Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

JAG2 CRELD1 VLDLR FBLN7 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLB DSG3 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1

3.31e-117497619GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

CRELD1 MFGE8 THBS1 FBN1 FBN2 HMCN2 LAMA2 LAMA3 COL1A1

3.97e-08188769GO:0005201
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

VLDLR LRP1 LDLR SORL1

3.41e-0716764GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

VLDLR LRP1 LDLR SORL1

1.10e-0621764GO:0030228
GeneOntologyMolecularFunctionNotch binding

JAG2 NOTCH2NLB NOTCH2NLA NOTCH1

3.18e-0627764GO:0005112
GeneOntologyMolecularFunctionintegrin binding

MFGE8 THBS1 FBN1 ADAM9 ITGA4 ITGAD ITGB8

4.63e-06175767GO:0005178
GeneOntologyMolecularFunctionlipoprotein particle binding

VLDLR THBS1 LDLR SORL1

9.28e-0635764GO:0071813
GeneOntologyMolecularFunctionprotein-lipid complex binding

VLDLR THBS1 LDLR SORL1

9.28e-0635764GO:0071814
GeneOntologyMolecularFunctioncargo receptor activity

VLDLR INSR LRP1 LDLR SORL1

1.81e-0585765GO:0038024
GeneOntologyMolecularFunctionlow-density lipoprotein particle binding

THBS1 LDLR SORL1

4.15e-0518763GO:0030169
GeneOntologyMolecularFunctionprotease binding

CASP8AP2 THBS1 LRP1 FAS LDLR COL1A1

6.60e-05181766GO:0002020
GeneOntologyMolecularFunctionvery-low-density lipoprotein particle receptor activity

VLDLR LDLR

8.54e-054762GO:0030229
GeneOntologyMolecularFunctionsulfur compound binding

FBLN7 THBS1 FBN1 INSR LRP1 LTF APOH

2.28e-04323767GO:1901681
GeneOntologyMolecularFunctionstructural molecule activity

CRELD1 MFGE8 THBS1 FBN1 FBN2 HMCN2 INSR LAMA2 LAMA3 ERVK-5 COL1A1

5.29e-048917611GO:0005198
GeneOntologyMolecularFunctionamyloid-beta binding

INSR LRP1 LDLR SORL1

6.21e-04102764GO:0001540
GeneOntologyMolecularFunctionheparin binding

FBLN7 THBS1 FBN1 LTF APOH

8.29e-04192765GO:0008201
GeneOntologyMolecularFunctionextracellular matrix constituent conferring elasticity

FBN1 FBN2

9.21e-0412762GO:0030023
GeneOntologyMolecularFunctionclathrin heavy chain binding

LRP1 LDLR

9.21e-0412762GO:0032050
GeneOntologyMolecularFunctionproteoglycan binding

FBLN7 THBS1 LRP1

9.68e-0451763GO:0043394
GeneOntologyMolecularFunctionstructural molecule activity conferring elasticity

FBN1 FBN2

1.26e-0314762GO:0097493
GeneOntologyMolecularFunctionpeptide binding

PCSK5 INSR LRP1 LDLR BRAP SORL1

1.34e-03318766GO:0042277
GeneOntologyMolecularFunctioncell adhesion molecule binding

FLNB MFGE8 THBS1 FBN1 ADAM9 ITGA4 ITGAD ITGB8

1.97e-03599768GO:0050839
GeneOntologyMolecularFunctionapolipoprotein binding

VLDLR LRP1

2.60e-0320762GO:0034185
GeneOntologyMolecularFunctionpeptidase regulator activity

CASP8AP2 THBS1 LTF TFPI SORL1

2.98e-03257765GO:0061134
GeneOntologyMolecularFunctionglycosaminoglycan binding

FBLN7 THBS1 FBN1 LTF APOH

3.57e-03268765GO:0005539
GeneOntologyMolecularFunctioncollagen binding

THBS1 ADAM9 P3H4

3.65e-0381763GO:0005518
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

PCSK5 ADAM9 LAMA2 ITGA4 TEC ITGAD ITGB8

3.38e-07124757GO:0007229
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

THBS1 FBN1 FBN2 ADAM9 TMPRSS6 WIF1 LRP1 ITGB8 NOTCH1 NOTCH2 SORL1

5.90e-074457511GO:0141091
GeneOntologyBiologicalProcesscirculatory system development

PCSK5 CRELD1 SETDB2 MFGE8 THBS1 NPR1 SCUBE1 FBN1 INSR WIF1 LRP1 ITGA4 APOH LDLR ITGB8 NOTCH1 NOTCH2 COL1A1 LARGE1

6.50e-0714427519GO:0072359
GeneOntologyBiologicalProcessosteoclast development

FBN1 P2RX5 LTF NOTCH2

1.12e-0622754GO:0036035
GeneOntologyBiologicalProcessbone cell development

FBN1 P2RX5 LTF NOTCH2

1.12e-0622754GO:0098751
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

THBS1 FBN1 FBN2 ADAM9 TMPRSS6 WIF1 LRP1 ITGB8 NOTCH1 NOTCH2 SORL1

1.29e-064827511GO:0007178
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

JAG2 NOTCH2NLB NOTCH2NLA NOTCH2NLC NOTCH1

1.39e-0653755GO:0045747
GeneOntologyBiologicalProcessskeletal system development

JAG2 PAPPA2 PCSK5 THBS1 FBN1 FBN2 P2RX5 LTF ITGB8 NOTCH2 COL1A1 LARGE1

2.09e-066157512GO:0001501
GeneOntologyBiologicalProcessheart development

PCSK5 CRELD1 SETDB2 THBS1 SCUBE1 FBN1 INSR WIF1 LRP1 ITGA4 NOTCH1 NOTCH2 LARGE1

3.06e-067577513GO:0007507
GeneOntologyBiologicalProcessregeneration

EYS P2RX5 LRP1 TEC APOH FAS NOTCH1 LARGE1

3.70e-06252758GO:0031099
GeneOntologyBiologicalProcessbone development

PAPPA2 THBS1 FBN1 P2RX5 LTF NOTCH2 COL1A1 LARGE1

5.21e-06264758GO:0060348
GeneOntologyBiologicalProcessregulation of osteoclast development

FBN1 LTF NOTCH2

1.29e-0513753GO:2001204
GeneOntologyBiologicalProcessleft/right axis specification

SETDB2 NOTCH1 NOTCH2

1.63e-0514753GO:0070986
GeneOntologyBiologicalProcesscell-substrate adhesion

PCSK5 THBS1 ADAM9 LRP1 ITGA4 ITGAD ITGB8 NOTCH1 COL1A1

1.75e-05410759GO:0031589
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

EPHB6 THBS1 NPR1 FBN1 FBN2 ADAM9 TMPRSS6 INSR WIF1 LRP1 ITGB8 NOTCH1 NOTCH2 SORL1 COL1A1

1.99e-0511867515GO:0007167
GeneOntologyBiologicalProcesscell adhesion mediated by integrin

FBN1 ADAM9 ITGA4 ITGAD ITGB8

2.02e-0591755GO:0033627
GeneOntologyBiologicalProcessregulation of triglyceride catabolic process

APOH LDLR SORL1

2.04e-0515753GO:0010896
GeneOntologyBiologicalProcessblood vessel development

PCSK5 MFGE8 THBS1 NPR1 WIF1 LRP1 APOH LDLR ITGB8 NOTCH1 NOTCH2 COL1A1 LARGE1

2.73e-059297513GO:0001568
GeneOntologyBiologicalProcesstissue regeneration

EYS P2RX5 TEC NOTCH1 LARGE1

3.04e-0599755GO:0042246
GeneOntologyBiologicalProcessgrowth

PAPPA2 THBS1 NPR1 EYS KMT2D P2RX5 CGRRF1 INSR LRP1 ITGA4 TRIM40 TEC NOTCH1 NOTCH2 LARGE1

3.19e-0512357515GO:0040007
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

THBS1 FBN1 FBN2 TMPRSS6 LRP1 NOTCH1 NOTCH2 SORL1

3.75e-05347758GO:0090092
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

3.90e-053752GO:0071228
GeneOntologyBiologicalProcessvasculature development

PCSK5 MFGE8 THBS1 NPR1 WIF1 LRP1 APOH LDLR ITGB8 NOTCH1 NOTCH2 COL1A1 LARGE1

4.23e-059697513GO:0001944
GeneOntologyBiologicalProcessanimal organ morphogenesis

JAG2 PAPPA2 SETDB2 THBS1 FBN2 INSR LAMA2 LAMA3 LTF NOTCH1 NOTCH2 CRB1 RHO COL1A1 LARGE1

4.36e-0512697515GO:0009887
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

THBS1 FBN1 FBN2 ADAM9 TMPRSS6 INSR LRP1 ITGB8 NOTCH1 NOTCH2 SORL1 COL1A1

5.31e-058507512GO:0071363
GeneOntologyBiologicalProcesscell-matrix adhesion

PCSK5 THBS1 ADAM9 LRP1 ITGA4 ITGAD ITGB8

5.66e-05270757GO:0007160
GeneOntologyBiologicalProcessappendage morphogenesis

PCSK5 FBN2 AFF3 NOTCH1 NOTCH2 LARGE1

5.79e-05185756GO:0035107
GeneOntologyBiologicalProcesslimb morphogenesis

PCSK5 FBN2 AFF3 NOTCH1 NOTCH2 LARGE1

5.79e-05185756GO:0035108
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

JAG2 NOTCH2NLB NOTCH2NLA NOTCH2NLC NOTCH1

5.99e-05114755GO:0008593
GeneOntologyBiologicalProcessresponse to growth factor

THBS1 FBN1 FBN2 ADAM9 TMPRSS6 INSR LRP1 ITGB8 NOTCH1 NOTCH2 SORL1 COL1A1

7.65e-058837512GO:0070848
GeneOntologyBiologicalProcesssequestering of TGFbeta in extracellular matrix

FBN1 FBN2

7.79e-054752GO:0035583
GeneOntologyBiologicalProcessaxon guidance

EPHB6 HMCN2 LRP1 LAMA2 LAMA3 NOTCH1 NOTCH2

7.95e-05285757GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

EPHB6 HMCN2 LRP1 LAMA2 LAMA3 NOTCH1 NOTCH2

8.12e-05286757GO:0097485
GeneOntologyBiologicalProcessresponse to abiotic stimulus

PAPPA2 VLDLR NR2F6 THBS1 EYS P2RX5 PDE8B DNAJA2 FAS NOTCH1 CRB1 RHO COL1A1 TG LARGE1

9.65e-0513617515GO:0009628
GeneOntologyBiologicalProcessregulation of cell migration

PCSK5 THBS1 FBN2 ADAM9 INSR LRP1 LAMA2 LAMA3 ITGA4 APOH FAS NOTCH1 SORL1 COL1A1

1.04e-0412117514GO:0030334
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

FBN1 TMPRSS6 NOTCH1 NOTCH2 SORL1

1.16e-04131755GO:0030510
GeneOntologyBiologicalProcessNotch signaling pathway

JAG2 NOTCH2NLB NOTCH2NLA NOTCH2NLC NOTCH1 NOTCH2

1.16e-04210756GO:0007219
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

THBS1 FBN1 FBN2 TMPRSS6 LRP1 NOTCH1 NOTCH2 SORL1

1.24e-04412758GO:0090287
GeneOntologyBiologicalProcesscardiac septum development

PCSK5 CRELD1 LRP1 NOTCH1 NOTCH2

1.29e-04134755GO:0003279
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LDLR

1.30e-045752GO:1905167
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

FBN1 FBN2 TMPRSS6 LRP1 NOTCH1 SORL1

1.43e-04218756GO:0090101
GeneOntologyBiologicalProcessnegative regulation of cell-substrate adhesion

THBS1 LRP1 NOTCH1 COL1A1

1.53e-0474754GO:0010812
GeneOntologyBiologicalProcesslimb development

PCSK5 FBN2 AFF3 NOTCH1 NOTCH2 LARGE1

1.65e-04224756GO:0060173
GeneOntologyBiologicalProcessappendage development

PCSK5 FBN2 AFF3 NOTCH1 NOTCH2 LARGE1

1.65e-04224756GO:0048736
GeneOntologyBiologicalProcessglial cell differentiation

LRP1 LAMA2 LDLR NOTCH1 NOTCH2 CRB1 LARGE1

1.66e-04321757GO:0010001
GeneOntologyBiologicalProcesstriglyceride catabolic process

APOH LDLR SORL1

1.75e-0430753GO:0019433
GeneOntologyBiologicalProcessgliogenesis

LRP1 LAMA2 FAS LDLR NOTCH1 NOTCH2 CRB1 LARGE1

1.80e-04435758GO:0042063
GeneOntologyBiologicalProcessregulation of cell motility

PCSK5 THBS1 FBN2 ADAM9 INSR LRP1 LAMA2 LAMA3 ITGA4 APOH FAS NOTCH1 SORL1 COL1A1

1.85e-0412807514GO:2000145
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

JAG2 NOTCH1

1.94e-046752GO:0060120
GeneOntologyBiologicalProcessnegative regulation of osteoclast development

FBN1 LTF

1.94e-046752GO:2001205
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

JAG2 NOTCH1

1.94e-046752GO:0009912
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

FBN1 TMPRSS6 NOTCH1 SORL1

2.07e-0480754GO:0030514
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

THBS1 FBN1 TMPRSS6 NOTCH1 SORL1

2.18e-04150755GO:0090288
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

THBS1 FBN1 FBN2 ADAM9 LRP1 ITGB8 COL1A1

2.20e-04336757GO:0071560
GeneOntologyBiologicalProcessdetermination of left/right symmetry

PCSK5 SETDB2 WIF1 NOTCH1 NOTCH2

2.46e-04154755GO:0007368
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

THBS1 FBN1 FBN2 ADAM9 LRP1 ITGB8 COL1A1

2.49e-04343757GO:0071559
GeneOntologyBiologicalProcessregulation of locomotion

PCSK5 THBS1 FBN2 ADAM9 INSR LRP1 LAMA2 LAMA3 ITGA4 APOH FAS NOTCH1 SORL1 COL1A1

2.69e-0413277514GO:0040012
GeneOntologyBiologicalProcessnegative regulation of endothelial cell chemotaxis

THBS1 NOTCH1

2.71e-047752GO:2001027
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LDLR

2.71e-047752GO:1904352
GeneOntologyBiologicalProcesspositive regulation of protein kinase activity

VLDLR THBS1 FBN1 ADAM9 INSR LTF NOTCH2

2.82e-04350757GO:0045860
GeneOntologyBiologicalProcessleft/right pattern formation

PCSK5 SETDB2 WIF1 NOTCH1 NOTCH2

3.11e-04162755GO:0060972
GeneOntologyBiologicalProcessheterochromatin formation

SETDB2 RIF1 KMT2D MOV10L1 RRP8

3.20e-04163755GO:0031507
GeneOntologyBiologicalProcessretina morphogenesis in camera-type eye

NOTCH1 CRB1 RHO LARGE1

3.25e-0490754GO:0060042
GeneOntologyBiologicalProcessdetermination of bilateral symmetry

PCSK5 SETDB2 WIF1 NOTCH1 NOTCH2

3.39e-04165755GO:0009855
GeneOntologyBiologicalProcessspecification of symmetry

PCSK5 SETDB2 WIF1 NOTCH1 NOTCH2

3.39e-04165755GO:0009799
GeneOntologyBiologicalProcessresponse to tumor necrosis factor

THBS1 ADAM9 INSR AFF3 FAS COL1A1

3.54e-04258756GO:0034612
GeneOntologyBiologicalProcessmaintenance of protein location in extracellular region

FBN1 FBN2

3.60e-048752GO:0071694
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

LRP1 LDLR

3.60e-048752GO:0150094
GeneOntologyBiologicalProcessFas signaling pathway

CASP8AP2 FAS

3.60e-048752GO:0036337
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

NOTCH1 NOTCH2 CRB1 RHO LARGE1

3.99e-04171755GO:0048593
GeneOntologyBiologicalProcessamyloid-beta clearance

INSR LRP1 LDLR

4.14e-0440753GO:0097242
GeneOntologyBiologicalProcessdevelopmental growth

THBS1 EYS KMT2D P2RX5 INSR LRP1 ITGA4 TEC NOTCH1 NOTCH2 LARGE1

4.33e-049117511GO:0048589
GeneOntologyBiologicalProcessextracellular matrix organization

TMPRSS6 LRP1 LAMA2 P3H4 NOTCH1 COL1A1 LARGE1

4.40e-04377757GO:0030198
GeneOntologyBiologicalProcessneutral lipid catabolic process

APOH LDLR SORL1

4.46e-0441753GO:0046461
GeneOntologyBiologicalProcessacylglycerol catabolic process

APOH LDLR SORL1

4.46e-0441753GO:0046464
GeneOntologyBiologicalProcessextracellular structure organization

TMPRSS6 LRP1 LAMA2 P3H4 NOTCH1 COL1A1 LARGE1

4.47e-04378757GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

TMPRSS6 LRP1 LAMA2 P3H4 NOTCH1 COL1A1 LARGE1

4.54e-04379757GO:0045229
GeneOntologyBiologicalProcessatrioventricular node development

NOTCH1 NOTCH2

4.62e-049752GO:0003162
GeneOntologyBiologicalProcessregulation of embryonic development

INSR LAMA2 LAMA3 NOTCH1

4.67e-0499754GO:0045995
GeneOntologyBiologicalProcessregulation of cell adhesion

JAG2 EPHB6 PCSK5 THBS1 ADAM9 LRP1 LAMA2 LAMA3 ITGA4 NOTCH1 COL1A1

5.01e-049277511GO:0030155
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

THBS1 FBN1 FBN2 ADAM9 LRP1 ITGB8

5.05e-04276756GO:0007179
GeneOntologyBiologicalProcessneural retina development

NOTCH1 CRB1 RHO LARGE1

5.23e-04102754GO:0003407
GeneOntologyBiologicalProcesspost-embryonic animal morphogenesis

CRB1 LARGE1

5.76e-0410752GO:0009886
GeneOntologyBiologicalProcesspositive regulation of triglyceride catabolic process

APOH LDLR

5.76e-0410752GO:0010898
GeneOntologyBiologicalProcessastrocyte differentiation

LRP1 LDLR NOTCH1 LARGE1

5.84e-04105754GO:0048708
GeneOntologyBiologicalProcessmyeloid cell development

FBN1 P2RX5 LTF NOTCH2

6.72e-04109754GO:0061515
GeneOntologyBiologicalProcesspositive regulation of kinase activity

VLDLR THBS1 FBN1 ADAM9 INSR LTF NOTCH2

6.73e-04405757GO:0033674
GeneOntologyBiologicalProcesssequestering of extracellular ligand from receptor

FBN1 FBN2

7.02e-0411752GO:0035581
GeneOntologyBiologicalProcessapoptotic cell clearance

MFGE8 THBS1 LRP1

7.10e-0448753GO:0043277
GeneOntologyBiologicalProcesshindlimb morphogenesis

AFF3 NOTCH1 LARGE1

7.54e-0449753GO:0035137
GeneOntologyBiologicalProcessBMP signaling pathway

FBN1 TMPRSS6 NOTCH1 NOTCH2 SORL1

7.59e-04197755GO:0030509
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LDLR

