Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 PGA4 ERVK-8 ERVK-19 ERVK-7 ERVK-25 PGA5 PGA3	1.48e-13	37	60	8	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 PGA4 ERVK-8 ERVK-19 ERVK-7 ERVK-25 PGA5 PGA3	1.86e-13	38	60	8	GO:0070001
GeneOntologyMolecularFunction	endopeptidase activity	PCSK5 ERVK-6 PGA4 ERAP2 ERVK-8 PAPPA ERVK-19 ERVK-7 ERVK-25 PGA5 PGA3	5.40e-08	430	60	11	GO:0004175
GeneOntologyMolecularFunction	peptidase activity	PCSK5 ERVK-6 PGA4 ERAP2 ERVK-8 PAPPA ERVK-19 ERVK-7 ERVK-25 PGA5 PGA3 OTUD7B	4.57e-07	654	60	12	GO:0008233
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-8 ERVK-7	4.18e-06	11	60	3	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	9.17e-06	14	60	3	GO:0003964
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-8 ERVK-7	3.30e-05	21	60	3	GO:0035613
GeneOntologyMolecularFunction	gap junction channel activity	GJA4 GJD2 GJD4	5.66e-05	25	60	3	GO:0005243
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	1.86e-04	37	60	3	GO:0016891
GeneOntologyMolecularFunction	wide pore channel activity	GJA4 GJD2 GJD4	1.86e-04	37	60	3	GO:0022829
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-8 ERVK-7	2.02e-04	38	60	3	GO:0034061
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-8 ERVK-7	3.57e-04	46	60	3	GO:0016893
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP2 LRP1B	1.04e-03	16	60	2	GO:0005041
GeneOntologyMolecularFunction	adenylate cyclase activity	ADCY4 ADCY5	1.32e-03	18	60	2	GO:0004016
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-8 ERVK-7	1.73e-03	79	60	3	GO:0004521
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP2 LRP1B	1.80e-03	21	60	2	GO:0030228
GeneOntologyMolecularFunction	cyclase activity	ADCY4 ADCY5	2.35e-03	24	60	2	GO:0009975
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	ADCY4 ADCY5	2.55e-03	25	60	2	GO:0016849
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-8 ERVK-7	6.56e-06	13	60	3	GO:0015074
GeneOntologyBiologicalProcess	folate transmembrane transport	SLC25A32 LRP2	8.27e-05	5	60	2	GO:0098838
GeneOntologyBiologicalProcess	cell-cell fusion	ERVK-6 ERVFC1 ERVK-8 ERVK-19	1.10e-04	85	60	4	GO:0140253
GeneOntologyBiologicalProcess	syncytium formation by plasma membrane fusion	ERVK-6 ERVFC1 ERVK-8 ERVK-19	1.10e-04	85	60	4	GO:0000768
GeneOntologyBiologicalProcess	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	ADCY4 FSHR CHRM4 ADCY5	1.15e-04	86	60	4	GO:0007193
GeneOntologyBiologicalProcess	syncytium formation	ERVK-6 ERVFC1 ERVK-8 ERVK-19	1.31e-04	89	60	4	GO:0006949
GeneOntologyCellularComponent	multivesicular body lumen	PGA4 PGA5 PGA3	7.80e-07	7	60	3	GO:0097486
GeneOntologyCellularComponent	late endosome lumen	PGA4 PGA5 PGA3	3.65e-06	11	60	3	GO:0031906
GeneOntologyCellularComponent	endosome lumen	PGA4 LRP2 PGA5 PGA3	6.96e-06	43	60	4	GO:0031904
GeneOntologyCellularComponent	connexin complex	GJA4 GJD2 GJD4	3.33e-05	22	60	3	GO:0005922
GeneOntologyCellularComponent	gap junction	GJA4 GJD2 GJD4	1.63e-04	37	60	3	GO:0005921
Domain	ASP_PROTEASE	ERVK-6 PGA4 PGA5 PGA3	3.52e-08	12	56	4	PS00141
Domain	Aspartic_peptidase_AS	ERVK-6 PGA4 PGA5 PGA3	5.08e-08	13	56	4	IPR001969
Domain	TIL_dom	VWF LRP2 TECTA MUC6	7.09e-08	14	56	4	IPR002919
Domain	Aspartic_peptidase_N	PGA4 PGA5 PGA3	8.86e-07	7	56	3	IPR012848
Domain	A1_Propeptide	PGA4 PGA5 PGA3	8.86e-07	7	56	3	PF07966
Domain	Aspartic_peptidase_A1	PGA4 PGA5 PGA3	3.02e-06	10	56	3	IPR001461
Domain	PEPTIDASE_A1	PGA4 PGA5 PGA3	3.02e-06	10	56	3	IPR033121
Domain	Asp	PGA4 PGA5 PGA3	3.02e-06	10	56	3	PF00026
Domain	PEPTIDASE_A1	PGA4 PGA5 PGA3	3.02e-06	10	56	3	PS51767
Domain	TIL	VWF TECTA MUC6	5.51e-06	12	56	3	PF01826
Domain	-	PGA4 PGA5 PGA3	5.51e-06	12	56	3	2.40.70.10
Domain	C8	VWF TECTA MUC6	5.51e-06	12	56	3	PF08742
Domain	Unchr_dom_Cys-rich	VWF TECTA MUC6	7.15e-06	13	56	3	IPR014853
Domain	C8	VWF TECTA MUC6	7.15e-06	13	56	3	SM00832
Domain	VWD	VWF TECTA MUC6	1.39e-05	16	56	3	SM00216
Domain	VWF_type-D	VWF TECTA MUC6	1.39e-05	16	56	3	IPR001846
Domain	VWFD	VWF TECTA MUC6	1.39e-05	16	56	3	PS51233
Domain	VWD	VWF TECTA MUC6	1.39e-05	16	56	3	PF00094
Domain	Peptidase_aspartic_dom	PGA4 PGA5 PGA3	1.69e-05	17	56	3	IPR021109
Domain	CONNEXINS_1	GJA4 GJD2 GJD4	2.39e-05	19	56	3	PS00407
Domain	VWC_out	VWF TECTA MUC6	2.39e-05	19	56	3	SM00215
Domain	CONNEXINS_2	GJA4 GJD2 GJD4	2.81e-05	20	56	3	PS00408
Domain	Connexin	GJA4 GJD2 GJD4	2.81e-05	20	56	3	IPR000500
Domain	Connexin_CCC	GJA4 GJD2 GJD4	2.81e-05	20	56	3	IPR019570
Domain	Connexin_N	GJA4 GJD2 GJD4	2.81e-05	20	56	3	IPR013092
