Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	GABRB1 GABRB3 GABRR1 OR2T29 OR10A7 OR8U1 GALR1 CHRNA9 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 GRM8 ADGRG4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 TAS2R45 LTB4R IL2RA MUSK	7.78e-08	1353	111	25	GO:0004888
GeneOntologyMolecularFunction	G protein-coupled receptor activity	GABRB1 OR2T29 OR10A7 OR8U1 GALR1 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 GRM8 ADGRG4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 TAS2R45 LTB4R	7.97e-08	884	111	20	GO:0004930
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 SLC38A4 SLC22A24 SLC9C2 MFSD12 OPRM1 SLC5A11 SLC7A8 SLC9C1 CACNA2D4 SLC9A3 CLCN7 CLCA2 SLC10A5 SCN3A SLC35F6 GPR89A SLC37A4 SLC9A6	1.11e-07	1180	111	23	GO:0022857
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 SLC38A4 SLC9C2 OPRM1 SLC5A11 SLC9C1 CACNA2D4 SLC9A3 CLCN7 CLCA2 SLC10A5 SCN3A GPR89A SLC9A6	3.69e-07	793	111	18	GO:0015075
GeneOntologyMolecularFunction	transporter activity	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 SLC38A4 SLC22A24 SLC9C2 MFSD12 OPRM1 SLC5A11 SLC7A8 SLC9C1 CACNA2D4 SLC9A3 CLCN7 CLCA2 SLC10A5 SCN3A SLC35F6 GPR89A SLC37A4 SLC9A6	5.29e-07	1289	111	23	GO:0005215
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC38A4 SLC9C2 MFSD12 SLC5A11 SLC7A8 SLC9C1 SLC9A3 CLCN7 SLC10A5 SLC37A4 SLC9A6	8.02e-07	296	111	11	GO:0015291
GeneOntologyMolecularFunction	potassium:proton antiporter activity	SLC9C2 SLC9C1 SLC9A3 SLC9A6	8.67e-07	14	111	4	GO:0015386
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRB1 GABRB3 GABRR1 CHRNA9 SLC38A4 SLC9C2 OPRM1 SLC5A11 SLC9C1 CACNA2D4 SLC9A3 CLCN7 CLCA2 SLC10A5 SCN3A SLC37A4 SLC9A6	9.54e-07	758	111	17	GO:0015318
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9C2 SLC9C1 SLC9A3 SLC9A6	1.56e-06	16	111	4	GO:0015385
GeneOntologyMolecularFunction	monoatomic anion channel activity	GABRB1 GABRB3 GPR89B GABRR1 CLCN7 CLCA2 GPR89A	1.73e-06	103	111	7	GO:0005253
GeneOntologyMolecularFunction	solute:potassium antiporter activity	SLC9C2 SLC9C1 SLC9A3 SLC9A6	3.29e-06	19	111	4	GO:0022821
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC38A4 SLC9C2 SLC5A11 SLC9C1 SLC9A3 SLC10A5 SCN3A SLC9A6	5.12e-06	171	111	8	GO:0015081
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 OPRM1 SLC9C1 CACNA2D4 CLCN7 CLCA2 SCN3A GPR89A	9.50e-06	459	111	12	GO:0005216
GeneOntologyMolecularFunction	antiporter activity	SLC9C2 SLC7A8 SLC9C1 SLC9A3 CLCN7 SLC37A4 SLC9A6	1.21e-05	138	111	7	GO:0015297
GeneOntologyMolecularFunction	metal cation:proton antiporter activity	SLC9C2 SLC9C1 SLC9A3 SLC9A6	1.44e-05	27	111	4	GO:0051139
GeneOntologyMolecularFunction	gated channel activity	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 OPRM1 CACNA2D4 CLCN7 CLCA2 GPR89A	1.73e-05	334	111	10	GO:0022836
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	GABRB1 GABRB3 GPR89B GABRR1 CLCN7 CLCA2 GPR89A	2.17e-05	151	111	7	GO:0008509
GeneOntologyMolecularFunction	channel activity	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 OPRM1 SLC9C1 CACNA2D4 CLCN7 CLCA2 SCN3A GPR89A	3.58e-05	525	111	12	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 OPRM1 SLC9C1 CACNA2D4 CLCN7 CLCA2 SCN3A GPR89A	3.64e-05	526	111	12	GO:0022803
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CHRNA9 SLC38A4 SLC9C2 OPRM1 SLC5A11 SLC9C1 CACNA2D4 SLC9A3 SLC10A5 SCN3A SLC9A6	5.66e-05	465	111	11	GO:0046873
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC38A4 SLC9C2 MFSD12 SLC5A11 SLC7A8 SLC9C1 SLC9A3 CLCN7 SLC10A5 SLC37A4 SLC9A6	7.11e-05	477	111	11	GO:0022804
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC9C2 SLC9C1 SLC9A3 SLC9A6	9.44e-05	43	111	4	GO:0140828
GeneOntologyMolecularFunction	voltage-gated monoatomic anion channel activity	GPR89B CLCN7 GPR89A	1.07e-04	17	111	3	GO:0008308
GeneOntologyMolecularFunction	chloride channel activity	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2	1.18e-04	86	111	5	GO:0005254
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRB1 GABRB3 GABRR1	1.28e-04	18	111	3	GO:0022851
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRB1 GABRB3 GABRR1	1.52e-04	19	111	3	GO:0004890
GeneOntologyMolecularFunction	ligand-gated monoatomic anion channel activity	GABRB1 GABRB3 GABRR1 CLCA2	1.71e-04	50	111	4	GO:0099095
GeneOntologyMolecularFunction	GABA receptor activity	GABRB1 GABRB3 GABRR1	2.38e-04	22	111	3	GO:0016917
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2 SLC37A4	3.89e-04	171	111	6	GO:0015103
GeneOntologyMolecularFunction	transmitter-gated channel activity	GABRB1 GABRB3 GABRR1 CHRNA9	4.72e-04	65	111	4	GO:0022835
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity	GABRB1 GABRB3 GABRR1 CHRNA9	4.72e-04	65	111	4	GO:0022824
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2	6.70e-04	125	111	5	GO:0015108
GeneOntologyMolecularFunction	olfactory receptor activity	OR2T29 OR10A7 OR8U1 OR1B1 OR2T5 OR2T4 OR8U8 OR52N2 OR4C13	6.78e-04	431	111	9	GO:0004984
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CHRNA9 SLC38A4 SLC9C2 OPRM1 SLC5A11 SLC9C1 CACNA2D4 SLC9A3 SLC10A5 SCN3A SLC9A6	7.40e-04	627	111	11	GO:0022890
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	GALR1 MCHR2 OPRM1 TACR2 LTB4R	8.86e-04	133	111	5	GO:0008528
GeneOntologyMolecularFunction	extracellular ligand-gated monoatomic ion channel activity	GABRB1 GABRB3 GABRR1 CHRNA9	8.96e-04	77	111	4	GO:0005230
GeneOntologyMolecularFunction	peptide receptor activity	GALR1 MCHR2 OPRM1 TACR2 LTB4R	1.11e-03	140	111	5	GO:0001653
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CHRNA9 SLC38A4 SLC9C2 OPRM1 SLC5A11 SLC9C1 CACNA2D4 SLC9A3 SLC10A5 SCN3A SLC9A6	1.18e-03	664	111	11	GO:0008324
GeneOntologyMolecularFunction	MAP kinase tyrosine phosphatase activity	DUSP7 DUSP8	1.34e-03	10	111	2	GO:0033550
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC38A4 SLC9C2 SLC5A11 SLC9C1 SLC9A3 SLC10A5 SLC9A6	1.47e-03	301	111	7	GO:0022853
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC38A4 MFSD12 SLC7A8	1.53e-03	41	111	3	GO:0015175
GeneOntologyMolecularFunction	protein tyrosine/threonine phosphatase activity	DUSP7 DUSP8	1.63e-03	11	111	2	GO:0008330
GeneOntologyMolecularFunction	MAP kinase tyrosine/serine/threonine phosphatase activity	DUSP7 DUSP8	2.29e-03	13	111	2	GO:0017017
GeneOntologyMolecularFunction	neurotransmitter receptor activity	GABRB1 GABRB3 GABRR1 CHRNA9	2.35e-03	100	111	4	GO:0030594
GeneOntologyMolecularFunction	neuropeptide receptor activity	GALR1 OPRM1 TACR2	3.20e-03	53	111	3	GO:0008188
GeneOntologyMolecularFunction	alanine transmembrane transporter activity	SLC38A4 SLC7A8	3.49e-03	16	111	2	GO:0022858
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	GPR89B OPRM1 CACNA2D4 CLCN7 GPR89A	3.50e-03	182	111	5	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	GPR89B OPRM1 CACNA2D4 CLCN7 GPR89A	3.67e-03	184	111	5	GO:0022832
