Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionolfactory receptor activity

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

1.43e-154316518GO:0004984
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

OR8I2 OR5M9 P2RX1 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 TNFRSF10D ACVR1B OR10G9 OR10G8 OR10S1 IL1RAP OR4K3 OR10J1 PLXNA2 NOTCH2 EPHA3 OR10G7 OR10G4

2.44e-1413536526GO:0004888
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR8I2 OR5M9 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

2.80e-118846519GO:0004930
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ANO2 P2RX1 ATP11B KCNJ10 KCNK2 ANO7 ATP13A5 LRRC8B ATP1A4 ATP2B1 PLP2 SLC36A2 RYR2

1.35e-067936513GO:0015075
GeneOntologyMolecularFunctiontransporter activity

ANO2 P2RX1 ATP11B KCNJ10 KCNK2 SLC44A2 ANO7 ATP13A5 LRRC8B ATP1A4 ATP10A ATP2B1 PLP2 SLC36A2 RYR2

1.26e-0512896515GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

ANO2 P2RX1 ATP11B KCNJ10 KCNK2 SLC44A2 ANO7 ATP13A5 LRRC8B ATP1A4 ATP2B1 PLP2 SLC36A2 RYR2

2.09e-0511806514GO:0022857
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ANO2 ATP11B ANO7 ATP10A

2.28e-0551654GO:0140303
GeneOntologyMolecularFunctionsuramin binding

P2RX1 RYR2

3.12e-053652GO:0043924
GeneOntologyMolecularFunctionodorant binding

OR8I2 OR5M9 OR4E1 OR5T2 OR10J1

5.85e-05127655GO:0005549
GeneOntologyMolecularFunctionphospholipid transporter activity

ANO2 ATP11B ANO7 ATP10A

9.92e-0574654GO:0005548
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP13A5 ATP1A4 ATP2B1

2.18e-0436653GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP13A5 ATP1A4 ATP2B1

2.18e-0436653GO:0015662
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

ANO2 P2RX1 KCNJ10 ANO7 RYR2

4.14e-04193655GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

ANO2 P2RX1 KCNJ10 ANO7 RYR2

4.54e-04197655GO:0022834
GeneOntologyMolecularFunctionmonoatomic ion channel activity

ANO2 P2RX1 KCNJ10 KCNK2 ANO7 LRRC8B RYR2

7.14e-04459657GO:0005216
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

ANO2 P2RX1 KCNJ10 KCNK2 ANO7 ATP1A4 ATP2B1 SLC36A2 RYR2

7.43e-04758659GO:0015318
GeneOntologyMolecularFunctiongated channel activity

ANO2 P2RX1 KCNJ10 KCNK2 ANO7 RYR2

7.54e-04334656GO:0022836
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP11B ATP10A

9.26e-0414652GO:0140333
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP13A5 ATP1A4 ATP2B1

1.09e-0362653GO:0019829
GeneOntologyMolecularFunctionfloppase activity

ATP11B ATP10A

1.22e-0316652GO:0140328
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

P2RX1 KCNJ10 KCNK2 ATP13A5 ATP1A4 ATP2B1 SLC36A2 RYR2

1.36e-03664658GO:0008324
GeneOntologyMolecularFunctionflippase activity

ATP11B ATP10A

1.37e-0317652GO:0140327
GeneOntologyMolecularFunctionchannel activity

ANO2 P2RX1 KCNJ10 KCNK2 ANO7 LRRC8B RYR2

1.56e-03525657GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

ANO2 P2RX1 KCNJ10 KCNK2 ANO7 LRRC8B RYR2

1.57e-03526657GO:0022803
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

ANO2 ANO7

1.91e-0320652GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

ANO2 ANO7

1.91e-0320652GO:0005229
GeneOntologyMolecularFunctionphospholipid scramblase activity

ANO2 ANO7

2.53e-0323652GO:0017128
GeneOntologyMolecularFunctionATP hydrolysis activity

DHX36 ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

3.09e-03441656GO:0016887
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP11B ATP10A