Domain	Connexin	GJA4 GJD2 GJD4	2.81e-05	20	56	3	PF00029
Domain	Connexin_CCC	GJA4 GJD2 GJD4	2.81e-05	20	56	3	SM01089
Domain	Connexin_CS	GJA4 GJD2 GJD4	2.81e-05	20	56	3	IPR017990
Domain	CNX	GJA4 GJD2 GJD4	2.81e-05	20	56	3	SM00037
Domain	Ephrin_rec_like	EPHB3 PCSK5 ELAPOR1	5.60e-05	25	56	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB3 PCSK5 ELAPOR1	5.60e-05	25	56	3	IPR011641
Domain	Growth_fac_rcpt_	EPHB3 PCSK5 ELAPOR1 LRP2 LRP1B	1.03e-04	156	56	5	IPR009030
Domain	Adcy_conserved_dom	ADCY4 ADCY5	1.31e-04	6	56	2	IPR009398
Domain	DUF1053	ADCY4 ADCY5	1.31e-04	6	56	2	PF06327
Domain	AC_N	ADCY4 ADCY5	2.44e-04	8	56	2	IPR032628
Domain	Adcy	ADCY4 ADCY5	2.44e-04	8	56	2	IPR030672
Domain	AC_N	ADCY4 ADCY5	2.44e-04	8	56	2	PF16214
Domain	VWF_dom	VWF TECTA MUC6	2.70e-04	42	56	3	IPR001007
Domain	EGF	PCSK5 BRINP2 LRP2 TECTA LRP1B	6.85e-04	235	56	5	SM00181
Domain	Ldl_recept_b	LRP2 LRP1B	7.85e-04	14	56	2	PF00058
Domain	LDLRB	LRP2 LRP1B	7.85e-04	14	56	2	PS51120
Domain	LY	LRP2 LRP1B	9.04e-04	15	56	2	SM00135
Domain	LDLR_classB_rpt	LRP2 LRP1B	9.04e-04	15	56	2	IPR000033
Domain	A/G_cyclase_CS	ADCY4 ADCY5	1.17e-03	17	56	2	IPR018297
Domain	Nucleotide_cyclase	ADCY4 ADCY5	1.31e-03	18	56	2	IPR029787
Domain	-	ADCY4 ADCY5	1.31e-03	18	56	2	3.30.70.1230
Domain	GUANYLATE_CYCLASE_1	ADCY4 ADCY5	1.46e-03	19	56	2	PS00452
Domain	Guanylate_cyc	ADCY4 ADCY5	1.46e-03	19	56	2	PF00211
Domain	GUANYLATE_CYCLASE_2	ADCY4 ADCY5	1.46e-03	19	56	2	PS50125
Domain	A/G_cyclase	ADCY4 ADCY5	1.46e-03	19	56	2	IPR001054
Domain	CYCc	ADCY4 ADCY5	1.46e-03	19	56	2	SM00044
Domain	CT	VWF MUC6	1.96e-03	22	56	2	SM00041
Domain	Cys_knot_C	VWF MUC6	2.53e-03	25	56	2	IPR006207
Domain	CTCK_2	VWF MUC6	2.53e-03	25	56	2	PS01225
Domain	cEGF	LRP2 LRP1B	2.74e-03	26	56	2	IPR026823
Domain	cEGF	LRP2 LRP1B	2.74e-03	26	56	2	PF12662
Domain	VWC	VWF TECTA	5.79e-03	38	56	2	SM00214
Domain	VWFC_2	VWF TECTA	5.79e-03	38	56	2	PS50184
Pathway	WP_GASTRIC_ACID_PRODUCTION	PGA4 PGA5 MUC6 PGA3	3.52e-08	11	47	4	M39726
Pathway	KEGG_MEDICUS_REFERENCE_FSHR_GNAS_PKA_SIGNALING_PATHWAY	ADCY4 FSHR ADCY5	1.89e-05	16	47	3	M47650
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	GJA4 ADCY4 GJD2 CHRM4 ADCY5	1.24e-04	147	47	5	MM15854
Pathway	REACTOME_SURFACTANT_METABOLISM	PGA4 PGA5 PGA3	1.32e-04	30	47	3	M27566
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	GJA4 ADCY4 GJD2 CHRM4 ADCY5	1.41e-04	151	47	5	M39329
Pathway	REACTOME_GAP_JUNCTION_ASSEMBLY	GJA4 GJD2 GJD4	1.61e-04	32	47	3	MM14730
Pathway	REACTOME_GAP_JUNCTION_ASSEMBLY	GJA4 GJD2 GJD4	2.70e-04	38	47	3	M14981
Pathway	REACTOME_GAP_JUNCTION_TRAFFICKING_AND_REGULATION	GJA4 GJD2 GJD4	4.18e-04	44	47	3	MM14606
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY4 ADCY5	4.81e-04	10	47	2	M19522
Pathway	REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY	ADCY4 ADCY5	4.81e-04	10	47	2	MM14668
Pathway	REACTOME_GAP_JUNCTION_TRAFFICKING_AND_REGULATION	GJA4 GJD2 GJD4	6.47e-04	51	47	3	M26972
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY4 ADCY5	9.65e-04	14	47	2	MM14669
Pathway	REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY	ADCY4 ADCY5	9.65e-04	14	47	2	M750
Pathway	KEGG_MEDICUS_REFERENCE_EP_NE_ADRB_CAMP_SIGNALING_PATHWAY	ADCY4 ADCY5	1.11e-03	15	47	2	M47794
Pathway	PID_LPA4_PATHWAY	ADCY4 ADCY5	1.11e-03	15	47	2	M56
Pathway	KEGG_MEDICUS_REFERENCE_PTH_PTH1R_PKA_SIGNALING_PATHWAY	ADCY4 ADCY5	1.11e-03	15	47	2	M47504
Pathway	WP_MAJOR_RECEPTORS_TARGETED_BY_EPINEPHRINE_AND_NOREPINEPHRINE	ADCY4 ADCY5	1.27e-03	16	47	2	M39849
Pathway	KEGG_MEDICUS_REFERENCE_LHCGR_GNAS_PKA_SIGNALING_PATHWAY	ADCY4 ADCY5	1.27e-03	16	47	2	M47645
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY4 ADCY5	1.27e-03	16	47	2	MM14492
Pathway	REACTOME_PKA_ACTIVATION_IN_GLUCAGON_SIGNALLING	ADCY4 ADCY5	1.43e-03	17	47	2	M26995
Pathway	KEGG_MEDICUS_REFERENCE_CX3CR1_GNAI_AC_PKA_SIGNALING_PATHWAY	ADCY4 ADCY5	1.43e-03	17	47	2	M47544
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	ADCY4 FSHR TAAR5 ADCY5	1.82e-03	157	47	4	M4904
Pathway	REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB	ADCY4 ADCY5	1.99e-03	20	47	2	M759
Pubmed	Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.	ERVK-6 ERVFC1 ERVK-8 ERVK-19	3.92e-09	12	60	4	14557543
Pubmed	Close linkage of human chromosomal pepsinogen A genes.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	3017318
Pubmed	Serum pepsinogen test for early detection of gastric cancer in a European country.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	21989121
