Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

HBS1L ABCA3 GBP7 ABCA12 BMS1 ABCB1 MDN1 ATP11B GBP4 DNAH8 GNL1 DNAH9 EFL1 DNAH3 ARL16 NSF ABCB5 WRN ABCC5 CCT4 EIF2S3B MSH2 GTPBP1 TRAP1 DNAH12 EIF2S3 RAB7B MACF1 DDX53 SEPTIN7 SNRNP200 ATP2B4 DNAH11

1.80e-1177521733GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

HBS1L ABCA3 GBP7 ABCA12 BMS1 ABCB1 MDN1 ATP11B GBP4 DNAH8 GNL1 DNAH9 EFL1 DNAH3 ARL16 NSF ABCB5 WRN ABCC5 CCT4 EIF2S3B MSH2 GTPBP1 TRAP1 DNAH12 EIF2S3 RAB7B MACF1 DDX53 SEPTIN7 SNRNP200 ATP2B4 DNAH11

1.44e-1083921733GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

HBS1L ABCA3 GBP7 ABCA12 BMS1 ABCB1 MDN1 ATP11B GBP4 DNAH8 GNL1 DNAH9 EFL1 DNAH3 ARL16 NSF ABCB5 WRN ABCC5 CCT4 EIF2S3B MSH2 GTPBP1 TRAP1 DNAH12 EIF2S3 RAB7B MACF1 DDX53 SEPTIN7 SNRNP200 ATP2B4 DNAH11

1.48e-1084021733GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

HBS1L ABCA3 GBP7 ABCA12 BMS1 ABCB1 MDN1 ATP11B GBP4 DNAH8 GNL1 DNAH9 EFL1 DNAH3 ARL16 NSF ABCB5 WRN ABCC5 CCT4 EIF2S3B MSH2 GTPBP1 TRAP1 DNAH12 EIF2S3 RAB7B MACF1 DDX53 SEPTIN7 SNRNP200 ATP2B4 DNAH11

1.48e-1084021733GO:0016818
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

4.67e-10182177GO:0008569
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.36e-0842174GO:0047743
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.36e-0842174GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.36e-0842174GO:0045703
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

1.58e-08282177GO:0051959
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA3 ABCA12 ABCB1 MDN1 ATP11B DNAH8 DNAH9 DNAH3 NSF ABCB5 WRN ABCC5 CCT4 MSH2 TRAP1 DNAH12 MACF1 DDX53 SNRNP200 ATP2B4 DNAH11

1.64e-0844121721GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

ABCA3 ABCA12 DNAH14 ABCB1 MDN1 ATP11B DNAH8 DNAH9 DNAH3 NSF ABCB5 WRN ABCC5 CCT4 MSH2 TRAP1 DNAH12 DNAH17 MYO1F MACF1 DDX53 SNRNP200 ATP2B4 DNAH11

6.48e-0861421724GO:0140657
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.73e-0852174GO:0047115
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.73e-0852174GO:0072555
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.73e-0852174GO:1902121
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.73e-0852174GO:0047787
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.73e-0852174GO:0047020
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.73e-0852174GO:0047006
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.73e-0852174GO:0047086
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

1.27e-07372177GO:0045505
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.00e-0762174GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.63e-0772174GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.18e-0782174GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.18e-0782174GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.18e-0782174GO:0035671
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCA3 ABCB1 ABCB5 ABCC5 SLC47A2 SLC22A5

1.60e-06342176GO:0042910
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.64e-0692174GO:0047044
GeneOntologyMolecularFunctionNADP+ binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.64e-0692174GO:0070401
GeneOntologyMolecularFunctionbile acid binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.71e-06102174GO:0032052
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.71e-06102174GO:0047045
GeneOntologyMolecularFunctiontransmembrane transporter activity

SCN11A ABCA3 ABCA12 AKR1C4 SLC7A11 RYR3 ABCB1 PTK2B KCNU1 CLCN4 ATP11B SLC44A5 SCN5A PKD1 SCN10A SLC38A11 ABCB5 SLC34A2 ABCC5 GRID1 TTYH3 SLC47A2 SLC7A9 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 NIPAL1 KCNIP4 ATP2B4

4.61e-06118021731GO:0022857
GeneOntologyMolecularFunctionGTP binding

HBS1L GBP7 GIMAP2 BMS1 GBP4 EIF2B2 GNL1 MOCS1 EFL1 ARL16 EIF2S3B GTPBP1 TGM2 EIF2S3 RAB7B SEPTIN7

7.63e-0639721716GO:0005525
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

1.09e-05702177GO:0003777
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.25e-05142174GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.25e-05142174GO:0001758
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCA3 ABCB1 ABCB5 ABCC5

1.69e-05152174GO:0008559
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA3 ABCA12 SLC7A11 ABCB1 CLCN4 SLC44A5 ABCB5 SLC34A2 ABCC5 SLC47A2 SLC7A9 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 ATP2B4

1.95e-0547721717GO:0022804
GeneOntologyMolecularFunctiontransporter activity

SCN11A ABCA3 ABCA12 AKR1C4 SLC7A11 RYR3 ABCB1 PTK2B KCNU1 CLCN4 ATP11B SLC44A5 SCN5A PKD1 SCN10A SLC38A11 ABCB5 SLC34A2 ABCC5 GRID1 TTYH3 SLC47A2 SLC7A9 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 NIPAL1 KCNIP4 ATP2B4

2.63e-05128921731GO:0005215
GeneOntologyMolecularFunctionguanyl nucleotide binding

HBS1L GBP7 GIMAP2 BMS1 GBP4 EIF2B2 GNL1 MOCS1 EFL1 ARL16 EIF2S3B GTPBP1 TGM2 EIF2S3 RAB7B SEPTIN7

2.63e-0543921716GO:0019001
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

HBS1L GBP7 GIMAP2 BMS1 GBP4 EIF2B2 GNL1 MOCS1 EFL1 ARL16 EIF2S3B GTPBP1 TGM2 EIF2S3 RAB7B SEPTIN7

2.63e-0543921716GO:0032561
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC7A11 ABCC5 SLC7A9 SLC22A4 SLC22A5

2.68e-05332175GO:0072349
GeneOntologyMolecularFunctionWnt receptor activity

TSPAN12 FZD1 FZD5 PKD1

2.89e-05172174GO:0042813
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 FASN AKR1C3

3.12e-05342175GO:0016628
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity

HS3ST4 HS3ST3B1 HS3ST3A1

4.29e-0572173GO:0008467
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 MYO1F DNAH11

4.49e-051182178GO:0003774
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.73e-05202174GO:0004303
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity

HS3ST3B1 HS3ST3A1

1.18e-0422172GO:0033872
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.22e-04242174GO:0004745
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.68e-04262174GO:0004022
GeneOntologyMolecularFunctionNADPH binding

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.68e-04262174GO:0070402
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 ALDH18A1 AKR1C3

1.69e-04482175GO:0016620
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5

1.87e-04492175GO:0140359
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.96e-04272174GO:0008106
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C3

1.96e-04112173GO:0030283
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ABCA3 ABCA12 ABCB1 ATP11B

2.26e-04282174GO:0140326
GeneOntologyMolecularFunctionsodium:phosphate symporter activity

SLC34A2 SLC20A1 SLC20A2

2.59e-04122173GO:0005436
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.98e-04302174GO:0018455
GeneOntologyMolecularFunctiontranslation factor activity, RNA binding

HBS1L EIF2B2 EFL1 EIF2S3B GTPBP1 EIF2S3

3.29e-04852176GO:0008135
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C4 AKR1C1 AKR1C2 ALDH18A1 AKR1C3

3.52e-04562175GO:0016903
GeneOntologyMolecularFunctioncadherin binding

FXYD5 ITGA6 PROM1 EPS15L1 FASN NEO1 KDR USO1 EIF2S3 MACF1 SEPTIN7 HDLBP

3.54e-0433921712GO:0045296
GeneOntologyMolecularFunctionGTPase activity

HBS1L GBP7 BMS1 GBP4 GNL1 EFL1 ARL16 EIF2S3B GTPBP1 EIF2S3 RAB7B SEPTIN7

3.73e-0434121712GO:0003924
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.84e-04322174GO:0004033
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC7A11 CLCN4 SLC44A5 SLC34A2 SLC47A2 SLC7A9 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5

4.14e-0429621711GO:0015291
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ABCA3 ABCB1 ATP11B

4.22e-04142173GO:0140333
GeneOntologyMolecularFunctionsteroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.34e-04332174GO:0033764
GeneOntologyMolecularFunctionheparan sulfate sulfotransferase activity

HS3ST4 HS3ST3B1 HS3ST3A1

5.23e-04152173GO:0034483
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C4 AKR1C1 AKR1C2 FASN AKR1C3

5.66e-04622175GO:0016627
GeneOntologyMolecularFunctionNADP binding

AKR1C4 ME1 AKR1C1 AKR1C2 AKR1C3

5.66e-04622175GO:0050661
GeneOntologyMolecularFunctionsteroid binding

TMEM199 AKR1C4 AKR1C1 AKR1C2 PGR PROM1 AKR1C3

6.36e-041332177GO:0005496
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

ABCB1 ABCB5 ABCC5

6.39e-04162173GO:0015562
GeneOntologyMolecularFunctionamino-acid betaine transmembrane transporter activity

SLC22A4 SLC22A5

6.95e-0442172GO:0015199
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

6.95e-0442172GO:0047718
GeneOntologyMolecularFunctionflippase activity

ABCA3 ABCB1 ATP11B

7.69e-04172173GO:0140327
GeneOntologyMolecularFunctionsteroid dehydrogenase activity

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.28e-04392174GO:0016229
GeneOntologyMolecularFunctioncell adhesion molecule binding

FXYD5 ITGA6 PROM1 EPS15L1 FASN NEO1 SYK KDR UTRN CNTN4 TNC USO1 EIF2S3 MACF1 SEPTIN7 HDLBP

8.90e-0459921716GO:0050839
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.12e-04402174GO:0016709
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

STAB1 PCSK9 LIPC

9.16e-04182173GO:0030169
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SCN11A RYR3 PTK2B KCNU1 CLCN4 ATP11B SCN5A PKD1 SCN10A SLC34A2 GRID1 TTYH3 SLC47A2 SLC10A2 SLC20A1 SLC20A2 NIPAL1 KCNIP4 ATP2B4

1.10e-0379321719GO:0015075
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5 ATP2B4

1.23e-031092176GO:0042626
GeneOntologyMolecularFunctiontranslation elongation factor activity

HBS1L EFL1 GTPBP1

1.26e-03202173GO:0003746
GeneOntologyMolecularFunctiontranslation regulator activity, nucleic acid binding

HBS1L EIF2B2 EFL1 EIF2S3B GTPBP1 EIF2S3

1.41e-031122176GO:0090079
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SCN11A RYR3 PTK2B KCNU1 CLCN4 SCN5A PKD1 SCN10A SLC34A2 ABCC5 TTYH3 SLC47A2 SLC10A2 SLC20A1 SLC20A2 NIPAL1 KCNIP4 ATP2B4

1.63e-0375821718GO:0015318
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC22A4 SLC22A5

1.71e-0362172GO:0015226
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity involved in cardiac muscle cell action potential

SCN5A SCN10A

1.71e-0362172GO:0086006
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SCN11A RYR3 KCNU1 SCN5A PKD1 SCN10A SLC34A2 SLC10A2 SLC20A1 SLC20A2 NIPAL1 KCNIP4 ATP2B4

1.80e-0346521713GO:0046873
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC34A2 SLC20A1 SLC20A2

2.16e-03242173GO:0005315
GeneOntologyMolecularFunctionsyntaxin-1 binding

STXBP2 NSF PRRT2

2.16e-03242173GO:0017075
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ABCA3 ABCA12 ABCB1 ATP11B

2.27e-03512174GO:0140303
GeneOntologyMolecularFunctionPDZ domain binding

SSTR2 FZD1 NSF SLC22A4 SLC22A5 ATP2B4

2.28e-031232176GO:0030165
GeneOntologyMolecularFunctionphosphatidylethanolamine flippase activity

ABCB1 ATP11B

2.38e-0372172GO:0090555
GeneOntologyMolecularFunctionapolipoprotein receptor binding

ABCA12 PCSK9

2.38e-0372172GO:0034190
GeneOntologyMolecularFunctionMutLalpha complex binding

WRN MSH2

2.38e-0372172GO:0032405
GeneOntologyMolecularFunctionsyntaxin binding

STXBP2 SYT3 NSF STXBP5L PRRT2

2.60e-03872175GO:0019905
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR1C4 ME1 AKR1C1 AKR1C2 FASN AKR1C3

2.67e-031272176GO:0016616
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SCN5A SCN10A SLC34A2 SLC10A2 SLC20A1 SLC20A2

2.71e-031712177GO:0015081
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A SCN5A SCN10A

2.74e-03262173GO:0005248
GeneOntologyMolecularFunctioncarbon-carbon lyase activity

ME1 MOCS1 ACMSD MVD

3.20e-03562174GO:0016830
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

EPHB3 TSPAN12 ERBB2 HLA-DPA1 HLA-DRA NPSR1 ADGRB2 SSTR2 PGR SORCS1 FZD1 PTK2B OR51B5 MS4A2 FZD5 PKD1 KDR OR51H1 TAPT1 OR9I1 GRID1 OR8U3 OR10J1 LEPR TGFBR1 OR51V1

3.35e-03135321726GO:0004888
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SCN11A RYR3 PTK2B KCNU1 SCN5A PKD1 SCN10A SLC34A2 SLC47A2 SLC10A2 SLC20A1 SLC20A2 NIPAL1 KCNIP4 ATP2B4

3.67e-0362721715GO:0022890
GeneOntologyMolecularFunctionSNARE binding

STXBP2 SYT11 SYT3 NSF STXBP5L PRRT2

3.75e-031362176GO:0000149
GeneOntologyMolecularFunctionubiquitin protein ligase binding

ERBB2 ABCB1 LAPTM5 PTK2B SYT11 FZD5 SCN5A SYK BAG5 TGFBR1

3.93e-0333721710GO:0031625
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C4 AKR1C1 AKR1C2 TNC AKR1C3

2.48e-0972165GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C4 AKR1C1 AKR1C2 TNC AKR1C3

2.48e-0972165GO:0071799
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.17e-0842164GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.17e-0842164GO:0006709
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.17e-0842164GO:0008208
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.17e-0842164GO:0071395
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.80e-0852164GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.80e-0852164GO:0120256
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.80e-0852164GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.80e-0852164GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.80e-0852164GO:0045827
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.80e-0852164GO:1900053
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.73e-0762164GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.73e-0762164GO:0016095
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.99e-0772164GO:1900052
GeneOntologyBiologicalProcesssodium ion transport

SCN11A FXYD5 SCN5A SCN10A SLC38A11 UTRN PCSK9 SLC34A2 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 ATP2B4

1.31e-0627521614GO:0006814
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.41e-0692164GO:0044597
GeneOntologyBiologicalProcessresponse to prostaglandin

SCN11A AKR1C4 AKR1C1 AKR1C2 TNC AKR1C3

1.84e-06362166GO:0034694
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.34e-06102164GO:0019747
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.34e-06102164GO:0044598
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.34e-06102164GO:0046137
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.34e-06102164GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.34e-06102164GO:0030647
GeneOntologyBiologicalProcesscellular response to prostaglandin stimulus

AKR1C4 AKR1C1 AKR1C2 TNC AKR1C3

3.47e-06232165GO:0071379
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.64e-06112164GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.64e-06112164GO:0016115
GeneOntologyBiologicalProcessxenobiotic transport

ABCA3 ABCB1 ABCB5 ABCC5 SLC47A2 SLC22A4 SLC22A5

4.69e-06642167GO:0042908
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.08e-05142164GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.08e-05142164GO:0008300
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.46e-05152164GO:0016102
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.93e-05162164GO:0061370
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.93e-05162164GO:0032351
GeneOntologyBiologicalProcessregulation of vitamin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.19e-05182164GO:0030656
GeneOntologyBiologicalProcessisoprenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3 MVD

3.48e-05362165GO:0008299
GeneOntologyBiologicalProcesspositive regulation of reactive oxygen species metabolic process

AKR1C4 AKR1C1 AKR1C2 PTK2B SYK ACE2 AKR1C3

4.17e-05892167GO:2000379
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.09e-05212164GO:0042447
GeneOntologyBiologicalProcessterpenoid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.09e-05212164GO:0016114
GeneOntologyBiologicalProcessregulation of retinoic acid receptor signaling pathway

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.09e-05212164GO:0048385
GeneOntologyBiologicalProcessketone catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.09e-05212164GO:0042182
GeneOntologyBiologicalProcessretinal metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.09e-05212164GO:0042574
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A FXYD5 SCN5A SCN10A UTRN PCSK9 SLC34A2 SLC20A1 SLC20A2 ATP2B4

7.13e-0520821610GO:0035725
GeneOntologyBiologicalProcesssecondary metabolic process

AKR1C4 SLC7A11 AKR1C1 AKR1C2 AKR1C3 ACMSD

7.21e-05672166GO:0019748
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.38e-05222164GO:0016137
GeneOntologyBiologicalProcessprogesterone metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.38e-05222164GO:0042448
GeneOntologyBiologicalProcessparturition

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.38e-05222164GO:0007567
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.38e-05222164GO:1902644
GeneOntologyBiologicalProcesscilium movement involved in cell motility

BBS1 DNAH14 DNAH8 DNAH9 DNAH3 DNAI3 DNAH12 DNAH17 ATP2B4 DNAH11

7.73e-0521021610GO:0060294
GeneOntologyBiologicalProcessprimary alcohol catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.86e-05232164GO:0034310
GeneOntologyBiologicalProcessmodified amino acid transport

SLC7A11 ABCC5 SLC7A9 SLC22A4 SLC22A5

9.37e-05442165GO:0072337
GeneOntologyBiologicalProcesscilium-dependent cell motility