GeneOntologyMolecularFunction	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	GABRB1 GABRB3 CHRNA9	3.93e-03	57	111	3	GO:1904315
GeneOntologyMolecularFunction	protein kinase B binding	TRAF6 RASA1	3.94e-03	17	111	2	GO:0043422
GeneOntologyMolecularFunction	MAP kinase phosphatase activity	DUSP7 DUSP8	4.42e-03	18	111	2	GO:0033549
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity	GABRB1 GABRB3 GABRR1 CHRNA9 CLCA2	4.49e-03	193	111	5	GO:0015276
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	GABRB1 GABRB3 CHRNA9	4.54e-03	60	111	3	GO:0099529
GeneOntologyMolecularFunction	ligand-gated channel activity	GABRB1 GABRB3 GABRR1 CHRNA9 CLCA2	4.90e-03	197	111	5	GO:0022834
GeneOntologyMolecularFunction	GABA receptor binding	GABRB1 PLCL2	5.45e-03	20	111	2	GO:0050811
GeneOntologyMolecularFunction	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	GABRB1 GABRR1	7.80e-03	24	111	2	GO:0099507
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR2T29 OR10A7 OR8U1 CHRNA9 OR1B1 BACE1 OR2T5 OR2T4 GRM8 OR8U8 CACNA2D4 OR52N2 OR4C13 TAS2R45	2.37e-06	582	109	14	GO:0050906
GeneOntologyBiologicalProcess	regulation of intracellular pH	GPR89B SLC9C2 SLC9C1 SLC9A3 GPR89A SLC9A6	1.06e-05	94	109	6	GO:0051453
GeneOntologyBiologicalProcess	sodium ion import across plasma membrane	SLC9C2 SLC9C1 SLC9A3 SLC9A6	1.18e-05	27	109	4	GO:0098719
GeneOntologyBiologicalProcess	regulation of cellular pH	GPR89B SLC9C2 SLC9C1 SLC9A3 GPR89A SLC9A6	1.60e-05	101	109	6	GO:0030641
GeneOntologyBiologicalProcess	monoatomic anion transmembrane transport	GABRB1 GABRB3 GPR89B GABRR1 CLCN7 CLCA2 GPR89A	1.70e-05	153	109	7	GO:0098656
GeneOntologyBiologicalProcess	detection of stimulus	OR2T29 OR10A7 OR8U1 CHRNA9 OR1B1 BACE1 OR2T5 OR2T4 GRM8 OR8U8 CACNA2D4 OR52N2 OR4C13 TAS2R45	2.71e-05	722	109	14	GO:0051606
GeneOntologyBiologicalProcess	monoatomic ion transport	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 SLC38A4 SLC22A24 SLC9C2 OPRM1 SLC5A11 SLC9C1 CACNA2D4 SLC9A3 CLCN7 CLCA2 SLC10A5 SCN3A GPR89A TACR2 SLC9A6	3.08e-05	1374	109	20	GO:0006811
GeneOntologyBiologicalProcess	gamma-aminobutyric acid signaling pathway	GABRB1 GABRB3 GABRR1 PLCL2	3.41e-05	35	109	4	GO:0007214
GeneOntologyBiologicalProcess	regulation of pH	GPR89B SLC9C2 SLC9C1 SLC9A3 GPR89A SLC9A6	4.25e-05	120	109	6	GO:0006885
GeneOntologyBiologicalProcess	sensory perception	OR2T29 OR10A7 OR8U1 CHRNA9 OR1B1 MYO7A BACE1 OR2T5 OR2T4 GRM8 OR8U8 OPRM1 CACNA2D4 OR52N2 HPS1 OR4C13 TAS2R45	4.60e-05	1072	109	17	GO:0007600
GeneOntologyBiologicalProcess	monoatomic anion transport	GABRB1 GABRB3 GPR89B GABRR1 CLCN7 CLCA2 GPR89A	5.37e-05	183	109	7	GO:0006820
GeneOntologyBiologicalProcess	inorganic anion transmembrane transport	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2 SLC37A4	7.87e-05	134	109	6	GO:0098661
GeneOntologyBiologicalProcess	sodium ion transport	SLC38A4 SLC9C2 SLC5A11 SLC9C1 SLC9A3 SLC10A5 SCN3A SLC9A6	1.07e-04	275	109	8	GO:0006814
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR2T29 OR10A7 OR8U1 GALR1 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 GRM8 ADGRG4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 TAS2R45 LTB4R	1.21e-04	1395	109	19	GO:0007186
GeneOntologyBiologicalProcess	L-alanine import across plasma membrane	SLC38A4 SLC7A8	1.65e-04	4	109	2	GO:1904273
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 SLC38A4 SLC9C2 OPRM1 SLC9C1 CACNA2D4 SLC9A3 CLCN7 CLCA2 SCN3A GPR89A SLC9A6	2.48e-04	1115	109	16	GO:0034220
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR2T29 OR10A7 OR8U1 OR1B1 OR2T5 OR2T4 OR8U8 OR52N2 OR4C13 TAS2R45	2.51e-04	485	109	10	GO:0050907
GeneOntologyBiologicalProcess	L-alanine transmembrane transport	SLC38A4 SLC7A8	2.74e-04	5	109	2	GO:1904557
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	GABRB1 GABRB3 GABRR1 CHRNA9 SLC38A4 SLC9C2 OPRM1 SLC9C1 CACNA2D4 SLC9A3 CLCN7 CLCA2 SCN3A SLC37A4 SLC9A6	2.94e-04	1017	109	15	GO:0098660
GeneOntologyBiologicalProcess	chloride transmembrane transport	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2	3.22e-04	112	109	5	GO:1902476
GeneOntologyBiologicalProcess	inorganic anion transport	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2 SLC37A4	3.91e-04	180	109	6	GO:0015698
GeneOntologyBiologicalProcess	negative regulation of luteinizing hormone secretion	OPRM1 TACR2	4.09e-04	6	109	2	GO:0033685
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR2T29 OR10A7 OR8U1 OR1B1 OR2T5 OR2T4 OR8U8 OR52N2 OR4C13 TAS2R45	4.62e-04	524	109	10	GO:0009593
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR2T29 OR10A7 OR8U1 OR1B1 OR2T5 OR2T4 OR8U8 OR52N2 OR4C13	4.80e-04	432	109	9	GO:0050911
GeneOntologyBiologicalProcess	cellular response to histamine	GABRB1 GABRB3	5.71e-04	7	109	2	GO:0071420
GeneOntologyBiologicalProcess	chloride transport	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2	5.94e-04	128	109	5	GO:0006821
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR2T29 OR10A7 OR8U1 OR1B1 OR2T5 OR2T4 OR8U8 OR52N2 OR4C13 TAS2R45	6.45e-04	547	109	10	GO:0007606
GeneOntologyCellularComponent	GABA-A receptor complex	GABRB1 GABRB3 GABRR1	1.29e-04	19	110	3	GO:1902711
GeneOntologyCellularComponent	monoatomic ion channel complex	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 CACNA2D4 CLCN7 SCN3A GPR89A	1.75e-04	378	110	9	GO:0034702
GeneOntologyCellularComponent	GABA receptor complex	GABRB1 GABRB3 GABRR1	1.76e-04	21	110	3	GO:1902710
GeneOntologyCellularComponent	chloride channel complex	GABRB1 GABRB3 GABRR1 CLCN7	2.31e-04	57	110	4	GO:0034707
GeneOntologyCellularComponent	transporter complex	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 ERGIC2 CACNA2D4 CLCN7 SCN3A GPR89A	6.52e-04	550	110	10	GO:1990351
GeneOntologyCellularComponent	vacuole	MYO7A ACLY BACE1 RNF13 FYCO1 RB1CC1 MFSD12 TMBIM1 CLCN7 MAP1LC3C HPS1 SLC35F6 NKG7	1.02e-03	913	110	13	GO:0005773
GeneOntologyCellularComponent	lysosome	MYO7A ACLY BACE1 RNF13 FYCO1 RB1CC1 MFSD12 TMBIM1 CLCN7 HPS1 SLC35F6 NKG7	1.16e-03	811	110	12	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	MYO7A ACLY BACE1 RNF13 FYCO1 RB1CC1 MFSD12 TMBIM1 CLCN7 HPS1 SLC35F6 NKG7	1.16e-03	811	110	12	GO:0000323
GeneOntologyCellularComponent	vacuolar membrane	MYO7A RNF13 RB1CC1 MFSD12 TMBIM1 CLCN7 MAP1LC3C SLC35F6 NKG7	1.44e-03	507	110	9	GO:0005774
GeneOntologyCellularComponent	GABA-ergic synapse	GABRB1 GABRB3 GABRR1 GRM8 OPRM1	1.76e-03	164	110	5	GO:0098982
GeneOntologyCellularComponent	transmembrane transporter complex	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 CACNA2D4 CLCN7 SCN3A GPR89A	1.78e-03	523	110	9	GO:1902495
Domain	Cation/H_exchanger_CPA1	SLC9C2 SLC9C1 SLC9A3 SLC9A6	3.38e-07	11	108	4	IPR018422
Domain	Na_H_Exchanger	SLC9C2 SLC9C1 SLC9A3 SLC9A6	1.01e-06	14	108	4	PF00999
Domain	Cation/H_exchanger	SLC9C2 SLC9C1 SLC9A3 SLC9A6	1.01e-06	14	108	4	IPR006153
Domain	GPCR_Rhodpsn_7TM	OR2T29 OR10A7 OR8U1 GALR1 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 LTB4R	1.49e-06	670	108	16	IPR017452
