Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H2AXS139 kinase activity

ATR PRKDC ATM

7.44e-083853GO:0035979
GeneOntologyMolecularFunctionhistone H2AX kinase activity

ATR PRKDC ATM

7.40e-075853GO:0141003
GeneOntologyMolecularFunctionplus-end-directed microtubule motor activity

KIF5B KIF5C KIF3A

4.85e-0517853GO:0008574
GeneOntologyMolecularFunctionmicrotubule binding

APC TRIM54 CDK5RAP2 KIF5B KIF5C SKA3 CAMSAP1 KIF3A

5.03e-05308858GO:0008017
GeneOntologyMolecularFunctionDNA-dependent protein kinase activity

PRKDC ATM

5.36e-053852GO:0004677
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PIK3CD PI4KA ATM

1.80e-0426853GO:0052742
GeneOntologyMolecularFunctionhistone kinase activity

ATR PRKDC ATM

2.26e-0428853GO:0035173
GeneOntologyMolecularFunctionchromatin insulator sequence binding

ZFX ZFY

3.71e-047852GO:0043035
GeneOntologyMolecularFunctioncalmodulin binding

UBR4 CDK5RAP2 UNC13C CAMK1 MYO15A CAMSAP1

4.48e-04230856GO:0005516
GeneOntologyMolecularFunctiontubulin binding

APC TRIM54 CDK5RAP2 KIF5B KIF5C SKA3 CAMSAP1 KIF3A

4.75e-04428858GO:0015631
GeneOntologyMolecularFunctionlipid kinase activity

PIK3CD PI4KA ATM

7.06e-0441853GO:0001727
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase activity

PIK3CD ATM

9.61e-0411852GO:0016303
GeneOntologyMolecularFunctionubiquitin protein ligase activity

TRIM73 UBR4 TRIM55 TRIM63 TRIM54 UBR3 TRIM74

1.05e-03372857GO:0061630
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN1 EFEMP2

1.15e-0312852GO:0030023
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

TRIM73 UBR4 TRIM55 TRIM63 TRIM54 UBR3 TRIM74

1.54e-03398857GO:0061659
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN1 EFEMP2

1.58e-0314852GO:0097493
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF5B KIF5C MYO15A KIF3A

1.62e-03118854GO:0003774
GeneOntologyMolecularFunctionadenylate cyclase binding

RAF1 ADCY2

2.07e-0316852GO:0008179
GeneOntologyMolecularFunctioncytoskeletal protein binding

NCKIPSD KCNMA1 APC TRIM63 TRIM54 CDK5RAP2 KIF5B KIF5C SKA3 MYO15A CAMSAP1 KIF3A

2.33e-0310998512GO:0008092
GeneOntologyMolecularFunctionsulfur compound binding

GSTM5 FBN1 TFB1M SETD6 EFEMP2 RSPO1

2.56e-03323856GO:1901681
GeneOntologyBiologicalProcesscell cycle checkpoint signaling

ATR INCENP APC CDK5RAP2 PRKDC ATM TP53BP1 ZFY KNL1

2.24e-07217839GO:0000075
GeneOntologyBiologicalProcessnegative regulation of cell cycle phase transition

ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM TP53BP1 ZFY KNL1

4.84e-073118310GO:1901988
GeneOntologyBiologicalProcessnegative regulation of nuclear division

INCENP APC CDK5RAP2 ATM ZFY KNL1

4.85e-0773836GO:0051784
GeneOntologyBiologicalProcessestablishment of organelle localization

GBF1 INCENP PIK3CD APC CDK5RAP2 UNC13C KIF5B ATM KIF5C SKA3 KIF3A KNL1

1.84e-065468312GO:0051656
GeneOntologyBiologicalProcessmitotic spindle assembly checkpoint signaling

INCENP APC CDK5RAP2 ATM KNL1

1.90e-0651835GO:0007094
GeneOntologyBiologicalProcessspindle assembly checkpoint signaling

INCENP APC CDK5RAP2 ATM KNL1

1.90e-0651835GO:0071173
GeneOntologyBiologicalProcessnegative regulation of cell cycle process

ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM TP53BP1 ZFY KNL1

1.91e-063628310GO:0010948
GeneOntologyBiologicalProcessanterograde dendritic transport of neurotransmitter receptor complex

KIF5B KIF5C KIF3A

2.17e-067833GO:0098971
GeneOntologyBiologicalProcessnegative regulation of mitotic metaphase/anaphase transition

INCENP APC CDK5RAP2 ATM KNL1

2.30e-0653835GO:0045841
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid segregation

INCENP APC CDK5RAP2 ATM KNL1

2.30e-0653835GO:0033048
GeneOntologyBiologicalProcessnegative regulation of sister chromatid segregation

INCENP APC CDK5RAP2 ATM KNL1

2.30e-0653835GO:0033046
GeneOntologyBiologicalProcessnegative regulation of mitotic sister chromatid separation

INCENP APC CDK5RAP2 ATM KNL1

2.30e-0653835GO:2000816
GeneOntologyBiologicalProcessmitotic spindle checkpoint signaling

INCENP APC CDK5RAP2 ATM KNL1

2.30e-0653835GO:0071174
GeneOntologyBiologicalProcessnegative regulation of metaphase/anaphase transition of cell cycle

INCENP APC CDK5RAP2 ATM KNL1

2.77e-0655835GO:1902100
GeneOntologyBiologicalProcessnegative regulation of chromosome separation

INCENP APC CDK5RAP2 ATM KNL1

2.77e-0655835GO:1905819
GeneOntologyBiologicalProcessnegative regulation of mitotic cell cycle phase transition

ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM KNL1

2.83e-06219838GO:1901991
GeneOntologyBiologicalProcessspindle checkpoint signaling

INCENP APC CDK5RAP2 ATM KNL1

3.32e-0657835GO:0031577
GeneOntologyBiologicalProcessnegative regulation of chromosome segregation

INCENP APC CDK5RAP2 ATM KNL1

3.32e-0657835GO:0051985
GeneOntologyBiologicalProcessmitotic cell cycle checkpoint signaling

ATR INCENP APC CDK5RAP2 PRKDC ATM KNL1

4.24e-06163837GO:0007093
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid segregation

INCENP APC CDK5RAP2 ATM KNL1

4.29e-0660835GO:0033047
GeneOntologyBiologicalProcessnegative regulation of mitotic nuclear division

INCENP APC CDK5RAP2 ATM KNL1

5.91e-0664835GO:0045839
GeneOntologyBiologicalProcessregulation of mitotic sister chromatid separation

INCENP APC CDK5RAP2 ATM KNL1

5.91e-0664835GO:0010965
GeneOntologyBiologicalProcessregulation of cell cycle phase transition

KLF11 ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM TP53BP1 ZFY KNL1

6.86e-065168311GO:1901987
GeneOntologyBiologicalProcessmitotic sister chromatid separation

INCENP APC CDK5RAP2 ATM KNL1

7.42e-0667835GO:0051306
GeneOntologyBiologicalProcessaxo-dendritic protein transport

KIF5B KIF5C KIF3A

1.01e-0511833GO:0099640
GeneOntologyBiologicalProcessanterograde dendritic transport

KIF5B KIF5C KIF3A

1.35e-0512833GO:0098937
GeneOntologyBiologicalProcesstelomerase catalytic core complex assembly

ATR ATM

1.60e-052832GO:1904868
GeneOntologyBiologicalProcesspositive regulation of telomerase catalytic core complex assembly

ATR ATM

1.60e-052832GO:1904884
GeneOntologyBiologicalProcessregulation of telomerase catalytic core complex assembly

ATR ATM

1.60e-052832GO:1904882
GeneOntologyBiologicalProcessregulation of chromosome separation

INCENP APC CDK5RAP2 ATM KNL1

1.67e-0579835GO:1905818
GeneOntologyBiologicalProcessnegative regulation of cell cycle

ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM TP53BP1 ZFY KNL1

1.69e-054648310GO:0045786
GeneOntologyBiologicalProcessnegative regulation of mitotic cell cycle

ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM KNL1

1.80e-05282838GO:0045930
GeneOntologyBiologicalProcessorganelle localization

GBF1 INCENP PIK3CD APC CDK5RAP2 UNC13C KIF5B ATM KIF5C SKA3 KIF3A KNL1

2.36e-057038312GO:0051640
GeneOntologyBiologicalProcesschromosome separation

INCENP APC CDK5RAP2 ATM KNL1

2.82e-0588835GO:0051304
GeneOntologyBiologicalProcessregulation of mitotic cell cycle phase transition

KLF11 ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM KNL1

3.42e-05402839GO:1901990
GeneOntologyBiologicalProcessregulation of mitotic metaphase/anaphase transition

INCENP APC CDK5RAP2 ATM KNL1

4.07e-0595835GO:0030071
GeneOntologyBiologicalProcessmicrotubule-based protein transport

KIF5B KIF5C KIF3A

4.10e-0517833GO:0099118
GeneOntologyBiologicalProcessprotein transport along microtubule

KIF5B KIF5C KIF3A

4.10e-0517833GO:0098840
GeneOntologyBiologicalProcesscell cycle phase transition

KLF11 ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM TP53BP1 ZFY KNL1

4.16e-056278311GO:0044770
GeneOntologyBiologicalProcessregulation of metaphase/anaphase transition of cell cycle

INCENP APC CDK5RAP2 ATM KNL1

4.73e-0598835GO:1902099
GeneOntologyBiologicalProcessestablishment of RNA localization to telomere

ATR ATM

4.79e-053832GO:0097694
GeneOntologyBiologicalProcessestablishment of protein-containing complex localization to telomere

ATR ATM

4.79e-053832GO:0097695
GeneOntologyBiologicalProcessmetaphase/anaphase transition of mitotic cell cycle

INCENP APC CDK5RAP2 ATM KNL1

5.21e-05100835GO:0007091
GeneOntologyBiologicalProcessdendritic transport

KIF5B KIF5C KIF3A

5.81e-0519833GO:0098935
GeneOntologyBiologicalProcessmetaphase/anaphase transition of cell cycle

INCENP APC CDK5RAP2 ATM KNL1

6.00e-05103835GO:0044784
GeneOntologyBiologicalProcessregulation of nuclear division

INCENP APC CDK5RAP2 ATM ZFY KNL1

6.84e-05172836GO:0051783
GeneOntologyBiologicalProcessnegative regulation of chromosome organization

INCENP APC CDK5RAP2 ATM KNL1

7.20e-05107835GO:2001251
GeneOntologyBiologicalProcessregulation of microtubule polymerization or depolymerization

APC TRIM54 CDK5RAP2 SKA3 CAMSAP1

7.53e-05108835GO:0031110
GeneOntologyBiologicalProcessattachment of spindle microtubules to kinetochore

INCENP APC SKA3 KNL1

7.63e-0556834GO:0008608
GeneOntologyBiologicalProcessregulation of sister chromatid segregation

INCENP APC CDK5RAP2 ATM KNL1

8.57e-05111835GO:0033045
GeneOntologyBiologicalProcessubiquitin-dependent protein catabolic process via the N-end rule pathway

UBR4 UBR3

9.55e-054832GO:0071596
GeneOntologyBiologicalProcessregulation of mitotic spindle checkpoint

INCENP CDK5RAP2 KNL1

1.05e-0423833GO:1903504
GeneOntologyBiologicalProcessregulation of mitotic cell cycle spindle assembly checkpoint

INCENP CDK5RAP2 KNL1

1.05e-0423833GO:0090266
GeneOntologyBiologicalProcessthymus development

RAF1 APC PRKDC ATM

1.07e-0461834GO:0048538
GeneOntologyBiologicalProcessregulation of mitotic cell cycle

KLF11 GBF1 ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM KNL1

1.34e-045948310GO:0007346
GeneOntologyBiologicalProcessestablishment of chromosome localization

INCENP APC ATM SKA3 KNL1

1.34e-04122835GO:0051303
GeneOntologyBiologicalProcessregulation of spindle checkpoint

INCENP CDK5RAP2 KNL1

1.53e-0426833GO:0090231
GeneOntologyBiologicalProcesschromosome localization

INCENP APC ATM SKA3 KNL1

1.80e-04130835GO:0050000
GeneOntologyBiologicalProcessmitotic cell cycle phase transition

