Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC17A2 ATP6V1E1 SLC5A7 AQP7B SLCO1B3 SLC24A3 GRIN1 MAGT1 SLC35E2B AQP7P3 AQP2 SLCO1B1 AQP7 CLDN2 SLC22A12 SLC6A8 SFXN5 SLCO1C1 SLCO4C1 SLC22A2 SLC14A2 SLC33A1 ATP2B4 SLC2A11 MFSD10 MFSD3 SLC4A11 VDAC1 GABRA3 SLC22A31

1.88e-11118012330GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC17A2 ATP6V1E1 SLC5A7 AQP7B SLCO1B3 SLC24A3 GRIN1 MAGT1 SLC35E2B AQP7P3 AQP2 SLCO1B1 AQP7 CLDN2 SLC22A12 SLC6A8 SFXN5 SLCO1C1 SLCO4C1 SLC22A2 SLC14A2 SLC33A1 ATP2B4 SLC2A11 MFSD10 MFSD3 SLC4A11 VDAC1 GABRA3 SLC22A31

1.64e-10128912330GO:0005215
GeneOntologyMolecularFunctionamide transmembrane transporter activity

AQP7B SLCO1B3 AQP7P3 SLCO1B1 AQP7 SLC14A2 SLC33A1

6.39e-09421237GO:0042887
GeneOntologyMolecularFunctionorganic hydroxy compound transmembrane transporter activity

AQP7B SLCO1B3 AQP7P3 AQP2 SLCO1B1 AQP7 SLCO1C1 MFSD10

1.13e-08701238GO:1901618
GeneOntologyMolecularFunctionG protein-coupled receptor activity

TBXA2R OR5T1 TPRA1 UTS2R OR52L1 GRM1 GRM3 GRM5 GPR146 TAS2R1 GPR174 GPR142 OR52L2P GPR62 FZD5 MRGPRG SMO ADGRE5 OR52W1 ADGRF3 OR52M1 GPR119

2.07e-0888412322GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TBXA2R OR5T1 TPRA1 UTS2R OR52L1 GRIN1 GRM1 GRM3 GRM5 GPR146 TAS2R1 GPR174 GPR142 PLXNC1 OR52L2P GPR62 FZD5 MRGPRG SMO ADGRE5 OR52W1 FGFR3 ADGRF3 TNFRSF1A OR52M1 GPR119 GABRA3

4.22e-08135312327GO:0004888
GeneOntologyMolecularFunctionwater transmembrane transporter activity

AQP7B AQP7P3 AQP2 AQP7 SLC4A11

1.18e-07201235GO:0005372
GeneOntologyMolecularFunctionurea transmembrane transporter activity

AQP7B AQP7P3 AQP7 SLC14A2

1.69e-0791234GO:0015204
GeneOntologyMolecularFunctionglycerol transmembrane transporter activity

AQP7B AQP7P3 AQP2 AQP7

1.69e-0791234GO:0015168
GeneOntologyMolecularFunctionpolyol transmembrane transporter activity

AQP7B AQP7P3 AQP2 AQP7

9.39e-07131234GO:0015166
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLCO1B3 GRIN1 SLCO1B1 SLC6A8 SFXN5 SLCO1C1 SLCO4C1 SLC22A2 SLC33A1 MFSD10 SLC4A11

2.02e-0629312311GO:0008514
GeneOntologyMolecularFunctionwater channel activity

AQP7B AQP7P3 AQP2 AQP7

3.07e-06171234GO:0015250
GeneOntologyMolecularFunctionsodium-independent organic anion transmembrane transporter activity

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

3.92e-06181234GO:0015347
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

AQP7B AQP7P3 AQP2 AQP7 SLC2A11

5.79e-06421235GO:0015144
GeneOntologyMolecularFunctionglycerol channel activity

AQP7B AQP7P3 AQP7

7.84e-0671233GO:0015254
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC17A2 ATP6V1E1 SLC5A7 SLCO1B3 SLC24A3 SLC35E2B SLCO1B1 SLC6A8 SLCO1C1 SLCO4C1 SLC22A2 ATP2B4 SLC4A11

7.90e-0647712313GO:0022804
GeneOntologyMolecularFunctioncholine transmembrane transporter activity

SLC5A7 SLC6A8 SLC22A2

1.25e-0581233GO:0015220
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC17A2 SLC5A7 SLCO1B3 SLC24A3 SLC35E2B SLCO1B1 SLC6A8 SLCO1C1 SLCO4C1 SLC4A11

1.51e-0529612310GO:0015291
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM1 GRM3 GRM5

1.86e-0591233GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM1 GRM3 GRM5

1.86e-0591233GO:0001640
GeneOntologyMolecularFunctionglutamate receptor activity

GRIN1 GRM1 GRM3 GRM5

2.16e-05271234GO:0008066
GeneOntologyMolecularFunctionPLC activating G protein-coupled glutamate receptor activity

GRM1 GRM5

3.76e-0521232GO:0001639
GeneOntologyMolecularFunctionprostaglandin transmembrane transporter activity

SLCO1B3 SLCO1B1 SLC22A2

7.90e-05141233GO:0015132
GeneOntologyMolecularFunctionicosanoid transmembrane transporter activity

SLCO1B3 SLCO1B1 SLC22A2

9.83e-05151233GO:0071714
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

GRM1 GRM5

2.24e-0441232GO:0099583
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC17A2 ATP6V1E1 SLC5A7 AQP7B SLC24A3 GRIN1 MAGT1 AQP7P3 AQP2 AQP7 SLC6A8 ATP2B4 SLC4A11 GABRA3

2.40e-0475812314GO:0015318
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLCO1B3 GRIN1 SLCO1B1 SLC6A8 SFXN5 SLCO1C1 SLC22A2

2.99e-042071237GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLCO1B3 GRIN1 SLCO1B1 SLC6A8 SFXN5 SLCO1C1 SLC22A2

3.08e-042081237GO:0005342
GeneOntologyMolecularFunctionurea channel activity

AQP7P3 AQP7

3.72e-0451232GO:0015265
GeneOntologyMolecularFunctionG protein-coupled receptor activity involved in regulation of postsynaptic membrane potential

GRM1 GRM5

3.72e-0451232GO:0099530
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLCO1B3 SLCO1B1 SLCO1C1 SLC22A2

1.07e-03731234GO:0170055
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

SLCO1B3 SLCO1B1 SLCO1C1

1.19e-03341233GO:0015125
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIN1 GRM1 GRM5 GABRA3

1.19e-03751234GO:0098960
GeneOntologyMolecularFunctionthyroid hormone transmembrane transporter activity

SLCO1B1 SLCO1C1

1.32e-0391232GO:0015349
GeneOntologyMolecularFunctionurate transmembrane transporter activity

SLC17A2 SLC22A12

1.32e-0391232GO:0015143
GeneOntologyMolecularFunctionsalt transmembrane transporter activity

SLC17A2 SLC22A12

1.32e-0391232GO:1901702
GeneOntologyMolecularFunctionchannel activity

AQP7B SLC24A3 GRIN1 AQP7P3 AQP2 AQP7 CLDN2 SLC4A11 VDAC1 GABRA3

1.53e-0352512310GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

AQP7B SLC24A3 GRIN1 AQP7P3 AQP2 AQP7 CLDN2 SLC4A11 VDAC1 GABRA3

1.55e-0352612310GO:0022803
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLCO1B3 SLCO1B1 SLC6A8 SLCO1C1

2.33e-03901234GO:0008028
GeneOntologyMolecularFunctionsymporter activity

SLC17A2 SLC5A7 SLC24A3 SLC6A8 SLC4A11

2.38e-031501235GO:0015293
GeneOntologyMolecularFunctionsodium channel regulator activity

PRSS8 ATP2B4 PCSK9

2.51e-03441233GO:0017080
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRIN1 GRM1 GRM5 GABRA3

3.41e-031001234GO:0030594
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC17A2 ATP6V1E1 SLC5A7 SLC24A3 GRIN1 MAGT1 SLC6A8 SFXN5 ATP2B4 SLC4A11 VDAC1 GABRA3

3.62e-0379312312GO:0015075
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC17A2 SLC5A7 SLC24A3 SLC6A8 SLC4A11

4.17e-031711235GO:0015081
GeneOntologyMolecularFunctionoxysterol binding

SMO VDAC1

4.27e-03161232GO:0008142
GeneOntologyMolecularFunctionoligopeptide transmembrane transporter activity

SLCO1B3 SLCO1B1

4.27e-03161232GO:0035673
GeneOntologyBiologicalProcesssodium-independent organic anion transport

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1 MFSD10

1.99e-08151235GO:0043252
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC17A2 TCAF2 ATP6V1E1 TCAF1 PRSS8 SLC5A7 CDH23 SLCO1B3 SLC24A3 GRIN1 MAGT1 AQP2 SLCO1B1 SLC22A12 SLC6A8 SFXN5 SLCO1C1 SLCO4C1 SLC22A2 KEL ATP2B4 SLC4A11 VDAC1 PCSK9 GABRA3 SLC22A31

1.20e-07137412326GO:0006811
GeneOntologyBiologicalProcessglycerol transmembrane transport

AQP7B AQP7P3 AQP2 AQP7

1.48e-0791234GO:0015793
GeneOntologyBiologicalProcesspolyol transmembrane transport

AQP7B AQP7P3 AQP2 AQP7

5.74e-07121234GO:0015791
GeneOntologyBiologicalProcessurea transmembrane transport

AQP7B AQP7P3 AQP7 SLC14A2

5.74e-07121234GO:0071918
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

TBXA2R OR5T1 TPRA1 UTS2R OR52L1 GRM1 GRM3 GRM5 ADCY8 GPR146 TAS2R1 GPR174 GPR142 OR52L2P GPR62 FZD5 VPS35 MRGPRG SMO ADGRE5 OR52W1 ADGRF3 OR52M1 ATP2B4 GPR119

6.08e-07139512325GO:0007186
GeneOntologyBiologicalProcessurea transport

AQP7B AQP7P3 AQP7 SLC14A2

1.15e-06141234GO:0015840
GeneOntologyBiologicalProcesswater transport

AQP7B AQP7P3 AQP2 AQP7 SLC4A11

1.23e-06321235GO:0006833
GeneOntologyBiologicalProcessorganic anion transport

SLC17A2 CYB5RL SLCO1B3 GRM1 SLCO1B1 SLC22A12 SLC6A8 SFXN5 SLCO1C1 SLCO4C1 SLC22A2 SLC33A1 MFSD10 SLC4A11

2.46e-0651512314GO:0015711
GeneOntologyBiologicalProcessfluid transport

AQP7B AQP7P3 AQP2 AQP7 SLC4A11

4.95e-06421235GO:0042044
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

TBXA2R GRM1 GRM3 GRM5 ADCY8 GPR62 ADGRE5 ADGRF3 ATP2B4 GPR119

8.49e-0628612310GO:0007188
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway

GRM1 GRM3 GRM5

1.69e-0591233GO:0007196
GeneOntologyBiologicalProcessregulation of type 2 mitophagy