3.73e-0328652GO:0140326
GeneOntologyMolecularFunctionATP-dependent activity

DHX36 ATP11B DNAH17 ATP13A5 ATP1A4 ATP10A ATP2B1

3.73e-03614657GO:0140657
GeneOntologyMolecularFunctionlipid transporter activity

ANO2 ATP11B ANO7 ATP10A

3.82e-03196654GO:0005319
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

P2RX1 KCNJ10 KCNK2 ATP1A4 ATP2B1 RYR2

4.00e-03465656GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

P2RX1 KCNJ10 KCNK2 ATP1A4 ATP2B1 SLC36A2 RYR2

4.19e-03627657GO:0022890
GeneOntologyMolecularFunctionligand-gated calcium channel activity

P2RX1 RYR2

4.57e-0331652GO:0099604
GeneOntologyMolecularFunctionmonoatomic anion channel activity

ANO2 ANO7 LRRC8B

4.62e-03103653GO:0005253
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP13A5 ATP1A4 ATP2B1

5.41e-03109653GO:0042626
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

8.55e-164326518GO:0050911
GeneOntologyBiologicalProcessdetection of chemical stimulus

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 RYR2 OR10G7 OR10G4

1.49e-155246519GO:0009593
GeneOntologyBiologicalProcesssensory perception of smell

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

3.07e-154656518GO:0007608
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

6.35e-154856518GO:0050907
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

OR8I2 EYS OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

1.00e-145826519GO:0050906
GeneOntologyBiologicalProcessdetection of stimulus

OR8I2 EYS OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 RYR2 OR10G7 OR10G4

3.80e-147226520GO:0051606
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

5.01e-145476518GO:0007606
GeneOntologyBiologicalProcesssensory perception

OR8I2 EYS OR5M9 OR4K17 OR4A5 OR2AP1 KCNJ10 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

5.27e-1110726520GO:0007600
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

OR8I2 OR5M9 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 KCNK2 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

5.25e-0913956520GO:0007186
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ANO2 P2RX1 ATP11B KCNJ10 KCNK2 ANO7 ATP13A5 LRRC8B ATP1A4 ATP10A ATP2B1 PLP2 MRLN SLC36A2 RYR2

1.45e-0611156515GO:0034220
GeneOntologyBiologicalProcessmonoatomic ion transport

ANO2 P2RX1 ATP11B KCNJ10 KCNK2 ANO7 ATP13A5 LRRC8B ATP1A4 ATP10A ATP2B1 PLP2 MRLN SLC36A2 RYR2

1.83e-0513746515GO:0006811
GeneOntologyBiologicalProcessorganophosphate ester transport

ATP11B CD47 ANO7 LRRC8B ATP10A

1.59e-04162655GO:0015748
GeneOntologyCellularComponentendoplasmic reticulum membrane

SCAP COPB1 BSG VAMP7 OR4E1 KCNK2 LRRC8B RNF175 ATP10A PLP2 MRLN SLC36A2 NOTCH2 RYR2

3.48e-0512936514GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

SCAP COPB1 BSG VAMP7 OR4E1 KCNK2 LRRC8B RNF175 ATP10A PLP2 MRLN SLC36A2 NOTCH2 RYR2

3.66e-0512996514GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

SCAP COPB1 BSG VAMP7 OR4E1 KCNK2 LRRC8B RNF175 ATP10A PLP2 MRLN SLC36A2 NOTCH2 RYR2

4.62e-0513276514GO:0042175
GeneOntologyCellularComponentsecretory granule membrane

P2RX1 ATP11B COPB1 BSG VAMP7 SLC44A2 CD47

7.14e-05329657GO:0030667
GeneOntologyCellularComponenttransporter complex

ANO2 ATP11B KCNJ10 KCNK2 LRRC8B ATP1A4 ATP10A RYR2

2.95e-04550658GO:1990351
GeneOntologyCellularComponentimmunological synapse

NPTN CD81 ATP2B1

4.77e-0449653GO:0001772
GeneOntologyCellularComponentcell surface

NPTN P2RX1 TRHR VAMP7 CST8 KCNK2 CD47 ADAM29 TNFRSF10D ACVR1B NOTCH2

5.79e-0411116511GO:0009986
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP11B ATP10A

8.46e-0414652GO:1990531
GeneOntologyCellularComponentpresynapse

NPTN ANO2 P2RX1 KCNJ10 VAMP7 KCNK2 CD47 ATP2B1 EPHA3

1.61e-03886659GO:0098793
GeneOntologyCellularComponentpresynaptic active zone membrane