KLF11 ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM KNL1

2.06e-04509839GO:0044772
GeneOntologyBiologicalProcessregulation of mitotic nuclear division

INCENP APC CDK5RAP2 ATM KNL1

2.08e-04134835GO:0007088
GeneOntologyBiologicalProcessmitotic sister chromatid segregation

INCENP APC CDK5RAP2 ATM SKA3 KNL1

2.15e-04212836GO:0000070
GeneOntologyBiologicalProcessnuclear division

INCENP APC CDK5RAP2 ATM SKA3 RSPO1 ZFY KNL1 FANCA

2.15e-04512839GO:0000280
GeneOntologyBiologicalProcessplus-end-directed vesicle transport along microtubule

KIF5B KIF3A

2.37e-046832GO:0072383
GeneOntologyBiologicalProcesstelomerase holoenzyme complex assembly

ATR ATM

2.37e-046832GO:1905323
GeneOntologyBiologicalProcessregulation of chromosome segregation

INCENP APC CDK5RAP2 ATM KNL1

2.46e-04139835GO:0051983
GeneOntologyBiologicalProcessnegative regulation of organelle organization

INCENP APC TRIM54 CDK5RAP2 ATM CAMSAP1 ZFY KNL1

2.92e-04421838GO:0010639
GeneOntologyBiologicalProcessplus-end-directed organelle transport along microtubule

KIF5B KIF3A

3.32e-047832GO:0072386
GeneOntologyBiologicalProcesscellular extravasation

PLVAP PIK3CD TRIM55 ADAM8

3.85e-0485834GO:0045123
GeneOntologyBiologicalProcessmeiotic nuclear division

INCENP ATM RSPO1 ZFY KNL1 FANCA

4.17e-04240836GO:0140013
GeneOntologyBiologicalProcessorganelle fission

INCENP APC CDK5RAP2 ATM SKA3 RSPO1 ZFY KNL1 FANCA

4.77e-04571839GO:0048285
GeneOntologyBiologicalProcessnegative regulation of microtubule depolymerization

APC TRIM54 CAMSAP1

4.79e-0438833GO:0007026
GeneOntologyBiologicalProcessregulation of cell cycle process

KLF11 ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM TP53BP1 ZFY KNL1

5.59e-048458311GO:0010564
GeneOntologyBiologicalProcesssister chromatid segregation

INCENP APC CDK5RAP2 ATM SKA3 KNL1

5.62e-04254836GO:0000819
GeneOntologyBiologicalProcessanterograde axonal protein transport

KIF5B KIF5C

5.65e-049832GO:0099641
GeneOntologyBiologicalProcesscell cycle process

KLF11 ATR INCENP PPP2R3B APC CDK5RAP2 PRKDC ATM SKA3 RSPO1 TP53BP1 KIF3A ZFY KNL1 FANCA

5.73e-0414418315GO:0022402
GeneOntologyBiologicalProcessmicrotubule polymerization or depolymerization

APC TRIM54 CDK5RAP2 SKA3 CAMSAP1

5.87e-04168835GO:0031109
GeneOntologyBiologicalProcessregulation of microtubule depolymerization

APC TRIM54 CAMSAP1

6.44e-0442833GO:0031114
GeneOntologyBiologicalProcessnegative regulation of G1/S transition of mitotic cell cycle

PPP2R3B APC PRKDC ATM

6.61e-0498834GO:2000134
GeneOntologyBiologicalProcessregulation of germ cell proliferation

RSPO1 FANCA

7.05e-0410832GO:1905936
GeneOntologyBiologicalProcessregulation of chromosome organization

ATR INCENP APC CDK5RAP2 ATM KNL1

7.16e-04266836GO:0033044
GeneOntologyBiologicalProcessregulation of microtubule cytoskeleton organization

APC TRIM54 CDK5RAP2 SKA3 CAMSAP1

7.25e-04176835GO:0070507
GeneOntologyBiologicalProcessmeiotic cell cycle process

INCENP ATM RSPO1 ZFY KNL1 FANCA

7.44e-04268836GO:1903046
GeneOntologyBiologicalProcessmeiotic cell cycle checkpoint signaling

ZFY KNL1

8.59e-0411832GO:0033313
GeneOntologyBiologicalProcesscellular response to X-ray

ATM TP53BP1

8.59e-0411832GO:0071481
GeneOntologyBiologicalProcessprotein localization to presynapse

KIF5B KIF5C

8.59e-0411832GO:1905383
GeneOntologyBiologicalProcessmetaphase chromosome alignment

INCENP APC SKA3 KNL1

9.18e-04107834GO:0051310
GeneOntologyBiologicalProcessnegative regulation of cell cycle G1/S phase transition

PPP2R3B APC PRKDC ATM

9.84e-04109834GO:1902807
GeneOntologyBiologicalProcessnegative regulation of microtubule polymerization or depolymerization

APC TRIM54 CAMSAP1

1.14e-0351833GO:0031111
GeneOntologyBiologicalProcessregulation of microtubule-based process

APC TRIM54 CDK5RAP2 SKA3 CAMSAP1 KIF3A

1.18e-03293836GO:0032886
GeneOntologyBiologicalProcessregulation of cell cycle checkpoint

INCENP CDK5RAP2 KNL1

1.20e-0352833GO:1901976
GeneOntologyBiologicalProcessnegative regulation of meiotic nuclear division

ZFY KNL1

1.21e-0313832GO:0045835
GeneOntologyBiologicalProcessnegative regulation of motor neuron apoptotic process

ERBB3 CNTFR

1.21e-0313832GO:2000672
GeneOntologyBiologicalProcessERBB2-ERBB3 signaling pathway

RAF1 ERBB3

1.21e-0313832GO:0038133
GeneOntologyBiologicalProcesspositive regulation of spindle checkpoint

INCENP KNL1

1.21e-0313832GO:0090232
GeneOntologyBiologicalProcessERBB3 signaling pathway

RAF1 ERBB3

1.41e-0314832GO:0038129
GeneOntologyBiologicalProcessanterograde axonal transport

KIF5B KIF5C KIF3A

1.42e-0355833GO:0008089
GeneOntologyBiologicalProcessresponse to gamma radiation

ATR PRKDC ATM

1.49e-0356833GO:0010332
GeneOntologyBiologicalProcessgerm cell proliferation

RSPO1 FANCA

1.62e-0315832GO:0036093
GeneOntologyBiologicalProcessregulation of G1/S transition of mitotic cell cycle

KLF11 PPP2R3B APC PRKDC ATM

1.69e-03213835GO:2000045
GeneOntologyBiologicalProcessmitotic nuclear division

INCENP APC CDK5RAP2 ATM SKA3 KNL1

1.73e-03316836GO:0140014
GeneOntologyCellularComponentmicrotubule

INCENP TRIM55 APC TRIM63 TRIM54 CDK5RAP2 KIF5B KIF5C SKA3 CAMSAP1 KIF3A

9.24e-065338411GO:0005874
GeneOntologyCellularComponentDNA repair complex

PRKDC ATM TP53BP1

1.05e-0423843GO:1990391
GeneOntologyCellularComponentsupramolecular fiber

FBN1 INCENP EFEMP2 NCKIPSD TRIM55 APC TRIM63 TRIM54 CDK5RAP2 KIF5B KIF5C SKA3 CAMSAP1 KIF3A

2.38e-0411798414GO:0099512
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

INCENP NCKIPSD TRIM55 APC TRIM63 TRIM54 CDK5RAP2 KIF5B KIF5C SKA3 CAMSAP1 KIF3A

2.43e-048998412GO:0099513
GeneOntologyCellularComponentsupramolecular polymer

FBN1 INCENP EFEMP2 NCKIPSD TRIM55 APC TRIM63 TRIM54 CDK5RAP2 KIF5B KIF5C SKA3 CAMSAP1 KIF3A

2.55e-0411878414GO:0099081
GeneOntologyCellularComponentchromosomal region

ATR INCENP APC PRKDC ATM SKA3 TP53BP1 KNL1

2.90e-04421848GO:0098687
GeneOntologyCellularComponentmicrotubule associated complex

INCENP TRIM54 KIF5B KIF5C KIF3A

4.82e-04161845GO:0005875
GeneOntologyCellularComponentaggresome

TRIM73 CABIN1 TRIM74

5.55e-0440843GO:0016235
GeneOntologyCellularComponentaxonal growth cone

APC KIF5B KIF5C

7.86e-0445843GO:0044295
GeneOntologyCellularComponentkinetochore

INCENP APC SKA3 TP53BP1 KNL1

8.18e-04181845GO:0000776
GeneOntologyCellularComponentcell body fiber

PENK APC

8.57e-0411842GO:0070852
GeneOntologyCellularComponentkinesin complex

KIF5B KIF5C KIF3A

1.01e-0349843GO:0005871
GeneOntologyCellularComponentcondensed chromosome, centromeric region

INCENP APC SKA3 TP53BP1 KNL1

1.09e-03193845GO:0000779
GeneOntologyCellularComponentmicrofibril

FBN1 EFEMP2

1.21e-0313842GO:0001527
GeneOntologyCellularComponentciliary rootlet

KIF5B KIF5C

1.85e-0316842GO:0035253
GeneOntologyCellularComponentextrinsic component of membrane

ATR PIK3CD APC ATM CNTFR

2.35e-03230845GO:0019898
GeneOntologyCellularComponentaxon cytoplasm

KIF5B KIF5C KIF3A

2.60e-0368843GO:1904115
HumanPhenoPrenatal growth deficiency

RAF1 KLF11 FBN1 ATR IARS1 PI4KA EFEMP2 DEF6 LEMD2 SCUBE3 PRKDC KIF5C FANCA

2.28e-056313013HP:0001515
HumanPhenoIntrauterine growth retardation

RAF1 KLF11 FBN1 ATR IARS1 PI4KA EFEMP2 DEF6 LEMD2 SCUBE3 PRKDC KIF5C FANCA

2.28e-056313013HP:0001511
MousePhenoincreased central memory CD4-positive, alpha-beta T cell number

PI4KA PRKDC ATM TP53BP1

5.36e-0624694MP:0010841
MousePhenodecreased oocyte number

ATR CDK5RAP2 ATM RSPO1 ZFX ZFY

7.13e-0695696MP:0005431
MousePhenoabnormal oocyte number

ATR CDK5RAP2 ATM RSPO1 ZFX ZFY

7.58e-0696696MP:0020152
MousePhenospontaneous chromosome breakage

ATR ATM TP53BP1 FANCA

1.18e-0529694MP:0004029
MousePhenoabnormal central memory CD4-positive, alpha-beta T cell number

PI4KA PRKDC ATM TP53BP1

1.35e-0530694MP:0012771
MousePhenoabnormal central memory CD4-positive, alpha-beta T cell morphology

PI4KA PRKDC ATM TP53BP1

1.35e-0530694MP:0010840
MousePhenodecreased mature ovarian follicle number

APC RSPO1 ZFX ZFY FANCA

2.93e-0573695MP:0002682
MousePhenoabnormal mature ovarian follicle morphology

APC RSPO1 ZFX ZFY FANCA

4.04e-0578695MP:0009364
MousePhenoabnormal oocyte morphology

ATR CDK5RAP2 ATM RSPO1 ZFX ZFY

5.97e-05138696MP:0001125
MousePhenoincreased cellular sensitivity to alkylating agents

ATR PRKDC TP53BP1

6.16e-0516693MP:0008402
MousePhenoabnormal ovarian follicle number

ATR APC ATM RSPO1 ZFX ZFY FANCA

6.18e-05203697MP:0008871
MousePhenoabnormal female germ cell morphology

ATR CDK5RAP2 ATM RSPO1 ZFX ZFY

9.49e-05150696MP:0006361
MousePhenoabnormal heart ventricle wall morphology

RAF1 FBN1 PLVAP DSC2 LEMD2 SCUBE3 TRIM63 TRIM54

1.00e-04296698MP:0031532
MousePhenoembryonic lethality during organogenesis, complete penetrance

RAF1 ERBB3 FBN1 EFEMP2 UBR4 LEMD2 APC KIF5B CABIN1 ZFX KIF3A ZFY

1.44e-047006912MP:0011098
MousePhenoabnormal CD4-positive, alpha-beta memory T cell morphology

