Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type divalent copper transporter activity	ATP7A ATP7B	1.18e-05	2	69	2	GO:0043682
GeneOntologyMolecularFunction	P-type monovalent copper transporter activity	ATP7A ATP7B	1.18e-05	2	69	2	GO:0140581
GeneOntologyMolecularFunction	copper ion transmembrane transporter activity	ATP7A ATP7B	3.25e-04	8	69	2	GO:0005375
GeneOntologyBiologicalProcess	positive regulation of microtubule binding	PPP2CA PPP2CB ABL1	3.89e-07	5	71	3	GO:1904528
GeneOntologyBiologicalProcess	regulation of microtubule binding	PPP2CA PPP2CB ABL1	3.23e-06	9	71	3	GO:1904526
GeneOntologyBiologicalProcess	positive regulation of protein binding	STK4 PPP2CA PPP2CB VTN ABL1	1.11e-05	85	71	5	GO:0032092
GeneOntologyBiologicalProcess	copper ion export	ATP7A ATP7B	3.50e-05	3	71	2	GO:0060003
GeneOntologyBiologicalProcess	response to lead ion	PPP2CA PPP2CB ATP7A	8.51e-05	25	71	3	GO:0010288
GeneOntologyCellularComponent	spindle pole	PPP2CA PPP2CB PLK2 PLK5 BIRC6 PLK3	7.54e-05	205	72	6	GO:0000922
GeneOntologyCellularComponent	P-body	PSMA6 EDC4 CNOT3 APOBEC3F	4.26e-04	102	72	4	GO:0000932
GeneOntologyCellularComponent	Golgi lumen	VTN VCAN MMP14 MMP16	5.48e-04	109	72	4	GO:0005796
HumanPheno	Osteomalacia	PHEX ATP7A ATP7B GATM	8.65e-06	27	26	4	HP:0002749
MousePheno	decreased creatine level	ATP7A GATM SLC4A11	7.10e-07	5	59	3	MP:0010062
MousePheno	abnormal creatine level	ATP7A GATM SLC4A11	5.89e-06	9	59	3	MP:0010060
MousePheno	abnormal kidney copper level	ATP7A ATP7B	1.75e-05	2	59	2	MP:0010242
MousePheno	increased kidney copper level	ATP7A ATP7B	1.75e-05	2	59	2	MP:0010243
MousePheno	increased brain copper level	ATP7A ATP7B	1.75e-05	2	59	2	MP:0011214
MousePheno	dilated respiratory conducting tube	ATP7A NPAS3 MMP14	4.66e-05	17	59	3	MP:0010856
MousePheno	decreased liver copper level	ATP7A ATP7B	5.24e-05	3	59	2	MP:0003067
MousePheno	decreased circulating copper level	ATP7A ATP7B	5.24e-05	3	59	2	MP:0006349
MousePheno	abnormal cranium size	PHEX ABL1 GLDC MMP14 MMP16	5.40e-05	97	59	5	MP:0010031
MousePheno	increased copper level	ATP7A ATP7B	1.05e-04	4	59	2	MP:0014539
MousePheno	decreased urine creatine level	GATM SLC4A11	1.05e-04	4	59	2	MP:0030633
MousePheno	abnormal urine creatine level	GATM SLC4A11	1.05e-04	4	59	2	MP:0030631
MousePheno	abnormal circulating copper level	ATP7A ATP7B	1.05e-04	4	59	2	MP:0006348
MousePheno	decreased copper level	ATP7A ATP7B	1.74e-04	5	59	2	MP:0014540
MousePheno	abnormal brain copper level	ATP7A ATP7B	1.74e-04	5	59	2	MP:0011213
MousePheno	abnormal amino acid derivative level	SLC25A32 ATP7A GLDC GATM SLC4A11	1.80e-04	125	59	5	MP:0021145
MousePheno	abnormal liver copper level	ATP7A ATP7B	2.60e-04	6	59	2	MP:0003065
MousePheno	abnormal respiratory conducting tube morphology	ATP7A HGSNAT NPAS3 MMP14	3.40e-04	79	59	4	MP:0004391
MousePheno	decreased cranium height	PHEX ABL1 MMP14	3.56e-04	33	59	3	MP:0008525
MousePheno	dilated pulmonary alveolar duct	ATP7A MMP14	3.63e-04	7	59	2	MP:0010908
MousePheno	increased glycine level	SLC25A32 GLDC	3.63e-04	7	59	2	MP:0030658
Domain	DUF3377	MMP24 MMP14 MMP16	1.84e-07	4	68	3	PF11857
Domain	-	PLK2 PLK5 PLK3	1.84e-07	4	68	3	3.30.1120.30
Domain	POLO_box_1	PLK2 PLK5 PLK3	1.84e-07	4	68	3	IPR033701
Domain	Pept_M10A_metallopeptidase_C	MMP24 MMP14 MMP16	1.84e-07	4	68	3	IPR021805
Domain	Hemopexin_CS	MMP24 VTN MMP14 MMP16	3.69e-07	17	68	4	IPR018486
Domain	POLO_box_dom	PLK2 PLK5 PLK3	4.59e-07	5	68	3	IPR000959
Domain	Hemopexin-like_dom	MMP24 VTN MMP14 MMP16	1.35e-06	23	68	4	IPR000585
Domain	Hemopexin-like_repeat	MMP24 VTN MMP14 MMP16	1.35e-06	23	68	4	IPR018487
Domain	Hemopexin	MMP24 VTN MMP14 MMP16	1.35e-06	23	68	4	PF00045
Domain	HEMOPEXIN	MMP24 VTN MMP14 MMP16	1.35e-06	23	68	4	PS00024
Domain	-	MMP24 VTN MMP14 MMP16	1.35e-06	23	68	4	2.110.10.10
Domain	HEMOPEXIN_2	MMP24 VTN MMP14 MMP16	1.35e-06	23	68	4	PS51642
Domain	HX	MMP24 VTN MMP14 MMP16	1.35e-06	23	68	4	SM00120
Domain	HMA_Cu_ion-bd	ATP7A ATP7B	1.31e-05	2	68	2	IPR006122
Domain	P-typ_ATPase_IB	ATP7A ATP7B	1.31e-05	2	68	2	IPR027256
Domain	Pept_M10A_stromelysin-type	MMP24 MMP14 MMP16	3.62e-05	18	68	3	IPR016293
Domain	POLO_box_2	PLK2 PLK3	3.91e-05	3	68	2	IPR033695
Domain	Heavy-metal-associated_CS	ATP7A ATP7B	3.91e-05	3	68	2	IPR017969
Domain	PG_binding_1	MMP24 MMP14 MMP16	5.03e-05	20	68	3	PF01471
Domain	Peptidoglycan-bd-like	MMP24 MMP14 MMP16	5.03e-05	20	68	3	IPR002477
Domain	M10A_MMP	MMP24 MMP14 MMP16	7.76e-05	23	68	3	IPR033739
Domain	Pept_M10A	MMP24 MMP14 MMP16	7.76e-05	23	68	3	IPR021190
Domain	HMA	ATP7A ATP7B	7.80e-05	4	68	2	PF00403
Domain	POLO_box	PLK2 PLK3	7.80e-05	4	68	2	PF00659
Domain	POLO_BOX	PLK2 PLK3	7.80e-05	4	68	2	PS50078
Domain	HMA_2	ATP7A ATP7B	7.80e-05	4	68	2	PS50846
Domain	HMA_1	ATP7A ATP7B	7.80e-05	4	68	2	PS01047
Domain	Peptidase_M10	MMP24 MMP14 MMP16	8.84e-05	24	68	3	PF00413
Domain	ZnMc	MMP24 MMP14 MMP16	1.58e-04	29	68	3	SM00235
Domain	Peptidase_Metallo	MMP24 MMP14 MMP16	1.58e-04	29	68	3	IPR006026
Domain	MetalloPept_cat_dom	PHEX MMP24 MMP14 MMP16	2.17e-04	81	68	4	IPR024079
Domain	-	PHEX MMP24 MMP14 MMP16	2.17e-04	81	68	4	3.40.390.10
Domain	HMA_dom	ATP7A ATP7B	2.71e-04	7	68	2	IPR006121
Domain	CYSTEINE_SWITCH	MMP24 MMP14 MMP16	4.46e-04	41	68	3	PS00546
Domain	ZINC_PROTEASE	PHEX MMP24 MMP14 MMP16	4.49e-04	98	68	4	PS00142
Domain	Pept_M10_metallopeptidase	MMP24 MMP14 MMP16	5.13e-04	43	68	3	IPR001818
Domain	Ser/Thr-sp_prot-phosphatase	PPP2CA PPP2CB	9.93e-04	13	68	2	IPR006186
Domain	SER_THR_PHOSPHATASE	PPP2CA PPP2CB	9.93e-04	13	68	2	PS00125
Domain	PP2Ac	PPP2CA PPP2CB	9.93e-04	13	68	2	SM00156
