Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncysteine-type deubiquitinase activity

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.16e-1911411517GO:0004843
GeneOntologyMolecularFunctiondeubiquitinase activity

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

5.14e-1912411517GO:0101005
GeneOntologyMolecularFunctionubiquitin-like protein peptidase activity

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

2.95e-1813711517GO:0019783
GeneOntologyMolecularFunctioncysteine-type peptidase activity

USP17L7 USP17L21 CTSF USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

4.64e-1719211518GO:0008234
GeneOntologyMolecularFunctionpeptidase activity

USP17L7 USP17L21 CTSF USP17L4 USP17L2 USP17L1 PITRM1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

6.10e-0965411519GO:0008233
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

HIVEP2 VEZF1 ZNF391 SOX30 ZNF195 ZNF880 CHD7 ZNF362 EBF1 SIX4 ZNF251 CASZ1 ZNF677 ZNF263 DMRT2 ZNF256 ZNF667 ZNF471 NFAT5 ZNF281 PRDM16 SMAD5 ZNF574 ZNF124

2.39e-06145911524GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

HIVEP2 SOX30 ZNF195 ZNF880 CHD7 ZNF362 EBF1 SIX4 ZNF251 ZNF677 ZNF263 DMRT2 ZNF256 ZNF667 ZNF471 NFAT5 ZNF281 PRDM16 SMAD5 ZNF574

2.65e-05124411520GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

HIVEP2 SOX30 ZNF195 ZNF880 CHD7 ZNF362 EBF1 SIX4 ZNF251 ZNF677 ZNF263 DMRT2 ZNF256 ZNF667 ZNF471 NFAT5 ZNF281 PRDM16 SMAD5 ZNF574

3.59e-05127111520GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

HIVEP2 VEZF1 ZNF391 SOX30 ZNF195 ZNF880 EBF1 SIX4 ZNF251 CASZ1 ZNF677 ZNF263 DMRT2 ZNF256 ZNF471 NFAT5 ZNF281 PRDM16 SMAD5 ZNF574 ZNF124

5.09e-05141211521GO:0000981
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

HIVEP2 VEZF1 SOX30 EBF1 SIX4 CASZ1 DMRT2 NFAT5 PRDM16 ZNF574

1.49e-0356011510GO:0001228
GeneOntologyMolecularFunctionSMAD binding

SMURF1 ZMIZ1 PRDM16 SMAD5

1.54e-03861154GO:0046332
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

HIVEP2 VEZF1 SOX30 EBF1 SIX4 CASZ1 DMRT2 NFAT5 PRDM16 ZNF574

1.61e-0356611510GO:0001216
GeneOntologyBiologicalProcessprotein deubiquitination

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

2.97e-1912511417GO:0016579
GeneOntologyBiologicalProcessprotein modification by small protein removal

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

3.53e-1814411417GO:0070646
GeneOntologyBiologicalProcessprotein modification by small protein conjugation or removal

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 UBR4 USP17L24 SMURF1 USP17L5 AMBRA1 MARCHF7 USP17L10 ZMIZ1 USP17L18 USP31 USP17L17 ANAPC1 TRIM8 USP17L3 USP17L15 USP17L8 USP17L13

1.10e-09100911424GO:0070647
GeneOntologyBiologicalProcesspost-translational protein modification

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 UBR4 USP17L24 SMURF1 USP17L5 AMBRA1 MARCHF7 USP17L10 ZMIZ1 USP17L18 USP31 USP17L17 ANAPC1 TRIM8 USP17L3 USP17L15 USP17L8 USP17L13

3.76e-09107411424GO:0043687
HumanPhenoNarrow mouth

ASXL1 HIVEP2 CHD7 ZMIZ1 JMJD1C CASZ1 RTL1 PRDM16

1.34e-05234268HP:0000160
HumanPhenoAbnormality of mouth size

ASXL1 HIVEP2 CENPF CHD7 ZMIZ1 JMJD1C CASZ1 RTL1 KCNN3 PRDM16

2.30e-054252610HP:0011337
MousePhenoincreased thymus weight

USP17L2 PPARGC1A USP17L15 USP17L13

7.49e-0624754MP:0004955
MousePhenoincreased trophectoderm apoptosis

USP17L2 USP17L15 USP17L13

8.15e-068753MP:0012119
MousePhenoabnormal vitelline vascular remodeling

UBR4 ZMIZ1 PTPRJ TJP1 SMAD5

1.83e-0561755MP:0004076
MousePhenoabnormal artery development

VEZF1 CHD7 ZMIZ1 PTPRJ NGFR SMAD5

7.79e-05133756MP:0003410
MousePhenoabnormal extraembryonic tissue physiology

USP17L2 UBR4 ZMIZ1 PTPRJ RTL1 TJP1 USP17L15 SMAD5 USP17L13

9.16e-05345759MP:0004264
MousePhenodilated dorsal aorta

ZMIZ1 NGFR SMAD5

1.14e-0418753MP:0004068
DomainHABP4_PAI-RBP1

USP17L7 USP17L21 USP17L2 USP17L20 USP17L11 USP17L24 USP17L5 USP17L18 USP17L17 USP17L3 USP17L13

9.28e-221611211PF04774
DomainHABP4_PAIRBP1-bd

USP17L7 USP17L21 USP17L2 USP17L20 USP17L11 USP17L24 USP17L5 USP17L18 USP17L17 USP17L3 USP17L13

9.28e-221611211IPR006861
DomainUCH

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L8 USP17L13

2.24e-217111216PF00443
DomainUSP_2

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L8 USP17L13

2.24e-217111216PS00973
DomainUSP_3

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L8 USP17L13

2.87e-217211216PS50235
DomainUSP_dom

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L8 USP17L13

2.87e-217211216IPR028889
DomainPeptidase_C19_UCH

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L8 USP17L13

2.87e-217211216IPR001394
DomainUSP_CS

USP17L7 USP17L21 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L8 USP17L13

3.68e-206611215IPR018200
DomainUSP_1

USP17L7 USP17L21 USP17L4 USP17L2 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP31 USP17L17 USP17L3 USP17L8 USP17L13

9.70e-207011215PS00972
Domainzf-C2H2

BNC2 HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 CASZ1 ZNF677 ZNF106 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

2.85e-0869311219PF00096
DomainZINC_FINGER_C2H2_2

BNC2 HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 CASZ1 ZNF677 ZNF106 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