PI4KA PRKDC ATM TP53BP1

1.53e-0455694MP:0010834
MousePhenoabnormal ovarian follicle morphology

ATR APC ATM RSPO1 ZFX ZFY FANCA

1.99e-04245697MP:0001131
MousePhenoincreased CD4-positive, alpha-beta memory T cell number

PI4KA PRKDC ATM TP53BP1

2.02e-0459694MP:0010835
MousePhenoabnormal apoptosis

RAF1 ERBB3 DSC2 ATR PI4KA UCHL3 EFEMP2 BACH1 DEF6 LEMD2 KCNMA1 APC RBM5 TRIM54 CDK5RAP2 PRKDC FANCA

2.36e-0413536917MP:0001648
MousePhenoascending aorta aneurysm

FBN1 EFEMP2

2.38e-045692MP:0010661
MousePhenochromosome breakage

ATR ATM TP53BP1 FANCA

2.44e-0462694MP:0004028
MousePhenoinduced chromosome breakage

ATR TP53BP1 FANCA

2.45e-0425693MP:0004030
MousePhenoabnormal programmed cell death

RAF1 ERBB3 DSC2 ATR PI4KA UCHL3 EFEMP2 BACH1 DEF6 LEMD2 KCNMA1 APC RBM5 TRIM54 CDK5RAP2 PRKDC FANCA

2.51e-0413606917MP:0014355
MousePhenoincreased cellular sensitivity to DNA damaging agents

ATR PRKDC TP53BP1

2.76e-0426693MP:0014040
MousePhenoincreased sensitivity to induced cell death

RAF1 ATR PRKDC ATM TP53BP1 FANCA

2.89e-04184696MP:0008943
MousePhenoabnormal oogenesis

ATR CDK5RAP2 ATM RSPO1 ZFX ZFY

3.06e-04186696MP:0001931
MousePhenodecreased splenocyte number

APC PRKDC ATM

3.45e-0428693MP:0009339
MousePhenothoracic aorta aneurysm

FBN1 EFEMP2

3.56e-046692MP:0010658
MousePhenoincreased memory T cell number

PI4KA DEF6 PRKDC ATM TP53BP1

3.62e-04124695MP:0008049
MousePhenoincreased cell death

RAF1 ERBB3 DSC2 ATR PI4KA UCHL3 LEMD2 KCNMA1 APC RBM5 TRIM54 CDK5RAP2 PRKDC FANCA

3.84e-0410196914MP:0012556
MousePhenocardiac hypertrophy

RAF1 FBN1 DSC2 TRIM55 TRIM63 TRIM54

4.05e-04196696MP:0001625
MousePhenoabnormal CD4-positive, alpha-beta memory T cell number

PI4KA PRKDC ATM TP53BP1

4.82e-0474694MP:0012769
MousePhenohypochlorhydria

TRIM73 TRIM74

4.96e-047692MP:0008001
MousePhenoabnormal female reproductive gland morphology

FBN1 ATR APC CDK5RAP2 ATM RSPO1 ZFX ZFY FANCA

5.18e-04475699MP:0013324
MousePhenoincreased gland tumor incidence

APC CDK5RAP2 PRKDC ATM TP53BP1

6.10e-04139695MP:0010288
MousePhenoabnormal cutaneous elastic fiber morphology

FBN1 EFEMP2

6.60e-048692MP:0008418
MousePhenoincreased mortality induced by gamma-irradiation

PRKDC ATM TP53BP1

7.93e-0437693MP:0001658
MousePhenoincreased aorta wall thickness

FBN1 EFEMP2

8.45e-049692MP:0010996
MousePhenoabnormal aorta bulb morphology

FBN1 EFEMP2

8.45e-049692MP:0011572
MousePhenoincreased quadriceps weight

TRIM55 TRIM63

8.45e-049692MP:0010226
DomainPI3/4_kinase_CS

ATR PIK3CD PI4KA PRKDC ATM

4.45e-0915835IPR018936
Domain-

ATR PIK3CD PI4KA PRKDC ATM

6.45e-09168351.10.1070.11
DomainPI3Kc

ATR PIK3CD PI4KA PRKDC ATM

6.45e-0916835SM00146
DomainPI3/4_kinase_cat_dom

ATR PIK3CD PI4KA PRKDC ATM

1.26e-0818835IPR000403
DomainPI3_PI4_kinase

ATR PIK3CD PI4KA PRKDC ATM

1.26e-0818835PF00454
DomainPI3_4_KINASE_3

ATR PIK3CD PI4KA PRKDC ATM

1.26e-0818835PS50290
DomainPI3_4_KINASE_1

ATR PIK3CD PI4KA PRKDC ATM

1.26e-0818835PS00915
DomainPI3_4_KINASE_2

ATR PIK3CD PI4KA PRKDC ATM

1.26e-0818835PS00916
DomainZnf-RING_LisH

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

3.86e-0734835IPR027370
Domainzf-RING_UBOX

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

3.86e-0734835PF13445
DomainFATC

ATR PRKDC ATM

8.41e-075833PF02260
DomainFAT

ATR PRKDC ATM

1.68e-066833PS51189
DomainFATC

ATR PRKDC ATM

1.68e-066833PS51190
DomainFAT

ATR PRKDC ATM

1.68e-066833PF02259
DomainPIK-rel_kinase_FAT

ATR PRKDC ATM

1.68e-066833IPR003151
DomainFATC_dom

ATR PRKDC ATM

1.68e-066833IPR003152
DomainPIK_FAT

ATR PRKDC ATM

1.68e-066833IPR014009
DomainFATC

ATR PRKDC ATM

1.68e-066833SM01343
DomainARM-type_fold

TNPO1 THADA GBF1 ATR PIK3CD PI4KA UBR4 APC PRKDC ATM

2.56e-063398310IPR016024
DomaincEGF

FBN1 EFEMP2 SCUBE3 LRP1B

5.03e-0626834IPR026823
DomaincEGF

FBN1 EFEMP2 SCUBE3 LRP1B

5.03e-0626834PF12662
DomainGrowth_fac_rcpt_

ERBB3 FBN1 EFEMP2 ELAPOR1 SCUBE3 LRP1B RSPO1

6.05e-06156837IPR009030
DomainBBOX

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

1.38e-0569835SM00336
Domain-

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

1.59e-05718354.10.45.10
Domainzf-B_box

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

1.70e-0572835PF00643
DomainCOS_domain

TRIM55 TRIM63 TRIM54

1.81e-0512833IPR017903
DomainCOS

TRIM55 TRIM63 TRIM54

1.81e-0512833PS51262
DomainZF_BBOX

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

2.84e-0580835PS50119
DomainZnf_B-box

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

3.02e-0581835IPR000315
DomainZfx_Zfy_act

ZFX ZFY

5.84e-053832PF04704
DomainTranscrp_activ_Zfx/Zfy-dom

ZFX ZFY

5.84e-053832IPR006794
DomainZF_UBR

UBR4 UBR3

4.04e-047832PS51157
Domainzf-UBR

UBR4 UBR3

4.04e-047832PF02207
DomainZnf_UBR

UBR4 UBR3

4.04e-047832IPR003126
DomainZnF_UBR1

UBR4 UBR3

4.04e-047832SM00396
Domainzf-C3HC4

TRIM73 TRIM55 TRIM63 TRIM54 UBR3 TRIM74

4.76e-04223836PF00097
DomainEGF_CA

FBN1 EFEMP2 SCUBE3 LRP1B

5.84e-0486834PF07645
DomainPI3Ka

PIK3CD PI4KA

6.88e-049832PF00613
Domain-

PIK3CD PI4KA

6.88e-0498321.25.40.70
DomainPI3Ka

PIK3CD PI4KA

6.88e-049832SM00145
DomainKinesin_motor_CS

KIF5B KIF5C KIF3A

7.99e-0441833IPR019821
DomainZnf_RING_CS

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

7.99e-04163835IPR017907
Domain-

SP140L TRIM73 KDM5C TRIM55 TRIM63 TRIM54 UBR3 TRIM74

8.55e-044498383.30.40.10
DomainPIK_HELICAL

PIK3CD PI4KA

8.58e-0410832PS51545
DomainPI_Kinase

PIK3CD PI4KA

8.58e-0410832IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3CD PI4KA

8.58e-0410832IPR001263
DomainEGF_Ca-bd_CS

FBN1 EFEMP2 SCUBE3 LRP1B

9.18e-0497834IPR018097
DomainKinesin-like_fam

KIF5B KIF5C KIF3A

9.19e-0443833IPR027640
DomainKINESIN_MOTOR_1

KIF5B KIF5C KIF3A

9.83e-0444833PS00411
Domain-

KIF5B KIF5C KIF3A

9.83e-04448333.40.850.10
DomainKinesin_motor_dom

KIF5B KIF5C KIF3A

9.83e-0444833IPR001752
DomainKinesin

KIF5B KIF5C KIF3A

9.83e-0444833PF00225
DomainKINESIN_MOTOR_2

KIF5B KIF5C KIF3A

9.83e-0444833PS50067
DomainKISc

KIF5B KIF5C KIF3A

9.83e-0444833SM00129
DomainZnf_RING/FYVE/PHD

SP140L TRIM73 KDM5C TRIM55 TRIM63 TRIM54 UBR3 TRIM74

9.86e-04459838IPR013083
DomainEGF_CA

FBN1 EFEMP2 SCUBE3 LRP1B

9.91e-0499834PS01187
DomainZnf_C3HC4_RING-type

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

1.02e-03172835IPR018957
DomainASX_HYDROXYL

FBN1 EFEMP2 SCUBE3 LRP1B

1.03e-03100834PS00010
DomainHEAT

TNPO1 ATR PRKDC

1.27e-0348833PF02985
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 EFEMP2 SCUBE3 LRP1B

1.28e-03106834IPR000152
DomainZF_RING_1

TRIM73 TRIM55 TRIM63 TRIM54 UBR3 TRIM74

1.88e-03291836PS00518
DomainZF_RING_2

TRIM73 TRIM55 TRIM63 TRIM54 UBR3 TRIM74

2.12e-03298836PS50089
DomainEGF_CA

FBN1 EFEMP2 SCUBE3 LRP1B

2.14e-03122834SM00179
DomainHEAT

TNPO1 ATR PRKDC

2.19e-0358833IPR000357
DomainEGF-like_Ca-bd_dom

FBN1 EFEMP2 SCUBE3 LRP1B

2.27e-03124834IPR001881
DomainKinase-like_dom

RAF1 ERBB3 ATR PIK3CD PI4KA PRKDC ATM CAMK1

2.80e-03542838IPR011009
DomainFurin_repeat

ERBB3 RSPO1

2.85e-0318832IPR006212
DomainFU

ERBB3 RSPO1

2.85e-0318832SM00261
DomainZnf_RING

TRIM73 TRIM55 TRIM63 TRIM54 UBR3 TRIM74

3.30e-03326836IPR001841
DomainHEAT_REPEAT

TNPO1 ATR PRKDC

3.74e-0370833PS50077
DomainEGF_3

FBN1 EFEMP2 SCUBE3 ADAM8 LRP1B

3.96e-03235835PS50026
DomainEGF

FBN1 EFEMP2 SCUBE3 ADAM8 LRP1B

3.96e-03235835SM00181
PathwayPID_BARD1_PATHWAY

ATR PRKDC ATM FANCA

1.21e-0529704M258
PathwayWP_DNA_IRDAMAGE_AND_CELLULAR_RESPONSE_VIA_ATR

ATR PRKDC ATM TP53BP1 FANCA

4.99e-0581705M39490
PathwayWP_ATM_SIGNALING_IN_DEVELOPMENT_AND_DISEASE

ATR PRKDC ATM TP53BP1

8.46e-0547704M39518
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

RAF1 DPPA4 PIK3CD KDM5C APC CABIN1 ZFX ZFY

1.18e-04301708MM15983
PathwayWP_DNA_IRDOUBLE_STRAND_BREAKS_AND_CELLULAR_RESPONSE_VIA_ATM

ATR PRKDC ATM TP53BP1

1.57e-0455704M39598
PathwayBIOCARTA_ATRBRCA_PATHWAY

ATR ATM FANCA

1.69e-0422703M9703
PathwayBIOCARTA_G2_PATHWAY

ATR PRKDC ATM

2.20e-0424703M8560
Pubmed

Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.