BBS1 DNAH14 DNAH8 DNAH9 DNAH3 DNAI3 DNAH12 DNAH17 ATP2B4 DNAH11

9.39e-0521521610GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

BBS1 DNAH14 DNAH8 DNAH9 DNAH3 DNAI3 DNAH12 DNAH17 ATP2B4 DNAH11

9.39e-0521521610GO:0001539
GeneOntologyBiologicalProcessmonoatomic ion transport

SCN11A NPSR1 FXYD5 RYR3 ABCB1 PTK2B KCNU1 MS4A2 CLCN4 ATP11B SCN5A PKD1 SCN10A SLC38A11 UTRN PCSK9 NSF SLC34A2 ABCC5 GRID1 TTYH3 SLC47A2 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 NIPAL1 KCNIP4 ATP2B4

1.06e-04137421630GO:0006811
GeneOntologyBiologicalProcessmetal ion transport

SCN11A NPSR1 FXYD5 RYR3 PTK2B KCNU1 MS4A2 SCN5A PKD1 SCN10A SLC38A11 UTRN PCSK9 NSF SLC34A2 ABCC5 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 NIPAL1 KCNIP4 ATP2B4

1.37e-04100021624GO:0030001
GeneOntologyBiologicalProcessregulation of ketone biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.46e-04262164GO:0010566
GeneOntologyBiologicalProcesscarboxylic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 FASN SYK ALDH18A1 OAT LIPC MALRD1 AKR1C3 PNPLA8 ACMSD ATP2B4

1.68e-0437421613GO:0046394
GeneOntologyBiologicalProcessnegative regulation of small molecule metabolic process

AKR1C4 AKR1C1 AKR1C2 LEPR MALRD1 AKR1C3 ACMSD ATP2B4

1.79e-041492168GO:0062014
GeneOntologyBiologicalProcessorganic acid biosynthetic process

AKR1C4 AKR1C1 AKR1C2 FASN SYK ALDH18A1 OAT LIPC MALRD1 AKR1C3 PNPLA8 ACMSD ATP2B4

1.82e-0437721613GO:0016053
GeneOntologyBiologicalProcessglutamine family amino acid metabolic process

SLC7A11 GMPS ALDH18A1 MTERF1 OAT ATP2B4

1.94e-04802166GO:0009064
GeneOntologyBiologicalProcessnegative regulation of mRNA splicing, via spliceosome

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.97e-04282164GO:0048025
GeneOntologyBiologicalProcessxenobiotic export from cell

ABCA3 ABCB1 SLC47A2 SLC22A5

2.26e-04292164GO:0046618
GeneOntologyBiologicalProcesspolyprenol metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.26e-04292164GO:0016093
GeneOntologyBiologicalProcessnegative regulation of mRNA processing

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.26e-04292164GO:0050686
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SCN11A NPSR1 FXYD5 RYR3 ABCB1 PTK2B KCNU1 MS4A2 CLCN4 ATP11B SCN5A PKD1 SCN10A UTRN PCSK9 SLC34A2 ABCC5 GRID1 TTYH3 SLC47A2 SLC20A1 SLC20A2 NIPAL1 KCNIP4 ATP2B4

2.80e-04111521625GO:0034220
GeneOntologyBiologicalProcessprostaglandin metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3 PNPLA8

2.98e-04562165GO:0006693
GeneOntologyBiologicalProcesscarnitine metabolic process

BBOX1 SLC22A4 SLC22A5

3.00e-04132163GO:0009437
GeneOntologyBiologicalProcessresponse to calcium ion

AKR1C4 AKR1C1 AKR1C2 RYR3 PTK2B SCN5A SYT3 AKR1C3

3.03e-041612168GO:0051592
GeneOntologyBiologicalProcessprostanoid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3 PNPLA8

3.23e-04572165GO:0006692
GeneOntologyBiologicalProcesscellular response to calcium ion

AKR1C4 AKR1C1 AKR1C2 RYR3 SCN5A AKR1C3

3.26e-04882166GO:0071277
GeneOntologyBiologicalProcesspositive regulation of endothelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.34e-04322164GO:2000353
GeneOntologyBiologicalProcesstube development

EPHB3 TSPAN12 ERBB2 ABCA3 ABCA12 IFT172 DZIP1L ADGRB2 SLC7A11 PGR STAB1 FZD1 PHEX PTK2B PROM1 FZD5 PKD1 SYK KDR C5 HS3ST3B1 HS3ST3A1 TNC CNMD ATXN1L LEPR TGFBR1 TGM2 ATP2B4

3.45e-04140221629GO:0035295
GeneOntologyBiologicalProcessregulation of hormone metabolic process

AKR1C4 AKR1C1 AKR1C2 ARNT AKR1C3

3.51e-04582165GO:0032350
GeneOntologyBiologicalProcessanimal organ morphogenesis

TSPAN12 ABCA12 IFT172 BBS1 ITGA6 PGR FZD1 FANCD2 PHEX PROM1 PIM1 FZD5 SCN5A PKD1 SCN10A SYK KDR HS3ST3B1 HS3ST3A1 AGTPBP1 WHRN TMEM176B TNC TGFBR1 TGM2 PAX4 DNAH11

3.63e-04126921627GO:0009887
GeneOntologyBiologicalProcessnegative regulation of RNA splicing

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.77e-04332164GO:0033119
GeneOntologyBiologicalProcesscarboxylic acid transport

AKR1C4 SLC7A11 AKR1C1 ABCB1 SYK SLC38A11 DPYSL2 ABCC5 TTYH3 SLC7A9 ACE2 SLC10A2 PNPLA8

4.08e-0441021613GO:0046942
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.24e-04342164GO:0006706
GeneOntologyBiologicalProcessorganic acid transport

AKR1C4 SLC7A11 AKR1C1 ABCB1 SYK SLC38A11 DPYSL2 ABCC5 TTYH3 SLC7A9 ACE2 SLC10A2 PNPLA8

4.27e-0441221613GO:0015849
GeneOntologyBiologicalProcesscilium movement

BBS1 DNAH14 DNAH8 DNAH9 DNAH3 DNAI3 DNAH12 DNAH17 ATP2B4 DNAH11

4.48e-0426121610GO:0003341
GeneOntologyBiologicalProcessolefinic compound biosynthetic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.75e-04352164GO:0120255
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process

HS3ST4 HS3ST3B1 HS3ST3A1 LIPC

4.75e-04352164GO:0015012
GeneOntologyBiologicalProcessmonoatomic cation transport

SCN11A NPSR1 FXYD5 RYR3 PTK2B KCNU1 MS4A2 SCN5A PKD1 SCN10A SLC38A11 UTRN PCSK9 NSF SLC34A2 ABCC5 SLC47A2 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 NIPAL1 KCNIP4 ATP2B4

4.84e-04115721625GO:0006812
GeneOntologyBiologicalProcessretinoic acid receptor signaling pathway

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.53e-04382164GO:0048384
GeneOntologyBiologicalProcessglutamate metabolic process

SLC7A11 ALDH18A1 MTERF1 OAT

6.53e-04382164GO:0006536
GeneOntologyBiologicalProcessheparan sulfate proteoglycan metabolic process

HS3ST4 HS3ST3B1 HS3ST3A1

6.91e-04172163GO:0030201
GeneOntologyBiologicalProcessresponse to type II interferon

GBP7 HLA-DPA1 STXBP2 GBP4 PIM1 SLC22A5 RAB7B

7.24e-041412167GO:0034341
GeneOntologyBiologicalProcessregulation of cell adhesion

EPHB3 ERBB2 HLA-DPA1 ABCA12 HLA-DRA FXYD5 ITGA6 VIT LAPTM5 PTK2B PKD1 SYK KDR UTRN TBCD TNC CBFB TGM2 BRD7 MYO1F MACF1

7.67e-0492721621GO:0030155
GeneOntologyBiologicalProcessregulation of sodium ion transmembrane transport

FXYD5 SCN5A UTRN PCSK9 ATP2B4

7.84e-04692165GO:1902305
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.96e-04402164GO:0042573
GeneOntologyBiologicalProcessregulation of amino acid metabolic process

SLC7A11 ACMSD ATP2B4

8.23e-04182163GO:0006521
GeneOntologyBiologicalProcessamino-acid betaine metabolic process

BBOX1 SLC22A4 SLC22A5

8.23e-04182163GO:0006577
GeneOntologyBiologicalProcessregulation of reactive oxygen species metabolic process

AKR1C4 AKR1C1 AKR1C2 PTK2B SYK ACE2 TRAP1 AKR1C3

8.45e-041882168GO:2000377
GeneOntologyBiologicalProcessregulation of ketone metabolic process

AKR1C4 SLC7A11 AKR1C1 AKR1C2 MALRD1 AKR1C3 ACMSD ATP2B4

8.75e-041892168GO:0010565
GeneOntologyBiologicalProcesslipid transport

ABCA3 ABCA12 AKR1C4 AKR1C1 ABCB1 ATP11B SYK PDZD8 PCSK9 LBP LIPC SLC10A2 PNPLA8 HDLBP

9.41e-0450621614GO:0006869
GeneOntologyBiologicalProcesscellular response to fatty acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.59e-04422164GO:0071398
GeneOntologyBiologicalProcessregulated exocytosis

SCN11A ABCA12 STXBP2 MS4A2 SYT11 SYK SYT3 STXBP5L PRRT2 MYO1F

1.03e-0329121610GO:0045055
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SCN11A NPSR1 FXYD5 RYR3 PTK2B KCNU1 MS4A2 CLCN4 SCN5A PKD1 SCN10A UTRN PCSK9 SLC34A2 ABCC5 TTYH3 SLC47A2 SLC20A1 SLC20A2 NIPAL1 KCNIP4 ATP2B4

1.05e-03101721622GO:0098660
GeneOntologyBiologicalProcesscitrulline biosynthetic process

ALDH18A1 ATP2B4

1.07e-0352162GO:0019240
GeneOntologyBiologicalProcessregulation of endothelial cell apoptotic process

AKR1C4 AKR1C1 AKR1C2 KDR AKR1C3

1.08e-03742165GO:2000351
GeneOntologyBiologicalProcessdicarboxylic acid metabolic process

ME1 SLC7A11 ALDH18A1 MTERF1 OAT ACMSD

1.12e-031112166GO:0043648
GeneOntologyBiologicalProcessadhesion of symbiont to host

GBP7 GBP4 ACE2

1.13e-03202163GO:0044406
GeneOntologyBiologicalProcesslung alveolus development

ABCA12 SLC7A11 PGR KDR ATXN1L

1.14e-03752165GO:0048286
GeneOntologyCellularComponentdynein complex

DNAH14 DNAH8 DNAH9 DNAH3 DNAI3 DNAH12 DNAH17 DNAH11

8.48e-08542188GO:0030286
GeneOntologyCellularComponentaxonemal dynein complex

DNAH8 DNAH9 DNAH3 DNAI3 DNAH12 DNAH17

1.80e-07252186GO:0005858
GeneOntologyCellularComponentaxoneme

IFT172 DZIP1L BBS1 DNAH8 DNAH9 DNAH3 INPP5E DNAI3 DNAH12 DNAH17 SEPTIN7 DNAH11

1.92e-0620721812GO:0005930
GeneOntologyCellularComponentciliary plasm

IFT172 DZIP1L BBS1 DNAH8 DNAH9 DNAH3 INPP5E DNAI3 DNAH12 DNAH17 SEPTIN7 DNAH11

2.02e-0620821812GO:0097014
GeneOntologyCellularComponentapical plasma membrane

ERBB2 MPDZ ABCB1 PROM1 STXBP2 SLC34A2 ABCC5 SI SLC47A2 SLC7A9 TGFBR1 ACE2 SLC10A2 SLC20A2 SLC22A4 SLC22A5 SEPTIN7 CEACAM20

3.85e-0648721818GO:0016324
GeneOntologyCellularComponentapical part of cell

ERBB2 MPDZ SLC7A11 ABCB1 PROM1 STXBP2 SLC34A2 ABCC5 SI SLC47A2 SLC7A9 TGFBR1 ACE2 SLC10A2 SLC20A2 SLC22A4 SLC22A5 SEPTIN7 CEACAM20

1.54e-0559221819GO:0045177
GeneOntologyCellularComponentmotile cilium

PRAMEF10 IFT172 BBS1 DNAH14 KCNU1 PKD1 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 SEPTIN7 ATP2B4 DNAH11

2.33e-0535521814GO:0031514
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

IFT172 DZIP1L BBS1 DNAH8 DNAH9 AGTPBP1 DNAH3 INPP5E DNAI3 DNAH12 DNAH17 SEPTIN7 DNAH11

3.05e-0531721813GO:0032838
GeneOntologyCellularComponentactin-based cell projection

ERBB2 ITGA6 SLC7A11 PROM1 UTRN MPP1 WHRN SLC34A2 LIPC SLC10A2 MYO1F CEACAM20

3.77e-0527821812GO:0098858
GeneOntologyCellularComponent9+2 motile cilium

IFT172 DNAH14 KCNU1 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 SEPTIN7 ATP2B4 DNAH11

4.29e-0523821811GO:0097729
GeneOntologyCellularComponentmicrovillus

ERBB2 SLC7A11 PROM1 SLC34A2 LIPC SLC10A2 MYO1F CEACAM20

4.53e-051232188GO:0005902
GeneOntologyCellularComponentcilium

PRAMEF10 IFT172 DZIP1L BBS1 DNAH14 PROM1 KCNU1 CLCN4 PKD1 DNAH8 DNAH9 WHRN DNAH3 TAPT1 INPP5E CCT4 DNAI3 ACE2 DNAH12 DNAH17 SEPTIN7 ATP2B4 DNAH11

6.86e-0589821823GO:0005929
GeneOntologyCellularComponentcytoplasmic region

IFT172 DZIP1L BBS1 DNAH8 DNAH9 AGTPBP1 DNAH3 INPP5E DNAI3 DNAH12 DNAH17 SEPTIN7 DNAH11

1.11e-0436021813GO:0099568
GeneOntologyCellularComponentcluster of actin-based cell projections

SLC7A11 PROM1 MPP1 WHRN SLC34A2 SI SLC7A9 ACE2 SLC20A2 SLC22A5

1.23e-0422321810GO:0098862
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAI3 DNAH12

1.27e-04102183GO:0036156
GeneOntologyCellularComponentbrush border

SLC7A11 PROM1 SLC34A2 SI SLC7A9 ACE2 SLC20A2 SLC22A5

1.99e-041522188GO:0005903
GeneOntologyCellularComponentouter dynein arm

DNAH8 DNAH9 DNAH17

2.30e-04122183GO:0036157
GeneOntologyCellularComponentbrush border membrane

SLC7A11 SLC34A2 SLC7A9 ACE2 SLC20A2 SLC22A5

2.32e-04832186GO:0031526
GeneOntologyCellularComponentmicrotubule associated complex

DNAH14 DNAH8 DNAH9 DNAH3 DNAI3 DNAH12 DNAH17 DNAH11

2.95e-041612188GO:0005875
GeneOntologyCellularComponentcell projection membrane

ERBB2 BBS1 SLC7A11 PROM1 PKD1 UTRN SLC34A2 SLC7A9 ACE2 SLC20A2 SLC22A5 MACF1 CEACAM20

6.27e-0443121813GO:0031253
GeneOntologyCellularComponentlamellar body membrane

ABCA3 ABCA12

6.41e-0442182GO:0097232
GeneOntologyCellularComponentC-fiber

SCN11A SCN10A

6.41e-0442182GO:0044299
GeneOntologyCellularComponentmicrovillus membrane

SLC7A11 PROM1 SLC34A2 CEACAM20

6.43e-04382184GO:0031528
GeneOntologyCellularComponentinterstitial matrix

VIT COL14A1 TNC

6.83e-04172183GO:0005614
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN11A SCN5A SCN10A

6.83e-04172183GO:0001518
GeneOntologyCellularComponentnascent polypeptide-associated complex

NACA2 NACA4P

1.06e-0352182GO:0005854
GeneOntologyCellularComponentplasma membrane protein complex

SCN11A ERBB2 HLA-DPA1 HLA-DRA ITGA6 MPDZ PTK2B EPS15L1 NEO1 MS4A2 SCN5A SCN10A SYK C5 UTRN TGFBR1 KCNIP4 TRAV27

1.53e-0378521818GO:0098797
GeneOntologyCellularComponenteukaryotic translation initiation factor 2 complex

EIF2S3B EIF2S3

1.58e-0362182GO:0005850
GeneOntologyCellularComponenthost intracellular region

GBP7 GBP4

1.58e-0362182GO:0043656
GeneOntologyCellularComponenthost cell cytoplasm

GBP7 GBP4

1.58e-0362182GO:0030430
GeneOntologyCellularComponenthost cell part

GBP7 GBP4

1.58e-0362182GO:0033643
GeneOntologyCellularComponenthost intracellular part

GBP7 GBP4

1.58e-0362182GO:0033646
GeneOntologyCellularComponenthost cell cytoplasm part

GBP7 GBP4

1.58e-0362182GO:0033655
GeneOntologyCellularComponentsymbiont-containing vacuole

GBP7 GBP4

1.58e-0362182GO:0020003
GeneOntologyCellularComponentsymbiont-containing vacuole membrane

GBP7 GBP4

1.58e-0362182GO:0020005
GeneOntologyCellularComponentcoated vesicle membrane

NCALD HLA-DPA1 HLA-DRA TMEM199 SYT11 FZD5 AP1M2 USO1

1.94e-032152188GO:0030662
GeneOntologyCellularComponentdistal axon

SCN11A PGR PTK2B NEO1 SYT11 WHRN MAPK8IP1 DPYSL2 PRRT2 ARPC5 TANC1 SEPTIN7

2.14e-0343521812GO:0150034
GeneOntologyCellularComponentpostsynapse

RPL22 ERBB2 CTTNBP2 MPDZ PGR PTK2B NEO1 PIAS3 SYT11 EIF2B2 UTRN WHRN DPYSL2 SYT3 NSF GRID1 PRRT2 MACF1 TANC1 RPL35 SEPTIN7