Domain	Pept_M10A_Zn_BS	MMP14 MMP16	1.33e-03	15	68	2	IPR021158
Domain	TPR-like_helical_dom	UTP6 RAPSN SEL1L3 CDC27 KDM6A	1.59e-03	233	68	5	IPR011990
Domain	TPR_1	RAPSN CDC27 KDM6A	4.33e-03	90	68	3	PF00515
Domain	TPR_1	RAPSN CDC27 KDM6A	4.33e-03	90	68	3	IPR001440
Domain	Calcineurin-like_PHP_ApaH	PPP2CA PPP2CB	4.64e-03	28	68	2	IPR004843
Domain	Metallophos	PPP2CA PPP2CB	4.64e-03	28	68	2	PF00149
Domain	Metallo-depent_PP-like	PPP2CA PPP2CB	5.32e-03	30	68	2	IPR029052
Domain	-	PPP2CA PPP2CB	5.32e-03	30	68	2	3.60.21.10
Pathway	REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1	PPP2CA PPP2CB PRIM1	6.99e-06	10	56	3	MM14509
Pathway	REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1	PPP2CA PPP2CB PRIM1	1.65e-05	13	56	3	M1015
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	PLK2 PLK3 CNOT3	4.64e-05	18	56	3	MM15336
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_ADDITIONAL_CELL_CYCLE_GENES_WHOSE_EXACT_ROLE_IN_THE_P53_PATHWAY_REMAIN_UNCERTAIN	PLK2 PLK3 CNOT3	7.51e-05	21	56	3	M27634
Pathway	REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION	PPP2CA PPP2CB PRIM1	8.67e-05	22	56	3	M6768
Pathway	REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	PPP2CA PPP2CB CCNB2	1.28e-04	25	56	3	M808
Pathway	REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	PPP2CA PPP2CB CCNB2	1.28e-04	25	56	3	MM15379
Pathway	REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	PPP2CA PPP2CB ABL1 PRIM1 PSMA6	1.62e-04	130	56	5	MM15146
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP24 MMP14 MMP16	2.02e-04	29	56	3	MM15981
Pathway	WP_MATRIX_METALLOPROTEINASES	MMP24 MMP14 MMP16	2.23e-04	30	56	3	M39652
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP24 MMP14 MMP16	2.98e-04	33	56	3	M26976
Pathway	REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	PPP2CA PPP2CB ABL1 PRIM1 PSMA6	3.05e-04	149	56	5	M848
Pathway	REACTOME_PP2A_MEDIATED_DEPHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS	PPP2CA PPP2CB	3.21e-04	7	56	2	M26992
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES	PLK2 PLK3 CNOT3	3.26e-04	34	56	3	MM15325
Pathway	WP_RETINOBLASTOMA_GENE_IN_CANCER	ABL1 CCNB2 PRIM1 RRM1	4.43e-04	90	56	4	M39678
Pathway	REACTOME_ACTIVATION_OF_MATRIX_METALLOPROTEINASES	MMP24 MMP14 MMP16	4.54e-04	38	56	3	MM14611
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MMP24 VTN PSG4 VCAN MMP14 MMP16	5.35e-04	258	56	6	MM14572
Pathway	REACTOME_TGFBR3_PTM_REGULATION	MMP14 MMP16	6.83e-04	10	56	2	MM17232
Pathway	REACTOME_MASTL_FACILITATES_MITOTIC_PROGRESSION	PPP2CA PPP2CB	6.83e-04	10	56	2	M27176
Pathway	REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	PPP2CA PPP2CB ABL1	7.01e-04	44	56	3	MM15377
Pathway	REACTOME_G1_S_TRANSITION	PPP2CA PPP2CB PRIM1 PSMA6	7.65e-04	104	56	4	MM15376
Pathway	WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION	MMP24 MMP14 MMP16	7.99e-04	46	56	3	M46450
Pathway	REACTOME_TGFBR3_PTM_REGULATION	MMP14 MMP16	8.33e-04	11	56	2	M48251
Pathway	REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	PPP2CA PPP2CB ABL1	8.51e-04	47	56	3	M29724
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES	PLK2 PLK3 CNOT3	9.61e-04	49	56	3	M27614
Pathway	REACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM	PPP2CA PPP2CB	9.97e-04	12	56	2	M27950
Pathway	KEGG_OOCYTE_MEIOSIS	PPP2CA PPP2CB CCNB2 CDC27	1.04e-03	113	56	4	M16817
Pathway	REACTOME_ERKS_ARE_INACTIVATED	PPP2CA PPP2CB	1.18e-03	13	56	2	MM14811
Pathway	REACTOME_ERKS_ARE_INACTIVATED	PPP2CA PPP2CB	1.18e-03	13	56	2	M8410
Pathway	WP_DOPAMINE_METABOLISM	PPP2CA PPP2CB	1.18e-03	13	56	2	M39622
Pathway	REACTOME_LGI_ADAM_INTERACTIONS	CACNG8 LGI2	1.37e-03	14	56	2	MM15277
Pathway	REACTOME_LGI_ADAM_INTERACTIONS	CACNG8 LGI2	1.37e-03	14	56	2	M27564
Pathway	REACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS	PPP2CA PPP2CB	1.57e-03	15	56	2	M27407
Pathway	REACTOME_INNATE_IMMUNE_SYSTEM	PPP2CA PPP2CB IGHV3-33 VTN ABL1 ATP7A PSG4 FCN2 PSMA6 HGSNAT CD300E	1.61e-03	995	56	11	MM14661
Pathway	PID_P53_REGULATION_PATHWAY	PPP2CA ABL1 CSNK1G1	1.65e-03	59	56	3	M261
Pathway	KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE	PPP2CA PPP2CB	1.79e-03	16	56	2	M47870
Pathway	REACTOME_DARPP_32_EVENTS	PPP2CA PPP2CB	1.79e-03	16	56	2	MM14699
Pathway	REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING	PPP2CA PPP2CB	1.79e-03	16	56	2	MM14541
Pathway	REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING	PPP2CA PPP2CB	1.79e-03	16	56	2	M514
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	PJA2 PPP2CA PPP2CB IGHV3-33 RBBP6 PSMA6 CD207 CDC27 CD300E	1.95e-03	719	56	9	MM14540
Pathway	REACTOME_PLATELET_SENSITIZATION_BY_LDL	PPP2CA PPP2CB	2.03e-03	17	56	2	MM15096
Pathway	REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION	PPP2CA CCNB2	2.03e-03	17	56	2	MM14920
Pathway	REACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE	PPP2CA PPP2CB	2.03e-03	17	56	2	M27083
Pathway	REACTOME_PLATELET_SENSITIZATION_BY_LDL	PPP2CA PPP2CB	2.03e-03	17	56	2	M919
Pathway	REACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE	PPP2CA PPP2CB	2.28e-03	18	56	2	MM14759
Pathway	REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	PPP2CA PPP2CB CCNB2 PSMA6 CDC27	2.32e-03	234	56	5	MM14898
Pathway	REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	PPP2CA PPP2CB CCNB2 PSMA6 CDC27	2.40e-03	236	56	5	M27185
Pathway	REACTOME_INITIATION_OF_NUCLEAR_ENVELOPE_NE_REFORMATION	PPP2CA CCNB2	2.54e-03	19	56	2	M29617
Pathway	KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY	PPP2CA PPP2CB	2.54e-03	19	56	2	M47525
Pathway	REACTOME_ERK_MAPK_TARGETS	PPP2CA PPP2CB	2.54e-03	19	56	2	MM14780