VPS13C VDAC1

3.53e-0521232GO:1905089
GeneOntologyBiologicalProcessone-carbon compound transport

AQP7B AQP7P3 AQP7 SLC14A2

4.31e-05331234GO:0019755
GeneOntologyBiologicalProcessrenal water transport

AQP7P3 AQP2 AQP7

5.67e-05131233GO:0003097
GeneOntologyBiologicalProcessorganic hydroxy compound transport

AQP7B SLCO1B3 AQP7P3 AQP2 SLCO1B1 AQP7 SLCO1C1 SLC22A2 MFSD10 PCSK9

5.78e-0535812310GO:0015850
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled glutamate receptor signaling pathway

GRM1 GRM5

1.05e-0431232GO:0007206
GeneOntologyBiologicalProcessG protein-coupled glutamate receptor signaling pathway

GRM1 GRM3 GRM5

1.09e-04161233GO:0007216
GeneOntologyBiologicalProcessregulation of cytosolic calcium ion concentration

CDH23 GRM1 GRM5 ADCY8 ATP2B4

1.47e-04841235GO:0051480
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

TBXA2R ADCY8 GPR62 ADGRE5 ADGRF3 ATP2B4 GPR119

1.50e-041911237GO:0007189
GeneOntologyBiologicalProcesspositive regulation of establishment of protein localization

TCAF2 TCAF1 ADCY8 B3GAT3 HDAC3 ERGIC3 FZD5 VPS35 SMO TNFRSF1A

1.53e-0440312310GO:1904951
GeneOntologyBiologicalProcessSpemann organizer formation

WNT3 FZD5

2.10e-0441232GO:0060061
GeneOntologyBiologicalProcessvascular process in circulatory system

TBXA2R UTS2R BBS2 SLC24A3 ITGA9 SLCO1C1 SLC22A2 KEL ATP2B4

2.23e-043441239GO:0003018
GeneOntologyBiologicalProcesssodium ion transport

SLC17A2 PRSS8 SLC5A7 SLC24A3 SLC6A8 ATP2B4 SLC4A11 PCSK9

2.48e-042751238GO:0006814
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC17A2 PRSS8 SLC24A3 SLC6A8 ATP2B4 SLC4A11 PCSK9

2.54e-042081237GO:0035725
GeneOntologyBiologicalProcessaxon extension involved in axon guidance

WNT3 SLIT1 SMO

2.93e-04221233GO:0048846
GeneOntologyBiologicalProcessneuron projection extension involved in neuron projection guidance

WNT3 SLIT1 SMO

2.93e-04221233GO:1902284
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIN1 GRM1 GRM3 GRM5

4.25e-04591234GO:0007215
GeneOntologyBiologicalProcessrenal water homeostasis

AQP7P3 AQP2 AQP7

4.87e-04261233GO:0003091
GeneOntologyBiologicalProcessregulation of anion channel activity

TCAF2 TCAF1

5.21e-0461232GO:0010359
GeneOntologyBiologicalProcesscalcium ion homeostasis

CDH23 SLC24A3 GRIN1 GRM1 GRM5 ADCY8 KEL FGFR3 ATP2B4

5.47e-043891239GO:0055074
GeneOntologyCellularComponentbasal plasma membrane

MYO1A AQP7B SLCO1B3 AQP7P3 ITGA9 AQP2 SLCO1B1 AQP7 ADCY8 SLCO1C1 SLCO4C1 PROM2 SLC22A2 SLC14A2 ATP2B4 SLC4A11

3.38e-1035412416GO:0009925
GeneOntologyCellularComponentbasolateral plasma membrane

MYO1A AQP7B SLCO1B3 AQP7P3 AQP2 SLCO1B1 AQP7 ADCY8 SLCO1C1 SLCO4C1 PROM2 SLC22A2 SLC14A2 ATP2B4 SLC4A11

7.61e-1032012415GO:0016323
GeneOntologyCellularComponentbasal part of cell

MYO1A AQP7B SLCO1B3 AQP7P3 ITGA9 AQP2 SLCO1B1 AQP7 ADCY8 SLCO1C1 SLCO4C1 PROM2 SLC22A2 SLC14A2 ATP2B4 SLC4A11

8.78e-1037812416GO:0045178
GeneOntologyCellularComponentvesicle membrane

ATP6V1E1 SYN3 VPS13C WNT3 SLC5A7 SCAMP2 GRIN1 ITGA2B MAGT1 AQP2 AQP7 ADCY8 SEC24D SLCO4C1 GPR62 FZD5 SLC22A2 VPS35 LHFPL2 SMO ADGRE5 MFSD10 SLC4A11 PCSK9

8.11e-07132512424GO:0012506
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ATP6V1E1 SYN3 VPS13C WNT3 SLC5A7 SCAMP2 GRIN1 ITGA2B MAGT1 AQP2 AQP7 ADCY8 SEC24D SLCO4C1 GPR62 FZD5 SLC22A2 VPS35 LHFPL2 SMO ADGRE5 MFSD10 PCSK9

2.33e-06130712423GO:0030659
GeneOntologyCellularComponentapical plasma membrane

SLC17A2 ATP6V1E1 MYO1A SLC5A7 AQP2 ADCY8 SLC22A12 SLC6A8 PROM2 SLC22A2 KNCN SLC14A2 SLC4A11

6.63e-0648712413GO:0016324
GeneOntologyCellularComponentcluster of actin-based cell projections

FLII MYO1A BBS2 CDH23 AQP7P3 AQP7 SLC22A12 KNCN MFSD10

7.47e-062231249GO:0098862
GeneOntologyCellularComponentapical part of cell

SLC17A2 ATP6V1E1 MYO1A SLC5A7 CDH23 AQP2 ADCY8 SLC22A12 SLC6A8 PROM2 SLC22A2 KNCN SLC14A2 SLC4A11

1.14e-0559212414GO:0045177
GeneOntologyCellularComponentpresynaptic membrane

SLC5A7 GRIN1 GRM1 GRM3 ADCY8 SLC22A2 ATP2B4 VDAC1 GABRA3

4.16e-052771249GO:0042734
GeneOntologyCellularComponentpresynaptic active zone

GRIN1 GRM3 ADCY8 ATP2B4 VDAC1 GABRA3

1.97e-041411246GO:0048786
GeneOntologyCellularComponentbrush border

FLII MYO1A AQP7P3 AQP7 SLC22A12 MFSD10

2.95e-041521246GO:0005903
GeneOntologyCellularComponentcoated vesicle

ATP6V1E1 SLC5A7 ECPAS AQP2 ADCY8 SEC24D ERGIC3 FZD5 PCSK9

3.01e-043601249GO:0030135
GeneOntologyCellularComponentmembrane raft

PRSS8 MYO1A SLC5A7 ADCY8 PROM2 SMO TNFRSF1A ATP2B4 VDAC1

3.13e-043621249GO:0045121
GeneOntologyCellularComponentmembrane microdomain

PRSS8 MYO1A SLC5A7 ADCY8 PROM2 SMO TNFRSF1A ATP2B4 VDAC1

3.26e-043641249GO:0098857
GeneOntologyCellularComponentsynaptic membrane

SLC5A7 GRIN1 GRM1 GRM3 GRM5 ADCY8 SLC6A8 SLC22A2 ATP2B4 VDAC1 GABRA3

7.11e-0458312411GO:0097060
GeneOntologyCellularComponentcell projection membrane

BBS2 GRIN1 AQP7P3 AQP7 SLC22A12 PROM2 SMO MFSD10 GABRA3

1.09e-034311249GO:0031253
GeneOntologyCellularComponentpresynaptic active zone membrane

GRIN1 ATP2B4 VDAC1 GABRA3

1.20e-03781244GO:0048787
GeneOntologyCellularComponentbrush border membrane

AQP7P3 AQP7 SLC22A12 MFSD10

1.51e-03831244GO:0031526
GeneOntologyCellularComponenttransport vesicle membrane

ATP6V1E1 SYN3 SLC5A7 GRIN1 AQP2 SEC24D SLC22A2

1.85e-032931247GO:0030658
GeneOntologyCellularComponentplasma membrane raft

MYO1A SLC5A7 ADCY8 SMO ATP2B4

1.85e-031471245GO:0044853
GeneOntologyCellularComponentasymmetric synapse

SYN3 GRIN1 GRM1 GRM3 GRM5 ADCY8 PLXNC1 VPS35 VDAC1

2.18e-034771249GO:0032279
GeneOntologyCellularComponentreceptor complex

GRIN1 ITGA2B GRM1 ITGA9 PLXNC1 GPR62 FGFR3 TNFRSF1A GPR119 GABRA3

2.44e-0358112410GO:0043235
GeneOntologyCellularComponentexocytic vesicle

ATP6V1E1 SYN3 SLC5A7 GRIN1 AQP2 SLC22A2 VDAC1

3.02e-033201247GO:0070382
GeneOntologyCellularComponent9+2 non-motile cilium

CDH23 KNCN

3.03e-03141242GO:0097732
GeneOntologyCellularComponentkinocilium

CDH23 KNCN

3.03e-03141242GO:0060091
GeneOntologyCellularComponentpostsynaptic specialization

SYN3 GRIN1 GRM1 GRM3 GRM5 ADCY8 VPS35 VDAC1 GABRA3

3.11e-035031249GO:0099572
GeneOntologyCellularComponentglutamatergic synapse

SYN3 GRIN1 GRM1 GRM3 GRM5 ADCY8 TRIM3 SLC6A8 PLXNC1 FZD5 VPS35 ATP2B4

3.41e-0381712412GO:0098978
GeneOntologyCellularComponenttransport vesicle

ATP6V1E1 SYN3 SLC5A7 GRIN1 AQP2 SEC24D SLC22A2 FGFR3 VDAC1

3.81e-035191249GO:0030133
GeneOntologyCellularComponentneuron to neuron synapse

SYN3 GRIN1 GRM1 GRM3 GRM5 ADCY8 PLXNC1 VPS35 VDAC1

4.01e-035231249GO:0098984
GeneOntologyCellularComponentCOPII-coated ER to Golgi transport vesicle

ECPAS SEC24D ERGIC3 PCSK9

4.20e-031101244GO:0030134
GeneOntologyCellularComponentexocytic vesicle membrane

ATP6V1E1 SYN3 SLC5A7 GRIN1 SLC22A2

4.32e-031791245GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

ATP6V1E1 SYN3 SLC5A7 GRIN1 SLC22A2

4.32e-031791245GO:0030672
GeneOntologyCellularComponentplatelet alpha granule membrane