Domain	7tm_1	OR2T29 OR10A7 OR8U1 GALR1 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 LTB4R	1.70e-06	677	108	16	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR2T29 OR10A7 OR8U1 GALR1 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 LTB4R	1.98e-06	685	108	16	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2T29 OR10A7 OR8U1 GALR1 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 LTB4R	2.22e-06	691	108	16	PS50262
Domain	GPCR_Rhodpsn	OR2T29 OR10A7 OR8U1 GALR1 OR1B1 MCHR2 P2RY8 OR2T5 OR2T4 OR8U8 OPRM1 LPAR6 OR52N2 OR4C13 TACR2 LTB4R	2.26e-06	692	108	16	IPR000276
Domain	GABAAb_rcpt	GABRB1 GABRB3	9.90e-05	3	108	2	IPR002289
Domain	Neurotransmitter_ion_chnl_CS	GABRB1 GABRB3 GABRR1 CHRNA9	1.31e-04	45	108	4	IPR018000
Domain	Neur_chan_memb	GABRB1 GABRB3 GABRR1 CHRNA9	1.43e-04	46	108	4	PF02932
Domain	Neur_chan_LBD	GABRB1 GABRB3 GABRR1 CHRNA9	1.56e-04	47	108	4	PF02931
Domain	NEUROTR_ION_CHANNEL	GABRB1 GABRB3 GABRR1 CHRNA9	1.56e-04	47	108	4	PS00236
Domain	Neurotrans-gated_channel_TM	GABRB1 GABRB3 GABRR1 CHRNA9	1.56e-04	47	108	4	IPR006029
Domain	-	GABRB1 GABRB3 GABRR1 CHRNA9	1.56e-04	47	108	4	2.70.170.10
Domain	Neur_channel	GABRB1 GABRB3 GABRR1 CHRNA9	1.56e-04	47	108	4	IPR006201
Domain	Neur_chan_lig-bd	GABRB1 GABRB3 GABRR1 CHRNA9	1.56e-04	47	108	4	IPR006202
Domain	GABAA/Glycine_rcpt	GABRB1 GABRB3 GABRR1	3.06e-04	23	108	3	IPR006028
Domain	Olfact_rcpt	OR2T29 OR10A7 OR8U1 OR1B1 OR2T5 OR2T4 OR8U8 OR52N2 OR4C13	4.61e-04	393	108	9	IPR000725
Domain	ENTH	EPN2 EPN1	4.89e-04	6	108	2	PF01417
Domain	Bax_inhibitor_1-related	GRINA TMBIM1	4.89e-04	6	108	2	IPR006214
Domain	ENTH	EPN2 EPN1	1.16e-03	9	108	2	PS50942
Domain	NaH_exchanger	SLC9A3 SLC9A6	1.16e-03	9	108	2	IPR004709
Domain	ENTH	EPN2 EPN1	1.16e-03	9	108	2	SM00273
Domain	MKP	DUSP7 DUSP8	1.45e-03	10	108	2	IPR008343
Domain	ENTH	EPN2 EPN1	1.45e-03	10	108	2	IPR013809
Domain	EamA_dom	SLC35G2 SLC35F6	2.88e-03	14	108	2	IPR000620
Domain	EamA	SLC35G2 SLC35F6	2.88e-03	14	108	2	PF00892
Domain	VWA	PARP4 CACNA2D4 CLCA2	4.17e-03	56	108	3	PF00092
Domain	UIM	EPN2 EPN1	4.77e-03	18	108	2	PF02809
Domain	BRCT	TOPBP1 PARP4	5.31e-03	19	108	2	PF00533
Pathway	KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION	GABRB1 GABRB3 GABRR1 GALR1 CHRNA9 MCHR2 P2RY8 GRM8 OPRM1 LPAR6 TACR2 LTB4R	1.17e-07	272	88	12	M13380
Pubmed	Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.	GABRB1 GABRB3 GABRR1 GALR1 GRM8 OPRM1 TACR2	7.97e-09	81	111	7	22723691
Pubmed	ATG8 family proteins act as scaffolds for assembly of the ULK complex: sequence requirements for LC3-interacting region (LIR) motifs.	FYCO1 RB1CC1 MAP1LC3C	5.12e-06	11	111	3	23043107
Pubmed	GABAA receptors involved in sleep and anaesthesia: β1- versus β3-containing assemblies.	GABRB1 GABRB3	1.01e-05	2	111	2	21735059
Pubmed	Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function.	GABRB1 GABRB3	1.01e-05	2	111	2	26950270
Pubmed	Multiple modes for conferring surface expression of homomeric beta1 GABAA receptors.	GABRB1 GABRB3	1.01e-05	2	111	2	18650446
Pubmed	Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.	GALR1 OPRM1	1.01e-05	2	111	2	28007761
Pubmed	The murine choroid plexus epithelium expresses the 2Cl-/H+ exchanger ClC-7 and Na+/H+ exchanger NHE6 in the luminal membrane domain.	CLCN7 SLC9A6	1.01e-05	2	111	2	29351414
Pubmed	GPHR-dependent functions of the Golgi apparatus are essential for the formation of lamellar granules and the skin barrier.	GPR89B GPR89A	1.01e-05	2	111	2	22572823
Pubmed	Curvature of clathrin-coated pits driven by epsin.	EPN2 EPN1	1.01e-05	2	111	2	12353027
Pubmed	Ptchd1 mediates opioid tolerance via cholesterol-dependent effects on μ-opioid receptor trafficking.	OPRM1 PTCHD1	1.01e-05	2	111	2	35982154
Pubmed	GPHR is a novel anion channel critical for acidification and functions of the Golgi apparatus.	GPR89B GPR89A	1.01e-05	2	111	2	18794847
Pubmed	Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.	GABRB1 GABRB3 GABRR1	2.49e-05	18	111	3	19078961
Pubmed	Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling.	EPN2 EPN1	3.02e-05	3	111	2	34440686
Pubmed	A mammalian mirtron miR-1224 promotes tube-formation of human primary endothelial cells by targeting anti-angiogenic factor epsin2.	EPN2 EPN1	3.02e-05	3	111	2	28717225
Pubmed	Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development.	EPN2 EPN1	3.02e-05	3	111	2	32960814
Pubmed	Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function.	GPR89B GPR89A	3.02e-05	3	111	2	32220963
Pubmed	Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.	GABRB1 GABRB3	3.02e-05	3	111	2	18281286
Pubmed	Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.	EPN2 EPN1	3.02e-05	3	111	2	23187125
Pubmed	[Functional Hypermethylation of ALDH1L1, PLCL2, and PPP2R3A in Colon Cancer].	PPP2R3A PLCL2	3.02e-05	3	111	2	32392189
Pubmed	GABAA receptor beta 1, beta 2, and beta 3 subunits: comparisons in DBA/2J and C57BL/6J mice.	GABRB1 GABRB3	3.02e-05	3	111	2	7893750
Pubmed	Expression and distribution of GABAA receptor subtypes in human alcoholic cerebral cortex.	GABRB1 GABRB3	3.02e-05	3	111	2	11085308
Pubmed	GABAA receptor beta subunit mRNA expression in the human alcoholic brain.	GABRB1 GABRB3	3.02e-05	3	111	2	15337300
Pubmed	Differential expression of GABAA/benzodiazepine receptor beta 1, beta 2, and beta 3 subunit mRNAs in the developing mouse cerebellum.	GABRB1 GABRB3	3.02e-05	3	111	2	1282920
Pubmed	Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma.	ALCAM PRKDC	3.02e-05	3	111	2	27634757
Pubmed	Integral and associated lysosomal membrane proteins.	RNF13 MFSD12 TMBIM1 CLCN7 SLC35F6	5.43e-05	126	111	5	17897319
Pubmed	Genetic reduction of vascular endothelial growth factor receptor 2 rescues aberrant angiogenesis caused by epsin deficiency.	EPN2 EPN1	6.03e-05	4	111	2	24311377
Pubmed	Retinoic-acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation.	PRKDC IL2RA	6.03e-05	4	111	2	22981535
Pubmed	The epsin family of endocytic adaptors promotes fibrosarcoma migration and invasion.	EPN2 EPN1	6.03e-05	4	111	2	20709745
Pubmed	T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells.	PRKDC IL2RA	6.03e-05	4	111	2	15753207
Pubmed	Epsin-mediated degradation of IP3R1 fuels atherosclerosis.	EPN2 EPN1	6.03e-05	4	111	2	32770009
Pubmed	Cerebellar Neurodegeneration and Neuronal Circuit Remodeling in Golgi pH Regulator-Deficient Mice.	GPR89B GPR89A	6.03e-05	4	111	2	31118204
Pubmed	Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.	TRAF6 PRKDC	6.03e-05	4	111	2	23791643
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	IFT140 ATXN7L1 TOPBP1 CTR9 PLCL2	6.30e-05	130	111	5	12421765
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR2T29 OR2T5 OR2T4 OR52N2	9.52e-05	74	111	4	15081110
Pubmed	Muscle-like nicotinic receptor accessory molecules in sensory hair cells of the inner ear.	CHRNA9 MUSK	1.00e-04	5	111	2	18420419