2.31e-03101821821GO:0098794
GeneOntologyCellularComponentpresynapse

RPL22 SCN11A ERBB2 CTTNBP2 PGR PTK2B EPS15L1 STXBP2 CLCN4 PIAS3 SYT11 SCN10A WHRN DPYSL2 PRRT2 TANC1 RPL35 SEPTIN7 ATP2B4

2.43e-0388621819GO:0098793
GeneOntologyCellularComponentclathrin coat

NCALD EPS15L1 SCN10A AP1M2

2.77e-03562184GO:0030118
GeneOntologyCellularComponentmale pronucleus

TBP RIF1

2.91e-0382182GO:0001940
GeneOntologyCellularComponentsodium channel complex

SCN11A SCN5A SCN10A

3.35e-03292183GO:0034706
GeneOntologyCellularComponentjunctional membrane complex

RYR3 BAG5

3.71e-0392182GO:0030314
GeneOntologyCellularComponenttransport vesicle membrane

NCALD HLA-DPA1 ABCA12 HLA-DRA SYT11 SYT3 AP1M2 PRRT2 USO1

3.76e-032932189GO:0030658
GeneOntologyCellularComponentGolgi-associated vesicle membrane

NCALD TMEM199 PKD1 AP1M2

3.77e-03612184GO:0030660
GeneOntologyCellularComponentbasal plasma membrane

ERBB2 FXYD5 ITGA6 PKD1 ABCC5 LEPR TGFBR1 SLC22A4 SLC22A5 ATP2B4

4.16e-0335421810GO:0009925
MousePhenoparturition failure

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.19e-06101704MP:0012010
MousePhenohypermyelination

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.52e-06111704MP:0010050
MousePhenoincreased oligodendrocyte number

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.39e-05131704MP:0010160
MousePhenodecreased vocalization

CTTNBP2 AKR1C4 AKR1C1 AKR1C2 NSF AKR1C3

1.85e-05461706MP:0020351
MousePhenoincreased circulating progesterone level

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.60e-05151704MP:0005186
MousePhenolong stride length

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.60e-05151704MP:0010540
MousePhenolong gestation period

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.60e-05151704MP:0002293
MousePhenoincreased stereotypic behavior

AKR1C4 AKR1C1 AKR1C2 PDZD8 TNC AKR1C3

4.23e-05531706MP:0001409
MousePhenoabnormal gestational length

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.66e-05181704MP:0002292
MousePhenoabnormal diestrus

AKR1C4 AKR1C1 AKR1C2 LEPR AKR1C3

6.06e-05351705MP:0009010
MousePhenodysmyelination

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.79e-05201704MP:0013438
MousePhenoblood vessel congestion

TSPAN12 ABCA3 ABCA12 SCN5A BAG5 ACE2

1.35e-04651706MP:0000255
MousePhenovisceral vascular congestion

ABCA3 ABCA12 SCN5A BAG5 ACE2

1.48e-04421705MP:0010017
MousePhenoabnormal vocalization

CTTNBP2 AKR1C4 AKR1C1 AKR1C2 EPS15L1 UTP20 NSF SI SLC20A2 AKR1C3 MVD

1.53e-0423717011MP:0001529
MousePhenopulmonary vascular congestion

ABCA3 ABCA12 BAG5 ACE2

1.86e-04241704MP:0010018
MousePhenodecreased oligodendrocyte number

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.19e-04251704MP:0009808
Domain-

HBS1L ABCA3 GBP7 ABCA12 GIMAP2 BMS1 DNAH14 ABCB1 MDN1 GBP4 HS3ST4 HS3ST3B1 HS3ST3A1 DNAH8 GNL1 DNAH9 MPP1 EFL1 DNAH3 NWD1 ARL16 NSF ABCB5 WRN ABCC5 MSH2 GTPBP1 DNAH12 EIF2S3 MYO1F RAB7B DDX53 SEPTIN7 SNRNP200 DNAH11

8.31e-13746212353.40.50.300
DomainP-loop_NTPase

HBS1L ABCA3 GBP7 ABCA12 GIMAP2 BMS1 DNAH14 ABCB1 MDN1 GBP4 HS3ST4 HS3ST3B1 HS3ST3A1 DNAH8 GNL1 DNAH9 MPP1 EFL1 DNAH3 NWD1 ARL16 NSF ABCB5 WRN ABCC5 MSH2 GTPBP1 DNAH12 EIF2S3 MYO1F RAB7B DDX53 SEPTIN7 SNRNP200 DNAH11

3.06e-1184821235IPR027417
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

5.55e-09142126IPR024317
DomainATPase_dyneun-rel_AAA

MDN1 DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

5.55e-09142126IPR011704
DomainAAA_8

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

5.55e-09142126PF12780
DomainAAA_5

MDN1 DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

5.55e-09142126PF07728
DomainDHC_fam

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

9.16e-09152126IPR026983
DomainDynein_heavy

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

9.16e-09152126PF03028
DomainDynein_heavy_dom

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

9.16e-09152126IPR004273
DomainAAA

ABCA3 ABCA12 ABCB1 MDN1 DNAH8 DNAH9 DNAH3 NSF ABCB5 ABCC5 DNAH12 SNRNP200 DNAH11

1.02e-0814421213SM00382
DomainAAA+_ATPase

ABCA3 ABCA12 ABCB1 MDN1 DNAH8 DNAH9 DNAH3 NSF ABCB5 ABCC5 DNAH12 SNRNP200 DNAH11

1.02e-0814421213IPR003593
DomainDynein_HC_stalk

DNAH14 DNAH8 DNAH9 DNAH3 DNAH11

3.31e-07142125IPR024743
DomainDynein_heavy_dom-2

DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

3.31e-07142125IPR013602
DomainDHC_N2

DNAH8 DNAH9 DNAH3 DNAH12 DNAH11

3.31e-07142125PF08393
DomainMT

DNAH14 DNAH8 DNAH9 DNAH3 DNAH11

3.31e-07142125PF12777
DomainTF_GTP-bd_dom

HBS1L BMS1 EFL1 GTPBP1 EIF2S3

1.84e-06192125IPR000795
DomainALDOKETO_REDUCTASE_1

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.21e-06102124PS00798
DomainALDOKETO_REDUCTASE_2

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.21e-06102124PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.21e-06102124PS00063
DomainAldo/ket_reductase_CS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.21e-06102124IPR018170
DomainAldo/keto_reductase

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.21e-06102124IPR020471
Domain-

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.64e-051621243.20.20.100
DomainNADP_OxRdtase_dom

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.42e-05172124IPR023210
DomainAldo_ket_red

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.42e-05172124PF00248
DomainAldo/ket_red/Kv-b

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.42e-05172124IPR001395
DomainEFTu-like_2

HBS1L EFL1 GTPBP1 EIF2S3

4.36e-05182124IPR004161
DomainGTP_EFTU_D2

HBS1L EFL1 GTPBP1 EIF2S3

4.36e-05182124PF03144
DomainG_TR_2

HBS1L EFL1 GTPBP1 EIF2S3

4.36e-05182124PS51722
DomainDHC_N1

DNAH8 DNAH9 DNAH11

7.74e-0582123PF08385
DomainDynein_heavy_dom-1

DNAH8 DNAH9 DNAH11

7.74e-0582123IPR013594
DomainABC_transporter_CS

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5

1.09e-04422125IPR017871
DomainPhos_transporter

SLC20A1 SLC20A2

1.28e-0422122IPR001204
DomainPHO4

SLC20A1 SLC20A2

1.28e-0422122PF01384
DomainNa_channel_asu

SCN11A SCN5A SCN10A

1.63e-04102123IPR001696
DomainNa_trans_assoc

SCN11A SCN5A SCN10A

1.63e-04102123IPR010526
DomainNa_trans_assoc

SCN11A SCN5A SCN10A

1.63e-04102123PF06512
DomainTransl_elong_EF1A/Init_IF2_C

HBS1L GTPBP1 EIF2S3

1.63e-04102123IPR009001
DomainABC_tran

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5

2.07e-04482125PF00005
DomainABC_TRANSPORTER_2

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5

2.07e-04482125PS50893
DomainABC_TRANSPORTER_1

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5

2.28e-04492125PS00211
DomainTransl_B-barrel

HBS1L EFL1 GTPBP1 EIF2S3

2.31e-04272124IPR009000
DomainABC_transporter-like

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5

2.51e-04502125IPR003439
DomainRecoverin

NCALD HPCAL1 KCNIP4

3.79e-04132123IPR028846
DomainKH_1

TDRKH PCBP3 DDX53 HDLBP

8.80e-04382124PF00013
Domain-

TDRKH PCBP3 DDX53 HDLBP

9.72e-043921243.30.1370.10
DomainKH

TDRKH PCBP3 DDX53 HDLBP

1.07e-03402124SM00322
DomainKH_dom

TDRKH PCBP3 DDX53 HDLBP

1.07e-03402124IPR004087
DomainC1-set_C

HLA-DPA1 HLA-DRA

1.25e-0352122PF16196
DomainMHC_II_alpha

HLA-DPA1 HLA-DRA

1.25e-0352122SM00920
DomainC1-set_C

HLA-DPA1 HLA-DRA

1.25e-0352122IPR032431
DomainKH_TYPE_1

TDRKH PCBP3 DDX53 HDLBP

1.29e-03422124PS50084
DomainKH_dom_type_1

TDRKH PCBP3 DDX53 HDLBP

1.54e-03442124IPR004088
DomainARM-type_fold

CAND1 IFT172 RYR3 URB1 UTP20 AGTPBP1 TBCD API5 WDFY4 RIF1 USO1

1.76e-0333921211IPR016024
DomainMethyltransf_12

HNMT FASN

1.87e-0362122IPR013217
DomainMHC_II_alpha

HLA-DPA1 HLA-DRA

1.87e-0362122PF00993
DomainMethyltransf_12

HNMT FASN

1.87e-0362122PF08242
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

7.49e-07271736M47755
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA3 CAND1 ABCA12 SLC7A11 RYR3 ABCB1 CLCN4 ATP11B SLC44A5 PCSK9 ABCB5 SLC34A2 ABCC5 EIF2S3B TTYH3 SLC7A9 LIPC SLC20A1 SLC20A2 EIF2S3 SLC22A4 SLC22A5 NIPAL1 ATP2B4 HDLBP

8.73e-0768117325MM14985
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.63e-0691734M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.63e-0691734M47817
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ABCA3 CAND1 ABCA12 SLC7A11 RYR3 ABCB1 CLCN4 ATP11B SLC44A5 PCSK9 ABCB5 SLC34A2 ABCC5 TTYH3 SLC47A2 SLC7A9 LIPC SLC20A1 SLC20A2 EIF2S3 SLC22A4 SLC22A5 NIPAL1 ATP2B4 HDLBP

3.53e-0673617325M27287
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.76e-06111734M47812
PathwayREACTOME_PREDNISONE_ADME

AKR1C4 AKR1C1 AKR1C2 ABCB1 AKR1C3

7.39e-06231735MM16639
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

1.31e-05431736M47669
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.44e-05131734MM14747
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.44e-05131734M17842
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

1.72e-05451736M47670
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC34A2 SLC20A1 SLC20A2

1.78e-0551733M27345
PathwayREACTOME_SODIUM_COUPLED_PHOSPHATE_COTRANSPORTERS

SLC34A2 SLC20A1 SLC20A2

1.78e-0551733MM15085
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-05141734M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-05141734M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-05141734M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.99e-05141734MM14748
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.69e-05151734MM14870
PathwayREACTOME_RECYCLING_OF_EIF2_GDP

EIF2B2 EIF2S3B EIF2S3

1.45e-0491733MM15418
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.62e-04231734MM14741
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.62e-04231734M1926
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C4 AKR1C1 AKR1C2 SLC10A2 AKR1C3

1.94e-04441735M499
PathwayKEGG_ABC_TRANSPORTERS

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5

1.94e-04441735M11911
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCA3 ABCA12 ABCB1 ABCB5 ABCC5 EIF2S3B EIF2S3

2.14e-04991737MM14986
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C4 AKR1C1 AKR1C2 SLC10A2 AKR1C3

2.16e-04451735MM14751
PathwayBIOCARTA_VEGF_PATHWAY

EIF2B2 KDR ARNT EIF2S3

3.08e-04271734M12975
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.56e-04281734MM15188
PathwayWP_POLYCYSTIC_KIDNEY_DISEASE_PATHWAY

ERBB2 SSTR2 FZD1 FZD5 PKD1 KDR

6.15e-04851736M48315
PathwayREACTOME_DRUG_ADME

AKR1C4 AKR1C1 AKR1C2 ABCB1 GMPS ABCC5 AKR1C3

6.57e-041191737MM15692
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.79e-04331734MM14737
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

6.79e-04331734M5967
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C4 AKR1C1 AKR1C2 PGR AKR1C3

2.01e-107220522529366
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C4 AKR1C1 AKR1C2 LEPR AKR1C3

2.01e-107220534843575
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

CAND1 STAB1 FANCD2 GMPS FASN MDN1 FYTTD1 NSF CCT4 MSH2 API5 GTPBP1 RIF1 TRAP1 USO1 BRD7 MACF1 SEPTIN7 SNRNP200 HDLBP

1.15e-095822202020467437
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220410393440
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220431479646
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220410702227
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220417442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220428329705
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220416511129
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220415222881
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220410526179
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220421521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-09422048274401
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220410803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220434590152
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220410500239
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220419487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220414967952
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220415193432
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220416191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220415577209
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220417034817
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220429764944
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220417888864
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220419237748
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220428259989
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-09422047789999
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220420124700
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220416508162
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220417629694
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220416018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220417272929
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.56e-094220418667791
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL22 HBS1L CAND1 BMS1 FANCD2 FASN URB1 MDN1 WDR75 PIM1 ALDH18A1 UTP20 CLUH NSF OAT CCT4 MSH2 API5 GTPBP1 RIF1 TRAP1 USO1 EIF2S3 H1-0 SLTM PNPLA8 MPHOSPH8 RPL35 SEPTIN7 SNRNP200 HDLBP

2.18e-0914252203130948266
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

RPL22 HBS1L CAND1 ME1 BIRC6 FANCD2 GMPS EPS15L1 FASN PAPOLA EIF2B2 GNL1 CLUH TBCD EFL1 DPYSL2 BAG5 CCT4 MSH2 API5 ARPC5 TGM2 TRAP1 GTF2F2 EIF2S3 MACF1 RPL35 SEPTIN7 SNRNP200 MVD HDLBP

3.56e-0914552203122863883
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

EPHB3 ERBB2 TMEM199 ITGA6 FANCD2 NEO1 MDN1 HPCAL1 C5 DPY19L2 TAPT1 NSF BAG5 OAT TTYH3 SLC47A2 TGFBR1 RIF1 GTF2F2 USO1 SLC20A1 EIF2S3 SLC22A5 MACF1 SEPTIN7 ATP2B4

4.43e-0910612202633845483
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-09522047737980
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-095220438788959
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-095220418003893
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-095220421851338
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-095220416984997
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-095220417872381
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-095220417064890
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.75e-095220410672042
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BMS1 BIRC6 GMPS FASN URB1 MDN1 WDR75 ALDH18A1 UTP20 UTRN CLUH DPYSL2 OAT MSH2 RBM28 RIF1 SLTM MACF1 SNRNP200 HDLBP

8.04e-096532202022586326
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPL22 CAND1 CTTNBP2 PTK2B EPS15L1 FASN UTRN AGTPBP1 MAPK8IP1 DPYSL2 SYT3 NSF MTERF1 TNC OAT CCT4 EIF2S3B GTPBP1 ARPC5 USO1 EIF2S3 H1-0 MACF1 TANC1 RPL35 SEPTIN7 SNRNP200 ATP2B4 DNAH11 HDLBP

9.43e-0914312203037142655
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

RPL22 CAND1 ME1 AKR1C1 AKR1C2 FASN MDN1 ALDH18A1 UTRN AP1M2 CCT4 TGM2 TRAP1 EIF2S3 H1-0 SLTM AKR1C3 MACF1 RPL35 SNRNP200 MVD HDLBP

1.14e-088072202230575818
Pubmed

The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism.

AKR1C4 AKR1C1 AKR1C2 MALRD1 AKR1C3

1.20e-0813220511682476
Pubmed

Genetic determinants modulate susceptibility to pregnancy-associated tumourigenesis in a recombinant line of Min mice.

AKR1C4 AKR1C1 AKR1C2 CABLES1 AKR1C3

1.20e-0813220517062636
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH8 DNAH3 DNAH12 DNAH17 DNAH11

1.85e-081422059373155
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-086220419273550
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-086220415471942
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-086220426748576
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-086220417122075
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-086220429107092
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-086220415860270
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.31e-086220417255200
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

HBS1L PRAMEF10 GBP7 DZIP1L AKR1C4 AKR1C1 AKR1C2 URB1 POLR3D GBP4 WDR75 PAPOLA UTRN FYTTD1 INPP5E RALGPS2 RBM28 ATXN1L WDFY4 ARPC5 TGFBR1 SLC20A1 SLTM AKR1C3 MACF1

2.93e-0810842202511544199
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.37e-087220433127481
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.37e-087220412562828
Pubmed

Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk.