Pubmed	Changes in the expression of membrane type-matrix metalloproteinases genes (MMP14, MMP15, MMP16, MMP24) during treatment and their potential impact on the survival of patients with non-small cell lung cancer (NSCLC).	MMP24 MMP14 MMP16	3.40e-08	4	72	3	35062057
Pubmed	mRNA expression of the five membrane-type matrix metalloproteinases MT1-MT5 in human prostatic cell lines and their down-regulation in human malignant prostatic tissue.	MMP24 MMP14 MMP16	8.48e-08	5	72	3	12661033
Pubmed	MT3-MMP Promotes Excitatory Synapse Formation by Promoting Nogo-66 Receptor Ectodomain Shedding.	MMP24 MMP14 MMP16	8.48e-08	5	72	3	29196321
Pubmed	Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases.	MMP24 MMP14 MMP16	2.96e-07	7	72	3	12879005
Pubmed	Membrane-type matrix metalloproteinases: Their functions and regulations.	MMP24 MMP14 MMP16	2.96e-07	7	72	3	25794647
Pubmed	Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway.	STK4 PPP2CA PPP2CB	3.80e-06	15	72	3	38474134
Pubmed	[From gene to disease: copper-transporting P ATPases alteration].	ATP7A ATP7B	4.23e-06	2	72	2	19046832
Pubmed	Copper efflux transporters ATP7A and ATP7B: Novel biomarkers for platinum drug resistance and targets for therapy.	ATP7A ATP7B	4.23e-06	2	72	2	29394468
Pubmed	Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels.	ATP7A ATP7B	4.23e-06	2	72	2	8082762
Pubmed	Activation of SV40 DNA replication in vitro by cellular protein phosphatase 2A.	PPP2CA PPP2CB	4.23e-06	2	72	2	2555176
Pubmed	Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins.	ATP7A ATP7B	4.23e-06	2	72	2	19645496
Pubmed	Differential intracellular localisation of the Menkes and Wilson copper transporting ATPases in the third trimester human placenta.	ATP7A ATP7B	4.23e-06	2	72	2	21115196
Pubmed	Expression in mouse kidney of membrane copper transporters Atp7a and Atp7b.	ATP7A ATP7B	4.23e-06	2	72	2	12372948
Pubmed	Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells.	ATP7A ATP7B	4.23e-06	2	72	2	18565219
Pubmed	Copper transporting P-type ATPases and human disease.	ATP7A ATP7B	4.23e-06	2	72	2	12539960
Pubmed	The role of protein phosphatase 2A catalytic subunit Calpha in embryogenesis: evidence from sequence analysis and localization studies.	PPP2CA PPP2CB	4.23e-06	2	72	2	10543450
Pubmed	Mechanisms of charge transfer in human copper ATPases ATP7A and ATP7B.	ATP7A ATP7B	4.23e-06	2	72	2	28164426
Pubmed	Hormonal regulation of the Menkes and Wilson copper-transporting ATPases in human placental Jeg-3 cells.	ATP7A ATP7B	4.23e-06	2	72	2	17109627
Pubmed	Quantitative relationship between mutated amino-acid sequence of human copper-transporting ATPases and their related diseases.	ATP7A ATP7B	4.23e-06	2	72	2	18688737
Pubmed	Regulation of spindle formation by active mitogen-activated protein kinase and protein phosphatase 2A during mouse oocyte meiosis.	PPP2CA PPP2CB	4.23e-06	2	72	2	11751260
Pubmed	Biochemical basis of regulation of human copper-transporting ATPases.	ATP7A ATP7B	4.23e-06	2	72	2	17562324
Pubmed	Genes regulating copper metabolism.	ATP7A ATP7B	4.23e-06	2	72	2	9823011
Pubmed	Expression and localization of menkes and Wilson copper transporting ATPases in human placenta.	ATP7A ATP7B	4.23e-06	2	72	2	15135234
Pubmed	Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes.	ATP7A ATP7B	4.23e-06	2	72	2	17717039
Pubmed	Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters.	ATP7A ATP7B	4.23e-06	2	72	2	9215673
Pubmed	Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients.	ATP7A ATP7B	4.23e-06	2	72	2	20045993
Pubmed	In vivo modulation of polo-like kinases supports a key role for PLK2 in Ser129 α-synuclein phosphorylation in mouse brain.	PLK2 PLK3	4.23e-06	2	72	2	24128992
Pubmed	Copper-transporting ATPases ATP7A and ATP7B: cousins, not twins.	ATP7A ATP7B	4.23e-06	2	72	2	18000748
Pubmed	Regulation of the apico-basolateral trafficking polarity of the homologous copper-ATPases ATP7A and ATP7B.	ATP7A ATP7B	4.23e-06	2	72	2	38032054
Pubmed	Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities.	PPP2CA PPP2CB	4.23e-06	2	72	2	34902541
Pubmed	Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes.	PPP2CA PPP2CB	4.23e-06	2	72	2	2837763
Pubmed	Molecular features of copper binding proteins involved in copper homeostasis.	ATP7A ATP7B	4.23e-06	2	72	2	27896900
Pubmed	Structure and transcriptional regulation of protein phosphatase 2A catalytic subunit genes.	PPP2CA PPP2CB	4.23e-06	2	72	2	1846293
Pubmed	Investigation on PLK2 and PLK3 substrate recognition.	PLK2 PLK3	4.23e-06	2	72	2	22828320
Pubmed	Menkes disease: recent advances and new insights into copper metabolism.	ATP7A ATP7B	4.23e-06	2	72	2	8732640
Pubmed	Membrane-type MMPs enable extracellular matrix permissiveness and mesenchymal cell proliferation during embryogenesis.	MMP14 MMP16	4.23e-06	2	72	2	18022611
Pubmed	PP2A regulates kinetochore-microtubule attachment during meiosis I in oocyte.	PPP2CA PPP2CB	4.23e-06	2	72	2	27096707
Pubmed	Trafficking of the copper-ATPases, ATP7A and ATP7B: role in copper homeostasis.	ATP7A ATP7B	4.23e-06	2	72	2	17531189
Pubmed	Intracellular targeting of copper-transporting ATPase ATP7A in a normal and Atp7b-/- kidney.	ATP7A ATP7B	4.23e-06	2	72	2	17928409
Pubmed	Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A.	ATP7A ATP7B	4.23e-06	2	72	2	28271598
Pubmed	[Structure and function of ATP7A and ATP7B proteins--Cu-transporting ATPases].	ATP7A ATP7B	4.23e-06	2	72	2	21117320
Pubmed	Regional expression of protein phosphatase type 1 and 2A catalytic subunit isoforms in the human heart.	PPP2CA PPP2CB	4.23e-06	2	72	2	11113010