Pubmed	Genotype patterns that contribute to increased risk for or protection from developing heroin addiction.	GRM8 OPRM1	1.00e-04	5	111	2	18195715
Pubmed	The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors.	GABRB1 GABRB3	1.00e-04	5	111	2	15198677
Pubmed	A-kinase anchoring protein 79/150 facilitates the phosphorylation of GABA(A) receptors by cAMP-dependent protein kinase via selective interaction with receptor beta subunits.	GABRB1 GABRB3	1.00e-04	5	111	2	12595241
Pubmed	Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit.	GABRB1 GABRB3	1.00e-04	5	111	2	9039914
Pubmed	Intersectin, a novel adaptor protein with two Eps15 homology and five Src homology 3 domains.	EPN2 EPN1	1.00e-04	5	111	2	9813051
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2T29 OR8U1 OR1B1 OR2T5 OR2T4 OR52N2 OR4C13	1.14e-04	340	111	7	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2T29 OR8U1 OR1B1 OR2T5 OR2T4 OR52N2 OR4C13	1.14e-04	340	111	7	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2T29 OR8U1 OR1B1 OR2T5 OR2T4 OR52N2 OR4C13	1.21e-04	343	111	7	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2T29 OR8U1 OR1B1 OR2T5 OR2T4 OR52N2 OR4C13	1.27e-04	346	111	7	14611657
Pubmed	Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma in a pooled analysis of three studies.	TRAF6 GPX3 PRKDC	1.33e-04	31	111	3	20813000
Pubmed	Comparative genomics and function analysis on BI1 family.	GRINA TMBIM1	1.50e-04	6	111	2	18440869
Pubmed	Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells.	P2RY8 LPAR6	1.50e-04	6	111	2	11004484
Pubmed	Evolution of GABA(A) receptor diversity in the human genome.	GABRB1 GABRB3	1.50e-04	6	111	2	10023064
Pubmed	The GABAA Receptor β Subunit Is Required for Inhibitory Transmission.	GABRB1 GABRB3	1.50e-04	6	111	2	29706582
Pubmed	Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.	EPN2 EPN1	1.50e-04	6	111	2	25122462
Pubmed	Response to methadone maintenance treatment is associated with the MYOCD and GRM6 genes.	GRM8 OPRM1	1.50e-04	6	111	2	20560679
Pubmed	Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes.	EPN2 EPN1	1.50e-04	6	111	2	30102256
Pubmed	The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.	GRINA TMBIM1	1.50e-04	6	111	2	25764978
Pubmed	Epsin is required for Dishevelled stability and Wnt signalling activation in colon cancer development.	EPN2 EPN1	1.50e-04	6	111	2	25871009
Pubmed	The ubiquitin-like protein PLIC-2 is a negative regulator of G protein-coupled receptor endocytosis.	EPN2 EPN1	2.10e-04	7	111	2	18199683
Pubmed	Gene expression profiling of arthritis using a QTL chip reveals a complex gene regulation of the Cia5 region in mice.	GPR89B GPR89A	2.10e-04	7	111	2	16015370
Pubmed	Lamina-specific alterations in cortical GABA(A) receptor subunit expression in schizophrenia.	GABRB1 GABRB3	2.10e-04	7	111	2	20843900
Pubmed	Modulation of GABA(A) receptor phosphorylation and membrane trafficking by phospholipase C-related inactive protein/protein phosphatase 1 and 2A signaling complex underlying brain-derived neurotrophic factor-dependent regulation of GABAergic inhibition.	GABRB3 PLCL2	2.10e-04	7	111	2	16754670
Pubmed	Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.	GABRB3 SLC38A4 LDAF1 RNF13 SLC35G2 C3P1 SMPDL3B ALCAM	2.39e-04	510	111	8	16712791
Pubmed	Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.	GPR89B TRAF6 GRINA GPR89A	2.40e-04	94	111	4	12761501
Pubmed	Stable association between G alpha(q) and phospholipase C beta 1 in living cells.	MCHR2 LPAR6 TACR2 LTB4R	2.50e-04	95	111	4	16754659
Pubmed	mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.	TRAF6 RB1CC1	2.79e-04	8	111	2	23524951
Pubmed	Structural basis of the autophagy-related LC3/Atg13 LIR complex: recognition and interaction mechanism.	RB1CC1 MAP1LC3C	2.79e-04	8	111	2	24290141
Pubmed	GABA(A) receptor cell surface number and subunit stability are regulated by the ubiquitin-like protein Plic-1.	GABRB1 GABRB3	2.79e-04	8	111	2	11528422
Pubmed	Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV.	MYO7A HPS1	2.79e-04	8	111	2	15702992
Pubmed	Association study of 182 candidate genes in anorexia nervosa.	GABRB1 GABRB3 GABRR1 GALR1 OPRM1	3.04e-04	182	111	5	20468064
Pubmed	Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.	GABRB1 GABRB3 GPR89B TRAF6 DOCK8 PTCHD1 GPR89A	3.17e-04	402	111	7	24722188
Pubmed	Inhibition of tumor angiogenesis and growth by a small-molecule multi-FGF receptor blocker with allosteric properties.	GALR1 OPRM1 TACR2	3.56e-04	43	111	3	23597562
Pubmed	Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function.	EPN2 EPN1	3.58e-04	9	111	2	25314967
Pubmed	A growing family of dual specificity phosphatases with low molecular masses.	DUSP7 DUSP8	3.58e-04	9	111	2	11432789
Pubmed	Identification of novel genetic loci for bone size and mechanosensitivity in an ENU mutant exhibiting decreased bone size.	GABRR1 MUSK	3.58e-04	9	111	2	15883645
Pubmed	Congenital Diaphragmatic Hernia Overview	PIGN FREM2 MYRF	4.35e-04	46	111	3	20301533
Pubmed	Eleven densely clustered genes, six of them novel, in 176 kb of mouse t-complex DNA.	IFT140 CRAMP1	4.47e-04	10	111	2	10899141
Pubmed	Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.	MYO7A DUSP7 DUSP8	4.93e-04	48	111	3	30938680
Pubmed	A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.	OR2T29 ATXN7L1 DUSP8 OR2T5 OR2T4	5.24e-04	205	111	5	12040188
Pubmed	Methods for Studying Interactions Between Atg8/LC3/GABARAP and LIR-Containing Proteins.	RB1CC1 MAP1LC3C	5.45e-04	11	111	2	28253953
Pubmed	SARM1 and TRAF6 bind to and stabilize PINK1 on depolarized mitochondria.	TRAF6 RB1CC1	5.45e-04	11	111	2	23885119
Pubmed	Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.	GABRB1 CHRNA9	5.45e-04	11	111	2	17698926
Pubmed	A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).	PDS5B TRAF6 RHOT1	5.89e-04	51	111	3	28185240
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	LDAF1 ERGIC2 RB1CC1 EPN2 CLCN7 SLC35F6 GPR89A PRKDC EPN1 MYRF SLC37A4	5.95e-04	1061	111	11	33845483
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	RASA1 SCN3A	6.52e-04	12	111	2	8169823
Pubmed	Chromosomal localization of opioid peptide and receptor genes in the mouse.	GABRR1 OPRM1	6.52e-04	12	111	2	7752808
Pubmed	XIAP and PHB1 Regulate Anoikis through Competitive Binding to TRAF6.	TRAF6 ACLY	6.52e-04	12	111	2	36346305
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	DOCK8 EPN2 PARP4 CLCN7	7.08e-04	125	111	4	29467281
Pubmed	Massively parallel sequencing of the mouse exome to accurately identify rare, induced mutations: an immediate source for thousands of new mouse models.	PRKDC KLRG1	7.69e-04	13	111	2	22724066
Pubmed	Intrinsically Disordered Protein TEX264 Mediates ER-phagy.	FYCO1 RB1CC1 MAP1LC3C CTR9	8.43e-04	131	111	4	31006538
Pubmed	A multivariate analysis of 59 candidate genes in personality traits: the temperament and character inventory.	GABRB1 GABRB3 OPRM1	8.59e-04	58	111	3	11140838
