 AURKB	3.88e-04	172	37	3	e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP NPHP4 PMEPA1	3.94e-04	173	37	3	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP NPHP4 PMEPA1	3.94e-04	173	37	3	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C2orf69 INCENP AURKB	3.94e-04	173	37	3	12c6875f881cb0fbff09d753b53c1cce7a95527f
ToppCell	COVID-19-lung-RBC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CPOX LYL1 MOB1B	4.08e-04	175	37	3	4c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP IQGAP2 AURKB	4.08e-04	175	37	3	ae7e0448ffd11b8908d0f6d99ff737faf5eca4bf
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRERF1 POLE AURKB	4.08e-04	175	37	3	73f25bd54309aed1480ddc44bdab518b17e71f92
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TRIM66 INCENP AURKB	4.15e-04	176	37	3	8813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell	droplet-Lung-18m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP NPHP4 AURKB	4.15e-04	176	37	3	b17317ac41d3215db55a38cbd3366c0947f7a2a3
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	DLGAP1 IQGAP2 SGSM2	4.15e-04	176	37	3	792f414f5092aba14260b8e16378e793a822498e
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	OMD INCENP AURKB	4.22e-04	177	37	3	4197cf2b1e743230c821f422836fa5991b155a52
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	INCENP POLE AURKB	4.22e-04	177	37	3	8a74f5e72de605774111057bd87a7e7e4a6385cd
ToppCell	Dividing_Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	INCENP RTEL1 AURKB	4.29e-04	178	37	3	1893fadac2ec3d5de0a641e57b7b2f962012a9ba
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM45B PMEPA1 F12	4.36e-04	179	37	3	bc93883c2094f2e5bfed79facd4994a23968d875
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM45B PMEPA1 F12	4.36e-04	179	37	3	0cef6d2eab2015cac0dd340532b24bfec9707330
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TRIM66 INCENP AURKB	4.36e-04	179	37	3	e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell	facs-Brain_Myeloid-Cortex-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM45B PMEPA1 F12	4.36e-04	179	37	3	bb2410b3934fcc53396b96b48e0d9843df159b89
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM45B PMEPA1 F12	4.36e-04	179	37	3	065241799cea30da62cb3b6f2f1970bd1b0f4e2b
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 NUDT7 IQGAP2	4.43e-04	180	37	3	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 DLGAP1 NUDT7	4.43e-04	180	37	3	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 DLGAP1 NUDT7	4.43e-04	180	37	3	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 DLGAP1 NUDT7	4.43e-04	180	37	3	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 NUDT7 IQGAP2	4.43e-04	180	37	3	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TRIM66 INCENP AURKB	4.43e-04	180	37	3	b35a8c6169f4b548b912af005e92ae7c6596f376
ToppCell	P15-Endothelial-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	INCENP NPHP4 AURKB	4.50e-04	181	37	3	0c5bc1660b8fc1e905ab4230202862de5be46ebd
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CPOX LYL1 MOB1B	4.50e-04	181	37	3	14c2dd946e89ba578711c2d25935b6b3d319b701
ToppCell	wk_20-22-Hematologic-Meg-ery\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 MOB1B	4.50e-04	181	37	3	d0637f9ccec5dba4997520b27287989522e04f96
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPOX LYL1 MOB1B	4.50e-04	181	37	3	577bf37a6594fad01251d2c66d8ccda8e949b6cf
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Red_blood_cells-RBC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPOX LYL1 MOB1B	4.50e-04	181	37	3	f5dc7a650afe8837cb424981e50ad2c8b18c7c32