Pubmed	Matrix metalloproteinases in tumor invasion.	MMP24 MMP14 MMP16	4.67e-06	16	72	3	10949577
Pubmed	Adhesion induced expression of the serine/threonine kinase Fnk in human macrophages.	PLK2 PLK3	1.27e-05	3	72	2	11039900
Pubmed	Matrix metalloproteinase gene polymorphisms and bronchopulmonary dysplasia: identification of MMP16 as a new player in lung development.	MMP14 MMP16	1.27e-05	3	72	2	18784838
Pubmed	MT1-MMP as a downstream target of BCR-ABL/ABL interactor 1 signaling: polarized distribution and involvement in BCR-ABL-stimulated leukemic cell migration.	ABL1 MMP14	1.27e-05	3	72	2	17943163
Pubmed	The polo-like protein kinases Fnk and Snk associate with a Ca(2+)- and integrin-binding protein and are regulated dynamically with synaptic plasticity.	PLK2 PLK3	1.27e-05	3	72	2	10523297
Pubmed	The catalytic subunit of protein phosphatase 2A is carboxyl-methylated in vivo.	PPP2CA PPP2CB	1.27e-05	3	72	2	8206937
Pubmed	Copper-dependent interaction of glutaredoxin with the N termini of the copper-ATPases (ATP7A and ATP7B) defective in Menkes and Wilson diseases.	ATP7A ATP7B	1.27e-05	3	72	2	16884690
Pubmed	Intestinal expression of metal transporters in Wilson's disease.	ATP7A ATP7B	1.27e-05	3	72	2	23963605
Pubmed	Clusterin (apolipoprotein J), a molecular chaperone that facilitates degradation of the copper-ATPases ATP7A and ATP7B.	ATP7A ATP7B	1.27e-05	3	72	2	21242307
Pubmed	A cancer cell metalloprotease triad regulates the basement membrane transmigration program.	MMP14 MMP16	1.27e-05	3	72	2	16983145
Pubmed	Tyrosine phosphorylation of protein phosphatase 2A in response to growth stimulation and v-src transformation of fibroblasts.	PPP2CA PPP2CB	1.27e-05	3	72	2	7510677
Pubmed	Association between polymorphisms in CTR1, CTR2, ATP7A, and ATP7B and platinum resistance in epithelial ovarian cancer.	ATP7A ATP7B	1.27e-05	3	72	2	28737129
Pubmed	Assignment of the human genes for membrane-type-1, -2, and -3 matrix metalloproteinases (MMP14, MMP15, and MMP16) to 14q12.2, 16q12.2-q21, and 8q21, respectively, by in situ hybridization.	MMP14 MMP16	1.27e-05	3	72	2	9119382
Pubmed	ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal dopamine-β-hydroxylase.	ATP7A ATP7B	1.27e-05	3	72	2	30341172
Pubmed	Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification.	ATP7A ATP7B	1.27e-05	3	72	2	23751120
Pubmed	The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death.	STK4 ABL1	1.27e-05	3	72	2	21715626
Pubmed	The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum.	ATP7A ATP7B	1.27e-05	3	72	2	15634671
Pubmed	Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis.	ATP7A ATP7B	1.27e-05	3	72	2	10557326
Pubmed	Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.	ATP7A ATP7B	1.27e-05	3	72	2	20566629
Pubmed	Characterization of the interaction between the Wilson and Menkes disease proteins and the cytoplasmic copper chaperone, HAH1p.	ATP7A ATP7B	1.27e-05	3	72	2	10497213
Pubmed	CD26 expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesion.	VCAN MMP14	1.27e-05	3	72	2	24180670
Pubmed	Mutation of Tyr307 and Leu309 in the protein phosphatase 2A catalytic subunit favors association with the alpha 4 subunit which promotes dephosphorylation of elongation factor-2.	PPP2CA PPP2CB	1.27e-05	3	72	2	10441131
Pubmed	Protein phosphatase 2A dephosphorylates CaBP4 and regulates CaBP4 function.	PPP2CA PPP2CB	1.27e-05	3	72	2	23341017
Pubmed	Localization of the genes encoding the catalytic subunits of protein phosphatase 2A to human chromosome bands 5q23-->q31 and 8p12-->p11.2, respectively.	PPP2CA PPP2CB	1.27e-05	3	72	2	8383590
Pubmed	Overlapping binding sites in protein phosphatase 2A for association with regulatory A and alpha-4 (mTap42) subunits.	PPP2CA PPP2CB	1.27e-05	3	72	2	15252037
Pubmed	Functional interactions between matrix metalloproteinases and glycosaminoglycans.	MMP24 MMP14 MMP16	1.27e-05	22	72	3	23421805
Pubmed	Matrix metalloproteinases.	MMP24 MMP14 MMP16	1.27e-05	22	72	3	10419448
Pubmed	Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.	MMP24 MMP14 MMP16	1.67e-05	24	72	3	15734845
Pubmed	HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.	PPP2CA PPP2CB CCNB2	2.14e-05	26	72	3	11531413
Pubmed	Clusterin and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A and ATP7B.	ATP7A ATP7B	2.53e-05	4	72	2	22130675
Pubmed	GSK-3β is Dephosphorylated by PP2A in a Leu309 Methylation-Independent Manner.	PPP2CA PPA1	2.53e-05	4	72	2	26484916
Pubmed	Phosphorylation and microtubule association of the Opitz syndrome protein mid-1 is regulated by protein phosphatase 2A via binding to the regulatory subunit alpha 4.	PPP2CA PPP2CB	2.53e-05	4	72	2	11371618
Pubmed	Expression pattern of four membrane-type matrix metalloproteinases in the normal and diseased mouse mammary gland.	MMP14 MMP16	2.53e-05	4	72	2	15895410
Pubmed	The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation.	PPP2CA PPP2CB	2.53e-05	4	72	2	21454489
Pubmed	Genomic organization of the mottled gene, the mouse homologue of the human Menkes disease gene.	ATP7A ATP7B	2.53e-05	4	72	2	8921375
Pubmed	Dual role of LRRC8A-containing transporters on cisplatin resistance in human ovarian cancer cells.	ATP7A ATP7B	2.53e-05	4	72	2	27112899
Pubmed	The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic.	PPP2CA PPP2CB	2.53e-05	4	72	2	14633983
Pubmed	Generation of Ppp2Ca and Ppp2Cb conditional null alleles in mouse.	PPP2CA PPP2CB	2.53e-05	4	72	2	21998041
Pubmed	Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha.	PPP2CA PPP2CB	2.53e-05	4	72	2	9770493