Pubmed	Pigmentation-related genes and their implication in malignant melanoma susceptibility.	MYO7A HPS1	8.96e-04	14	111	2	19320733
Pubmed	The biochemical anatomy of cortical inhibitory synapses.	GABRB1 GABRB3	8.96e-04	14	111	2	22768092
Pubmed	NIMA-related kinase 9-mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1.	FYCO1 MAP1LC3C	8.96e-04	14	111	2	31857374
Pubmed	Mouse chromosomal location of four Na/H exchanger isoform genes.	RASA1 SLC9A3	8.96e-04	14	111	2	8824815
Pubmed	Mutations in mice that influence natural killer (NK) cell activity.	MFSD12 HPS1	8.96e-04	14	111	2	6971254
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	BACE1 RB1CC1 CACNA2D4 CLCN7 MYRF	9.31e-04	233	111	5	32290105
Pubmed	GIAT4RA functions as a tumor suppressor in non-small cell lung cancer by counteracting Uchl3-mediated deubiquitination of LSH.	ACLY PRKDC	1.03e-03	15	111	2	31417184
Pubmed	Iris phenotypes and pigment dispersion caused by genes influencing pigmentation.	MYO7A HPS1	1.03e-03	15	111	2	18715234
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	GPR89B IFT140 CNOT11 TRAF6 MYO7A PSMB1 CHORDC1 EPN2 SLC9C1 CTR9 PLCL2 SLC35F6	1.06e-03	1321	111	12	27173435
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	ERGIC2 MFSD12 FREM2 PARP4 ARAP3 CTR9 EPN1 RHOT1	1.17e-03	650	111	8	38777146
Pubmed	Defining the membrane proteome of NK cells.	PPP1R21 PIGN DOCK8 ACLY FYCO1 ERGIC2 PARP4 CLCN7 PRKDC SLC37A4 RHOT1	1.30e-03	1168	111	11	19946888
Pubmed	The epsins define a family of proteins that interact with components of the clathrin coat and contain a new protein module.	EPN2 EPN1	1.49e-03	18	111	2	10567358
Pubmed	GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.	GABRB1 GABRB3	1.49e-03	18	111	2	18985723
Cytoband	8q11	RB1CC1 PRKDC	8.48e-05	6	110	2	8q11
GeneFamily	Solute carriers	SLC38A4 SLC35G2 SLC22A24 SLC9C2 SLC5A11 SLC7A8 SLC9C1 SLC9A3 SLC10A5 SLC37A4 SLC9A6	1.28e-06	395	80	11	752
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRB1 GABRB3 GABRR1	7.68e-05	19	80	3	563
GeneFamily	Transmembrane BAX inhibitor motif containing	GRINA TMBIM1	2.87e-04	6	80	2	1215
GeneFamily	MAP kinase phosphatases	DUSP7 DUSP8	1.04e-03	11	80	2	895
Coexpression	GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_UP	GPR89B ACLY PSMB1 DUSP7 ERGIC2 FANCE CTR9 ALCAM	1.53e-06	199	106	8	M7041
Coexpression	GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_DN	GRINA SLC7A8 SMPDL3B CLCN7 PLCL2 SLC35F6 ZBTB10	1.75e-05	200	106	7	M7822
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CNOT11 DOCK8 FANCE ARAP3 PLCL2 PRKDC	1.97e-06	151	109	6	b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 SLC7A8 SLC9C1 PPP2R3A MYRF SLC37A4	4.93e-06	177	109	6	9c7c6824b9011363851f084a500d665f025b026e
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP8 GPX3 SLC7A8 PTCHD1 SCN3A KLRG1	4.93e-06	177	109	6	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX3 SLC7A8 SLC9C1 PPP2R3A MYRF SLC37A4	4.93e-06	177	109	6	2bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP8 GPX3 SLC7A8 PTCHD1 SCN3A KLRG1	4.93e-06	177	109	6	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 P2RY8 OPRM1 PLCL2 IL2RA KLRG1	9.91e-06	200	109	6	cded40d5069a6fdbd90ac9a2a0bbef11727b28d5
ToppCell	droplet-Heart-HEART-1m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IFT140 DOCK8 SLC7A8 SMPDL3B ALCAM	1.53e-05	127	109	5	983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCell	3'_v3-blood-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM\|blood / Manually curated celltypes from each tissue	SLC35G2 FANCE MAP1LC3C NKG7 KLRG1	2.28e-05	138	109	5	9f8389a34c400a6b2b9bf6cef3a71499cc945e35
ToppCell	367C-Lymphocytic-CD4_T-cell-Treg_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	PGM2L1 SLC7A8 PTCHD1 CLCA2 IL2RA	3.63e-05	152	109	5	6d02b50e9e9ecf820f84a79e46d153a4840a1cfe
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPRC1 GPX3 BACE1 PPP2R3A SLC37A4	4.11e-05	156	109	5	5b2781d38a83b4b0f8a53cf321ce5db3a07d0818
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPRC1 GPX3 BACE1 PPP2R3A SLC37A4	4.11e-05	156	109	5	e0aef6104be16b12304b8e30358f444c1660e92f
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK8 WDR25 NKG7 RNF139 KLRG1	4.63e-05	160	109	5	b2d8940ea8c068273b7da1589d3d6ae5110d8209
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPOLB PGM2L1 OPRM1 NKG7 KLRG1	4.63e-05	160	109	5	398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK8 WDR25 NKG7 RNF139 KLRG1	4.63e-05	160	109	5	9caab1bb63c7e66c44783852ee75b16bb40fa594
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAPOLB PGM2L1 OPRM1 NKG7 KLRG1	4.63e-05	160	109	5	12aaab0291035f578e2433efd169ae72f393a5a5
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK8 WDR25 NKG7 RNF139 KLRG1	4.63e-05	160	109	5	229841be7b984a00a301cd5d88c11226a90d8a88
ToppCell	E16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK8 WDR25 NKG7 RNF139 KLRG1	4.63e-05	160	109	5	99c9ae2041445539fada842e1af01368669bfca0
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	P2RY8 SCN3A NKG7 CARNMT1 KLRG1	4.77e-05	161	109	5	d72c572613f8eff3251cb7b1e9dcc76d193b2f21
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PEX11G DUSP8 MCHR2 P2RY8 ZBTB10	4.91e-05	162	109	5	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	P2RY8 SLC9A3 NKG7 CARNMT1 KLRG1	5.06e-05	163	109	5	13f76f2979558f5cd27fbfd1659b413b3cac18f5
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LPAR6 NKG7 LTB4R IL2RA KLRG1	5.36e-05	165	109	5	004d793bf5bb6fb3b7bf38baf11b32d46375fe4d
ToppCell	facs-Heart-RV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A11 NKG7 LTB4R IL2RA KLRG1	5.52e-05	166	109	5	c0fd3f3f5c3412746da279b856af0d28b9b70c5d
ToppCell	facs-Heart-RV-3m-Lymphocytic\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A11 NKG7 LTB4R IL2RA KLRG1	5.52e-05	166	109	5	33c4876df43b4c1d100699bca47459918bd054d6
ToppCell	facs-Heart-RV-3m-Lymphocytic-T_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC5A11 NKG7 LTB4R IL2RA KLRG1	5.52e-05	166	109	5	ac9b9df57d65ccbbf9ae3add50c5663efcd30dcb
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB1 GPX3 SLC35G2 PTCHD1 CACNA2D4	6.01e-05	169	109	5	7be742160e3e7e6c8f86b037be4e425f4d4cf663
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRB1 GPX3 SLC35G2 PTCHD1 CACNA2D4	6.01e-05	169	109	5	4ccf5cfa4fe72d3af056d658460a9ccaa07b01be
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A GPX3 SLC5A11 NKG7 LTB4R	6.35e-05	171	109	5	dca4aa921896ec935fb7acdf25a62d8eba679602
ToppCell	droplet-Kidney-KIDNEY-1m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDS5B MBOAT1 DOCK8 TMBIM1 SMPDL3B	6.35e-05	171	109	5	d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCell	facs-Marrow-Granulocytes-24m-Myeloid-granulocyte_monocyte_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7A GPX3 SLC5A11 NKG7 LTB4R	6.35e-05	171	109	5	add2f7d34889ec654b8c71b4b1f084736111dc88
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LDAF1 GRM8 ADAMTS12 SLC9C1 ALCAM	6.71e-05	173	109	5	b002b22f9968b5967d29fe0eab4e796d87b355fa