1.64e-0777511219PS50157
DomainZINC_FINGER_C2H2_1

BNC2 HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 CASZ1 ZNF677 ZNF106 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

1.71e-0777711219PS00028
DomainZnf_C2H2-like

BNC2 HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 CASZ1 ZNF677 ZNF106 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

2.48e-0779611219IPR015880
DomainZnf_C2H2

BNC2 HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 CASZ1 ZNF677 ZNF106 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

2.94e-0780511219IPR007087
DomainZnF_C2H2

BNC2 HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 CASZ1 ZNF677 ZNF106 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

3.12e-0780811219SM00355
Domain-

HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 ZNF677 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

2.89e-06679112163.30.160.60
DomainZnf_C2H2/integrase_DNA-bd

HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 ZNF677 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

3.82e-0669411216IPR013087
Domainzf-C2H2_6

ZNF391 ZNF195 ZNF880 ZNF251 ZNF677 ZNF256 ZNF667 PRDM16 ZNF574

1.15e-043141129PF13912
DomainKRAB

ZNF195 ZNF880 ZNF251 ZNF677 ZNF263 ZNF256 ZNF667 ZNF471 ZNF124

3.06e-043581129PS50805
DomainKRAB

ZNF195 ZNF880 ZNF251 ZNF677 ZNF263 ZNF256 ZNF667 ZNF471 ZNF124

3.06e-043581129PF01352
DomainKRAB

ZNF195 ZNF880 ZNF251 ZNF677 ZNF263 ZNF256 ZNF667 ZNF471 ZNF124

3.82e-043691129SM00349
DomainKRAB

ZNF195 ZNF880 ZNF251 ZNF677 ZNF263 ZNF256 ZNF667 ZNF471 ZNF124

3.90e-043701129IPR001909
DomainBRK

CHD9 CHD7

5.26e-0461122SM00592
DomainBRK_domain

CHD9 CHD7

5.26e-0461122IPR006576
DomainBRK

CHD9 CHD7

5.26e-0461122PF07533
PathwayREACTOME_RAS_PROCESSING

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

4.27e-24457415MM15671
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

4.96e-141917415MM15289
PathwayREACTOME_DEUBIQUITINATION

USP17L7 USP17L21 ASXL1 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

3.29e-132627416MM15286
PathwayREACTOME_UB_SPECIFIC_PROCESSING_PROTEASES

USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

4.25e-132217415M27578
PathwayREACTOME_DEUBIQUITINATION

USP17L21 ASXL1 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

2.50e-122997416M27574
PathwayREACTOME_MAPK_FAMILY_SIGNALING_CASCADES

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 SPTBN5 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

6.37e-123187416MM15278
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L21 ASXL1 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 LAMB2 USP17L5 USP17L10 ITIH2 USP17L18 SPTBN5 PPARGC1A USP17L17 SEC16A USP17L3 USP17L15 USP17L8 USP17L13

1.45e-0514757421M19806
PathwayREACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION

USP17L7 USP17L21 ASXL1 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 ITIH2 USP17L18 SPTBN5 USP17L17 SEC16A USP17L3 USP17L15 USP17L8 USP17L13

7.22e-0513897419MM15307
PathwayREACTOME_SARS_COV_2_TARGETS_PDZ_PROTEINS_IN_CELL_CELL_JUNCTION

TJP1 PATJ

2.69e-045742M45010
PathwayWP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE

PPARGC1A PRDM16 SMAD5

2.94e-0425743M39665
PathwayWP_FTO_OBESITY_VARIANT_MECHANISM

PPARGC1A PRDM16

7.46e-048742M39356
Pubmed

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.27e-3321115158622927
Pubmed

DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.27e-33211151514583620
Pubmed

DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.27e-33211151511468161
Pubmed

The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.27e-3321115158756639
Pubmed

Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.27e-33211151512447969
Pubmed

DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.27e-33211151518980247
Pubmed

JAK2 is required for induction of the murine DUB-1 gene.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

3.99e-3322115159154835
Pubmed

DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

3.04e-3224115158995226
Pubmed

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

7.59e-32251151521115691
Pubmed

Cdc25A and Dub3 in a high-stakes balancing act.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

7.65e-32331151620228807
Pubmed

The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151620403174
Pubmed

Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151617109758
Pubmed

The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151620388806
Pubmed

DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151614699124
Pubmed

Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151620715989
Pubmed

Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-3134115169806828
Pubmed

The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151620368735
Pubmed

The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151615780755
Pubmed

USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151619188362
Pubmed

Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151611941478
Pubmed

The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151610936051
Pubmed

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.44e-31341151621448158
Pubmed

Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.79e-31261151535816173
Pubmed

Cytokine-regulated protein degradation by the ubiquitination system.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

2.65e-31351151616611142
Pubmed

Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

2.65e-31351151621239494
Pubmed

The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

4.75e-31361151620147298
Pubmed

Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

8.35e-31371151620228808
Pubmed

Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.78e-30291151532527007
Pubmed

DUX is a non-essential synchronizer of zygotic genome activation.

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

4.89e-26501151531806660
Pubmed

High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8

4.27e-1610115724207026
Pubmed

Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8

2.80e-1512115724695638
Pubmed

ES cell neural differentiation reveals a substantial number of novel ESTs.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8

1.21e-1414115711793228
Pubmed

CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8

1.75e-1319115728067227
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

USP17L7 USP17L21 SERPINA3 USP17L4 MYOT USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

9.41e-116741151737196079
Pubmed

Human and mouse proteases: a comparative genomic approach.

USP17L7 USP17L4 USP17L2 USP17L1 USP31 USP17L3 USP17L15 USP17L8

2.94e-1081115812838346
Pubmed

Human transcription factor protein interaction networks.

ASXL1 PITRM1 VEZF1 UBR4 MRPL10 CHD7 ZMIZ1 SIX4 ANKHD1 JMJD1C KIAA1671 SEC16A UNK GIGYF2 EIF3A QSER1 CABIN1 ZNF471 ZNF281 PRDM16 SMAD5

8.77e-0914291152135140242
Pubmed

Interaction network of human early embryonic transcription factors.

HIVEP2 CHD7 ZMIZ1 SIX4 KIAA1671 ZNF263 TNRC18 SEC16A QSER1 ZNF281 PRDM16

2.64e-083511151138297188
Pubmed

Embryonic demise caused by targeted disruption of a cysteine protease Dub-2.