NPTN P2RX1 ATP2B1

1.85e-0378653GO:0048787
GeneOntologyCellularComponentcytoplasmic vesicle membrane

SCAP P2RX1 ATP11B COPB1 BSG VAMP7 SLC44A2 CD47 ATP13A5 ATP2B1 SLC36A2

2.16e-0313076511GO:0030659
GeneOntologyCellularComponentvesicle membrane

SCAP P2RX1 ATP11B COPB1 BSG VAMP7 SLC44A2 CD47 ATP13A5 ATP2B1 SLC36A2

2.41e-0313256511GO:0012506
GeneOntologyCellularComponentastrocyte projection

KCNJ10 KCNK2

2.73e-0325652GO:0097449
GeneOntologyCellularComponentspecific granule membrane

P2RX1 SLC44A2 CD47

2.87e-0391653GO:0035579
GeneOntologyCellularComponentnon-motile cilium

ANO2 EYS BSG ATP1A4

3.25e-03196654GO:0097730
DomainOlfact_rcpt

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

1.21e-123936015IPR000725
DomainGPCR_Rhodpsn_7TM

OR8I2 OR5M9 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

2.17e-106706016IPR017452
Domain7tm_1

OR8I2 OR5M9 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

2.52e-106776016PF00001
DomainG_PROTEIN_RECEP_F1_1

OR8I2 OR5M9 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

3.00e-106856016PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8I2 OR5M9 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

3.40e-106916016PS50262
DomainGPCR_Rhodpsn

OR8I2 OR5M9 TRHR OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

3.47e-106926016IPR000276
Domain-

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

5.44e-08326053.40.1110.10
Domain-

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

5.44e-08326052.70.150.10
DomainATPase_P-typ_cyto_domN

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

8.70e-0835605IPR023299
DomainP_typ_ATPase

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

1.01e-0736605IPR001757
DomainATPase_P-typ_P_site

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

1.01e-0736605IPR018303
DomainATPASE_E1_E2

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

1.01e-0736605PS00154
DomainATPase_P-typ_transduc_dom_A

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

1.16e-0737605IPR008250
DomainE1-E2_ATPase

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

1.16e-0737605PF00122
DomainHAD-like_dom

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

5.42e-0679605IPR023214
DomainBasigin

NPTN BSG

1.01e-052602IPR009151
DomainCation_ATPase_N

ATP13A5 ATP1A4 ATP2B1

2.49e-0518603PF00690
DomainCation_ATPase_N

ATP13A5 ATP1A4 ATP2B1

2.49e-0518603SM00831
DomainATPase_P-typ_cation-transptr_N

ATP13A5 ATP1A4 ATP2B1

2.94e-0519603IPR004014
DomainAnoct_dimer

ANO2 ANO7

2.11e-047602PF16178
DomainAnoct_dimer

ANO2 ANO7

2.11e-047602IPR032394
DomainAnoctamin

ANO2 ANO7

4.49e-0410602PF04547
DomainAnoctamin

ANO2 ANO7

4.49e-0410602IPR007632
DomainP_typ_ATPase_c

ATP11B ATP10A

9.01e-0414602IPR032630
DomainP-type_ATPase_N

ATP11B ATP10A

9.01e-0414602IPR032631
DomainP-type_ATPase_IV

ATP11B ATP10A

9.01e-0414602IPR006539
DomainPhoLip_ATPase_C

ATP11B ATP10A

9.01e-0414602PF16212
DomainPhoLip_ATPase_N

ATP11B ATP10A

9.01e-0414602PF16209
Domain-

ATP11B ATP13A5 ATP10A

1.14e-03646033.40.50.1000
Domain-

ATP1A4 ATP2B1

1.18e-03166021.20.1110.10
DomainATPase_P-typ_TM_dom

ATP1A4 ATP2B1

1.18e-0316602IPR023298
DomainATPase_P-typ_cation-transptr_C

ATP1A4 ATP2B1

1.34e-0317602IPR006068
DomainCation_ATPase_C

ATP1A4 ATP2B1

1.34e-0317602PF00689
DomainhEGF

EYS NOTCH2

3.64e-0328602PF12661
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8I2 ANO2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