AKR1C1 AKR1C2 PGR AKR1C3

5.37e-087220419846565
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH8 DNAH3 DNAH12 DNAH11

5.37e-08722049256245
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.37e-087220426160177
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH8 DNAH9 DNAH17 DNAH11

5.37e-087220431178125
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.37e-087220416337335
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

ERBB2 SSTR2 PGR ABCB1 KDR TNC WRN MSH2 LEPR TGFBR1 ARNT SLC10A2 EXO1 AKR1C3

6.33e-083512201420453000
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-078220420837989
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-078220433584538
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-07822049224647
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RPL22 HBS1L CAND1 BMS1 BIRC6 GMPS FASN URB1 MDN1 WDR75 ALDH18A1 UTP20 PRR14L UTRN DPYSL2 CCT4 MSH2 RBM28 TGM2 RIF1 H1-0 SLTM MACF1 TANC1 RPL35 SNRNP200 HDLBP

1.49e-0713532202729467282
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RPL22 CAND1 ABCB1 FASN URB1 MDN1 STXBP2 WDR75 UTP20 UTRN NSF CCT4 MSH2 RBM28 RIF1 TRAP1 SLC20A1 H1-0 SLTM MACF1 RPL35 SNRNP200 HDLBP

1.74e-0710242202324711643
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RPL22 CAND1 BMS1 ITGA6 GMPS EPS15L1 FASN NAA25 ALDH18A1 GNL1 UTRN CLUH TBCD DPYSL2 NSF CCT4 TTYH3 GTPBP1 TGM2 USO1 SLC20A1 H1-0 SLTM RPL35 SEPTIN7 MVD HDLBP

1.83e-0713672202732687490
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.91e-079220433348080
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C1 AKR1C2 AKR1C3

2.50e-073220319320734
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C1 AKR1C2 AKR1C3

2.50e-073220321232532
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C1 AKR1C2 AKR1C3

2.50e-073220331780644
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C1 AKR1C2 AKR1C3

2.50e-073220313678667
Pubmed

Distribution of 3 alpha-hydroxysteroid dehydrogenase in rat brain and molecular cloning of multiple cDNAs encoding structurally related proteins in humans.

AKR1C4 AKR1C1 AKR1C3

2.50e-07322037626489
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.18e-0710220436313771
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RPL22 BMS1 FASN URB1 MDN1 WDR75 ALDH18A1 PDZD8 UTP20 FYTTD1 CCT4 MSH2 RBM28 RIF1 TRAP1 TRMT2A EIF2S3 SLTM MPHOSPH8 ISG20L2 RPL35 SNRNP200

3.85e-079892202236424410
Pubmed

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

RPL22 CAND1 MDN1 UTRN BAG5 CCT4 EIF2S3B API5 ARPC5 RIF1 EIF2S3 SLTM MACF1 RPL35 SEPTIN7 SNRNP200

3.92e-075382201628524877
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RPL22 CAND1 BMS1 BIRC6 URB1 MDN1 UTP20 AGTPBP1 FYTTD1 WRN MSH2 RBM28 GTPBP1 RIF1 EIF2S3 EXO1 MACF1 ISG20L2 SNRNP200

4.35e-077592201935915203
Pubmed

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.

ABCA3 AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.64e-0725220526098214
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

AKR1C4 AKR1C1 AKR1C2 LIPC SLC10A2 AKR1C3

5.17e-0747220611208732
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

HBS1L SCN11A CAND1 HLA-DRA HNMT ABCB1 PROM1 FASN STXBP2 PKD1 SCN10A C5 BBOX1 UTRN ZG16B GRID1 TTYH3 LBP ARPC5 ACE2 TGM2 SLC22A5

6.03e-0710162202219056867
Pubmed

Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.41e-0712220421256921
Pubmed

Timing of adrenal regression controlled by synergistic interaction between Sf1 SUMOylation and Dax1.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.41e-0712220428893949
Pubmed

A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-β1.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.41e-0712220425774556
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CAND1 IFT172 GMPS FASN MDN1 WDR75 NSF BAG5 CCT4 MSH2 API5 RIF1 TRAP1 USO1 EIF2S3 SEPTIN7 SNRNP200

7.72e-076382201733239621
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

GMPS FASN WDR75 FYTTD1 CCT4 RBM28 CBFB RIF1 USO1 BRD7 H1-0 SLTM ISG20L2

7.93e-073702201322922362
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

ERBB2 AKR1C4 PGR ABCB1 PIM1 WRN MSH2 LEPR TGFBR1 ARNT LIPC EXO1 AKR1C3

8.94e-073742201319625176
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

HBS1L CAND1 BMS1 MPDZ URB1 MDN1 WDR75 ALDH18A1 UTP20 UTRN TBP TDRKH FYTTD1 NSF WRN CCT4 API5 ARPC5 RIF1 GTF2F2 EIF2S3 BRD7 MACF1 MPHOSPH8 ISG20L2 TANC1 HDLBP

1.06e-0614972202731527615
Pubmed

Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20α-hydroxysteroid dehydrogenase in the mouse lung.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-0613220424580729
Pubmed

A link between lung androgen metabolism and the emergence of mature epithelial type II cells.

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.07e-0613220415117747
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

ERBB2 AKR1C4 PGR ABCB1 PIM1 WRN MSH2 LEPR TGFBR1 ARNT LIPC EXO1 AKR1C3

1.10e-063812201318676680
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RPL22 HBS1L CAND1 BMS1 GMPS FASN MDN1 STXBP2 WDR75 ALDH18A1 MPP1 NSF WRN OAT CCT4 MSH2 RBM28 GTPBP1 TGM2 TRAP1 TAF3 EIF2S3 H1-0 RPL35 SNRNP200

1.12e-0613182202530463901
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

ERBB2 AKR1C4 PGR ABCB1 PIM1 WRN MSH2 LEPR TGFBR1 ARNT LIPC EXO1 AKR1C3

1.13e-063822201319170196
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

BMS1 DGKH BIRC6 DNAH14 CABLES1 GMPS URB1 MDN1 PKD1 ALDH18A1 UTP20 UTRN DNAH3 DPYSL2 RBM28 ATXN1L EBLN1 SNRNP200

1.23e-067362201829676528
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RPL22 CAND1 MPDZ ME1 GMPS FASN MDN1 STXBP2 DPYSL2 PCBP3 NSF BAG5 CCT4 API5 ARPC5 TRAP1 USO1 EIF2S3 MACF1 RPL35 SEPTIN7 SNRNP200 HDLBP

1.26e-0611492202335446349
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

CAND1 GMPS TBCD DPYSL2 PCBP3 NSF MTERF1 CCT4 API5 GTPBP1 TRAP1 TRMT2A USO1 H1-0 SEPTIN7 SNRNP200 HDLBP

1.36e-066652201730457570
InteractionAKR1C4 interactions

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.76e-0782104int:AKR1C4
InteractionAKR1C1 interactions

AKR1C4 AKR1C1 AKR1C2 ACE2 AKR1C3

1.60e-06202105int:AKR1C1
InteractionGGCT interactions

FANCD2 GMPS STXBP2 TDRKH MTERF1 MSH2 ACE2

1.10e-05732107int:GGCT
InteractionEED interactions

RPL22 CAND1 BIRC6 FANCD2 GMPS PTK2B EPS15L1 FASN URB1 NAA25 STXBP2 ALDH18A1 UTP20 GNL1 CLUH TBCD FYTTD1 NSF CCT4 MSH2 API5 RBM28 ARPC5 RIF1 USO1 EIF2S3 H1-0 SLTM MACF1 ISG20L2 TANC1 SNRNP200 HDLBP

1.66e-05144521033int:EED
Cytoband10p15-p14

AKR1C1 AKR1C2 AKR1C3

2.15e-066220310p15-p14
Cytoband4p15.32

PROM1 TAPT1 KCNIP4

5.81e-051622034p15.32
CytobandXp22.2-p22.1

PHEX EIF2S3

2.26e-0452202Xp22.2-p22.1
CytobandEnsembl 112 genes in cytogenetic band chr7q31

TSPAN12 CTTNBP2 PPP1R3A PNPLA8 RNF133

5.96e-041402205chr7q31
GeneFamilyDyneins, axonemal

DNAH14 DNAH8 DNAH9 DNAH3 DNAH12 DNAH17 DNAH11

4.47e-11171517536
GeneFamilyAldo-keto reductases

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.94e-06151514399
GeneFamilySodium voltage-gated channel alpha subunits

SCN11A SCN5A SCN10A

4.62e-05915131203
GeneFamilyExonucleases

WRN EXO1 ISG20L2

2.95e-04161513544
GeneFamilySolute carriers

SLC7A11 SLC44A5 SLC38A11 SLC34A2 SLC47A2 SLC7A9 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5

4.92e-0439515111752
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C4 AKR1C1 AKR1C2 EIF2S3 AKR1C3

2.17e-07172185MM826
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_C_DN

AKR1C4 SLC7A11 AKR1C1 AKR1C2 AKR1C3

1.76e-06252185MM480
CoexpressionSERVITJA_LIVER_HNF1A_TARGETS_UP

AKR1C4 ME1 AKR1C1 AKR1C2 ABCB1 LEPR SLC20A1 SLC22A5 AKR1C3

4.86e-061502189MM936
CoexpressionHOFFMANN_PRE_BI_TO_LARGE_PRE_BII_LYMPHOCYTE_DN

GBP7 FXYD5 AKR1C4 AKR1C1 AKR1C2 MDN1 AKR1C3

7.12e-06852187MM802
CoexpressionBYSTROEM_CORRELATED_WITH_IL5_DN

CAND1 PAPOLA PIM1 SYK WRN ARNT

1.06e-05602186M1401
CoexpressionGSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_UP

ITGA6 GBP4 TDRKH RALGPS2 SI CBFB TGFBR1 NIPAL1 TANC1

1.47e-051722189M2945
CoexpressionRAY_TUMORIGENESIS_BY_ERBB2_CDC25A_UP

ABCA3 AKR1C4 AKR1C1 AKR1C2 PTK2B ATP11B HS3ST3B1 HS3ST3A1 ZG16B AKR1C3

1.62e-0521921810MM1237
CoexpressionBUSSLINGER_DUODENAL_IMMUNE_CELLS

RPL22 HLA-DPA1 CEP85L GIMAP2 FXYD5 ABCB1 LAPTM5 PTK2B MS4A2 PIM1 UTRN CCT4 CBFB ARPC5 TGFBR1 MYO1F MACF1 RPL35 SEPTIN7 SNRNP200 ATP2B4

2.65e-0591121821M40038
CoexpressionBYSTROEM_CORRELATED_WITH_IL5_DN

CAND1 PAPOLA PIM1 SYK WRN ARNT

3.86e-05752186MM605
CoexpressionGSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_UP

HNMT AKR1C1 AKR1C2 PGR EIF2B2 MAPK8IP1 TNC RIF1 AKR1C3

4.12e-051962189M10014
CoexpressionGSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN

ITGA6 NAA25 POLR3D MDN1 PIM1 ALDH18A1 UTP20 TRAP1 ATP2B4

4.28e-051972189M7458
CoexpressionGSE45365_CD8A_DC_VS_CD11B_DC_UP

HNMT AKR1C1 PGR FZD1 PAPOLA MTERF1 BAG5 RIF1 SEPTIN7

4.28e-051972189M9997
CoexpressionLIN_TUMOR_ESCAPE_FROM_IMMUNE_ATTACK

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.34e-05242184MM766
CoexpressionIBRAHIM_NRF2_UP

HBS1L ME1 SLC7A11 AKR1C1 AKR1C2 ABCB1 ATP11B PAPOLA FYTTD1 CBFB USO1 BRD7 SLTM AKR1C3 PNPLA8

4.41e-0553321815M42510
CoexpressionGSE6259_BCELL_VS_CD4_TCELL_DN

HBS1L HLA-DPA1 PROM1 EIF2B2 ALDH18A1 FYTTD1 CBFB SLC7A9 USO1

4.46e-051982189M6733
CoexpressionDESCARTES_ORGANOGENESIS_HEPATOCYTES

AKR1C4 GCKR AKR1C1 AKR1C2 C5 BBOX1 CLUH PCSK9 LBP SLC7A9 LIPC AKR1C3 NIPAL1 MVD HDLBP

4.60e-0553521815MM3635
CoexpressionGSE34156_TLR1_TLR2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP

TSPAN12 SLC7A11 PGR STXBP2 ATP11B TTYH3 TGM2 TMEM132E CEACAM20

4.82e-052002189M8693
CoexpressionGSE31082_DP_VS_CD8_SP_THYMOCYTE_DN

PTK2B NAA25 WDR75 ALDH18A1 NSF AP1M2 CCT4 RPL35 DNAH11

4.82e-052002189M5068
CoexpressionGSE39864_WT_VS_GATA3_KO_TREG_UP

ZNF777 GBP7 RYR3 GBP4 PIM1 KDR SLC7A9 ARNT EIF2S3

4.82e-052002189M9064
CoexpressionGSE20366_TREG_VS_NAIVE_CD4_TCELL_UP

HBS1L GBP7 ITGA6 ATP11B GBP4 PIM1 MPP1 ARL16 TGFBR1

4.82e-052002189M4347
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

HLA-DPA1 CEP85L GIMAP2 FXYD5 BIRC6 MYSM1 ABCB1 LAPTM5 PTK2B MS4A2 ATP11B PAPOLA PIM1 UTRN TBCD FYTTD1 CCT4 CBFB ARPC5 TGFBR1 RIF1 SLC20A1 MYO1F MACF1 MPHOSPH8 SEPTIN7 SNRNP200 ATP2B4

4.93e-05149221828M40023
CoexpressionSHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM3

ITGA6 AKR1C4 AKR1C1 AKR1C2 PROM1 AKR1C3

5.18e-05792186MM535
CoexpressionMURARO_PANCREAS_DUCTAL_CELL

HLA-DPA1 HLA-DRA ITGA6 HNMT AKR1C1 ABCB1 LAPTM5 STAB1 PROM1 ATP11B HPCAL1 PIM1 FZD5 SYK UTRN SLC34A2 TTYH3 ARPC5 TGM2 SLC20A1 EIF2S3 AKR1C3 MACF1 TANC1 ATP2B4

6.54e-05127621825M39173
CoexpressionTHUM_SYSTOLIC_HEART_FAILURE_UP

TSPAN12 HLA-DPA1 GIMAP2 HLA-DRA HNMT AKR1C1 LAPTM5 PAPOLA UTRN LEPR ACE2 TGM2 EIF2S3

7.00e-0543021813M3654
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

PTK2B PIAS3 KDR UTRN TNC TGFBR1 TGM2 HDLBP

8.57e-051682188M1124
CoexpressionTRAVAGLINI_LUNG_MUCOUS_CELL

ANKRD36C AKR1C1 AKR1C2 PROM1 KDR ZG16B TGM2

8.69e-051252187M41656
CoexpressionTABULA_MURIS_SENIS_SUBCUTANEOUS_ADIPOSE_TISSUE_EPITHELIAL_CELL_AGEING

AKR1C4 AKR1C1 AKR1C2 ABCB1 LAPTM5 COL14A1 DPYSL2 ABCC5 EIF2S3B ATXN1L ARPC5 ARNT EIF2S3 SLTM AKR1C3

8.98e-0556821815MM3824
CoexpressionKANG_IMMORTALIZED_BY_TERT_UP

SCN11A STXBP2 HPCAL1 TNC LEPR ACE2

9.49e-05882186M5360
CoexpressionPUJANA_ATM_PCC_NETWORK

RPL22 HLA-DPA1 HLA-DRA BMS1 SLC7A11 LAPTM5 URB1 POLR3D MS4A2 ATP11B PAPOLA SYK TBP MTERF1 INPP5E CCT4 MSH2 CBFB ARPC5 TGFBR1 RIF1 GTF2F2 ARNT EIF2S3 ISG20L2 PAX4

1.03e-04139421826M9585
CoexpressionCHEN_METABOLIC_SYNDROM_NETWORK

HBS1L SCN11A FXYD5 SSTR2 LAPTM5 STAB1 PTK2B STXBP2 HPCAL1 FZD5 SYK ALDH18A1 COL14A1 C5 MTERF1 TNC CNMD ABCC5 CBFB WDFY4 ARPC5 LIPC MYO1F RAB7B TANC1

1.06e-04131621825MM1052
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_SCP2_QTL_TRANS

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.08e-04302184MM853
CoexpressionCHEN_METABOLIC_SYNDROM_NETWORK

HBS1L SCN11A FXYD5 SSTR2 LAPTM5 STAB1 PTK2B STXBP2 HPCAL1 FZD5 SYK ALDH18A1 COL14A1 C5 TNC CNMD ABCC5 CBFB WDFY4 ARPC5 LIPC MYO1F RAB7B TANC1

1.14e-04124221824M1920
CoexpressionBYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS

TSPAN12 PRAMEF10 TMEM199 ITGA6 AKR1C4 AKR1C1 AKR1C2 PGR PROM1 STXBP2 SYK MPP1 FYTTD1 SYT3 INPP5E LBP CBFB MYO1F AKR1C3

1.33e-0487121819MM1005
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

EPHB3 ERBB2 STAB1 FZD1 PHEX FZD5 CNMD

1.41e-041352187M5825
CoexpressionMCBRYAN_PUBERTAL_TGFB1_TARGETS_UP

PTK2B PIAS3 KDR UTRN TNC TGFBR1 TGM2 HDLBP

1.49e-041822188MM993
CoexpressionBROWN_MYELOID_CELL_DEVELOPMENT_DN

HLA-DRA AKR1C4 AKR1C1 AKR1C2 MSH2 RIF1 AKR1C3

1.61e-041382187MM1151
CoexpressionFAN_EMBRYONIC_CTX_BRAIN_MYELOID

HLA-DPA1 HLA-DRA FXYD5 STXBP2 UTRN TMEM176B MYO1F

1.69e-041392187M39044
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

CAND1 PRAMEF10 FZD1 PAPOLA PIM1 FZD5 UTRN FYTTD1 TNC RBM28 TGFBR1 ARNT ISG20L2 HDLBP

1.97e-0454321814MM997
CoexpressionSCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN

CTTNBP2 ADGRB2 DGKH RYR3 CABLES1 HS3ST4 EIF2S3B TTYH3 LBP TMEM132E EIF2S3 RAB7B

2.05e-0441621812MM1002
CoexpressionGSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP

MPDZ PHEX FZD5 NTMT2 CNMD SLC10A2

2.14e-041022186M6681
CoexpressionYAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_6

AKR1C4 ME1 AKR1C1 AKR1C2 ABCB1 AKR1C3

2.14e-041022186MM872
CoexpressionDESCARTES_ORGANOGENESIS_INTERMEDIATE_MESODERM

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.23e-04362184MM3660
CoexpressionNADLER_HYPERGLYCEMIA_AT_OBESITY