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GABRB3 GALR1 ADGRG4 GREB1L SCN3A	6.89e-05	174	109	5	a62531ebf16b32b249168dca11b870f63a8aa81c
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 GPX3 MFSD12 SLC10A5 ALCAM	7.08e-05	175	109	5	0992de1c7bffcb6890584357a7a0a8955927da6c
ToppCell	facs-MAT-Fat-3m-Lymphocytic-T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 SLC7A8 LTB4R IL2RA KLRG1	7.28e-05	176	109	5	71b3309ddadd035a1224fca4fc5946dc4c0283fe
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRR1 GPX3 SLC35G2 GRM8 SCN3A	8.09e-05	180	109	5	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	facs-GAT-Fat-3m-Lymphocytic-T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 PGM2L1 LTB4R IL2RA KLRG1	8.52e-05	182	109	5	751bd3e3b49de961523e98197688a05c998c121a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GALR1 SLC38A4 GREB1L SCN3A PLCL2	8.75e-05	183	109	5	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	E15.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FREM2 TACR2 ALCAM FLRT1 MYRF	8.75e-05	183	109	5	274f274cf60daa30d6a4cd603a3af7823bfb8016
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	DOCK8 P2RY8 OPRM1 PLCL2 KLRG1	9.20e-05	185	109	5	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_early\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CHRNA9 MCHR2 GRM8 FREM2 SMPDL3B	1.02e-04	189	109	5	a6c62b456982067ad4d224a2efa3919969000693
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 GREB1L SLC9C1 SCN3A PLCL2	1.02e-04	189	109	5	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MBOAT1 PEX11G GPX3 CTR9 ALCAM	1.07e-04	191	109	5	b94e66ac71e73f46b0323d424e7b8b906751d584
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MBOAT1 GREB1L SCN3A PLCL2 MYRF	1.10e-04	192	109	5	0bb06738e1c3ec0c044a7ee61f6cf1d4781fb53c
ToppCell	Tracheal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MYO7A DOCK8 P2RY8 NKG7 IL2RA	1.24e-04	197	109	5	9791923feefbd78810242113ad2a08ce4c2bb4f2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	GABRB1 GABRB3 PGM2L1 PTCHD1 SCN3A	1.24e-04	197	109	5	4961f66606f08e399508fd6cabca588e7ab406a8
ToppCell	proximal-Epithelial-Neuroendocrine\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GABRB1 GABRR1 GALR1 GRM8 SCN3A	1.27e-04	198	109	5	5dea6078488d584513c0bdbf5bba54877310b54a
ToppCell	proximal-Epithelial-Neuroendocrine-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GABRB1 GABRR1 GALR1 GRM8 SCN3A	1.27e-04	198	109	5	00ccf3020667cf2130bc354b441b65c0b1b0e862
ToppCell	proximal-3-Epithelial-Neuroendocrine\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GABRB1 GABRR1 GALR1 GRM8 SCN3A	1.27e-04	198	109	5	a6bc043faf68468d46bac441cf7447c236c7bae4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GALR1 GREB1L FREM2 PLCL2 MYRF	1.27e-04	198	109	5	0d9d401190792fd61434f1b82548253187d805f0
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RIN3 DOCK8 P2RY8 PLCL2 NKG7	1.30e-04	199	109	5	7d69785717073491b5fb81bf24db0175f86cd0b0
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 P2RY8 PLCL2 NKG7 KLRG1	1.30e-04	199	109	5	eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_GZMK+\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	P2RY8 OPRM1 PLCL2 NKG7 KLRG1	1.33e-04	200	109	5	7a9c3f51d4a8fda5f1b7e0be6fcf9c1c92fffe99
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-BMP_responsible_cell\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	RIN3 DOCK8 TMBIM1 SLC7A8 LPAR6	1.33e-04	200	109	5	cd0d69f973ca3204b500d12031b403a1f4593431
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	GPX3 RNF13 SLC7A8 LPAR6 ALCAM	1.33e-04	200	109	5	195862a319794e57f0506757ae45ab70200bc5b4
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	RIN3 DOCK8 DUSP7 SLC7A8 LPAR6	1.33e-04	200	109	5	fe22f7c97f4e37dfa7881d0f1d9245c1237d873b
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 P2RY8 PLCL2 IL2RA KLRG1	1.33e-04	200	109	5	e0cec0a844b7c1f8edee4c005af27766754e470a
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 P2RY8 OPRM1 PLCL2 KLRG1	1.33e-04	200	109	5	c6c2b39359c65c9444987d02d1c899dff2ad1366
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	RIN3 DOCK8 TMBIM1 SLC7A8 LPAR6	1.33e-04	200	109	5	16caefcc5bdca82d904462c6fd0ffa80d96fa474
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK8 P2RY8 OPRM1 PLCL2 KLRG1	1.33e-04	200	109	5	66fb892bda1d29e67a65717e85f2ec221f520b2a
ToppCell	Lung_Parenchyma-Control\|Lung_Parenchyma / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DOCK8 GPX3 RNF13 TMBIM1 ALCAM	1.33e-04	200	109	5	2cb0fba2477d885b62850e473b4b637a5af531a9
Drug	AC1Q3ZOL	GABRB1 GABRB3 GABRR1 CNOT11 CHRNA9 GRINA GRM8 OPRM1 CACNA2D4 CLCN7 CLCA2	4.61e-08	258	109	11	CID000002376
Drug	gabapentin	GABRB1 GABRB3 GABRR1 GRINA GRM8 SLC5A11 CACNA2D4 SCN3A	1.57e-06	169	109	8	CID000003446
Drug	picrotoxin	GABRB1 GABRB3 GABRR1 GRINA GRM8 CACNA2D4 CLCN7 CLCA2	2.62e-06	181	109	8	CID000031304
Drug	pentylenetetrazol	GABRB1 GABRB3 GABRR1 GALR1 ACLY DUSP7 GRINA	3.09e-06	130	109	7	CID000005917
Drug	Quazepam	GABRB1 GABRB3 GABRR1	3.68e-06	7	109	3	DB01589
Drug	ketamine	GABRB1 GABRB3 GABRR1 CHRNA9 GRINA GRM8 OPRM1 SCN3A CRAMP1	4.83e-06	262	109	9	CID000003821
Drug	Adinazolam	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	DB00546
Drug	Fludiazepam	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	DB01567
Drug	Clotiazepam	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	DB01559
Drug	Cinolazepam	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	DB01594
Drug	Prazepam	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	DB01588
Drug	Estazolam	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	DB01215
Drug	Halazepam	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	DB00801
Drug	1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane	GABRB1 GABRB3 GABRR1	5.87e-06	8	109	3	ctd:C091518
Drug	tetradotoxin	GABRB1 GABRB3 GABRR1 GALR1 CHRNA9 GRINA GRM8 OPRM1 CACNA2D4 SCN3A TACR2	6.70e-06	428	109	11	CID000020382
Drug	Diazepam	GABRB1 GABRB3 GABRR1	8.78e-06	9	109	3	DB00829
Drug	Chlordiazepoxide	GABRB1 GABRB3 GABRR1	1.25e-05	10	109	3	DB00475
Drug	Clobazam	GABRB1 GABRB3 GABRR1	1.25e-05	10	109	3	DB00349
Drug	Bromazepam	GABRB1 GABRB3 GABRR1	1.25e-05	10	109	3	DB01558
Drug	Oxazepam	GABRB1 GABRB3 GABRR1	1.25e-05	10	109	3	DB00842
Drug	Midazolam	GABRB1 GABRB3 GABRR1	1.25e-05	10	109	3	DB00683
Drug	Flurazepam	GABRB1 GABRB3 GABRR1	1.25e-05	10	109	3	DB00690
Drug	Clonazepam	GABRB1 GABRB3 GABRR1	1.25e-05	10	109	3	DB01068
Drug	picrotoxinine	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2	1.51e-05	65	109	5	CID000004816
Drug	Alprazolam	GABRB1 GABRB3 GABRR1	1.71e-05	11	109	3	DB00404
Drug	Temazepam	GABRB1 GABRB3 GABRR1	1.71e-05	11	109	3	DB00231
Drug	Nitrazepam	GABRB1 GABRB3 GABRR1	1.71e-05	11	109	3	DB01595
Drug	Lorazepam	GABRB1 GABRB3 GABRR1	1.71e-05	11	109	3	DB00186
Drug	Triazolam	GABRB1 GABRB3 GABRR1	1.71e-05	11	109	3	DB00897