ITGA2B LHFPL2

4.48e-03171242GO:0031092
DomainMFS_dom

SLC17A2 SLCO1B3 SLCO1B1 SLC22A12 SLCO1C1 SLCO4C1 SLC22A2 SLC33A1 SLC2A11 MFSD10 MFSD3 SLC22A31

6.80e-1113412112IPR020846
DomainMFS

SLC17A2 SLCO1B3 SLCO1B1 SLC22A12 SLCO1C1 SLCO4C1 SLC22A2 SLC2A11 MFSD10 MFSD3 SLC22A31

1.08e-1010812111PS50850
DomainOA_transporter

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

7.97e-07121214IPR004156
DomainOATP

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

7.97e-07121214PF03137
DomainGPCR_3_mtglu_rcpt

GRM1 GRM3 GRM5

1.45e-0581213IPR000162
DomainGPCR_3_mtglu_rcpt_5

GRM1 GRM5

4.16e-0521212IPR000202
DomainGluR_Homer-bdg

GRM1 GRM5

4.16e-0521212PF10606
DomainPeptidase_M60_dom

TCAF2 TCAF1

4.16e-0521212IPR031161
DomainPeptidase_M60

TCAF2 TCAF1

4.16e-0521212PF13402
DomainMetabotropic_Glu_rcpt_Homer-bd

GRM1 GRM5

4.16e-0521212IPR019588
DomainM60-like

TCAF2 TCAF1

4.16e-0521212SM01276
DomainGPCR_3_mtglu_rcpt_1

GRM1 GRM5

4.16e-0521212IPR001256
DomainPEPTIDASE_M60

TCAF2 TCAF1

4.16e-0521212PS51723
DomainGluR_Homer-bdg

GRM1 GRM5

4.16e-0521212SM01229
DomainClass_I_gatase-like

TCAF2 TCAF1 PFAS

5.59e-05121213IPR029062
DomainNCD3G

GRM1 GRM3 GRM5

7.23e-05131213PF07562
DomainGPCR_3_9-Cys_dom

GRM1 GRM3 GRM5

7.23e-05131213IPR011500
DomainMFS_sugar_transport-like

SLC22A12 SLC22A2 SLC2A11 SLC22A31

8.41e-05361214IPR005828
DomainSugar_tr

SLC22A12 SLC22A2 SLC2A11 SLC22A31

8.41e-05361214PF00083
DomainKazal_2

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

8.41e-05361214PF07648
DomainGPCR_3_CS

GRM1 GRM3 GRM5

9.16e-05141213IPR017979
DomainANF_lig-bd_rcpt

GRIN1 GRM1 GRM3 GRM5

9.38e-05371214IPR001828
DomainANF_receptor

GRIN1 GRM1 GRM3 GRM5

9.38e-05371214PF01094
DomainPeripla_BP_I

GRIN1 GRM1 GRM3 GRM5

1.16e-04391214IPR028082
DomainKAZAL_2

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

3.07e-04501214PS51465
DomainGPCR_3

GRM1 GRM3 GRM5

3.24e-04211213IPR000337
DomainKazal_dom

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

3.31e-04511214IPR002350
Domain7tm_3

GRM1 GRM3 GRM5

3.73e-04221213PF00003
DomainG_PROTEIN_RECEP_F3_2

GRM1 GRM3 GRM5

3.73e-04221213PS00980
DomainG_PROTEIN_RECEP_F3_3

GRM1 GRM3 GRM5

3.73e-04221213PS00981
DomainG_PROTEIN_RECEP_F3_1

GRM1 GRM3 GRM5

3.73e-04221213PS00979
DomainG_PROTEIN_RECEP_F3_4

GRM1 GRM3 GRM5

3.73e-04221213PS50259
DomainGPCR_3_C

GRM1 GRM3 GRM5

3.73e-04221213IPR017978
DomainFG-GAP

BBS2 ITGA2B ITGA9

4.86e-04241213PF01839
DomainFG-GAP

BBS2 ITGA2B ITGA9

4.86e-04241213IPR013517
DomainGPCR_2-like

FZD5 SMO ADGRE5 ADGRF3

6.18e-04601214IPR017981
DomainG_PROTEIN_RECEP_F2_4

FZD5 SMO ADGRE5 ADGRF3

6.58e-04611214PS50261
DomainGPCR_Rhodpsn_7TM

TBXA2R OR5T1 UTS2R OR52L1 GPR146 GPR174 GPR142 GPR62 MRGPRG OR52W1 OR52M1 GPR119

1.36e-0367012112IPR017452
Domain7tm_1

TBXA2R OR5T1 UTS2R OR52L1 GPR146 GPR174 GPR142 GPR62 MRGPRG OR52W1 OR52M1 GPR119

1.49e-0367712112PF00001
DomainMFS_1

SLC17A2 SLC22A12 MFSD10 MFSD3

1.58e-03771214PF07690
DomainMFS

SLC17A2 SLC22A12 MFSD10 MFSD3

1.58e-03771214IPR011701
DomainG_PROTEIN_RECEP_F1_1

TBXA2R OR5T1 UTS2R OR52L1 GPR146 GPR174 GPR142 GPR62 MRGPRG OR52W1 OR52M1 GPR119

1.64e-0368512112PS00237
DomainG_PROTEIN_RECEP_F1_2

TBXA2R OR5T1 UTS2R OR52L1 GPR146 GPR174 GPR142 GPR62 MRGPRG OR52W1 OR52M1 GPR119

1.76e-0369112112PS50262
DomainGPCR_Rhodpsn

TBXA2R OR5T1 UTS2R OR52L1 GPR146 GPR174 GPR142 GPR62 MRGPRG OR52W1 OR52M1 GPR119

1.79e-0369212112IPR000276
DomainFrizzled

FZD5 SMO

2.20e-03111212IPR000539
DomainFrizzled

FZD5 SMO

2.20e-03111212PF01534
DomainFrizzled

FZD5 SMO

2.20e-03111212SM01330
DomainKAZAL

SLCO1B3 SLCO1B1 SLCO1C1

3.29e-03461213SM00280
DomainGelsolin

FLII SEC24D

3.60e-03141212PF00626
DomainMIP

AQP2 AQP7

3.60e-03141212PS00221
DomainMIP

AQP2 AQP7

3.60e-03141212PF00230
DomainGelsolin-like_dom

FLII SEC24D

3.60e-03141212IPR007123
DomainMIP

AQP2 AQP7

4.14e-03151212IPR000425
Domain-

AQP2 AQP7

4.14e-031512121.20.1080.10
DomainAquaporin-like

AQP2 AQP7

4.14e-03151212IPR023271
DomainIntegrin_alpha_C_CS

ITGA2B ITGA9

4.71e-03161212IPR018184
DomainFrizzled/SFRP

FZD5 SMO

4.71e-03161212IPR015526
DomainSUGAR_TRANSPORT_2

SLC22A2 SLC2A11

5.31e-03171212PS00217
DomainIntegrin_alpha-2

ITGA2B ITGA9

5.95e-03181212IPR013649
DomainIntegrin_alpha2

ITGA2B ITGA9

5.95e-03181212PF08441
DomainIntegrin_alpha

ITGA2B ITGA9

5.95e-03181212IPR000413
DomainINTEGRIN_ALPHA

ITGA2B ITGA9

5.95e-03181212PS00242
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V1E1 CYB5RL SLC5A7 SLCO1B3 SLC24A3 MAGT1 AQP2 SLCO1B1 AQP7 ADCY8 SLC22A12 SLCO1C1 SLCO4C1 SLC22A2 SLC14A2 SLC33A1 ATP2B4 SLC2A11 VDAC1 PCSK9

5.06e-087369320M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V1E1 CYB5RL SLC5A7 SLCO1B3 SLC24A3 MAGT1 AQP7P3 AQP2 SLCO1B1 AQP7 SLC22A12 SLCO1C1 SLCO4C1 SLC22A2 SLC14A2 SLC33A1 ATP2B4 PCSK9

3.97e-076819318MM14985
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

5.65e-0711934M930
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC5A7 SLCO1B3 SLC24A3 SLCO1B1 SLC22A12 SLCO1C1 SLCO4C1 SLC22A2 SLC14A2 SLC33A1 SLC2A11

7.12e-072499311M5988
PathwayREACTOME_TRANSPORT_OF_ORGANIC_ANIONS

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

8.44e-0712934MM15476
PathwayWP_GPCRS_NONODORANT

TBXA2R UTS2R GRM1 GRM3 GRM5 TAS2R1 GPR174 FZD5 SMO ADGRE5 GPR119

1.36e-062669311MM15843
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC5A7 SLCO1B3 SLC24A3 SLCO1B1 SLC22A12 SLCO1C1 SLCO4C1 SLC22A2 SLC14A2 SLC33A1

3.69e-062389310MM15076
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1 SLC33A1

6.96e-0641935MM15075
PathwayREACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1 SLC33A1

8.85e-0643935M881
PathwayREACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS

AQP7P3 AQP2 AQP7

7.58e-0513933MM15095
PathwayWP_SULFATASE_AND_AROMATASE_PATHWAY

SLCO1B3 SLCO1B1 SLCO4C1

9.60e-0514933M48085
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM1 GRM3 GRM5 TAS2R1

9.92e-0537934MM15067
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM1 GRM3 GRM5

1.19e-0415933M39442
PathwayWP_GPCRS_CLASS_C_METABOTROPIC_GLUTAMATE_PHEROMONE

GRM1 GRM3 GRM5

1.19e-0415933MM15845
PathwayREACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS

GRM1 GRM3 GRM5 TAS2R1

1.22e-0439934M793
PathwayWP_COMMON_PATHWAYS_UNDERLYING_DRUG_ADDICTION

GRIN1 GRM1 GRM5 ADCY8

1.49e-0441934M39655
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

TBXA2R GRIN1 GRM1 GRM5 ADCY8 ATP2B4 VDAC1

1.73e-04178937M2890
PathwayREACTOME_GPCR_LIGAND_BINDING

TBXA2R UTS2R WNT3 GRM1 GRM3 GRM5 TAS2R1 FZD5 KEL SMO ADGRE5

2.29e-044639311M507
PathwayWP_GPCRS_OTHER

GRM1 GPR146 FZD5 SMO ADGRE5

4.27e-0496935MM15939
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC5A7 SLCO1B3 SLCO1B1 SLC22A12 SLC33A1

4.92e-0499935M27474
PathwayWP_GPCRS_ODORANT

OR5T1 TPRA1 GPR146 GPR142 MRGPRG ADGRF3

5.95e-04157936MM15872
Pubmed

Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

1.10e-088125419129463
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

TPRA1 GRM5 GPR146 GPR142 GPR62 MRGPRG ADGRF3

1.53e-0879125712679517
Pubmed

Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.

SLCO1B3 SLCO1B1 SLCO1C1 SLCO4C1

5.15e-0811125414579113
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

SLCO1B3 SLCO1B1 CLDN2 SLCO1C1 SLCO4C1 SLC22A2 SMO SLC14A2 SLC4A11

8.13e-08212125919521566
Pubmed

Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain.

SLCO1B3 SLCO1B1 SLCO1C1

1.81e-074125322294745
Pubmed

Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system.

GRM1 GRM3 GRM5

1.81e-074125329079293
Pubmed

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.

GRIN1 GRM1 GRM3 GRM5 GABRA3

6.02e-0745125525979088
Pubmed

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.

PFAS SCAMP2 MAGT1 ECPAS B3GAT3 CHPF2 SLC33A1 ATP2B4 MFSD10

8.97e-07282125935007762
Pubmed

Restricted expression of mouse GCMa/Gcm1 in kidney and thymus.