AKR1C4 AKR1C1 AKR1C2 CCT4 AKR1C3

2.25e-04662185MM631
CoexpressionBMI1_DN_MEL18_DN.V1_DN

PROM1 COL14A1 TMEM176B NSF CNMD API5 LEPR

2.38e-041472187M2775
CoexpressionWANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_UP

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.48e-04372184MM630
CoexpressionGSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP

PLCXD2 ITGA6 PIM1 UTRN AGTPBP1 ATXN1L MYO1F PNPLA8

2.56e-041972188M4167
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN

IFT172 ABCB1 LAPTM5 CLCN4 GBP4 SLC38A11 HS3ST3B1 TAPT1

2.65e-041982188M9234
CoexpressionGSE360_DC_VS_MAC_L_MAJOR_DN

MPDZ MDN1 SCN5A TBP WRN SLC10A2 EIF2S3 MPHOSPH8

2.74e-041992188M5182
CoexpressionGSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN

ERBB2 PTK2B STXBP2 HPCAL1 UTRN TBCD BAG5 MYO1F

2.74e-041992188M5257
CoexpressionGSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN

ABCB1 LAPTM5 FANCD2 CLCN4 GBP4 SLC38A11 UTRN TAF3

2.74e-041992188M9236
CoexpressionHUANG_FOXA2_TARGETS_DN

TNC LEPR TGM2 ATP2B4

2.75e-04382184M16701
CoexpressionGOLDRATH_IMMUNE_MEMORY

AKR1C4 AKR1C1 AKR1C2 ABCB1 AKR1C3

2.77e-04692185MM621
CoexpressionLE_EGR2_TARGETS_DN

MPDZ ME1 ABCB1 UTRN MAPK8IP1 MVD

2.78e-041072186M15148
CoexpressionGSE9650_NAIVE_VS_EFF_CD8_TCELL_UP

AKR1C4 FASN MDN1 HPCAL1 PKD1 MPP1 RALGPS2 ABCC5

2.83e-042002188M5819
CoexpressionGSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_DN

GBP7 FXYD5 ITGA6 GBP4 PIM1 TMEM176B OAT LIPC

2.83e-042002188M8552
CoexpressionGSE17580_TREG_VS_TEFF_UP

HBS1L SCN11A GBP7 MDN1 PIM1 CNMD TGM2 H1-0

2.83e-042002188M3670
CoexpressionGSE30083_SP1_VS_SP4_THYMOCYTE_DN

GBP7 ITGA6 VIT AKR1C2 ATP11B C5 HS3ST3B1 DNAH8

2.83e-042002188M5030
CoexpressionGSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP

GBP7 HLA-DRA BMS1 GBP4 UTP20 UTRN ABCC5 USO1

2.83e-042002188M6558
CoexpressionGSE17721_12H_VS_24H_POLYIC_BMDC_DN

SYK UTRN CLUH OAT CCT4 TGM2 TRAP1 HDLBP

2.83e-042002188M4102
CoexpressionGSE7764_NKCELL_VS_SPLENOCYTE_UP

ABCB1 STXBP2 SYT11 PIM1 FZD5 CNMD MON1B NIPAL1

2.83e-042002188M5720
CoexpressionGSE7852_TREG_VS_TCONV_FAT_DN

BMS1 GMPS ATP11B HPCAL1 HS3ST3B1 TTYH3 SLC20A1 MYO1F

2.83e-042002188M5735
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

CTTNBP2 ITGA6 PROM1 NEO1 WDR75 PDZD8 PRR14L RIF1 SLC20A2 BRD7 MPHOSPH8 SNRNP200

3.01e-0443421812M15150
CoexpressionYAGI_AML_WITH_T_8_21_TRANSLOCATION

NCALD HLA-DPA1 HLA-DRA LAPTM5 MS4A2 FZD5 UTP20 DPYSL2 TGFBR1 AKR1C3 MACF1

3.05e-0437221811M19261
CoexpressionZAK_PBMC_MRKAD5_HIV_1_GAG_POL_NEF_AGE_20_50YO_1DY_DN

RPL22 NCALD ITGA6 ANKRD36C ABCB1 NEO1 MDN1 ALDH18A1 HS3ST3B1 AGTPBP1 RALGPS2 ABCC5 MSH2 EIF2S3 AKR1C3 MACF1 RPL35 SNRNP200 ATP2B4 TRAV27

3.24e-04101221820M40864
CoexpressionGOZGIT_ESR1_TARGETS_DN

HLA-DPA1 ABCA12 PLCXD2 ITGA6 MPDZ AKR1C1 PGR EPS15L1 ATP11B PIAS3 KDR UTRN ZG16B LEPR TGM2 AKR1C3 MACF1

3.33e-0478621817M10961
CoexpressionDESCARTES_FETAL_LIVER_HEPATOBLASTS

PLCXD2 TMEM199 AKR1C2 KCNU1 C5 SLC38A11 BBOX1 PCSK9 LBP ACE2 LIPC AKR1C3 ACMSD

3.38e-0450521813M40234
CoexpressionINGRAM_SHH_TARGETS_UP

ABCA3 PRAMEF10 AKR1C4 AKR1C1 AKR1C2 OAT AKR1C3

3.42e-041562187MM550
CoexpressionMANNE_COVID19_NONICU_VS_HEALTHY_DONOR_PLATELETS_DN

HLA-DRA PHEX KDR UTRN WDFY4 LEPR DNAH12 SEPTIN7

3.57e-042072188M38977
CoexpressionMANNE_COVID19_ICU_VS_HEALTHY_DONOR_PLATELETS_DN

HLA-DRA CABLES1 PHEX KDR UTRN LEPR DNAH12

3.83e-041592187M38979
CoexpressionBREDEMEYER_RAG_SIGNALING_NOT_VIA_ATM_UP

AKR1C4 AKR1C1 AKR1C2 SLC20A1 AKR1C3

3.84e-04742185MM769
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_A

AKR1C4 AKR1C1 AKR1C2 STXBP5L TRAP1 AKR1C3 ACMSD SEPTIN7

3.93e-042102188MM958
CoexpressionGRESHOCK_CANCER_COPY_NUMBER_UP

RPL22 ERBB2 FANCD2 GMPS PIM1 SYK WRN MSH2 CBFB ARNT

3.99e-0432321810M9150
CoexpressionZHANG_BREAST_CANCER_PROGENITORS_UP

CTTNBP2 ITGA6 PROM1 NEO1 WDR75 PDZD8 PRR14L RIF1 SLC20A2 BRD7 MPHOSPH8 SNRNP200

4.01e-0444821812MM1044
CoexpressionHOOI_ST7_TARGETS_DN

EPHB3 PHEX NAA25 KDR C5 AKR1C3

4.09e-041152186M14801
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

CAND1 FZD1 PAPOLA PIM1 FZD5 UTRN FYTTD1 TNC RBM28 TGFBR1 ARNT ISG20L2 HDLBP

4.37e-0451921813M3395
CoexpressionE2F3_UP.V1_DN

URB1 PCSK9 STXBP5L GRID1 TGM2 RIF1 MACF1

4.45e-041632187M2704
CoexpressionLE_EGR2_TARGETS_DN

MPDZ ME1 ABCB1 UTRN MAPK8IP1 MVD

4.49e-041172186MM1139
CoexpressionIVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR

RPL22 CAND1 GBP7 GMPS CLUH TDRKH FYTTD1 CCT4 LBP RBM28 CBFB WDFY4

4.87e-0445821812M1606
ToppCellBronchial_Biopsy-Immune-Mast_cells|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ABCA3 CTTNBP2 ABCB1 LAPTM5 STAB1 MS4A2 SYT11 SLC38A11 MPP1 DPYSL2 EIF2S3B

1.00e-0917221911c477008444d2d71071177807870d7455e90c2fad
ToppCell3'-Adult-SmallIntestine-Epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ME1 ABCB1 C5 SLC34A2 SI OAT SLC7A9 ACE2 MALRD1 SLC10A2

2.78e-0818421910ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ME1 ABCB1 C5 SI OAT SLC7A9 ACE2 MALRD1 SLC10A2 TMEM132E

3.08e-0818621910bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCell3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ME1 ABCB1 C5 SI OAT SLC7A9 ACE2 MALRD1 SLC10A2 TMEM132E

3.24e-08187219109042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

TSPAN12 NCALD SSTR2 SLC38A11 MOCS1 CNTN4 GRID1 PRRT2 SEPTIN7 DNAH11

3.58e-08189219109c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PHEX COL14A1 HS3ST3A1 CNTN4 PCBP3 TNC RALGPS2 GRID1 DNAI3 SPIDR

3.77e-081902191045df8fee00f8949937863159d7aa042e72748d9b
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CTTNBP2 HLA-DRA ME1 STAB1 FZD1 SYT11 TMEM176B ABCC5 TTYH3 RPL35

4.58e-081942191011ff53a748160570d2908ea9eb9779c038e5b676
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D231|Adult / Lineage, Cell type, age group and donor

HLA-DRA ME1 LAPTM5 STAB1 KCNU1 MPP1 TMEM176B ABCC5 TTYH3 MYO1F

4.58e-0819421910800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCellFetal_29-31_weeks-Immune-dendritic_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SCN11A HLA-DPA1 HLA-DRA SLC7A11 SYK HS3ST3B1 WDFY4 MYO1F RAB7B

1.35e-071652199d8b0a9b6f704b98e8f0412c11739879a26c036e2
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DZIP1L DGKH PROM1 DNAH9 WHRN DNAH3 NWD1 DNAH12 DNAH11

1.66e-07169219914aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 AKR1C2 PROM1 SLC44A5 UTRN CNTN4 LIPC DNAH17 DNAH11

2.34e-071762199327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 AKR1C2 PROM1 SLC44A5 UTRN CNTN4 LIPC DNAH17 DNAH11

2.45e-071772199da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HLA-DPA1 HLA-DRA SLC7A11 SYK HS3ST3B1 WDFY4 SLC20A1 MYO1F RAB7B

2.45e-071772199c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HLA-DPA1 HLA-DRA ME1 HNMT STAB1 TMEM176B ABCC5 TTYH3 TGFBR1

4.46e-071902199d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HLA-DPA1 HLA-DRA LAPTM5 STAB1 SYK MPP1 TMEM176B TTYH3 MYO1F

4.66e-07191219924d75b7e1d6fb9d24aa7844f584ee888a449841f
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

HLA-DRA ME1 HNMT LAPTM5 STAB1 SYK TTYH3 WDFY4 MYO1F

5.08e-071932199a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellMonocytes-C1QA+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HLA-DPA1 HLA-DRA ME1 HNMT STAB1 SYK MPP1 TMEM176B TTYH3

5.31e-0719421993e104e85574894c04791252d466d438fc809dde3
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DPA1 HLA-DRA ME1 LAPTM5 STAB1 SYK MPP1 TMEM176B TTYH3

5.31e-0719421997b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DPA1 HLA-DRA ME1 LAPTM5 STAB1 SYK MPP1 TMEM176B TTYH3

5.31e-071942199435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DPA1 HLA-DRA ME1 LAPTM5 STAB1 SYK MPP1 TMEM176B TTYH3

5.31e-07194219948c37251518f96524807b5bd1bbc2820637666ad
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HLA-DRA ME1 STAB1 SYK MPP1 TTYH3 WDFY4 MYO1F RAB7B

5.54e-071952199247803cf58c6d9c561a52aa34e581188ddad197e
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HLA-DPA1 HLA-DRA LAPTM5 STAB1 SYK MPP1 TMEM176B TTYH3 MYO1F

5.54e-071952199312d9625655b38f1a7c2bf8f8bb7b667ebdf9617
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL22 HLA-DPA1 HLA-DRA FXYD5 HNMT MPP1 TMEM176B TTYH3 RPL35

6.04e-071972199b17ac6c88dc53e54e04e8a79409d9a0de0be88dc
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL22 HLA-DPA1 HLA-DRA FXYD5 HNMT MPP1 TMEM176B TTYH3 RPL35

6.04e-071972199a9f8edeef73a5261d7661dd1987aaa5bf6183af8
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT172 DZIP1L PROM1 DNAH9 MAPK8IP1 DNAH3 NWD1 DNAH12 DNAH11

6.04e-07197219922c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT172 DZIP1L PROM1 DNAH9 MAPK8IP1 DNAH3 NWD1 DNAH12 DNAH11

6.04e-0719721993bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL22 HLA-DPA1 HLA-DRA FXYD5 HNMT MPP1 TMEM176B TTYH3 RPL35

6.04e-071972199a22c0f2ffac34635c9c8221aee778e2fc78d672b
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IFT172 DZIP1L PROM1 DNAH9 MAPK8IP1 DNAH3 NWD1 DNAH12 DNAH11

6.04e-07197219987db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcellseq2-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERBB2 ANKRD36C AKR1C1 AKR1C2 PROM1 BBOX1 SLC34A2 TGM2 AKR1C3

6.30e-071982199829377071f65016d31d09175a43c28e95532b404
ToppCellC_01|World / shred on cell type and cluster

HLA-DRA ABCB1 MPP1 SI OAT SLC7A9 ACE2 SLC10A2 SLC20A1

6.30e-07198219971d38084d09a96331877384ce6346f0de4bdcef9
ToppCellcellseq2-Epithelial-Epithelial_Glandular-SMG_Basal/Duct|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ERBB2 ANKRD36C AKR1C1 AKR1C2 PROM1 BBOX1 SLC34A2 TGM2 AKR1C3

6.30e-07198219927a3c1c5ac855dff8d63f44eaa289be3f5bd621a
ToppCellControl_saline-Epithelial_alveolar|Control_saline / Treatment groups by lineage, cell group, cell type

EPHB3 ABCA3 ME1 C5 UTRN TMEM176B AP1M2 SLC34A2 AKR1C3

6.30e-071982199532b7ef4ad46fe35ad2c6bdf89f70a17f1a2e2e2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKR1C1 FZD1 PROM1 TMEM176B TNC TTYH3 SLC47A2 ACE2 AKR1C3

6.30e-071982199be305d89d48c67ce922fa71aaf15e24d00c89ff6
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERBB2 NCALD ABCB1 UTRN AKR1C3 MACF1 SEPTIN7 ATP2B4 MVD

6.57e-0719921994820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCellproximal-Epithelial-Mucous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD36C AKR1C1 AKR1C2 PROM1 URB1 SLC44A5 KDR BBOX1 ZG16B

6.57e-071992199baac580484124b7c36717b607adcf2cb446e631d
ToppCellproximal-Epithelial-Mucous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD36C AKR1C1 AKR1C2 PROM1 URB1 SLC44A5 KDR BBOX1 ZG16B

6.57e-07199219915ba36fa6ad73d0e959e42f18d7acbc14e310dc9
ToppCell3'-Parenchyma_lung|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA3 HLA-DPA1 HLA-DRA FXYD5 LAPTM5 STXBP2 HPCAL1 DPYSL2 ARPC5

6.57e-071992199bc064ccfec8c1e96079b89b05aeebddf48bc87f3
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 HLA-DPA1 HLA-DRA LAPTM5 STAB1 UTRN TTYH3 WDFY4 MYO1F

6.57e-071992199f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPA1 HLA-DRA LAPTM5 STAB1 SYK UTRN TTYH3 WDFY4 MYO1F

6.57e-0719921995ceeed92f831d068ff4bb3994f420002338330e7
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERBB2 NCALD ABCB1 UTRN AKR1C3 MACF1 SEPTIN7 ATP2B4 MVD

6.57e-071992199eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ERBB2 NCALD ABCB1 UTRN AKR1C3 MACF1 SEPTIN7 ATP2B4 MVD

6.57e-07199219910c8729b779073c3bf808e85958d59147f0be5c5
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERBB2 NCALD ABCB1 UTRN AKR1C3 MACF1 SEPTIN7 ATP2B4 MVD

6.57e-071992199867fd292f3879982422e840e087bfdb3b21a8715
ToppCellproximal-3-Epithelial-Mucous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD36C AKR1C1 AKR1C2 PROM1 URB1 SLC44A5 KDR BBOX1 ZG16B

6.57e-0719921993018378860de084662be0cc46fce421db3bb9ec9
ToppCellControl-Lymphoid_T/NK-NK|Control / Disease group, lineage and cell class

ERBB2 NCALD ABCB1 UTRN AKR1C3 MACF1 SEPTIN7 ATP2B4 MVD

6.57e-07199219994b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DRA LAPTM5 STAB1 SYK MPP1 TMEM176B TTYH3 WDFY4 MYO1F

6.85e-072002199ad52b38df5c71f28829b04cd0e6b97f0f9f7610a
ToppCellmLN-B_cell-Follicular_B_cell|B_cell / Region, Cell class and subclass

RPL22 HLA-DPA1 HLA-DRA ABCB1 LAPTM5 CLCN4 SLC38A11 TAPT1 RPL35

6.85e-0720021998fbd27ffcfd0702ad3c340d32455e36a01617139
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

ERBB2 NCALD GBP4 SYT11 UTRN TGFBR1 AKR1C3 MACF1 ATP2B4

6.85e-0720021992281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCB1 FZD1 PROM1 TMEM176B TNC TTYH3 SLC47A2 ACE2 AKR1C3

6.85e-072002199105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCellBronchial_Biopsy-Immune-Mast_cells|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

HBS1L ABCA3 CTTNBP2 RYR3 MS4A2 SYT11 SLC38A11 EIF2S3B

1.89e-06168219845ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DPA1 HLA-DRA CLCN4 SCN5A WDFY4 TMEM132E MYO1F RAB7B

1.98e-061692198da3485d77bb7876fad4f166f6099e681b27457ae
ToppCell(5)_Dendritic_cell-(51)_cDC1|(5)_Dendritic_cell / shred on Cell_type and subtype

NCALD HLA-DPA1 CLCN4 WDFY4 LIPC RAB7B SPIDR

2.59e-061232197d46cfdf8b3e561d8db33903207d5151cdb2a91d4
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DZIP1L PROM1 DNAH9 MAPK8IP1 DNAH3 DNAI3 DNAH12 DNAH11