Pubmed	Phosphatase activity toward abnormally phosphorylated tau: decrease in Alzheimer disease brain.	PPP2CA PPP2CB	2.53e-05	4	72	2	7616230
Pubmed	Identification of a domain of Axin that binds to the serine/threonine protein phosphatase 2A and a self-binding domain.	PPP2CA PPP2CB	2.53e-05	4	72	2	9920888
Pubmed	Prion fragment peptides are digested with membrane type matrix metalloproteinases and acquire enzyme resistance through Cu²⁺-binding.	MMP14 MMP16	2.53e-05	4	72	2	24970228
Pubmed	Identification and assessment of PLK1/2/3/4 in lung adenocarcinoma and lung squamous cell carcinoma: Evidence from methylation profile.	PLK2 PLK3	2.53e-05	4	72	2	34080290
Pubmed	Binding of the proline-rich segment of myelin basic protein to SH3 domains: spectroscopic, microarray, and modeling studies of ligand conformation and effects of posttranslational modifications.	PHEX ABL1 NEB	2.69e-05	28	72	3	18067320
Pubmed	Atp7a and Atp7b regulate copper homeostasis in developing male germ cells in mice.	ATP7A ATP7B	4.21e-05	5	72	2	28820536
Pubmed	Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.	PLK2 PLK3	4.21e-05	5	72	2	19597481
Pubmed	Regulation of phosphorylation of neuronal microtubule-associated proteins MAP1b and MAP2 by protein phosphatase-2A and -2B in rat brain.	PPP2CA PPP2CB	4.21e-05	5	72	2	10640627
Pubmed	His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia.	ABL1 NEB	4.21e-05	5	72	2	1682866
Pubmed	HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint.	PPP2CA PPP2CB	4.21e-05	5	72	2	9009195
Pubmed	Phosphorylation of synucleins by members of the Polo-like kinase family.	PLK2 PLK3	4.21e-05	5	72	2	19889641
Pubmed	Protein phosphatase 2A interacts with and directly dephosphorylates RelA.	PPP2CA PPP2CB	4.21e-05	5	72	2	11591705
Pubmed	Targeted disruption of the PME-1 gene causes loss of demethylated PP2A and perinatal lethality in mice.	PPP2CA PPP2CB	4.21e-05	5	72	2	18596935
Pubmed	HIV types, groups, subtypes and recombinant forms: errors in replication, selection pressure and quasispecies.	CD207 APOBEC3F	4.21e-05	5	72	2	22286874
Pubmed	Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.	MMP24 MMP14 MMP16	5.78e-05	36	72	3	20587546
Pubmed	Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation.	PPP2CA PPP2CB CDC27	6.28e-05	37	72	3	26811472
Pubmed	Distinct role of protein phosphatase 2A subunit Calpha in the regulation of E-cadherin and beta-catenin during development.	PPP2CA PPP2CB	6.31e-05	6	72	2	10781942
Pubmed	Endotoxin conditioning induces VCP/p97-mediated and inducible nitric-oxide synthase-dependent Tyr284 nitration in protein phosphatase 2A.	PPP2CA PPP2CB	6.31e-05	6	72	2	20100830
Pubmed	Global loss of leucine carboxyl methyltransferase-1 causes severe defects in fetal liver hematopoiesis.	PPP2CA PPP2CB	6.31e-05	6	72	2	29735529
Interaction	KISS1 interactions	MMP24 MMP14 MMP16	2.64e-05	17	70	3	int:KISS1
Interaction	MMP16 interactions	MMP24 MMP14 MMP16	3.15e-05	18	70	3	int:MMP16
Interaction	MMP24 interactions	MMP24 MMP14 MMP16	3.74e-05	19	70	3	int:MMP24
Cytoband	19q13.4	CACNG8 ZNF606 CNOT3	2.68e-04	79	72	3	19q13.4
Cytoband	4p15.2	LGI2 SEL1L3	8.93e-04	28	72	2	4p15.2
GeneFamily	ATPase copper transporting	ATP7A ATP7B	6.61e-06	2	47	2	1212
GeneFamily	Endogenous ligands\|Matrix metallopeptidases	MMP24 MMP14 MMP16	3.21e-05	24	47	3	891
GeneFamily	Protein phosphatase catalytic subunits\|EF-hand domain containing	PPP2CA PPP2CB	5.07e-04	13	47	2	693
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	PPP2CA PPP2CB	1.22e-03	20	47	2	1371
ToppCell	facs-Trachea-nan-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGB LRRC34 ATP7B PLK5 MORN3	9.01e-06	173	72	5	27ae126c720f20d1fe116abbcd358e4cff8baf6b
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGB LRRC34 ATP7B PLK5 MORN3	9.27e-06	174	72	5	f1510b0f7771936adf29ae3572feab55db31832b
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGB LRRC34 ATP7B PLK5 MORN3	9.27e-06	174	72	5	5d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCell	droplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGB LRRC34 AZGP1 PLK5 MORN3	1.35e-05	188	72	5	0eca3dc93724e23b71e687fc24fa9f1e89bdef6a
ToppCell	droplet-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGB LRRC34 AZGP1 PLK5 MORN3	1.35e-05	188	72	5	9ce3e1fffce87ad19812ecbf9b7f9935a975d676
ToppCell	droplet-Lung-18m-Epithelial-airway_epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGB LRRC34 AZGP1 PLK5 MORN3	1.38e-05	189	72	5	fe958fdf9963c2dfe270f67f0da36b3264d0017c
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLDC TENM1 NPAS3 MMP16 RYR2	1.73e-05	198	72	5	d1827e3707b929e3a3562989a0c11537d344e164
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PHEX VCAN MMP14 SDK1 RYR2	1.77e-05	199	72	5	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	erythropoietic-Polychromatic_Erythroblast\|erythropoietic / Lineage and Cell class	CCNB2 NCEH1 MINPP1 RRM1 CDC27	1.81e-05	200	72	5	27056f28328df2a51d5634a7927b7084241e3ca2
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate\|6m / Sample Type, Dataset, Time_group, and Cell type.	RAPSN LGI2 RBBP6 VCAN NEB	1.81e-05	200	72	5	7c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCell	COVID_vent\|World / Disease condition, Lineage, Cell class and subclass	IGLV3-10 IGHV3-33 VCAN SEL1L3 PPA1	1.81e-05	200	72	5	1d88e5cc4534073f27a7562e1c4b884bd67f09d9
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHIA PRIM1 EDC4 CD300E	6.61e-05	134	72	4	45c0cccca133ffc261ba45271d72b21f5402ec3c