AQP7P3 AQP2 AQP7

8.99e-076125312351183
Pubmed

Regulatory pathway analysis by high-throughput in situ hybridization.

WNT3 GRIN1 GRM1 GRM3 ADCY8 PLXNC1

9.92e-0791125617953485
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

GRIN1 GRM1 BCL11B GABRA3

1.11e-0622125435245678
Pubmed

Metabotropic glutamate receptor subtype 7 ablation causes deficit in fear response and conditioned taste aversion.

GRM1 GRM3 GRM5

1.57e-06712539920659
Pubmed

Role of aquaporin water channels in kidney and lung.

AQP7P3 AQP2 AQP7

1.57e-06712539822113
Pubmed

Lessons on renal physiology from transgenic mice lacking aquaporin water channels.

AQP7P3 AQP2 AQP7

1.57e-067125310232700
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIN1 GRM1 GRM3 GRM5

1.60e-0624125435746896
Pubmed

Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.

GRM1 GRM3 GRM5

2.50e-068125311850456
Pubmed

Aquaporin molecular biology and clinical abnormalities of the water transport channels.

AQP7P3 AQP2 AQP7

3.75e-06912539757370
Pubmed

Expression of mRNAs of the aquaporin family in mouse oocytes and embryos.

AQP7P3 AQP2 AQP7

5.34e-0610125310788316
Pubmed

Expression patterns of aquaporins in the inner ear: evidence for concerted actions of multiple types of aquaporins to facilitate water transport in the cochlea.

AQP7P3 AQP2 AQP7

5.34e-0610125312031518
Pubmed

mRNAs encoding aquaporins are present during murine preimplantation development.

AQP7P3 AQP2 AQP7

5.34e-0610125311066060
Pubmed

Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.

GRM1 GRM3 GRM5

5.34e-061012539069281
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GRIN1 GRM1 GRM3 GRM5 GABRA3

1.14e-0581125522723691
Pubmed

Cyclic ADP ribose-dependent Ca2+ release by group I metabotropic glutamate receptors in acutely dissociated rat hippocampal neurons.

GRM1 GRM5

1.28e-052125222028929
Pubmed

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP.

GRM1 GRM5

1.28e-05212529185557
Pubmed

Over-expression of AQP7 contributes to improve insulin resistance in adipocytes.

AQP7P3 AQP7

1.28e-052125222877989
Pubmed

Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc.

GRIN1 GRM1

1.28e-052125219597494
Pubmed

Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis.

SLCO1B3 SLCO1B1

1.28e-052125229944058
Pubmed

SLCO1B1 and SLCO1B3 genetic mutations in Taiwanese patients with Rotor syndrome.

SLCO1B3 SLCO1B1

1.28e-052125236964102
Pubmed

AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability.

SLC33A1 PCSK9

1.28e-052125220826464
Pubmed

mGluR₁,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice.

GRM1 GRM5

1.28e-052125222681774
Pubmed

Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronide.

SLCO1B3 SLCO1B1

1.28e-052125223340295
Pubmed

Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.

SLCO1B3 SLCO1B1

1.28e-052125229777022
Pubmed

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

SLCO1B3 SLCO1B1

1.28e-052125226191226
Pubmed

Aquaporin 7 is upregulated through the PI3K-Akt pathway and modulates decidualisation of endometrial stromal cells.

AQP7P3 AQP7

1.28e-052125237879294
Pubmed

Prolonged Starvation Causes Up-Regulation of AQP1 in Adipose Tissue Capillaries of AQP7 Knock-Out Mice.

AQP7P3 AQP7

1.28e-052125227455244
Pubmed

Involvement of aquaporin-7 in the cutaneous primary immune response through modulation of antigen uptake and migration in dendritic cells.

AQP7P3 AQP7

1.28e-052125221968069
Pubmed

Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

SLCO1B3 SLCO1B1

1.28e-052125224194513
Pubmed

mGluR1,5 activation protects cortical astrocytes and GABAergic neurons from ischemia-induced impairment.

GRM1 GRM5

1.28e-052125223280324
Pubmed

Effects of hyperosmolality on expression of urea transporter A2 and aquaporin 2 in mouse medullary collecting duct cells.

AQP2 SLC14A2

1.28e-052125222282246
Pubmed

Metabotropic glutamate receptors in the main olfactory bulb drive granule cell-mediated inhibition.

GRM1 GRM5

1.28e-052125217093122
Pubmed

Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.

SLCO1B3 SLCO1B1

1.28e-052125224855184
Pubmed

Aquaporin-7 Facilitates Proliferation and Adipogenic Differentiation of Mouse Bone Marrow Mesenchymal Stem Cells by Regulating Hydrogen Peroxide Transport.

AQP7P3 AQP7

1.28e-052125237432580
Pubmed

Aquaporin 7 is a beta-cell protein and regulator of intraislet glycerol content and glycerol kinase activity, beta-cell mass, and insulin production and secretion.

AQP7P3 AQP7

1.28e-052125217576812
Pubmed

Preclinical Mouse Models To Study Human OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions in Vivo.

SLCO1B3 SLCO1B1

1.28e-052125226474710
Pubmed

Effects of anthocyans on the expression of organic anion transporting polypeptides (SLCOs/OATPs) in primary human hepatocytes.

SLCO1B3 SLCO1B1

1.28e-052125225578040
Pubmed

Prediction of organic anion-transporting polypeptide 1B1- and 1B3-mediated hepatic uptake of statins based on transporter protein expression and activity data.

SLCO1B3 SLCO1B1

1.28e-052125224989890
Pubmed

Activation of NMDA receptors reduces metabotropic glutamate receptor-induced long-term depression in the nucleus accumbens via a CaMKII-dependent mechanism.

GRIN1 GRM5

1.28e-052125222947307
Pubmed

In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

GRM1 GRM5

1.28e-052125231102766
Pubmed

Expression of organic anion-transporting polypeptides 1B1 and 1B3 in ovarian cancer cells: relevance for paclitaxel transport.

SLCO1B3 SLCO1B1

1.28e-052125221719246
Pubmed

Organic anion transporting polypeptide 1B1 (OATP1B1) and OATP1B3: genetic variability and haplotype analysis in white Canadians.

SLCO1B3 SLCO1B1

1.28e-052125220877131
Pubmed

Aquaporin 7 expression in postimplantation mouse uteri: a potential role for glycerol transport in uterine decidualization.

AQP7P3 AQP7

1.28e-052125221130427
Pubmed

The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.

AQP7P3 AQP7

1.28e-052125219297367
Pubmed

Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.28e-052125216534140
Pubmed

Dynamic subcellular localization of aquaporin-7 in white adipocytes.

AQP7P3 AQP7

1.28e-052125225643985
Pubmed

Molecular characterization of human Aquaporin-7 gene and its chromosomal mapping.

AQP7P3 AQP7

1.28e-05212529714739
Pubmed

Effect of pregnane X receptor ligands on transport mediated by human OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.28e-052125218321482
Pubmed

Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney.

SLCO1B3 SLCO4C1

1.28e-052125214993604
Pubmed

Corticostriatal LTP requires combined mGluR1 and mGluR5 activation.

GRM1 GRM5

1.28e-052125212559117
Pubmed

Expression of metabotropic glutamate receptor mRNAs in the human spinal cord: implications for selective vulnerability of spinal motor neurons in amyotrophic lateral sclerosis.

GRM1 GRM3

1.28e-052125211535235
Pubmed

Involvement of group I metabotropic glutamate receptors and glutamate transporters in the slow excitatory synaptic transmission in the spinal cord dorsal horn.

GRM1 GRM5

1.28e-052125218554818
Pubmed

Interaction of oral antidiabetic drugs with hepatic uptake transporters: focus on organic anion transporting polypeptides and organic cation transporter 1.

SLCO1B3 SLCO1B1

1.28e-052125218314419
Pubmed

OATP 1B1/1B3 expression in hepatocellular carcinomas treated with orthotopic liver transplantation.

SLCO1B3 SLCO1B1

1.28e-052125221691816
Pubmed

Cryoprotectants up-regulate expression of mouse oocyte AQP7, which facilitates water diffusion during cryopreservation.

AQP7P3 AQP7

1.28e-052125223290745
Pubmed

Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex.

GRM1 GRM5

1.28e-052125227392515
Pubmed

Linking organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1 and OATP1B3) interaction profiles to hepatotoxicity - The hyperbilirubinemia use case.

SLCO1B3 SLCO1B1

1.28e-052125228063966
Pubmed

Activating mGlu3 Metabotropic Glutamate Receptors Rescues Schizophrenia-like Cognitive Deficits Through Metaplastic Adaptations Within the Hippocampus.

GRM3 GRM5

1.28e-052125233965197
Pubmed

Genetic inactivation of mGlu5 receptor improves motor coordination in the Grm1crv4 mouse model of SCAR13 ataxia.

GRM1 GRM5

1.28e-052125228982591
Pubmed

Long-lasting inhibitory effects of cyclosporin A, but not tacrolimus, on OATP1B1- and OATP1B3-mediated uptake.

SLCO1B3 SLCO1B1

1.28e-052125222240838
Pubmed

Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors.

GRIN1 GRM5

1.28e-052125218182392
Pubmed

Aquaporin-7 Regulates the Response to Cellular Stress in Breast Cancer.

AQP7P3 AQP7

1.28e-052125232631905
Pubmed

DNA and RNA sequencing identified a novel oncogene VPS35 in liver hepatocellular carcinoma.

VPS35 FGFR3

1.28e-052125232071398
Pubmed

Human organic anion transporter 1B1 and 1B3 function as bidirectional carriers and do not mediate GSH-bile acid cotransport.

SLCO1B3 SLCO1B1

1.28e-052125217412826
Pubmed

Evidence for opposing selective forces operating on human-specific duplicated TCAF genes in Neanderthals and humans.

TCAF2 TCAF1

1.28e-052125234433829
Pubmed

Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel.

AQP7P3 AQP7

1.28e-052125211457862
Pubmed

Selective induction of metabotropic glutamate receptor 1- and metabotropic glutamate receptor 5-dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus.

GRM1 GRM5

1.28e-052125218035501
Pubmed

Cardioprotective effect of St. Thomas' Hospital No. 2 solution against age-related changes in aquaporin-7-deficient mice.

AQP7P3 AQP7

1.28e-052125237691043
Pubmed

Determination of group I metabotropic glutamate receptor subtypes involved in the frequency of epileptiform activity in vitro using mGluR1 and mGluR5 mutant mice.

GRM1 GRM5

1.28e-052125212623213
Pubmed

Aquaporin7 expression during perinatal development of mouse brain.

AQP7P3 AQP7

1.28e-052125217052846
Pubmed

Visualization of hepatic uptake transporter function in healthy subjects by using gadoxetic acid-enhanced MR imaging.

SLCO1B3 SLCO1B1

1.28e-052125222771883
Pubmed

Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation.