ATR PRKDC ATM

1.41e-0838539766667
Pubmed

Tagging single nucleotide polymorphisms in phosphoinositide-3-kinase-related protein kinase genes involved in DNA damage "checkpoints" and lung cancer susceptibility.

ATR PRKDC ATM

1.41e-08385318451257
Pubmed

DNA Damage Signaling Is Required for Replication of Human Bocavirus 1 DNA in Dividing HEK293 Cells.

ATR PRKDC ATM

1.41e-08385327733644
Pubmed

DNA-PKcs and ATM epistatically suppress DNA end resection and hyperactivation of ATR-dependent G2-checkpoint in S-phase irradiated cells.

ATR PRKDC ATM

1.41e-08385331601897
Pubmed

Radiation-dose-dependent functional synergisms between ATM, ATR and DNA-PKcs in checkpoint control and resection in G2-phase.

ATR PRKDC ATM

1.41e-08385331164689
Pubmed

Distinct roles of ATR and DNA-PKcs in triggering DNA damage responses in ATM-deficient cells.

ATR PRKDC ATM

1.41e-08385319444312
Pubmed

SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.

ATR PRKDC ATM

5.63e-08485315998665
Pubmed

ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation.

ATR ATM TP53BP1

5.63e-08485315539948
Pubmed

Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.

PRKDC ATM TP53BP1

5.63e-08485319450527
Pubmed

Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.

TRIM55 TRIM63 TRIM54

5.63e-08485311243782
Pubmed

Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.

ATR PRKDC ATM

1.40e-07585319596237
Pubmed

Phosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation.

ATR PRKDC ATM

1.40e-07585316540648
Pubmed

ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.

PRKDC ATM TP53BP1

1.40e-07585317599403
Pubmed

Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.

PRKDC ATM TP53BP1

1.40e-07585320231360
Pubmed

53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.

PRKDC ATM TP53BP1

1.40e-07585325264618
Pubmed

ATR is a multifunctional regulator of male mouse meiosis.

ATR PRKDC ATM

1.40e-07585329976923
Pubmed

The complexity of p53 modulation: emerging patterns from divergent signals.

ATR PRKDC ATM

2.80e-0768539765199
Pubmed

E3-ligase knock down revealed differential titin degradation by autopagy and the ubiquitin proteasome system.

TRIM55 TRIM63 TRIM54

2.80e-07685334702928
Pubmed

Telomere protection by TPP1/POT1 requires tethering to TIN2.

ATR PRKDC ATM

4.90e-07785322099311
Pubmed

Centrosomal localization of DNA damage checkpoint proteins.

ATR PRKDC ATM

4.90e-07785317171639
Pubmed

Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1.

TRIM55 TRIM63 TRIM54

4.90e-07785311927605
Pubmed

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer.

ATR ATM TP53BP1

4.90e-07785316872911
Pubmed

The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.

ATR PRKDC ATM

4.90e-07785310673501
Pubmed

Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.

TNPO1 IARS1 UBR4 PRKDC

6.50e-072885435227662
Pubmed

Gene knockouts that cause female infertility: search for novel contraceptive targets.

ATM ZFX ZFY FANCA

6.50e-072885415970507
Pubmed

Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.

ATR PRKDC ATM

7.82e-07885315456891
Pubmed

Vpr-binding protein antagonizes p53-mediated transcription via direct interaction with H3 tail.

ATR PRKDC ATM

7.82e-07885322184063
Pubmed

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.

ATR PRKDC ATM

7.82e-07885320810650
Pubmed

Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.

ATR ATM TP53BP1 FANCA

9.94e-073185419690177
Pubmed

Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.

TRIM55 TRIM63 TRIM54

1.17e-06985321185285
Pubmed

Tel2 regulates the stability of PI3K-related protein kinases.

ATR PRKDC ATM

1.67e-061085318160036
Pubmed

A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate.

UCHL3 TRIM55 TRIM63 TRIM54

1.84e-063685422626734
Pubmed

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.

ATR PRKDC ATM

2.29e-061185320427287
Pubmed

Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.

ATR PRKDC ATM

2.29e-061185315758953
Pubmed

Plk3 functionally links DNA damage to cell cycle arrest and apoptosis at least in part via the p53 pathway.

ATR PRKDC ATM

2.29e-061185311551930
Pubmed

UV-radiation induces dose-dependent regulation of p53 response and modulates p53-HDM2 interaction in human fibroblasts.

ATR PRKDC ATM

2.29e-061185311709713
Pubmed

Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.

PRKDC ATM TP53BP1

2.29e-061185316400328
Pubmed

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.

ATR ATM TP53BP1

2.29e-061185315364958
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ERBB3 ZBTB38 FBN1 EFEMP2 UBR4 BACH1 APC PRKDC ATM CAMK1 KIF5C CABIN1 LRP1B KIF3A

2.70e-061285851435914814
Pubmed

Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.

ATR BACH1 PRKDC ATM FANCA

2.73e-068985518950845
Pubmed

Rheb binds and regulates the mTOR kinase.

RAF1 ATR ATM

3.05e-061285315854902
Pubmed

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).

ATR ATM TP53BP1

3.05e-061285315149599
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

LRCH2 PI4KA UBR4 KCNMA1 APC CDK5RAP2 KIF5B KIF5C CAMSAP1 CABIN1 TP53BP1 KIF3A

3.90e-06963851228671696
Pubmed

Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.

ERBB3 ATR PIK3CD HMGCR PRKDC ATM CNTFR

5.35e-0627685728319085
Pubmed

Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks.

ATR ATM

5.90e-06285219285939
Pubmed

Expression variations of DNA damage response genes ATM and ATR in blood cancer patients.

ATR ATM

5.90e-06285237338595
Pubmed

53BP1 depletion causes PARP inhibitor resistance in ATM-deficient breast cancer cells.

ATM TP53BP1

5.90e-06285227613518
Pubmed

ATM and 53BP1 regulate alternative end joining-mediated V(D)J recombination.

ATM TP53BP1

5.90e-06285239083600
Pubmed

Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis.

PRKDC ATM

5.90e-06285211231155
Pubmed

DNA damage induces a kinetochore-based ATM/ATR-independent SAC arrest unique to the first meiotic division in mouse oocytes.

ATR ATM

5.90e-06285228851706
Pubmed

Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation.

PRKDC ATM

5.90e-06285210464290
Pubmed

Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.

PRKDC ATM

5.90e-06285227939942
Pubmed

Novel insights into the mechanism of cell cycle kinases Mec1(ATR) and Tel1(ATM).

ATR ATM

5.90e-06285234151669
Pubmed

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.

ZFX ZFY

5.90e-0628521691708
Pubmed

The structure of the Zfx gene on the mouse X chromosome.

ZFX ZFY

5.90e-0628528188262
Pubmed

The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.

PRKDC ATM

5.90e-06285221487018
Pubmed

DNA structure-specific priming of ATR activation by DNA-PKcs.

ATR PRKDC

5.90e-06285223897887
Pubmed

Inhibition of Atm and/or Atr disrupts gene silencing on the inactive X chromosome.

ATR ATM

5.90e-06285216213462
Pubmed

Mapping the human ZFX locus to Xp21.3 by in situ hybridization.

ZFX ZFY

5.90e-0628522497060
Pubmed

ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.

ATR ATM

5.90e-06285227442013
Pubmed

Activation of DNA Damage Response Pathways during Lytic Replication of KSHV.

PRKDC ATM

5.90e-06285226057167
Pubmed

Induction of ATM/ATR pathway combined with Vγ2Vδ2 T cells enhances cytotoxicity of ovarian cancer cells.

ATR ATM

5.90e-06285224726882
Pubmed

Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.

ZFX ZFY

5.90e-0628522041734
Pubmed

Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.

ZFX ZFY

5.90e-0628528318216
Pubmed

rRNA synthesis inhibitor, CX-5461, activates ATM/ATR pathway in acute lymphoblastic leukemia, arrests cells in G2 phase and induces apoptosis.

ATR ATM

5.90e-06285226061708
Pubmed

53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.

ATM TP53BP1

5.90e-06285223858098
Pubmed

[Expression of Zfx in mouse testicular spermatogenic cells].

ZFX ZFY

5.90e-06285238602753
Pubmed

Functional significance for a heterogenous ribonucleoprotein A18 signature RNA motif in the 3'-untranslated region of ataxia telangiectasia mutated and Rad3-related (ATR) transcript.

ATR ATM

5.90e-06285220103595
Pubmed

Interplay between ATM and ATR in the regulation of common fragile site stability.

ATR ATM

5.90e-06285217934520
Pubmed

Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.

ATR ATM

5.90e-06285225483091
Pubmed

ATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.

ATR ATM

5.90e-06285223592994
Pubmed

Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway.

ATR ATM

5.90e-06285219527713
Pubmed

Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.

ZFX ZFY

5.90e-06285212716983
Pubmed

Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.

ZFX ZFY

5.90e-0628529126493
Pubmed

Phosphorylation of the DNA damage repair factor 53BP1 by ATM kinase controls neurodevelopmental programs in cortical brain organoids.

ATM TP53BP1

5.90e-06285239226322
Pubmed

DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.

PRKDC ATM

5.90e-06285219071136
Pubmed

Roles of DNA-dependent protein kinase and ATM in cell-cycle-dependent radiation sensitivity in human cells.

PRKDC ATM

5.90e-06285212065055
Pubmed

Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.

ZFX ZFY

5.90e-0628528487630
Pubmed

ATM and ATR signaling at a glance.

ATR ATM

5.90e-06285226567218
Pubmed

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

PRKDC ATM

5.90e-06285217189255
Pubmed

AIF-mediated caspase-independent necroptosis requires ATM and DNA-PK-induced histone H2AX Ser139 phosphorylation.

PRKDC ATM

5.90e-06285222972376
Pubmed

G(2)-M phase-correlative bystander effects are co-mediated by DNA-PKcs and ATM after carbon ion irradiation.

PRKDC ATM

5.90e-06285226774662
Pubmed

Cancer genome datamining and functional genetic analysis implicate mechanisms of ATM/ATR dysfunction underpinning carcinogenesis.

ATR ATM

5.90e-06285233742106
Pubmed

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

ATM TP53BP1

5.90e-06285211042216
Pubmed

Roles of ATM and ATR in DNA double strand breaks and replication stress.

ATR ATM

5.90e-06285233887296
Pubmed

ATR disruption leads to chromosomal fragmentation and early embryonic lethality.

ATR ATM

5.90e-06285210691732
Pubmed

The phosphatidylinositol 4-kinase PI4KIIIalpha is required for the recruitment of GBF1 to Golgi membranes.

GBF1 PI4KA

5.90e-06285220530568
Pubmed

Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis.

ATM FANCA

5.90e-06285218224251
Pubmed

Zfx mutation results in small animal size and reduced germ cell number in male and female mice.

ZFX ZFY

5.90e-0628529187153
Pubmed

Hypoosmotic stress induces R loop formation in nucleoli and ATR/ATM-dependent silencing of nucleolar transcription.

ATR ATM

5.90e-06285231114877
Pubmed

S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response.

ATM TP53BP1

5.90e-06285218996087
Pubmed

Shift in G1-Checkpoint from ATM-Alone to a Cooperative ATM Plus ATR Regulation with Increasing Dose of Radiation.

ATR ATM

5.90e-06285235011623
Pubmed

The orally active and bioavailable ATR kinase inhibitor AZD6738 potentiates the anti-tumor effects of cisplatin to resolve ATM-deficient non-small cell lung cancer in vivo.

ATR ATM

5.90e-06285226517239
Pubmed

Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.

ZFX ZFY

5.90e-0628522265557
Pubmed

DNA damage-sensing kinases mediate the mouse 2-cell embryo's response to genotoxic stress.

ATR ATM

5.90e-06285221593482
Pubmed

A synthetic lethal screen reveals enhanced sensitivity to ATR inhibitor treatment in mantle cell lymphoma with ATM loss-of-function.

ATR ATM

5.90e-06285225232030
Pubmed

DNA-PKcs and ATM modulate mitochondrial ADP-ATP exchange as an oxidative stress checkpoint mechanism.

PRKDC ATM

5.90e-06285236727301
Pubmed

Development of the tight-skin phenotype in immune-deficient mice.

FBN1 PRKDC

5.90e-06285211263788
Pubmed

Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation.