8.41e-0412752GO:1905165
GeneOntologyBiologicalProcessnegative regulation of gene expression, epigenetic

SETDB2 RIF1 KMT2D MOV10L1 RRP8

8.68e-04203755GO:0045814
GeneOntologyBiologicalProcesseye morphogenesis

NOTCH1 NOTCH2 CRB1 RHO LARGE1

8.87e-04204755GO:0048592
GeneOntologyBiologicalProcessmyeloid leukocyte differentiation

FBN1 P2RX5 LTF ITGB8 NOTCH2 LARGE1

9.58e-04312756GO:0002573
GeneOntologyBiologicalProcessregulation of Schwann cell migration

LRP1 FAS

9.92e-0413752GO:1900147
GeneOntologyBiologicalProcessextracellular regulation of signal transduction

FBN1 FBN2

9.92e-0413752GO:1900115
GeneOntologyBiologicalProcessextracellular negative regulation of signal transduction

FBN1 FBN2

9.92e-0413752GO:1900116
GeneOntologyBiologicalProcessresponse to nutrient levels

FBN1 INSR MTMR3 RRP8 FAS LDLR SORL1 COL1A1

1.03e-03566758GO:0031667
GeneOntologyBiologicalProcessaxonogenesis

EPHB6 HMCN2 LRP1 LAMA2 LAMA3 ITGA4 NOTCH1 NOTCH2

1.03e-03566758GO:0007409
GeneOntologyCellularComponentcell surface

EPHB6 VLDLR MFGE8 THBS1 SCUBE1 ADAM9 INSR WIF1 LRP1 LTF ITGA4 APOH ITGAD FAS LDLR ITGB8 NOTCH1 NOTCH2 TFPI SORL1

1.34e-0911117520GO:0009986
GeneOntologyCellularComponentcollagen-containing extracellular matrix

CRELD1 MFGE8 THBS1 EYS FBN1 FBN2 HMCN2 LAMA2 LAMA3 APOH COL1A1

2.84e-065307511GO:0062023
GeneOntologyCellularComponentextracellular matrix

CRELD1 FBLN7 MFGE8 THBS1 EYS FBN1 FBN2 HMCN2 LAMA2 LAMA3 APOH COL1A1

3.53e-066567512GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

CRELD1 FBLN7 MFGE8 THBS1 EYS FBN1 FBN2 HMCN2 LAMA2 LAMA3 APOH COL1A1

3.65e-066587512GO:0030312
GeneOntologyCellularComponentexternal side of plasma membrane

MFGE8 THBS1 SCUBE1 ADAM9 INSR LRP1 ITGA4 ITGAD FAS LDLR

1.59e-055197510GO:0009897
GeneOntologyCellularComponentanchoring junction

FLNB FBLN7 FLNC DSG3 ADAM9 LRP1 LAMA3 ITGA4 TEC ITGB8 NOTCH1 CRB1 RHO

3.97e-059767513GO:0070161
GeneOntologyCellularComponentreceptor complex

VLDLR NPR1 INSR LRP1 ITGA4 ITGAD LDLR ITGB8 NOTCH1 NOTCH2

4.16e-055817510GO:0043235
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA2 ITGA4 ITGAD ITGB8

5.99e-0559754GO:0098636
GeneOntologyCellularComponentcell-substrate junction

FLNB FBLN7 FLNC ADAM9 LRP1 LAMA3 ITGA4 ITGB8

1.86e-04443758GO:0030055
GeneOntologyCellularComponentintegrin complex

ITGA4 ITGAD ITGB8

2.04e-0432753GO:0008305
GeneOntologyCellularComponentside of membrane

MFGE8 THBS1 SCUBE1 ADAM9 INSR LRP1 ITGA4 ITGAD FAS LDLR TFPI

2.74e-048757511GO:0098552
GeneOntologyCellularComponentmale pronucleus

RIF1 TET3

3.51e-048752GO:0001940
GeneOntologyCellularComponentlipoprotein particle

VLDLR APOH LDLR

5.29e-0444753GO:1990777
GeneOntologyCellularComponentplasma lipoprotein particle

VLDLR APOH LDLR

5.29e-0444753GO:0034358
GeneOntologyCellularComponentfemale pronucleus

RIF1 TET3

5.61e-0410752GO:0001939
GeneOntologyCellularComponentprotein-lipid complex

VLDLR APOH LDLR

6.42e-0447753GO:0032994
GeneOntologyCellularComponentfocal adhesion

FLNB FBLN7 FLNC ADAM9 LRP1 ITGA4 ITGB8

8.96e-04431757GO:0005925
GeneOntologyCellularComponentmicrofibril

FBN1 FBN2

9.66e-0413752GO:0001527
GeneOntologyCellularComponentbasement membrane

FBN1 HMCN2 LAMA2 LAMA3

9.75e-04122754GO:0005604
GeneOntologyCellularComponentsomatodendritic compartment

EPHB6 PCSK5 FLNB HMCN2 AZIN2 INSR LRP1 LAMA2 ITGA4 FAS LDLR SORL1

1.34e-0312287512GO:0036477
GeneOntologyCellularComponentneuronal cell body

PCSK5 FLNB HMCN2 AZIN2 INSR LRP1 ITGA4 FAS SORL1

2.94e-03835759GO:0043025
GeneOntologyCellularComponentclathrin-coated pit

VLDLR LRP1 LDLR

2.99e-0380753GO:0005905
GeneOntologyCellularComponentsecretory granule

MFGE8 THBS1 SCCPDH UBR4 LRP1 LTF APOH FAS NOTCH1 COL1A1

3.26e-0310147510GO:0030141
GeneOntologyCellularComponenttriglyceride-rich plasma lipoprotein particle

VLDLR APOH

3.33e-0324752GO:0034385
GeneOntologyCellularComponentvery-low-density lipoprotein particle

VLDLR APOH

3.33e-0324752GO:0034361
GeneOntologyCellularComponentpronucleus

RIF1 TET3

4.52e-0328752GO:0045120
GeneOntologyCellularComponentcell-cell junction

DSG3 LAMA3 ITGA4 TEC NOTCH1 CRB1 RHO

5.26e-03591757GO:0005911
GeneOntologyCellularComponentapical part of cell

PAPPA2 VLDLR LRP1 FAS LDLR NOTCH1 CRB1

5.31e-03592757GO:0045177
HumanPhenoAbnormal mitral valve physiology

FLNC KMT2D FBN1 FBN2 FAS LDLR NOTCH1 NOTCH2 COL1A1

1.72e-06180349HP:0031481
HumanPhenoAbnormal atrioventricular valve physiology

FLNC KMT2D FBN1 FBN2 FAS LDLR NOTCH1 NOTCH2 COL1A1

7.51e-06215349HP:0031650
HumanPhenoElbow dislocation

FLNB FBN1 FBN2 AFF3 NOTCH2 COL1A1

1.56e-0584346HP:0003042
HumanPhenoMitral stenosis

KMT2D FBN1 NOTCH1 NOTCH2

3.03e-0528344HP:0001718
HumanPhenoAbnormal mitral valve morphology

FLNC KMT2D FBN1 FBN2 FAS LDLR NOTCH1 NOTCH2 COL1A1

3.17e-05257349HP:0001633
HumanPhenoUpper extremity joint dislocation

FLNB FBN1 FBN2 AFF3 NOTCH2 COL1A1

3.36e-0596346HP:0030310
HumanPhenoPapule

FBN1 INSR LRP1 LAMA3 FAS LDLR MVK COL1A1

5.07e-05209348HP:0200034
HumanPhenoAbnormal atrioventricular valve morphology

CRELD1 FLNC KMT2D FBN1 FBN2 FAS LDLR NOTCH1 NOTCH2 COL1A1

6.09e-053503410HP:0006705
HumanPhenoAbnormality of the elbow

JAG2 FLNB FBN1 FBN2 AFF3 LAMA2 NOTCH2 COL1A1 LARGE1

6.61e-05282349HP:0009811
HumanPhenoAbnormal upper to lower segment ratio

FBN1 FBN2

1.29e-043342HP:0012772
HumanPhenoAbnormality of the calf

PAPPA2 FLNB FLNC FBN1 FBN2 AFF3 LAMA2 NOTCH2 COL1A1 LARGE1

1.34e-043843410HP:0002981
HumanPhenoPlatybasia

FLNB NOTCH2 COL1A1

1.73e-0417343HP:0002691
HumanPhenoAbnormal anterior eye segment morphology

CRELD1 VLDLR FLNB EYS KMT2D FBN1 FBN2 INSR LAMA3 CHD6 FAS NOTCH2NLC LDLR NOTCH1 NOTCH2 MVK CRB1 RHO COL1A1 LARGE1

1.99e-0414503420HP:0004328
HumanPhenoAbnormal knee physiology

FLNB FLNC FBN1 FBN2 COL1A1

2.44e-0487345HP:0034670
HumanPhenoIncisional hernia

FBN1 COL1A1

2.57e-044342HP:0004872
HumanPhenoNail dysplasia

FLNB KMT2D TMPRSS6 INSR LAMA3 NOTCH1 NOTCH2 MVK

2.61e-04264348HP:0002164
HumanPhenoLocalized skin lesion

CRELD1 FLNB KMT2D FBN1 INSR AFF3 LRP1 LAMA3 CHD6 FAS LDLR NOTCH1 NOTCH2 MVK COL1A1

2.86e-048973415HP:0011355
HumanPhenoAplasia/Hypoplasia of the skin

FBN1 LRP1 LAMA3 CHD6 NOTCH1 MVK COL1A1

2.91e-04201347HP:0008065
MousePhenoabnormal pelvic girdle bone morphology

PAPPA2 PCSK5 FBN1 FBN2 AFF3 COL1A1 TG

1.47e-0787657MP:0004509
MousePhenoabnormal craniofacial morphology

JAG2 PAPPA2 PCSK5 CRELD1 FLNB SCUBE1 KMT2D FBN1 FBN2 DSG3 CGRRF1 AFF3 LRP1 LAMA2 LAMA3 ITGA4 ITGB8 NOTCH1 TFPI SORL1 COL1A1

5.10e-0713726521MP:0000428
MousePhenocraniofacial phenotype

JAG2 PAPPA2 PCSK5 CRELD1 FLNB SCUBE1 KMT2D FBN1 FBN2 DSG3 CGRRF1 AFF3 LRP1 LAMA2 LAMA3 ITGA4 ITGB8 NOTCH1 TFPI SORL1 COL1A1