9.21e-164175619M4072
PathwayREACTOME_SENSORY_PERCEPTION

OR8I2 ANO2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR52E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 ATP2B1 OR10J1 OR10G7 OR10G4

1.55e-136365620M41834
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR8I2 OR5M9 OR4K17 OR4A5 OR6C74 OR13C2 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

2.38e-103895614M14091
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO2 ATP11B ANO7 ATP13A5 ATP1A4 ATP10A ATP2B1 RYR2

4.29e-07176568MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ANO2 ATP11B ANO7 ATP13A5 ATP1A4 ATP10A ATP2B1 RYR2

5.77e-07183568M997
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

2.46e-0655565M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP11B ATP13A5 ATP1A4 ATP10A ATP2B1

2.95e-0657565MM15643
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR10G9 OR10G8 OR10S1 OR10G7 OR10G4

8.20e-0670565MM14984
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO2 ATP11B BSG SLC44A2 ANO7 ATP13A5 LRRC8B ATP1A4 ATP10A ATP2B1 SLC36A2 RYR2

1.15e-056815612MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ANO2 ATP11B BSG SLC44A2 ANO7 ATP13A5 LRRC8B ATP1A4 ATP10A ATP2B1 SLC36A2 RYR2

2.51e-057365612M27287
PathwayREACTOME_CARDIAC_CONDUCTION

KCNK2 ATP1A4 ATP2B1 RYR2

7.38e-04103564MM15196
PathwayREACTOME_SENSORY_PERCEPTION

OR10G9 OR10G8 OR10S1 OR10G7 OR10G4

9.24e-04190565MM15687
PathwayREACTOME_INDUCTION_OF_CELL_CELL_FUSION

ANO2 ANO7

1.18e-0313562M46426
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A4 ATP2B1 RYR2

1.28e-0354563M27460
PathwayREACTOME_ION_HOMEOSTASIS

ATP1A4 ATP2B1 RYR2

1.28e-0354563MM15202
PathwayREACTOME_CARDIAC_CONDUCTION

KCNK2 ATP1A4 ATP2B1 RYR2

1.75e-03130564M27454
Pubmed

The human olfactory receptor gene family.

OR8I2 OR5M9 OR4K17 OR4A5 OR2AP1 OR6C74 OR13C2 OR4E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR4K3 OR10J1 OR10G7 OR10G4

1.34e-16541651714983052
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR8I2 OR5M9 OR4A5 OR2AP1 OR6C74 OR4E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

2.17e-15340651411875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8I2 OR5M9 OR4A5 OR2AP1 OR6C74 OR4E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

2.17e-15340651411802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR8I2 OR5M9 OR4A5 OR2AP1 OR6C74 OR4E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

2.45e-15343651432295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR8I2 OR5M9 OR4A5 OR2AP1 OR6C74 OR4E1 OR2D3 OR5T2 OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

2.76e-15346651414611657
Pubmed

DEFOG: a practical scheme for deciphering families of genes.

OR8I2 OR5M9 OR4E1 OR2D3 OR10S1 OR4K3 OR10J1

1.82e-0721965712213199
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP11B ATP1A4 ATP10A ATP2B1

2.55e-072965415071553
Pubmed

Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin.

NPTN ATP2B1

3.44e-06265230190470
Pubmed

Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance.

NPTN BSG

3.44e-06265229056295
Pubmed

Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts.

NPTN ATP2B1

1.03e-05365234948386
Pubmed

A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.

NPTN ATP2B1

1.03e-05365228827723
Pubmed

Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.

NPTN BSG

1.03e-05365227503893
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SMG1 BSG ARHGAP12 SLC44A2 OR10G9 OR10G8 ATP1A4 ATP2B1 PLXNA2 RYR2 OR10G7 OR10G4

1.29e-051442651235575683
Pubmed

Identification of an S100A8 Receptor Neuroplastin-β and its Heterodimer Formation with EMMPRIN.

NPTN BSG

2.06e-05465227388991
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

CD47 PLXNA2 CDH12 EPHA3

2.63e-059165428558017
Pubmed

Distinct expression/function of potassium and chloride channels contributes to the diverse volume regulation in cortical astrocytes of GFAP/EGFP mice.

KCNJ10 KCNK2

3.43e-05565222253765
Pubmed

ATPase reaction cycle of P4-ATPases affects their transport from the endoplasmic reticulum.