APC PRKDC

5.90e-0628528567125
Pubmed

ATM acts downstream of ATR in the DNA damage response signaling of bystander cells.

ATR ATM

5.90e-06285218757420
InteractionP2RY10 interactions

THADA GBF1 PI4KA PRKDC ATM CAMK1 FANCA

2.73e-07106837int:P2RY10
InteractionZNF667-AS1 interactions

TRIM55 TRIM63 TRIM54

6.70e-075833int:ZNF667-AS1
InteractionFAM234A interactions

TNPO1 THADA GBF1 ATR PRKDC ATM PLXNA2

8.84e-07126837int:FAM234A
InteractionZNF345 interactions

EFEMP2 TRIM55 TRIM63

2.33e-067833int:ZNF345
InteractionGPR17 interactions

THADA GBF1 ATR UBR3 HMGCR PRKDC ATM CAMK1 FANCA

2.48e-06283839int:GPR17
InteractionFPR1 interactions

THADA GBF1 PI4KA PRKDC ATM CAMK1 FANCA

2.49e-06147837int:FPR1
InteractionNPY2R interactions

GBF1 PI4KA PRKDC ATM FANCA

7.70e-0666835int:NPY2R
InteractionSPSB1 interactions

ATR TRIM55 TRIM63 ATM

9.99e-0633834int:SPSB1
InteractionATXN3L interactions

TRIM55 TRIM63 TRIM54

1.09e-0511833int:ATXN3L
InteractionPLA2G2A interactions

RAF1 ERBB3 UCHL3 APC

1.77e-0538834int:PLA2G2A
InteractionC8orf74 interactions

TRIM55 TRIM63 TRIM54

1.87e-0513833int:C8orf74
InteractionPLA2G4C interactions

ATR HMGCR PRKDC

1.87e-0513833int:PLA2G4C
InteractionMRE11 interactions

RAF1 GBF1 ATR KIF5B PRKDC ATM SKA3 TP53BP1

2.40e-05287838int:MRE11
InteractionDCLRE1C interactions

ATR PRKDC ATM TP53BP1

2.92e-0543834int:DCLRE1C
InteractionELAPOR1 interactions

ELAPOR1 TRIM55 TRIM63

3.63e-0516833int:ELAPOR1
InteractionLIG4 interactions

ATR RBM5 PRKDC ATM TP53BP1 KIF3A

3.90e-05152836int:LIG4
InteractionZNF57 interactions

EFEMP2 TRIM55 TRIM63

4.39e-0517833int:ZNF57
InteractionLINC00905 interactions

TRIM55 TRIM63

5.01e-053832int:LINC00905
InteractionKIF5A interactions

BACH1 TRIM55 TRIM63 KIF5B KIF5C

5.28e-0598835int:KIF5A
InteractionITGB3 interactions

RAF1 IARS1 UBR4 KIF5B PRKDC TP53BP1

7.28e-05170836int:ITGB3
InteractionSPN interactions

THADA GBF1 ATR PI4KA

8.95e-0557834int:SPN
InteractionP2RY8 interactions

THADA GBF1 PI4KA HMGCR ATM FANCA

9.67e-05179836int:P2RY8
InteractionLINC01588 interactions

KDM5C TRIM55 TRIM63

9.80e-0522833int:LINC01588
InteractionLINC00518 interactions

TRIM55 TRIM63

1.00e-044832int:LINC00518
InteractionLYNX1 interactions

TRIM55 TRIM63

1.00e-044832int:LYNX1
InteractionAPOBEC4 interactions

TRIM55 TRIM63

1.00e-044832int:APOBEC4
InteractionGOLGA2P5 interactions

TRIM55 TRIM63

1.00e-044832int:GOLGA2P5
InteractionUSP28 interactions

UCHL3 TRIM55 TRIM63 ATM TP53BP1

1.04e-04113835int:USP28
InteractionAZIN1 interactions

KIF5B KIF5C FANCA

1.12e-0423833int:AZIN1
InteractionC3orf18 interactions

THADA ATR PI4KA HMGCR PRKDC

1.13e-04115835int:C3orf18
InteractionUCHL3 interactions

UCHL3 TRIM55 TRIM63 TRIM54 PRKDC ATM

1.16e-04185836int:UCHL3
InteractionRANBP2 interactions

TNPO1 GBF1 TRIM55 APC KIF5B PRKDC KIF5C KIF3A

1.20e-04361838int:RANBP2
InteractionNTN5 interactions

FBN1 APC LRP1B

1.28e-0424833int:NTN5
InteractionLMCD1 interactions

RAF1 TRIM55 TRIM63

1.28e-0424833int:LMCD1
InteractionMSH5 interactions

GLG1 TRIM54 FANCA

1.45e-0425833int:MSH5
InteractionDRD4 interactions

PRKDC ATM ADCY2

1.45e-0425833int:DRD4
InteractionNPTN interactions

TNPO1 THADA GBF1 ATR PI4KA ATM FANCA

1.50e-04278837int:NPTN
InteractionCOPS5 interactions

TNPO1 RAF1 LRCH2 IARS1 UCHL3 UBR4 NCKIPSD APC RBM5 KIF5B PRKDC ATM SKA3 TP53BP1

1.51e-0411028314int:COPS5
InteractionHDAC1 interactions

SFMBT1 RAF1 KLF11 ATR KDM5C UBR4 BACH1 APC CDK5RAP2 ATM SKA3 CAMSAP1 CABIN1 KNL1

1.60e-0411088314int:HDAC1
InteractionLINC00663 interactions

TRIM55 TRIM63

1.66e-045832int:LINC00663
InteractionSLC6A13 interactions

TRIM55 TRIM63

1.66e-045832int:SLC6A13
InteractionKIAA0087 interactions

TRIM55 TRIM63

1.66e-045832int:KIAA0087
InteractionGPR55 interactions

GBF1 ATR PI4KA FANCA

1.68e-0467834int:GPR55
InteractionCSNK1A1 interactions

TNPO1 RAF1 BACH1 NCKIPSD APC PRKDC ATM SKA3

1.74e-04381838int:CSNK1A1
InteractionCA14 interactions

TNPO1 THADA ATR PI4KA

2.11e-0471834int:CA14
InteractionBRCC3 interactions

RAF1 BACH1 DEF6 TP53BP1 FANCA

2.15e-04132835int:BRCC3
InteractionOPALIN interactions

RAF1 THADA ATR PI4KA PRKDC ATM

2.25e-04209836int:OPALIN
InteractionFHL2 interactions

TRIM73 TRIM55 APC RBM5 TRIM63 KIF5B ZNF85 KNL1

2.26e-04396838int:FHL2
InteractionMN1 interactions

TNPO1 PRKDC ZBTB24

2.28e-0429833int:MN1
InteractionHDAC4 interactions

PI4KA EFEMP2 UBR4 KCNMA1 APC KIF5B ATM CAMK1 TP53BP1 ZFX KIF3A

2.31e-047448311int:HDAC4
InteractionEGLN3 interactions

TNPO1 RAF1 GBF1 LRCH2 PI4KA UBR4 BACH1 APC CDK5RAP2 PRR14L KIF5B PRKDC SKA3 CAMSAP1 KNL1

2.37e-0412968315int:EGLN3
InteractionGPR45 interactions

TNPO1 THADA GBF1 ATR PI4KA ATM FANCA

2.39e-04300837int:GPR45
InteractionDYNLL1 interactions

SFMBT1 RAF1 IARS1 BACH1 NCKIPSD TRIM54 CDK5RAP2 ATM TP53BP1

2.48e-04510839int:DYNLL1
InteractionMRPL20-AS1 interactions

TRIM55 TRIM63

2.49e-046832int:MRPL20-AS1
InteractionRUSC1-AS1 interactions

TRIM55 TRIM63

2.49e-046832int:RUSC1-AS1
InteractionCYP46A1 interactions

TRIM55 TRIM63

2.49e-046832int:CYP46A1
InteractionUSP5 interactions

KDM5C UCHL3 TRIM55 TRIM63 TRIM54 PRKDC

2.49e-04213836int:USP5
InteractionBUB1 interactions

NANS APC CDK5RAP2 TP53BP1 KNL1

2.56e-04137835int:BUB1
InteractionYWHAZ interactions

RAF1 KLF11 ERBB3 GBF1 DSC2 NCKIPSD KCNMA1 APC CDK5RAP2 PRR14L KIF5B ATM KIF5C CAMSAP1 TP53BP1

2.87e-0413198315int:YWHAZ
InteractionUPP1 interactions

RAF1 UBR4 PRR14L TP53BP1

3.03e-0478834int:UPP1
InteractionVSIG2 interactions

TNPO1 THADA ATR

3.07e-0432833int:VSIG2
InteractionCD80 interactions

THADA ATR PRKDC ATM

3.18e-0479834int:CD80
InteractionOPRM1 interactions

THADA ATR PI4KA ATM FANCA

3.22e-04144835int:OPRM1
InteractionFAM174A interactions

TNPO1 RAF1 THADA GBF1 ATR PI4KA

3.26e-04224836int:FAM174A
InteractionPRR30 interactions

TRIM55 TRIM63

3.47e-047832int:PRR30
InteractionIL18RAP interactions

TRIM54 IL18RAP

3.47e-047832int:IL18RAP
InteractionFMR1 interactions

RAF1 LRCH2 UBR4 KCNMA1 APC CDK5RAP2 KIF5B KIF5C TP53BP1

3.57e-04536839int:FMR1
InteractionPOU6F2 interactions

THADA TRIM73 KIF5B ZBTB24 TP53BP1

3.66e-04148835int:POU6F2
InteractionNDP interactions

KDM5C LRP1B PLXNA2

4.01e-0435833int:NDP
InteractionPHC2 interactions

SFMBT1 RAF1 TRIM55 TRIM63 ZBTB24

4.26e-04153835int:PHC2
InteractionAP1B1 interactions

RAF1 ATR IARS1 PRKDC ATM CABIN1

4.40e-04237836int:AP1B1
InteractionHLA-B interactions

ERBB3 GBF1 ATR PI4KA PRKDC FANCA

4.60e-04239836int:HLA-B
InteractionSLFN12 interactions

TRIM55 TRIM63

4.62e-048832int:SLFN12
InteractionERAS interactions

RAF1 PIK3CD

4.62e-048832int:ERAS
InteractionOGFOD2 interactions

TRIM55 TRIM63

4.62e-048832int:OGFOD2
InteractionNSUN7 interactions

TRIM55 TRIM63

4.62e-048832int:NSUN7
InteractionCENPK interactions

KDM5C TRIM55 TRIM63 SKA3

4.79e-0488834int:CENPK
InteractionSASS6 interactions

DPPA4 UBR4 APC CDK5RAP2 ENTHD1

5.08e-04159835int:SASS6
InteractionCREM interactions

TNPO1 IARS1 UBR4 PRKDC

5.22e-0490834int:CREM
InteractionPELO interactions

ZBTB38 TRIM55 TRIM63 SKA3 TP53BP1

5.37e-04161835int:PELO
InteractionBRCA1 interactions

TNPO1 GBF1 ATR IARS1 UBR4 XAF1 KIF5B PRKDC ATM CABIN1 TP53BP1 TRIM74 KNL1 FANCA

5.43e-0412498314int:BRCA1
InteractionYWHAH interactions

RAF1 GBF1 LRCH2 DSC2 TFB1M PI4KA NCKIPSD KCNMA1 APC KIF5B KIF5C SKA3 CAMSAP1

5.43e-0411028313int:YWHAH
InteractionRHEB interactions

RAF1 ATR TRIM55 TRIM63 ATM

5.84e-04164835int:RHEB
InteractionAPLN interactions

TRIM55 TRIM63

5.92e-049832int:APLN
InteractionDAPL1 interactions

TRIM55 TRIM63

5.92e-049832int:DAPL1
InteractionMAGEC3 interactions

TRIM55 TRIM63

5.92e-049832int:MAGEC3
InteractionCHRM4 interactions

THADA GBF1 PRKDC FANCA

6.15e-0494834int:CHRM4
InteractionFXYD3 interactions

TNPO1 THADA GBF1 ATR

6.15e-0494834int:FXYD3
InteractionDOCK7 interactions

RAF1 ERBB3 LRCH2 NCKIPSD TRIM55 TRIM63

6.34e-04254836int:DOCK7
InteractionNOSIP interactions

TNPO1 RAF1 ATR TP53BP1

6.40e-0495834int:NOSIP
InteractionATRIP interactions

ATR PRKDC ATM TP53BP1

6.40e-0495834int:ATRIP
InteractionINSYN1 interactions

UBR4 CDK5RAP2 KIF5B KIF5C KIF3A

6.70e-04169835int:INSYN1
InteractionSHFL interactions

RAF1 TRIM55 TRIM63 UBR3

6.93e-0497834int:SHFL
InteractionKCNMB1 interactions

KCNMA1 TRIM63

7.38e-0410832int:KCNMB1
InteractionGYPA interactions

TNPO1 THADA GBF1 ATR CAMK1

7.64e-04174835int:GYPA
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

1.22e-059557559
GeneFamilyUbiquitin protein ligase E3 component n-recognins

UBR4 UBR3

2.03e-047572785
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF5B KIF5C KIF3A