USP17L2 USP17L15 USP17L13

1.41e-074115322984479
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

TANC2 RALGAPB FAM83B KIAA1671 ANAPC1 TJP1 SEC16A UNK GIGYF2 PATJ XPR1

2.94e-074461151124255178
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

LRWD1 VEZF1 RALGAPB LAMB2 CHD7 SIX4 ANKHD1 CASZ1 KIAA2013 FAM83B KIAA1671 ANAPC1 UNK EIF3A PATJ ZNF281 ZNF574 XPR1 DUSP11

4.68e-0714971151931527615
Pubmed

DNA sequence and analysis of human chromosome 8.

USP17L7 USP17L4 USP17L1 USP17L3 USP17L8

5.53e-0748115516421571
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TANC2 LRWD1 HIVEP2 UBR4 LAMB2 AMBRA1 ANKHD1 ADGRA2 CASZ1 KIAA2013 PCNX2 ZNF263 TNRC18 SEC16A CABIN1 PRDM16

7.61e-0711051151635748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MIER2 TANC2 ARHGEF28 JMJD1C CASZ1 KIAA2013 TRIM66 TNRC18 ATRNL1 EIF3A PRDM16

7.86e-074931151115368895
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TANC2 HIVEP2 ARHGEF28 CEP85L RALGAPB PAK6 FAM83B KIAA1671 USP31 ZNF106 TJP1 SEC16A GIGYF2 PATJ

1.03e-068611151436931259
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CENPF UBR4 CHD7 ZMIZ1 ANKHD1 JMJD1C KIAA1671 ANAPC1 SEC16A GIGYF2

1.37e-064181151034709266
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

ANKHD1 PAIP1 JMJD1C ZNF106 ANAPC1 GIGYF2 QSER1 ZNF281

1.53e-06242115834011540
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

CENPF ZNF362 JMJD1C ZNF106 QSER1 ZNF281

2.53e-06116115630804394
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

PITRM1 CENPF CHD7 SEC16A ZNF281 SNX22 DUSP11

4.39e-06197115720811636
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

MIER2 LRWD1 VEZF1 CHD9 CHD7 ZNF362 JMJD1C CASZ1 QSER1 CABIN1 ZNF281

5.87e-066081151136089195
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

VEZF1 CHD7 SIX4 JMJD1C CASZ1 TNRC18 SEC16A MYO15A PRDM16

7.43e-06398115935016035
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

CHD7 ZNF362 SIX4 JMJD1C ZNF281

8.56e-0683115528794006
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ASXL1 RALGAPB CHD7 ADGRA2 SEC16A GIGYF2 PRDM16

1.05e-05225115712168954
Pubmed

The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons.

ASIC3 PATJ

1.08e-052115211872753
Pubmed

Poly(A)-binding protein-interacting protein 1 binds to eukaryotic translation initiation factor 3 to stimulate translation.

PAIP1 EIF3A

1.08e-052115218725400
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

CHD9 TRIM66 SEC16A CABIN1 PCDHGA8

2.57e-0510411559205841
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

KCNB2 JMJD1C FAM83B KIAA1671 TJP1 SEC16A GIGYF2

2.85e-05263115734702444
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

CHD7 ZNF362 JMJD1C CASZ1 TNRC18 QSER1 ZNF281

3.22e-05268115733640491
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

HIVEP2 RALGAPB SMURF1 CHD9 ZNF362 ZMIZ1 JMJD1C CASZ1 PCNX2 KIAA1671 TNRC18 PTPRJ TJP1 QSER1 PATJ NFAT5

3.23e-0514891151628611215
Pubmed

Uncoupling protein-1 and related messenger ribonucleic acids in human epicardial and other adipose tissues: epicardial fat functioning as brown fat.

PPARGC1A PRDM16

3.24e-053115219567523
Pubmed

Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure.

PPARGC1A PRDM16

3.24e-053115228824327
Pubmed

Transcriptional control of brown fat determination by PRDM16.

PPARGC1A PRDM16

3.24e-053115217618855
Pubmed

Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins.

SMURF1 SMAD5

3.24e-053115214711801
Pubmed

Molecular Interaction Between Smurfl WW2 Domain and PPXY Motifs of Smadl, Smad5, and Smad6-Modeling and Analysis.

SMURF1 SMAD5

3.24e-053115222670624
Pubmed

Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

PPARGC1A PRDM16

3.24e-053115222033933
Pubmed

Imprinted gene dosage is critical for the transition to independent life.

PPARGC1A RTL1 PRDM16

3.85e-0520115322326222
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

UBR4 CHD9 CHD7 TNRC18 ANAPC1 SEC16A QSER1

4.44e-05282115723667531
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

USP17L21 USP17L20 USP17L11 USP17L18 USP17L17

4.90e-05119115528625976
Pubmed

Molecular interaction between Smurf1 WW2 domain and PPXY motifs of Smad1, Smad5, and Smad6--modeling and analysis.

SMURF1 SMAD5

6.48e-054115217676934
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 AMBRA1 CHD9 ZNF362 ANKHD1 KIAA1671 TRIM66 ANAPC1 CAPRIN2 SEC16A ZNF281 PRDM16 ZNF574

8.46e-0511161151331753913
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ANKHD1 JMJD1C KIAA1671 ANAPC1 TJP1 SEC16A GIGYF2 QSER1 PATJ

9.11e-05549115938280479
Pubmed

EZH2 Mediates epigenetic silencing of neuroblastoma suppressor genes CASZ1, CLU, RUNX3, and NGFR.

CASZ1 NGFR

1.08e-045115222068036
Pubmed

Density-enhanced phosphatase 1 regulates phosphorylation of tight junction proteins and enhances barrier function of epithelial cells.

PTPRJ TJP1

1.08e-045115219332538
Pubmed

Paip1, an effective stimulator of translation initiation, is targeted by WWP2 for ubiquitination and degradation.

PAIP1 EIF3A

1.08e-045115225266661
Pubmed

The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development.

SMURF1 SMAD5

1.08e-045115229934521
Pubmed

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

PPARGC1A PRDM16

1.08e-045115218483224
Pubmed

Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1.

SMURF1 SMAD5

1.08e-045115218641638
Pubmed

Hgs physically interacts with Smad5 and attenuates BMP signaling.

SMURF1 SMAD5

1.08e-045115216516194
Pubmed

EBF2 determines and maintains brown adipocyte identity.