Pubmed	Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	9855083
Pubmed	Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	9797498
Pubmed	The glomerular sieving of pepsinogen A and C in man.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2478370
Pubmed	Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	3815274
Pubmed	Pepsinogens: physiology, pharmacology pathophysiology and exercise.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	10675278
Pubmed	The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	7926498
Pubmed	Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	3780036
Pubmed	Crystal structure of human pepsinogen A.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	9561228
Pubmed	The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	21455714
Pubmed	Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	19800305
Pubmed	Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2901984
Pubmed	Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	3839486
Pubmed	Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	24170207
Pubmed	Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	3467902
Pubmed	The pepsinogens of human gastric mucosa.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	4586732
Pubmed	Relationships between the human pepsinogen DNA and protein polymorphisms.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	3014868
Pubmed	Genomic structure and evolution of the human pepsinogen A multigene family.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2892778
Pubmed	The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	24383519
Pubmed	Gene structures of pepsinogens A and C.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	1455184
Pubmed	Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2831884
Pubmed	The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2799289
Pubmed	CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	19872561
Pubmed	Human pepsinogen A (PGA): an informative gene complex located at 11q13.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	1968039
Pubmed	Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2032552
Pubmed	Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	8053437
Pubmed	Analysis of the promoter of a human pepsinogen A gene.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	1812762
Pubmed	O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	7923573
Pubmed	Family and population studies on the human pepsinogen A multigene family.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2566575
Pubmed	Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	9061458
Pubmed	Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	12588289
Pubmed	Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2229438
Pubmed	Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	25314140
Pubmed	Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	19890696
Pubmed	Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	23897256
Pubmed	An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	11566730
Pubmed	The effect of acute and chronic protein loading on urinary pepsinogen A excretion.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	1956484
Pubmed	Transcription regulation of human and porcine pepsinogen A.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	8540382
Pubmed	Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	8244094
Pubmed	Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	21407214
Pubmed	Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	22992016
Pubmed	The role of serum pepsinogen in the detection of gastric cancer.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	20981206
Pubmed	Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	6774973
Pubmed	Gastric chief cell-specific transcription of the pepsinogen A gene.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	8504820
Pubmed	Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	21970995
Pubmed	Primary structure of human pepsinogen gene.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	6300126
Pubmed	Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	22304859
Pubmed	Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	24004680
Pubmed	Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	8038355
Pubmed	Serum pepsinogens in gastric cancer screening.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	20428942