4.10e-0446573622
GeneFamilyRing finger proteins

TRIM73 TRIM55 TRIM63 TRIM54 TRIM74

1.72e-0327557558
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

TNPO1 ZBTB38 ATR IARS1 PENK APC TRIM63 CDK5RAP2 KIF5B ZNF85 ATM KIF3A KNL1

1.90e-076568513M18979
CoexpressionPUJANA_BREAST_CANCER_LIT_INT_NETWORK

ATR BACH1 PRKDC ATM TP53BP1 FANCA

9.63e-07101856M15356
CoexpressionVALK_AML_CLUSTER_6

DSC2 DPPA4 ADCY2 TP53BP1

4.43e-0634854M4965
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

ZBTB38 ATR SP140L IARS1 KCNMA1 APC XAF1 KIF5B SKA3 CAMSAP1 KNL1

2.12e-057218511M10237
CoexpressionGSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_DN

DSC2 EFEMP2 PENK KIF5C CAMSAP1 KIF3A

4.85e-05200856M5153
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

INCENP ELAPOR1 ZNF85 SKA3 KNL1 FANCA

1.08e-06175856f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

INCENP ELAPOR1 CDK5RAP2 SKA3 KNL1 FANCA

1.49e-0618585630e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

INCENP ELAPOR1 CDK5RAP2 SKA3 KNL1 FANCA

1.58e-061878569351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|COVID-19 / Disease (COVID-19 only), tissue and cell type

TRIM63 TRIM54 UNC13C ADCY2 CNTFR

8.36e-06144855f92e03dd784e31a9e5dbd4f4c3a6517ea19210cf
ToppCell368C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANO9 PLVAP ELAPOR1 FAM227A ZNF85

1.16e-05154855f29316d4b4dcdb23bd427d78068e65a9802f7f07
ToppCell368C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ANO9 PLVAP ELAPOR1 FAM227A ZNF85

1.16e-0515485566065c0763c83d98084ca6969694c3af37e43274
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP INCENP XAF1 RSPO1 FANCA

1.19e-05155855969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellfacs-Heart-RV-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PENK TRIM63 MYO15A HS6ST3 CFAP46

1.31e-051588552ef43d14ee65d004dc62c12ff209bbe12e4db681
ToppCellClub_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

ERBB3 FBN1 ELAPOR1 SCUBE3 KIF5C

1.35e-05159855a7bcff268b1962a561fd2848e01ae16565bce895
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBN1 INCENP CDK5RAP2 SKA3 KNL1

1.97e-05172855c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 PENK RSPO1 ADCY2 CNTFR

2.45e-05180855c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 PENK RSPO1 ADCY2 CNTFR

2.45e-0518085532c6a3886428d82fb4355d987c6d2645f333447b
ToppCellwk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ERBB3 TFB1M UNC13C KIF5C PLXNA2

2.80e-05185855636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GALNTL6 PENK HS6ST3 LRP1B CNTFR

2.87e-051868558915436d09775f2828a7678af203b1082b36e21c
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

THADA GBF1 GLG1 BACH1 ZNF740

2.95e-05187855689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 INCENP SKA3 KNL1 FANCA

2.95e-05187855e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 INCENP SKA3 KNL1 FANCA

2.95e-05187855cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

INCENP UNC13C SKA3 KNL1 FANCA

2.95e-05187855057569c9437219ecc396aa6e673b1178a2273837
ToppCellFibroblast-E_(Early_Fibroblastic_progenitor)|World / shred on cell class and cell subclass (v4)

FBN1 INCENP SKA3 KNL1 FANCA

3.02e-05188855be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCellfacs-Heart-RA-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM5 DSC2 PENK TRIM63 CNTFR

3.10e-05189855e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GSTM5 FBN1 COL21A1 EFEMP2 RSPO1

3.10e-051898554f9608b84d135268a17455661870c46ae8554a24
ToppCelldroplet-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP2 PENK RSPO1 ADCY2

3.18e-051908552abeb013bb83c578e67dcb985ba44ca63134950b
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

INCENP CDK5RAP2 SKA3 KNL1 FANCA

3.18e-05190855d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GBF1 TRIM73 GLG1 HMGCR PRKDC

3.26e-051918559454f642c3621370fa23640b631301346b300950
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 EFEMP2 PENK RSPO1 ADCY2

3.26e-05191855d1205aab0937f2becfcd239610e9b78fb8a0c886
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

COL21A1 TRIM73 FAM227A PLXNA2 CFAP46

3.42e-05193855ea345d34440b25f65358a53dc72831998d1c3620
ToppCellCOVID-19-lung-NK_cells|COVID-19 / Disease (COVID-19 only), tissue and cell type

PIK3CD DEF6 ATM ADAM8 IL18RAP

3.51e-051948554c92f18e0a34fb50630d4b260eaf179202508b6d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GSTM5 FBN1 PENK RSPO1 CNTFR

3.51e-0519485502b8102be9414d6964cd71019613edff6d88b893
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP INCENP CDK5RAP2 SKA3 KNL1

3.60e-051958555790b47b0e028e49b99bda8d6d9e80ac79208cdf
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP INCENP CDK5RAP2 SKA3 KNL1

3.69e-0519685520383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellBronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DPPA4 PIK3CD TRIM54 UNC13C IL18RAP

3.69e-051968551cc2b11764584129703ec61965e8ec4e051464e7
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLVAP INCENP CDK5RAP2 SKA3 KNL1

3.69e-051968550644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL21A1 KCNMA1 HS6ST3 LRP1B ADCY2

3.69e-051968559830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellwk_20-22-Mesenchymal-Fibroblast-Airway_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GSTM5 FBN1 COL21A1 EFEMP2 RSPO1

3.78e-05197855233caeee200ca905900226f85426e084caf290fb
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRSS54 PENK ELAPOR1 KIF5C ADCY2

3.87e-051988556712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FBN1 COL21A1 EFEMP2 HMGCR CNTFR

3.96e-0519985538ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRSS54 PENK ELAPOR1 KIF5C ADCY2

3.96e-0519985560919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GSTM5 FBN1 COL21A1 EFEMP2 CNTFR

3.96e-0519985508bdcabc3fce787578a8eb66fc8412b0974fa6cc
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRSS54 PENK ELAPOR1 KIF5C ADCY2

3.96e-051998556aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell11.5-Airway|11.5 / Age, Tissue, Lineage and Cell class

ERBB3 PENK ELAPOR1 SCUBE3 ADCY2

4.06e-052008559e3a8978b76ee9ba1ccc220f128dad081eceba1a
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PENK ELAPOR1 FAM227A KIF5C ADCY2

4.06e-05200855cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellwk_20-22-Mesenchymal-Fibroblast-intermediate_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GSTM5 FBN1 COL21A1 EFEMP2 CNTFR

4.06e-05200855d769723f8fcb37d9b86589e0c41c1d7f16393cfe
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GSTM5 APC LRP1B ADCY2 CNTFR

4.06e-05200855d0812817ef99608994193787a62d39adeb2070ca
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PENK ELAPOR1 FAM227A KIF5C ADCY2

4.06e-05200855a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCellSigmoid-ILC|Sigmoid / Region, Cell class and subclass

COL21A1 DPPA4 ELAPOR1 TRIM54 TRIM74

4.06e-05200855dfb06821f1019833f5d81f9c93808219b5fef407
ToppCellBronchial-NucSeq-Stromal-Chondrocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMA1 HS6ST3 LRP1B ADCY2 CNTFR

4.06e-05200855b7b9441fa7ab0d43741a2ebd5ec1a48d537c6d47
ToppCellSigmoid-(3)_ILC|Sigmoid / shred on region, Cell_type, and subtype

COL21A1 DPPA4 ELAPOR1 TRIM54 TRIM74

4.06e-05200855a7326c43987a5eb4f4f5b48c4252cf4870432e5d
ToppCellSigmoid-(3)_ILC-(30)_ILC|Sigmoid / shred on region, Cell_type, and subtype

COL21A1 DPPA4 ELAPOR1 TRIM54 TRIM74

4.06e-05200855c39de94623383da7b2b260eb016ddaa5da7f4350
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GSTM5 FBN1 COL21A1 EFEMP2 CNTFR

4.06e-05200855a603e8a999612d523bbce9d0feca9296d4a24c97
ToppCellSigmoid-ILC-ILC|Sigmoid / Region, Cell class and subclass

COL21A1 DPPA4 ELAPOR1 TRIM54 TRIM74

4.06e-052008554ac1e6d7f358003e2448eb69e545772cd261c55f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GSTM5 APC LRP1B ADCY2 CNTFR

4.06e-05200855cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellBronchial-NucSeq-Stromal-Chondrocytic-Chondrocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNMA1 HS6ST3 LRP1B ADCY2 CNTFR

4.06e-052008557c673ad0ea503ebd196579684d25d5f9e6a41030
ToppCellCOVID-19-kidney-Epithelial_Doublet|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNTL6 ENTHD1 UNC13C LRP1B

1.12e-041308541ff28e9d3dc9a791e07d815f8fbb48f75d3f275b
ToppCellASK452-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

GALNTL6 PLVAP NCKIPSD ELAPOR1

1.19e-0413285449ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCellCOVID-19-kidney-Technical/muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNTL6 ENTHD1 HS6ST3 LRP1B

1.45e-0413985413247bcb21c57c808657e0f543d6f134eeea7cc1
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP PIK3CD IL18RAP KNL1

1.58e-04142854be63c48794a227ea55978524c0f5935342fc455e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo1_Itga4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

GALNTL6 UCHL3 PENK RSPO1

1.67e-041448547de962346ba9653d90dd13bb7d977fe44d200bba
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNTL6 UNC13C HS6ST3 LRP1B

1.85e-04148854d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM227A MYO15A ADAM8 IL18RAP

1.95e-041508546e806a028c0519489151c181d9907e05289e27e0
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNTL6 ENTHD1 UNC13C LRP1B

1.95e-041508540205318a870e091add66ee4305747dda9f51510d
ToppCellBasal_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

DSC2 ELAPOR1 ENTHD1 UNC13C

2.05e-0415285472499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GALNTL6 COL21A1 ELAPOR1 SCUBE3

2.15e-04154854ec56b7fb88e39041416c384f371c767f3b4e92fa
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS54 FAM227A ADCY2 CFAP46

2.15e-041548549ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CD NCKIPSD XAF1 RSPO1

2.15e-0415485466c93733116e31b65dfb4b0b00de5c39d19cdb84
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS54 FAM227A ADCY2 CFAP46

2.15e-0415485458072ce422d09f2de602580325eaac6c4ec6c136
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

TRIM63 UNC13C ADCY2 CNTFR

2.21e-04155854d7e26696fd9c0a759524f331243db43059b33ed9
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

PLVAP TRIM63 ENTHD1 LRP1B

2.21e-041558547c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

ANO9 COL21A1 FAM227A CFAP46

2.26e-0415685410d191e29b16cae8238e8df6c0ff38882253f34e
ToppCelldroplet-Liver-HEPATOCYTES-1m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIK3CD NCKIPSD XAF1 RSPO1

2.32e-04157854b527e88382c8d21188a0f222b3302523e8816dfc
ToppCellAdult-Mesenchymal-myofibroblast_cell-D122|Adult / Lineage, Cell type, age group and donor