5.10e-0713726521MP:0005382
MousePhenoabnormal blood vessel morphology

PCSK5 CRELD1 VLDLR FLNB FLNC MFGE8 THBS1 NPR1 FBN1 ADAM9 UBR4 FAS LDLR ITGB8 NOTCH1 NOTCH2 CRB1 RHO BRAP COL1A1

6.64e-0614726520MP:0001614
MousePhenoaortic dissection

NPR1 FBN1 COL1A1

7.90e-069653MP:0004044
MousePhenoabnormal tibia morphology

PAPPA2 PCSK5 FLNB FBN1 FBN2 TMPRSS6 AFF3 NOTCH2 COL1A1 TG

8.23e-063756510MP:0000558
MousePhenoabnormal hindlimb zeugopod morphology

PAPPA2 PCSK5 FLNB FBN1 FBN2 TMPRSS6 AFF3 NOTCH2 COL1A1 TG

9.46e-063816510MP:0003857
MousePhenoabnormal hindlimb morphology

PAPPA2 PCSK5 FLNB FLNC THBS1 FBN1 FBN2 TMPRSS6 AFF3 NOTCH2 COL1A1 TG

1.16e-055766512MP:0000556
MousePhenoembryonic lethality during organogenesis

CRELD1 FLNB RIF1 KMT2D FBN1 UBR4 LRP1 ITGA4 ITGB8 NOTCH1 NOTCH2 BRAP TFPI COL1A1

3.94e-058766514MP:0006207
MousePhenoabnormal ulna morphology

PAPPA2 FLNB FBN1 FBN2 COL1A1

4.32e-0584655MP:0005108
MousePhenohemorrhage

PCSK5 THBS1 FBN1 LRP1 ITGA4 FAS ITGB8 NOTCH1 NOTCH2 BRAP TFPI COL1A1

4.75e-056646512MP:0001914
MousePhenoabnormal limb long bone morphology

JAG2 PAPPA2 PCSK5 FLNB FBN1 FBN2 TMPRSS6 AFF3 NOTCH2 COL1A1 TG

5.51e-055686511MP:0011504
MousePhenoabnormal vertebral column morphology

JAG2 PAPPA2 PCSK5 FLNB THBS1 FBN1 FBN2 DSG3 AFF3 LAMA2 NOTCH1 NOTCH2 COL1A1

5.57e-057876513MP:0004703
MousePhenoabnormal joint mobility

FLNB LAMA2 COL1A1

6.23e-0517653MP:0008069
MousePhenointernal hemorrhage

THBS1 FBN1 LRP1 ITGA4 FAS ITGB8 NOTCH1 TFPI COL1A1

7.06e-05387659MP:0001634
MousePhenoabnormal limb bone morphology

JAG2 PAPPA2 PCSK5 FLNB FBN1 FBN2 TMPRSS6 AFF3 NOTCH2 COL1A1 TG

7.40e-055876511MP:0002115
MousePhenoabnormal cranium morphology

JAG2 PAPPA2 FLNB SCUBE1 KMT2D FBN1 FBN2 CGRRF1 AFF3 LAMA2 LAMA3 TFPI COL1A1

7.76e-058136513MP:0000438
MousePhenoabnormal axial skeleton morphology

JAG2 PAPPA2 PCSK5 FLNB THBS1 SCUBE1 KMT2D FBN1 FBN2 DSG3 CGRRF1 AFF3 LAMA2 LAMA3 NOTCH1 NOTCH2 TFPI COL1A1

7.96e-0514586518MP:0002114
MousePhenoabnormal blood vessel physiology

VLDLR NPR1 FBN1 FBN2 ADAM9 FAS NOTCH1 CRB1 SORL1

8.11e-05394659MP:0000249
MousePhenoabnormal fibula morphology

PCSK5 FBN2 AFF3 COL1A1

9.03e-0551654MP:0002187
MousePhenoabnormal craniofacial bone morphology

JAG2 PAPPA2 FLNB SCUBE1 KMT2D FBN1 FBN2 CGRRF1 AFF3 LAMA2 LAMA3 TFPI COL1A1

9.23e-058276513MP:0002116
MousePhenoabnormal vasculature physiology

VLDLR NPR1 FBN1 FBN2 ADAM9 FAS NOTCH1 CRB1 SORL1

9.82e-05404659MP:0031170
MousePhenoabnormal extracellular matrix morphology

FLNB NPR1 LAMA2 ITGB8 COL1A1

9.96e-05100655MP:0013258
MousePhenoabnormal forelimb zeugopod morphology

PAPPA2 FLNB FBN1 FBN2 COL1A1

1.09e-04102655MP:0003855
MousePhenoabnormal blood circulation

PCSK5 THBS1 NPR1 FBN1 LRP1 ITGA4 FAS ITGB8 NOTCH1 NOTCH2 BRAP TFPI COL1A1

1.15e-048456513MP:0002128
MousePhenopathological neovascularization

VLDLR FBN2 ADAM9 NOTCH1 CRB1

1.43e-04108655MP:0003711
MousePhenodecreased diameter of long bones

FLNB NOTCH2 COL1A1

1.59e-0423653MP:0008150
MousePhenoabnormal T cell morphology

JAG2 THBS1 FBN1 P2RX5 DSG3 CGRRF1 TMPRSS6 LAMA2 ITGA4 ITGAD FAS NOTCH1 TG

1.68e-048786513MP:0008037
MousePhenoabnormal forelimb morphology

PAPPA2 PCSK5 FLNB FBN1 FBN2 COL1A1

1.96e-04182656MP:0000550
MousePhenoabnormal limb morphology

JAG2 PAPPA2 PCSK5 FLNB FLNC THBS1 FBN1 FBN2 TMPRSS6 AFF3 LRP1 NOTCH2 COL1A1 TG

2.18e-0410286514MP:0002109
MousePhenoabnormal extracutaneous pigmentation

VLDLR ADAM9 FAS LDLR CRB1 RHO

2.20e-04186656MP:0009389
MousePhenoabnormal long bone morphology

JAG2 PAPPA2 PCSK5 FLNB FBN1 FBN2 TMPRSS6 AFF3 NOTCH2 COL1A1 TG

2.56e-046766511MP:0003723
MousePhenokyphoscoliosis

FLNB LAMA2 COL1A1

2.59e-0427653MP:0000069
MousePhenoabnormal cutaneous collagen fibril morphology

FBN1 P3H4 COL1A1

2.59e-0427653MP:0008438
MousePhenodecreased T cell number

JAG2 THBS1 P2RX5 DSG3 TMPRSS6 LAMA2 ITGA4 ITGAD FAS NOTCH1

2.63e-045666510MP:0005018
MousePhenoabnormal pulmonary circulation

THBS1 NPR1 FBN1 COL1A1

2.93e-0469654MP:0002295
MousePhenojoint contracture

LAMA2 COL1A1

3.16e-046652MP:0030798
MousePhenoabnormal T cell number

JAG2 THBS1 P2RX5 DSG3 CGRRF1 TMPRSS6 LAMA2 ITGA4 ITGAD FAS NOTCH1 TG

3.39e-048186512MP:0006387
MousePhenoabnormal viscerocranium morphology

JAG2 PAPPA2 FLNB SCUBE1 KMT2D FBN1 FBN2 AFF3 LAMA3 COL1A1

3.81e-045936510MP:0005274
MousePhenoabnormal thymus lobule morphology

JAG2 PCSK5 LAMA2 FAS

4.04e-0475654MP:0002367
MousePhenoabnormal retina pigment epithelium morphology

VLDLR ADAM9 LDLR CRB1 RHO

4.05e-04135655MP:0005201
MousePhenoabnormal phalanx morphology

JAG2 FLNB FBN1 FBN2

4.25e-0476654MP:0005306
MousePhenoabnormal skin tensile strength

FBN1 P3H4 COL1A1

4.32e-0432653MP:0005275
MousePhenoshort vertebral body

NOTCH2 COL1A1

4.40e-047652MP:0004706
MousePhenoabnormal conjunctival epithelium morphology

THBS1 FAS

4.40e-047652MP:0004481
MousePhenoabnormal femur morphology

PAPPA2 PCSK5 FBN2 NOTCH2 COL1A1 TG

4.67e-04214656MP:0000559
MousePhenoabnormal hindlimb stylopod morphology

PAPPA2 PCSK5 FBN2 NOTCH2 COL1A1 TG

4.79e-04215656MP:0003856
MousePhenoabnormal joint morphology

FLNB FBN2 DSG3 AFF3 LAMA2 FAS TFPI COL1A1

4.83e-04397658MP:0002932
MousePhenoabnormal respiratory function

JAG2 FLNB FBN1 DSG3 LAMA2 LAMA3 FAS COL1A1

5.00e-04399658MP:0002327
MousePhenolimbs/digits/tail phenotype

JAG2 PAPPA2 PCSK5 FLNB FLNC THBS1 FBN1 FBN2 TMPRSS6 AFF3 LRP1 NOTCH2 TFPI COL1A1 TG

5.27e-0412586515MP:0005371
MousePhenodecreased lymphocyte cell number

JAG2 THBS1 FBN1 P2RX5 DSG3 TMPRSS6 LAMA2 ITGA4 ITGAD FAS NOTCH1 NOTCH2 TG

5.51e-049926513MP:0005016
MousePhenoaneurysm

FBN1 NOTCH2 COL1A1

5.65e-0435653MP:0003279
MousePhenoabnormal radius morphology

PAPPA2 FLNB FBN1 FBN2

5.67e-0482654MP:0000552
MousePhenodecreased length of long bones

PAPPA2 FLNB FBN1 TMPRSS6 AFF3 NOTCH2 COL1A1 TG

5.88e-04409658MP:0004686
MousePhenodecreased compact bone thickness

FLNB P3H4 NOTCH2 COL1A1

5.94e-0483654MP:0000135
MousePhenoabnormal pericardium morphology

FBN1 ITGA4 ITGB8 NOTCH1 NOTCH2 TFPI

6.09e-04225656MP:0000288
MousePhenoabnormal carpal bone morphology

FLNB FBN2 COL1A1

6.14e-0436653MP:0000554
MousePhenoabnormal skin condition

THBS1 FBN1 FAS LDLR NOTCH2 COL1A1

6.38e-04227656MP:0001191
MousePhenoretina neovascularization

VLDLR ADAM9 CRB1

7.21e-0438653MP:0008852
MousePhenoabnormal digit morphology

JAG2 PCSK5 FLNB FBN1 FBN2 AFF3 COL1A1

7.27e-04323657MP:0002110
MousePhenothin ribs

FLNB COL1A1

7.50e-049652MP:0004674
MousePhenoabnormal bone collagen fibril morphology

P3H4 COL1A1

7.50e-049652MP:0011642
MousePhenoabnormal aorta tunica adventitia morphology

FBN1 COL1A1

7.50e-049652MP:0009871
MousePhenoabnormal respiratory system physiology

JAG2 PCSK5 FLNB FLNC THBS1 NPR1 FBN1 DSG3 LAMA2 LAMA3 FAS COL1A1

7.74e-048976512MP:0002133
MousePhenoshort radius

PAPPA2 FLNB FBN1

8.38e-0440653MP:0004355
MousePhenodecreased radius size

PAPPA2 FLNB FBN1

8.38e-0440653MP:0030886
MousePhenoabnormal vascular development

PCSK5 CRELD1 FLNB FLNC MFGE8 THBS1 UBR4 ITGB8 NOTCH1

8.54e-04542659MP:0000259
MousePhenoabnormal vertebrae morphology

JAG2 PCSK5 FLNB FBN1 FBN2 AFF3 NOTCH1 NOTCH2 COL1A1

9.00e-04546659MP:0000137
MousePhenosyndactyly

JAG2 PCSK5 FBN2 COL1A1

9.12e-0493654MP:0000564
MousePhenoabnormal capillary morphology

FAS LDLR ITGB8 NOTCH2

9.12e-0493654MP:0003658
MousePhenoliver hyperplasia

FAS COL1A1

9.35e-0410652MP:0005141
MousePhenophotosensitivity

CRB1 RHO

9.35e-0410652MP:0001999
MousePhenoabnormal artery morphology

PCSK5 FLNB NPR1 FBN1 FAS LDLR NOTCH1 COL1A1

9.47e-04440658MP:0002191
MousePhenofocal hair loss

DSG3 TMPRSS6 COL1A1

1.04e-0343653MP:0000418
MousePhenoincreased spleen weight

PAPPA2 MFGE8 FBN1 TMPRSS6 ITGAD FAS

1.14e-03254656MP:0004952
MousePhenodecreased bone volume

FBN1 P3H4 NOTCH2 COL1A1

1.19e-03100654MP:0010876
MousePhenodecreased body fat mass

KMT2D FBN1 TG

1.26e-0346653MP:0014143
MousePhenoabnormal retina pigmentation

VLDLR CRB1 RHO

1.34e-0347653MP:0005103
MousePhenoincreased mast cell number

FBN1 DSG3

1.36e-0312652MP:0000324
MousePhenoabnormal eye pigmentation

VLDLR ADAM9 LDLR CRB1 RHO

1.45e-03179655MP:0001324
MousePhenoembryonic lethality during organogenesis, incomplete penetrance

FLNB RIF1 FBN1 ITGA4 ITGB8 TFPI

1.50e-03268656MP:0011108
MousePhenoabnormal muscle morphology

FLNC THBS1 NPR1 FBN1 FBN2 INSR LRP1 LAMA2 FAS P3H4 NOTCH1 NOTCH2 COL1A1

1.51e-0311066513MP:0002108
MousePhenoabnormal conjunctiva morphology

THBS1 FAS

1.61e-0313652MP:0001310
MousePhenotachypnea

FLNB LAMA2

1.61e-0313652MP:0005426
MousePhenoshort tibia

PAPPA2 FLNB FBN1 TMPRSS6 NOTCH2 TG

1.68e-03274656MP:0002764
MousePhenoabnormal respiration

JAG2 FLNB FLNC FBN1 DSG3 LAMA2 LAMA3 FAS COL1A1

1.70e-03598659MP:0001943
MousePhenopericardial effusion

FBN1 ITGB8 NOTCH2 TFPI

1.76e-03111654MP:0005312
MousePhenolung hemorrhage

THBS1 FBN1 COL1A1

1.80e-0352653MP:0001182
MousePhenothick skin

FBN1 LDLR COL1A1

1.80e-0352653MP:0001200
MousePhenoabnormal eye physiology

VLDLR THBS1 DSG3 ADAM9 MTMR3 FAS CRB1 RHO COL1A1

1.86e-03606659MP:0005253
MousePhenothin placenta labyrinth

UBR4 ITGB8

1.87e-0314652MP:0011523
MousePhenofused carpal bones

FLNB COL1A1

1.87e-0314652MP:0008915
MousePhenoabnormal kidney apoptosis

THBS1 FAS NOTCH2

1.90e-0353653MP:0011367
DomainEGF

JAG2 PCSK5 CRELD1 VLDLR FBLN7 MFGE8 THBS1 EYS SCUBE1 FBN1 FBN2 ADAM9 WIF1 NOTCH2NLA LRP1 LAMA2 LAMA3 NOTCH2NLC LDLR ITGB8 NOTCH1 NOTCH2 CRB1 SORL1

3.51e-282357224SM00181
DomainEGF-like_dom

JAG2 PCSK5 CRELD1 VLDLR FBLN7 MFGE8 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 ADAM9 WIF1 NOTCH2NLA LRP1 LAMA2 LAMA3 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1 SORL1

1.46e-272497224IPR000742
DomainEGF-like_CS

JAG2 CRELD1 VLDLR FBLN7 MFGE8 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 ADAM9 WIF1 NOTCH2NLA LRP1 LAMA2 LAMA3 NOTCH2NLC LDLR ITGB8 NOTCH1 NOTCH2 CRB1 SORL1

4.62e-272617224IPR013032
DomainEGF_2

JAG2 CRELD1 VLDLR FBLN7 MFGE8 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 ADAM9 WIF1 NOTCH2NLA LRP1 LAMA2 LAMA3 NOTCH2NLC LDLR ITGB8 NOTCH1 NOTCH2 CRB1 SORL1

6.71e-272657224PS01186
DomainEGF_1

JAG2 CRELD1 VLDLR FBLN7 MFGE8 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 ADAM9 WIF1 NOTCH2NLA LRP1 LAMA2 LAMA3 NOTCH2NLC LDLR ITGB8 NOTCH1 NOTCH2 CRB1

1.02e-252557223PS00022
DomainEGF_3

JAG2 CRELD1 VLDLR FBLN7 MFGE8 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 ADAM9 WIF1 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1 SORL1

2.21e-232357221PS50026
DomainEGF_CA

JAG2 CRELD1 VLDLR FBLN7 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1

2.27e-221227217SM00179
DomainEGF_Ca-bd_CS

JAG2 CRELD1 VLDLR FBLN7 EYS SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1

2.49e-22977216IPR018097
DomainEGF-like_Ca-bd_dom

JAG2 CRELD1 VLDLR FBLN7 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1

3.04e-221247217IPR001881
DomainEGF_CA

JAG2 CRELD1 VLDLR FBLN7 EYS SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1

3.53e-22997216PS01187
DomainASX_HYDROXYL

JAG2 CRELD1 VLDLR FBLN7 EYS SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1

4.19e-221007216PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 CRELD1 VLDLR FBLN7 EYS SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2 CRB1

1.13e-211067216IPR000152
DomainEGF_CA

JAG2 CRELD1 VLDLR FBLN7 THBS1 SCUBE1 FBN1 FBN2 HMCN2 NOTCH2NLA LRP1 NOTCH2NLC LDLR NOTCH1 NOTCH2

2.30e-21867215PF07645
DomainGrowth_fac_rcpt_

JAG2 EPHB6 PCSK5 CRELD1 VLDLR EYS SCUBE1 FBN1 FBN2 HMCN2 INSR LRP1 LAMA3 LDLR NOTCH1 NOTCH2 CRB1

1.76e-201567217IPR009030
DomainEGF

JAG2 VLDLR FBLN7 MFGE8 EYS WIF1 NOTCH2NLA LRP1 NOTCH2NLC NOTCH1 NOTCH2 CRB1

5.68e-141267212PF00008
DomainhEGF

JAG2 EYS FBN2 WIF1 NOTCH1 NOTCH2 CRB1

1.04e-1128727PF12661
DomainLdl_recept_b

VLDLR LRP1 LDLR SORL1

1.97e-0714724PF00058
DomainLDLRB

VLDLR LRP1 LDLR SORL1

1.97e-0714724PS51120
DomainLY

VLDLR LRP1 LDLR SORL1

2.68e-0715724SM00135
DomainLDLR_classB_rpt

VLDLR LRP1 LDLR SORL1

2.68e-0715724IPR000033
DomainLdl_recept_a

VLDLR TMPRSS6 LRP1 LDLR SORL1

8.01e-0745725PF00057
Domain-

VLDLR TMPRSS6 LRP1 LDLR SORL1

8.96e-07467254.10.400.10
DomainLDLRA_1

VLDLR TMPRSS6 LRP1 LDLR SORL1

1.11e-0648725PS01209
DomainLDLRA_2

VLDLR TMPRSS6 LRP1 LDLR SORL1

1.24e-0649725PS50068
DomainLDrepeatLR_classA_rpt

VLDLR TMPRSS6 LRP1 LDLR SORL1

1.24e-0649725IPR002172
DomainLDLa

VLDLR TMPRSS6 LRP1 LDLR SORL1

1.24e-0649725SM00192
Domain-

PAPPA2 THBS1 EYS LAMA2 LAMA3 CRB1

1.76e-06957262.60.120.200
DomainNotch_dom

PAPPA2 NOTCH1 NOTCH2

1.90e-067723IPR000800
DomainNotch

PAPPA2 NOTCH1 NOTCH2

1.90e-067723PF00066
DomainNL

PAPPA2 NOTCH1 NOTCH2

1.90e-067723SM00004
DomainEphrin_rec_like

EPHB6 PCSK5 SCUBE1 TG

2.42e-0625724SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHB6 PCSK5 SCUBE1 TG

2.42e-0625724IPR011641
DomaincEGF

SCUBE1 FBN1 FBN2 LRP1

2.85e-0626724IPR026823
DomaincEGF

SCUBE1 FBN1 FBN2 LRP1

2.85e-0626724PF12662
DomainLaminin_G

THBS1 EYS LAMA2 LAMA3 CRB1

2.89e-0658725IPR001791
DomainEGF_extracell

JAG2 ADAM9 WIF1 ITGB8 NOTCH1

3.42e-0660725IPR013111
DomainEGF_2

JAG2 ADAM9 WIF1 ITGB8 NOTCH1

3.42e-0660725PF07974
DomainEphrin_rec_like

EPHB6 SCUBE1 TG

8.87e-0611723PF07699
DomainLAM_G_DOMAIN

EYS LAMA2 LAMA3 CRB1

1.36e-0538724PS50025
Domain-

VLDLR LRP1 LDLR SORL1

1.51e-05397242.120.10.30
DomainLDLR_class-A_CS

VLDLR LRP1 LDLR SORL1

1.67e-0540724IPR023415
DomainLaminin_G_2

EYS LAMA2 LAMA3 CRB1

1.67e-0540724PF02210
DomainLamG

EYS LAMA2 LAMA3 CRB1

2.45e-0544724SM00282
Domain6-blade_b-propeller_TolB-like

VLDLR LRP1 LDLR SORL1

2.93e-0546724IPR011042
DomainFurin_repeat

PCSK5 CRELD1 INSR

4.30e-0518723IPR006212
DomainFU

PCSK5 CRELD1 INSR

4.30e-0518723SM00261
DomainDUF3454

NOTCH1 NOTCH2

4.39e-053722PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2

4.39e-053722IPR024600
DomainDUF3454

NOTCH1 NOTCH2

4.39e-053722SM01334
DomainFBN

FBN1 FBN2

4.39e-053722IPR011398
DomainNotch

NOTCH1 NOTCH2

8.75e-054722IPR008297
DomainNODP

NOTCH1 NOTCH2

8.75e-054722PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2

8.75e-054722IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2

8.75e-054722IPR010660
DomainNOD

NOTCH1 NOTCH2

8.75e-054722PF06816
DomainNOD

NOTCH1 NOTCH2

8.75e-054722SM01338
DomainNODP

NOTCH1 NOTCH2

8.75e-054722SM01339
DomainIntegrin_dom

ITGA4 ITGAD ITGB8

1.19e-0425723IPR032695
DomainLaminin_aI

LAMA2 LAMA3

1.45e-045722IPR009254
DomainLaminin_I

LAMA2 LAMA3

1.45e-045722PF06008
DomainLaminin_II

LAMA2 LAMA3

1.45e-045722PF06009
DomainLaminin_domII

LAMA2 LAMA3

1.45e-045722IPR010307
DomainLNR

NOTCH1 NOTCH2

1.45e-045722PS50258
Domain-

EPHB6 PCSK5 MFGE8 LAMA2

1.81e-04737242.60.120.260
DomainConA-like_dom

PAPPA2 THBS1 EYS LAMA2 LAMA3 CRB1

1.99e-04219726IPR013320
DomainTB

FBN1 FBN2

3.04e-047722PF00683
DomainLaminin_EGF

CRELD1 LAMA2 LAMA3

3.29e-0435723PF00053
DomainVWFC_1

JAG2 THBS1 COL1A1

3.58e-0436723PS01208
DomainLAMININ_IVA

LAMA2 LAMA3

4.04e-048722PS51115
DomainLaminin_B

LAMA2 LAMA3

4.04e-048722PF00052
Domain-

FBN1 FBN2

4.04e-0487223.90.290.10
DomainLamB

LAMA2 LAMA3

4.04e-048722SM00281
DomainLaminin_IV

LAMA2 LAMA3

4.04e-048722IPR000034
DomainVWC

JAG2 THBS1 COL1A1

4.21e-0438723SM00214
DomainVWFC_2

JAG2 THBS1 COL1A1

4.21e-0438723PS50184
DomainLaminin_EGF

CRELD1 LAMA2 LAMA3

4.21e-0438723IPR002049
DomainGalactose-bd-like

EPHB6 PCSK5 MFGE8 LAMA2

4.76e-0494724IPR008979
DomainTB

FBN1 FBN2

5.18e-049722PS51364
DomainTB_dom

FBN1 FBN2

5.18e-049722IPR017878
DomainVWF_dom

JAG2 THBS1 COL1A1

5.66e-0442723IPR001007
DomainIG_FLMN

FLNB FLNC

6.46e-0410722SM00557
DomainFN3

EPHB6 PAPPA2 FLNC INSR SORL1

7.39e-04185725SM00060
DomainFilamin

FLNB FLNC

7.88e-0411722PF00630
DomainIntegrin_alpha

ITGA4 ITGAD

7.88e-0411722PF00357
DomainFILAMIN_REPEAT

FLNB FLNC

7.88e-0411722PS50194
DomainLaminin_G_1

EYS LAMA2

7.88e-0411722PF00054
DomainFilamin/ABP280_rpt

FLNB FLNC

7.88e-0411722IPR001298
DomainFilamin/ABP280_repeat-like

FLNB FLNC

7.88e-0411722IPR017868
DomainSushi

PAPPA2 FBLN7 APOH

1.06e-0352723PF00084
DomainCCP

PAPPA2 FBLN7 APOH

1.18e-0354723SM00032
DomainFN3_dom

EPHB6 PAPPA2 FLNC INSR SORL1

1.27e-03209725IPR003961
DomainSUSHI

PAPPA2 FBLN7 APOH

1.32e-0356723PS50923
DomainSushi_SCR_CCP_dom

PAPPA2 FBLN7 APOH

1.38e-0357723IPR000436
DomainPkinase_Tyr

EPHB6 NPR1 INSR TEC

1.55e-03129724PF07714
DomainIntegrin_alpha_C_CS

ITGA4 ITGAD

1.70e-0316722IPR018184
DomainLaminin_N

LAMA2 LAMA3

1.70e-0316722IPR008211
DomainLAMININ_NTER

LAMA2 LAMA3

1.70e-0316722PS51117
DomainLaminin_N

LAMA2 LAMA3

1.70e-0316722PF00055
DomainLamNT

LAMA2 LAMA3

1.70e-0316722SM00136
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB6 NPR1 INSR TEC

1.99e-03138724IPR001245
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

THBS1 SCUBE1 FBN1 FBN2 ADAM9 TMPRSS6 LAMA2 LAMA3 ITGA4 ITGAD ITGB8 COL1A1

2.58e-093005812M610
PathwayPID_INTEGRIN1_PATHWAY

THBS1 FBN1 LAMA2 LAMA3 ITGA4 COL1A1

2.79e-0766586M18
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

THBS1 FBN1 ITGA4 ITGAD ITGB8 COL1A1

6.51e-0776586MM14867
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

THBS1 SCUBE1 FBN1 FBN2 TMPRSS6 ITGA4 ITGAD ITGB8 COL1A1

9.75e-07258589MM14572
PathwayKEGG_ECM_RECEPTOR_INTERACTION

THBS1 LAMA2 LAMA3 ITGA4 ITGB8 COL1A1

1.18e-0684586M7098
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

THBS1 FBN1 ITGA4 ITGAD ITGB8 COL1A1

1.27e-0685586M16441
PathwayWP_FOCAL_ADHESION

FLNB FLNC THBS1 LAMA2 LAMA3 ITGA4 ITGB8 COL1A1

1.43e-06199588M39402
PathwayKEGG_FOCAL_ADHESION

FLNB FLNC THBS1 LAMA2 LAMA3 ITGA4 ITGB8 COL1A1

1.43e-06199588M7253
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

SCUBE1 FBN1 FBN2 ADAM9 TMPRSS6 LAMA3 COL1A1

1.62e-06140587M587
PathwayWP_FOCAL_ADHESION

THBS1 LAMA2 LAMA3 ITGA4 ITGAD ITGB8 COL1A1

1.10e-05187587MM15913
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH2

1.84e-0513583M47423
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_3

VLDLR LRP1 LDLR

1.84e-0513583M42551
PathwayWP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING

THBS1 INSR LAMA2 LAMA3 ITGA4 ITGAD ITGB8 COL1A1

3.06e-05302588M39719
PathwayPID_INTEGRIN5_PATHWAY

FBN1 ITGA4 ITGB8

4.31e-0517583M212
PathwayWP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY

THBS1 INSR LAMA2 LAMA3 ITGA4 ITGAD ITGB8 COL1A1

5.26e-05326588MM15917
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_4

LRP1 FAS LDLR

9.63e-0522583M42574
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

THBS1 LAMA2 LAMA3 COL1A1

9.92e-0559584M27218
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

SCUBE1 FBN1 FBN2 TMPRSS6 COL1A1

1.03e-04114585MM14571
PathwayPID_INTEGRIN_CS_PATHWAY

ITGA4 ITGAD ITGB8

1.61e-0426583M47
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2

1.65e-045582M27411
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THBS1 NOTCH1 NOTCH2 LARGE1

1.73e-0468584M27303
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

JAG2 NOTCH1 NOTCH2

1.80e-0427583M39545
PathwayWP_CHOLESTEROL_METABOLISM

LRP1 APOH LDLR MVK

2.15e-0472584M46457
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2

2.47e-046582M27068
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA2 LAMA3 COL1A1

2.48e-0430583M27772
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 ITGB8

3.01e-0432583MM14854
PathwayPID_SYNDECAN_4_PATHWAY

THBS1 LAMA3 TFPI

3.01e-0432583M165
PathwayWP_MALE_INFERTILITY

THBS1 MOV10L1 INSR LTF FAS

3.18e-04145585M39856
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

JAG2 NOTCH1

3.45e-047582M27199
PathwayWP_PI3KAKT_SIGNALING

THBS1 INSR LAMA2 LAMA3 ITGA4 ITGB8 COL1A1

4.58e-04339587M39736
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FBN2 ITGB8

4.65e-0437583M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 ITGB8

5.44e-0439583MM14601
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA2 LAMA3 COL1A1

6.31e-0441583M27778
PathwayPID_INTEGRIN3_PATHWAY

THBS1 FBN1 COL1A1

7.26e-0443583M53
PathwayREACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH1

7.33e-0410582MM14849
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FBN2 ITGB8

7.77e-0444583M26969
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

ITGA4 ITGAD ITGB8 RHO

8.12e-04102584M39577
PathwayWP_INTEGRINMEDIATED_CELL_ADHESION

ITGA4 ITGAD ITGB8 RHO

8.12e-04102584MM15830
PathwayWP_NOTCH_SIGNALING_WP268

JAG2 NOTCH1 NOTCH2

8.30e-0445583M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH2

8.85e-0446583MM15971
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2

8.93e-0411582M47865
PathwayWP_NPHP1_DELETION_SYNDROME

FLNB FLNC

8.93e-0411582M48099
PathwayPID_INTEGRIN4_PATHWAY

LAMA2 LAMA3

8.93e-0411582M158
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH2

9.42e-0447583M7946
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

1.07e-0312582MM1562
PathwayBIOCARTA_HES_PATHWAY

NOTCH1 NOTCH2

1.07e-0312582M22042
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2

1.07e-0312582M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2

1.07e-0312582M47533
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH2

1.26e-0313582M47534
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

RIF1 NR2F6 NPR1 KMT2D INSR NOTCH1

1.44e-03301586MM15983
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

INSR ITGA4 ITGAD ITGB8

1.53e-03121584M39823
PathwayREACTOME_ANCHORING_FIBRIL_FORMATION

LAMA3 COL1A1

1.69e-0315582M27161
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_5

LRP1 LDLR

1.69e-0315582M42552
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

JAG2 NOTCH1

1.69e-0315582M27202
PathwayPID_NOTCH_PATHWAY

JAG2 NOTCH1 NOTCH2

1.82e-0359583M17
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1

1.92e-0316582M47424
PathwayWP_EBOLA_VIRUS_INFECTION_IN_HOST

FLNB FLNC MFGE8 ITGA4

1.94e-03129584M39693
PathwayWP_NOTCH_SIGNALING_WP61

JAG2 NOTCH1 NOTCH2

2.01e-0361583M39540
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

PCSK5 VLDLR LDLR

2.10e-0362583MM14686
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

JAG2 NOTCH1

2.17e-0317582M39389
PathwayREACTOME_COLLAGEN_DEGRADATION

ADAM9 TMPRSS6 COL1A1

2.30e-0364583M26953
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2

2.44e-0318582M614
PathwayWP_FAMILIAL_HYPERLIPIDEMIA_TYPE_1

LRP1 LDLR

2.44e-0318582M42559
PathwayREACTOME_SIGNALING_BY_NOTCH1

JAG2 NOTCH1

2.44e-0318582MM14775
PathwayWP_OVERVIEW_OF_NANOPARTICLE_EFFECTS

LAMA3 ITGAD

2.72e-0319582M39473
PathwayWP_STATIN_PATHWAY

LRP1 LDLR

2.72e-0319582MM15868
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

THBS1 NOTCH1 NOTCH2 LARGE1

2.82e-03143584M27275
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2

3.01e-0320582M27881
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

LAMA2 ITGA4 ITGB8

3.48e-0374583M16376
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

LAMA2 ITGA4 ITGB8

3.48e-0374583M39462
PathwayREACTOME_PLASMA_LIPOPROTEIN_ASSEMBLY_REMODELING_AND_CLEARANCE

PCSK5 VLDLR LDLR

3.62e-0375583M27032
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

JAG2 NOTCH2

3.65e-0322582M27210
PathwayREACTOME_ECM_PROTEOGLYCANS

LAMA2 LAMA3 COL1A1

3.76e-0376583M27219
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOGAP_RHOA_SIGNALING_PATHWAY

ITGA4 ITGB8

3.98e-0323582M47537
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_RHOGEF_RHOA_SIGNALING_PATHWAY

ITGA4 ITGB8

3.98e-0323582M47720
PathwayREACTOME_SIGNALING_BY_MET

LAMA2 LAMA3 COL1A1

4.19e-0379583M27643
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2

4.33e-0324582M11190
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

VLDLR LRP1 APOH LDLR MVK SORL1

4.64e-03381586M48063
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

JAG2 NOTCH1 NOTCH2

4.65e-0382583MM15922
PathwayPID_LYMPH_ANGIOGENESIS_PATHWAY

ITGA4 COL1A1

4.70e-0325582M274
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN1 FBN2

4.70e-0325582M39713
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

LAMA2 ITGA4 ITGB8

4.81e-0383583M8728
PathwayKEGG_MEDICUS_REFERENCE_ITGA_B_FAK_CDC42_SIGNALING_PATHWAY

ITGA4 ITGB8

5.07e-0326582M47719
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

RIF1 THBS1 FBN1 FBN2 MTMR3 LRP1 LAMA2 CRB1

3.78e-127177833541421
Pubmed

Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.

NOTCH2NLB NOTCH2NLA NOTCH2NLC NOTCH2

2.22e-11477432330268
Pubmed

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

NOTCH2NLB NOTCH2NLA NOTCH2NLC NOTCH2

1.11e-10577429856954
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

JAG2 CRELD1 THBS1 NPR1 FBN1 FBN2 P2RX5 ADAM9 LRP1 LDLR ITGB8 P3H4 NOTCH1 NOTCH2 TFPI SORL1 COL1A1

8.77e-101201771735696571
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

MFGE8 THBS1 FBN1 HMCN2 LAMA2 LAMA3 APOH COL1A1

1.31e-0914677827068509
Pubmed

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

VLDLR LRP1 LDLR SORL1

2.77e-09977420005821
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

VLDLR NPR1 INSR LRP1 LDLR NOTCH1 NOTCH2

2.87e-0910177723382219
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

PCSK5 MFGE8 THBS1 FBN1 ADAM9 LAMA2 LDLR TFPI COL1A1

4.36e-0924877924006456
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

CRELD1 THBS1 FBN1 FBN2 HMCN2 LAMA2 LAMA3 COL1A1

5.48e-0917577828071719
Pubmed

Recurrent mutations in NF-κB pathway components, KMT2D, and NOTCH1/2 in ocular adnexal MALT-type marginal zone lymphomas.

KMT2D NOTCH1 NOTCH2

1.04e-08377327566587
Pubmed

The hepatic uptake of VLDL in lrp-ldlr-/-vldlr-/- mice is regulated by LPL activity and involves proteoglycans and SR-BI.

VLDLR LRP1 LDLR

1.04e-08377318367731
Pubmed

Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.

JAG2 NOTCH1 NOTCH2

1.04e-08377318458347
Pubmed

The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model.

JAG2 NOTCH1 NOTCH2

1.04e-08377337330998
Pubmed

Discovery and refinement of loci associated with lipid levels.

VLDLR INSR MTMR3 LRP1 APOH LDLR MVK BRAP

2.36e-0821177824097068
Pubmed

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.

NOTCH2NLB NOTCH2NLA NOTCH2NLC

4.17e-08477329561261
Pubmed

Developmental regulation of LR11 expression in murine brain.

VLDLR LDLR SORL1

4.17e-0847739726247
Pubmed

The apoE isoform binding properties of the VLDL receptor reveal marked differences from LRP and the LDL receptor.

VLDLR LRP1 LDLR

4.17e-08477315863833
Pubmed

LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo.

VLDLR LRP1 LDLR

4.17e-08477315840700
Pubmed

Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse.

JAG2 NOTCH1 NOTCH2

4.17e-08477324398584
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

MFGE8 THBS1 FBN1 HMCN2 LAMA2 LAMA3 COL1A1

9.40e-0816777722159717
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

VLDLR LRP1 LDLR

1.04e-07577318685438
Pubmed

Cloning of a complementary deoxyribonucleic acid encoding the murine homolog of the very low density lipoprotein/apolipoprotein-E receptor: expression pattern and assignment of the gene to mouse chromosome 19.

VLDLR LRP1 LDLR

1.04e-0757738013374
Pubmed

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.

NOTCH2NLB NOTCH2NLA NOTCH2NLC

1.04e-07577329856955
Pubmed

Functional diversity of notch family genes in fetal lung development.

JAG2 NOTCH1 NOTCH2

1.04e-07577315064243
Pubmed

Critical Role of SREBP-1c Large-VLDL Pathway in Environment-Induced Hypertriglyceridemia of Apo AV Deficiency.

VLDLR LRP1 LDLR

1.04e-07577330700132
Pubmed

Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.

VLDLR LRP1 LDLR

1.04e-07577312746448
Pubmed

Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.

VLDLR LRP1 LDLR

1.04e-07577318992221
Pubmed

Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance.

VLDLR LRP1 LDLR

1.04e-07577323959870
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

KMT2D FBN1 FBN2 LRP1 LDLR NOTCH1 NOTCH2

1.82e-0718477732908313
Pubmed

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.

JAG2 NOTCH1 NOTCH2

2.08e-07677310958687
Pubmed

PCSK9 is not involved in the degradation of LDL receptors and BACE1 in the adult mouse brain.

PCSK5 VLDLR LDLR

2.08e-07677320453200
Pubmed

Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.

VLDLR NOTCH1 NOTCH2

2.08e-07677318957219
Pubmed

Apolipoprotein CI causes hypertriglyceridemia independent of the very-low-density lipoprotein receptor and apolipoprotein CIII in mice.

VLDLR LRP1 LDLR

2.08e-07677316478678
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

FAS NOTCH1 NOTCH2

2.08e-07677322615412
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 FBN2 LAMA3 COL1A1

3.20e-072677434189436
Pubmed

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.

JAG2 NOTCH1 NOTCH2

3.63e-07777310383933
Pubmed

Human ligands of the Notch receptor.

JAG2 NOTCH1 NOTCH2

3.63e-07777310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

JAG2 NOTCH1 NOTCH2

3.63e-07777312846471
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

VLDLR LRP1 LDLR

3.63e-07777312169628
Pubmed

Notch1 and 2 cooperate in limb ectoderm to receive an early Jagged2 signal regulating interdigital apoptosis.

JAG2 NOTCH1 NOTCH2

3.63e-07777316169548
Pubmed

A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice.

JAG2 NOTCH1 NOTCH2 COL1A1

3.75e-072777429956664
Pubmed

P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.

JAG2 NOTCH1 NOTCH2

5.80e-07877322652674
Pubmed

Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.

VLDLR LRP1 LDLR

5.80e-07877310380922
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

JAG2 NOTCH1 NOTCH2

5.80e-0787739858718
Pubmed

Notch/Delta expression in the developing mouse lung.

JAG2 NOTCH1 NOTCH2

5.80e-07877311044610
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

JAG2 FLNB WIF1 NOTCH2

5.82e-073077419054571
Pubmed

Functional proteomics mapping of a human signaling pathway.

PAPPA2 FLNB FLNC NPR1 KMT2D FBN2 UBR4 LRP1 CHD6 NOTCH2

7.35e-07591771015231748
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

EPHB6 VLDLR FLNB MFGE8 THBS1 FBN1 ADAM9 DNAJA2 UBR4 WIF1 MTMR3 LRP1 CHD6 ITGB8

7.86e-071285771435914814
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

JAG2 NOTCH1 NOTCH2

8.68e-07977311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

JAG2 NOTCH1 NOTCH2

8.68e-07977316245338
Pubmed

Targeted inactivation of the mouse alpha 2-macroglobulin gene.

VLDLR LRP1 LDLR

8.68e-0797737544347
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

JAG2 ITGA4 NOTCH1 NOTCH2

1.10e-063577421252157
Pubmed

The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.

JAG2 NOTCH1 NOTCH2 RHO

1.10e-063577428402857
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

JAG2 NOTCH1 NOTCH2

1.24e-061077323665443
Pubmed

Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.

FBN1 FBN2 COL1A1

1.24e-061077330738849
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

MFGE8 THBS1 FBN1 FBN2 COL1A1

1.41e-068677528327460
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH1 NOTCH2

1.70e-061177316607638
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

JAG2 NOTCH1 NOTCH2

1.70e-061177310878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

JAG2 NOTCH1 NOTCH2

1.70e-061177312866128
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

JAG2 NOTCH1 NOTCH2

2.26e-061277315465494
Pubmed

Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.

MFGE8 FBN1 LAMA2 APOH COL1A1

2.56e-069777527559042
Pubmed

Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.

JAG2 NOTCH1 NOTCH2

2.94e-061377331202705
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

JAG2 NOTCH1 NOTCH2

2.94e-061377311578869
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

MFGE8 THBS1 FBN1 APOH COL1A1

3.13e-0610177520551380
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

VLDLR LRP1 LDLR

3.73e-061477317389516
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

JAG2 NOTCH1 NOTCH2

3.73e-061477314757642
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

EPHB6 FBLN7 EYS INSR MTMR3 LRP1 CHD6 COL1A1

4.30e-0642077828065597
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

JAG2 NOTCH1 NOTCH2

4.66e-061577312971992
Pubmed

Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.

JAG2 NOTCH1 NOTCH2

4.66e-061577317194759
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

JAG2 NOTCH1 NOTCH2

4.66e-06157739291577
Pubmed

Lunatic fringe, FGF, and BMP regulate the Notch pathway during epithelial morphogenesis of teeth.

JAG2 NOTCH1 NOTCH2

4.66e-061577312167404
Pubmed

COUP-TFI controls Notch regulation of hair cell and support cell differentiation.

JAG2 NOTCH1 NOTCH2

4.66e-061577316914494
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

THBS1 FBN1 FBN2 COL1A1

4.73e-065077423658023
Pubmed

Homo- and heterotypic fibrillin-1 and -2 interactions constitute the basis for the assembly of microfibrils.

FBN1 FBN2

4.84e-06277212399449
Pubmed

Fibrillin-1 and fibrillin-2 are essential for formation of thick oxytalan fibers in human nonpigmented ciliary epithelial cells in vitro.

FBN1 FBN2

4.84e-06277221851253
Pubmed

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

INSR LDLR

4.84e-06277219273907
Pubmed

Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitecture.

NOTCH1 NOTCH2

4.84e-06277224508387
Pubmed

Notch controls generation and function of human effector CD8+ T cells.

NOTCH1 NOTCH2

4.84e-06277223380742
Pubmed

New Evidence Supporting the Role of FBN1 in the Development of Adolescent Idiopathic Scoliosis.

FBN1 FBN2

4.84e-06277230044367
Pubmed

Material and mechanical properties of bones deficient for fibrillin-1 or fibrillin-2 microfibrils.

FBN1 FBN2

4.84e-06277221440062
Pubmed

MAGP-2 has multiple binding regions on fibrillins and has covalent periodic association with fibrillin-containing microfibrils.

FBN1 FBN2

4.84e-06277215131124
Pubmed

A neuronal VLDLR variant lacking the third complement-type repeat exhibits high capacity binding of apoE containing lipoproteins.

VLDLR LDLR

4.84e-06277219393635
Pubmed

Low density lipoprotein receptor-related protein polymorphisms are not risk factors for venous thromboembolism.

LRP1 LDLR

4.84e-06277217889283
Pubmed

Differential Notch1 and Notch2 expression and frequent activation of Notch signaling in gastric cancers.

NOTCH1 NOTCH2

4.84e-06277221466361
Pubmed

Notch signaling regulates formation of the three-dimensional architecture of intrahepatic bile ducts in mice.

NOTCH1 NOTCH2

4.84e-06277220069650
Pubmed

Testosterone influenced the expression of Notch1, Notch2 and Jagged1 induced by lipopolysaccharide in macrophages.

NOTCH1 NOTCH2

4.84e-06277215625786
Pubmed

Microfibril structure masks fibrillin-2 in postnatal tissues.

FBN1 FBN2

4.84e-06277220404337
Pubmed

Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice.

LRP1 LDLR

4.84e-06277211971949
Pubmed

Fibrillln mutations in Marfan syndrome and related phenotypes.

FBN1 FBN2

4.84e-0627728791520
Pubmed

Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance.

LRP1 LTF

4.84e-0627721464627
Pubmed

Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturation.

NOTCH1 NOTCH2

4.84e-06277217261636
Pubmed

Motch A and motch B--two mouse Notch homologues coexpressed in a wide variety of tissues.

NOTCH1 NOTCH2

4.84e-0627728440332
Pubmed

[Expression and significance of Notch-1 and Jagged-2 in patients with Hirschsprung disease].

JAG2 NOTCH1

4.84e-06277222030773
Pubmed

Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18.

FBN1 FBN2

4.84e-0627728307578
Pubmed

Tissue factor pathway inhibitor binds to platelet thrombospondin-1.

THBS1 TFPI

4.84e-06277210922378
Pubmed

Internalization but not binding of thrombospondin-1 to low density lipoprotein receptor-related protein-1 requires heparan sulfate proteoglycans.

THBS1 LRP1

4.84e-06277214991768
Pubmed

Influence of fibrillin-1 genotype on aortic stiffness in men: a note of caution.

FBN1 COL1A1

4.84e-06277216540720
Pubmed

Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.

FBN1 FBN2

4.84e-0627727744963
Pubmed

Differential expression of Notch1 and Notch2 in developing and adult mouse brain.