Pubmed	Human pepsinogen A isozymogen patterns in serum and gastric mucosa.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	2227273
Pubmed	The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	9525001
Pubmed	Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	7886402
Pubmed	Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	23034090
Pubmed	A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	24125879
Pubmed	Serum pepsinogen and gastric cancer screening.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	17379991
Pubmed	Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	8751234
Pubmed	Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	3554488
Pubmed	Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	21547904
Pubmed	Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.	PGA4 PGA5 PGA3	4.88e-09	3	60	3	23521833
Pubmed	Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.	PGA4 PGA5 PGA3	1.95e-08	4	60	3	23047493
Pubmed	Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.	PGA4 PGA5 PGA3	1.95e-08	4	60	3	11915945
Pubmed	Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.	PGA4 PGA5 PGA3	1.95e-08	4	60	3	8322031
Pubmed	Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.	PGA4 PGA5 PGA3	1.95e-08	4	60	3	17136346
Pubmed	Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.	PGA4 PGA5 PGA3	1.95e-08	4	60	3	12698190
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-19 ERVK-7	4.87e-08	5	60	3	12629516
Pubmed	Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.	PGA4 PGA5 PGA3	4.87e-08	5	60	3	22066020
Pubmed	Preferential expression of connexin37 and connexin40 in the endothelium of the portal veins during mouse liver development.	GJA4 VWF PECAM1	2.72e-07	8	60	3	16505993
Pubmed	Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects.	VWF PECAM1 PLXND1	5.81e-07	10	60	3	18992737
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-8 ERVK-19 ERVK-7 ERVK-25	6.29e-07	94	60	5	21542922
Pubmed	Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.	GJA4 VWF PECAM1	2.69e-06	16	60	3	26953188
Pubmed	Crystal structure of human pepsin and its complex with pepstatin.	PGA4 PGA5	2.93e-06	2	60	2	7663352
Pubmed	Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.	PGA4 PGA5	2.93e-06	2	60	2	2714789
Pubmed	Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.	ERVK-6 ERVK-19	2.93e-06	2	60	2	9060628
Pubmed	Activation of human pepsinogens.	PGA4 PGA5	2.93e-06	2	60	2	3197840
Pubmed	Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.	ERVK-6 ERVK-19	2.93e-06	2	60	2	9460924
Pubmed	PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis.	PECAM1 PLXND1	2.93e-06	2	60	2	12412018
Pubmed	Isolation of human, swine, and rat prepepsinogens and calf preprochymosin, and determination of the primary structures of their NH2-terminal signal sequences.	PGA4 PGA5	2.93e-06	2	60	2	2415509
Pubmed	Critical role of the transcriptional repressor neuron-restrictive silencer factor in the specific control of connexin36 in insulin-producing cell lines.	GJD2 REST	2.93e-06	2	60	2	14565956
Pubmed	Association of PLXND1 with a novel subtype of anomalous pulmonary venous return.	PECAM1 PLXND1	2.93e-06	2	60	2	34791216
Pubmed	Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.	PGA4 PGA5 PGA3	3.91e-06	18	60	3	36057966
Pubmed	An expression atlas of connexin genes in the mouse.	GJA4 GJD2 GJD4	3.91e-06	18	60	3	15081111
Pubmed	The novel mouse connexin39 gene is expressed in developing striated muscle fibers.	GJA4 GJD2 GJD4	3.91e-06	18	60	3	15466892
Pubmed	An update on connexin genes and their nomenclature in mouse and man.	GJA4 GJD2 GJD4	4.64e-06	19	60	3	14681012
Pubmed	PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development.	VWF PECAM1 PLXND1	4.64e-06	19	60	3	15239958
Pubmed	Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice.	EPHB3 GJA4 PECAM1	4.64e-06	19	60	3	15184386
Pubmed	Tie2 regulates endocardial sprouting and myocardial trabeculation.	GJA4 VWF PECAM1 PLXND1	6.00e-06	68	60	4	31112136
Pubmed	Genome-wide association study to identify single nucleotide polymorphisms (SNPs) associated with the development of erectile dysfunction in African-American men after radiotherapy for prostate cancer.	DCAF8L1 FSHR LRP1B	8.43e-06	23	60	3	20932654
Pubmed	The endothelial cell markers von Willebrand Factor (vWF), CD31 and CD34 are lost in glomerulonephritis and no longer correlate with the morphological indices of glomerular sclerosis, interstitial fibrosis, activity and chronicity.	VWF PECAM1	8.77e-06	3	60	2	20675279