ToppCell	E16.5-samps\|World / Age Group, Lineage, Cell class and subclass	CCNB2 PRIM1 VCAN RRM1	9.98e-05	149	72	4	e94d075f68c1c70c89fab50b1b765b5dda650d09
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK5 LETM2 ABCA5 TENM1	1.13e-04	154	72	4	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DOCK5 LETM2 ABCA5 TENM1	1.13e-04	154	72	4	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	mild_COVID-19_(asymptomatic)-B_intermediate\|World / disease group, cell group and cell class (v2)	IGLV3-10 PLK5 SEL1L3 GATM	1.31e-04	160	72	4	6722934e153b72039c3c4308557d0ef879a30638
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC25A32 PRIM1 RRM1 MMP16	1.34e-04	161	72	4	f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell	368C-Lymphocytic-Plasma_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGLV3-10 IGHV3-33 GLDC SEL1L3	1.38e-04	162	72	4	c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell	368C-Lymphocytic-Plasma_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	IGLV3-10 IGHV3-33 GLDC SEL1L3	1.38e-04	162	72	4	f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	1.41e-04	163	72	4	a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell	5'-Airway_Nasal_SMG-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	1.41e-04	163	72	4	454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	1.41e-04	163	72	4	d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	1.41e-04	163	72	4	f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell	5'-Airway_Nasal_SMG\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	1.41e-04	163	72	4	d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	1.41e-04	163	72	4	be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 PRIM1 NEB RRM1	1.58e-04	168	72	4	c09aa66fd1374ecc4b4d4b56600a6f04aafa5be9
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PHEX AZGP1 CNOT3 RYR2	1.58e-04	168	72	4	c66a61d3ec711796313a2c6d2dc39aedbfc20afd
ToppCell	368C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	PHEX AZGP1 CNOT3 RYR2	1.58e-04	168	72	4	83b4f817d95daa15ae60668e789f97d8a3b2e6dd
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ADGB PLK5 CD207 GATM	1.62e-04	169	72	4	9c9bb1b32fc6e22359424a262178906c3954415d
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GDAP1L1 VTN AZGP1 NEB	1.69e-04	171	72	4	fa5cc720bd0045d0307439be547b41d56def5b43
ToppCell	P07-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADGB TENM1 GATM NEB	1.73e-04	172	72	4	8d6a2a0d5f63b09a5a304a77e600a647f87e9de4
ToppCell	tumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th\|T/NK_cells / Location, Cell class and cell subclass	VCAN NEB CDC27 KDM6A	1.77e-04	173	72	4	42c911ed16fabdabef063830e8407192d8bde950
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RAPSN CCNB2 HGSNAT GATM	1.77e-04	173	72	4	12c6875f881cb0fbff09d753b53c1cce7a95527f
ToppCell	facs\|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LETM2 LGI2 MMP14 BIRC6	1.85e-04	175	72	4	53e96956019f984decc1c81376ebc88fbf3c4d40
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHEX PRIM1 VCAN PPA1	1.89e-04	176	72	4	d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LRP12 GATM NCEH1 RRM1	1.89e-04	176	72	4	450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD207 HGSNAT MMP14 CD300E	1.93e-04	177	72	4	43883b65b1e03043a24fc40c84c50bac81960c12
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGLV3-10 IGHV3-33 GLDC SEL1L3	1.93e-04	177	72	4	4c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IGLV3-10 IGHV3-33 GLDC SEL1L3	1.93e-04	177	72	4	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	droplet-Lung-LUNG-30m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD207 HGSNAT MMP14 CD300E	1.93e-04	177	72	4	9de6a82b7fb72d20361947f7ac95bb1fa73fc2ff
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC25A32 PRIM1 GATM RRM1	1.93e-04	177	72	4	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGLV3-10 IGHV3-33 GLDC SEL1L3	1.93e-04	177	72	4	d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGLV3-10 IGHV3-33 GLDC SEL1L3	1.93e-04	177	72	4	fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD207 HGSNAT MMP14 CD300E	1.98e-04	178	72	4	c85de851b39cb8ef7ea1866ab64c6a387788273a
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV3-10 IGHV3-33 GLDC SEL1L3	2.02e-04	179	72	4	837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PLK2 CD207 EDC4 PLK3	2.02e-04	179	72	4	42f3c040f504a91cc69292d39d22b5715c12526f
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PLK2 CD207 EDC4 PLK3	2.02e-04	179	72	4	063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCell	droplet-Lung-30m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_33\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD207 HGSNAT MMP14 CD300E	2.02e-04	179	72	4	13d80ae2e43a5daad0aeb5f47338efca2c58800a
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV3-10 IGHV3-33 GLDC SEL1L3	2.02e-04	179	72	4	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGLV3-10 IGHV3-33 GLDC SEL1L3	2.02e-04	179	72	4	b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PHEX NPAS3 SDK1 RYR2	2.06e-04	180	72	4	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RXFP2 TENM1 NPAS3 SDK1	2.06e-04	180	72	4	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 GATM NCEH1 RRM1	2.15e-04	182	72	4	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCNB2 TENM1 RRM1 MORN3	2.15e-04	182	72	4	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	2.15e-04	182	72	4	2f7d9c0bf7155ac376e63fc9d9542b5c3ab89f04
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	2.15e-04	182	72	4	9b556e44ed6aaa50ec572224f5751fb02ce63438