2.91e-0617821983b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCXD2 ITGA6 SSTR2 RYR3 ABCB1 OR51B5 HS3ST4 BBOX1

3.16e-061802198a499548391e6833b78f6e920f8e32a755814a9da
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN11A STAB1 KDR PCSK9 RALGPS2 LBP TGM2 ACMSD

3.43e-061822198d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 ABCA12 ITGA6 ME1 BBOX1 OAT SLC22A4 TANC1

3.57e-06183219826b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DPA1 HLA-DRA LAPTM5 MPP1 DPYSL2 TMEM176B TTYH3 RAB7B

3.57e-0618321984cc0961a67de76b8d756cd9ffcaa98e3fe3c3a69
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HLA-DPA1 HLA-DRA SLC7A11 LAPTM5 SYK WDFY4 MYO1F RAB7B

3.72e-061842198315bb14e848d8e8e4533122047df6f9b89b89d99
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

SORCS1 BBOX1 CNTN4 TTYH3 SLC47A2 ACE2 SLC22A5 ACMSD

3.72e-061842198dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell10x5'-GI_small-bowel-Myeloid_Dendritic-DC1|GI_small-bowel / Manually curated celltypes from each tissue

HLA-DPA1 HLA-DRA DZIP1L SYK WDFY4 TMEM132E H1-0 RAB7B

3.87e-06185219823ffba9216729b5bdb30b35742ba2627bb1200bf
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TSPAN12 NPSR1 PROM1 COL14A1 TMEM176B TNC TMEM132E

3.94e-0613121979ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DZIP1L MPDZ DNAH9 DNAH3 NWD1 DNAI3 DNAH12 DNAH11

4.03e-06186219876033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36C AKR1C1 AKR1C2 PROM1 ZG16B AP1M2 SLC34A2 ACE2

4.19e-06187219871d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCellNS-critical-d_16-33-Myeloid-Monocyte-derived_DC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HLA-DPA1 HLA-DRA HNMT STAB1 PCSK9 DPYSL2 TMEM176B RPL35

4.36e-06188219808eb1e4b719af53c52895557523d0a1b7421d849
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 DNAH14 PROM1 SLC44A5 UTRN CNTN4 LIPC DNAH11

4.36e-06188219863a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 AKR1C1 DNAH14 PROM1 SLC44A5 SLC38A11 CNTN4 DNAH11

4.53e-061892198904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PROM1 SLC44A5 CNTN4 TNC SLC34A2 LEPR RPL35 DNAH11

4.53e-061892198bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCellControl-Endothelial-Endothelial-Alv_Gen_Intermediate|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 NCALD CEP85L ITGA6 DGKH ABCB1 KDR LEPR

4.53e-0618921985d7ae1ead7f4fbaeec26f651833c9c2106e1e4d1
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL22 HLA-DPA1 HLA-DRA DPYSL2 TMEM176B TTYH3 RAB7B RPL35

4.53e-0618921980a490730cdc912d5233de59057550de0e4065747
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-B_lymphocytic-naive_B_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HLA-DPA1 HLA-DRA LAPTM5 CLCN4 SLC38A11 TAPT1 RALGPS2 RPL35

4.71e-061902198441770ce7b3c81f36f5b15b8e51794f736462457
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PROM1 DNAH9 DNAH3 NWD1 DNAI3 DNAH12 SLC22A4 DNAH11

4.71e-061902198a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CTTNBP2 PLCXD2 SORCS1 PTK2B SLC38A11 WHRN TMEM132E KCNIP4

4.71e-0619021981bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL22 NCALD HLA-DPA1 HLA-DRA DPYSL2 TMEM176B TTYH3 MALRD1

4.90e-06191219851535232e889db52a9b24e5696b1687e93dd7302
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

RYR3 PROM1 DNAH9 DNAH3 NWD1 SLC34A2 DNAH12 DNAH11

4.90e-061912198ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCell3'_v3-blood-Myeloid_Monocytic-Nonclassical_monocytes|blood / Manually curated celltypes from each tissue

HLA-DPA1 HLA-DRA FZD1 STXBP2 ZG16B TTYH3 TGM2 H1-0

4.90e-06191219844a797b39254cbfa5c2bad8155436adfd3019bb0
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

RYR3 PROM1 DNAH9 DNAH3 NWD1 SLC34A2 DNAH12 DNAH11

4.90e-0619121986228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36C AKR1C1 PROM1 KDR BBOX1 CNMD ZG16B AP1M2

5.09e-061922198bf187a57a559ab732bb815892af45ca922966ac6
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

HNMT LAPTM5 STAB1 SYK TTYH3 WDFY4 MYO1F SPIDR

5.09e-061922198a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DZIP1L PROM1 DNAH9 DNAH3 DNAI3 DNAH12 SLC22A4 DNAH11

5.09e-061922198be592e661367affced9ebe80849b466e6adb3a34
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6|TCGA-Stomach / Sample_Type by Project: Shred V9

ABCA12 NPSR1 ITGA6 SLC7A11 GMPS GBP4 PDZD8 CBFB

5.09e-0619221984e689bca7a242f8482e25f273656e2caba8821c0
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 NCALD CEP85L DGKH ABCB1 KDR TANC1 ATP2B4

5.29e-061932198a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PROM1 DNAH9 DNAH3 NWD1 DNAI3 DNAH12 SLC22A4 DNAH11

5.29e-061932198e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DZIP1L PROM1 DNAH9 DNAH3 DNAI3 DNAH12 SLC22A4 DNAH11

5.29e-0619321980b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellCOPD-Lymphoid-NK|Lymphoid / Disease state, Lineage and Cell class

NCALD SYK UTRN LIPC BRD7 MYO1F AKR1C3 MVD

5.29e-0619321980020249fa71afb500af73700543bb6f349be6b10
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 GBP7 ITGA6 DGKH ABCB1 KDR LEPR TANC1

5.49e-06194219858f069efdefa0366033764446b9d6ffd4a17807e
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HLA-DPA1 HLA-DRA LAPTM5 SYK RALGPS2 WDFY4 EIF2S3 RPL35

5.49e-061942198b700381f8337b4c6aa50d09ab5bfcd59f2fb2cf3
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HLA-DPA1 HLA-DRA LAPTM5 SYK RALGPS2 WDFY4 EIF2S3 RPL35

5.49e-06194219884aa5ca0356a06fce8799eb1bfa1c362bab34032
ToppCellB_cell_maturation-Naive_B_cell|B_cell_maturation / Lineage and Cell class

RPL22 HLA-DPA1 HLA-DRA FXYD5 LAPTM5 SLC38A11 RALGPS2 RPL35

5.49e-061942198adb6f9aff65276e0db1f8367149998938b8e4fb0
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPAN12 GBP7 ITGA6 DGKH ABCB1 KDR LEPR TANC1

5.49e-061942198bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellNS-critical-d_07-13-Myeloid-Non-resident_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HLA-DRA FXYD5 HNMT STAB1 MPP1 DPYSL2 TMEM176B TTYH3

5.70e-061952198ee8743d39996bb756f50db32748e8a902d3294b8
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ANKRD36C HNMT AKR1C1 AKR1C2 PROM1 KDR ZG16B ABCC5

5.70e-061952198b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP1L DNAH9 DNAH3 NWD1 DNAI3 DNAH12 SLC22A4 DNAH11

5.70e-0619521983486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellBL-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IFT172 PROM1 DNAH9 DNAH3 NWD1 DNAI3 DNAH12 DNAH11

5.70e-06195219807a6bcef6af93ed87df455dee624037cb75e011a
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Naive_B|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RPL22 HLA-DPA1 HLA-DRA FXYD5 LAPTM5 RALGPS2 WDFY4 RPL35

5.70e-061952198f00e6d000e107daed68d3ffa8948e1f6a41eb242
ToppCell356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|356C / Donor, Lineage, Cell class and subclass (all cells)

HLA-DPA1 HLA-DRA HNMT STAB1 TMEM176B ABCC5 TTYH3 TGFBR1

5.70e-0619521989231e929657542b78a6480d44402866511129c7f
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DZIP1L PROM1 DNAH9 DNAH3 NWD1 DNAI3 DNAH12 DNAH11

5.92e-061962198de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellMonocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

HLA-DPA1 HLA-DRA HNMT STAB1 SYK MPP1 TMEM176B TTYH3

5.92e-061962198ab0a8f5f388c9794d7f41f99fb0a5f2fd6fff6b3
ToppCellNS-moderate-d_16-33-Myeloid-Monocyte-derived_DC|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RPL22 HLA-DPA1 HLA-DRA LAPTM5 MPP1 DPYSL2 TMEM176B RPL35

5.92e-0619621986d056d8336df6b31065be6f7b041bf553fe7c521
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPL22 HLA-DPA1 HLA-DRA HNMT STAB1 DPYSL2 TMEM176B TTYH3

5.92e-0619621987ce416e1809bfbb39553c28c20125790100a938d
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

NCALD MPDZ DNAH9 DNAH3 DNAH12 MACF1 TANC1 DNAH11

5.92e-0619621986d02d494196e3f857d53eea46d9419690d43beca
ToppCellCOVID-19-lung-Macrophage_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

HLA-DRA LAPTM5 STAB1 SYK MPP1 TTYH3 WDFY4 MYO1F

5.92e-0619621981b7928f4eee94d4bb6ea410bab68a471dba12979
Drugflunisolide

AKR1C4 AKR1C1 AKR1C2 PGR TGM2 AKR1C3

1.07e-09132156ctd:C007734
Drugcloxazolam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.73e-0942154ctd:C005522
DrugPregnanes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.73e-0942154ctd:D011278
Drugtetralol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.73e-0942154ctd:C019106
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.73e-0942154ctd:C018156
DrugHydroxysteroids

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.84e-0852154ctd:D006914
Drugcresolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.84e-0852154ctd:C010092
DrugMedazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.14e-0762154ctd:D008472
DrugNitrazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.25e-0782154ctd:D009567
Drugtetrofosmin

BIRC6 SLC7A11 ABCB1 GMPS ABCB5

7.48e-07192155CID000004274
Drugcyclopentanol

AKR1C1 AKR1C2 AKR1C3

8.30e-0732153ctd:C016327
Drugcyclopentanone

AKR1C1 AKR1C2 AKR1C3

8.30e-0732153ctd:C007201
Drug5-dihydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

8.30e-0732153ctd:C454687
Drug4-benzoylbenzoic acid

AKR1C1 AKR1C2 AKR1C3

8.30e-0732153ctd:C058818
Drugdichloro(4-cymene)ruthenium(II)

AKR1C1 AKR1C2 AKR1C3

8.30e-0732153ctd:C530610
Drug4-hydroxybenzoic acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.39e-0792154ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

9.39e-0792154ctd:D004092
Drugbenzo(a)pyrene-7,8-dione

AKR1C4 AKR1C1 AKR1C2 ARNT AKR1C3

9.90e-07202155ctd:C076588
Drugbenzbromarone

AKR1C4 ABCB1 ABCB5 ABCC5 OAT SLC22A5

1.20e-06372156CID000002333
Drugoctyl gallate

AKR1C4 AKR1C1 AKR1C2 AKR1C3

1.55e-06102154ctd:C016627
DrugDihydroxydihydrobenzopyrenes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.42e-06112154ctd:D004101
Drugchlordecone alcohol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.42e-06112154CID000013946
Drugtetrahydrodeoxycorticosterone

AKR1C4 AKR1C1 AKR1C2

3.30e-0642153ctd:C009413
Drug9-methylphenazine-1-carboxylic acid

PGR ABCB1 ABCB5

3.30e-0642153CID004037810
Druggliquidone

AKR1C1 AKR1C2 AKR1C3

3.30e-0642153ctd:C010969
DrugDBD-H

AKR1C4 AKR1C1 AKR1C3

3.30e-0642153CID000131382
DrugPhenolphthalein

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.61e-06122154ctd:D020113
DrugAC1L45LU

ERBB2 SLC7A11 ABCB1 FANCD2 PTK2B KDR ABCB5 LBP TRAP1 ARNT H1-0

4.27e-0620521511CID000151069
DrugNorethindrone

AKR1C1 PGR ABCB1 FASN AKR1C3

4.88e-06272155ctd:D009640
DrugDMBA-3,4-dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

5.17e-06132154CID000050096
DrugDiazepam

ITGA6 AKR1C4 AKR1C1 AKR1C2 TNC TGFBR1 AKR1C3

6.39e-06742157ctd:D003975
DrugDydrogesterone

AKR1C1 AKR1C2 PGR AKR1C3

7.19e-06142154ctd:D004394
Drug5-alpha-Dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.19e-06142154ctd:D043582
Drug1-acenaphthenol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.19e-06142154CID000022750
DrugMeclofenamic Acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.19e-06142154ctd:D008469
DrugNSC86000

AKR1C1 AKR1C2 AKR1C3

8.19e-0652153CID000257630
Drugdrospirenone

AKR1C4 AKR1C1 AKR1C2 PGR

9.73e-06152154ctd:C035144
DrugPAK-104P

ABCB1 ABCB5 ABCC5 CCT4

9.73e-06152154CID000131368
Drugplatinum

TSPAN12 ERBB2 ABCB1 FANCD2 SCN10A ABCC5 CCT4 MSH2 RIF1 TRAP1

1.00e-0518321510CID000023939
Drugnaringenin

AKR1C1 PGR ABCB1 PROM1 ABCC5 SI ARNT AKR1C3

1.06e-051112158ctd:C005273
DrugBudesonide

AKR1C4 AKR1C1 AKR1C2 PGR ABCB1 TGM2 AKR1C3

1.08e-05802157ctd:D019819
Drugsodium

NACA2 ERBB2 SLC7A11 RYR3 PGR GMPS PHEX PTK2B ATP11B SCN5A PKD1 SCN10A HS3ST3A1 NSF SLC34A2 GRID1 CCT4 SLC7A9 SLC10A2 SLC20A1 SLC20A2 SLC22A4 SLC22A5 ATP2B4

1.08e-0594421524CID000000923
Drug17beta-estradiol glucuronide

ABCB1 ABCB5 ABCC5 OAT SLC10A2

1.17e-05322155CID000066424
DrugUrsodeoxycholic Acid

HLA-DRA GCKR AKR1C1 AKR1C2 PGR ABCB1 FASN TMEM176B TGM2 ARNT SLC10A2 AKR1C3

1.34e-0527621512ctd:D014580
DrugAC1L93E5

AKR1C4 AKR1C1 AKR1C3

1.63e-0562153CID000412383
DrugAC1L99H3

ABCB1 ABCB5 MSH2

1.63e-0562153CID000440540
DrugEstazolam

AKR1C1 AKR1C2 AKR1C3

1.63e-0562153ctd:D004949
Drug3-hydroxyhexobarbital

AKR1C4 AKR1C2 AKR1C3

1.63e-0562153CID000439898
DrugGlipizide

AKR1C1 AKR1C2 AKR1C3

1.63e-0562153ctd:D005913
Drugacenaphthene-1-ol

AKR1C1 AKR1C2 AKR1C3

1.63e-0562153ctd:C023723
Drugorthovanadate

SSTR2 ABCB1 PTK2B SYK DNAH9 DNAH3 NSF TNC ABCB5 ABCC5 ARNT DNAH17 ACMSD ATP2B4 DNAH11

1.80e-0543521515CID000061672
DrugOxprenolol hydrochloride [6452-73-9]; Up 200; 13.2uM; HL60; HT_HG-U133A

EPHB3 GCKR STAB1 PHEX COL14A1 TBCD TAPT1 TGM2 RIF1 PAX4

1.98e-05198215106145_UP
DrugRuthenium Compounds

AKR1C1 AKR1C2 PIM1 AKR1C3

2.13e-05182154ctd:D017975
Drugprobenecid

ABCA3 ABCB1 ABCB5 ABCC5 OAT SLC47A2 SLC10A2 SLC22A5

2.26e-051232158CID000004911
Drugquinocetone

AKR1C1 RYR3 CABLES1 PGR FASN PIM1 STXBP5L DNAH12 KCNIP4 ATP2B4 MVD

2.56e-0524821511ctd:C502851
Drugoxcarbazepine

AKR1C4 AKR1C1 AKR1C2 AKR1C3

2.68e-05192154ctd:C036006
Drug4-hydroxyequilenin-o-quinone

AKR1C1 AKR1C2 AKR1C3

2.83e-0572153ctd:C117714
Drugzomepirac

AKR1C1 AKR1C2 AKR1C3

2.83e-0572153ctd:C020549
Drugpuerarin

ITGA6 PGR GMPS PROM1 KDR ACE2

2.87e-05632156CID005281807
DrugChrysenes

AKR1C4 AKR1C1 AKR1C2 AKR1C3

3.33e-05202154ctd:D002911
DrugAC1L1IZE

RYR3 DNAH8 DNAH9 MAPK8IP1 DNAH3 DNAH17 ATP2B4 DNAH11

3.55e-051312158CID000004799
Drug20 alpha-dihydroprogesterone

AKR1C4 AKR1C1 AKR1C2 PGR AKR1C3

3.60e-05402155CID000008956
Drugvanadyl

SSTR2 ABCB1 PTK2B SYK DNAH8 DNAH9 DNAH3 NSF WRN DNAH17 ACMSD DNAH11

3.81e-0530721512CID000061671
DrugZidovudine

ABCA3 ME1 PGR ABCB1 FASN GBP4 TNC INPP5E ABCC5 SLC7A9 SLC20A1 SLC20A2 SLC22A4 SLC22A5 MVD HDLBP

3.87e-0552121516ctd:D015215
DrugBiliton

DNAH8 DNAH9 DNAH3 DNAH17 DNAH11

4.07e-05412155CID000002974
DrugLactic Acid

ME1 AKR1C1 LEPR ARNT AKR1C3

4.07e-05412155ctd:D019344
Drugo-quinone

AKR1C4 AKR1C1 AKR1C2 CLCN4 AKR1C3

4.07e-05412155CID000011421
DrugFlunitrazepam

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.08e-05212154ctd:D005445
Drugtesmilifene