NOTCH1 NOTCH2

4.84e-0627727609614
Pubmed

Notch dimerization and gene dosage are important for normal heart development, intestinal stem cell maintenance, and splenic marginal zone B-cell homeostasis during mite infestation.

NOTCH1 NOTCH2

4.84e-06277233017398
InteractionIGFL3 interactions

JAG2 PCSK5 VLDLR FBN2 ADAM9 INSR LAMA3 LDLR NOTCH1 NOTCH2 SORL1

2.61e-15757311int:IGFL3
InteractionNTN5 interactions

JAG2 FBN1 FBN2 LDLR NOTCH1 NOTCH2 SORL1

2.01e-1224737int:NTN5
InteractionST14 interactions

JAG2 PCSK5 VLDLR MFGE8 FBN1 FBN2 ADAM9 LAMA3 LDLR NOTCH2

3.72e-092077310int:ST14
InteractionLYZL1 interactions

JAG2 MFGE8 THBS1 ADAM9 INSR LDLR P3H4 SORL1

1.06e-08118738int:LYZL1
InteractionZDHHC15 interactions

RIF1 THBS1 FBN1 FBN2 MTMR3 LRP1 LAMA2 CRB1

1.68e-08125738int:ZDHHC15
InteractionTAFA2 interactions

INSR LAMA3 ITGA4 LDLR SORL1 LARGE1

1.75e-0847736int:TAFA2
InteractionCFC1 interactions

PCSK5 THBS1 ADAM9 UBR4 P3H4 NOTCH1 NOTCH2 SORL1

1.78e-08126738int:CFC1
InteractionWNT3A interactions

JAG2 INSR LRP1 LDLR NOTCH1 NOTCH2

2.26e-0849736int:WNT3A
InteractionFBXO2 interactions

JAG2 PCSK5 FBN1 FBN2 ADAM9 INSR LAMA3 ITGA4 NOTCH1 NOTCH2 BRAP SORL1

2.64e-084117312int:FBXO2
InteractionZNF408 interactions

CRELD1 VLDLR FBN1 FBN2 NOTCH2NLA LDLR NOTCH2 SORL1

5.36e-08145738int:ZNF408
InteractionZFP41 interactions

FBN1 FBN2 LRP1 LDLR NOTCH2 SORL1

5.74e-0857736int:ZFP41
InteractionPRG2 interactions

JAG2 PCSK5 THBS1 FBN2 ADAM9 LDLR P3H4 NOTCH1 NOTCH2 SORL1

7.74e-082857310int:PRG2
InteractionVEGFD interactions

MFGE8 ADAM9 UBR4 NOTCH1 SORL1

2.48e-0738735int:VEGFD
InteractionCCN6 interactions

LDLR NOTCH1 NOTCH2 SORL1

5.89e-0719734int:CCN6
InteractionSIRPD interactions

JAG2 THBS1 ADAM9 P3H4 NOTCH1 SORL1

6.85e-0786736int:SIRPD
InteractionSLURP1 interactions

PCSK5 MFGE8 INSR LAMA3 LDLR NOTCH2 SORL1

9.03e-07144737int:SLURP1
InteractionFOXD4L6 interactions

FBN2 LDLR NOTCH1 NOTCH2 SORL1

9.14e-0749735int:FOXD4L6
InteractionEDN3 interactions

JAG2 LDLR P3H4 NOTCH1 NOTCH2 SORL1

2.62e-06108736int:EDN3
InteractionFBN2 interactions

THBS1 FBN1 FBN2 INSR NOTCH2

3.78e-0665735int:FBN2
InteractionFURIN interactions

PCSK5 FLNC DSG3 UBR4 LRP1 PPA1 NOTCH1 SORL1

3.89e-06255738int:FURIN
InteractionITGB2 interactions

FLNB FLNC CGRRF1 UBR4 NOTCH2NLA ITGAD

8.37e-06132736int:ITGB2
InteractionCST9L interactions

PCSK5 ADAM9 NOTCH2NLA LAMA3 NOTCH1

9.33e-0678735int:CST9L
InteractionGREM2 interactions

FBN2 LDLR NOTCH2 SORL1

9.56e-0637734int:GREM2
InteractionMFAP2 interactions

JAG2 FBN1 FBN2

9.80e-0612733int:MFAP2
InteractionCD36 interactions

VLDLR THBS1 LDLR COL1A1

1.18e-0539734int:CD36
InteractionPI15 interactions

PCSK5 THBS1 LDLR P3H4 SORL1

1.26e-0583735int:PI15
InteractionJAG1 interactions

JAG2 THBS1 NOTCH1 NOTCH2

1.45e-0541734int:JAG1
InteractionIGSF5 interactions

LDLR NOTCH1 NOTCH2

1.61e-0514733int:IGSF5
InteractionF10 interactions

TMPRSS6 NOTCH2NLA APOH TFPI

1.76e-0543734int:F10
InteractionRLN1 interactions

INSR ITGA4 P3H4 SORL1 LARGE1

2.20e-0593735int:RLN1
InteractionCTSG interactions

THBS1 NOTCH2NLA LRP1 LDLR SORL1

2.44e-0595735int:CTSG
InteractionELANE interactions

THBS1 NOTCH2NLA LRP1 TFPI

2.51e-0547734int:ELANE
InteractionLGALS1 interactions

JAG2 THBS1 INSR ITGA4 LDLR NOTCH1 NOTCH2 SORL1

2.64e-05332738int:LGALS1
InteractionITGAV interactions

MFGE8 THBS1 ADAM9 INSR ITGA4 ITGB8

2.78e-05163736int:ITGAV
InteractionPRG3 interactions

PCSK5 FBN2 LDLR NOTCH2

2.97e-0549734int:PRG3
InteractionPATE1 interactions

JAG2 ADAM9 INSR SORL1

2.97e-0549734int:PATE1
InteractionAPOE interactions

VLDLR SCCPDH LRP1 APOH LDLR SORL1

3.64e-05171736int:APOE
InteractionMFAP5 interactions

JAG2 FBN1 FBN2 LDLR

3.76e-0552734int:MFAP5
InteractionDAB1 interactions

VLDLR LRP1 TRIM40 LDLR NOTCH1

4.33e-05107735int:DAB1
InteractionDEFB125 interactions

FBN2 UBR4 LAMA3

4.97e-0520733int:DEFB125
InteractionLYPD1 interactions

JAG2 PCSK5 ADAM9 NOTCH2

5.80e-0558734int:LYPD1
InteractionINSL5 interactions

PCSK5 ADAM9 UBR4 INSR

5.80e-0558734int:INSL5
InteractionWNT2 interactions

NOTCH1 NOTCH2 SORL1

7.67e-0523733int:WNT2
InteractionHRG interactions

THBS1 FBN1 FBN2 P3H4

8.03e-0563734int:HRG
InteractionTHBS1 interactions

THBS1 FBN2 LRP1 TFPI COL1A1

9.79e-05127735int:THBS1
InteractionLY86 interactions

JAG2 PCSK5 THBS1 ADAM9 INSR P3H4

1.36e-04217736int:LY86
InteractionSDF2L1 interactions

JAG2 PCSK5 MFGE8 ADAM9 INSR P3H4 SORL1

1.64e-04322737int:SDF2L1
InteractionDYRK1A interactions

VLDLR FLNC THBS1 KMT2D FBN1 ADAM9 WIF1 ITGB8 NOTCH2

1.66e-04552739int:DYRK1A
InteractionTAFA3 interactions

FBN2 INSR LDLR SORL1

1.85e-0478734int:TAFA3
InteractionCST9 interactions

UBR4 ITGA4

1.92e-046732int:CST9
InteractionEPPIN interactions

ADAM9 LTF

1.92e-046732int:EPPIN
InteractionCLEC2B interactions

JAG2 MFGE8 NOTCH1 NOTCH2 SORL1

1.94e-04147735int:CLEC2B
InteractionSNX17 interactions

VLDLR INSR LRP1 LDLR

2.13e-0481734int:SNX17
InteractionBTNL2 interactions

JAG2 MFGE8 ADAM9 INSR SORL1

2.49e-04155735int:BTNL2
InteractionZNF74 interactions

JAG2 NOTCH1 SORL1

2.52e-0434733int:ZNF74
InteractionDLK2 interactions

ADAM9 LDLR NOTCH1

2.99e-0436733int:DLK2
InteractionTIMP3 interactions

UBR4 LDLR NOTCH2 SORL1

3.20e-0490734int:TIMP3
InteractionWNT10A interactions

LDLR NOTCH1 NOTCH2

3.24e-0437733int:WNT10A
InteractionLTBP1 interactions

FBN1 FBN2 LAMA2 NOTCH2

3.48e-0492734int:LTBP1
InteractionITGB3 interactions

FLNB FLNC THBS1 UBR4 ITGA4

3.81e-04170735int:ITGB3
InteractionPTPRK interactions

PCSK5 ADAM9 INSR LAMA3 ITGA4

4.58e-04177735int:PTPRK
InteractionTIMP2 interactions

SETDB2 THBS1 FBN1 FBN2 LTF COL1A1

5.03e-04277736int:TIMP2
InteractionDCN interactions

THBS1 FBN1 COL1A1

5.07e-0443733int:DCN
InteractionCLEC12B interactions

JAG2 PCSK5 MFGE8 ADAM9 LARGE1

5.46e-04184735int:CLEC12B
InteractionFASLG interactions

NOTCH2NLA TEC FAS P3H4

5.75e-04105734int:FASLG
InteractionITGAD interactions

JAG2 VSIG8 ITGAD

6.19e-0446733int:ITGAD
InteractionCMA1 interactions

JAG2 LDLR SORL1

6.19e-0446733int:CMA1
InteractionICAM4 interactions

NOTCH2NLA ITGA4 SORL1

6.19e-0446733int:ICAM4
InteractionJAG2 interactions

JAG2 ITGAD NOTCH1 NOTCH2

6.85e-04110734int:JAG2
InteractionMFSD13A interactions

NOTCH2NLA COL1A1

6.97e-0411732int:MFSD13A
Cytoband12q24

MVK BRAP

8.12e-042577212q24
Cytoband22q12.3

TMPRSS6 LARGE1

1.42e-033377222q12.3
GeneFamilyLow density lipoprotein receptors

VLDLR LRP1 LDLR

5.25e-0613493634
GeneFamilyFibulins

FBLN7 HMCN2

1.99e-048492556
GeneFamilyLaminin subunits

LAMA2 LAMA3

4.67e-0412492626
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA2 FBLN7 APOH

4.94e-04574931179
GeneFamilyCD molecules|Integrin alpha subunits

ITGA4 ITGAD

1.07e-03184921160
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETDB2 KMT2D

3.82e-0334492487
GeneFamilyADAM metallopeptidase domain containing|CD molecules

INSR LRP1 ITGA4 ITGAD FAS

4.16e-03394495471
GeneFamilyRing finger proteins

CGRRF1 TRIM40 RNF17 BRAP

6.49e-0327549458
GeneFamilyFibronectin type III domain containing

EPHB6 INSR SORL1

9.30e-03160493555
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD1 FBLN7 MFGE8 THBS1 EYS FBN1 FBN2 HMCN2 LAMA2 LAMA3

1.56e-101967210M3008
CoexpressionNABA_CORE_MATRISOME

CRELD1 FBLN7 MFGE8 THBS1 EYS FBN1 FBN2 HMCN2 LAMA2 LAMA3 COL1A1

2.38e-102757211M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

CRELD1 FBLN7 MFGE8 THBS1 FBN1 FBN2 HMCN2 LAMA2 LAMA3

2.75e-09191729MM17059
CoexpressionNABA_CORE_MATRISOME

CRELD1 FBLN7 MFGE8 THBS1 FBN1 FBN2 HMCN2 LAMA2 LAMA3 COL1A1

3.48e-092707210MM17057
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

FLNC MFGE8 FBN1 FBN2 LRP1 ITGB8 P3H4 COL1A1

4.09e-09137728M40313
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

THBS1 FBN1 FBN2 LRP1 LAMA2 LAMA3 FAS NOTCH2 COL1A1

4.11e-09200729M5930
CoexpressionNABA_MATRISOME

PAPPA2 PCSK5 CRELD1 FBLN7 MFGE8 THBS1 EYS SCUBE1 FBN1 FBN2 HMCN2 ADAM9 WIF1 LAMA2 LAMA3 COL1A1

1.42e-0810267216M5889
CoexpressionNABA_MATRISOME

PAPPA2 PCSK5 CRELD1 FBLN7 MFGE8 THBS1 SCUBE1 FBN1 FBN2 HMCN2 ADAM9 WIF1 LAMA2 LAMA3 COL1A1

7.96e-0810087215MM17056
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

EPHB6 THBS1 NPR1 TMPRSS6 NOTCH1 NOTCH2

1.97e-06135726M5825
CoexpressionVERHAAK_AML_WITH_NPM1_MUTATED_DN

VLDLR FLNB SCCPDH P2RX5 LTF TFPI SORL1

5.74e-06250727M10117
CoexpressionKAYO_CALORIE_RESTRICTION_MUSCLE_UP

LRP1 LAMA2 FAS ITGB8 COL1A1

6.17e-0694725M7013
CoexpressionHU_FETAL_RETINA_FIBROBLAST

FLNB SCUBE1 FBN1 FBN2 P3H4 NOTCH2 TFPI COL1A1

1.06e-05385728M39264
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 NOTCH2

1.08e-0516723MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

JAG2 NOTCH1 NOTCH2

1.08e-0516723M2207
CoexpressionMURARO_PANCREAS_MESENCHYMAL_STROMAL_CELL

MFGE8 THBS1 FBN1 NOTCH2NLA LAMA2 P3H4 NOTCH1 NOTCH2 TFPI COL1A1

1.65e-056817210M39175
CoexpressionGSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP

NOTCH2NLA MTMR3 ITGA4 TET3 NOTCH2 SORL1

1.83e-05199726M4460
CoexpressionRODWELL_AGING_KIDNEY_NO_BLOOD_UP

PAPPA2 MFGE8 FBN1 LTF TFPI COL1A1

3.56e-05224726M9893
CoexpressionJEON_SMAD6_TARGETS_UP

THBS1 FBN1 FAS

3.86e-0524723M4592
CoexpressionHALLMARK_COAGULATION

THBS1 FBN1 ADAM9 TMPRSS6 LRP1

3.96e-05138725M5946
CoexpressionSESTO_RESPONSE_TO_UV_C8

FLNB FBN2 LAMA3 SORL1

4.42e-0571724M2948
CoexpressionHALLMARK_UV_RESPONSE_DN

VLDLR LDLR NOTCH2 TFPI COL1A1

4.86e-05144725M5942
CoexpressionBMI1_DN.V1_UP

VLDLR FLNB MFGE8 ITGA4 ITGB8

5.36e-05147725M2782
CoexpressionBOQUEST_STEM_CELL_UP

FBN1 NOTCH2NLA LRP1 LAMA2 NOTCH2 COL1A1

8.30e-05261726M1834
CoexpressionSNIJDERS_AMPLIFIED_IN_HEAD_AND_NECK_TUMORS

EYS ADAM9 LAMA3

1.44e-0437723M12802
CoexpressionVERRECCHIA_DELAYED_RESPONSE_TO_TGFB1

THBS1 ITGA4 ITGB8

1.44e-0437723M16643
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

FLNB SETDB2 DNAJA2 PPA1 FAS ITGB8 NOTCH1

1.51e-04418727M12676
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

VLDLR FLNB MFGE8 THBS1 LAMA2 P3H4 SORL1 COL1A1 LARGE1

1.55e-04721729M1999
CoexpressionDCA_UP.V1_DN

MFGE8 KMT2D NOTCH2NLA LAMA3 TG

1.58e-04185725M2760
CoexpressionCHICAS_RB1_TARGETS_CONFLUENT

MFGE8 THBS1 FBN1 FBN2 AFF3 ITGA4 NOTCH2 COL1A1

1.62e-04567728M2129
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

FLNC PDE8B ADAM9 LRP1 ITGB8 P3H4 NOTCH2 CRB1

1.76e-04574728M39056
CoexpressionFOSTER_TOLERANT_MACROPHAGE_DN

FLNB SETDB2 DNAJA2 PPA1 FAS ITGB8 NOTCH1

1.92e-04435727MM1221
CoexpressionSMID_BREAST_CANCER_LUMINAL_B_DN

MFGE8 P2RX5 DSG3 WIF1 LTF FAS TET3 TFPI

2.05e-04587728M17572
CoexpressionBRUNEAU_HEART_GREAT_VESSELS_AND_VALVULOGENESIS

NOTCH1 NOTCH2

2.06e-048722M9884
CoexpressionGSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_DN

CRELD1 THBS1 KMT2D FAS LARGE1

2.07e-04196725M9590
CoexpressionGSE19512_NAUTRAL_VS_INDUCED_TREG_UP

PCSK5 NR2F6 KMT2D P2RX5 MVK

2.12e-04197725M8361
CoexpressionGSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_UP

EPHB6 NR2F6 LAMA3 MVK TFPI

2.17e-04198725M8370
CoexpressionGSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP

PCSK5 FLNB AFF3 ZNF763 TET3

2.17e-04198725M3104
CoexpressionGSE42021_TREG_VS_TCONV_PLN_DN

JAG2 CRELD1 VLDLR FBN2 NOTCH2NLA

2.22e-04199725M9574
CoexpressionGSE3982_EOSINOPHIL_VS_BCELL_UP

INSR WIF1 MTMR3 NOTCH1 NOTCH2

2.22e-04199725M5406
CoexpressionHALLMARK_P53_PATHWAY

JAG2 CGRRF1 RRP8 FAS NOTCH1

2.27e-04200725M5939
CoexpressionGSE29618_MONOCYTE_VS_MDC_UP

FBN2 LRP1 LDLR NOTCH2 SORL1

2.27e-04200725M4948
CoexpressionGSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP

CASP8AP2 P2RX5 PDE8B NOTCH2 SORL1

2.27e-04200725M4449
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2A

FLNC MFGE8 LRP1 ITGB8 P3H4 NOTCH1 NOTCH2 CRB1

2.38e-04600728M39055
CoexpressionZHAN_MULTIPLE_MYELOMA_LB_UP

FLNB SCUBE1 P2RX5

2.95e-0447723M14744
CoexpressionDAUER_STAT3_TARGETS_UP

FLNB THBS1 LDLR

3.15e-0448723M12391
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

MFGE8 FBN1 PDE8B ADAM9 LRP1 LAMA2 ITGA4 NOTCH2 TFPI

3.20e-04795729M39050
CoexpressionZHANG_UTERUS_C0_SECRETORY_STROMAL3_NPPC_HIGH_CELL

MFGE8 THBS1 SCUBE1 FBN1 LRP1 COL1A1

3.31e-04337726MM16606
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FBLN7 FLNC THBS1 WIF1 LRP1 LAMA3 FAS