Drug	Clorazepate	GABRB1 GABRB3 GABRR1	1.71e-05	11	109	3	DB00628
Drug	gamma-aminobutyric acid	GABRB1 GABRB3 GABRR1 CHRNA9 SLC38A4 GRINA GRM8 OPRM1 CACNA2D4 CLCN7 CLCA2	1.74e-05	474	109	11	CID000000119
Drug	enflurane	GABRB1 GABRB3 GABRR1 GRINA CRAMP1	1.88e-05	68	109	5	CID000003226
Drug	riluzole	GABRB1 GABRB3 GABRR1 GRINA GRM8 CACNA2D4 SCN3A	2.09e-05	174	109	7	CID000005070
Drug	felbamate	GABRB1 GABRB3 GABRR1 GRINA GRM8	2.17e-05	70	109	5	CID000003331
Drug	ibotenic acid	PPRC1 GRINA GRM8 OPRM1 CLCN7 CLCA2	2.70e-05	122	109	6	CID000001233
Drug	acamprosate	GABRB1 GABRB3 GABRR1 GRINA GRM8	2.84e-05	74	109	5	CID000071158
Drug	heptachlor	GABRB1 GABRB3 PDS5B GABRR1 PSMB1 CRAMP1	3.70e-05	129	109	6	CID000003589
Drug	baclofen	GABRB1 GABRB3 GABRR1 GRINA GRM8 OPRM1 CACNA2D4	3.79e-05	191	109	7	CID000002284
Drug	Meclofenoxate hydrochloride [3685-84-5]; Up 200; 13.6uM; PC3; HT_HG-U133A	RIN3 TBC1D30 GRM8 SLC7A8 LTB4R EPN1 IL2RA	3.92e-05	192	109	7	4268_UP
Drug	sodium	GABRB1 GABRB3 GPR89B GABRR1 CHRNA9 PPRC1 SLC38A4 CHORDC1 SLC5A11 SLC7A8 CACNA2D4 SLC9A3 SCN3A EPN1 SLC9A6	4.38e-05	944	109	15	CID000000923
Drug	Fluocinonide [356-12-7]; Down 200; 8uM; PC3; HT_HG-U133A	RIN3 ATXN7L1 DUSP7 DUSP8 WDR25 GREB1L LPAR6	4.47e-05	196	109	7	4314_DN
Drug	atropine sulfate	GABRB1 GABRB3 GABRR1 CHRNA9 OPRM1 CLCN7 CLCA2 TACR2 MUSK	4.47e-05	347	109	9	CID000003661
Drug	Lactobionic acid [96-82-2]; Up 200; 11.2uM; PC3; HT_HG-U133A	TBC1D30 PSMB1 WDR25 SLC9A3 SMPDL3B CLCA2 LTB4R	4.62e-05	197	109	7	6605_UP
Drug	Suramin sodium salt; Down 200; 10uM; PC3; HT_HG-U133A	RIN3 DUSP8 LDAF1 SLC7A8 CLCN7 HPS1 EPN1	4.77e-05	198	109	7	7501_DN
Drug	Methacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; PC3; HT_HG-U133A	IFT140 RIN3 CHRNA9 SLC7A8 SMPDL3B HPS1 MYRF	4.77e-05	198	109	7	4062_DN
Drug	neostigmine	GABRB1 GABRB3 GABRR1 CHRNA9 MUSK	6.20e-05	87	109	5	CID000004456
Drug	benzodiazepine	GABRB1 GABRB3 GABRR1 CHRNA9 GRINA OPRM1	6.33e-05	142	109	6	CID000134664
Drug	dihydroxyaflavinine	GABRB1 GABRB3 GABRR1	6.91e-05	17	109	3	CID000156857
Drug	MK-801	GABRB1 GABRB3 GABRR1 CHRNA9 GRINA GRM8 OPRM1 CACNA2D4	9.06e-05	296	109	8	CID000001207
Drug	potassium	PDS5B GPR89B GALR1 CHRNA9 SLC38A4 GRINA GRM8 SLC5A11 SLC7A8 CACNA2D4 SLC9A3 CLCN7 CLCA2 SCN3A SLC9A6	9.17e-05	1008	109	15	CID000000813
Drug	pentobarbital	GABRB1 GABRB3 GABRR1 CHRNA9 GRINA OPRM1 SCN3A	1.03e-04	224	109	7	CID000004737
Drug	triazolam	GABRB1 GABRB3 GABRR1 MCHR2	1.31e-04	54	109	4	CID000005556
Drug	halothane	GABRB1 GABRB3 GABRR1 CHRNA9 MCHR2 CACNA2D4 LTB4R MUSK	1.36e-04	314	109	8	CID000003562
Drug	cyclothiazide	GABRB1 GABRB3 GABRR1 GRINA GRM8	1.38e-04	103	109	5	CID000002910
Drug	endrine	GABRB1 GABRB3 GABRR1 CLCN7 CLCA2	1.58e-04	106	109	5	CID000003048
Drug	methohexital	GABRB1 GABRB3 GABRR1	2.01e-04	24	109	3	CID000009034
Disease	Fulminant Hepatic Failure with Cerebral Edema	GABRB1 OPRM1 PRKDC	1.05e-05	13	100	3	C0751197
Disease	Hepatic Stupor	GABRB1 OPRM1 PRKDC	1.05e-05	13	100	3	C0751198
Disease	Hepatic Encephalopathy	GABRB1 OPRM1 PRKDC	1.05e-05	13	100	3	C0019151
Disease	Hepatic Coma	GABRB1 OPRM1 PRKDC	1.05e-05	13	100	3	C0019147
Disease	response to efavirenz, virologic response measurement	PIGN GRM8 OPRM1 SLC37A4	4.58e-05	58	100	4	EFO_0006904, EFO_0006906
Disease	lysophosphatidylcholine 18:0 measurement	UROC1 MYRF MUSK	7.26e-05	24	100	3	EFO_0010359
Disease	cholesteryl ester 14:0 measurement	SCN3A MYRF MUSK	1.04e-04	27	100	3	EFO_0010340
Disease	1-arachidonylglycerol (20:4) measurement	MYRF MUSK	1.69e-04	6	100	2	EFO_0800224
Disease	1-arachidonoylglycerophosphocholine measurement	MYRF MUSK	1.69e-04	6	100	2	EFO_0021076
Disease	1-linoleoylglycerophosphoethanolamine measurement	MYRF MUSK	1.69e-04	6	100	2	EFO_0021084
Disease	arachidonoylcholine measurement	MYRF MUSK	1.69e-04	6	100	2	EFO_0800478
Disease	lysophosphatidylcholine 18:3 measurement	MYRF MUSK	1.69e-04	6	100	2	EFO_0021454
Disease	1-docosapentaenoyl-GPC (22:5n3) measurement	MYRF MUSK	1.69e-04	6	100	2	EFO_0800298
Disease	Schizophrenia	GABRB1 GABRB3 GABRR1 MCHR2 BACE1 RB1CC1 GRM8 OPRM1 ADAMTS12 PLCL2 IL2RA	2.03e-04	883	100	11	C0036341
Disease	eicosapentaenoate (EPA; 20:5n3) measurement	MYRF MUSK	2.36e-04	7	100	2	EFO_0800616
Disease	arachidonate 20:4n6 measurement	MYRF MUSK	2.36e-04	7	100	2	EFO_0021063
Disease	1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) measurement	MYRF MUSK	2.36e-04	7	100	2	EFO_0800391
Disease	level of Phosphatidylcholine (O-18:2_20:4) in blood serum	MYRF MUSK	2.36e-04	7	100	2	OBA_2045135
Disease	1-eicosapentaenoyl-GPE (20:5) measurement	MYRF MUSK	2.36e-04	7	100	2	EFO_0800353
Disease	triacylglycerol 56:8 measurement	CACNA2D4 MYRF MUSK	2.49e-04	36	100	3	EFO_0010435
Disease	Unilateral agenesis of kidney	GREB1L FREM2	3.14e-04	8	100	2	C0266294
Disease	hydroxypalmitoyl sphingomyelin (d18:1/16:0(OH)) measurement	MYRF MUSK	3.14e-04	8	100	2	EFO_0800583
Disease	stearidonate 18:4n3 measurement	MYRF MUSK	3.14e-04	8	100	2	EFO_0021075
Disease	1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) measurement	MYRF MUSK	3.14e-04	8	100	2	EFO_0800392
Disease	level of Phosphatidylethanolamine (O-18:1_18:2) in blood serum	MYRF MUSK	3.14e-04	8	100	2	OBA_2045147
Disease	level of Phosphatidylethanolamine (O-18:2_20:4) in blood serum	MYRF MUSK	3.14e-04	8	100	2	OBA_2045151
Disease	Combined immunodeficiency	DOCK8 PRKDC IL2RA	3.67e-04	41	100	3	C0494261
Disease	autistic disorder (is_implicated_in)	GABRB1 GRM8 PTCHD1	3.94e-04	42	100	3	DOID:12849 (is_implicated_in)
Disease	1-arachidonoyl-GPE (20:4n6) measurement	MYRF MUSK	4.03e-04	9	100	2	EFO_0800248
Disease	level of Phosphatidylcholine (O-18:1_18:2) in blood serum	MYRF MUSK	4.03e-04	9	100	2	OBA_2045129
Disease	level of Phosphatidylcholine (O-18:1_20:3) in blood serum	MYRF MUSK	4.03e-04	9	100	2	OBA_2045130
Disease	1-stearoyl-2-arachidonoyl-GPC (18:0/20:4) measurement	MYRF MUSK	4.03e-04	9	100	2	EFO_0800271
Disease	tyrosine measurement	SLC38A4 DUSP7 PPP2R3A MYRF	4.40e-04	104	100	4	EFO_0005058
Disease	level of Phosphatidylcholine (O-18:2_16:0) in blood serum	MYRF MUSK	5.03e-04	10	100	2	OBA_2045132
Disease	cholesteryl ester 22:4 measurement	MYRF MUSK	5.03e-04	10	100	2	EFO_0021443
Disease	phosphatidylethanolamine ether measurement	MYRF MUSK	5.03e-04	10	100	2	EFO_0010229
Disease	phosphatidylcholine 32:0 measurement	GABRB3 MUSK	6.13e-04	11	100	2	EFO_0010372
Disease	level of Phosphatidylcholine (O-16:1_20:4) in blood serum	MYRF MUSK	6.13e-04	11	100	2	OBA_2045123
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRB1 GABRB3 GABRR1	6.21e-04	49	100	3	DOID:0060037 (implicated_via_orthology)
Disease	linoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement	MYRF MUSK	7.34e-04	12	100	2	EFO_0800500
Disease	level of Phosphatidylcholine (O-16:0_20:3) in blood serum	MYRF MUSK	7.34e-04	12	100	2	OBA_2045115
Disease	1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement	GREB1L MUSK	7.34e-04	12	100	2	EFO_0800453