Pubmed	The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.	TM2D1 LRP1B	8.77e-06	3	60	2	15126508
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-19	8.77e-06	3	60	2	10516026
Pubmed	Targeted disruption of cubilin reveals essential developmental roles in the structure and function of endoderm and in somite formation.	PECAM1 LRP2	8.77e-06	3	60	2	16787536
Pubmed	A comparative study on the NH2-terminal amino acid sequences and some other properties of six isozymic forms of human pepsinogens and pepsins.	PGA4 PGA5	8.77e-06	3	60	2	2515193
Pubmed	Inducible coexpression of connexin37 or connexin40 with connexin43 selectively affects intercellular molecular transfer.	GJA4 GJD4	8.77e-06	3	60	2	22729648
Pubmed	Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus.	PECAM1 PRDM6	8.77e-06	3	60	2	27181681
Pubmed	Dissecting coronary angiogenesis: 3D co-culture of cardiomyocytes with endothelial or mesenchymal cells.	VWF PECAM1	8.77e-06	3	60	2	19769963
Pubmed	Definitive hematopoiesis requires the mixed-lineage leukemia gene.	PECAM1 KMT2A	1.75e-05	4	60	2	15030765
Pubmed	Vascular endocan is preferentially expressed in tumor endothelium.	VWF PECAM1	1.75e-05	4	60	2	16956626
Cytoband	11q23	SCN2B KMT2A	9.95e-04	36	59	2	11q23
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	PGA4 SLC22A24 PGA5 PGA3	1.03e-03	345	59	4	chr11q12
Cytoband	11q12.2	PGA4 PGA3	1.17e-03	39	59	2	11q12.2
Cytoband	14q12	ADCY4 TSSK4	2.31e-03	55	59	2	14q12
Cytoband	Ensembl 112 genes in cytogenetic band chr11q23	SCN2B KMT2A TECTA	2.90e-03	220	59	3	chr11q23
Cytoband	19q13.3	SIGLEC7 MED25	5.05e-03	82	59	2	19q13.3
GeneFamily	Gap junction proteins	GJA4 GJD2 GJD4	1.87e-05	22	43	3	314
GeneFamily	Adenylate cyclases\|Deafness associated genes	ADCY4 ADCY5	2.46e-04	10	43	2	53
GeneFamily	Low density lipoprotein receptors	LRP2 LRP1B	4.24e-04	13	43	2	634
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2A PRDM6	2.95e-03	34	43	2	487
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	5.14e-08	166	54	6	7a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	5.14e-08	166	54	6	bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	7.27e-08	176	54	6	77516048aefbe1f48e825052756df0c310c1c486
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	7.27e-08	176	54	6	96779273b94345250cf53ba671203345b43d9e00
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	8.58e-08	181	54	6	4d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	9.16e-08	183	54	6	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	P28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	9.46e-08	184	54	6	8ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.04e-07	187	54	6	66ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.07e-07	188	54	6	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.11e-07	189	54	6	d17e8467699c7ca7694a313c26111f085df5204e
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.11e-07	189	54	6	feedac2751ed770f80bc56fec31662b5b3826f58
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.11e-07	189	54	6	9da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.14e-07	190	54	6	d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.14e-07	190	54	6	3346bfd0474828b3729cffa9f4cc57b04dd30443
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.14e-07	190	54	6	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.14e-07	190	54	6	eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.18e-07	191	54	6	b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.18e-07	191	54	6	27f23c2254b610abac1a88d0fecff305addde9da
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.18e-07	191	54	6	d162917816dd2e4767c97447c1cddae9397713ab
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.18e-07	191	54	6	3307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCell	P03-Endothelial-large_vessel_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.18e-07	191	54	6	b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.22e-07	192	54	6	285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.22e-07	192	54	6	56b021c297a21dff357531f21e2464f85186106d
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.25e-07	193	54	6	58c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.50e-07	199	54	6	a3ec743b978ba8fdf1677b4971b5731f50ddd30f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 GJA4 ADCY4 VWF PECAM1 PLXND1	1.55e-07	200	54	6	93e13937ec74418a697c37d56f57509fb2154780