GRM1 GRM5

1.28e-052125215184389
Pubmed

Establishment of a set of double transfectants coexpressing organic anion transporting polypeptide 1B3 and hepatic efflux transporters for the characterization of the hepatobiliary transport of telmisartan acylglucuronide.

SLCO1B3 SLCO1B1

1.28e-052125218180273
Pubmed

Morphologic and functional analysis of sperm and testes in Aquaporin 7 knockout mice.

AQP7P3 AQP7

1.28e-052125217123523
Pubmed

Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

GRM1 GRM5

1.28e-052125211591458
Pubmed

Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.

AQP7P3 AQP7

1.28e-052125211972053
Pubmed

Structure of human drug transporters OATP1B1 and OATP1B3.

SLCO1B3 SLCO1B1

1.28e-052125237723174
Pubmed

Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue.

AQP7P3 AQP7

1.28e-052125215591341
Pubmed

Vps35-deficiency impairs SLC4A11 trafficking and promotes corneal dystrophy.

VPS35 SLC4A11

1.28e-052125228934248
Pubmed

Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.

GRM1 GRM5

1.28e-052125233279506
Pubmed

Effects of Rifampin, a potent inducer of drug-metabolizing enzymes and an inhibitor of OATP1B1/3 transport, on the single dose pharmacokinetics of anacetrapib.

SLCO1B3 SLCO1B1

1.28e-052125223670789
Pubmed

Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation.

AQP7P3 AQP7

1.28e-052125215746100
Pubmed

Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil.

SLCO1B3 SLCO1B1

1.28e-052125217496208
Pubmed

Rotor Syndrome

SLCO1B3 SLCO1B1

1.28e-052125223236639
Pubmed

Aquaporin7 plays a crucial role in tolerance to hyperosmotic stress and in the survival of oocytes during cryopreservation.

AQP7P3 AQP7

1.28e-052125226634435
Pubmed

Metabotropic glutamate receptors are expressed in adult human glial progenitor cells.

GRM3 GRM5

1.28e-052125215158450
Pubmed

Expression Patterns of Organic Anion Transporting Polypeptides 1B1 and 1B3 Protein in Human Pediatric Liver.

SLCO1B3 SLCO1B1

1.28e-052125227098745
Pubmed

Introduction of aromatic ring-containing substituents in cyclic nucleotides is associated with inhibition of toxin uptake by the hepatocyte transporters OATP 1B1 and 1B3.

SLCO1B3 SLCO1B1

1.28e-052125224740327
Pubmed

Glutamate-dependent neuroglial calcium signaling differs between young and adult brain.

GRM3 GRM5

1.28e-052125223307741
Pubmed

Expression and functional role of mGluR3 and mGluR5 in human astrocytes and glioma cells: opposite regulation of glutamate transporter proteins.

GRM3 GRM5

1.28e-052125212786977
Pubmed

UGT-dependent regioselective glucuronidation of ursodeoxycholic acid and obeticholic acid and selective transport of the consequent acyl glucuronides by OATP1B1 and 1B3.

SLCO1B3 SLCO1B1

1.28e-052125231299240
Pubmed

AQP7 is localized in capillaries of adipose tissue, cardiac and striated muscle: implications in glycerol metabolism.

AQP7P3 AQP7

1.28e-052125217077387
InteractionGPR35 interactions

SCAMP2 B3GAT3 GPR146 OXA1L ERGIC3 ADGRE5 SLC33A1 MFSD3 VDAC1

6.53e-081331149int:GPR35
InteractionPLD3 interactions

SCAMP2 ITGA2B MAGT1 ECPAS B3GAT3 CHPF2 SLC33A1 ATP2B4 MFSD10

1.11e-052461149int:PLD3
InteractionSLC47A1 interactions

SLC17A2 ECPAS SLCO4C1 SLC22A2 GABRA3

1.23e-05531145int:SLC47A1
Cytoband11p15.4

DNHD1 OR52L1 OR52L2P MRGPRG OR52W1 OR52M1

1.93e-05200125611p15.4
GeneFamilySolute carriers

SLC17A2 SLC5A7 SLCO1B3 SLC24A3 SLC35E2B SLCO1B1 SLC22A12 SLC6A8 SLCO1C1 SLCO4C1 SLC22A2 SLC14A2 SLC33A1 SLC2A11 SLC4A11 SLC22A31

9.79e-113959016752
GeneFamilyG protein-coupled receptors, Class A orphans

GPR146 GPR174 GPR142 GPR62 MRGPRG GPR119

2.48e-0678906262
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM1 GRM3 GRM5

6.56e-068903281
GeneFamilyOlfactory receptors, family 52

OR52L1 OR52L2P OR52W1 OR52M1

1.03e-0449904165
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ITGA2B PTGFRN BTN3A1 PLXNC1 KEL ADGRE5 FGFR3 TNFRSF1A

7.74e-04394908471
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD5 SMO

1.31e-0311902286
GeneFamilyAquaporins

AQP2 AQP7

2.14e-0314902305
GeneFamilyCD molecules|Integrin alpha subunits

ITGA2B ITGA9

3.56e-03189021160
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

NAPSA PRSS8 DNAJC22 CLDN2 SLC22A12 FZD5 SLC22A2 FGFR3 PCSK9

1.51e-052671159gudmap_developingKidney_e14.5 whole kidney - wildtype_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_200

NAPSA PRSS8 DNAJC22 CLDN2 SLC22A12 SLC22A2 PCSK9

1.84e-051511157gudmap_developingKidney_e15.5_early proxim tubul_200
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 AQP7 ADCY8 SLCO4C1 MSLN SLC22A31

3.35e-071601247ac5d573c135d66d6adddd42dfddd9d3e01532172
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 AQP7 ADCY8 SLCO4C1 MSLN SLC22A31

3.35e-071601247b81d218c20fe37921cf3c6c7db2da3bfd367230a
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC17A2 PRSS8 SYN3 TRIM3 RNASE4 FZD5 MSLN

7.98e-071821247573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC17A2 PRSS8 SYN3 TRIM3 RNASE4 FZD5 MSLN

7.98e-0718212476cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellfacs-Thymus-nan-3m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 ITGA2B AQP2 IGDCC4 SLCO1C1 GALNT9

2.69e-061401246115bd770a9d5e6f007a9aa0eadf5dba46d500107
ToppCellfacs-Thymus-nan-3m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 ITGA2B AQP2 IGDCC4 SLCO1C1 GALNT9

2.69e-06140124622d126e80bf7d9c0ca6ec686b5cc66fa584a1ab6
ToppCellfacs-Thymus-nan-3m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 ITGA2B AQP2 IGDCC4 SLCO1C1 GALNT9

2.69e-06140124662d1ef8cb78618ed89cac7ec89d7f54de06a90c7
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SEZ6L2 SLCO4C1 MSLN SLC22A31

7.69e-061681246e20e1936573fdde78426d7a4eb45c458d5c4dbb4
ToppCell367C-Epithelial_cells-Epithelial-B_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SEZ6L2 SLCO4C1 MSLN SLC22A31

7.69e-06168124616b517e3159ad6e6d25fd48f7d5f46e77b2b318d
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 FGFR3 MSLN PCSK9 SLC22A31

8.80e-061721246a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 FGFR3 MSLN PCSK9 SLC22A31

8.80e-06172124626006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCell(7)_Epithelial-H_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PRSS8 SLC5A7 CLDN2 PROM2 KEL FGFR3

1.29e-0518412461f76b37c265b519171b767a52d48f31f0cdc4a3c
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA PRSS8 ITGA9 RNASE4 SLCO4C1 TMEM245

1.33e-051851246fd51fef8c69e34c72017d8371ab0a0d7be5701f2
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA PRSS8 ITGA9 RNASE4 SLCO4C1 TMEM245

1.33e-051851246bea26e369ae91006052b973cd89b4c49afa9e553
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell|TCGA-Uvea / Sample_Type by Project: Shred V9

HDAC3 SEC24D SFXN5 LHFPL2 TNFRSF1A VDAC1

1.37e-051861246e8580a2093eb7e50aad55ec7fada850d2fed8ae1
ToppCellPND03-Epithelial-Epithelial_Alveolar|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA PRSS8 RNASE4 SLCO4C1 TMEM245 MSLN

1.69e-0519312465dfa69a680a0859900141c40a446d217aaa747d3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA PRSS8 RNASE4 SLCO4C1 TMEM245 MSLN

1.69e-051931246ebea35704ac5d21e947ae094313cf2a5205e7014
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA PRSS8 SEZ6L2 RNASE4 PCSK9 SLC22A31

1.69e-051931246043dd0fc2f93e0bd1ca34ac3e196622b3e91df0f
ToppCellcellseq2-Epithelial-Epithelial_Alveolar-AT2-AT2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAPSA ITGA9 SLCO4C1 MSLN PCSK9 SLC22A31

1.74e-051941246df835578d86a49ae5af5632152fbab9548c0a448
ToppCellcellseq2-Epithelial-Epithelial_Alveolar|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAPSA ITGA9 SLCO4C1 MSLN PCSK9 SLC22A31

1.74e-0519412460715f2d55f4a6d2edda1b3dc52f12d25ce59eb10
ToppCellcellseq2-Epithelial-Epithelial_Alveolar-AT2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAPSA ITGA9 SLCO4C1 MSLN PCSK9 SLC22A31

1.74e-051941246a4f7cd507eba40985d82635bbae28c7f5703f883
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA RNASE4 SLCO4C1 FZD5 TMEM245 PCSK9

1.79e-051951246d9694db6bf239636d1335016878c98f6ee2eb0eb
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA PRSS8 SLCO4C1 TMEM245 PCSK9 SLC22A31

1.79e-0519512463e24570def013d5b0b1ef1d7a5ced7dfd922590b
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA SLCO4C1 CELF2 TMEM245 PCSK9 SLC22A31

1.85e-051961246006d783a530aa6e1e6545dcc2e6b00bb300fe070
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXA2R PCDH12 ITGA9 PLXNC1 LHFPL2 ATP2B4

1.90e-051971246d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXA2R PCDH12 ITGA9 PLXNC1 LHFPL2 ATP2B4

1.90e-051971246412091994196a06c2779b4c2cfed84be889a5f8d
ToppCellBiopsy_Control_(H.)-Epithelial-SCGB3A2+|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

PRSS8 CYP27C1 PROM2 FGFR3 MSLN SLC22A31

1.95e-0519812461fe51f4beca0eef4ff117e6edaa646e35c0f9629
ToppCellBiopsy_Other_PF-Epithelial-AT2|Biopsy_Other_PF / Sample group, Lineage and Cell type

NAPSA PRSS8 SEZ6L2 SLCO4C1 MSLN SLC22A31

2.01e-0519912469a65acfe9bf500db72142469cf17bf0973540001
ToppCellBiopsy_Control_(H.)-Epithelial-AT2|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

NAPSA PRSS8 SEZ6L2 SLCO4C1 TMEM245 SLC22A31

2.01e-0519912465323d49d3be980605b3e609b7f03bddba6e50e8a
ToppCelldistal-Epithelial-Club|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NAPSA PRSS8 CYP27C1 PROM2 MSLN SLC22A31

2.01e-051991246c63ccce1285352927fd8c4f7374ec5fff8d70cec
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA SEZ6L2 SLCO4C1 TMEM245 PCSK9 SLC22A31

2.01e-0519912462dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NAPSA PRSS8 SEZ6L2 SLCO4C1 MSLN SLC22A31

2.07e-05200124665c83a3f6ee2a10bcb5b95076696232c6373a7b4
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT2-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

NAPSA PRSS8 SEZ6L2 SLCO4C1 MSLN SLC22A31

2.07e-05200124640e969883bc302e8fbc6b6ab9814529dc1472902
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT2-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

NAPSA PRSS8 SEZ6L2 SLCO4C1 MSLN SLC22A31

2.07e-052001246ad9cdc82a647d379abc713a56db0e11bb6494106
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Astrocyte|GW12 / Sample Type, Dataset, Time_group, and Cell type.