Disease	cholesteryl ester 20:2 measurement	MYRF MUSK	7.34e-04	12	100	2	EFO_0021440
Disease	level of Phosphatidylinositol (18:1_18:1) in blood serum	MYRF MUSK	8.66e-04	13	100	2	OBA_2045159
Disease	level of Sphingomyelin (d34:2) in blood serum	MYRF MUSK	8.66e-04	13	100	2	OBA_2045174
Disease	phosphatidylcholine ether measurement	MYRF MUSK	8.66e-04	13	100	2	EFO_0010227
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	GREB1L MUSK	8.66e-04	13	100	2	OBA_2045082
Disease	level of Phosphatidylcholine (18:1_20:2) in blood serum	MYRF MUSK	1.01e-03	14	100	2	OBA_2045102
Disease	lysophosphatidylcholine 22:5 measurement	MYRF MUSK	1.01e-03	14	100	2	EFO_0021462
Disease	diacylglycerol 38:4 measurement	MYRF MUSK	1.01e-03	14	100	2	EFO_0020066
Disease	cis/trans-18:2 fatty acid measurement, trans fatty acid measurement	MYRF MUSK	1.16e-03	15	100	2	EFO_0006821, EFO_0006824
Disease	oleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement	MYRF MUSK	1.16e-03	15	100	2	EFO_0800508
Disease	level of Phosphatidylcholine (O-18:1_20:4) in blood serum	MYRF MUSK	1.16e-03	15	100	2	OBA_2045131
Disease	phosphatidate measurement	MYRF MUSK	1.16e-03	15	100	2	EFO_0020047
Disease	diacylglycerol 36:2 measurement	MYRF MUSK	1.32e-03	16	100	2	EFO_0010355
Disease	level of Phosphatidylcholine (18:0_20:3) in blood serum	MYRF MUSK	1.32e-03	16	100	2	OBA_2045093
Disease	basophil count, eosinophil count	RIN3 SLC9C1 PLCL2 PRKDC MUSK	1.40e-03	241	100	5	EFO_0004842, EFO_0005090
Disease	level of Phosphatidylinositol (18:0_18:1) in blood serum	MYRF MUSK	1.68e-03	18	100	2	OBA_2045155
Disease	diacylglycerol 36:3 measurement	MYRF MUSK	1.68e-03	18	100	2	EFO_0020062
Disease	level of Phosphatidylethanolamine (18:0_20:4) in blood serum	MYRF MUSK	1.87e-03	19	100	2	OBA_2045140
Disease	diacylglycerol 38:5 measurement	MYRF MUSK	1.87e-03	19	100	2	EFO_0020067
Disease	diacylglycerol 38:3 measurement	MYRF MUSK	1.87e-03	19	100	2	EFO_0020065
Disease	Alcoholic Intoxication, Chronic	GABRB1 GABRB3 GABRR1 GRM8 OPRM1	2.22e-03	268	100	5	C0001973
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	MYRF MUSK	2.29e-03	21	100	2	OBA_2045104
Disease	level of Phosphatidylcholine (16:0_20:4) in blood serum	MYRF MUSK	2.29e-03	21	100	2	OBA_2045076
Disease	level of Phosphatidylcholine (16:1_18:2) in blood serum	MYRF MUSK	2.29e-03	21	100	2	OBA_2045083
Disease	Lung diseases	DOCK8 HPS1 PRKDC	2.39e-03	78	100	3	C0024115
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	CHRNA9 GRM8	2.51e-03	22	100	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	level of Phosphatidylinositol (18:0_20:4) in blood serum	MYRF MUSK	2.75e-03	23	100	2	OBA_2045158
Disease	phosphatidylserines measurement	MYRF MUSK	2.75e-03	23	100	2	EFO_0020049
Disease	gamma-linolenic acid measurement	MYRF MUSK	2.99e-03	24	100	2	EFO_0007762
Disease	alpha-linolenic acid measurement	MYRF MUSK	3.24e-03	25	100	2	EFO_0007759
Disease	diacylglycerol 34:2 measurement	CACNA2D4 MUSK	3.24e-03	25	100	2	EFO_0010353

Protein segments in the cluster

Peptide	Gene	Start	Entry
DESTLMTIAYVMAAI	BACE1	451	P56817
MTDRILYIVSNMSSV	DPEP2NB	1	A0A0U1RQF7
SSALNTVEMMPNSIY	ARAP3	146	Q8WWN8
SVLSTYTVNDLSMMK	CARNMT1	381	Q8N4J0
MTMQTSTLDVTPVIY	ADGRG4	1601	Q8IZF6
SRSATIAIAYIMKTM	DUSP8	251	Q13202
IFMKYDLSSLMVTVT	ERGIC2	291	Q96RQ1
RTTVSNVKMDILSYM	GPX3	201	P22352
TASTALTIMVMNIHF	CHRNA9	311	Q9UGM1
YIMTSAMLSNAAFVT	ATXN7L1	556	Q9ULK2
NVESYILTIMNMVTG	ADAMTS12	266	P58397
ILTYIHTMNVMITNT	CPXCR1	256	Q8N123
VAMNIIMSKSTTYSL	PDS5B	1071	Q9NTI5
TTLASTLMEQYMKAT	RASA1	791	P20936
NMYSSILTMTCISVE	P2RY8	106	Q86VZ1
TCISTLLMLVTSDMY	SLC7A8	371	Q9UHI5
STYNVSISTRMVMIE	PAPOLB	326	Q9NRJ5
TFMVSESLLLASMAY	OR8U8	106	P0C7N1
SPEMMVESLYSSVIN	RB1CC1	756	Q8TDY2
QDMVASVMYTAITPL	OR1B1	276	Q8NGR6
DTTMYEMQALASTLL	OR10A7	191	Q8NGE5
SMITAITIMALYSIV	OPRM1	66	P35372
LSVLTASLSYMVGMI	GRINA	231	Q7Z429
TISSMYQTKAVIIAM	TMBIM1	181	Q969X1
LTYNVVAFSEIMSMV	EPN2	46	O95208
MSSLVSSYLQTQEMV	FYCO1	201	Q9BQS8
TLSLKDMVTYFMNLS	SMPDL3B	331	Q92485
AIVYIEEMSSMADVT	FREM2	2356	Q5SZK8
LTVIMMEATSNVTYG	CLCN7	566	P51798
VMMKYLDNLSTSQLS	NEK10	786	Q6ZWH5
MMIASYVVVSSLISC	LDAF1	116	Q96B96
SSMETILPIMNQYTE	RHOT1	126	Q8IXI2
SQLSLMDMAYISVTV	OR2T4	96	Q8NH00
FISQLSLMDMAYISV	OR2T5	66	Q6IEZ7
VVAEMASYLETMNIT	PGM2L1	456	Q6PCE3
AEYTNIIMMNTLTTT	MT-ND1	226	P03886
IIMMNTLTTTIFLGT	MT-ND1	231	P03886
SIDMVSEVNMDYTLT	GABRB1	71	P18505
SIDMVSEVNMDYTLT	GABRB3	71	P28472
ETTTYMINLAMSDLL	LPAR6	51	P43657
ISVSYTMILQAVMSL	OR52N2	216	Q8NGI0
DKAVAVFYTMITSML	OR4C13	266	Q8NGP0
QSFSLTMSIEMPYVI	PARP4	781	Q9UKK3
LTTTKRSYEDQLSMM	PPP1R21	731	Q6ZMI0
MYIQTTTLTVSMSLS	GRM8	811	O00222
LIQQYSEALMALTTM	GREB1L	911	Q9C091
ISSSETVYMNVMTRL	PPP2R3A	271	Q06190
MYASVLLITAMSLDR	LTB4R	101	Q15722
FISQLSLMDMAYISV	OR2T29	66	Q8NH02
SAIMTVMSVDRYFAL	MCHR2	121	Q969V1
TVSMLVSIFTLAAMS	GALR1	116	P47211
MTVSMYLFRVTVTSD	SLC37A4	311	O43826
VLYSLRVTVTAMCNM	GABRR1	186	P24046
MTDSVIYSMLELPTA	KLRG1	1	Q96E93
TILAYSEEDTAMQMT	DOCK8	1576	Q8NF50
AYSMMTTQVLSLSSL	C3P1	206	Q6ZMU1
MSFLIDSSIMITSQI	GPR89A	1	B7ZAQ6
MSFLIDSSIMITSQI	GPR89B	1	P0CG08
TQLLSMGVFSQVTMY	CACNA2D4	921	Q7Z3S7
QTSESLTLAEVYLMM	CRAMP1	681	Q96RY5
TQATLLYTMADKIIM	CTR9	111	Q6PD62
SRSVTVTVAYLMQKM	DUSP7	336	Q16829
MAATMETSIFTTEYQ	IL2RA	226	P01589
VLMCYAIMVTASVSN	MBOAT1	91	Q6ZNC8
LTYNVVAFSEIMSMI	EPN1	46	Q9Y6I3
LAATTSMAYAKLMLT	FANCE	481	Q9HB96
IICMVTMETSNAYVA	FLRT1	476	Q9NZU1
LMGLYVDMNATTVTV	C1orf127	56	Q8N9H9
ISSMTMLEKLSDTYT	HPS1	56	Q92902
EMDPVTQLYTMTSTL	ALCAM	191	Q13740
VVSADSTIQMLFYME	IFT140	226	Q96RY7
TTRLIVNLSQTYMAM	MFSD12	286	Q6NUT3
AAISMVVAMAVYTSE	NKG7	101	Q16617
LGTMQSYMDASLISL	PPRC1	91	Q5VV67
MTTGAIAAMLSTILY	PSMB1	111	P20618
AMFVSIYSMTAIAAD	TACR2	116	P21452
METLITAMEQLYTLG	DHX8	951	Q14562
NKSLVSMSATMAEIY	MAP1LC3C	91	Q9BXW4
TMMTQLKSYLLQSTE	RIN3	646	Q8TB24
TFMISESLLLASMAY	OR8U1	106	Q8NH10
TVLMYILRMANETDS	RNF139	251	Q8WU17
AMYLSDTTVTMLANL	TAS2R45	171	P59539
KSDIYSFSMIMQEIL	TEX14	436	Q8IWB6
ATYARQMMFSTTLLI	SLC9A6	471	Q92581
LMTSVISLITFTSIM	SLC9C1	176	Q4G0N8
SMTIMVLLCSYSVGQ	SLC22A24	231	Q8N4F4
SMLSFSLTTAMYLVT	PTCHD1	371	Q96NR3
TVMAGLTTALSMIVY	SLC35G2	261	Q8TBE7
VTTYDMMIQSLKALI	PLCL2	1001	Q9UPR0
RYTMKMLASSAETII	SLC9A3	336	P48764
GMLMLSATQVYTILT	RNF13	6	O43567
MVAALMSSLTSIFNS	SLC5A11	381	Q8WWX8
LSSYQISMEMLEDSS	SCN3A	686	Q9NY46
VSITMQNIGAMSSYL	SLC38A4	156	Q969I6
TVSNISITGMLVMYL	SLC38A4	366	Q969I6
TSTLLALIMMPVNSY	SLC10A5	241	Q5PT55
STMETMNYAQIRTIA	ACLY	581	P53396
ATASIMFMQSLSSVV	CLCA2	236	Q9UQC9
SYVTMTATKIEITMR	CHORDC1	291	Q9UHD1
ITEYFSVLVNMDMSL	CNOT11	391	Q9UKZ1
LMGTISSILSMYQAA	PEX11G	216	Q96HA9
TMFYLSKMTEEQTLV	UROC1	141	Q96N76
LTAKMETQSMYVSEL	TRAF6	316	Q9Y4K3
LLQSHELMQTVYSMA	TBC1D30	501	Q9Y2I9
SISHYVIVMSMTIFL	PIGN	891	O95427
YVALNMTSASSFQML	SLC35F6	106	Q8N357
LTVTSSDEMMKSYVA	PRKDC	871	P78527
QVISLLTMGINSYVM	SLC9C2	411	Q5TAH2
AIEVMTVASYLQMSE	ZBTB10	436	Q96DT7
MTARTLSLMASLVAY	WDR25	1	Q64LD2
VYNMVMSDVTISCTS	TOPBP1	101	Q92547
MMENYSSLVSLGLSI	ZNF850	36	A8MQ14
TYSMTVIISIMSSFA	MUSK	491	O15146
DDLLTSYISQMLTAM	MYO7A	2191	Q13402
MAFSVVSMSTLYVLS	MYRF	776	Q9Y2G1