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PCSK5 GJA4 PGA4 ADCY4 VWF PECAM1	1.55e-07	200	54	6	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PCSK5 GJA4 PGA4 ADCY4 VWF PECAM1	1.55e-07	200	54	6	ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell	COVID-19-kidney-Epithelial_(EC)\|kidney / Disease (COVID-19 only), tissue and cell type	ADCY4 GJD2 VWF PECAM1 PLXND1	1.47e-06	160	54	5	0d4880f85565d8c540c94a8f8109147b3029279a
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 GJA4 ADCY4 VWF PECAM1	2.15e-06	173	54	5	b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 VWF PECAM1 PLXND1	2.15e-06	173	54	5	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCSK5 GJA4 ADCY4 VWF PECAM1	2.15e-06	173	54	5	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	facs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 ADCY4 VWF PECAM1 PLXND1	2.22e-06	174	54	5	40bb87d219aafab0357ab0d797efd38085fc0312
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN2B BRINP2 ASB2 LRP1B PRDM6	2.28e-06	175	54	5	d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCell	facs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCN2B BRINP2 ASB2 LRP1B PRDM6	2.28e-06	175	54	5	cf15465855602ba135752c18755e3e058dbd42ec
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 ADCY4 VWF GPAM ASB2	2.34e-06	176	54	5	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 ADCY4 VWF GPAM ASB2	2.34e-06	176	54	5	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 VWF PECAM1 PLXND1	2.34e-06	176	54	5	27e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 GJA4 VWF PECAM1 PLXND1	2.34e-06	176	54	5	d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PCSK5 GJA4 ADCY4 VWF PECAM1	2.41e-06	177	54	5	5ff8dcfb030312126695d53a026d2e104a401b83
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAM170B GJA4 ADCY4 VWF PECAM1	2.41e-06	177	54	5	12f8627124acbf436e75681ff1ce429ff5e3f256
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-capillary_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAM170B GJA4 ADCY4 VWF PECAM1	2.41e-06	177	54	5	fdf2af00fc971f0cd3915e1416e4a256458d6ea8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 ADCY4 VWF PECAM1 PLXND1	2.48e-06	178	54	5	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SCN2B BRINP2 ASB2 ADCY5	2.55e-06	179	54	5	8da6863edc756540bb097cc7221c1408640d9bb4
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SCN2B BRINP2 ASB2 ADCY5	2.55e-06	179	54	5	f39c13c99a07d009cc677e363ffe089089c64916
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GJA4 ADCY4 VWF PECAM1 PLXND1	2.62e-06	180	54	5	5861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	2.69e-06	181	54	5	9bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	2.76e-06	182	54	5	0639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 GJA4 VWF PECAM1 PLXND1	2.76e-06	182	54	5	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l19\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJA4 ADCY4 VWF PECAM1 PLXND1	2.76e-06	182	54	5	840427d1c23d60482c943ff006b14007ed44d247
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 GJA4 VWF PECAM1 PLXND1	2.76e-06	182	54	5	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	2.76e-06	182	54	5	0346f81bbb1f309f3e9d063b20547d548d09472c
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SCN2B BRINP2 ASB2 ADCY5	2.84e-06	183	54	5	8d45dff06a199b1369576657f7f9dc0249c5f841
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-Late_cap\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GJA4 ADCY4 VWF PECAM1 PLXND1	2.84e-06	183	54	5	3e69cc605f166a1f04e3d077935f7cfd806f1ffd
ToppCell	facs-Heart-LA-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 SCN2B BRINP2 ASB2 ADCY5	2.84e-06	183	54	5	421265fa15d5a028cb567bb0904e670473ef102b
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GJA4 ADCY4 VWF PECAM1 PLXND1	2.84e-06	183	54	5	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	Mesenchymal_cells-Smooth_muscle\|Mesenchymal_cells / Lineage and Cell class	GJA4 SCN2B BRINP2 ASB2 ADCY5	2.91e-06	184	54	5	83987abaedc26e6da477bc70d65e10b1ab1aea60
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	PCSK5 ADCY4 VWF PECAM1 PLXND1	2.91e-06	184	54	5	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	2.91e-06	184	54	5	df2d42e1eae29fa0a1ed9e389c95b38952b46892
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	2.91e-06	184	54	5	1ace70f12b417185bdd46042833f72b3b6815966
ToppCell	facs-Bladder-nan-18m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 VWF PECAM1 ASB2 ADCY5	2.99e-06	185	54	5	3e00879466e626aa8604efecfc4678d64f54dbfc