ERBB2 PGR ABCB1 CCT4

4.08e-05212154CID000108092
DrugDutasteride

ERBB2 AKR1C1 AKR1C2 AKR1C3

4.08e-05212154ctd:D000068538
Drugchlordecone

AKR1C4 AKR1C1 AKR1C2 PGR AKR1C3 ATP2B4

4.08e-05672156CID000000299
Drug2-cyclohexen-1-ol

AKR1C4 AKR1C2 AKR1C3

4.49e-0582153CID000013198
DrugCocaine

SCN11A SCN5A SCN10A

4.49e-0582153DB00907
Drugw 77

NCALD ABCB1 ABCB5

4.49e-0582153CID003086590
DrugtXMP

ABCB1 ABCB5 ABCC5

4.49e-0582153CID003081384
Drugbenzene dihydrodiol

AKR1C4 AKR1C1 AKR1C2 AKR1C3

4.95e-05222154CID000000418
Druggeldanamicin

ERBB2 HLA-DRA SLC7A11 PGR ABCB1 PTK2B KDR GNL1 ABCB5 LBP TGM2 TRAP1 ARNT

5.90e-0537321513CID000003460
Drug2'-Monophosphoadenosine 5'-Diphosphoribose

ME1 AKR1C1 AKR1C2 AKR1C3

5.95e-05232154DB03461
DrugFoscarnet

PHEX SLC20A1 SLC20A2

6.69e-0592153ctd:D017245
DrugSo324

ABCB1 ABCB5 ABCC5

6.69e-0592153CID000462261
DrugMexiletine

ABCB1 SCN5A SCN10A

6.69e-0592153ctd:D008801
Drugverapamil

ABCA3 ABCA12 BIRC6 RYR3 ABCB1 PTK2B SCN5A PKD1 SCN10A ABCB5 ABCC5 ACE2 SLC22A4 SLC22A5 ATP2B4

7.01e-0549021515CID000002520
DrugGlycyrrhetinic Acid

AKR1C4 AKR1C1 AKR1C2 AKR1C3

7.08e-05242154ctd:D006034
Drug9,10-phenanthrenequinone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.37e-05252154ctd:C005399
DrugPregnanolone

AKR1C4 AKR1C1 AKR1C2 AKR1C3

8.37e-05252154ctd:D011280
DrugOxyphenbutazone [129-20-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A

ME1 SLC7A11 HS3ST3A1 WHRN RIF1 ARNT MYO1F AKR1C3 ATP2B4

8.48e-0519021596844_UP
DrugHypochlorous Acid

ME1 SLC7A11 STXBP2 PAPOLA HPCAL1 TBCD API5 TRAP1 USO1 SLC20A1 MYO1F RPL35 MVD

8.56e-0538721513ctd:D006997
DrugAC1L1J6H

ABCB1 PCSK9 MAPK8IP1 TMEM176B ABCB5 ABCC5 MSH2 PPP1R3A LIPC MVD

8.74e-0523621510CID000004889
Drugdiphenyltin oxide

TBP CCT4

8.88e-0522152CID000075280
DrugHexylcaine

SCN5A SCN10A

8.88e-0522152DB00473
Drugmesochlorin e6 monoethylenediamine

ABCB1 ABCB5

8.88e-0522152CID005488855
Drugalpha-methylcinnamic acid

AKR1C1 AKR1C3

8.88e-0522152ctd:C510582
Drugtaxuspine C

ABCB1 ABCB5

8.88e-0522152CID005321745
Drug2,2-diphenyl-1,3-dioxolane

ABCB1 ABCB5

8.88e-0522152CID000283230
DrugRo44-5912

ABCB1 ABCB5

8.88e-0522152CID000197370
DrugRiluzole

SLC7A11 SCN5A

8.88e-0522152DB00740
Drug8-(3,3-dimethylallyl)chrysin

ABCB1 ABCB5

8.88e-0522152CID005281903
DrugAC1L8LCS

ABCB1 ABCB5

8.88e-0522152CID000383419
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

8.88e-0522152DB07768
Drugsulfurmycin A

ABCB1 ABCB5

8.88e-0522152CID000155836
DiseaseColorectal Carcinoma

ABCA3 ABCA12 CABLES1 ABCB1 PROM1 KDR DNAH8 AGTPBP1 CNTN4 DNAH3 DPYSL2 ABCB5 WRN ABCC5 GRID1 MSH2 TGFBR1 TGM2 ARNT EXO1 SNRNP200

4.64e-0870221321C0009402
DiseaseColorectal Neoplasms

ABCA3 ABCA12 CABLES1 ABCB1 PROM1 KDR ABCB5 ABCC5 GRID1 MSH2 TGFBR1 ARNT EXO1

1.28e-0727721313C0009404
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2 AKR1C3

3.71e-0732133C0027661
DiseaseIntersex Conditions

AKR1C1 AKR1C2 AKR1C3

3.67e-0652133C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2 AKR1C3

3.67e-0652133C2930619
DiseaseHermaphroditism

AKR1C1 AKR1C2 AKR1C3

3.67e-0652133C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2 AKR1C3

3.67e-0652133C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2 AKR1C3

3.67e-0652133C0033804
DiseaseMalignant neoplasm of breast

ERBB2 ABCA3 CEP85L PGR ABCB1 SORCS1 FASN NAA25 PIM1 UTP20 KDR DNAH9 SYT3 CBFB LEPR PPP1R3A TGM2 RIF1 TRMT2A EXO1 MACF1 HDLBP

1.18e-05107421322C0006142
DiseaseDisorders of Sex Development

AKR1C1 AKR1C2 AKR1C3

1.27e-0572133C0036875
Diseasemetabolite measurement

GCKR AKR1C2 STAB1 SORCS1 SLC44A5 BBOX1 PCSK9 WDFY4 SLC7A9 LIPC SLC22A4 SLC22A5 AKR1C3 ACMSD DPY19L2P2

1.54e-0556021315EFO_0004725
DiseaseEndometrioma

AKR1C1 AKR1C2 PGR HS3ST3B1 TNC ARNT SLC20A1 AKR1C3

2.36e-051612138C0269102
DiseaseEndometriosis

AKR1C1 AKR1C2 PGR HS3ST3B1 TNC ARNT SLC20A1 AKR1C3

2.36e-051612138C0014175
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN11A SCN5A SCN10A

4.29e-05102133DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN11A SCN5A SCN10A

4.29e-05102133DOID:0080422 (implicated_via_orthology)
DiseaseTYPE 2 DIABETES MELLITUS

MAPK8IP1 PPP1R3A LIPC PAX4

4.72e-05282134125853
DiseaseType 2 diabetes mellitus

MAPK8IP1 PPP1R3A LIPC PAX4

4.72e-05282134cv:C0011860
DiseaseMALE PSEUDOHERMAPHRODITISM: DEFICIENCY OF TESTICULAR 17,20-DESMOLASE

AKR1C4 AKR1C2

5.19e-0522132C1839840
DiseaseMEHMO syndrome (implicated_via_orthology)

EIF2S3B EIF2S3

5.19e-0522132DOID:0060801 (implicated_via_orthology)
Disease46,XY disorder of sex development due to testicular 17,20-desmolase deficiency

AKR1C4 AKR1C2

5.19e-0522132cv:C1839840
Disease46,XY SEX REVERSAL 8

AKR1C4 AKR1C2

5.19e-0522132614279
Disease46,XY sex reversal 8 (is_implicated_in)

AKR1C4 AKR1C2

5.19e-0522132DOID:0111773 (is_implicated_in)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN11A SCN5A SCN10A

7.78e-05122133DOID:0060170 (implicated_via_orthology)
Diseasehexanoylcarnitine measurement

SLC44A5 SLC22A4 SLC22A5

7.78e-05122133EFO_0021040
Diseaseperipheral arterial disease, traffic air pollution measurement

VIT HPCAL1 PDZD8 UTRN STXBP5L TAF3 SLC10A2 MACF1

8.82e-051942138EFO_0004265, EFO_0007908
Diseasehomostachydrine measurement

HS3ST4 SLC22A4 SLC22A5

1.01e-04132133EFO_0021164
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

GCKR PCSK9 LIPC SLC22A4 SLC22A5 MACF1 CEACAM20

1.14e-041502137EFO_0004611, EFO_0020947
Diseaseasthma (is_implicated_in)

HLA-DPA1 HLA-DRA NPSR1 HNMT MS4A2 C5 TNC

1.51e-041572137DOID:2841 (is_implicated_in)
DiseaseAlcoholic Intoxication, Chronic

HLA-DRA NPSR1 MPDZ AKR1C4 HNMT PTK2B CNTN4 DPYSL2 AKR1C3

1.54e-042682139C0001973
DiseasePrimary Erythermalgia

SCN11A SCN10A

1.55e-0432132C0014805
DiseasePAROXYSMAL EXTREME PAIN DISORDER

SCN11A SCN10A

1.55e-0432132C1833661
Diseaseepilepsy (implicated_via_orthology)

SCN11A ITGA6 ABCB1 KCNU1 SCN5A SCN10A NSF

1.90e-041632137DOID:1826 (implicated_via_orthology)
DiseaseNodular glomerulosclerosis

DGKH KDR LEPR ACE2

2.17e-04412134C0017667
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

GCKR PCSK9 LIPC SLC22A5 CEACAM20 DNAH11

2.43e-041202136EFO_0004611, EFO_0004639
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

GCKR PCSK9 LIPC SLC22A4 MACF1 CEACAM20

2.54e-041212136EFO_0008595, EFO_0020943
Diseasetype 2 diabetes mellitus (is_implicated_in)

GCKR ABCB1 MAPK8IP1 LEPR PPP1R3A LIPC PAX4

2.55e-041712137DOID:9352 (is_implicated_in)
DiseaseDiabetic Nephropathy

DGKH KDR LEPR ACE2

2.86e-04442134C0011881
Diseasemonocyte chemotactic protein-2 measurement

PROM1 TAPT1

3.08e-0442132EFO_0010789
Diseaseacute myelomonocytic leukemia (is_implicated_in)

GMPS CBFB

3.08e-0442132DOID:0081082 (is_implicated_in)
DiseaseBrugada ECG Pattern

SCN5A SCN10A

3.08e-0442132C1721096
Disease1-stearoyl-2-docosahexaenoyl-GPE (18:0/22:6) measurement

GCKR LIPC

3.08e-0442132EFO_0800411
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

GCKR PCSK9 LIPC SLC22A4 MACF1 CEACAM20

3.30e-041272136EFO_0008595, EFO_0020947
Diseaseresponse to angiotensin-converting enzyme inhibitor, Cough

ABCB5 WRN TGFBR1 KCNIP4

3.40e-04462134EFO_0005325, HP_0012735
DiseaseMalignant Neoplasms

ERBB2 BIRC6 ABCB1 FASN KDR WRN

3.44e-041282136C0006826
Diseaseapolipoprotein B measurement

HBS1L HLA-DRA BBS1 GCKR ABCB1 PCSK9 AP1M2 ATXN1L LIPC SLC22A5 ACMSD CEACAM20 DNAH11 HDLBP

3.56e-0466321314EFO_0004615
Diseaselipoprotein measurement, phospholipid measurement

AKR1C4 GCKR PCSK9 LEPR LIPC

3.84e-04852135EFO_0004639, EFO_0004732
Diseasepolyunsaturated fatty acid measurement

AKR1C4 GCKR NAA25 PCSK9 LIPC DNAH11

3.90e-041312136EFO_0010733
Diseasefetal hemoglobin measurement

HBS1L PHEX OR51B5

4.48e-04212133EFO_0004576
Diseasetriglycerides to total lipids in medium LDL percentage

GCKR PCSK9 LIPC SLC22A5

4.69e-04502134EFO_0022334
Diseasecholesteryl esters to total lipids in IDL percentage

GCKR PCSK9 LIPC MACF1

4.69e-04502134EFO_0022247
Diseaselipid measurement, lipoprotein measurement

AKR1C4 GCKR PCSK9 LEPR LIPC

5.00e-04902135EFO_0004529, EFO_0004732
Diseaseeosinophil count

HBS1L HLA-DPA1 HLA-DRA ITGA6 DGKH GCKR SLC7A11 CABLES1 LAPTM5 PTK2B EPS15L1 NAA25 MDN1 DNAH3 MTERF1 ABCB5 ABCC5 PPP1R3A LIPC EXO1 SPIDR SNRNP200 HDLBP

5.04e-04148821323EFO_0004842
Diseaselevel of Phosphatidylcholine (15:0_18:1) in blood serum

GCKR LIPC

5.11e-0452132OBA_2045064
Diseasehyperinsulinism (implicated_via_orthology)

LEPR LIPC

5.11e-0452132DOID:2018 (implicated_via_orthology)
Diseasehereditary sensory neuropathy (implicated_via_orthology)

SCN11A CCT4

5.11e-0452132DOID:0050548 (implicated_via_orthology)
Diseaseleptin receptor measurement

GCKR LEPR

5.11e-0452132EFO_0004635
Diseasesleep apnea (is_marker_for)

TBP LEPR

5.11e-0452132DOID:0050847 (is_marker_for)
Diseaseserum metabolite measurement

HLA-DPA1 GCKR SLC7A11 SLC44A5 BBOX1 PCSK9 CNTN4 DPYSL2 SLC7A9 LIPC SLC10A2 SLC22A4 DNAH17 SLC22A5 AKR1C3 NIPAL1 KCNIP4

5.41e-0494521317EFO_0005653
DiseaseTPE interval measurement

RPL22 CEP85L SCN5A SCN10A

5.45e-04522134EFO_0004644
Diseasephospholipid measurement

AKR1C4 GCKR NAA25 PCSK9 LEPR LIPC

5.54e-041402136EFO_0004639
DiseaseDegenerative polyarthritis

AKR1C1 AKR1C2 DPYSL2 TGM2 TRAP1

5.81e-04932135C0029408
DiseaseOsteoarthrosis Deformans

AKR1C1 AKR1C2 DPYSL2 TGM2 TRAP1

5.81e-04932135C0086743
DiseaseImmunologic Deficiency Syndromes

MYSM1 C5 LEPR

5.90e-04232133C0021051
Diseaseomega-6 polyunsaturated fatty acid measurement

AKR1C4 GCKR PCSK9 LIPC SLC22A5 CEACAM20 DNAH11

5.97e-041972137EFO_0005680
Diseaselevel of Phosphatidylethanolamine (16:0_18:2) in blood serum

GCKR LIPC SLTM

6.71e-04242133OBA_2045136
DiseaseObesity

BBS1 ME1 FASN INPP5E LBP LEPR AKR1C3

7.55e-042052137C0028754
Diseasehypopituitarism (implicated_via_orthology)

EIF2S3B EIF2S3

7.63e-0462132DOID:9406 (implicated_via_orthology)
DiseaseCarditis

SLC22A4 SLC22A5

7.63e-0462132C0869523
Diseaselevel of Phosphatidylcholine (16:0_18:1) in blood serum

GCKR LIPC

7.63e-0462132OBA_2045070
Diseaseintercellular adhesion molecule 2 measurement

NAA25 LBP

7.63e-0462132EFO_0008163
Diseasecortolone glucuronide (1) measurement

AKR1C2 AKR1C3

7.63e-0462132EFO_0800552
DiseaseCoxsackievirus Infections

SLC22A4 SLC22A5

7.63e-0462132C0010246
Diseaselipopolysaccharide-binding protein measurement

LBP TGM2

7.63e-0462132EFO_0021894
DiseaseMyocarditis

SLC22A4 SLC22A5

7.63e-0462132C0027059
Diseasebrain measurement, hippocampal volume

UTP20 MALRD1

7.63e-0462132EFO_0004464, EFO_0005035
Diseaselow density lipoprotein particle size measurement

GCKR NAA25 PCSK9 LIPC

8.26e-04582134EFO_0008593
Diseasecomplex trait

IFT172 GCKR VIT CABLES1 PCSK9 LEPR LIPC MACF1

8.33e-042712138EFO_0010578
DiseaseWeight Gain

ME1 AKR1C2 LBP LEPR DNAH11

8.83e-041022135C0043094
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

GCKR PCSK9 LIPC MACF1 CEACAM20

9.23e-041032135EFO_0008595, EFO_0020944
Diseasecholesterol to total lipids in IDL percentage

GCKR PCSK9 LIPC MACF1

9.38e-04602134EFO_0022233
Diseaselipoprotein measurement

AKR1C4 GCKR NAA25 LEPR LIPC

1.01e-031052135EFO_0004732
Diseaselevel of Phosphatidylethanolamine (18:0_18:2) in blood serum

GCKR LIPC SLTM

1.06e-03282133OBA_2045139
Disease1-palmitoyl-GPE (16:0) measurement

GCKR LIPC

1.06e-0372132EFO_0800245
Diseaseelectrocardiography, PR interval

SCN5A SCN10A

1.06e-0372132EFO_0004327, EFO_0004462
DiseaseCongenital Pain Insensitivity

SCN11A SCN10A

1.06e-0372132C0002768
DiseaseHereditary Sensory Autonomic Neuropathy, Type 5

SCN11A SCN10A

1.06e-0372132C0020075
Diseasesmoking status measurement, inflammatory bowel disease

HLA-DRA WDFY4

1.06e-0372132EFO_0003767, EFO_0006527
Diseaseatrioventricular septal defect (implicated_via_orthology)

IFT172 DNAH11

1.06e-0372132DOID:0050651 (implicated_via_orthology)
DiseaseDiabetes Mellitus, Non-Insulin-Dependent