EBF1 PPARGC1A PRDM16

1.21e-0429115323499423
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

BNC2 CHD7 SEC16A QSER1 ZNF281

1.29e-04146115523892456
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

UBR4 ANKHD1 CASZ1 PCNX2 EXOC1 EIF3A

1.30e-04233115637704626
Pubmed

A germline-specific class of small RNAs binds mammalian Piwi proteins.

B3GALNT1 CTSF LRWD1 LAMB2 KIAA1671 TRIM66 SEC16A ZFYVE19

1.31e-04450115816751776
Pubmed

Mouse embryo geometry drives formation of robust signaling gradients through receptor localization.

TJP1 SMAD5

1.61e-046115231586065
Pubmed

Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.

TJP1 PATJ

1.61e-046115217397395
Pubmed

Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradation.

SMURF1 SMAD5

1.61e-046115224828823
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

CHD7 PAIP1 JMJD1C ZNF106 ANAPC1 TJP1 SEC16A UNK QSER1 PATJ

1.66e-047331151034672954
Pubmed

Identification of mZnf8, a mouse Krüppel-like transcriptional repressor, as a novel nuclear interaction partner of Smad1.

SMURF1 SMAD5

2.25e-047115212370310
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TANC2 MXRA5 UBR4 MRPL10 CHD7 ZNF251 CASZ1 TRIM8 ZNF281

2.79e-04638115931182584
Pubmed

Asymmetric distribution of CRUMBS polarity complex proteins from compacted 8-cell to blastocyst stage during mouse preimplantation development.

TJP1 PATJ

3.00e-048115229155075
Pubmed

Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths.

LAMB2 TJP1

3.00e-048115210482238
Pubmed

Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF.

TJP1 PATJ

3.00e-048115222006950
Pubmed

Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.

SMURF1 SMAD5

3.00e-048115220484049
Pubmed

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

SMURF1 SMAD5

3.00e-048115211278251
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ARHGEF28 RALGAPB AMBRA1 ANKHD1 JMJD1C GIGYF2 QSER1 PATJ ZNF574

3.19e-04650115938777146
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TANC2 CENPF UBR4 CHD7 ZNF263 ANAPC1 TJP1 SEC16A GIGYF2 QSER1 CABIN1

3.60e-049631151128671696
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

MIER2 BNC2 VEZF1 ZNF195 EBF1 SIX4 ZNF263 UNK NFAT5 PRDM16

3.60e-048081151020412781
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

JMJD1C TJP1 SEC16A GIGYF2 ZNF281

3.76e-04184115532908313
Pubmed

Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice.

NGFR MYO15A

3.84e-049115220063299
Pubmed

The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration.

LAMB2 NGFR

3.84e-049115219295126
Pubmed

Prdm16 is required for normal palatogenesis in mice.

PRDM16 SMAD5

3.84e-049115220007998
Pubmed

Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia.

SMURF1 SMAD5

3.84e-049115215123739
InteractionPHF21A interactions

CENPF UBR4 CHD7 ZMIZ1 ANKHD1 JMJD1C KIAA1671 ANAPC1 SEC16A GIGYF2 EXOC1

2.81e-0634311011int:PHF21A
InteractionEGR2 interactions

HIVEP2 CHD7 SIX4 TNRC18 SEC16A QSER1 ZNF281 PRDM16

4.48e-061711108int:EGR2
InteractionSOX7 interactions

CHD7 JMJD1C CASZ1 TNRC18 PRDM16 SMAD5

5.76e-06821106int:SOX7
InteractionFBXO38 interactions

CENPF SOX30 ZNF362 JMJD1C ZNF106 QSER1 ZNF281

1.48e-051451107int:FBXO38
Cytoband4p16.1

USP17L21 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L15 USP17L13

8.12e-1579115104p16.1
CytobandEnsembl 112 genes in cytogenetic band chr4p16

USP17L21 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L15 USP17L13

2.73e-1022211510chr4p16
Cytoband8p23.1

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L8

2.69e-0615411568p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

USP17L7 USP17L4 USP17L2 USP17L1 USP17L3 USP17L8

2.91e-052341156chr8p23
Cytoband5q31

MYOT PCDHGA9 PCDHGA8 SMAD5

2.08e-0411511545q31
CytobandEnsembl 112 genes in cytogenetic band chr15q15

PAK6 SPTBN5 ZNF106 ZFYVE19

5.29e-041471154chr15q15
CytobandEnsembl 112 genes in cytogenetic band chr5q31

MYOT PCDHGA9 ANKHD1 PCDHGA8 SMAD5

9.56e-042981155chr5q31
Cytoband19q13.43

ZNF256 ZNF667 ZNF471

1.39e-0387115319q13.43
Cytoband10q26

ATRNL1 EIF3A

1.52e-0323115210q26
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

BNC2 HIVEP2 VEZF1 ZNF391 ZNF195 ZNF880 ZNF362 ZNF251 CASZ1 ZNF677 ZNF106 ZNF263 ZNF256 ZNF667 ZNF471 ZNF281 PRDM16 ZNF574 ZNF124

3.08e-11718721928
CoexpressionMADAN_DPPA4_TARGETS

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.85e-208611215MM1312
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

1.22e-1811211215MM1095
CoexpressionGERY_CEBP_TARGETS

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 CAPRIN2 USP17L3 USP17L15 USP17L8 USP17L13

9.94e-1816011216MM1155
CoexpressionGRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 USP17L17 ANGPT4 USP17L3 ZNF281 USP17L15 USP17L8 USP17L13

2.32e-0964711217MM981
CoexpressionBRUINS_UVC_RESPONSE_LATE

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 CEP85L USP17L20 USP17L11 SMURF1 USP17L5 USP17L10 ADGRA2 PAIP1 USP17L18 USP17L17 USP17L3 UNK DKKL1 USP17L15 USP17L8 USP17L13

3.27e-08119811221MM1062
CoexpressionMARSON_BOUND_BY_FOXP3_STIMULATED

USP17L7 USP17L21 USP17L4 THEMIS USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 USP17L18 PTPRJ USP17L17 USP17L3 NFAT5 ZNF281 USP17L15 USP17L8 USP17L13

1.37e-07107211219MM1031
CoexpressionGRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP

USP17L7 USP17L21 USP17L4 LRWD1 USP17L2 USP17L1 USP17L20 USP17L11 USP17L5 USP17L10 KIAA2013 USP17L18 USP17L17 ANGPT4 CAPRIN2 USP17L3 ZNF281 USP17L15 USP17L8 USP17L13