ATP11B ATP10A

3.43e-05565231571211
Pubmed

Quantitative genetic analysis of brain copper and zinc in BXD recombinant inbred mice.

KCNJ10 EPHA3

5.13e-05665216910173
Pubmed

ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.

ATP2B1 RYR2

5.13e-05665216352659
Pubmed

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.

NPTN VAMP7 SLC44A2 CD81 ATP1A4

5.26e-0521565536808153
Pubmed

Generation of monoclonal antibodies to integrin-associated proteins. Evidence that alpha3beta1 complexes with EMMPRIN/basigin/OX47/M6.

BSG CD81

7.18e-0576529360995
Pubmed

ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins.

ANO2 ANO7

7.18e-05765222075693
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

DHX36 NPTN SCAP BSG CD47 IL1RAP HECTD1 ATP2B1 NOTCH2 SIL1

7.40e-051201651035696571
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

NPTN BSG IL1RAP ATP2B1 NOTCH2 EPHA3

7.51e-0537765638117590
Pubmed

Identification of APBB1 as a substrate for anaplastic lymphoma kinase.

VAMP7 CD47 ATP2B1

7.81e-054465339115278
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

NPTN BSG VAMP7 ATP2B1 PLXNA2 NOTCH2 EPHA3

9.27e-0556965730639242
Pubmed

The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels.

ANO2 ANO7

9.56e-05865221984732
Pubmed

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.

FAIM2 CDH12

9.56e-05865219557197
Pubmed

Expression and function of epithelial anoctamins.

ANO2 ANO7

9.56e-05865220056604
Pubmed

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.

COPB1 BSG SLC44A2 CD47 CD81

1.05e-0424965530097533
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

P2RX1 KCNJ10 KCNK2 RYR2

1.37e-0413965416985003
Pubmed

The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.

ATP11B ATP10A

1.53e-041065215919184
Pubmed

Anoctamin/TMEM16 family members are Ca2+-activated Cl- channels.

ANO2 ANO7

1.53e-041065219015192
Pubmed

Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members.

ANO2 ANO7

1.53e-041065223532839
Pubmed

Structure and function of TMEM16 proteins (anoctamins).

ANO2 ANO7

1.53e-041065224692353
Pubmed

Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure.

PLXNA2 NOTCH2

2.24e-041265212421720
Pubmed

ATP9B, a P4-ATPase (a putative aminophospholipid translocase), localizes to the trans-Golgi network in a CDC50 protein-independent manner.

ATP11B ATP10A

2.24e-041265221914794
Pubmed

Differential expression of putative transbilayer amphipath transporters.

ATP11B ATP10A

2.65e-041365211015572
Pubmed

In the developing cerebral cortex: axonogenesis, synapse formation, and synaptic plasticity are regulated by SATB2 target genes.

PLXNA2 EPHA3

3.56e-041565236028553
Pubmed

Odorant and vomeronasal receptor genes in two mouse genome assemblies.

OR5M9 OR4A5 OR4E1

3.67e-047465315081110
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

NPTN COPB1 BSG VAMP7 CD47 CD81 ATP2B1 PLP2 NOTCH2

3.86e-04120365929180619
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SMG1 NPTN ATP11B VAMP7 ACVR1B ATP2B1 NOTCH2

3.86e-0471965735337019
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

PLXNA2 NOTCH2

4.06e-041665217273555
Pubmed

Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus.

ANO2 TRHR

4.59e-041765233084572
Pubmed

Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification.

KCNJ10 ATP1A4

4.59e-041765211709546
Pubmed

An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.

COPB1 KCNJ10 ATP2B1

5.33e-048465315123239
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

ATP11B ATP13A5 CD81 PLXNA2 NOTCH2

6.98e-0437665524154525
Pubmed

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.

KCNJ10 ATP1A4

7.76e-042265211431695
Pubmed

Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23.

KCNJ10 ATP1A4

7.76e-042265211401431
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

NPTN BSG CD47 FAIM2 ATP2B1

9.73e-0440565538187761
Pubmed

Semaphorin heterodimerization in cis regulates membrane targeting and neocortical wiring.

PLXNA2 CDH12

1.09e-032665239152101
Pubmed

Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis.