EFEMP2 HS6ST3 RSPO1 ADCY2

2.38e-04158854410fa08c9d880d27e80ec939fa5ba5a41dcb31ab
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PENK KIF5C ADCY2 CFAP46

2.55e-04161854472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP DEF6 IL18RAP KNL1

2.74e-04164854ae09e5aabd1347b865474255e7411c04f63efb3b
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

INCENP PPP2R3B SKA3 KNL1

2.87e-04166854c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GSTM5 TFB1M TRIM63 ENTHD1

2.93e-041678540aa1973141a2437df24c9857cd50ff3dfc7673c0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDK5RAP2 SKA3 KNL1 FANCA

3.00e-04168854d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCell3'_v3-Lung-Lymphocytic_Invariant-Inducer-like|Lung / Manually curated celltypes from each tissue

COL21A1 ELAPOR1 KIF5C IL18RAP

3.00e-04168854b9bde6f542d730682d34a80e1f7f1609e5c699c7
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLVAP PENK TRIM63 CNTFR

3.00e-04168854a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

PPP2R3B SKA3 KNL1 FANCA

3.07e-0416985402fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

INCENP SKA3 KNL1 FANCA

3.07e-04169854b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

INCENP SKA3 KNL1 FANCA

3.07e-04169854e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellCV-Mild-7|CV / Virus stimulation, Condition and Cluster

TNPO1 TRIM73 IARS1 CABIN1

3.14e-0417085425ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ANO9 PIK3CD SCUBE3 IL18RAP

3.14e-04170854aaf29c2d4de172d366cbfc863bc741941667dde1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SKA3 KNL1 FANCA

3.21e-04171854b0373ed8283ee1792b6a490bff93906546978593
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SP140L ZNF723 SKA3 FANCA

3.21e-04171854c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 SKA3 KNL1 FANCA

3.21e-04171854b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

GALNTL6 UNC13C HS6ST3 ADCY2

3.21e-04171854b2e753e811a7639956994609f73efcdb62d04f82
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ENTHD1 UNC13C HS6ST3

3.25e-04708538d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSC2 TRIM55 TRIM63 TRIM54

3.28e-04172854ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCellURO-Lymphocyte-B-Plasmablast|URO / Disease, Lineage and Cell Type

FAM227A ZNF85 SKA3 KNL1

3.28e-0417285448888ef50ac784b38aca81da68f8a94ce09c670d
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSC2 TRIM55 TRIM63 TRIM54

3.28e-04172854bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANO9 TFB1M INCENP FANCA

3.35e-04173854506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

TNPO1 TRIM73 IARS1 CABIN1

3.35e-04173854c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SETD6 ENTHD1 ADAM8 FANCA

3.35e-0417385415af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ANO9 UNC13C KIF5C RSPO1

3.35e-0417385430d67738633493d47f06ae452424382f069b6c0a
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEF6 PRKDC ADAM8 IL18RAP

3.35e-041738542cba41c3d9d3076f703115d19729073a3ac3feb6
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEF6 PRKDC ADAM8 IL18RAP

3.35e-0417385411d69a4ab4a87b8820cd3bd204de8c4124450a90
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP CDK5RAP2 ENTHD1 KNL1

3.43e-0417485465147b0f8c2ccadd5685430d31081520c157536a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

INCENP SKA3 KNL1 FANCA

3.43e-04174854dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

INCENP CDK5RAP2 SKA3 KNL1

3.43e-041748547b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCelldroplet-Heart-4Chambers-21m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GSTM5 PLVAP DSC2 TRIM63

3.43e-04174854f098778ea74012861ec74b425e45776a31f67679
DrugDigoxin [20830-75-5]; Down 200; 5.2uM; PC3; HT_HG-U133A

KLF11 TFB1M ATM KIF5C CAMSAP1 CABIN1 ZBTB24

6.35e-061918376724_DN
Drugchlorpromazine hydrochloride; Down 200; 1uM; MCF7; HT_HG-U133A

DSC2 INCENP GLG1 NCKIPSD ATM KIF5C CABIN1

6.35e-061918375214_DN
DrugDanazol [17230-88-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A

INCENP KDM5C ATM KIF5C CAMSAP1 CABIN1 ZFX

6.80e-061938375315_UP
Drug1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno(3,2-d)pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one

ERBB3 PIK3CD PI4KA PRKDC

7.00e-0634834ctd:C569670
Drug(-)-Eseroline fumarate salt [104015-29-4]; Down 200; 12uM; MCF7; HT_HG-U133A

GBF1 DSC2 INCENP GLG1 APC KIF5C FANCA

7.52e-061968377027_DN
DrugFlavoxate hydrochloride [3717-88-2]; Up 200; 9.4uM; PC3; HT_HG-U133A

FBN1 SP140L DEF6 APC MYO15A CABIN1 FANCA

8.03e-061988376326_UP
DrugAdrenosterone [382-45-6]; Down 200; 13.4uM; PC3; HT_HG-U133A

THADA FBN1 ATR BACH1 NCKIPSD RBM5 CABIN1

8.30e-061998375045_DN
DrugGuanadrel sulfate [22195-34-2]; Down 200; 7.6uM; MCF7; HT_HG-U133A

SFMBT1 SP140L NCKIPSD PRR14L ATM CABIN1 ADAM8

8.58e-062008373438_DN
DrugCortisone [53-06-5]; Down 200; 11uM; HL60; HT_HG-U133A

KLF11 FBN1 PIK3CD KDM5C DEF6 APC ZFX

8.58e-062008372385_DN
DrugAphidicolin

ATR PRKDC ATM

3.06e-0517833ctd:D016590
DrugDigoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT_HG-U133A

ERBB3 DSC2 RBM5 CAMSAP1 ZFX FANCA

3.26e-051668363283_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

SFMBT1 KLF11 RBM5 ZNF85 ATM ZFX

4.66e-051778366340_DN
DrugKetoprofen [22071-15-4]; Down 200; 15.8uM; PC3; HT_HG-U133A

GBF1 GLG1 KCNMA1 APC CDK5RAP2 KIF5C

7.54e-051938364286_DN
DrugAmiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A

RBM5 XAF1 ATM CAMSAP1 CABIN1 ZFX

7.54e-051938363296_UP
DrugAzaguanine-8 [134-58-7]; Down 200; 26.2uM; MCF7; HT_HG-U133A

ERBB3 GLG1 CDK5RAP2 ATM TP53BP1 KIF3A

7.75e-051948361670_DN
DrugMethoxy-8-psoralen [298-81-7]; Up 200; 18.6uM; MCF7; HT_HG-U133A

PIK3CD ELAPOR1 RBM5 CABIN1 ZFX FANCA

7.75e-051948363302_UP
DrugEtidronic acid, disodium salt [7414-83-7]; Down 200; 16uM; MCF7; HT_HG-U133A

DEF6 APC CAMK1 CABIN1 ZFX FANCA

7.75e-051948364387_DN
DrugD-alanyl-D-lactate

TRIM55 TRIM63

7.84e-054832CID005487001
Druglolitrem B

KCNMA1 HMGCR

7.84e-054832CID003086140
DrugAC1L2JQN

KCNMA1 HMGCR

7.84e-054832CID000022092
DrugNSC-85245

CDK5RAP2 TP53BP1 FANCA

7.85e-0523833CID000257281
DrugICI182,780; Down 200; 1uM; PC3; HT_HG-U133A

DSC2 SETD6 EFEMP2 KCNMA1 KIF5C ZFX

7.98e-051958367539_DN
DrugMefenamic acid [61-68-7]; Down 200; 16.6uM; PC3; HT_HG-U133A

ZBTB38 DSC2 INCENP SETD6 RBM5 ATM

7.98e-051958365109_DN
DrugPiromidic acid [19562-30-2]; Down 200; 13.8uM; MCF7; HT_HG-U133A

DSC2 DEF6 APC ATM ZFX FANCA

7.98e-051958364398_DN
DrugBrompheniramine maleate [980-71-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A

KLF11 KDM5C APC CAMSAP1 CABIN1 ZFX

8.21e-051968363271_DN
DrugTodralazine hydrochloride [3778-76-5]; Down 200; 14.8uM; HL60; HT_HG-U133A

SFMBT1 SETD6 APC XAF1 ATM ZFX

8.21e-051968361841_DN
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

GSTM5 INCENP GLG1 EFEMP2 APC ATM

8.21e-051968362329_DN
DrugOxybenzone [131-57-7]; Down 200; 17.6uM; PC3; HT_HG-U133A

THADA KCNMA1 APC CDK5RAP2 KIF5C ADAM8

8.21e-051968366309_DN
DrugHydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A

SFMBT1 GLG1 CDK5RAP2 ATM CABIN1 ZFX

8.21e-051968362119_DN
Drug3-hydroxy-3-methylglutaric acid

PLVAP HMGCR CNTFR FANCA

8.30e-0563834CID000001662
DrugYohimbine hydrochloride [65-19-0]; Down 200; 10.2uM; PC3; HT_HG-U133A

ERBB3 GBF1 DSC2 DEF6 APC ADAM8

8.44e-051978367130_DN
DrugBetaxolol hydrochloride [63659-19-8]; Down 200; 11.6uM; PC3; HT_HG-U133A

THADA EFEMP2 NCKIPSD KIF5C CABIN1 FANCA

8.44e-051978364608_DN
DrugIsradipine [75695-93-1]; Up 200; 10.8uM; MCF7; HT_HG-U133A

EFEMP2 DEF6 KCNMA1 CAMK1 MYO15A LRP1B

8.44e-051978365447_UP
DrugMianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A

THADA GBF1 KDM5C CDK5RAP2 CAMK1 PLXNA2

8.68e-051988362068_DN
DrugTrichlormethiazide [133-67-5]; Up 200; 10.6uM; MCF7; HT_HG-U133A

KCNMA1 ATM CAMK1 CABIN1 PLXNA2 ZFX

8.68e-051988364783_UP
DrugSR-95639A [115767-94-7]; Up 200; 10uM; MCF7; HT_HG-U133A

APC RBM5 PRR14L ATM CAMK1 CABIN1

8.68e-051988364977_UP
DrugChlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A

GBF1 GLG1 SETD6 CABIN1 ADAM8 FANCA

8.68e-051988362100_DN
DrugMethylhydantoin-5-(D) [55147-68-7]; Up 200; 35uM; MCF7; HT_HG-U133A

GSTM5 COL21A1 BACH1 DEF6 MYO15A PLXNA2

8.92e-051998363333_UP
DrugMephentermine hemisulfate [1212-72-2]; Up 200; 9.4uM; MCF7; HT_HG-U133A

INCENP APC CAMK1 CAMSAP1 CNTFR ZFX

9.17e-052008363425_UP
DiseaseBenign neoplasm of stomach

ERBB3 ATR APC ATM

1.35e-0717834C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

ERBB3 ATR APC ATM

1.35e-0717834C0496905
DiseaseCarcinoma in situ of stomach

ERBB3 ATR APC ATM

1.35e-0717834C0154060
DiseaseStomach Carcinoma

ERBB3 ATR APC ATM

3.36e-0721834C0699791
Diseaseendometrial cancer (is_implicated_in)

PIK3CD EFEMP2 APC ATM

3.20e-0636834DOID:1380 (is_implicated_in)
DiseaseGlioma

RAF1 ATR APC XAF1 ATM

4.81e-0687835C0017638
Diseaseataxia telangiectasia (implicated_via_orthology)

ATR ATM

7.82e-062832DOID:12704 (implicated_via_orthology)
Diseaseaortic aneurysm (is_implicated_in)

FBN1 EFEMP2

2.34e-053832DOID:3627 (is_implicated_in)
DiseaseProstatic Neoplasms

ERBB3 ATR PIK3CD EFEMP2 PENK APC PRKDC ATM LRP1B

5.91e-05616839C0033578
DiseaseMalignant neoplasm of prostate

ERBB3 ATR PIK3CD EFEMP2 PENK APC PRKDC ATM LRP1B

5.91e-05616839C0376358
Diseasealcohol use disorder (implicated_via_orthology)

ERBB3 PIK3CD KDM5C KCNMA1 UNC13C

2.29e-04195835DOID:1574 (implicated_via_orthology)
Diseasenasopharynx carcinoma (is_marker_for)