2.32e-07122611220MM979
CoexpressionLAKE_ADULT_KIDNEY_C17_COLLECTING_SYSTEM_PCS_STRESSED_DISSOC_SUBSET

TANC2 HIVEP2 JMJD1C PPARGC1A PIK3C2G TJP1 NFAT5

7.92e-052401127M39236
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 FAM83B PPARGC1A DMRT2 NFAT5 PRDM16

4.14e-071881097e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

TANC2 CENPF ZNF106 TJP1 SEC16A TRIM8 SMAD5

5.86e-07198109776d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellNS-moderate-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BNC2 LAMB2 FAM83B PPARGC1A DMRT2 NGFR

4.93e-06177109699500aed584f793aaf308f8afbf5d1c6a9b4ee55
ToppCellTCGA-Brain-Recurrent_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

USP17L7 USP17L2 SOX30 USP17L3 UNK

5.78e-0610410951360c9fcb9a68b385aa28dabd0715e71c4867a5b
ToppCellCOVID-19_Convalescent-PLT_4|World / Disease Group and Platelet Clusters

CEP85L MARCHF7 CHD9 JMJD1C GIGYF2 DUSP11

6.55e-0618610965954a1e3ffafb33f2a9bc87af3343f304fda4c92
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A DMRT2 NFAT5 PRDM16

6.55e-061861096a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 MXRA5 CASZ1 PIK3C2G NFAT5 PRDM16

7.40e-06190109611d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 FAM83B DMRT2 PIK3C2G NFAT5 PRDM16

7.85e-061921096f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TANC2 AMBRA1 ANKHD1 JMJD1C PTPRJ NFAT5

8.09e-061931096779276e775cb2492e8dd36436295a536084a6415
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A PTPRJ PATJ PRDM16

8.33e-06194109693c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A PTPRJ PATJ PRDM16

8.58e-0619510966477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A PTPRJ PATJ PRDM16

8.83e-061961096eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CASZ1 DMRT2 PTPRJ PIK3C2G PRDM16

3.41e-05150109587968ce885a4959616f0321f58517fe8029ba1b1
ToppCell356C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SIX4 ANAPC1 PATJ MYO15A XPR1

3.51e-0515110952dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CASZ1 PIK3C2G PATJ NFAT5 PRDM16

3.51e-05151109510da94037225a71844281ddcb395072250a78094
ToppCell356C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SIX4 ANAPC1 PATJ MYO15A XPR1

3.51e-05151109522afd8201eff8471da3456be065f2790de5e4bfe
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF28 ITIH2 KIAA1671 KCNN3 NFAT5

5.21e-0516410954cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A DMRT2 PTPRJ

5.21e-051641095d847d509bb1791638032ade6755d8164586b5bd5
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF28 ITIH2 KIAA1671 KCNN3 NFAT5

5.21e-0516410957a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCellPND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF28 ITIH2 KIAA1671 KCNN3 NFAT5

5.21e-0516410955e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCellPND10-Endothelial-Endothelial_lymphatic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF28 ITIH2 KIAA1671 KCNN3 NFAT5

5.21e-051641095f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A DMRT2 PTPRJ

5.52e-0516610956fe8db8d45177a78605681f22e04fa8d0594f2df
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF28 SIX4 FAM83B MYO15A DKKL1

6.18e-0517010956de3778e8257c3330db0780c59238ca501fe5059
ToppCellfacs-Lung-3m-Epithelial-airway_epithelial-club_cell-club_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGEF28 SIX4 FAM83B MYO15A DKKL1

6.18e-05170109560887da674ef1a735bad618235608312d8de63d3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

USP17L2 CASZ1 PPARGC1A PIK3C2G PRDM16

7.88e-051791095666072c0e8448dbaec1683d18368ec2502453f90
ToppCellNS-moderate-d_16-33-Epithelial-Ionocyte|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BNC2 LAMB2 PPARGC1A DMRT2 NGFR

8.09e-0518010958af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCellNS-critical-d_07-13-Epithelial-Ionocyte|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BNC2 LAMB2 PPARGC1A DMRT2 NGFR

8.75e-051831095ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BNC2 LAMB2 PPARGC1A DMRT2 NGFR

8.97e-05184109558d36577eff814d46d72f031f3533d71549e3d6e
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

CENPF LAMB2 EBF1 TJP1 NGFR

8.97e-0518410952e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINA3 LRWD1 ADGRA2 ZNF677 ZNF667

9.20e-0518510959878392d79734ab5bb977d7f4f5e2e079b9a5353
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CASZ1 DMRT2 PIK3C2G PRDM16

9.20e-0518510953d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCelldroplet-Liver-Npc-18m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VEZF1 LAMB2 EBF1 ZNF667 UNK

9.44e-05186109575258d88e23112fd1f0f7c71ef0366abb400d33e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 CASZ1 PPARGC1A PIK3C2G PRDM16

9.44e-051861095b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-6|TCGA-Stomach / Sample_Type by Project: Shred V9

USP17L1 PAIP1 SEC16A USP17L3

9.50e-05971094489f5e12eb67b1850f1f2d7d4b229df1f4ceefe3
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

B3GALNT1 CENPF ADGRA2 SEC16A QSER1

9.68e-0518710953c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellHealthy_donor-B_memory|World / disease group, cell group and cell class (v2)

PLEKHG7 CHD7 EBF1 ATRNL1 SNX22

9.68e-0518710954f68e3243071a4549c80aff8bff32c6ad892ee7f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CASZ1 FAM83B PIK3C2G PATJ PRDM16

9.68e-051871095f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EBF1 ADGRA2 SLC7A2 DMRT2 TJP1

9.68e-051871095a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLEKHG7 CHD7 EBF1 ATRNL1 SNX22

9.93e-051881095229108e7e3db49e1cfd747d69e338394139d95b3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CASZ1 PIK3C2G NFAT5 PRDM16

9.93e-051881095e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCellfacs-Lung-EPCAM-18m-Epithelial-Basal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIX4 PAK6 FAM83B DMRT2 NGFR

1.02e-041891095783c1db856f2defe6f3b8748dd0bc29a8102f6d1
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

CASZ1 PPARGC1A PATJ PRDM16 XPR1

1.02e-0418910959c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CASZ1 PPARGC1A PIK3C2G PRDM16