3.45e-04479727M2573
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

VLDLR FBN1 COL1A1

3.55e-0450723M1259
CoexpressionLIM_MAMMARY_STEM_CELL_UP

FBLN7 FLNC THBS1 WIF1 LRP1 LAMA3 FAS

3.62e-04483727MM1082
CoexpressionSMID_BREAST_CANCER_NORMAL_LIKE_UP

PCSK5 NPR1 P2RX5 WIF1 LAMA2 ITGA4 TFPI

3.71e-04485727M8513
CoexpressionSASAI_RESISTANCE_TO_NEOPLASTIC_TRANSFROMATION

VLDLR FBN1 COL1A1

3.99e-0452723MM1118
CoexpressionGSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_UP

CRELD1 P2RX5 LAMA3 TG

4.07e-04126724M8791
CoexpressionZHANG_UTERUS_C2_SECRETORY_STROMAL3_RAMP3_HIGH_CELL

MFGE8 SCUBE1 FBN1 LRP1 COL1A1

4.24e-04229725MM16607
CoexpressionHENDRICKS_SMARCA4_TARGETS_UP

FLNB MFGE8 TEC

4.46e-0454723M15057
CoexpressionVERRECCHIA_EARLY_RESPONSE_TO_TGFB1

ADAM9 LRP1 NOTCH2

4.46e-0454723M4737
CoexpressionGUTIERREZ_CHRONIC_LYMPHOCYTIC_LEUKEMIA_UP

P2RX5 ITGA4

4.82e-0412722M885
CoexpressionGSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP

FLNB TRIM40 FAS SORL1

5.13e-04134724M430
CoexpressionGARCIA_PINERES_PBMC_HPV_16_L1_VLP_AGE_18_25YO_STIMULATED_VS_UNSTIMULATED_0DY_VACCINATION_INDEPENDENT_DN

CASP8AP2 INSR SORL1 TG

5.43e-04136724M41157
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

PAPPA2 PCSK5 FLNC MFGE8 FBN1 FBN2 LRP1 LAMA2 ITGA4 ITGB8 COL1A1

8.56e-093107311gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

PAPPA2 FLNC SCUBE1 FBN1 FBN2 LRP1 ITGB8

2.07e-07122737gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

PAPPA2 PCSK5 FLNC MFGE8 SCUBE1 FBN1 FBN2 AFF3 LRP1 LAMA2 ITGA4 ITGB8 NOTCH2 COL1A1

2.98e-077687314gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

PCSK5 FLNC THBS1 SCUBE1 FBN1 FBN2 AFF3 TAFA1 LRP1 LAMA2 ITGA4 ITGB8 NOTCH2 COL1A1

3.42e-077777314gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

FLNC SCUBE1 FBN1 FBN2 AFF3 LRP1 LAMA2 ITGA4 ITGB8 NOTCH2

3.76e-073567310gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

PAPPA2 FLNC MFGE8 SCUBE1 FBN1 FBN2 LRP1 LARGE1

5.56e-07207738gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

PAPPA2 FLNC SCUBE1 FBN1 FBN2 LRP1 ITGB8 COL1A1

3.53e-06265738gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

PAPPA2 FLNC SCUBE1 FBN1 AFF3 LRP1 ITGA4 ITGB8 NOTCH2

4.28e-06364739gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

FBN1 LRP1 LAMA2 ITGA4 ITGB8

9.28e-0682735gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

SCUBE1 FBN1 LRP1 LAMA2 ITGA4 ITGB8

1.11e-05146736gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500

PAPPA2 FLNC SCUBE1 FBN1 FBN2 LRP1

1.11e-05146736gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

FLNC SCUBE1 FBN1 LRP1 ITGA4 ITGB8

1.15e-05147736gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

PAPPA2 FLNC SCUBE1 FBN1 FBN2 AFF3 LRP1 LAMA2 ITGA4 ITGB8 NOTCH2 COL1A1

1.19e-057737312gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

MFGE8 THBS1 FBN1 LRP1 COL1A1

1.24e-0587735GSM777050_100
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

PAPPA2 FLNC MFGE8 SCUBE1 FBN1 FBN2 AFF3 LRP1 LARGE1

1.30e-05418739gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

FLNC SCUBE1 FBN1 LRP1 ITGA4 ITGB8

1.45e-05153736gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

PAPPA2 FLNC FBN1 LRP1 LAMA2 ITGA4 ITGB8 COL1A1

1.99e-05336738gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

PAPPA2 FLNC MFGE8 SCUBE1 FBN1 FBN2 LRP1 LARGE1

2.03e-05337738gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

FLNC SCUBE1 FBN1 AFF3 LRP1 LAMA2 ITGA4 ITGB8

3.32e-05361738gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_500

FLNC FBN1 LRP1 LAMA2 ITGA4 ITGB8

3.86e-05182736gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

FLNC THBS1 SCUBE1 FBN1 AFF3 LRP1 ITGA4 ITGB8

4.18e-05373738gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500

FLNC THBS1 SCUBE1 FBN1 FBN2 AFF3 LRP1 ITGB8

5.22e-05385738gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlasMESO-30 blastocyst_vs_MESO-30 amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05

PCSK5 FLNB MFGE8 THBS1 ADAM9 TMPRSS6 LAMA3 ITGA4 APOH LDLR COL1A1

5.47e-057617311PCBC_ratio_MESO-30 blastocyst_vs_MESO-30 amniotic fluid MSC_cfr-2X-p05
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_k-means-cluster#5_top-relative-expression-ranked_1000

PCSK5 VLDLR AFF3 LRP1 TFPI COL1A1

6.00e-05197736gudmap_developingGonad_e16.5_epididymis_1000_k5
CoexpressionAtlasDevelopingGonad_e16.5_epididymis_emap-29702_top-relative-expression-ranked_1000

PCSK5 VLDLR RIF1 FBN2 AFF3 WIF1 LRP1 ITGA4 ITGB8 TFPI COL1A1

7.65e-057907311gudmap_developingGonad_e16.5_epididymis_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

PCSK5 FLNC THBS1 SCUBE1 FBN1 AFF3 LRP1 LAMA2 ITGA4 ITGB8 NOTCH2

7.91e-057937311gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

PAPPA2 FLNC MFGE8 THBS1 SCUBE1 FBN1 FBN2 PDE8B AFF3 LRP1 ITGB8

8.27e-057977311gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_top-relative-expression-ranked_1000

PAPPA2 PCSK5 VLDLR RIF1 AFF3 LRP1 LAMA2 ITGA4 ITGB8 TFPI COL1A1

8.46e-057997311gudmap_developingGonad_e18.5_epididymis_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

PAPPA2 CASP8AP2 FLNC MFGE8 SCUBE1 FBN1 FBN2 AFF3 LRP1 NOTCH2 LARGE1

1.15e-048277311gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

PCSK5 FLNC THBS1 FBN1 SCCPDH FBN2 AFF3 TAFA1 LAMA2 TRIM40 P3H4 TFPI SORL1

1.31e-0411487313facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_1000

SCUBE1 ITGA4 ITGB8 NOTCH2

1.59e-0479734gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

FBN1 LRP1 LAMA2 ITGA4 ITGB8

2.02e-04156735gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

PAPPA2 FLNC SCUBE1 FBN1 FBN2 PDE8B AFF3 LRP1 ITGB8 COL1A1

2.13e-047407310gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

PAPPA2 VLDLR FLNC FBN1 FBN2 LRP1 LARGE1

2.14e-04354737gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_200

RIF1 MOV10L1 ITGA4 RNF17 COL1A1

2.20e-04159735gudmap_developingGonad_e14.5_ testes_200
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500

PAPPA2 FLNC SCUBE1 FBN1 FBN2 LRP1 ITGB8

2.25e-04357737gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#4_top-relative-expression-ranked_1000

PCSK5 VLDLR AFF3 WIF1 LRP1 TFPI

2.51e-04256736gudmap_developingGonad_e14.5_ epididymis_1000_k4
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

FLNC FBN1 LRP1 ITGA4 ITGB8

2.61e-04165735gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100

FBN1 ITGA4 ITGB8

2.78e-0437733gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500

FLNC THBS1 FBN1 FBN2 PDE8B LRP1 ITGB8

2.89e-04372737gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#5_top-relative-expression-ranked_100

ITGA4 COL1A1

3.22e-048732gudmap_developingGonad_P2_epididymis_100_k5
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3

PAPPA2 FBLN7 SCUBE1 FBN1 FBN2 AZIN2 TMPRSS6 AFF3 APOH CRB1 COL1A1 TG

3.29e-0410947312ratio_EB_vs_SC_2500_K3
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

PAPPA2 FLNC MFGE8 SCUBE1 FBN1 FBN2 AFF3 LRP1 ITGB8 NOTCH2

3.34e-047837310gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

THBS1 FBN1 LAMA2 COL1A1

3.50e-0497734GSM777043_100
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

FBN1 LRP1 LAMA2 COL1A1

3.50e-0497734GSM777046_100
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#5_top-relative-expression-ranked_500

FBN1 ITGA4 ITGB8 COL1A1

3.64e-0498734gudmap_developingGonad_e14.5_ testes_500_k5
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

PAPPA2 FLNC SCUBE1 FBN1 FBN2 AFF3 LRP1

3.72e-04388737gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

PAPPA2 PCSK5 VLDLR RIF1 AFF3 LRP1 LAMA2 ITGA4 ITGB8 COL1A1

3.84e-047977310gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

PAPPA2 FLNC THBS1 SCUBE1 FBN1 FBN2 PDE8B AFF3 LRP1 ITGB8

3.84e-047977310gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_top-relative-expression-ranked_1000

PCSK5 VLDLR RIF1 AFF3 WIF1 LRP1 ITGA4 ITGB8 TFPI COL1A1

3.99e-048017310gudmap_developingGonad_e14.5_ epididymis_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200

FBN1 LRP1 ITGB8

4.06e-0442733gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#2_top-relative-expression-ranked_1000

RIF1 LRP1 ITGA4 ITGB8 COL1A1

4.31e-04184735gudmap_developingGonad_e14.5_ epididymis_1000_k2
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

PCSK5 FBN1 FBN2 AFF3 TAFA1 TFPI

4.70e-04288736gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

VLDLR THBS1 FBN1 LRP1 LAMA2 FAS COL1A1

5.03e-04408737gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_500

RIF1 FBN1 MOV10L1 ITGA4 RNF17 ITGB8 COL1A1

5.10e-04409737gudmap_developingGonad_e16.5_testes_500
CoexpressionAtlasDevelopingGonad_e14.5_ testes_emap-6710_top-relative-expression-ranked_500

RIF1 FBN1 MOV10L1 ITGA4 RNF17 ITGB8 COL1A1

5.25e-04411737gudmap_developingGonad_e14.5_ testes_500
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#4_top-relative-expression-ranked_1000

CASP8AP2 FBN2 LAMA2 ITGA4 COL1A1

5.62e-04195735gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k4
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

FLNC THBS1 SCUBE1 FBN2 AFF3

6.16e-04199735gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_500

PAPPA2 FLNC SCUBE1 FBN1 FBN2 AFF3 LRP1

6.23e-04423737gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

FLNC THBS1 SCUBE1 FBN1 LRP1 ITGB8

7.03e-04311736gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500

SCUBE1 FBN2 AFF3

7.63e-0452733gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k2_500
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_500

ITGA4 ITGB8 COL1A1

8.07e-0453733gudmap_developingGonad_P2_epididymis_500_k4
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

MFGE8 THBS1 FBN1 ADAM9 LRP1 LAMA2 COL1A1

8.39e-04445737GSM777043_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500

FBN1 LRP1 ITGB8

8.53e-0454733gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_500

FLNC THBS1 SCUBE1 ITGB8

9.10e-04125734gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_500
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#5_top-relative-expression-ranked_500

FBN1 ITGA4 ITGB8 COL1A1

9.94e-04128734gudmap_developingGonad_e18.5_testes_500_k5
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#2_top-relative-expression-ranked_500

FBN1 ITGA4 ITGB8 COL1A1

1.02e-03129734gudmap_developingGonad_e16.5_testes_500_k2
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

PAPPA2 VLDLR MFGE8 THBS1 FBN1 ADAM9 INSR ITGA4 NOTCH2 SORL1

1.02e-039057310gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#2_top-relative-expression-ranked_200

ITGA4 COL1A1

1.03e-0314732gudmap_developingGonad_P2_epididymis_200_k2
CoexpressionAtlasratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1

PAPPA2 FBLN7 FBN1 AZIN2 AFF3 COL1A1

1.05e-03336736ratio_EB_vs_SC_1000_K1
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

FBN1 LRP1 ITGA4 ITGB8

1.05e-03130734gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_200

FBN1 ITGA4 ITGB8

1.10e-0359733gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_200
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#1_top-relative-expression-ranked_1000

RIF1 ITGA4 ITGB8 COL1A1

1.24e-03136734gudmap_developingGonad_P2_epididymis_1000_k1
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#5_top-relative-expression-ranked_1000

PAPPA2 PCSK5 VLDLR TFPI COL1A1

1.27e-03234735gudmap_developingGonad_e18.5_epididymis_1000_k5
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_200

SCUBE1 FBN1 ITGA4 ITGB8

1.31e-03138734gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_200
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#2_top-relative-expression-ranked_1000

LAMA2 ITGA4 ITGB8 COL1A1

1.35e-03139734gudmap_developingGonad_e18.5_epididymis_1000_k2
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_1000

PAPPA2 FLNC MFGE8 THBS1 FBN2

1.42e-03240735gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_1000
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_1000

EPHB6 PCSK5 FBN1 FBN2 AFF3 TAFA1 ITGA4 TEC TFPI

1.52e-03791739gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_500

PAPPA2 THBS1 FBN1 PDE8B MOV10L1 AFF3 COL1A1

1.53e-03494737JC_fibro_500
CoexpressionAtlaskidney_adult_RenCorpuscGlomer_k-means-cluster#4_top-relative-expression-ranked_1000

MFGE8 PDE8B ADAM9 ITGA4

1.70e-03148734gudmap_kidney_adult_RenCorpuscGlomer_k4_1000
CoexpressionAtlasdev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_100

MOV10L1 RNF17

1.72e-0318732gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k2_100
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

THBS1 FBN1 HMCN2 AZIN2 LRP1 LAMA2 NOTCH2 TFPI COL1A1

4.75e-11194769d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell(2)_Fibroblasts-(20)_Fibro-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

FBLN7 FLNC FBN1 HMCN2 TMPRSS6 LRP1 LAMA2 COL1A1

1.18e-09188768409a7b69d02e87084ca955e3fe6c77230dee8861
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 FBLN7 THBS1 TMPRSS6 WIF1 LRP1 P3H4 COL1A1

1.85e-09199768edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 MFGE8 NPR1 FBN1 LRP1 LAMA2 TFPI COL1A1

1.93e-0920076874ad0ae592252060ee294d7483327d765a6ba1dd
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 FLNB FBN1 ADAM9 WIF1 COL1A1 LARGE1

2.43e-08179767ce3ca7f3a5864e62307aa744a3173f350a90df28
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

PCSK5 FBN1 HMCN2 LRP1 LAMA2 TFPI COL1A1

3.29e-081877674ea486991f66c29728d127171a07b81404ec0b78
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 THBS1 TMPRSS6 AFF3 WIF1 LRP1 COL1A1

3.94e-08192767b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 THBS1 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

4.08e-0819376749600db68ed65cafc67bd45a285b364e4f5f88af
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 THBS1 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

4.08e-0819376745b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCelldroplet-Heart-nan-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBLN7 TMPRSS6 AFF3 LRP1 LAMA2 COL1A1

4.23e-0819476720a0439fa02c5f8107612e34c7ab54120b9b8573
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 THBS1 TMPRSS6 AFF3 WIF1 LRP1 COL1A1

4.38e-08195767d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB6 PAPPA2 PCSK5 FLNC THBS1 WIF1 COL1A1

4.38e-08195767d32716a12014522492becbde1088dc1106308490
ToppCell(3)_Chondrocytes-(30)_Chondro|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

PAPPA2 AFF3 WIF1 LAMA2 TFPI SORL1 COL1A1

4.38e-08195767f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCelldroplet-Lung-nan-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB6 PAPPA2 PCSK5 FLNC THBS1 WIF1 COL1A1

4.38e-08195767b913d5df50c88a3a255f516a1aa42419c6701e1e
ToppCellfacs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 FLNC FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

4.53e-0819676765f2f51e17f1869f3468813127b96d3048d8ad41
ToppCellfacs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 FLNC FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

4.53e-08196767e4ed897900a6472738bc6be2fb4817192727225d
ToppCellfacs-SCAT-Fat-18m-Mesenchymal|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 FLNC FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

4.53e-081967672cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 PDE8B AFF3 LRP1 LAMA2 COL1A1

4.53e-08196767ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 PDE8B AFF3 LRP1 LAMA2 COL1A1

4.53e-0819676730ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MFGE8 THBS1 FBN1 LRP1 LAMA2 TFPI COL1A1

4.70e-08197767ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 FBN1 WIF1 LRP1 LAMA2 P3H4 COL1A1

4.86e-081987671b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MFGE8 NPR1 FBN1 LRP1 LAMA2 TFPI COL1A1

5.21e-08200767cfea2f9d85646c9b722150551ff2e8fc4f6cc98a
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

THBS1 FBN1 WIF1 LRP1 LAMA2 TFPI COL1A1

5.21e-08200767f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PAPPA2 MFGE8 PDE8B WIF1 LRP1 LAMA2 COL1A1

5.21e-08200767251fd2923f108cd2086961d897244b392c32ad54
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MFGE8 NPR1 FBN1 LRP1 LAMA2 TFPI COL1A1

5.21e-08200767f6cf98aad53aa8b3fa02cf874d6f7cd75530a213
ToppCellTracheal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 MFGE8 FBN1 LRP1 LAMA2 TFPI COL1A1

5.21e-082007677ba292c30d915e66ebc8026fa76492cedf64700e
ToppCellTracheal-10x5prime-Stromal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 MFGE8 FBN1 LRP1 LAMA2 TFPI COL1A1

5.21e-08200767920e6036c0a9c0089d0d898673daf9dd9d7279fc
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

MFGE8 FBN2 PDE8B LRP1 LAMA2 NOTCH2 TFPI

5.21e-08200767bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)-|Striatum / BrainAtlas - Mouse McCarroll V32

PAPPA2 FLNC THBS1 FBN1 TEC COL1A1

1.15e-07134766a3547a68012d879d4dfe80394eace70808722e43
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Col3a1_(Mural.Rgs5Acta2.Col3a1)|Striatum / BrainAtlas - Mouse McCarroll V32

PAPPA2 FLNC THBS1 FBN1 TEC COL1A1

1.15e-071347669458e2d0dbc18d9025b66b59f3ecc2fbc5384940
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TMPRSS6 WIF1 LAMA2 VSIG8 RNF17

6.12e-071787666d9ecfaeb50d562899380de379ebf7b99fd8adc9
ToppCellfacs-Marrow-Granulocytes-3m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TMPRSS6 WIF1 LAMA2 VSIG8 RNF17

6.12e-07178766d3f518cd75b02e85d45cbb9b2eff30f0272512a8
ToppCellSomatosensory_Cortex_(S1)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHB6 FBLN7 MFGE8 NOTCH2NLA LAMA3 ITGA4

6.33e-0717976682348bf56a4525b2f485696cab5b2ea6e96c2f91
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN7 FBN1 HMCN2 LRP1 LAMA2 COL1A1