ADAMTS4 WNT3 CDH23 IGDCC4 SFXN5 RNASE4

2.07e-052001246b9bd6c4381c92bfc1bfff9aa778a62a41d08f1ef
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CYP27C1 PFAS RNASE4 ADGRF3 PCSK9

3.68e-05134124572d7eec3aeb43319f3ef81bb5518fae8d8880136
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCAMP2 BTN3A1 LGALS9 LHFPL2 RPAP2

5.37e-0514512459743d68ba8bfef56fd9a979ab357c0e287eb5ae2
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

UTS2R MYO1A SLC5A7 CLDN2

5.45e-057412440d705c42e7741b861ba5a9f1af83b2c5c6f23fb6
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

UTS2R MYO1A SLC5A7 CLDN2

5.45e-05741244c49bda52aa4ead9483c2f27d63458034e75699bd
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAPSA KLHDC7B GRM5 CLDN2 IGDCC4

6.92e-051531245499670e716fc85ce76630fc813cec86f8419f2a1
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 AQP7 BCL11B GPR174 GPR62

7.82e-051571245cbb08d5c151f0622123276926a2a15bb7d271e90
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDH23 AQP7 BCL11B GPR174 GPR62

7.82e-05157124516581e2399a211633f870dce326c75ff4b6a5fe6
ToppCellControl-APC-like-Monocytes|Control / group, cell type (main and fine annotations)

TBXA2R ITGA2B SLCO1B1 SMO MFSD3

9.33e-0516312454bc80a2c741d462724b6f3902377d48c57478932
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SYN3 SEZ6L2 SLC22A31

9.61e-05164124585f53d184fa70e3eb1af655807f32b17ddbfb304
ToppCell368C-Epithelial_cells-Epithelial-A_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SYN3 SEZ6L2 SLC22A31

9.61e-051641245144ba070a1ede71684224cc6d4ead3b7e6a7b4c6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BCL11B GPR174 CELF2 GPR62 ADGRE5

9.61e-051641245649e42d9cfdec2f7771d1e938b516e46e7d07078
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BCL11B GPR174 CELF2 GPR62 ADGRE5

9.61e-051641245ba85f7b21ae34e285d286ada24715885ca6329f7
ToppCellnormal_Lung-Epithelial_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

NAPSA WNT3 GPR62 MSLN SLC22A31

9.61e-051641245fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA DNAJC22 PEX11A SLC22A12 SLC22A2

9.89e-051651245906321cb5f299d77436fb5540fd8c52d7532beca
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA DNAJC22 PEX11A SLC22A12 SLC22A2

9.89e-05165124502a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCAMP2 LGALS9 LHFPL2 SLC14A2 RPAP2

1.05e-041671245942134bbabe9972fae80cbc4ed4e94da52f55dc3
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

TCAF2 PTGFRN BCL11B SLIT1 RPAP2

1.05e-041671245ced6ed9b412739c6ced622523347c10295edbf53
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA AQP7 SLC22A12 SLCO4C1 SLC22A2

1.08e-041681245b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA PRSS8 UTS2R CLDN2 SLC22A12

1.11e-041691245daed9083ee05c220365200328c2c50047fe21efd
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAPSA PRSS8 ITGA9 RNASE4 SLCO4C1

1.14e-0417012456c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCelldroplet-Kidney-nan-3m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA SLC17A2 SLC24A3 SLC22A12 SLC22A2

1.14e-041701245dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAPSA SLC17A2 SEZ6L2 CLDN2 IGDCC4

1.20e-0417212450c2d0bb767e5ce089b42ad49e8b303a103de2d5c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAPSA SLC17A2 SEZ6L2 CLDN2 IGDCC4

1.20e-041721245eeed177a03c116e9815a8e086d24efc9643b16a4
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT2|E18.5-samps / Age Group, Lineage, Cell class and subclass

NAPSA PRSS8 ITGA9 RNASE4 SLCO4C1

1.23e-041731245f6e36ea98a9c669ff393d141455aaecef083f738
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

GRM1 ADCY8 SLCO4C1 GALNT9 VDAC1

1.23e-0417312457e3897868dd3f6e4974f593c60649a543ffc8693
ToppCellP03-Epithelial-epithelial_progenitor_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAPSA PRSS8 RNASE4 SLCO4C1 TMEM245

1.27e-04174124523c7fdfc73170cfc5cdee5bb7fbee0c8bbbbca07
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYN3 AQP7B ITGA9 AQP7 CELF2

1.27e-0417412453d4c05ea5719ca65e85d1f15198453034791087c
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)-|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 PROM2 MSLN SLC22A31

1.27e-041741245edf839d79ac58921f4e788f3b2cb2ae0d6af4b9e
ToppCell367C-Epithelial_cells-Epithelial-I_(AT1)|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 PROM2 MSLN SLC22A31

1.27e-04174124565539f69100db0b7d90b1b39ee15ab8281f86461
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA AQP2 SLC22A12 SLCO1C1 OSGIN1

1.30e-0417512457329ebb135fc4311ee9595729b62a5d152c9de8c
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBXA2R CYB5RL PCDH12 ITGA9 GPR146

1.30e-04175124543be63976da5ad0764d24d90919a77ce46068f52
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC24D SLCO4C1 SLIT1 CHPF2 SLC33A1

1.30e-04175124528b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCellP03-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAPSA PRSS8 RNASE4 SLCO4C1 TMEM245

1.30e-041751245a6d9ca35d3c4b4e3889d0a69b514f63ae630da6b
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA SLC17A2 SLC22A12 SLC22A2 SLC33A1

1.30e-041751245076ad81d6cbeea5512393d192af3ab5aa1f82975
ToppCellfacs-Kidney-nan-18m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA SLC17A2 SLC22A12 SLC22A2 SLC33A1

1.30e-041751245445ccb9744a3a9ff37164c532afbe769d306b6c8
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC24D SLCO4C1 SLIT1 CHPF2 SLC33A1

1.30e-041751245ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS4 GRIN1 SEZ6L2 VPS35 MFSD3

1.34e-041761245a9e77681bcd36c382d53eb6f771349d55f98d744
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA WNT3 SLC35E2B SLCO4C1 SLC22A31

1.37e-041771245ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA WNT3 SLC35E2B SLCO4C1 SLC22A31

1.37e-041771245d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA PRSS8 CLDN2 MSLN SLC22A31

1.41e-041781245f3b5eeca6081d65d48824b5d13e3b8eb5fdeb2dd
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TCAF2 UTS2R CYP27C1 SEZ6L2 IGDCC4

1.45e-04179124598c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCellCOVID-19-kidney-Mito-rich_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

BCL11B GPR174 CELF2 PLXNC1 ADGRE5

1.52e-0418112458448c2ad560cfd48bfe9dc1dd3a64373e6a622dd
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SYN3 GRM1 SEC24D SLIT1 ATP2B4

1.60e-04183124501ad18f198195ce341bae01a1c8c253cc4607766
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SLCO4C1 MSLN SLC22A31

1.65e-0418412450ba243cbf69b4fe6ae100a7f0314317bec38026c
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA PRSS8 RNASE4 SLCO4C1 TMEM245

1.65e-04184124549705c8fec565b16216bdf48e83e27521f52d99a
ToppCell367C-Epithelial_cells-Epithelial-A_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SLCO4C1 MSLN SLC22A31

1.65e-0418412452a8338e94937686a148b5433515700ca0f674058
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXA2R PCDH12 AGO3 PLXNC1 ATP2B4

1.69e-041851245742350093d90f96735dc73e3360cdd749bae63fd
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA PRSS8 RNASE4 SLCO4C1 TMEM245

1.69e-0418512452adb32096aa3473f8d417e5ce9e65264beca9b52
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA2B PCDH12 ITGA9 LGALS9 GPR146

1.69e-041851245fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH12 GPR146 PLXNC1 LHFPL2 ATP2B4

1.73e-0418612452cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TBXA2R PCDH12 LGALS9 GPR146 SLC4A11

1.73e-04186124586b218a400f9c64f92b050f00b49f09647b17437
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRM3 IGDCC4 RNASE4 SLCO1C1 GABRA3

1.73e-04186124594d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TBXA2R PCDH12 LGALS9 GPR146 SLC4A11

1.73e-041861245f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA2B PCDH12 ITGA9 LGALS9 GPR146

1.73e-0418612459d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDH12 GPR146 PLXNC1 LHFPL2 ATP2B4

1.73e-04186124590d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCellEpithelial-C_(AT2)|World / shred on cell class and cell subclass (v4)

NAPSA PRSS8 ITGA9 RNASE4 SLCO4C1

1.73e-041861245b7b1763fc52b4485d843a4a6727055e6c95ebad3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA ITGA9 RNASE4 SLCO4C1 TMEM245

1.77e-0418712456ab51e17a7782c2ae6394cad813dc3a2cde70c89
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35E2B AQP2 PROM2 SLC14A2 MSLN

1.77e-04187124522fd1959879705a8c1128faa9de66696c4e0b7e3
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA SLCO4C1 TMEM245 PCSK9 SLC22A31

1.77e-0418712457c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35E2B AQP2 PROM2 SLC14A2 MSLN

1.77e-0418712455fae538de481367cf6d9a2d52190d77b99f6922c
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SLCO4C1 MSLN SLC22A31

1.77e-04187124511670a85db87cbb3e78022a589632173604b0940
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC35E2B AQP2 PROM2 SLC14A2 MSLN

1.77e-0418712450526c0a818cf28fd5b6ff65fe260e3c3a4a98a2a
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|367C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SLCO4C1 MSLN SLC22A31

1.77e-0418712450277d4e54bd4d48f30241c2951a569209423fee8
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA ITGA9 RNASE4 SLCO4C1 TMEM245

1.77e-041871245e176b5b051690f840f3b12c8f7c4cc10cbe2bbae
ToppCell368C-Epithelial_cells-Epithelial-E_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