1.02e-0418910958ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

AMBRA1 PPARGC1A PATJ NFAT5 PRDM16

1.02e-041891095830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CASZ1 FAM83B PIK3C2G PATJ PRDM16

1.02e-041891095e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 BNC2 PPARGC1A PTPRJ PATJ

1.02e-0418910958c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellfacs-Lung-EPCAM-18m-Epithelial-respiratory_basal_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SIX4 PAK6 FAM83B DMRT2 NGFR

1.02e-04189109588b72fafbe58463543e0818f27f3dd9e5b4d34d2
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 BNC2 PPARGC1A PTPRJ PATJ

1.02e-0418910955d902a4660a27548764bf04c6de152b565da835c
ToppCellcritical-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

BNC2 LAMB2 PPARGC1A DMRT2 NGFR

1.04e-04190109505a2c3549b68f49081723bf35db14974274419d5
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTSF LAMB2 KIAA1671 TJP1 NGFR

1.04e-04190109581f8f2cddf4c51b879f315260cd1fca80355a371
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ARHGEF28 KIAA1671 PIK3C2G PATJ PRDM16

1.04e-041901095625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic-stroma-muscle|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTSF LAMB2 KIAA1671 TJP1 NGFR

1.04e-04190109520106e5213f6a7560554b8b4f84b23c5554ba975
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CASZ1 DMRT2 PIK3C2G NFAT5 PRDM16

1.04e-041901095b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 CASZ1 PPARGC1A PIK3C2G PRDM16

1.04e-0419010954836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell10x5'v1-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CTSF LAMB2 KIAA1671 TJP1 NGFR

1.04e-041901095877b544decf302e0d41be23dffa1861f79c70914
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

CASZ1 PPARGC1A PATJ PRDM16 XPR1

1.04e-041901095fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

MXRA5 CASZ1 PPARGC1A PIK3C2G PRDM16

1.10e-041921095d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ASXL1 HIVEP2 UBR4 SMURF1 NFAT5

1.10e-0419210956bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

PLEKHG7 CHD7 EBF1 ATRNL1 SNX22

1.10e-04192109572f936f03bb9b58c1ccaaf8270c07f5bbf2ac355
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PLEKHG7 CHD7 EBF1 ATRNL1 SNX22

1.10e-041921095dac61f0b374f6f9476eedce97f341f26c1bc037c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A PTPRJ PATJ

1.12e-04193109582e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MXRA5 PTPRJ PIK3C2G PATJ PRDM16

1.15e-04194109504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 BNC2 ARHGEF28 PTPRJ PATJ

1.15e-041941095e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellB_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

PLEKHG7 CHD7 EBF1 KCNN3 SNX22

1.15e-04194109522b87fe2bb84632ddcef8f1d7742021728e2246d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 FAM83B PTPRJ PATJ PRDM16

1.21e-041961095c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGEF28 CASZ1 PPARGC1A PTPRJ PATJ

1.21e-0419610956ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

CENPF LAMB2 PPARGC1A KCNN3 PRDM16

1.24e-04197109561749ccafeb938c310cff1de5ff924a1c794325a
ToppCellBronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 SLC7A2 TJP1 ZNF256 NGFR

1.24e-041971095dfeb4a0eb4dfba90f4a3e6ba31e0ab0e4aba5849
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

CENPF LAMB2 PPARGC1A KCNN3 PRDM16

1.24e-0419710959d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 LAMB2 EBF1 RTL1 TJP1

1.24e-0419710952872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EBF1 ADGRA2 SLC7A2 ANGPT4 PRDM16

1.27e-0419810957dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

B3GALNT1 ADGRA2 ZNF106 TJP1 KCNN3

1.30e-041991095eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SERPINA3 BNC2 HIVEP2 EBF1 NGFR

1.33e-0420010955ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCellTCGA-Ovary-Primary_Tumor|TCGA-Ovary / Sample_Type by Project: Shred V9

ZNF362 ZNF106 TRIM8 ZNF574

1.34e-04106109414f548be39cec604fbdae0382cbf434fa4049840
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

ZNF362 ZNF106 TRIM8 ZNF574

1.34e-041061094939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

ZNF362 ZNF106 TRIM8 ZNF574

1.34e-041061094e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Deep_layer_pyramidal_cells)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SPTBN5 PIK3C2G MYO15A

1.70e-04441093405ac4aeee539322cfe661c7531248f81271be8d
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6-Excitatory_Neuron.Slc17a7.Syt6-Slc24a2_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SPTBN5 PIK3C2G MYO15A

1.70e-04441093a2c99e8ca635590a1f167b68bc390e2aa01e26be
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CENPF LAMB2 TJP1 NGFR

2.30e-041221094489a01c71882be5a6d71a19d06574698988c20f6
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

UBR4 CHD9 ZMIZ1 SPTBN5

2.30e-0412210941ed865f0ecfe304fb86313ff51c04e9052357270
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_9|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPF LAMB2 TJP1 NGFR

2.30e-0412210947dabf8b4c34a3714f45c3a99c1aa159e2d0b7e9c
Diseasecongenital heart disease (implicated_via_orthology)

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 CHD9 USP17L10 CHD7 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

9.38e-296911218DOID:1682 (implicated_via_orthology)
Diseaseprimary ovarian insufficiency (implicated_via_orthology)

USP17L7 USP17L21 USP17L4 USP17L2 USP17L1 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 USP17L18 USP17L17 USP17L3 USP17L15 USP17L8 USP17L13

5.47e-284611216DOID:5426 (implicated_via_orthology)
Diseasevital capacity

BNC2 HIVEP2 CHD7 EBF1 ZMIZ1 SIX4 JMJD1C CASZ1 ARMS2 TRIM66 ZNF106 ZNF263 DMRT2 ANGPT4 CAPRIN2 PATJ NFAT5

4.22e-06123611217EFO_0004312
Diseasechildhood trauma measurement, alcohol consumption measurement

TANC2 PCDHGA9 MARCHF7 PCDHGA8

1.57e-04711124EFO_0007878, EFO_0007979
DiseaseFEV/FEC ratio

BNC2 ASXL1 HIVEP2 ARHGEF28 SOX30 JMJD1C FAM83B SPTBN5 PPARGC1A ZNF106 ANAPC1 KCNN3 MYO15A PRDM16

2.33e-04122811214EFO_0004713
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD9 CHD7

2.96e-0471122DOID:0050834 (implicated_via_orthology)
Diseasefacial morphology measurement