ToppCell	droplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 GJA4 ADCY4 VWF PECAM1	2.99e-06	185	54	5	eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	2.99e-06	185	54	5	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	facs-Bladder-nan-18m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 VWF PECAM1 ASB2 ADCY5	2.99e-06	185	54	5	3dc5812c961ff209f197ff4cbfb90009c0537550
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 ADCY4 VWF PECAM1 LRP1B	3.07e-06	186	54	5	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.07e-06	186	54	5	9d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 GJA4 ADCY4 VWF PECAM1	3.07e-06	186	54	5	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADCY4 VWF PECAM1 PLXND1	3.07e-06	186	54	5	5302399825f213d105ac70b91366a4513b732838
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 VWF CDH20 PECAM1 PLXND1	3.07e-06	186	54	5	055cc23c4db9aad2d6c62e62c8e58bfe5047c6b1
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.15e-06	187	54	5	0ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ADCY4 VWF PECAM1 PLXND1 TECTA	3.15e-06	187	54	5	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 GJA4 ADCY4 VWF PECAM1	3.15e-06	187	54	5	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.15e-06	187	54	5	25efb82afe863a853ecdd781ad89026c993aaa67
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 GJA4 VWF PECAM1 PLXND1	3.15e-06	187	54	5	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	GJA4 ADCY4 VWF PECAM1 PLXND1	3.15e-06	187	54	5	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 GJA4 ADCY4 VWF PECAM1	3.15e-06	187	54	5	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	droplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 GJA4 ADCY4 VWF PECAM1	3.24e-06	188	54	5	405efea75233ecf70f7d19b630230798d817b7f2
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-arterial_capillary\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 VWF PECAM1 OR52N5 PLXND1	3.24e-06	188	54	5	a11b12f1857953bcdbfb5f25e127f2350c39567d
ToppCell	P28-Endothelial-large_vessel_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 ADCY4 VWF PECAM1 PLXND1	3.24e-06	188	54	5	263169029293e005bcffd87db20221fdd2d3917e
ToppCell	PCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GJA4 ADCY4 VWF PECAM1 SLC22A24	3.24e-06	188	54	5	b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.32e-06	189	54	5	db09d591b885ce2bc9e353f08b6694e2192582e1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 GJA4 ADCY4 VWF PECAM1	3.32e-06	189	54	5	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 GJA4 ADCY4 VWF PECAM1	3.32e-06	189	54	5	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.32e-06	189	54	5	9e58411e51019ca59e78d3e737d65d2bcbbea2be
ToppCell	E17.5-Endothelial-large_vessel_endothelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PCSK5 GJA4 ADCY4 VWF PECAM1	3.32e-06	189	54	5	360f09f46231a83f99d8fa0158b72a38068e1642
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.32e-06	189	54	5	a34f008dfcee4012977bbc5b60de6f0329ca2f65
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GJA4 ADCY4 VWF PECAM1 PLXND1	3.41e-06	190	54	5	9a2244c3973aee7270646bf00db7727edb9decc5
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.41e-06	190	54	5	32400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.41e-06	190	54	5	92fdfed12061ee9f6c7171cf8a7f3344921f2d40
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PCSK5 GJA4 ADCY4 VWF PECAM1	3.49e-06	191	54	5	0b022d8b39eac36115b269aac11a5eaa492754cc
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 GJA4 ADCY4 VWF PECAM1	3.49e-06	191	54	5	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	Endothelial-C\|World / shred on cell class and cell subclass (v4)	PCSK5 GJA4 ADCY4 VWF PECAM1	3.49e-06	191	54	5	bf203931f973098b79ec681d1dd0854419819e98
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.59e-06	192	54	5	1f35efb0765e05f7f9c881849953bef3965be25a
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJA4 ADCY4 VWF PECAM1 PLXND1	3.59e-06	192	54	5	5a0615fdc217554ccd611504b16e5d97628e207d
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADCY4 VWF PECAM1 PLXND1	3.68e-06	193	54	5	88cd7d0d0da5c776b49fc131f746fe5ad9676fb7
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADCY4 VWF PECAM1 PLXND1	3.68e-06	193	54	5	3a5090f81f35026f435f4a250d1e77601a53af15
ToppCell	PCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	GJA4 ADCY4 VWF PECAM1 SLC22A24	3.68e-06	193	54	5	72d20ee257149b238016b44d183ce3fc24b8f621