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CPOX LYL1 MOB1B	4.50e-04	181	37	3	9dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CPOX LYL1 MOB1B	4.50e-04	181	37	3	c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCell	P15-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	INCENP NPHP4 AURKB	4.50e-04	181	37	3	f83565f09dd971c5cad2704a4a86bca0accd955e
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CPOX LYL1 MOB1B	4.50e-04	181	37	3	fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCell	droplet-Lung-LUNG-30m-Lymphocytic-Proliferating_NK\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHP4 POLE AURKB	4.57e-04	182	37	3	0370b395ceb9d4d66f80cf60dd8c28ac60af5c7b
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 MOB1B	4.57e-04	182	37	3	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZNF462 LYL1 RTEL1	4.57e-04	182	37	3	4cd5eb13f78f4f377932c50ac2acb4ac0cd14c12
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP POLE AURKB	4.57e-04	182	37	3	bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 NUDT7 IQGAP2	4.57e-04	182	37	3	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INCENP POLE AURKB	4.57e-04	182	37	3	0fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CPOX LYL1 MOB1B	4.65e-04	183	37	3	b52d7683dc6652766e814ebe935c264ecd610c4b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GTSF1L LRP2 TMEM45B	4.65e-04	183	37	3	18040d0653286071df959513c63d94b555a5d00a
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CPOX LYL1 MOB1B	4.65e-04	183	37	3	1db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CPOX LYL1 MOB1B	4.65e-04	183	37	3	1d77d8d8c8f78f43dd8864e76f294ee66d4942c2
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 MOB1B	4.65e-04	183	37	3	5470e5ac3439cfc96acd2202f6b1e386779a6637
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GTSF1L LRP2 TMEM45B	4.65e-04	183	37	3	6ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP POLE AURKB	4.72e-04	184	37	3	1edefa2a049d7e22d0bdb1ea3d7ef1c8d6ae0fe3
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-Proliferating_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP POLE AURKB	4.72e-04	184	37	3	8578c50eaa8ce1cefc0228185c66c8e25f4bfc32
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Lymphocytic-T_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LYL1 INCENP AURKB	4.72e-04	184	37	3	185b49630da61cbf45c0926d1b992943296d2a54
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP POLE AURKB	4.79e-04	185	37	3	89b85ce8026dc80c1bd9f76dfe16401c173b7946
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP POLE AURKB	4.79e-04	185	37	3	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPOX LYL1 MOB1B	4.79e-04	185	37	3	c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-Proliferating_T_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP POLE AURKB	4.79e-04	185	37	3	0e0f043ad6d2a62cd47ce39911ad81feab4a4d7e
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	LRP2 INCENP AURKB	4.79e-04	185	37	3	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	Immune-enucleated_erythrocyte\|World / Lineage, Cell type, age group and donor	CPOX LYL1 MOB1B	4.87e-04	186	37	3	f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 LRP2 DLGAP1	4.87e-04	186	37	3	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 IQGAP2	4.87e-04	186	37	3	294839944266407c40ef86e1d3e0fce4652b70ff