BNC2 GTF2A1L CASZ1 PPARGC1A ZNF106 DMRT2 ANAPC1 PRDM16

4.14e-044661128EFO_0007841
Diseasemean platelet volume

HIVEP2 PCDHGA9 SMURF1 CHD9 CHD7 EBF1 ZMIZ1 JMJD1C PTPRJ PRDM16 PCDHGA8 SMAD5

5.05e-04102011212EFO_0004584
DiseaseAntihypertensive use measurement

HIVEP2 EBF1 CASZ1 ARMS2 NFAT5 PRDM16

5.36e-042651126EFO_0009927
DiseaseProstatic Neoplasms

SERPINA3 CENPF LAMB2 CHD7 PAK6 CASZ1 NGFR EIF3A PATJ

5.80e-046161129C0033578
DiseaseMalignant neoplasm of prostate

SERPINA3 CENPF LAMB2 CHD7 PAK6 CASZ1 NGFR EIF3A PATJ

5.80e-046161129C0376358
Diseasewaist-hip ratio

EBF1 ZMIZ1 KCNB2 JMJD1C KIAA2013 TRIM66 SLC7A2 CAPRIN2 TRIM8 KCNN3 PATJ NFAT5 PRDM16

7.75e-04122611213EFO_0004343
Diseaseelectrocardiography

CEP85L EBF1 ZMIZ1 JMJD1C CASZ1 PPARGC1A KCNN3 PRDM16

9.56e-045301128EFO_0004327
DiseaseQRS duration

THEMIS CEP85L UBR4 PPARGC1A PTPRJ PRDM16

9.86e-042981126EFO_0005055
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

HIVEP2 SMAD5

1.08e-03131122DOID:0050787 (implicated_via_orthology)
Diseasehypertension

EBF1 CASZ1 KIAA2013 ARMS2 PTPRJ PRDM16

1.15e-033071126EFO_0000537
Diseasecongenital hypothyroidism (biomarker_via_orthology)

PPARGC1A NGFR

1.26e-03141122DOID:0050328 (biomarker_via_orthology)
DiseaseAlzheimer's disease (implicated_via_orthology)

HIVEP2 PITRM1 PPARGC1A

1.34e-03571123DOID:10652 (implicated_via_orthology)
Diseasebipolar disorder

CTSF HIVEP2 ZNF391 ZMIZ1 ANKHD1 TRIM8 NGFR KCNN3

1.64e-035771128MONDO_0004985
Diseaselower body strength measurement

PCNX2 KIAA1671

1.65e-03161122EFO_0007999
Diseasecataract

CASZ1 ARMS2 CAPRIN2 NFAT5

2.08e-031411124MONDO_0005129
DiseaseC-reactive protein measurement

BNC2 ARHGEF28 CHD7 EBF1 ZMIZ1 KCNB2 ZNF106 SEC16A KCNN3 QSER1 PATJ NFAT5

2.12e-03120611212EFO_0004458
Diseasevenous thromboembolism, fibrinogen measurement

CHD9 JMJD1C PTPRJ

2.14e-03671123EFO_0004286, EFO_0004623
Diseasediet measurement, HOMA-B

PCNX2 NFAT5

2.34e-03191122EFO_0004469, EFO_0008111
Diseasemigraine disorder

CENPF AMBRA1 CASZ1 ARMS2 ZNF106 PRDM16

2.46e-033571126MONDO_0005277
Diseasep-tau measurement

KCNB2 EXOC1 PATJ

2.62e-03721123EFO_0004763
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

BNC2 EBF1 KCNB2 TRIM66 PATJ NFAT5

2.70e-033641126EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasegranulocyte count