GCKR KCNU1 MAPK8IP1 LEPR PPP1R3A LIPC PAX4

1.17e-032212137C0011860
DiseaseChild Development Disorders, Specific

TBCD CNTN4 WDFY4

1.18e-03292133C0085997
DiseaseChild Development Deviations

TBCD CNTN4 WDFY4

1.18e-03292133C0085996
Diseasefibrinogen measurement

HLA-DRA LEPR SLC22A4 SLC22A5 HDLBP

1.19e-031092135EFO_0004623
Diseasediffuse plaque measurement

HBS1L AKR1C2 DNAH14 HPCAL1 SYK COL14A1 KDR HS3ST4 AGTPBP1 MTERF1 GRID1 MACF1 KCNIP4 DNAH11

1.30e-0375821314EFO_0010699
DiseaseDevelopmental Disabilities

TBCD CNTN4 WDFY4

1.30e-03302133C0008073
Diseaseasthma, cardiovascular disease

ERBB2 SLC22A4 SLC22A5

1.30e-03302133EFO_0000319, MONDO_0004979
DiseaseCrohn's disease (is_implicated_in)

HLA-DPA1 ABCB1 SLC22A5

1.30e-03302133DOID:8778 (is_implicated_in)
Diseasefree cholesterol measurement

GCKR PCSK9 LEPR LIPC CEACAM20

1.40e-031132135EFO_0008591
Diseasebutyrylcarnitine measurement

SLC22A4 SLC22A5

1.41e-0382132EFO_0020010
Diseaseacetylcarnitine measurement

SLC22A4 SLC22A5

1.41e-0382132EFO_0021038
Diseasehemoglobin A2 measurement

HBS1L OR51V1

1.41e-0382132EFO_0005845

Protein segments in the cluster

PeptideGeneStartEntry
RTTKNEVVGRLILGA

SYT11

386

Q9BT88
ILILVGQSRVLSKGV

ADGRB2

981

O60241
VGLAIRSKIADGSVK

AKR1C4

61

P17516
ALTGRILDLKTGTVK

ARNT

231

P27540
QLRSLTEILKGGVLI

ERBB2

141

P04626
AGRVQLETIIKSLKS

EPS15L1

521

Q9UBC2
GGTGITILIINLKKS

MS4A2

141

Q01362
NGSVLLSEIVGTIKL

AP1M2

186

Q9Y6Q5
VLVKIGLQSTRIGLK

BIRC6

3381

Q9NR09
ILRLTHVKTGGKISL

BAG5

131

Q9UL15
IVKESGGKLTRRLVN

BRD7

321

Q9NPI1
VGLAIRSKIADGSVK

AKR1C3

61

P42330
GLNLRIKSGETVALV

ABCB5

406

Q2M3G0
KLSISIALIGGSRVV

ABCA12

1486

Q86UK0
LSKDGKILTILIVQR

CEACAM20

116

Q6UY09
IDKIVTSLGLKIGAR

EFL1

316

Q7Z2Z2
EGRTKAVGTITKLLQ

GTPBP1

561

O00178
SQIKLSIKRLVTTGV

H1-0

66

P07305
TLLKRVTLVKVGGEV

CNTN4

411

Q8IWV2
GIIVGTVLIIKSLRS

HLA-DPA1

236

P20036
ALITKIGLQTEKVSR

DNAH11

3136

Q96DT5
RKLSIGIALIAGSKV

ABCA3

671

Q99758
LLTDVIGKDKVILGT

ACMSD

276

Q8TDX5
ATGVGKTLLVKRLQE

ARL16

31

Q0P5N6
KILSGLKSLQTVSGR

API5

196

Q9BZZ5
LVTRSGRLLGIITKK

CLCN4

726

P51793
AVLFITGIIILTSGK

FXYD5

151

Q96DB9
TVLINLGLIKVTEKG

DNAI3

871

Q8IWG1
IRTVSGIRGQIKKAL

BMS1

1061

Q14692
RVSFLVTKGGSQILL

AGTPBP1

101

Q9UPW5
VLQGKLTRLAVQIGK

ATP2B4

351

P23634
VKDRAGSIVLKVLIS

ARPC5

71

O15511
QRKLLFTGLVSGVVL

NWD1

1266

Q149M9
LLLSATSGEKGVRIK

RBM28

506

Q9NW13
GSLTKAKVLITVLDV

PCDHGA7

326

Q9Y5G6
LIIVGAIGVGKTSLL

RAB7B

11

Q96AH8
AVIKRLISVLNKSTG

HBS1L

611

Q9Y450
RIGIKKAITANISIG

ABCB1

286

P08183
VTKAGAILVVTKLLR

MON1B

496

Q7L1V2
KKVSLLNIATRITGG

ANKRD36C

661

Q5JPF3
GIRKDAKGISIQTLR

DZIP1L

471

Q8IYY4
IIKTILKVKSSGGRA

OR9I1

221

Q8NGQ6
VGIQGLVLALVKSVT

KIAA0100

611

Q14667
VSVKGISISVNLLLG

LBP

131

P18428
SVKSEEVLRGLGKLI

MDN1

3461

Q9NU22
IIIGVKKGGTRALLE

HS3ST3B1

141

Q9Y662
SKGLIVKGRASLTQE

ME1

336

P48163
RIVSQIKTKGALGIS

INPP5E

396

Q9NRR6
TLIIFGKRTLSNGEV

NPSR1

181

Q6W5P4
RITSDRLLIKGGKIV

DPYSL2

11

Q16555
LEISVRGVKIGVKAD

MAPK8IP1

611

Q9UQF2
IVLIGSKTNGKFLIR

SYK

181

P43405
KGAIIQLATGELKRV

ATXN1L

471

P0C7T5
QLRDISSIGLKTVIG

CAND1

101

Q86VP6
RIGDTKSEIKILSIG

HNMT

46

P50135
VSGTLIGLEFIRKSQ

PCSK9

261

Q8NBP7
TSVLTNTRVVKIGLG

OR51B5

131

Q9H339
VLTLKTVLGIVSRGE

OR51H1

221

Q8NH63
TNSRIIKIGLTIIGR

OR51V1

146

Q9H2C8
LIAIGGVKITSTLQV

PDZD8

416

Q8NEN9
TKLTVGSLGLGLIII

PDZD9

31

Q8IXQ8
VRVSQLLAVTGKKTT

CBFB

166

Q13951
GARISIEGTVKLKTI

DNAH8

101

Q96JB1
IIALSVTSRGKLEQK

HPCAL1

86

P37235
IKGLSILLRGTVQEK

KCNIP4

146

Q6PIL6
GKLSKQTRTTLGALV

DNAH12

1151

Q6ZR08
ARGQILKILTGKIVV

ISG20L2

246

Q9H9L3
KELGKRTGTVQVLKR

MACF1

2836

O94854
SGLVLKTIRVKAGET

LIPC

446

P11150
RVLILVVSAEKKLTG

MVD

196

P53602
GRREVFVAIKTLKVG

EPHB3

656

P54753
GVTSIKKRESGVLLT

LEPR

1081

P48357
QGRKLLIIGTTSRKD

NSF

636

P46459
AKTKTLREGIIVTGK

GBP4

291

Q96PP9
AKTKTLREGILVTGN

GBP7

276

Q8N8V2
VGKSSLINGLVGRKV

GNL1

371

P36915
LINGLVGRKVVSVSR

GNL1

376

P36915
IIIGVKKGGTRALLE

HS3ST3A1

156

Q9Y663
QIIKGTGIILELFTS

KCNU1

56

A8MYU2
AKAKVVIELLLSVSG

ITGA6

826

P23229
GTIILKFLTSKILGV

DPY19L2

436

Q6NUT2
VKRILQGIKELGRST

DGKH

1201

Q86XP1
RGKKVSVTLASTLGL

MACF1

2421

Q9UPN3
LGKRTGTVQVLKRSG

MACF1

6711

Q9UPN3
VLEEIKLISKTGGQR

MOCS1

616

Q9NZB8
KVSEGGLNVTLTIRL

PCBP3

36

P57721
KRIVVKLGSAVVTRG

ALDH18A1

71

P54886
VIVKNLSSGTRVVLK

IFT172

336

Q9UG01
ILKVSNGCVSKILGR

PAX4

46

O43316
LLGSTSIKGIIRVLN

PPP1R3A

136

Q16821
VAAGKKRVIVIGISV

GCKR

166

Q14397
VGLVESKIRILVGSL

PAPOLA

391

P51003
ELIKAIGLRQKGVVS

PGR

851

P06401
ATGSIQILIKTEKGL

MALRD1

1606

Q5VYJ5
LILKAIRGVVFVKGT

ABCC5

926

O15440
RVAKLLSIVALVGGV

PRRT2

311

Q7Z6L0
AIKTITILALGQVDG

FZD1

456

Q9UP38
LFRIRSVIKQGGTKT

FZD5

426

Q13467
LSFIKILLKRGGVRV

ERVK-5

16

Q9HDB9
ILLKRGGVRVSTKNL

ERVK-5

21

Q9HDB9
KALLSVGVSKRSNIV

EBLN1

91

P0CF75
KERVGTSKVLVLLSG

GMPS

231

P49915
SELRIILVGKTGTGK

GIMAP2

21

Q9UG22
RQSTGAVSLKEIIGL

CABLES1

371

Q8TDN4
LRAIKSVLVVAGSLK

DNAH17

2021

Q9UFH2
IVQLVRGKLSSGARL

DNAH3

1321

Q8TD57
IKLLLEAGTNRSVKT

CTTNBP2

826

Q8WZ74
RTGVSKIGILITDGK

COL14A1

256

Q05707
LQKELGLISGISIIV

SLC7A9

26

P82251
TEIKRILSVKGLLVG

C5

971

P01031
LSTLKKVGIVRLTGA

BBOX1

141

O75936
GIVILIFTGIRDRKK

ACE2

756

Q9BYF1
IGKAKALTSQLRTIG

CEP85L

186

Q5SZL2
IIIGTIFIIKGLRKS

HLA-DRA

231

P01903
GGKTTVRRILEKALT

DNAH14

1431

Q0VDD8
GSRLQGLTLKVVTVL

GRID1

431

Q9ULK0
RVAIILLKEGSKAIG

SLC44A5

351

Q8NCS7
GNIKILITTDIVSRG

DDX53

516

Q86TM3
KRKTLVLIGASGVGR

MPP1

281

Q00013
AIKSVLVVAGSLKRG

DNAH9

2046

Q9NYC9
RVSAVKADLGKIVLT

EIF2S3B

416

Q2VIR3
KVIIGTKTILANGAL

EIF2B2

231

P49770
KNVGLTLRKLIGSVD

PTK2B

911

Q14289
EGVVAVLLTKKSLAR

FASN

226

P49327
TTRGGGLIIKILKRT

BBS1

391

Q8NFJ9
SNKGISDIIKVLVLR

BBS1

556

Q8NFJ9
LLGAKVSETIRKGLI

SLC20A1

76

Q8WUM9
LLGAKVGETIRKGII

SLC20A2

61

Q08357
ILGKSVRIIFSTLGV

SLC22A4

221

Q9H015
ILGKSVRIIFSTLGV

SLC22A5

221

O76082
RNIAKLGKVSLISTG

SLC38A11

116

Q08AI6
IIQRGGILITERKKA

MSH2

216

P43246
IIALSVTSRGKLEQK

NCALD

86

P61601
LIIGVKKGGTRALLE

HS3ST4

201

Q9Y661
VSSVKGLGIAIKELI

NIPAL1

251

Q6NVV3
GTIILKFLTSKILGV

DPY19L2P2

246

Q6ZN68
LLKISGIILKTGESQ

FANCD2

51

Q9BXW9
LLRLLITKGAKVNGR

MPHOSPH8

616

Q99549
VLVTSIKVNGSLGLE

PKD1

1466

P98161
IVGRKIGKIRSSAFL

PRR14L

1536

Q5THK1
IISTILKIASVEGRK

OR10J1

231

P30954
GAVTIQGVLRRKTLL

RALGPS2

456

Q86X27
KIILKIGSIAGAILI

SLC10A2

191

Q12908
RSLIRKSGLVVLGQE

NTMT2

246

Q5VVY1
GTRGVVALQTLRKLV

PNPLA8

451

Q9NP80
VLLKKVSSGFSGVIR

PIM1

91

P11309
GRLTVTIIKASNLKA

SYT3

446

Q9BQG1
GKLRIAKTQGRTEVS

GTF2F2

41

P13984
LTLRVGAGQDKIVIS

TAF3

761

Q5VWG9
ILSQGSKIQTRVGLL

USO1

481

O60763
RAQVSKELGILSKIS

UTP20

1326

O75691
GRTGKIRVQSLKIGL

UTRN

2946

P46939
LIKKGVLITAVVEVG

RNF133

166

Q8WVZ7
VGKLLIRKSGRVQLL

POLR3D

326

P05423
IRKSGRVQLLLGKVT

POLR3D

331

P05423
IGLALARKVKRVIGV

TRMT2A

446

Q8IZ69
VTGGAASKLSKIRVV

RPL35

36

P42766
VGISLVLGTLISILK

SLC47A2

376

Q86VL8
TLRVKAKKGVTLLGT

TMEM132E

331

Q6IEE7
ISLSLLIGVVKNREK

LAPTM5

76

Q13571
LIRAKNIKTIGDLST

RIF1

2321

Q5UIP0
LGTIISRTAKLIVAG

NEO1

136

Q92859
TTVVAGIKRVLNSIG

PROM1

376

O43490
ITGVKTVLISRLKQA

SLTM

41

Q9NWH9
SVISGLKTIVGALIQ

SCN5A

231

Q14524
NTSVVVALLRKGAKL

TANC1

1256

Q9C0D5
SGITRVEKAKIGLIQ

CCT4

236

P50991
LVRVKKSAATLGIAI

WHRN

816

Q9P202
RGKLGKVALIQLCVS

WRN

91

Q14191
LQKTTGKRGIVISRS

SI

1471

P14410
LVTVLGNLGLITLIK

OR8U3

36

Q8NH85
IIIKVKSSGIRVGSS

SSTR2

231

P30874
TVGVERVISTKGLNL

EXO1

396

Q9UQ84
SKLLKGVISEQGLRE

URB1

581

O60287
VRGKGLLNAIVIKET

OAT

371

P04181
LKVIVSLVSLGVGLR

TMEM176B

216

Q3YBM2
VQKILAIGTRTGAIR

STXBP5L

81

Q9Y2K9
IARTIVLQESIGKGR

TGFBR1

201

P36897
VGLAIRSKIADGSVK

AKR1C1

61

Q04828
VGLAIRSKIADGSVK

AKR1C2

61

P52895
KVGAVVLISGAVLLL

CNMD

41

O75829
KITLLREISLKTGIQ

CLUH

926

O75153
VVRSGGLVKTRSKNI

ATP11B

126

Q9Y2G3
GLVKTRSKNIRVGDI

ATP11B

131

Q9Y2G3
ILGSVLKGQVATVIK

SLC34A2

386

O95436
TAGTLLQKLRAKGIR

PIAS3

281

Q9Y6X2
INRSLIVGLKISTKS

TGM2

416

P21980
IVGLKISTKSVGRDE

TGM2

421

P21980
VITGLAARKTTGIRK

FYTTD1

101

Q96QD9
KRKVTLLRGVSIIIG

SLC7A11

41

Q9UPY5
GLRVSVGLLLVKSVQ

ZG16B

76

Q96DA0
LGKQVRSLKALVITI

TMEM199

136

Q8N511
GTLLLSRLIKISGTQ

TDRKH

166

Q9Y2W6
IIGGKATGVIVKTIL

MPDZ

271

O75970
VKTIARGLVGGLKNT

PLCXD2

271

Q0VAA5
LSGRKSGVLTVKILE

SPIDR

291

Q14159
VIQGLVKDRSIFTGL

WDR75

326

Q8IWA0
IQTGKGEAIRIRSIL

RYR3

2306

Q15413
IVTVSLLELGVAKKG

SCN10A

736

Q9Y5Y9
SKVLIKEGGVQLLLT

SEPTIN7

96

Q16181
VLLIFVSGKVVLTGA

TBP

301

P20226
VSGKVVLTGAKVRAE

TBP

306

P20226
LKAVVGEKILSGVIR

STXBP2

6

Q15833
LALATEGGVLKKVIR

TNC

16

P24821
TVDGTKTQTRLVKLI

TNC

1756

P24821
VVTLLKGSVRNAVVL

WDFY4

551

Q6ZS81
LKTAIEKITQRGGLS

VIT

356

Q6UXI7
ISTLKSRIKELVNAG

MTERF1

356

Q99551
TGKKANRGTRIALVV

PHEX

11

P78562
GVLLEKVAATLKTLV

PRAMEF10

341

O60809
LGGGVVTIERSKSKI

RPL22

56

P35268
HGQLTVEKLISKGRI

STAB1

581

Q9NY15
GTKQLQVLRFLGISI

TSPAN12

216

O95859
LNAKTKVRGLIEIIS

SNRNP200

1836

O75643
GVRTGTKIIIHLKSD

TRAP1

246

Q12931
KVIIGFVLKRSLTNV

ZNF818P

51

Q6ZRF7
KAISVVSRLKVIVGA

SCN11A

231

Q9UI33
VIVGALLRSVKKLVN

SCN11A

241

Q9UI33
VLLIRVVTSSIKVQG

TAPT1

411

Q6NXT6
TLLRKLGVKLVQRLG

TBCD

291

Q9BTW9
LLKLIEIGVQTGSTA

KDR

1326

P35968
KIIGRKGAVITQIRL

HDLBP

1066

Q00341
IGRVIKKSLVEATGV

SORCS1

1001

Q8WY21
LLTLEGRTGTNEKKI

ZNF777

206

Q9ULD5
TVVTGGEVKKLKRLT

TRAV27

66

A0A087WT01
LVLVGLIRSSKGILV

TTYH3

226

Q9C0H2
RVSAVKADLGKIVLT

EIF2S3

416

P41091
LAVLKVGGRTLTVSV

MYO1F

901

O00160
SKLGLLQVTGVTRVT

NACA2

81

Q9H009
KLGLQQVTGVTRVTI

NACA4P

81

Q9BZK3
IRGKLGEKLTSEIQS

NAA25

216

Q14CX7
TKISKLIGSRTVLQV

MYSM1

141

Q5VVJ2