P2RX1 EPHA3

1.09e-032665223892084
Pubmed

Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons.

ANO2 FAIM2

1.17e-032765223090999
Pubmed

Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study.

TMEM26 RYR2

1.26e-032865223006423
Pubmed

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.

CD47 CD81

1.35e-032965222424930
Pubmed

The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development.

DHX36 ATP2B1

1.45e-033065239366945
Pubmed

The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.

COPB1 HECTD1

1.75e-033365226296893
Pubmed

Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.

BSG VAMP7 ATP2B1 NOTCH2 EPHA3

1.82e-0346765530194290
Pubmed

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate.

PLXNA2 RYR2

1.86e-033465231024170
CytobandEnsembl 112 genes in cytogenetic band chr11q24

OR10G9 OR10G8 OR10S1 OR10G7 OR10G4

7.98e-06191655chr11q24
Cytoband1q23.2

KCNJ10 ATP1A4 OR10J1

1.72e-05356531q23.2
Cytoband11q24.1

OR10G9 OR10S1 OR10G4

2.03e-053765311q24.1
Cytoband11q12.1

OR8I2 OR5M9 OR5T2

1.58e-0316165311q12.1
Cytoband14q11.2

OR4K17 OR4E1 OR4K3

2.17e-0318065314q11.2
Cytoband12q13.2

OR2AP1 OR6C74

2.79e-035565212q13.2
CytobandEnsembl 112 genes in cytogenetic band chr12q13

OR2AP1 OR6C74 ACVR1B FAIM2

3.09e-03423654chr12q13
Cytoband11q24.2

OR10G8 OR10G7

3.65e-036365211q24.2
CytobandEnsembl 112 genes in cytogenetic band chr1q23

KCNJ10 ATP1A4 OR10J1

4.11e-03226653chr1q23
Cytoband12q13

ACVR1B FAIM2

4.61e-037165212q13
GeneFamilyOlfactory receptors, family 10

OR10G9 OR10G8 OR10S1 OR10J1 OR10G7 OR10G4

4.22e-0866546157
GeneFamilyAnoctamins

ANO2 ANO7

3.88e-0410542865
GeneFamilyOlfactory receptors, family 4

OR4K17 OR4A5 OR4E1 OR4K3

5.94e-04129544151
GeneFamilyATPase phospholipid transporting

ATP11B ATP10A

8.97e-04155421210
GeneFamilyImmunoglobulin like domain containing

NPTN BSG CD47 IL1RAP

2.62e-03193544594
CoexpressionGSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP

CD47 CD81 LRRC8B IL1RAP ATP2B1 PLP2

7.17e-06200616M8290
DiseaseR-6-hydroxywarfarin to R-warfarin ratio measurement

EYS DNAH17 CDH12

1.27e-03106593EFO_0803333
Diseasecardiac hypertrophy

ATP10A PLXNA2

2.24e-0335592EFO_0002503
Diseaseprogression free survival, response to carboplatin, methylcobalamin deficiency type cblE, ovarian serous carcinoma

EYS EPHA3

3.21e-0342592EFO_0004920, EFO_1001516, GO_0097328, MONDO_0009354
DiseaseSquamous cell carcinoma of the head and neck