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 NEB SDK1 RYR2	2.24e-04	184	72	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLK2 AZGP1 GATM SLC4A11	2.24e-04	184	72	4	00db9eaaffe9c598222e14b2f9638cbcce1602d7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	VCAN KDM6A SDK1 RYR2	2.24e-04	184	72	4	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 NEB SDK1 RYR2	2.24e-04	184	72	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM1 NEB SDK1 RYR2	2.24e-04	184	72	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP12 CCNB2 NCEH1 RRM1	2.29e-04	185	72	4	57c1eb50a4456d20953e48d5dc3b0ea3d0d81b6d
ToppCell	343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LGI2 NPAS3 GATM MMP14	2.34e-04	186	72	4	9673367cb53bafb873a01ef6bda11d9f392ce648
ToppCell	droplet-Lung-nan-18m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC34 AZGP1 PLK5 MORN3	2.34e-04	186	72	4	740fd06bcd3b24e6ff2ecf8080f378afc3e95084
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LGI2 RPE65 SDK1 RYR2	2.34e-04	186	72	4	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLK2 VCAN MMP14 SDK1	2.34e-04	186	72	4	360c3e9e5c3a943e68e6939b4a47821bfc75b553
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP2CB CCNB2 GATM PPA1	2.34e-04	186	72	4	af038994a6c32261f426b0c40c39be4a9099fe43
ToppCell	droplet-Lung-nan-18m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC34 AZGP1 PLK5 MORN3	2.34e-04	186	72	4	5ab43a298d23238b34e898d11decf0ad81d1b14e
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DOCK5 STK4 CD207 GATM	2.38e-04	187	72	4	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	LGI2 GATM NEB MMP14	2.38e-04	187	72	4	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PHEX MMP14 SDK1 RYR2	2.48e-04	189	72	4	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PHEX VCAN NPAS3 RYR2	2.53e-04	190	72	4	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PHEX VCAN SDK1 RYR2	2.53e-04	190	72	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	droplet-Heart-nan-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VCAN MMP14 MMP16 RYR2	2.53e-04	190	72	4	96a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCell	ASK454-Immune-Macrophages\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	ATP7A VCAN CD300E	2.54e-04	76	72	3	f4fdc5cb2a561e58ea020dac48ee8647577f9713
ToppCell	5'-Adult-LargeIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGLV3-10 STK4 IGHV3-33 SEL1L3	2.58e-04	191	72	4	d1d30279ed4612b4f62c225d9eabf0b8a7a09d11
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PHEX VCAN SDK1 RYR2	2.58e-04	191	72	4	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	(3)_MNP-(3)_DC_activated\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	STK4 MMP24 VTN PPA1	2.58e-04	191	72	4	0353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCell	Dividing_Macrophages-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	VTN CCNB2 PRIM1 RRM1	2.58e-04	191	72	4	3e567ed6b5fefafa7f460e49d25d60bb52a0a6c8
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LGI2 VCAN MMP14 MMP16	2.58e-04	191	72	4	4b50fdd310701251e64e16cd2d07ce03dbfd3e3e
ToppCell	(3)_MNP-(3)_DC_2\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	STK4 CD207 GATM PPA1	2.58e-04	191	72	4	3ff163484af8c12ef4eef87246cf044257fd2547
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LGI2 VCAN MMP14 MMP16	2.58e-04	191	72	4	75d2197076a9dfc868e8baf95bd4c5e44f438e3e
ToppCell	control-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KLHDC2 ABCA5 MINPP1 APOBEC3F	2.58e-04	191	72	4	afebdc59a1f884ce3f2f5fe040e16b0e95e4e7c5
ToppCell	COPD-Myeloid-cDC1\|Myeloid / Disease state, Lineage and Cell class	STK4 ABL1 PPA1 SDK1	2.58e-04	191	72	4	3480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCell	IPF-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	PLK2 AZGP1 SEL1L3 PPA1	2.58e-04	191	72	4	267e1192aaec468c1a59eb24848b37e0e18cbc44
ToppCell	COPD-Myeloid-cDC2\|Myeloid / Disease state, Lineage and Cell class	STK4 CD207 HGSNAT PPA1	2.64e-04	192	72	4	984cdc2f1d93e164bc946d63f58dacb629f82eb7
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	VCAN ARL15 KDM6A SDK1	2.64e-04	192	72	4	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	droplet-Marrow-BM-1m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP2CA PRIM1 MINPP1 RRM1	2.64e-04	192	72	4	ced2fdbcb181ac250ff50cd4d5d886e568924203
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PHEX MMP14 SDK1 RYR2	2.64e-04	192	72	4	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	droplet-Marrow-BM-1m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP2CA PRIM1 MINPP1 RRM1	2.64e-04	192	72	4	19b8675ed8a99bd3d08ad043e4ec9f006426c22f
ToppCell	356C-Myeloid-Dendritic-cDC2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	STK4 CD207 GATM PPA1	2.64e-04	192	72	4	a7ccbea7c90c070d279d7ad3f2b5b7c0e3efd890
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PHEX MMP14 SDK1 RYR2	2.64e-04	192	72	4	ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CACNG8 VCAN PSMA6 MMP16	2.64e-04	192	72	4	1d0d6fb89a2b941b7caab2f1f07d6bd5433a11e7
ToppCell	Control-Myeloid-cDC2\|Myeloid / Disease state, Lineage and Cell class	STK4 CD207 SEL1L3 PPA1	2.69e-04	193	72	4	4cb938c346cc32ec122d11e6b9f25db20e0f7ff6
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	VCAN ARL15 KDM6A SDK1	2.69e-04	193	72	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PHEX VCAN SDK1 RYR2	2.74e-04	194	72	4	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	IPF-Myeloid-cDC2\|Myeloid / Disease state, Lineage and Cell class	STK4 CD207 HGSNAT PPA1	2.74e-04	194	72	4	accf4b7b09e2048f2e47a52201e0158684dda8fe