MARCHF7 CHD7 ZMIZ1 JMJD1C PTPRJ

2.89e-032541125EFO_0007987

Protein segments in the cluster

PeptideGeneStartEntry
TQRRFQQPQHHLTLS

ARMS2

86

P0C7Q2
HQSFQHLLRTLNQSS

SERPINA3

116

P01011
LRSSQPNVSALHCQH

ADGRA2

731

Q96PE1
LENSNPSSIHHFENI

BNC2

301

Q6ZN30
SHCLDHINPNNNLVN

CASZ1

1201

Q86V15
PHSSENNSNLSRGHL

AMBRA1

551

Q9C0C7
QANDHHPRNLSSPFI

SLC7A2

636

P52569
HPSTNQNQTKLTHFD

CHD7

56

Q9P2D1
RTFHALPSHFQQQLL

ASXL1

271

Q8IXJ9
HHTPDTRTQAQQTQD

ZFYVE19

241

Q96K21
HHQRPSGTQSIQAQL

QSER1

191

Q2KHR3
AQNGSRHSQHSFLEP

GSG1L2

241

A8MUP6
QLSPNHHFSLDVQTG

PCDHGA8

171

Q9Y5G5
HQEFLFVNQPHSSSQ

PIK3C2G

21

O75747
LHFLQCHSKNNSPQD

LRWD1

276

Q9UFC0
PHDSNSHRPQLQAFI

ARHGEF28

1661

Q8N1W1
FSSRSHQERLQNHPK

ANAPC1

1821

Q9H1A4
NIQTSESHPLRQFHF

PTPRJ

1186

Q12913
EISAPQNFQHRVHTS

PAK6

11

Q9NQU5
PLSENHNNNTFLKHL

KIAA1671

706

Q9BY89
PHTSVTDVTQNNFHN

ITIH2

506

P19823
SQHRQQTQALSPHQA

MYO15A

3386

Q9UKN7
SSLSHLALAHQQQQQ

JMJD1C

821

Q15652
TLREHSNCSHQNPFL

B3GALNT1

66

O75752
QEHQLGNNTLSSHLQ

DKKL1

91

Q9UK85
HHNTPAQSFANRLAQ

FAM83B

436

Q5T0W9
EHITNHRNPSNNRQI

PCNX2

111

A6NKB5
HPSSRQGSQLNLNDH

KCNN3

121

Q9UGI6
QLSPNHHFSLNVQTG

PCDHGA9

171

Q9Y5G4
QHHLNSQVSLLSLNP

FAM205A

251

Q6ZU69
DNPHSHRIQNVVTSF

LAMB2

101

P55268
QHSQRHSSTNLLQEG

ASIC3

476

Q9UHC3
LQQSSHSQAQLFHPQ

NFAT5

1061

O94916
SHHLTISPQSGNFRQ

PAIP1

226

Q9H074
TQNHANHNHRIRTNP

PPARGC1A

166

Q9UBK2
SLNSNNFQILHSSHP

CHD9

331

Q3L8U1
HEQLNNTSSSSPQHL

KCNB2

521

Q92953
TFHSLCHQQQLQNPA

CABIN1

861

Q9Y6J0
LRHNPFHSLFQQTLT

DMRT2

466

Q9Y5R5
APRHFHTQTQSLQQS

DUSP11

296

O75319
PNRARNNTHSNLHTS

GIGYF2

1026

Q6Y7W6
PHELSTSQNDNAHLQ

CENPF

1276

P49454
SQIQRHHNQSTAINL

EIF3A

206

Q14152
HHNQSTAINLNNPES

EIF3A

211

Q14152
LSQNHPDNRNETFSS

CTSF

151

Q9UBX1
HNSSLLQDQQHSLRQ

ANGPT4

246

Q9Y264
QATTVPSNHRNNHIR

CEP85L

41

Q5SZL2
RHHTAINFIANPEQS

ATRNL1

1126

Q5VV63
RNHNQLPALANTSVH

EBF1

416

Q9UH73
HSQHGESQRALSPLQ

CAPRIN2

91

Q6IMN6
LNTSSTNHQLPSEHQ

MARCHF7

196

Q9H992
QISESNHLIHLSNTN

EXOC1

251

Q9NV70
PQFQADLSNLHLNRH

MIER2

201

Q8N344
NALHSQAHRGLQFTP

RTL1

1176

A6NKG5
FTDPSNLQRHIRSQH

PRDM16

346

Q9HAZ2
IFSQHLQNRLLPDHT

PITRM1

216

Q5JRX3
SHSFESANHPLLQQL

SIX4

171

Q9UIU6
KTARTQQYPHLHQQN

TANC2

1851

Q9HCD6
DHNNRTTQFTDPRLH

SMURF1

326

Q9HCE7
QSQHPAAHTVREQLQ

SPTBN5

1276

Q9NRC6
QRFTGPSQTDTHQLH

SOX30

511

O94993
HSLLVQFRNLSHNEP

SMAD5

151

Q99717
HQQLSDPSTFSQHQP

ANKHD1

2426

Q8IWZ3
LIFELNPRSNLSHQH

XPR1

301

Q9UBH6
NPRSNLSHQHLFEIA

XPR1

306

Q9UBH6
SQSLQQRSHHLENPF

ZNF667

316

Q5HYK9
SPLHHAQQLQLFSQQ

TNRC18

891

O15417
RNHQTHSFNLPLSQE

THEMIS

156

Q8N1K5
KNHHPEQQSSLLNLS

USP17L3

476

A6NCW0
FSNSSNLVQHQRIHT

ZNF880

221

Q6PDB4
SHHQQQAAQNSLLPL

VEZF1

16

Q14119
KNHHPEQQSSLLNLS

USP17L4

476

A6NCW7
AQTHSLLQHQPLQLT

MRPL10

216

Q7Z7H8
HLANNSDPESTFRQN

SEC16A

291

O15027
FTLQLPHSLHQTLQS

GTF2A1L

66

Q9UNN4
SQSLHDQQPHTQTAS

NGFR

311

P08138
LAINHTPLDQNISHQ

PATJ

186

Q8NI35
QLFLSPHQLQQHLRS

ZNF574

316

Q6ZN55
QSSNLTNHQRIHSGE

ZNF256

586

Q9Y2P7
KNHHPEQQSSLLNLS

USP17L18

476

D6R9N7
RHFQEHPRQQLATSS

MOSPD3

166

O75425
KNHHPEQQSSLLNLS

USP17L5

476

A8MUK1
KNHHPEQQSSLLNLS

USP17L21

476

D6R901
KNHHPEQQSSLLNLS

USP17L13

476

C9JLJ4
QQPAQHHRDVLLSSS

ZNF281

186

Q9Y2X9
KNHHPEQQSSLLNLS

USP17L1

476

Q7RTZ2
FPNHTDNLNSSQRLS

RALGAPB

1306

Q86X10
SSQQHQRPVLSFHVD

SNX22

131

Q96L94
FNIPSSFQIHQRNHT

ZNF124

131

Q15973
SNLTNHQRIHSGQRP

ZNF677

276

Q86XU0
FDNQHSQDLDSRQHP

TJP1

1106

Q07157
AFSQTSNLTQHQRIH

ZNF471

551

Q9BX82
SQSPQLTQHQRIHTG

ZNF251

331

Q9BRH9
KNHHPEQQSSLLNLS

USP17L24

476

Q0WX57
AFTQLSNLQSHQRQH

ZNF362

321

Q5T0B9
KNHHPEQQSSLLNLS

USP17L7

476

P0C7H9
KNHHPEQQSSLLNLS

USP17L8

476

P0C7I0
HQASLRQQEGHFLPS

PLEKHG7

146

Q6ZR37
QRERHHQPQTCTLSQ

USP31

586

Q70CQ4
QQSYHTQPRLVRQHN

HIVEP2

871

P31629
QSHVQTHLQQPSTAR

TRIM8

116

Q9BZR9
QSHQSPVAQQEALSH

TRIM66

291

O15016
ILRTQNHILTNHPNS

UBR4

3496

Q5T4S7
VSLSSHFLQQPQGHL

UNK

581

Q9C0B0
KNHHPEQQSSLLNLS

USP17L15

476

C9J2P7
KNHHPEQQSSLLNLS

USP17L17

476

D6RBQ6
KQHLLTDHTNPNFQT

ZNF106

1831

Q9H2Y7
FNHSPNPSKHQRNEI

ZNF195

391

O14628
KNHHPEQQSSLLNLS

USP17L2

476

Q6R6M4
KNHHPEQQSSLLNLS

USP17L20

476

D6RJB6
HLQNPANFHNAATEL

ZMIZ1

21

Q9ULJ6
KNHHPEQQSSLLNLS

USP17L10

476

C9JJH3
KNHHPEQQSSLLNLS

USP17L11

476

C9JVI0
TNLSQHQRTHTQERP

ZNF391

206

Q9UJN7
NFSNNSNLIRHQRIH

ZNF263

386

O14978
NHLQFQADPDVLHNS

KIAA2013

466

Q8IYS2
NRFLHPQGSLTIQHA

MXRA5

2786

Q9NR99
QQHNSEHARLQVPTS

MYOT

211

Q9UBF9