6.54e-071807669adebde5f4ca6dcb90e9113622862e14298465ac
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

6.97e-07182766f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellnormal_Lung-Fibroblasts-Myofibroblasts|normal_Lung / Location, Cell class and cell subclass

FLNC FBN1 HMCN2 MOV10L1 P3H4 COL1A1

7.43e-071847660b336489c10e8c3c957795dd845454f03404382b
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

7.92e-0718676635c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

7.92e-07186766d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ADAM9 AFF3 LAMA2 LDLR TFPI COL1A1

8.17e-07187766a9316e2818217ec5feae9cf8816f7249803caee6
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

8.43e-071887667191087d8754f5e8700e3d744cd920ee26db1e57
ToppCelldroplet-Limb_Muscle-nan-21m-Mesenchymal-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC FBN1 TMPRSS6 LRP1 LAMA2 LDLR

8.69e-071897660a8b827bba1efd885ad6c06929251c741dc3a541
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

THBS1 FBN1 LRP1 LAMA2 NOTCH2 COL1A1

8.69e-071897660c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 LAMA2 NOTCH2 TFPI LARGE1

8.96e-071907661121eb607a984c59fbffe7220837fc178745aa55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 LAMA2 NOTCH2 TFPI LARGE1

8.96e-07190766048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellfacs-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PAPPA2 PCSK5 THBS1 TAFA1 WIF1 COL1A1

9.24e-07191766fd8331c7abdd999f55ba43d307945c6abfccbf84
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MFGE8 THBS1 FBN1 LRP1 LAMA2 TFPI

9.24e-071917664e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 FBN1 TMPRSS6 AFF3 LRP1 COL1A1

9.24e-071917661b26056df078674f37a6c06f6256b30cfcec21a7
ToppCellfacs-Aorta-Heart-18m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 LRP1 LAMA2 P3H4 NOTCH2 COL1A1

9.53e-071927666d4fe7ea278efa4b9d43f8a3c282bc0e0e9abaea
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

9.53e-071927665105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

9.53e-07192766d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 THBS1 TMPRSS6 LRP1 LAMA2 COL1A1

9.53e-0719276611088878043a6ff95ba1970361256a82e434b80a
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 LRP1 LAMA2 P3H4 NOTCH2 COL1A1

9.53e-071927662c6406bc97c3224099b94a43f2890f057b528fa6
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THBS1 FBN1 LRP1 ITGB8 TFPI COL1A1

9.53e-07192766df1545670370fb1010c567cd059c2783eab315f7
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

PCSK5 FBN1 LRP1 LAMA2 TFPI COL1A1

9.53e-0719276660b1312e84f6d6448365a952469c506c00b5fe93
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 LRP1 LAMA2 P3H4 NOTCH2 COL1A1

9.53e-0719276647aed7c8e6f5ce1084821212a04f568319e65fd6
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 VLDLR FBN1 LRP1 LAMA2 COL1A1

9.82e-07193766ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 VLDLR FBN1 LRP1 LAMA2 COL1A1

9.82e-0719376622c58032e58730715224d7934968ce92d150b0e8
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBLN7 FBN1 TMPRSS6 LAMA2 COL1A1

9.82e-07193766316ebdf15f75d88c348f909b643fcd315364ca84
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

9.82e-07193766f1199518c3626fd29bfce65070dd21a660671213
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 HMCN2 LRP1 LAMA2 COL1A1

9.82e-07193766dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCelldroplet-Fat-Scat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBLN7 FBN1 TMPRSS6 LAMA2 COL1A1

9.82e-071937661afdd3f7d703f4204a2cbfe40e135ac7b09213f7
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

9.82e-07193766f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCellLA|World / Chamber and Cluster_Paper

PCSK5 FBN1 HMCN2 PDE8B AFF3 LRP1

9.82e-07193766d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

9.82e-0719376685faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCelldroplet-Fat-Scat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR FBLN7 FBN1 TMPRSS6 LAMA2 COL1A1

9.82e-071937668dc6db335678f3a5cfd36026ad811fed8d9cb4bc
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 VLDLR FBN1 LRP1 LAMA2 COL1A1

9.82e-07193766573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 HMCN2 LRP1 LAMA2 COL1A1

9.82e-07193766e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellfacs-MAT-Fat-3m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 FBN1 TMPRSS6 LRP1 LAMA2 COL1A1

9.82e-07193766110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNB FLNC NPR1 FBN1 LRP1 LAMA2

1.01e-061947667b6ec45adb7ece3c8a7b78c5782413b5825effe2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.01e-06194766240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.01e-06194766ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.01e-06194766e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.04e-06195766d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.04e-0619576649c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK5 MFGE8 FBN1 LRP1 LAMA2 COL1A1

1.04e-06195766f54bc4454270ff06e85596f98199372b50d0179f
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 TMPRSS6 AFF3 LRP1 LAMA2 COL1A1

1.04e-06195766613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

PCSK5 FBN1 HMCN2 LRP1 LAMA2 TFPI

1.04e-06195766a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 TMPRSS6 AFF3 LRP1 LAMA2 COL1A1

1.04e-061957669ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.04e-06195766dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.04e-06195766edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.04e-061957663c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MFGE8 THBS1 FBN1 LRP1 LAMA2 TFPI

1.04e-06195766fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.04e-0619576644d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FBN1 PDE8B LAMA2 ITGA4 TFPI COL1A1

1.07e-06196766cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 WIF1 LRP1 LAMA2 P3H4 COL1A1

1.07e-0619676659b5b5a0c123d0423abd19c312514849004b903b
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FLNC MFGE8 HMCN2 AFF3 LAMA2 COL1A1

1.07e-0619676624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellMesenchymal_cells-Fibro/Chondro_p.|World / Lineage and Cell class

FBLN7 MFGE8 SCUBE1 WIF1 P3H4 COL1A1

1.07e-06196766ddc168849e0e97005a111be004463bb72d433853
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.07e-06196766fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCelldroplet-Heart-HEART-1m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 WIF1 LRP1 LAMA2 P3H4 COL1A1

1.07e-061967661eb14182ef26e6141f510d397b00bf8a12efda3e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.07e-06196766802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TMPRSS6 LRP1 LAMA2 NOTCH2 COL1A1

1.07e-06196766ad1838dabd043cb140260843e3527d8c7d58850e
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FBLN7 SCUBE1 FBN1 HMCN2 MOV10L1 COL1A1

1.07e-06196766614a07334707eafe238d5cb7b080a3ca796a1920
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FBN1 PDE8B LAMA2 ITGA4 TFPI COL1A1

1.07e-0619676644e2df1b61e3819eae7e482bef0a733afe852d67
ToppCellfacs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 TMPRSS6 LRP1 LAMA2 NOTCH2 COL1A1

1.07e-06196766cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCelldroplet-Heart-HEART-1m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 WIF1 LRP1 LAMA2 P3H4 COL1A1

1.11e-06197766b16add329bb35a558287ede51353010dde5bc029
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK5 FBN1 MOV10L1 LRP1 LAMA2 RHO

1.11e-061977660dd71e399f253787fa546a7e90c5373180b89ffd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.11e-06197766ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MFGE8 FBN1 AFF3 LRP1 LAMA2 COL1A1

1.11e-0619776637f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NPR1 FBN2 P2RX5 AFF3 WIF1 COL1A1

1.11e-061977663fe665c0277d091290b63f0dd24c0c6536a45309
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN7 THBS1 TMPRSS6 WIF1 LRP1 COL1A1

1.11e-06197766cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ComputationalMetal / Ca ion binding.

FBN1 FBN2 DSG3 ADAM9 LRP1 PPA1 LTF LDLR CRB1

1.21e-08133529MODULE_324
ComputationalAdhesion molecules.

MFGE8 FBN1 FBN2 DSG3 LAMA2 LAMA3 COL1A1

4.70e-06141527MODULE_122
ComputationalGenes in the cancer module 236.

VLDLR LDLR SORL1

8.28e-0518523MODULE_236
DrugLMWH

EPHB6 PAPPA2 THBS1 DSG3 ADAM9 LRP1 LAMA2 LAMA3 LTF ITGA4 APOH LDLR TFPI COL1A1

1.73e-086637214CID000000772
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

THBS1 INSR LAMA3 FAS LDLR NOTCH2 TFPI SORL1

3.18e-081557286817_DN
Drugepicholesterol

VLDLR FLNB MFGE8 LRP1 LTF APOH FAS LDLR MVK RHO TFPI SORL1 COL1A1

8.72e-086367213CID000000304
Drugiodide

EPHB6 PCSK5 VLDLR FLNB MFGE8 NPR1 INSR LRP1 LTF LDLR BRAP TG

1.05e-075347212CID000024841
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT_HG-U133A

ADAM9 INSR ITGA4 LDLR NOTCH1 NOTCH2 SORL1

7.45e-071607276133_DN
DrugRgd Peptide

MFGE8 THBS1 FBN1 FBN2 LAMA3 ITGA4 ITGAD COL1A1

8.80e-07239728CID000104802
Drug4-oxoretinoic acid

THBS1 LAMA2 LAMA3 ITGA4 FAS COL1A1

1.73e-06115726ctd:C002202
Drug2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide

THBS1 FBN1 ITGA4 COL1A1

2.71e-0631724ctd:C577942
DrugDydrogesterone [152-62-5]; Down 200; 12.8uM; HL60; HT_HG-U133A

JAG2 EPHB6 TEC LDLR NOTCH2 MVK COL1A1

2.79e-061957272156_DN
DrugLactobionic acid [96-82-2]; Down 200; 11.2uM; PC3; HT_HG-U133A

THBS1 PDE8B INSR FAS NOTCH1 TFPI LARGE1

2.89e-061967276605_DN
DrugRibavirin [36791-04-5]; Down 200; 16.4uM; HL60; HT_HG-U133A

FLNB NR2F6 UBR4 NOTCH1 BRAP TFPI COL1A1

3.09e-061987273142_DN
Drugisocycloheximide

THBS1 AZIN2 INSR LRP1 LAMA2 LAMA3 LTF APOH FAS LDLR SORL1 COL1A1 TG

4.58e-069057213CID000002900
Drugalitretinoin

THBS1 INSR LAMA2 LAMA3 ITGA4 FAS RHO COL1A1

4.89e-06301728ctd:C103303
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

THBS1 FBN1 LAMA2 LAMA3 COL1A1

6.58e-0683725CID011968896
Drug(2s,5s)-5-Carboxymethylproline

THBS1 FBN1 ITGA4 APOH ITGAD FAS COL1A1 TG

6.66e-06314728CID000447989
Drugpyrachlostrobin

FLNB FLNC THBS1 SCUBE1 FBN1 ADAM9 FAS NOTCH1 NOTCH2 MVK SORL1 COL1A1

8.29e-068117212ctd:C513428
DrugAlpha-D-Mannose

LTF APOH LDLR RHO

8.52e-0641724DB02944
Drugmonacolin X

EPHB6 LDLR

9.86e-062722CID000125978
DrugAC1O5L03

EPHB6 RHO

9.86e-062722CID006436054
Drugnifurzide

EPHB6 RHO

9.86e-062722CID009571044
Drug25-hydroxycholesterol

INSR LRP1 LDLR NOTCH2 MVK SORL1

1.17e-05160726CID000065094
Druglanthanum fluoride

AFF3 ITGA4 TEC

1.34e-0515723CID000083675
Drugpuerarin

FBN1 FBN2 DSG3 INSR LDLR

1.48e-0598725ctd:C033607
Drughyaluronan

FBN1 FBN2 DSG3 LAMA3 ITGA4 BRAP COL1A1

1.97e-05263727CID000024759
DrugGSK1210151A

THBS1 FBN1 ITGA4 COL1A1

2.22e-0552724ctd:C568713
Druglosartan

THBS1 NPR1 FBN1 FBN2 MOV10L1 ITGA4 ITGAD COL1A1

2.54e-05378728CID000003961
DrugSR121463

LTF RHO BRAP

2.83e-0519723CID000158348
Drugpitavastatin

LRP1 LDLR TFPI SORL1 COL1A1

3.09e-05114725CID005282451
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

VLDLR FLNB UBR4 FAS NOTCH2 SORL1

3.18e-051917264168_DN
DrugEpiandrosterone [481-29-8]; Up 200; 13.8uM; PC3; HT_HG-U133A

RIF1 NR2F6 APOH LDLR MVK COL1A1

3.47e-051947264626_UP
DrugFlurandrenolide [1524-88-5]; Up 200; 9.2uM; PC3; HT_HG-U133A

PAPPA2 RIF1 TMPRSS6 INSR MTMR3 COL1A1

3.47e-051947263679_UP
Drugchloroquine

EPHB6 NPR1 INSR LRP1 FAS LDLR COL1A1

3.52e-05288727CID000002719
DrugCimetidine [51481-61-9]; Up 200; 15.8uM; PC3; HT_HG-U133A

PAPPA2 RIF1 INSR LAMA2 ITGB8 COL1A1

3.57e-051957264063_UP
DrugAC1L35RZ

LTF LDLR RHO TG

3.67e-0559724CID000135074
DrugParbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A

PCSK5 TMPRSS6 UBR4 INSR AFF3 RHO

3.67e-051967264357_UP
DrugClidinium bromide [3485-62-9]; Up 200; 9.2uM; HL60; HT_HG-U133A

PCSK5 KMT2D INSR RHO COL1A1 LARGE1

3.67e-051967262734_UP
DrugXylazine [7361-61-7]; Up 200; 18.2uM; PC3; HT_HG-U133A

PAPPA2 DSG3 AFF3 RRP8 ITGB8 NOTCH2

3.67e-051967264066_UP
DrugSulfamethazine sodium salt [1981-58-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

NPR1 FBN1 TMPRSS6 INSR MTMR3 COL1A1

3.67e-051967263847_UP
DrugDA-8159

LTF APOH BRAP

3.87e-0521723CID006918523
DrugALT-711

LAMA3 LTF COL1A1

3.87e-0521723CID000216304
DrugNifuroxazide [965-52-6]; Up 200; 14.6uM; PC3; HT_HG-U133A

NPR1 APOH FAS RNF17 ITGB8 TFPI

3.89e-051987264253_UP
DrugQuinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A

VLDLR RIF1 NR2F6 AFF3 LRP1 COL1A1

3.89e-051987264529_UP
DrugCorticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A

FBN1 TMPRSS6 MTMR3 LAMA2 RRP8 TEC

3.89e-051987264145_UP
DrugDO 897/99; Down 200; 8.2uM; MCF7; HT_HG-U133A

PAPPA2 CRELD1 NR2F6 THBS1 FAS SORL1

3.89e-051987262877_DN
DrugCorticosterone [50-22-6]; Up 200; 11.6uM; PC3; HT_HG-U133A

PAPPA2 RIF1 AFF3 LAMA2 TEC ITGB8

3.89e-051987264064_UP
Drugcilostamide

NPR1 FBN2 PDE8B LDLR COL1A1

3.95e-05120725CID000002753
DrugTocainide hydrochloride; Up 200; 17.4uM; PC3; HT_HG-U133A

PAPPA2 DSG3 TMPRSS6 MTMR3 FAS CRB1

4.00e-051997264256_UP
Drugolanzapine

VLDLR PDE8B APOH LDLR COL1A1

4.11e-05121725ctd:C076029
Drug4-APP

LDLR MVK BRAP TFPI

4.19e-0561724CID000075420
DrugPVLA

ITGA4 FAS COL1A1

4.47e-0522723CID000126094
Drugchondroitin sulfate

EPHB6 PAPPA2 THBS1 LAMA3 LTF ITGA4 TFPI COL1A1

4.76e-05413728CID000024766
DrugChr 5

VLDLR THBS1 LDLR MVK TG

4.80e-05125725CID006448119
DrugDiethylstilbestrol

VLDLR NR2F6 MFGE8 THBS1 KMT2D FBN2 CGRRF1 TMPRSS6 AFF3 LTF FAS NOTCH1 TFPI COL1A1

5.03e-0513057214ctd:D004054
DrugSalmfamide 1

FBN2 TG

5.89e-054722CID005487416
Drugdimethylaminopropylamine

LDLR TG

5.89e-054722CID000007993
DrugAR 12456

EPHB6 LDLR

5.89e-054722CID000127644
DrugAR 12465

EPHB6 LDLR

5.89e-054722CID000127645
DrugCBQCA

EPHB6 LTF

5.89e-054722CID000125448
DrugAC1O3R10

FLNB LDLR

5.89e-054722CID006335025
Drugepichlorohydrin triethanolamine

RHO TG

5.89e-054722CID000163191
Drugconivaptan

LTF RHO BRAP

6.63e-0525723CID000151171
Drugmethyl aminolevulinate

APOH LDLR BRAP

7.48e-0526723CID000157921
DrugAC1MS9WM

EPHB6 MFGE8 INSR

8.40e-0527723CID003530978
Drugo,p'-DDT

CASP8AP2 MFGE8 THBS1 FBN2 LTF FAS LDLR NOTCH1

8.79e-05451728ctd:C016340
Drug1-aminoindan

DSG3 WIF1 ITGA4 TG

8.95e-0574724CID000123445
Drugphenoxodiol

LTF APOH FAS

9.39e-0528723CID000219100
Drugdimyristoylphosphatidylglycerol

LTF APOH LDLR

9.39e-0528723CID000107767
DrugFr 6

INSR TG

9.80e-055722CID000449013
Drugronipamil

EPHB6 LDLR

9.80e-055722CID000065638
Drugdimethylmethylene

LTF MVK

9.80e-055722CID006432418
DrugAR 12463

EPHB6 LDLR

9.80e-055722CID000119335
DrugEpi Lovastatin

VLDLR THBS1 LRP1 LDLR MVK TFPI SORL1

1.02e-04341727CID000003962
Drugezetimibe

LRP1 LTF LDLR BRAP SORL1

1.04e-04147725CID000150311
Drugmonatepil

LRP1 LDLR SORL1

1.04e-0429723CID000060810
DrugSNAC

EPHB6 NPR1 TFPI

1.04e-0429723CID000158789
DrugYIGSR

LAMA2 LAMA3 ITGA4 COL1A1

1.15e-0479724CID000123977
DrugDB00520

LTF APOH BRAP

1.16e-0430723CID000123623
Drugvernakalant

LTF APOH BRAP

1.16e-0430723CID009930048
DrugN-acetylhexosamine

MFGE8 INSR LTF ITGA4 APOH ITGAD LDLR RHO

1.20e-04472728CID000000899
Drugrhamnose

MFGE8 THBS1 INSR LTF NOTCH2 COL1A1 TG

1.33e-04356727CID000000840
DrugGrgds

THBS1 LAMA3 ITGA4 COL1A1

1.40e-0483724CID000123811
Drugrosavin

FBN1 FBN2 DSG3

1.41e-0432723ctd:C529148
DrugWHI-P258

INSR TEC

1.47e-046722CID000003798
Drug2-formylquinoline

EPHB6 LTF

1.47e-046722CID000079619
Drug2-GG

LTF TG

1.47e-046722CID016058668
DrugB 104

LDLR RHO

1.47e-046722CID006509829
Drug3-hydroxy-4-pyridone

LTF TG

1.47e-046722CID000105085
DrugC6E3

VLDLR LTF LDLR MVK

1.53e-0485724CID000094362
Drugisodesmosine

FBN1 FBN2 COL1A1

1.55e-0433723CID000013811
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

THBS1 ADAM9 FAS NOTCH2 SORL1

1.59e-041617253556_DN
Drugprobucol

VLDLR LRP1 LDLR TFPI SORL1

1.63e-04162725CID000004912
Drugdipyridamole

CASP8AP2 NPR1 PDE8B BRAP COL1A1

1.63e-04162725CID000003108
DrugSmoke

JAG2 FLNC THBS1 DSG3 PDE8B AFF3 LTF NOTCH1 TFPI SORL1 COL1A1

1.64e-049377211ctd:D012906
DrugToxins, Biological

MFGE8 ADAM9 INSR LAMA2 LAMA3 ITGA4 FAS LDLR COL1A1

1.66e-04632729ctd:D014118
DrugAC1O0B8G

JAG2 THBS1 FBN2 LAMA2 LAMA3 LDLR

1.81e-04262726CID000091605
Drugphosphoarginine

EPHB6 BRAP TFPI

1.85e-0435723CID000092150
Drugmanganese

NPR1 INSR LAMA2 LAMA3 PPA1 LTF ITGA4 ITGAD BRAP COL1A1

1.85e-047917210CID000023930
Drugammonium perchlorate

COL1A1 TG

2.05e-047722ctd:C053506
Drug37474A

DSG3 RHO

2.05e-047722CID004330138
Drug5 PV

DSG3 LDLR

2.05e-047722CID000016757
DiseaseMalignant neoplasm of breast

JAG2 FLNB RIF1 NR2F6 MFGE8 THBS1 KMT2D TMPRSS6 UBR4 MTMR3 LAMA2 PPA1 NOTCH1 NOTCH2 SORL1

3.21e-0810747115C0006142
DiseaseBladder Neoplasm

KMT2D LAMA2 CHD6 FAS NOTCH1 NOTCH2

1.14e-06140716C0005695
DiseaseMalignant neoplasm of urinary bladder

KMT2D LAMA2 CHD6 FAS NOTCH1 NOTCH2

1.19e-06141716C0005684
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN1 FBN2 NOTCH1 COL1A1