ToppCell	Bronchial_Brush-Immune-Dendritic_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	STK4 CD207 HGSNAT PPA1	2.74e-04	194	72	4	dbcc00940538efc0f89f074dbe822c50efa5ad8e
ToppCell	E16.5\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CCNB2 PRIM1 PPA1 RRM1	2.74e-04	194	72	4	8a48f596cf1ca43718b9db661305c150e459f8d4
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	LRP12 CCNB2 NCEH1 RRM1	2.80e-04	195	72	4	c1435e61e4f0cf457f26ae436936048932ceb0db
Disease	occipital horn syndrome (implicated_via_orthology)	ATP7A ATP7B	5.08e-06	2	67	2	DOID:0111272 (implicated_via_orthology)
Disease	muscle measurement	PLK2 NEB	3.04e-05	4	67	2	EFO_0004515
Disease	metal metabolism disorder (implicated_via_orthology)	ATP7A ATP7B	3.04e-05	4	67	2	DOID:896 (implicated_via_orthology)
Disease	Wilson disease (implicated_via_orthology)	ATP7A ATP7B	5.06e-05	5	67	2	DOID:893 (implicated_via_orthology)
Disease	Menkes disease (implicated_via_orthology)	ATP7A ATP7B	5.06e-05	5	67	2	DOID:1838 (implicated_via_orthology)
Disease	MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE	RAPSN NEB	7.57e-05	6	67	2	C1854678
Disease	inorganic pyrophosphatase measurement	VTN PPA1	7.57e-05	6	67	2	EFO_0008157
Disease	Dupuytren Contracture	PJA2 LRP12 MMP14 SDK1	1.09e-04	108	67	4	EFO_0004229
Disease	level of Phosphatidylinositol (16:0_18:2) in blood serum	RAPSN CNOT3	1.41e-04	8	67	2	OBA_2045153
Disease	spinal muscular atrophy (implicated_via_orthology)	ATP7A ATP7B	1.81e-04	9	67	2	DOID:12377 (implicated_via_orthology)
Disease	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	ABL1 KDM6A CNOT3	2.42e-04	53	67	3	C1961099
Disease	level of Phosphatidylinositol (18:1_18:1) in blood serum	RAPSN CNOT3	3.90e-04	13	67	2	OBA_2045159
Disease	diacylglycerol 38:4 measurement	RAPSN CNOT3	4.54e-04	14	67	2	EFO_0020066
Disease	breast carcinoma (is_marker_for)	ATP7B MMP14 PLK3	4.62e-04	66	67	3	DOID:3459 (is_marker_for)
Disease	mannan-binding lectin serine protease 1 measurement	VTN FCN2	5.23e-04	15	67	2	EFO_0008223
Disease	esophagus squamous cell carcinoma (is_marker_for)	AZGP1 MMP14 KDM6A	6.46e-04	74	67	3	DOID:3748 (is_marker_for)
Disease	laryngeal squamous cell carcinoma	RAPSN VCAN	6.76e-04	17	67	2	EFO_0006352
Disease	level of Phosphatidylinositol (18:0_18:1) in blood serum	RAPSN CNOT3	7.59e-04	18	67	2	OBA_2045155
Disease	diacylglycerol 38:3 measurement	RAPSN CNOT3	8.47e-04	19	67	2	EFO_0020065
Disease	gestational age, birth measurement	RAPSN NPAS3	1.04e-03	21	67	2	EFO_0005112, EFO_0006921
Disease	esophagus adenocarcinoma (is_implicated_in)	ABL1 MMP14	1.04e-03	21	67	2	DOID:4914 (is_implicated_in)
Disease	Colorectal Carcinoma	GDAP1L1 ATP7B ABCA5 FCN2 TENM1 KDM6A CD300E	1.06e-03	702	67	7	C0009402
Disease	pallidum volume	PJA2 BIRC6	1.47e-03	25	67	2	EFO_0006933
Disease	spontaneous preterm birth	RXFP2 NPAS3 SDK1	1.59e-03	101	67	3	EFO_0006917
Disease	triacylglycerol 56:5 measurement	DOCK5 RAPSN	1.59e-03	26	67	2	EFO_0010432
Disease	fear of minor pain measurement	DOCK5 TENM1	2.26e-03	31	67	2	EFO_0008340

Protein segments in the cluster

Peptide	Gene	Start	Entry
WIFLLQYYEKKYGGR	ABCA5	1221	Q8WWZ7
KYWSRYYQGSQGVIF	ARL15	91	Q9NXU5
GSVYWYFVLLNYVKD	BIRC6	1446	Q9NR09
YGWHKFQGQCYKYFA	VCAN	3171	P13611
FNSYGKYVVKLYWMG	ADGB	191	Q8N7X0
VQLLGGWYFYVQAYK	ATP7B	706	P35670
MYKGYNKYWCRGQYD	CD300E	41	Q496F6
YAYQGNVWVGYDNIK	CHIA	326	Q9BZP6
IWAGTCYYIYKFTKG	ARMCX4	16	Q5H9R4
QGTYIYFDYEKWGQR	CNOT3	721	O75175
FGGWYFYIQAYKALK	ATP7A	726	Q04656
DEVFTYFYKGNKYWK	MMP14	471	P50281
YGKGWSLKYRAMSQY	RAPSN	196	Q13702
QPVAKYDWEQKYYYG	EDC4	121	Q6P2E9
LGGMGYFAYWYLKKK	GDAP1L1	351	Q96MZ0
WGLYFFFYNAIKSYK	SLC25A32	96	Q9H2D1
TYFYKGRDYWKFDNQ	MMP24	536	Q9Y5R2
KYYYNGFYLLWIDAK	LETM2	131	Q2VYF4
NGLKKHYYWTSTYGE	LRRC34	431	Q8IZ02
QWLKYFYGTFNSPNY	LRP12	261	Q9Y561
CSGDALPKKYAYWYQ	IGLV3-10	41	A0A075B6K4
EKYWPFYQKQGGHYF	GATM	101	P50440
EKKGYTFDYAYDWVG	CSNK1G1	316	Q9HCP0
YWKNAAFLYGLGLVY	KDM6A	126	O15550
YVMVKYWVDYFKGNY	NCEH1	246	Q6PIU2
KWVDYSSKYGFGYQL	PLK5	206	Q496M5
KYGNANVWKYFTDLF	PPP2CB	136	P62714
KYGNANVWKYFTDLF	PPP2CA	136	P67775
EWYEKYYKGYAAGAQ	RBBP6	836	Q7Z6E9
YYRWLNYGGVIKNYF	PRIM1	26	P49642
MGYKDFKYCWENFVY	APOBEC3F	331	Q8IUX4
KKNHYSYGWSFYFGG	CACNG8	196	Q8WXS5
YEGWYRGYTLQNKSK	DOCK5	41	Q9H7D0
GQGKWNLKQQYYTGY	CCNB2	321	O95067
INWKSGKGYNYSYKV	FCN2	291	Q15485
GQYGEVYEGVWKKYS	ABL1	251	P00519
VANLFPYKGYIWNYG	PPA1	81	Q15181
WVYKNKLIFFGGYGY	KLHDC2	151	Q9Y2U9
NYGGGKYWYFKHASW	HGSNAT	286	Q68CP4
NLAGYIWYKGQMTYL	PSG4	61	Q00888
NGNIQGYKIYYWEAD	SDK1	1731	Q7Z5N4
LGVSEGSAQYKKWYY	RYR2	661	Q92736
NAWYGLGMIYYKQEK	CDC27	636	P30260
YAVNGDYYVGEWKDN	MORN3	31	Q6PF18
WYDGSNKYYADSVKG	IGHV3-33	71	P01772
LKNKYLDWAYRSGGY	UTP6	476	Q9NYH9
WKGFEFVYNYLYLAN	RPE65	331	Q16518
VKGTVKIFWKYYYGH	SLC4A11	491	Q8NBS3
VNGLGWYYHKFKKNY	SEL1L3	766	Q68CR1
STVYKWNSKGFYSYQ	LGI2	351	Q8N0V4
PFWNKDYFGNFYGKN	RXFP2	556	Q8WXD0
KAYNKASGWTVQYYY	TENM1	2236	Q9UKZ4
CVTKYYRWMQKNGGY	NPAS3	391	Q8IXF0
FYGYYDNKRTIGWMN	TMC1	256	Q8TDI8
SQGWKYFKGNFYYFS	CD207	196	Q9UJ71
YWNVGFLKYYELKQV	PIGV	311	Q9NUD9
YEAANWKYKYGYEIP	PSMA6	96	P60900
KWVDYSNKFGFGYQL	PLK3	466	Q9H4B4
NGFTYFYKGKEYWKF	MMP16	496	P51512
LNDLKQYWKRGYGYT	MINPP1	316	Q9UNW1
YGWKQGLKTGMYYLR	RRM1	726	P23921
KNGNLKWYYYYQSAN	ZHX1	716	Q9UKY1
QYSNYYWKKAGLNVK	PHEX	621	P78562
SKTLYGLYWYKQKYG	TRAV34	46	A0A0B4J273
GLYWYKQKYGEGLIF	TRAV34	51	A0A0B4J273
SGAFWKYYYDGKDYI	AZGP1	131	P25311
VKYYGSYFKNTDLWI	STK4	86	Q13043
KWVDYSNKYGFGYQL	PLK2	506	Q9NYY3
VYFFKGKQYWEYQFQ	VTN	271	P04004
FWNGCGDYYQLYDKD	PJA2	411	O43164
AYKYNEWEKVFGYDS	ZNF606	371	Q8WXB4
KNQIWRSYIGMGYYN	GLDC	126	P23378
NEYKQDYNEWYKGLG	NEB	2166	P20929