NAPSA PRSS8 SEZ6L2 MSLN SLC22A31

1.86e-0418912456f2322d017b74a1757c81d6e06f50ead8c3dd0cc
DrugAcamprosate

GRM1 GRM3 GRM5

1.49e-0651223DB00659
Drugaminocyclopentane

PFAS GRM1 GRM3 GRM5

2.86e-06191224CID000002906
Drugtrospium chloride

SLCO1B3 SLCO1B1 SLC22A2

2.97e-0661223ctd:C003330
Drugprobenecid

SLCO1B3 SLCO1B1 ADCY8 SLC22A12 SLCO1C1 SLCO4C1 KEL

4.53e-061231227CID000004911
Drugazetidine-2,4-dicarboxylic acid

GRM1 GRM3 GRM5

5.17e-0671223CID000005370
Drugdemethylphalloin

SLCO1B3 SLCO1B1 SLCO1C1

5.17e-0671223CID000114793
Drugcis-MCG-I

GRM1 GRM3 GRM5

8.24e-0681223CID003035584
DrugAC1L1EKQ

ITGA2B GRM1 GRM3 GRM5 ADCY8

8.64e-06521225CID000002834
DrugmM PEP

GRM1 GRM3 GRM5

1.23e-0591223CID005311462
DrugAC1N21PP

GRM1 GRM3 GRM5

1.23e-0591223CID004014619
Drug1,3-cyclopentanedicarboxylic acid

GRM1 GRM3 GRM5

1.23e-0591223CID000107216
Drug3,5-dihydroxyphenylglycine

GRIN1 GRM1 GRM5

1.75e-05101223ctd:C079215
DrugNS-105

GRM1 GRM3 GRM5

1.75e-05101223CID000198695
DrugAC1L63MU

TBXA2R GRM1 GRM3 GRM5 AQP2 PTGFRN ADCY8 RNASE4 CELF2 TNFRSF1A

1.81e-0534712210CID000285703
DrugEXP3174

TBXA2R UTS2R SLC22A12 SLC33A1

2.21e-05311224CID000108185
DrugPbCl4

GRM1 GRM3 GRM5

2.40e-05111223CID000123310
Drugcyclobutylene AP5

GRM1 GRM3 GRM5

2.40e-05111223CID000126582
DrugCC-I

FLII GRM1 GRM3 GRM5 TNFRSF1A

2.41e-05641225CID000448159
Drugxanthanoic acid

GRM1 GRM5

2.85e-0521222CID000065736
Drug(5-(3-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)isoxazol-5-yl)-2H-tetrazol-2-yl)acetic acid

SLCO1B3 SLCO1B1

2.85e-0521222ctd:C561635
Drugdopamine

FLII UTS2R GRIN1 GRM1 GRM3 GRM5 ADCY8 FCSK HDAC3 OXA1L TNFRSF1A GPR119 VDAC1 GABRA3

2.99e-0571512214CID000000681
Drug16-BAC

SYN3 TNFRSF1A VDAC1

3.19e-05121223CID000031202
DrugPolyphenols

ATP6V1E1 SYN3 SLC5A7 SLCO1B3 SLC24A3 GRIN1 ITGA2B PEX11A OXA1L SLCO1C1 SLC22A2

3.25e-0545212211ctd:D059808
Drugfelbamate

GRM1 GRM3 GRM5 ADGRE5 GABRA3

3.73e-05701225CID000003331
DrugMspg

GRM1 GRM3 GRM5

4.13e-05131223CID003964410
DrugMSOPPE

GRM1 GRM3 GRM5

4.13e-05131223CID005311463
DrugAC1NSKBB

GRM1 GRM3 GRM5

4.13e-05131223CID005311256
Drugcimetidine

SLCO1B3 SLCO1B1 ADCY8 SLC22A12 SLCO1C1 SLCO4C1 KEL

5.17e-051791227CID000002756
DrugMTPG

GRM1 GRM3 GRM5

5.23e-05141223CID005311456
Drug2-methyl-6-styrylpyridine

GRM1 GRM3 GRM5

5.23e-05141223CID000235382
DrugL-quisqualic acid

NAPSA GRM1 GRM3 GRM5 ADCY8 ADGRE5 GABRA3

5.36e-051801227CID000001209
Drug4-aminopyrrolidine-2,4-dicarboxylate

TBXA2R GRM1 GRM3 GRM5

5.58e-05391224CID003331970
Drugthiourea

GRM1 GRM3 GRM5 RNASE4 KEL SLC14A2

6.66e-051281226CID002723790
Drugpentylenetetrazol

FLII GRM1 GRM3 GRM5 ADGRE5 GABRA3

7.26e-051301226CID000005917
Drugethylglutamate

GRM1 GRM3 GRM5

7.99e-05161223CID000014241
Drug2-PMPA

GRM1 GRM3 GRM5

7.99e-05161223CID010130754
DrugJoro spider toxin

GRM1 GRM3 GRM5 VDAC1

8.24e-05431224CID000119582
Drugfenobam

GRM1 GRM5

8.51e-0531222CID000162834
DrugDiethylstilbestrol [56-53-1]; Up 200; 15uM; PC3; HT_HG-U133A

WNT3 DNAJC22 PCDH12 GRM1 GRM3 TRIM3 SLCO1C1

8.58e-0519412273812_UP
DrugTinidazole [19387-91-8]; Up 200; 16.2uM; MCF7; HT_HG-U133A

SLC24A3 ITGA2B GRM1 ITGA9 BTN3A1 KEL ATP2B4

9.15e-0519612274370_UP
DrugMethylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A

TBXA2R SYN3 TAS2R1 SLCO1C1 PLXNC1 KEL ATP2B4

9.44e-0519712274113_UP
DrugAmyleine hydrochloride [532-59-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A

TBXA2R SYN3 ITGA2B TRIM3 TAS2R1 SLCO1C1 ATP2B4

9.44e-0519712271491_UP
Drug3HPG

GRM1 GRM3 GRM5

9.66e-05171223CID000001217
DrugHalcinonide [3093-35-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A

SLC17A2 TPRA1 SEZ6L2 TRIM3 SEC24D PLXNC1 ADGRE5

9.75e-0519812276040_DN
Drug7-chlorokynurenic acid

GRIN1 GRM1 GRM3 GRM5

9.86e-05451224CID000001884
DrugMeprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A

TBXA2R GRM1 GRM3 SLCO1B1 BTN3A1 PLXNC1 KEL

1.01e-0419912273544_UP
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; PC3; HT_HG-U133A

TBXA2R SLC17A2 ITGA2B BTN3A1 CIC TAS2R1 GABRA3

1.04e-0420012274605_UP
Drugsulfinpyrazone

SLCO1B3 SLCO1B1 SLC22A12 SLCO1C1 SLCO4C1

1.06e-04871225CID000005342
Drugacromelic acid A

GRM1 GRM3 GRM5

1.15e-04181223CID000108086
DrugLY382884

GRM1 GRM3 GRM5

1.37e-04191223CID000656723
DrugAC1Q5UBL

GRM1 GRM3 GRM5 ADCY8 ADGRE5 GABRA3

1.38e-041461226CID000005466
Drug4-carboxy-3-hydroxyphenylglycine

GRM1 GRM3 GRM5

1.60e-04201223CID000001297
DrugDihydromicrocystin Lr

SLCO1B3 SLCO1B1

1.70e-0441222CID006441227
Drugrifamycin SV

SLCO1B3 SLCO1B1

1.70e-0441222ctd:C023808
DrugCbpg

GRM1 GRM5

1.70e-0441222CID005311040
DrugOxonic Acid

LGALS9 SLC22A2

1.70e-0441222ctd:D010094
DrugE 3040

SLCO1B1 SLC22A12

1.70e-0441222ctd:C095803
Drugmicrocystin-LF

SLCO1B3 SLCO1B1

1.70e-0441222ctd:C524165
Drug3,4-dihydroxyphenylglycine

GRM1 GRM3 GRM5

1.86e-04211223CID000027915
DrugN-Ac-D-E

GRIN1 GRM1 GRM3 GRM5

1.88e-04531224CID000005255
DiseaseX-21467 measurement

SLCO1B3 SLCO1B1 SLCO1C1

5.28e-0691193EFO_0020007
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE, DIGENIC

SLCO1B3 SLCO1B1

1.61e-0521192C4016905
DiseaseRotor Syndrome

SLCO1B3 SLCO1B1

1.61e-0521192C0220991
DiseaseRotor syndrome

SLCO1B3 SLCO1B1

1.61e-0521192cv:C0220991
DiseaseHYPERBILIRUBINEMIA, ROTOR TYPE

SLCO1B3 SLCO1B1

1.61e-0521192237450
DiseaseAttention Deficit Disorder

GRM1 GRM5 CIC

9.31e-05221193C0041671
DiseaseMinimal Brain Dysfunction

GRM1 GRM5 CIC

9.31e-05221193C1321905
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM1 GRM3 GRM5

1.07e-04231193C0393672
DiseaseEpilepsy, Lateral Temporal

GRM1 GRM3 GRM5

1.07e-04231193C0393682
DiseaseUncinate Epilepsy

GRM1 GRM3 GRM5

1.07e-04231193C0014558
DiseaseEpilepsy, Temporal Lobe

GRM1 GRM3 GRM5

1.07e-04231193C0014556
DiseaseAttention deficit hyperactivity disorder

GRM1 GRM5 CIC

1.22e-04241193C1263846
Diseasebilirubin metabolic disorder (implicated_via_orthology)

SLCO1B3 SLCO1B1

1.60e-0451192DOID:2741 (implicated_via_orthology)
Diseaseovarian cancer (is_marker_for)

PRSS8 SLCO1B3 HDAC3 TNFRSF1A

1.68e-04681194DOID:2394 (is_marker_for)
Diseasebilirubin metabolic disorder (is_implicated_in)

SLCO1B3 SLCO1B1

2.39e-0461192DOID:2741 (is_implicated_in)
Diseasedeoxycholic acid glucuronide measurement

SLCO1B3 SLCO1B1

4.44e-0481192EFO_0800575
Diseasehexadecenedioate (C16:1-DC) measurement

SLCO1B3 SLCO1B1

5.70e-0491192EFO_0800562
Diseasehearing impairment

MYO1A CDH23 FGFR3 SLC33A1

6.78e-04981194C1384666
DiseaseEpilepsy

PCDH12 GRM1 FGFR3 VDAC1

1.01e-031091194C0014544
Diseasegranulins measurement

CDH23 ITGA2B

1.04e-03121192EFO_0008141
Diseasealopecia areata

PLXNC1 TNFRSF1A VDAC1

1.09e-03501193EFO_0004192
Diseaseglycochenodeoxycholate glucuronide (1) measurement

SLCO1B3 SLCO1B1

1.22e-03131192EFO_0800474
Diseasecolon carcinoma (is_marker_for)

SLCO1B3 TNFRSF1A

1.22e-03131192DOID:1520 (is_marker_for)
Diseasevisceral:abdominal adipose tissue ratio measurement

ADCY8 SLC14A2 ATP2B4

1.22e-03521193EFO_0803318
Diseaseecosanoids measurement

SLCO1B3 SLCO1B1 SLCO1C1

1.44e-03551193EFO_0020044
Diseaseresponse to statin, LDL cholesterol change measurement