ERBB3 ATR ATM

2.44e-0443833DOID:9261 (is_marker_for)
Diseaseasthma

RAF1 ERBB3 ZBTB38 LEMD2 SCUBE3 CDK5RAP2 UNC13C LRP1B KIF3A

2.62e-04751839MONDO_0004979
Diseasespinal muscular atrophy (implicated_via_orthology)

KIF5B KIF5C

2.78e-049832DOID:12377 (implicated_via_orthology)
Diseasepancreatic cancer (is_implicated_in)

ATR APC ATM FANCA

2.87e-04112834DOID:1793 (is_implicated_in)
DiseaseAdenocarcinoma of lung (disorder)

RAF1 ATR APC PRKDC ATM

2.95e-04206835C0152013
Diseasecolorectal cancer (is_implicated_in)

PIK3CD APC ATM LRP1B

3.85e-04121834DOID:9256 (is_implicated_in)
Diseasecolon cancer (implicated_via_orthology)

ATR APC

4.23e-0411832DOID:219 (implicated_via_orthology)
DiseaseMalignant Neoplasms

ERBB3 ATR APC ATM

4.76e-04128834C0006826
Diseasemotor neuron disease (implicated_via_orthology)

KIF5B KIF5C

5.07e-0412832DOID:231 (implicated_via_orthology)
Diseasegallbladder cancer (is_implicated_in)

APC LRP1B

5.98e-0413832DOID:3121 (is_implicated_in)
Diseaseprostate carcinoma, type 2 diabetes mellitus

THADA ZBTB38 KNL1

6.23e-0459833EFO_0001663, MONDO_0005148
DiseasePROSTATE CANCER, HEREDITARY, 1

INCENP ATM KNL1

6.54e-0460833C4722327
Diseasemelanoma

RAF1 INCENP UBR4 ATM LRP1B

6.86e-04248835C0025202
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ERBB3 ATM

8.02e-0415832C0496930
DiseaseBenign neoplasm of bladder

ERBB3 ATM

8.02e-0415832C0154017
DiseaseCarcinoma in situ of bladder

ERBB3 ATM

8.02e-0415832C0154091
DiseaseAutosomal recessive primary microcephaly

CDK5RAP2 KNL1

8.02e-0415832cv:C3711387
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

KDM5C KCNMA1 ATM LRP1B

8.21e-04148834C0279702
DiseaseColonic Neoplasms

GSTM5 APC XAF1 TP53BP1

9.07e-04152834C0009375
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

PIK3CD ATM

9.14e-0416832C0334634
DiseaseProstate cancer, familial

INCENP ATM KNL1

9.84e-0469833C2931456
DiseaseNon-Small Cell Lung Carcinoma

RAF1 APC KIF5B TP53BP1

9.99e-04156834C0007131
Diseasecardiomyopathy (implicated_via_orthology)

RAF1 ERBB3 LEMD2

1.07e-0371833DOID:0050700 (implicated_via_orthology)
DiseaseMalignant tumor of colon

GSTM5 APC XAF1 TP53BP1

1.07e-03159834C0007102
Diseasemonocyte count

TNPO1 THADA PLVAP PIK3CD GLG1 PI4KA EFEMP2 PRKDC ATM CABIN1 FANCA

1.16e-0313208311EFO_0005091
Diseasenucleotide measurement

UNC13C HMGCR PLXNA2

1.16e-0373833EFO_0010513
DiseaseCarcinoma of bladder

ERBB3 ATM

1.16e-0318832C0699885
Diseaseovulation

FAM227A FANCA

1.30e-0319832GO_0030728
Diseasereceptive language perception

TNPO1 KIF3A

1.30e-0319832EFO_0005686
DiseaseAdenocarcinoma of prostate

ATM FANCA

1.44e-0320832C0007112
DiseaseStomach Neoplasms

ERBB3 ATR APC XAF1 ATM

1.53e-03297835C0038356
DiseaseMalignant neoplasm of stomach

ERBB3 ATR APC XAF1 ATM

1.60e-03300835C0024623
DiseaseAutosomal Recessive Primary Microcephaly

CDK5RAP2 KNL1

1.74e-0322832C3711387
DiseasePrimary microcephaly

CDK5RAP2 KNL1

1.74e-0322832C0431350
Diseaserefractive error, age at onset, Myopia

ZBTB38 FBN1 BACH1 KCNMA1

2.18e-03193834EFO_0004847, HP_0000545, MONDO_0004892
Diseasenevus count, cutaneous melanoma

ANO9 ATM FANCA

2.18e-0391833EFO_0000389, EFO_0004632
Diseasebreast cancer (implicated_via_orthology)

ATR APC

2.25e-0325832DOID:1612 (implicated_via_orthology)
Diseaserefractive error

ZBTB38 FBN1 KCNMA1 ENTHD1 ATM

2.29e-03326835MONDO_0004892
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

APC ATM

2.43e-0326832C0009405
DiseaseEndogenous Hyperinsulinism

FBN1 FANCA

2.43e-0326832C1257963
DiseaseExogenous Hyperinsulinism

FBN1 FANCA

2.43e-0326832C1257964
DiseaseCompensatory Hyperinsulinemia

FBN1 FANCA

2.43e-0326832C1257965
DiseaseAdenocarcinoma of large intestine

APC PRKDC ATM

2.54e-0396833C1319315
Diseaselymphocyte count

TNPO1 ERBB3 THADA ZBTB38 FBN1 GBF1 PIK3CD DEF6 ATM IL18RAP KNL1

2.62e-0314648311EFO_0004587
DiseaseBone Diseases, Developmental

NANS KIF3A

2.62e-0327832C0005941
Diseasecolorectal adenocarcinoma (is_marker_for)

RAF1 ERBB3

2.62e-0327832DOID:0050861 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
EARECENMFPKKSCA

FAM227A

396

F5H4B4
CVRACPPDKMEVDKN

ERBB3

301

P21860
GVPECRDLQVMLKCD

BACH1

266

O14867
SKDPGKLIEMECLEC

CFAP46

321

Q8IYW2
LEDNMLCPKCVHRNK

DPPA4

281

Q7L190
DFVKMCLEANIPLEK

CGGBP1

106

Q9UFW8
CRPKKDMCDLEEFCD

ADAM8

466

P78325
INRCVALKLCDFEMP

ANO9

396

A1A5B4
YCPEQMKLDDICLKE

CAMSAP1

261

Q5T5Y3
NLEPKFRTLAEACMK

DSC2

886

Q02487
LIQCLKEEKSQMACP

CDK5RAP2

236

Q96SN8
NCPKAMKRLVADCVK

RAF1

576

P04049
DCLCQMLDLVKPRTE

PPP2R3B

436

Q9Y5P8
ECNIKVMCRFRPLNE

KIF5B

6

P33176
LACVMECEGKLPSLK

PENK

46

P01210
LMDEPLLCKEREVAC

ENTHD1

131

Q8IYW4
DVACCVKMILEVKPQ

IL18RAP

136

O95256
NKKCIPMDLQCDRLD

LRP1B

3771

Q9NZR2
PTVCELCFVKLKLLM

KCNMA1

616

Q12791
MKRIFEPKCLDAFLN

GSTM5

166

P46439
LRMDPKCSFVEKERQ

INCENP

526

Q9NQS7
MKLLPVDCERKTDEF

LEMD2

246

Q8NC56
LVEKMERCNPLFMRC

MYO15A

1781

Q9UKN7
QKKVPDNCCRREPML

HMGCR

361

P04035
LDMKDQSCKPCAEGR

ELAPOR1

101

Q6UXG2
VQALCLPLDKDKFEM

PLVAP

221

Q9BX97
RLCIGECKPEFMTKS

PLXNA2

931

O75051
RPASLEKVQKLLCMC

PI4KA

46

P42356
EKVQKLLCMCPVDFH

PI4KA

51

P42356
MLLCDKDEEKANYCP

KNL1

1346

Q8NG31
DLDMCPLYKLQKTEC

PRSS54

191

Q6PEW0
CRPLNEREKSMCYKQ

KIF3A

21

Q9Y496
KMACLLCRRQFPNKD

RBM5

646

P52756
TNCVPAIMEKKDCPR

HS6ST3

216

Q8IZP7
LMEKDPEKRFTCEQA

CAMK1

256

Q14012
KMACKEDVLKLCPNI

GLG1

756

Q92896
CEILQLLKPMCEVKT

ATM

1821

Q13315
LLKPMCEVKTDFCQT

ATM

1826

Q13315
AKENECMRIKILGDC

ADCY2

326

Q08462
CKPKDDLRKDCRLME

ATR

2326

Q13535
PCLRKDSLRMFLKCD

CABIN1

206

Q9Y6J0
FKDINECKMIPSLCT

FBN1

1026

P35555
MVDFILAKCQTKCPL

FANCA

1151

O15360
IMVCEKDPALKNRCH

CNTFR

151

P26992
KQENGRKEMPICCII

CCDC144B

706

Q3MJ40
VMKQKLCEESVCPTR

COL21A1

206

Q96P44
LPDRDGKRCMFCVKT

DEF6

271

Q9H4E7
VALECIKQCDPEKMI

GBF1

1106

Q92538
EKKFVCPVCDRRFMR

KLF11

451

O14901
NECLTIPEACKGEMK

EFEMP2

56

O95967
FMLQPDRKTCKDIDE

SCUBE3

266

Q8IX30
LNIQACCRMDKKPDS

LRCH2

301

Q5VUJ6
VCRSLKDCEMEKCPD

PRR14L

1136

Q5THK1
CNPAEKKIFMARCDP

GALNTL6

561

Q49A17
MKENHPECFCKILKI

THADA

1596

Q6YHU6
PECFCKILKILHCMD

THADA

1601

Q6YHU6
ECSIKVMCRFRPLNE

KIF5C

6

O60282
AMSKKCPICRVDIET

RNF165

326

Q6ZSG1
ARNPDMNKCIKCKIE

RSPO1

86

Q2MKA7
LKVLCMPAEEFRELK

SETD6

371

Q8TBK2
PTKQLLPCEMACNEK

NANS

276

Q9NR45
LPCEMACNEKLGKSV

NANS

281

Q9NR45
KSLCDVYRKMCDEDP

TFB1M

301

Q8WVM0
CMDFNIIRKDSLPVC

IARS1

336

P41252
RQMCPEEQLKCEFLL

SP140L

466

Q9H930
LTDADPEVCKKMCKR

NCKIPSD

421

Q9NZQ3
PEVCKKMCKRNEFES

NCKIPSD

426

Q9NZQ3
ICPAVCVLMKLSFDE

APC

446

P25054
NLEKQLICPICLEMF

TRIM63

16

Q969Q1
CALKMDDFECVTPKL

SKA3

206

Q8IX90
CPICLEVFKESLMLQ

TRIM74

16

Q86UV6
EKQLICPICLEMFSK

TRIM54

21

Q9BYV2
IEVCKKFMERDPDEL

UCHL3

206

P15374
EKQLICPICLEMFTK

TRIM55

21

Q9BYV6
PKASMVVKDCVRACL

UNC13C

1536

Q8NB66
LQLRKGCESVDECKM

ZNF723

111

P0DPD5
ERPVECKFCKLDMQL

XAF1

81

Q6GPH4
LCDPEVNDFRAKMCQ

PIK3CD

131

O00329
LCLQKEMPKKECSEA

TP53BP1

701

Q12888
INPKDDLRDMFCKIL

TNPO1

851

Q92973
PKMQLVCCRAIVKVF

PRKDC

451

P78527
PECKDCHRKFMDVSQ

ZBTB24

406

O43167
SMEKCLQDFCLPFLR

UBR3

1641

Q6ZT12
KEMPFKCDICLLTFS

ZFX

601

P17010
CPICLEVFKESLMLQ

TRIM73

16

Q86UV7
NLPLRKGCESMDECK

ZNF85

111

Q03923
QECMDLKLGPAIKLC

SFMBT1

836

Q9UHJ3
TKEMPKLQCELCDGD

ZBTB38

976

Q8NAP3
EKPFECDICDMRFIQ

ZNF740

126

Q8NDX6
PLMRDIKNKICQDCD

UBR4

4381

Q5T4S7
SKEMPFKCDICLLTF

ZFY

596

P08048
ELICKMAACPEKLDL

KDM5C

646

P41229