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_reticulocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 MOB1B	4.87e-04	186	37	3	bf8ca7135c05d772aa3f5960b419a13aef3936ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 LRP2 DLGAP1	4.95e-04	187	37	3	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TRERF1 INCENP IQGAP2	4.95e-04	187	37	3	8c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCell	droplet-Marrow-nan-24m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPOX INCENP AURKB	4.95e-04	187	37	3	99724aa3dbdcb073ea3bfe80cc825ecae5495db8
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Lymphocytic\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LYL1 INCENP AURKB	4.95e-04	187	37	3	e53471c3e146a6f54788d81ecc469aba55b051bb
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Lymphocytic-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LYL1 INCENP AURKB	4.95e-04	187	37	3	3d7d51fbadb20dc884d0b3c0d61b80f022b19d09
ToppCell	droplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	INCENP POLE AURKB	5.02e-04	188	37	3	0ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPOX LYL1 MOB1B	5.02e-04	188	37	3	f81099b5b3f1f85a28445bc663efcf73baccb2be
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 IQGAP2	5.02e-04	188	37	3	5d6faf45a9c0794b0c30b0a0601c10afbb8aa9ed
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 IQGAP2	5.02e-04	188	37	3	29d804232d974a8c0029300345b287005b09bade
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells-RBC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPOX LYL1 MOB1B	5.02e-04	188	37	3	05b3ade422beeb3db73d350fe192c21bfcfef188
ToppCell	PCW_05-06-Hematologic_ErythroMegGranulo\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CPOX LYL1 IQGAP2	5.02e-04	188	37	3	a0873783f0a2cd852563c05a275dddc72905ced2
ToppCell	Fibroblast-E_(Early_Fibroblastic_progenitor)\|World / shred on cell class and cell subclass (v4)	INCENP PMEPA1 AURKB	5.02e-04	188	37	3	be3db9768364568f44e32ae6b3bf99e49b0978bb
Disease	prostate cancer (implicated_via_orthology)	CHD1 PRPF8 POLE	9.65e-06	33	37	3	DOID:10283 (implicated_via_orthology)
Disease	transient cerebral ischemia (is_implicated_in)	ERCC1 F12	8.35e-05	11	37	2	DOID:224 (is_implicated_in)
Disease	Craniosynostosis	ZNF462 TCF12	2.87e-04	20	37	2	C0010278
Disease	Global developmental delay	ZNF462 PRR12 FHIP2A	6.22e-04	133	37	3	C0557874
Disease	response to simvastatin, myopathy	NUDT7 ERCC1	1.22e-03	41	37	2	EFO_0004145, GO_1903491

Protein segments in the cluster

Peptide	Gene	Start	Entry
HHVLYFPGDVQNYHE	C2orf69	101	Q8N8R5
YRHLGHYNHQRFPSI	CFAP46	271	Q8IYW2
PVEHHPADHPYYTQR	DLGAP1	36	O14490
NYLFHEHQLYGPFLL	CHD1	521	O14646
IHQYYHPPNLLELFG	INCENP	856	Q9NQS7
YDPHHRIPLSRFQYH	GTSF1L	11	Q9H1H1
LSLRYHNLHPDYIHG	ERCC1	141	P07992
HIPPQYLHLVANEYF	CES5A	376	Q6NT32
YGNLHSHDRLSYPPH	TCF12	266	Q99081
YDQPRHVQYATHFPI	MED12	726	Q93074
YFHQHYPQLHVVLFT	GNL1	241	P36915
NTTHRPFDIHVYHPY	LRP2	3446	P98164
FRVYAHIYHQHFDPV	MOB1B	156	Q7L9L4
PGSIRHIYLYHHAQA	POLE	1481	Q07864
YFLHPQVHDQHYVTR	NUDT7	151	P0C024
FNEPLYFHTSLNHPH	NPHP4	91	O75161
HRFQPTYPYLQHEID	PMEPA1	131	Q969W9
ALHYHPHPFLNSVYI	LYL1	101	P12980
LFPHPHIHEYLLDPY	FHIP2A	666	Q5W0V3
NPHAPTIHFNYRYFE	CPOX	251	P36551
PLHYHHLTYIRVDQN	OMD	326	Q99983
RHPLHQDLHYFPFRP	PHYH	171	O14832
PCHFPFQYHRQLYHK	F12	46	P00748
HNLLQGFYQFVRPHH	RTEL1	946	Q9NZ71
HPPFYYNIHRHSIKG	TRMT1L	631	Q7Z2T5
PQHYQHYLATPRMHH	RNF165	181	Q6ZSG1
VVHEIRNYPYPQLHF	RNF165	206	Q6ZSG1
VDPAHAQHYQDVLYH	IQGAP2	486	Q13576
YVFRIIYPGHRHEHN	SGSM2	416	O43147
HRQAYAAPHPLQSYA	PRR12	46	Q9ULL5
HLHHPNILRLYNYFY	AURKB	131	Q96GD4
FPYLYNNLPHHVHLT	PRPF8	316	Q6P2Q9
LFYYHVHNRPPLDQH	TMEM45B	131	Q96B21
HFIDHLNRHSYPNVY	ZNF654	801	Q8IZM8
GLLLHYQRRHPEHYV	ZNF462	1326	Q96JM2
FHEPVSPLARHYYQI	TRIM66	1066	O15016
DDPYPVLFRYLHSHH	VIRMA	666	Q69YN4
YHRDPHQYTPEQAHT	TRERF1	351	Q96PN7
QVRLQYIHPAFFHHF	KLHL38	221	Q2WGJ6