8.24e-0653714C4707243
DiseaseAlzheimer's disease (is_implicated_in)

VLDLR LRP1 FAS LDLR SORL1

1.71e-05132715DOID:10652 (is_implicated_in)
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNB FLNC

1.71e-053712DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNB FLNC

1.71e-053712DOID:0111190 (implicated_via_orthology)
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN2

1.71e-053712DOID:65 (implicated_via_orthology)
Diseasescoliosis (is_implicated_in)

FBN1 FBN2

3.41e-054712DOID:0060249 (is_implicated_in)
Diseasetyrosine-protein kinase TEC measurement

TEC TEC

3.41e-054712EFO_0020830
Diseaseretinitis pigmentosa (implicated_via_orthology)

EYS CRB1 RHO

3.75e-0527713DOID:10584 (implicated_via_orthology)
Diseaseadult T-cell leukemia/lymphoma (is_implicated_in)

FAS NOTCH1

5.68e-055712DOID:0050523 (is_implicated_in)
Diseaseautosomal recessive limb-girdle muscular dystrophy (is_implicated_in)

JAG2 LAMA2

5.68e-055712DOID:0110274 (is_implicated_in)
Diseasedescending aortic diameter

PAPPA2 FLNB FBN1 LRP1

6.16e-0588714EFO_0021788
Diseasecortical thickness

JAG2 FLNB FBLN7 THBS1 SCUBE1 FBN1 FBN2 MTMR3 LRP1 LAMA2 TG

6.74e-0511137111EFO_0004840
Diseaseretinitis pigmentosa

EYS ITGA4

8.51e-056712MONDO_0019200
Diseasemyocardial infarction (is_implicated_in)

NPR1 LRP1 APOH TFPI

9.75e-0599714DOID:5844 (is_implicated_in)
Diseaseliver disease (biomarker_via_orthology)

DNAJA2 FAS

1.19e-047712DOID:409 (biomarker_via_orthology)
DiseaseAutoimmune Lymphoproliferative Syndrome Type 2B

FAS COL1A1

1.19e-047712C1846545
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2

1.19e-047712DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2

1.19e-047712DOID:3620 (implicated_via_orthology)
DiseaseLymphoma

FAS NOTCH1 NOTCH2

1.24e-0440713C0024299
DiseaseAutoimmune Diseases

FAS COL1A1 TG

1.43e-0442713C0004364
DiseaseGlioblastoma Multiforme

JAG2 EPHB6 NOTCH1 NOTCH2

1.52e-04111714C1621958
Diseasebody surface area

PAPPA2 PCSK5 FBN1 FBN2 INSR MTMR3 ITGB8 MVK

1.55e-04643718EFO_0022196
Diseasesystemic lupus erythematosus (is_marker_for)

FAS LDLR TFPI

2.01e-0447713DOID:9074 (is_marker_for)
DiseaseFibrosis

THBS1 NPR1 COL1A1

2.41e-0450713C0016059
DiseaseCirrhosis

THBS1 NPR1 COL1A1

2.41e-0450713C1623038
Diseaseaortic aneurysm

FBN1 LRP1

2.54e-0410712EFO_0001666
Diseasesystolic blood pressure, alcohol drinking

EYS FBN1 INSR BRAP

2.62e-04128714EFO_0004329, EFO_0006335
DiseaseMammary Carcinoma, Human

JAG2 NR2F6 MFGE8 THBS1 KMT2D NOTCH1 NOTCH2

2.70e-04525717C4704874
DiseaseMammary Neoplasms, Human

JAG2 NR2F6 MFGE8 THBS1 KMT2D NOTCH1 NOTCH2

2.70e-04525717C1257931
DiseaseMammary Neoplasms

JAG2 NR2F6 MFGE8 THBS1 KMT2D NOTCH1 NOTCH2

2.76e-04527717C1458155
DiseaseMicrophthalmos

KMT2D CRB1

3.10e-0411712C0026010
DiseaseBreast Carcinoma

JAG2 NR2F6 MFGE8 THBS1 KMT2D NOTCH1 NOTCH2

3.13e-04538717C0678222
DiseaseDiffuse Large B-Cell Lymphoma

KMT2D FAS NOTCH2

3.20e-0455713C0079744
Diseasegraft-versus-host disease (is_marker_for)

FAS TFPI

3.71e-0412712DOID:0081267 (is_marker_for)
DiseaseCongenital muscular dystrophy

LAMA2 LARGE1

3.71e-0412712cv:C0699743
DiseaseAlzheimer's disease (biomarker_via_orthology)

ADAM9 INSR LRP1

3.75e-0458713DOID:10652 (biomarker_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

NOTCH1 NOTCH2

5.87e-0415712C0496930
DiseaseBenign neoplasm of bladder

NOTCH1 NOTCH2

5.87e-0415712C0154017
DiseaseCarcinoma in situ of bladder

NOTCH1 NOTCH2

5.87e-0415712C0154091
DiseaseGraves' disease (is_marker_for)

FAS TG

5.87e-0415712DOID:12361 (is_marker_for)
Diseaserenal cell carcinoma (is_implicated_in)

WIF1 LTF FAS

6.24e-0469713DOID:4450 (is_implicated_in)
DiseaseEndometrioma

NR2F6 FBN1 LTF ITGB8

6.24e-04161714C0269102
DiseaseEndometriosis

NR2F6 FBN1 LTF ITGB8

6.24e-04161714C0014175
DiseaseNon-alcoholic Fatty Liver Disease

VLDLR FAS LDLR

6.51e-0470713C0400966
DiseaseNonalcoholic Steatohepatitis

VLDLR FAS LDLR

6.51e-0470713C3241937
Diseasediabetic retinopathy (implicated_via_orthology)

INSR ITGA4

6.70e-0416712DOID:8947 (implicated_via_orthology)
DiseaseSjogren's syndrome (implicated_via_orthology)

THBS1 FAS

7.58e-0417712DOID:12894 (implicated_via_orthology)
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

AFF3 TEC TET3 TEC

7.65e-04170714EFO_0000685, EFO_0007791, EFO_0007837
DiseaseRetinitis pigmentosa

EYS CRB1 RHO

7.66e-0474713cv:C0035334
Diseasejuvenile idiopathic arthritis

AFF3 LAMA2 FAS

7.66e-0474713EFO_0002609
Diseasebody weight

PAPPA2 PCSK5 CRELD1 EYS FBN2 INSR MTMR3 FAS CRB1 BRAP

8.45e-0412617110EFO_0004338
DiseaseCarcinoma of bladder

NOTCH1 NOTCH2

8.52e-0418712C0699885
DiseaseDisproportionate short stature

FLNB FBN1 COL1A1

8.60e-0477713C0878659
Diseasereticulocyte count

FLNB TMPRSS6 INSR MTMR3 LAMA3 ITGA4 TRIM40 ITGAD BRAP

8.80e-041045719EFO_0007986
Diseasecentral corneal thickness

FBLN7 FBN1 FBN2 AFF3 COL1A1

9.03e-04309715EFO_0005213
DiseaseGlioblastoma

JAG2 NOTCH1 NOTCH2

9.26e-0479713C0017636
Diseasereticulocyte measurement

FLNB TMPRSS6 INSR AFF3 MTMR3 ITGA4 TRIM40 ITGAD BRAP

9.28e-041053719EFO_0010700
Diseasecystathionine measurement

TEC TEC

9.51e-0419712EFO_0010474
DiseaseGiant Cell Glioblastoma

JAG2 NOTCH1 NOTCH2

1.11e-0384713C0334588
Diseasemacula measurement

FBN1 WIF1 MTMR3 SORL1

1.13e-03189714EFO_0008375
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

APOH LDLR

1.16e-0321712EFO_0022246
DiseaseSchizophrenia

JAG2 VLDLR THBS1 LRP1 LAMA2 APOH FAS BRAP

1.25e-03883718C0036341
Diseasechildhood onset asthma

INSR LRP1 LAMA2 ITGB8 BRAP

1.27e-03334715MONDO_0005405
Diseaseseminoma (is_marker_for)

INSR FAS

1.28e-0322712DOID:4440 (is_marker_for)
DiseaseSplenomegaly

FAS NOTCH1

1.28e-0322712C0038002
Diseaseabdominal fat cell number

FLNC VSIG8 TEC TEC

1.35e-03198714EFO_0021534
Diseasecortical surface area measurement

JAG2 FLNB THBS1 SCUBE1 FBN1 FBN2 LAMA2 ITGB8 TFPI TG

1.37e-0313457110EFO_0010736
DiseaseCarcinoma, Pancreatic Ductal

JAG2 NOTCH1

1.52e-0324712C0887833
Diseasetemperament and character inventory

FBN2 TG

1.52e-0324712EFO_0004825
DiseaseSquamous cell carcinoma of esophagus

KMT2D NOTCH1 NOTCH2

1.58e-0395713C0279626
DiseaseCerebral Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0750935
DiseaseIntracranial Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0750936
DiseaseAstrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0004114
DiseaseGrade I Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0205768
DiseaseMixed oligoastrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0547065
DiseasePilocytic Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0334583
DiseaseJuvenile Pilocytic Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0280783
DiseaseDiffuse Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0280785
DiseaseChildhood Cerebral Astrocytoma

NOTCH1 NOTCH2

1.65e-0325712C0338070
DiseaseDisorder of eye

EYS ADAM9 CRB1 RHO

1.73e-03212714C0015397
Diseasepulse pressure measurement

PAPPA2 FLNB FBN1 FBN2 INSR LRP1 TEC FAS TEC P3H4

1.77e-0313927110EFO_0005763
Diseasesciatic neuropathy (biomarker_via_orthology)

PCSK5 LRP1 FAS

1.77e-0399713DOID:11446 (biomarker_via_orthology)
DiseaseHeart valve disease

NOTCH1 COL1A1

1.79e-0326712C0018824
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2

1.79e-0326712DOID:1319 (implicated_via_orthology)
Diseasediabetes mellitus (implicated_via_orthology)

INSR LRP1

1.79e-0326712DOID:9351 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

NOTCH1 NOTCH2

1.79e-0326712C0334581
DiseaseProtoplasmic astrocytoma

NOTCH1 NOTCH2

1.79e-0326712C0334580
DiseaseFibrillary Astrocytoma

NOTCH1 NOTCH2

1.79e-0326712C0334582
DiseaseEndogenous Hyperinsulinism

FBN1 INSR

1.79e-0326712C1257963
DiseaseExogenous Hyperinsulinism

FBN1 INSR

1.79e-0326712C1257964
DiseaseCompensatory Hyperinsulinemia

FBN1 INSR

1.79e-0326712C1257965
DiseaseAnaplastic astrocytoma

NOTCH1 NOTCH2

1.93e-0327712C0334579
DiseaseLiver Cirrhosis

THBS1 FBN1 COL1A1

1.99e-03103713C0023890
Diseaseplatelet crit

VLDLR THBS1 TMPRSS6 AFF3 APOH ITGAD BRAP SORL1

2.01e-03952718EFO_0007985
DiseaseRetinitis Pigmentosa

EYS CRB1 RHO

2.04e-03104713C0035334
Diseaselung small cell carcinoma (is_implicated_in)

KMT2D LAMA3

2.07e-0328712DOID:5409 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
KEDVQDCGKVPDVCQ

AFF3

501

P51826
PVEENKCFECGVQEN

BRAP

311

Q7Z569
EDAQCIDGTIEVPKC

APOH

311

P02749
EQEDDVEGVCKPLSC

AZIN2

426

Q96A70
DIPKCGFDNEDPACN

NPR1

451

P16066
DLGCGVIQVDEDNCK

CASP8AP2

1761

Q9UKL3
DEERPGLQVDCVVCG

NR2F6

46

P10588
TGQKCETDVNECDIP

NOTCH2NLA

136

Q7Z3S9
ICCGKNPLGDDEASA

RHO

321

P08100
DKDGEGLSTQCECNI

DSG3

241

P32926
KSCEDVDECVGLQPV

FBLN7

266

Q53RD9
GQKCETDVNECDIPG

NOTCH2NLB

176

P0DPK3
GQKCETDVNECDIPG

NOTCH2

176

Q04721
VDECETEVCPGENKQ

CRELD1

306

Q96HD1
TEVCPGENKQCENTE

CRELD1

311

Q96HD1
GNSSECGQQPVVEKC

LARGE1

121

O95461
KGTTGPNCEINLDDC

NOTCH1

631

P46531
ECESNPCVNGGTCKD

NOTCH1

756

P46531
GDCTCKGENGEKDNI

MOV10L1

376

Q9BXT6
CTESDEGAKCQGEEN

MAGEB1

76

P43366
PGFKGTQCEIDIDEC

EYS

671

Q5T1H1
EDPVAGDIKGCDCNL

LAMA3

481

Q16787
CETKCVEPLGLENGN

MFGE8

66

Q08431
PSGKNCQDINECEEE

HMCN2

4896

Q8NDA2
VGATCQLDANECEGK

JAG2

416

Q9Y219
DEIPCNKTACGVGEF

LRP1

2596

Q07954
TVEGPCEAKIECSDN

FLNB

1076

O75369
TCQKLECGQGEVQDP

PCSK5

1016

Q92824
IEGSDCECNPAGKNF

PDE8B

751

O95263
GLTVEGPCEAKIECQ

FLNC

1096

Q14315
GPCEAKIECQDNGDG

FLNC

1101

Q14315
KEGDCKGCTVSPQVE

LAMA2

2321

P24043
KDDNEECGDICPGTA

INSR

176

P06213
TGQKCETDVNECDIP

NOTCH2NLC

136

P0DPK4
SLPFEKNCGQDGLCE

ITGAD

761

Q13349
CEDNRGPKGKCVDET

ITGB8

471

P26012
DGDCCDPQVADVRKT

PAPPA2

641

Q9BXP8
KVCELEEGFNCVGEP

PAPPA2

1141

Q9BXP8
CSDCNGEGEVINEKD

DNAJA2

186

O60884
DAPGSCVIDCNEKTG

ERVK-5

106

Q9HDB9
KEGELCCSEAGQRPE

CHD6

1786

Q8TD26
IDECEVFPGVCKNGL

FBN1

911

P35555
DIDECQELPGLCQGG

FBN1

1606

P35555
DIDECREIPGVCENG

FBN1

1766

P35555
GEGCVDENECQTKPG

FBN1

2286

P35555
DENECQTKPGICENG

FBN1

2291

P35555
QEQVHPKTGCECGDG

GAGE10

76

A6NGK3
LVDAGEECDCGTPKE

ADAM9

421

Q13443
GEPCGKTCLEERDNQ

ITGA4

111

P13612
DNDPIDVCEIGSKVC

PPA1

116

Q15181
ELTPDGKNCIDTNEC

FBN2

2006

P35556
PDGEGCVDENECRTK

FBN2

2331

P35556
KDIDECASDPCVNGG

CRB1

1296

P82279
PSEENSKDCVVCQNG

CGRRF1

266

Q99675
KGEGKQCEDIDECEN

SCUBE1

66

Q8IWY4
ECKEGLVCNGAPETE

MTMR3

921

Q13615
NEGIPDGACSKDSDC

P2RX5

121

Q93086
CLEGEECKTLPDNSG

TAFA1

101

Q7Z5A9
DGSDEDPVNCEKKCN

SORL1

1226

Q92673
KDNQEEGVCPICQES

TRIM40

6

Q6P9F5
CIGDEQGENKCVPNS

LTF

526

P02788
GEPVIKACIENGASC

SCCPDH

106

Q8NBX0
CVEIVKNDDGVIPCQ

TEC

61

P42680
GCDCCGEKSQPQEKS

RIF1

1731

Q5UIP0
VCKECEGRQEPASGG

EPHB6

406

O15197
DDVICDETKNCPGAE

COL1A1

71

P02452
CPVQDQACVAKFEDG

RNF17

726

Q9BXT8
EAGTVPEKEIFCQCG

SETDB2

696

Q96T68
GNGIQCTDVDECKEV

THBS1

581

P07996
AEPADCAEGPVQCKN

VSIG8

396

P0DPA2
NGDEPDCVPCQEGKE

FAS

76

P25445
CEEIPNPLKDGDCVN

MVK

161

Q03426
CKVDCEANLTPNVGG

P3H4

271

Q92791
PGLEGEQCEISKCPQ

WIF1

266

Q9Y5W5
CQKQGPPCSDSEEEV

RRP8

96

O43159
PTCDCVEQIVEKDEG

TET3

826

O43151
ETLEECKNICEDGPN

TFPI

166

P10646
CKNICEDGPNGFQVD

TFPI

171

P10646
ELIEGEANPCDICGK

ZNF623

116

O75123
PEAKSCDNFVCGEVG

ZNF763

101

Q0D2J5
EGKEPQKQLEGDCCS

UBR4

2606

Q5T4S7
EASQDGLGCVKCPEG

TG

1451

P01266
GVKDCPNGLDERNCV

TMPRSS6

476

Q8IU80
RKTCGDIDECQNPGI

VLDLR

391

P98155
ECKQTAGQGSPCEEQ

KMT2D

1171

O14686
DEVGCVNVTLCEGPN

LDLR

266

P01130