SLCO1B1 PCSK9

1.64e-03151192EFO_0007804, GO_0036273
Diseasepancreatic ductal carcinoma (is_implicated_in)

SMO MSLN

1.87e-03161192DOID:3587 (is_implicated_in)
Diseasenon-word reading

SFXN5 BCL11B SLIT1

2.54e-03671193EFO_0005299
Diseasekidney failure (biomarker_via_orthology)

SLCO4C1 SLC22A2

2.64e-03191192DOID:1074 (biomarker_via_orthology)
Diseaseage at menarche

SLC24A3 ECPAS ADCY8 TMEM245 GALNT9 SLIT1 RBM6 SLC14A2

2.86e-035941198EFO_0004703
Diseasechemokine (C-C motif) ligand 27 measurement

SLCO1B3 AQP7 SLCO1C1

2.88e-03701193EFO_0008082
Diseasedisease

SLC22A2 SLC14A2

3.22e-03211192EFO_0000408
DiseaseBipolar Disorder

SYN3 GRIN1 ITGA9 GRM3 GRM5 ADCY8 GABRA3

3.27e-034771197C0005586
Diseaseprogranulin measurement

CDH23 ITGA2B

3.53e-03221192EFO_0004625
DiseaseIGF-1 measurement

OR5T1 PRSS8 VPS13C GRM5 SLC22A2 SLIT1 OSGIN1

3.71e-034881197EFO_0004627
DiseaseMental Depression

GRM1 ADCY8 SLCO1C1 TNFRSF1A GABRA3

3.74e-032541195C0011570

Protein segments in the cluster

PeptideGeneStartEntry
SLIGLGYTQTLKPGI

VDAC1

241

P21796
GVYSQILLELPALAG

URB2

1156

Q14146
LYVLQGIPLGLAGSI

SLC33A1

81

O00400
LPGQYSLAAVVLGLV

ADCY8

1186

P40145
SIAGLLYALVQLGQP

B3GAT3

16

O94766
GLAGVTLGLYLPQGQ

ADGRF3

896

Q8IZF5
IGPLVGAILGSLLYN

AQP2

206

P41181
TGLGGLTPQYLALLQ

CELF2

241

O95319
LVIGGYLIPKGTQLA

CYP27C1

426

Q4G0S4
LPVLLLLLGGAGYFL

BTN3A1

256

O00481
ANPGIVGLLLTTLEY

ARMC2

626

Q8NEN0
ENIPLLIAGVIGGSY

GRM3

136

Q14832
CLIGYGVPLLIVGVS

ADGRE5

656

P48960
LYVVDLLLSGGQPVL

DNHD1

2371

Q96M86
NTYSGLQLIIVILPG

AGO3

511

Q9H9G7
GLNGLVTYTLLDLVP

CDH23

2326

Q9H251
IDGVSLLLPSLGYNG

FAM193A

1166

P78312
YGDLLPADGILIQGN

ATP2B4

216

P23634
PAGTGQTLLLQALVY

IGDCC4

1096

Q8TDY8
LGLQLVGPYDILAGK

HPF1

76

Q9NWY4
QLLLGLLGPGGYLFL

PCDH12

6

Q9NPG4
GRSLPVLGLGLLLYS

MFSD10

356

Q14728
FGPIYLLALLGNGAL

OR52W1

36

Q6IF63
VGLGLGYLELPQINY

FLII

731

Q13045
TNLGVVTPLGYNGLL

GRM5

736

P41594
FALPALLLLGAYGGI

GPR62

181

Q9BZJ7
YAGPLMLGLLLAVIG

MAGT1

186

Q9H0U3
GSPLGGVITNYLLEK

MYO1A

171

Q9UBC5
VRYSADGLLQLGPLG

GALNT9

501

Q9HCQ5
PLLGASLGGIIYLVF

AQP7P3

261

A6NL99
PLLGASLGGIIYLVF

AQP7B

266

A0A075B734
ILGGLYPSKSILLSG

LGALS9

231

O00182
YIGLLQQLLAGVGGL

ECPAS

656

Q5VYK3
GPLVVLLPLAGGYSR

PCSK9

281

Q8NBP7
GSPYGLQLNEIGLEL

PLXNC1

1246

O60486
GSLGLGLIIIQHGPY

PDZD9

36

Q8IXQ8
GLLGDQGLPGVFVLY

ERGIC3

311

Q9Y282
LLGVGNSLLNPLIYA

GPR119

266

Q8TDV5
YGELLLLAAGTGLAP

CYB5RL

181

Q6IPT4
GIAGLFLILGLILYP

LHFPL2

141

Q6ZUX7
ILFLINILPGTTGQG

GABRA3

16

P34903
LQGGIPNGYLVLDLS

MSLN

586

Q13421
VPVVAPLLGAYLGGI

AQP7

256

O14520
YTVILVPGLIGNILA

GPR174

26

Q9BXC1
LGSYTPVGLIQNLLE

OXA1L

116

Q15070
LYLVQGLPYGLQSGL

MFSD3

11

Q96ES6
GLPYGLQSGLLPVLL

MFSD3

16

Q96ES6
FNIPLLVLGGGGYTV

HDAC3

286

O15379
IGSNVFDILIGLGLP

SLC24A3

546

Q9HC58
FYLTLIVGLGGPVGN

MRGPRG

16

Q86SM5
LLLALVVAGIPAGAY

ITGA9

16

Q13797
IYLFTLIGNLGLVVP

OR5T1

46

Q8NG75
LIGNLGLVVPIIGDF

OR5T1

51

Q8NG75
PLAYELGGAVLGLAV

FCSK

726

Q8N0W3
RGFVLGPLVLYLLVG

FZD5

401

Q13467
GLTVQYLGQAPELLG

ADAMTS4

106

O75173
VSLYPLGGLFGALLA

SLC2A11

71

Q9BYW1
NVGLGALPQYGELLA

BCL11B

601

Q9C0K0
GVLNPELGYDALLVG

BBS2

81

Q9BXC9
GVIPVIYYSVLLGLG

GPR142

156

Q7Z601
LQLVGYILGLLGLLG

CLDN2

6

P57739
AVLGVLVLPSLYQGG

KLHDC7B

281

Q96G42
GAAVLGLLILAYPFL

KNCN

46

A6PVL3
LLGACTQGGPLYVLV

FGFR3

541

P22607
LLGLVVGVPVGLCYN

GPR146

31

Q96CH1
LGVVAPLGYNGLLIM

GRM1

751

Q13255
YIVALPLAVGLGVLL

DNAJC22

106

Q8N4W6
YGTVPVLSGLAALLL

SLC22A12

501

Q96S37
GLASLLLLAGAQYLP

SLC22A31

406

A6NKX4
TVGLLVLAGVAYALP

SLC22A2

246

O15244
IVGNGPSGICLSYLL

OSGIN1

21

Q9UJX0
ALPLGILYLLALVGN

OR52L1

46

Q8NGH7
ALPLGILYLLALVGN

OR52L2P

46

Q8NGH6
LGLVSLLRGVLYIGP

OR52M1

146

Q8NGK5
YPLLIGVGLSTVIGL

PTGFRN

831

Q9P2B2
QAPIGYSLSLILGGL

SLC5A7

86

Q9GZV3
IQPTGILHLGNYLGA

WARS2

41

Q9UGM6
VIGLQYGGLPAVNSL

SYN3

181

O14994
KVVNPLIGLLGEYGG

RBM6

896

P78332
GGLLYALFSGQPLVI

SLC4A11

401

Q8NBS3
GGLLYIIVPQNSKLG

TCAF1

611

Q9Y4C2
GGLLYVIVPKGSQLG

TCAF2

611

A6NFQ2
IYIIQLVGIPGLGDS

SCAMP2

231

O15127
GGGVFLIPYVLIALV

SLC6A8

86

P48029
QLGIYKSNPGIIGLG

PEX11A

211

O75192
LPLGLVIVLGSGVYI

SEZ6L2

851

Q6UXD5
LGAPSLLLTGTQLYG

ITGA2B

371

P08514
VLGPGQLGAVAILLY

PRSS8

6

Q16651
ALGGILAPIYFGALI

SLCO1B1

581

Q9Y6L6
SLGLVPQLTGGTLYK

SEC24D

646

O94855
LGKAGGITQVQYILP

CIC

816

Q96RK0
ALLTLLLVYGPREGG

CHPF2

521

Q9P2E5
KVVNLGIPTLLYGLG

C15orf61

111

A6NNL5
IGIYPSGHSLILILG

TAS2R1

266

Q9NYW7
TLLGLGLVQPSYGQD

RNASE4

16

P34096
YAGILALLNLLQGLG

TPRA1

231

Q86W33
GLPTYTLAVQGISGL

TSR1

181

Q2NL82
YPVALLLLVATLGLG

ZP1

11

P60852
VIAGLYLLLVPTAGL

PROM2

111

Q8N271
YPLLAAVGSLGQVLQ

PROM2

246

Q8N271
GLLVPLQITLGDIYT

RPAP2

516

Q8IXW5
QLLLGAGGTPLYTLG

SLCO4C1

236

Q6ZQN7
LGPAIGYVLGGQLLT

SLCO4C1

276

Q6ZQN7
AGNIIPRLYLLITVG

VPS35

101

Q96QK1
LLYVALSPGQHRLGG

PFAS

851

O15067
SLGGIPGYILLLRCI

SLCO1C1

566

Q9NYB5
TLGGILAPIYFGALI

SLCO1B3

581

Q9NPD5
GIILTLIPSGYLAGI

SLC17A2

101

O00624
GLLLGGTRVLAGYPI

WNT3

11

P56703
LVLGLDVLGNPFGLI

VPS13C

3416

Q709C8
LGEYTGLLVNLSLIP

SLC35E2B

191

P0CK96
APIGLVLIVGGYFLI

SMO

406

Q99835
YYLGLEGAIIGPILL

TMEM245

816

Q9H330
AGPGLLIGLLYARLA

UTS2R

221

Q9UKP6
QVLGVIGYSLLPLIV

YIPF4

166

Q9BSR8
LDGLVLQGLYQLLEP

ATP6V1E1

116

P36543
LALGLLPLLGVGRYT

TBXA2R

161

P21731
GYIPFGTPIVVGLLL

SFXN5

111

Q8TD22
DLPRGVFGGLYTLQL

SLIT1

371

O75093
LLLQAIPVGVGQVYG

SLC14A2

281

Q15849
LELLVGIYPSGVIGL

TNFRSF1A

16

P19438
ATELLGLGGLLYKAP

ZMYM3

76

Q14202
IVLTPGTYGLSNALL

TANGO2

146

Q6ICL3
GELLLSVLLYGQPVR

TRIM3

396

O75382
PLIPLYLLVGGIVGT

TMEM272

51

A0A1B0GTI8
LTYLNQLGTLLGGDP

KEL

251

P23276
SYVGLVLVLLRGLPG

N4BP2

436

Q86UW6
AAIGGIPLLAGEYII

NAPSA

301

O96009
YAPDGILGLQLINGK

GRIN1

261

Q05586