VAMP7 IL1RAP

4.89e-0352592C1168401
Diseasegeneralised epilepsy

ACVR1B RYR2

4.89e-0352592EFO_0005917

Protein segments in the cluster

PeptideGeneStartEntry
HEITVLIIYNLLTIV

BUB1B

856

O60566
LLEDLYVIVNIVDSI

ADAM29

221

Q9UKF5
YSVAIIILTVISIVL

ATP13A5

226

Q4VNC0
IILTVISIVLSVYDL

ATP13A5

231

Q4VNC0
IIIIVFLVINYHQRV

ACVR1B

141

P36896
VIINLVVILILDEIY

ANO2

586

Q9NQ90
KLYLIGIAAIVVAVI

CD81

201

P60033
SAITVIILVLYFVID

ATP2B1

381

P20020
IIVLQVLIPISLYVS

ATP10A

366

O60312
VVNLVFILILSKIYV

ANO7

551

Q6IWH7
LIITVTYIIIISAIL

OR8I2

211

Q8N0Y5
VFDIIAIVISYVQIL

OR52E1

206

Q8NGJ3
TQLLYLLAVAVVIIL

NOTCH2

1676

Q04721
VVYVLTVLGNLLILL

OR10G7

31

Q8NGN6
ILIVISYIFIVAAVL

OR10S1

226

Q8NGN2
VVYVLTVLGNLLILL

OR10G4

31

Q8NGN3
VYTILLIQLLVTLAV

FAIM2

106

Q9BWQ8
IYCEQALILIVILEK

EYS

2686

Q5T1H1
LLIAQLVLTTILEIF

KCNJ10

146

P78508
SVLEVLLIIFCLIVV

MGAM2

6

Q2M2H8
ATVLLVVILIVVYHV

IL1RAP

366

Q9NPH3
TVSTIFLVVVLYLII

KCNK2

61

O95069
GSLLLIIVIIVLIAY

PLXNA2

1246

O75051
VIFVDLISIIYVVIT

MRLN

31

P0DMT0
FILLVISYTIILVTV

OR4K3

211

Q96R72
VIYVVTVLGNLLIIV

OR4K17

36

Q8NGC6
DILQLVIVELIYKVC

COPB1

221

P53618
VVYVLTVLGNLLILL

OR10G8

31

Q8NGN5
YLLTVLGNQLIIILI

OR2D3

51

Q8NGH3
VVTLVLVILSYAFII

OR2AP1

206

Q8NGE2
LLLIIVSYTLIIVSI

OR13C2

211

Q8NGS9
QIIVKVILFVLIITY

LRRC8B

261

Q6P9F7
AAILYLITSIVVLVE

PLP2

91

Q04941
TVYQNQIVELILLEL

ARHGAP12

826

Q8IWW6
LVTLVLVILSYTNII

OR6C74

206

A6NCV1
GVEDVLQLLRILYIV

HECTD1

1996

Q9ULT8
VIQTILYLLECLLTE

DNAH17

2321

Q9UFH2
DLNLIVALIRYIVLE

DHX36

471

Q9H2U1
IVAEVLVLVTIIFIY

BSG

331

P35613
VAIILLTVVIYVLIG

EPHA3

551

P29320
ILAIVQIIRVILEYL

SLC44A2

511

Q8IWA5
LLCIVILLAIVVLYV

CDH12

621

P55289
LQVTNLLEYLIDVEI

CST8

76

O60676
SFVIAILVIQVIAYI

CD47

236

Q08722
ILVIQVIAYILAVVG

CD47

241

Q08722
YLVVVIGLENVLVLT

SCAP

351

Q12770
QLVLTVGLLAVVVYL

RYR2

4766

Q92736
VVYVLTVLGNLLILL

OR10G9

31

Q8NGN4
YILTLAGNIIIVTII

OR10J1

46

P30954
LTYLVTVVGNLLIVV

OR4A5

31

Q8NH83
VIFRLIQLVVLVYVI

P2RX1

31

P51575
VVVLQLYRLVVLALA

TMEM26

296

Q6ZUK4
ALEYQVVTILLVLII

TRHR

21

P34981
YVTVTLLIVSVLILT

TMEM255A

31

Q5JRV8
YIISVLNLLTLIVEQ

SMG1

496

Q96Q15
LVSLVIIIQYITQEI

SLC36A2

236

Q495M3
EVLAVRVVTLLYDLV

SIL1

326

Q9H173
VVLISYTLIVVAVLR

OR5M9

211

Q8NGP3
ELVTILIVLISYGLI

OR5T2

246

Q8NGG2
RITILTELYVQAVIF

CFAP299

211

Q6V702
DNLYLSIVLSVVVIV

ATP1A4

136

Q13733
IIYLVILISEAVIST

ATP11B

291

Q9Y2G3
HYLIIIVVLVIILAV

TNFRSF10D

211

Q9UBN6
LIFYVLTLIGNVLIV

OR4E1

36

P0C645
LTLIGNVLIVITIIY

OR4E1

41

P0C645
VVLVVSYAVILVSLR

OR4E1

216

P0C645
ILIFLCVLVIAQIVL

RNF175

56

Q8N4F7
ILAEIIILVVIIVVY

NPTN

346

Q9Y639
IIIIIVSIVFIYIIV

VAMP7

191

P51809