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GJA4 ADCY4 VWF PECAM1 PLXND1	3.68e-06	193	54	5	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating3_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GJA4 ADCY4 VWF PECAM1 PLXND1	3.68e-06	193	54	5	f7e4a390921780587b9bd084e495e646fa1ec74f
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJA4 ADCY4 VWF PECAM1 PLXND1	3.68e-06	193	54	5	13731b7fc1e3bec0cebc44bad7e2ecea358bb76a
Drug	heptanol	ERVK-6 GJA4 GJD2 CDH20	2.96e-06	42	54	4	CID000008129
Drug	NSC-4928	ADCY4 VWF PAPPA ADCY5	1.09e-05	58	54	4	CID000221086
Drug	reproterol	ERVK-6 ADCY4 ADCY5	1.63e-05	21	54	3	CID000025654
Drug	benzilate	ADCY4 TAAR5 TECTA ADCY5	1.83e-05	66	54	4	CID000201538
Drug	NAIN	ERVK-6 ADCY4 ADCY5	2.46e-05	24	54	3	CID000195228
Drug	U3 66	VWF PECAM1 KMT2A	3.15e-05	26	54	3	CID000026062
Disease	response to radiation, prostate carcinoma, erectile dysfunction	DCAF8L1 FSHR LRP1B	4.07e-05	37	53	3	EFO_0001663, EFO_0004234, GO_0009314
Disease	transient cerebral ischemia (implicated_via_orthology)	VWF KMT2A PLXND1	2.11e-04	64	53	3	DOID:224 (implicated_via_orthology)
Disease	Proteinuria	VWF LRP2	3.27e-04	15	53	2	HP_0000093
Disease	3-hydroxypropylmercapturic acid measurement	VWF KMT2A PAPPA GPAM LRP1B	4.21e-04	352	53	5	EFO_0007014
Disease	migraine disorder, Headache	PAPPA REST CHRM4	5.04e-04	86	53	3	HP_0002315, MONDO_0005277
Disease	carotid artery disease (is_marker_for)	VWF PAPPA	5.31e-04	19	53	2	DOID:3407 (is_marker_for)
Disease	hemoglobin change measurement	PPP2R2A KMT2A	7.15e-04	22	53	2	EFO_0600027
Disease	myocardial infarction (is_implicated_in)	GJA4 PECAM1 PAPPA	7.60e-04	99	53	3	DOID:5844 (is_implicated_in)
Disease	CFTR mutation carrier status	PCSK5 GPAM	9.25e-04	25	53	2	EFO_0021794
Disease	Autosomal dominant nonsyndromic hearing loss	REST TECTA	1.25e-03	29	53	2	cv:C5779548
Disease	cardiovascular age measurement	SIPA1L1 ZC3H3	1.25e-03	29	53	2	EFO_0803380
Disease	acylcarnitine measurement	PPP2R2A GPAM TM2D1	1.56e-03	127	53	3	EFO_0005059
Disease	Heart Failure, Diastolic	SIPA1L1 PLXND1	1.61e-03	33	53	2	C1135196
Disease	pack-years measurement, systolic blood pressure	LRP2 LRP1B	1.71e-03	34	53	2	EFO_0006335, EFO_0006526

Protein segments in the cluster

Peptide	Gene	Start	Entry
STINPACYALCNATF	CHRM4	446	P08173
AEPNSFHVCITSYTQ	EP400	1186	Q96L91
FYHNCSGQTQSCPSA	ERVK-19	271	O71037
FYHNCSGQTQSCPSA	ERVK-8	271	Q902F8
VCTPSLCFITYSVHQ	GJD2	86	Q9UKL4
AAEFHPNSCNTFVYS	PPP2R2A	231	P63151
ATASACTNRQPAHFY	ASB2	51	Q96Q27
HQSYECVCVLFASVP	ADCY4	866	Q8NFM4
FSCTNIVGVCTHYPA	ADCY5	386	O95622
PACCITFVVYENVSH	SLC25A32	291	Q9H2D1
YCSSLACTNHNRFNP	PGA5	106	P0DJD9
NCSFYGHPETNNFCS	OTUD7B	806	Q6GQQ9
QACNYEETFPHICAA	MUC6	621	Q6W4X9
PFKCDQCSYVASNQH	REST	331	Q13127
HTCACPTNFYLAADN	LRP1B	3296	Q9NZR2
HSLCYNDCTFSRNTP	ELAPOR1	651	Q6UXG2
CANVCYDVFSPVSHL	GJD4	61	Q96KN9
SHYPAANPSVIVCCS	CSRNP3	491	Q8WYN3
YFLNEETNSCVTHCP	PCSK5	711	Q92824
DCSRTAQVYPHTACT	PLXND1	701	Q9Y4D7
AQVYPHTACTSCLSA	PLXND1	706	Q9Y4D7
YCTAFNRANHASSVP	PECAM1	571	P16284
TSPAASICTCHNNFY	EPHB3	311	P54753
FNTVDCAPESYVQCH	MED25	71	Q71SY5
PASCLDTQYTCDNHQ	LRP2	1106	P98164
ETYSPAEQSCVHFAC	PAPPA	1196	Q13219
FYHNCSGQTQSCPSA	ERVK-7	1031	P63135
AAPQSVCAFYTHVQT	FAM170B	101	A6NMN3
YCSSLACTNHNRFNP	PGA3	106	P0DJD8
YQCGHCSQSFSQPSE	PRDM6	501	Q9NQX0
SHTRTTYQQNFCCPS	C3orf84	136	H3BNL1
FYHNCSGQTQSCPSA	ERVK-25	271	P61570
FYHNCSGQTQSCPSA	ERVK-6	271	Q69384
YVPQTCAVNSTVHSY	CDH20	711	Q9HBT6
TAHTCFNQLCLPTYD	AREL1	786	O15033
QICICSQFSVPSSYH	ERAP2	31	Q6P179
AARFINHSCEPNCYS	KMT2A	3901	Q03164
YCDFPTNITCVVYSH	DCAF8L1	386	A6NGE4
FYHNCSGQTQSCPSA	HERVK_113	271	Q902F9
CTNVCYDQAFPISHI	GJA4	61	P35212
SVCWQQHCASPAFAY	FBXL5	531	Q9UKA1
EASLTYPSHCCAFAN	FSHR	266	P23945
SNPTICFVYDQTHSN	ERVFC1	81	P60507
PFCQSNIISHTYCDH	OR52N5	176	Q8NH56
YCSSLACTNHNRFNP	PGA4	106	P0DJD7
CQVYAFPVSVCLAHS	RXFP3	366	Q9NSD7
TVYCNNSFPIHSSNS	TAS2R39	181	P59534
FCYQVNGSCPRTVHT	TAAR5	16	O14804
SHQTIPSVYINNICC	GFM2	11	Q969S9
SNTCAAFAPTFLVYC	SLC22A24	186	Q8N4F4
TISLPCQTFYQVCHE	GPAM	631	Q9HCL2
VHNPCSDSVCYSVAV	SIPA1L1	741	O43166
CVHVRCSFSYPVDSQ	SIGLEC7	41	Q9Y286
FLEQSHSCTCPYDQS	BRINP2	436	Q9C0B6
CVSTVQCPSFSHYSV	TECTA	591	O75443
ARLPCTFNSCYTVNH	SCN2B	46	O60939
CSPSYRQVNCFSHLS	TSSK4	181	Q6SA08
ICSNSNCPYSHVYVS	ZC3H3	736	Q8IXZ2
YTHTQCGTAFSYQPC	ZNF441	141	Q8N8Z8
PATFYAICQQDSCHQ	VWF	2156	P04275
HPSTVLSCNCEYNSF	nan	51	Q6ZSR6
VNCTNYTAHVSCFPA	TM2D1	71	Q9BX74
NYHTCFPNHTLNSAC	TTLL6	326	Q8N841
ACSQVYSFFHCADPS	PITPNM3	426	Q9BZ71