Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsuperoxide-generating NADPH oxidase activator activity

NCF1 NCF1C NCF1B

8.14e-0610833GO:0016176
GeneOntologyMolecularFunctionphosphatidylinositol-3,4-bisphosphate binding

NCF1 OBSCN NCF1C NCF1B

1.32e-0535834GO:0043325
GeneOntologyMolecularFunctionsuperoxide-generating NAD(P)H oxidase activity

NCF1 NCF1C NCF1B

1.48e-0512833GO:0016175
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

NCF1 NCF1C NCF1B

7.50e-0520833GO:0050664
GeneOntologyMolecularFunctionprotein serine kinase activity

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

1.33e-04363838GO:0106310
GeneOntologyMolecularFunctionN-acetyltransferase activity

BRPF3 NAA80 SATL1 EP300

3.13e-0478834GO:0008080
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

5.31e-04446838GO:0004674
GeneOntologyMolecularFunctionprotein kinase activity

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 NRG2 MAP4K4 WNK2

8.55e-04600839GO:0004672
GeneOntologyMolecularFunctionN-acyltransferase activity

BRPF3 NAA80 SATL1 EP300

8.66e-04102834GO:0016410
GeneOntologyMolecularFunctionacetyltransferase activity

BRPF3 NAA80 SATL1 EP300

9.31e-04104834GO:0016407
GeneOntologyMolecularFunctionbeta-catenin binding

TJP1 APC2 MED12L EP300

1.58e-03120834GO:0008013
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

BRPF3 EP300

1.73e-0315832GO:0010484
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

BRPF3 NAA80 EP300

2.00e-0360833GO:0034212
GeneOntologyBiologicalProcessneutrophil-mediated killing of gram-positive bacterium

NCF1 NCF1C NCF1B

6.25e-075833GO:0070946
GeneOntologyBiologicalProcessNADP catabolic process

NCF1 NCF1C NCF1B

2.17e-067833GO:0006742
GeneOntologyBiologicalProcessneutrophil-mediated killing of fungus

NCF1 NCF1C NCF1B

2.17e-067833GO:0070947
GeneOntologyBiologicalProcessregulation of respiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

1.01e-0511833GO:0060264
GeneOntologyBiologicalProcessrespiratory burst involved in inflammatory response

NCF1 NCF1C NCF1B

1.75e-0513833GO:0002536
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

RAF1 WASL EPS8L2 LATS1 G3BP1 ABI3BP TJP1 CPEB3 SLITRK5 NEK7 AUTS2 NRG2 CTTN MAP4K4 EP300 ARHGAP33

1.79e-0511898316GO:0044087
GeneOntologyBiologicalProcessneutrophil-mediated killing of bacterium

NCF1 NCF1C NCF1B

3.39e-0516833GO:0070944
GeneOntologyBiologicalProcessresponse to yeast

NCF1 NCF1C NCF1B

4.91e-0518833GO:0001878
GeneOntologyBiologicalProcessneutrophil-mediated killing of symbiont cell

NCF1 NCF1C NCF1B

5.81e-0519833GO:0070943
GeneOntologyBiologicalProcessrespiratory burst involved in defense response

NCF1 NCF1C NCF1B

6.82e-0520833GO:0002679
GeneOntologyBiologicalProcessneutrophil mediated cytotoxicity

NCF1 NCF1C NCF1B

7.93e-0521833GO:0070942
GeneOntologyBiologicalProcessnegative regulation of smooth muscle contraction

NCF1 NCF1C NCF1B

9.16e-0522833GO:0045986
GeneOntologyBiologicalProcesshydrogen peroxide biosynthetic process

NCF1 NCF1C NCF1B

9.16e-0522833GO:0050665
GeneOntologyBiologicalProcessregulation of respiratory burst

NCF1 NCF1C NCF1B

1.05e-0423833GO:0060263
GeneOntologyBiologicalProcessbiological process involved in interaction with symbiont

HMGA2 NCF1 NCF1C NCF1B EP300

2.15e-04135835GO:0051702
GeneOntologyBiologicalProcessregulation of cell junction assembly

ABI3BP TJP1 CPEB3 SLITRK5 NRG2 MAP4K4 ARHGAP33

2.48e-04309837GO:1901888
GeneOntologyBiologicalProcessregulation of smooth muscle contraction

NCF1 CTTN NCF1C NCF1B

2.91e-0479834GO:0006940
GeneOntologyBiologicalProcesssmall GTPase-mediated signal transduction

RAF1 EPS8L2 LZTR1 G3BP1 ARHGAP10 OBSCN AUTS2 MAP4K4 ARHGAP33

3.10e-04538839GO:0007264
GeneOntologyBiologicalProcessactin cytoskeleton organization

WASL MAGEL2 LATS1 ABI3BP MICALL2 TJP1 OBSCN AUTS2 NAA80 CTTN EP300

3.64e-048038311GO:0030036
GeneOntologyBiologicalProcessnegative regulation of muscle contraction

NCF1 NCF1C NCF1B

3.75e-0435833GO:0045932
GeneOntologyBiologicalProcessregulation of small GTPase mediated signal transduction

RAF1 EPS8L2 LZTR1 ARHGAP10 OBSCN AUTS2 MAP4K4

3.90e-04333837GO:0051056
GeneOntologyBiologicalProcesscell junction assembly

ABI3BP MICALL2 TJP1 CPEB3 SLITRK5 NRG2 CTTN MAP4K4 ARHGAP33

4.65e-04569839GO:0034329
GeneOntologyBiologicalProcesskilling by host of symbiont cells

NCF1 NCF1C NCF1B

4.79e-0438833GO:0051873
GeneOntologyBiologicalProcessleukotriene metabolic process

NCF1 NCF1C NCF1B

6.00e-0441833GO:0006691
GeneOntologyCellularComponentNADPH oxidase complex

NCF1 NCF1C NCF1B

4.55e-0518823GO:0043020
HumanPhenoDeviation of finger

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 COG1 NCF1 AUTS2 EP300 PHF21A

1.12e-055372411HP:0004097
HumanPhenoMitral valve prolapse

RAF1 ZNF469 LZTR1 FBN2 NCF1 EP300

1.65e-05123246HP:0001634
HumanPhenoDeviation of the hand or of fingers of the hand

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 COG1 NCF1 AUTS2 EP300 PHF21A

1.80e-055642411HP:0009484
HumanPhenoDownslanted palpebral fissures

RAF1 LZTR1 SATB1 TCOF1 COG1 APC2 MED12L AUTS2 ZMIZ1 EP300

3.97e-054972410HP:0000494
HumanPhenoAbnormal mitral valve morphology

RAF1 ZNF469 LZTR1 FBN2 NCF1 EP300

4.39e-05146246HP:0031477
HumanPhenoAbnormal nasal bridge morphology

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

4.41e-0510292414HP:0000422
HumanPhenoShort attention span

MAGEL2 HMGA2 SATB1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

5.59e-055172410HP:0000736
HumanPhenoAbnormal curvature of the vertebral column

RAF1 ZNF469 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 COG1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300

6.23e-0512192415HP:0010674
HumanPhenoReduced attention regulation

MAGEL2 HMGA2 SATB1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

6.49e-055262410HP:5200044
HumanPhenoAbnormality of mouth size

RAF1 LZTR1 TCOF1 COG1 NCF1 MED12L AUTS2 ZMIZ1 EP300

7.56e-05425249HP:0011337
HumanPhenoAbnormal hand morphology

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 COG1 NCF1 APC2 AUTS2 ZMIZ1 EP300 PHF21A

7.94e-0510822414HP:0005922
HumanPhenoHyperactivity

MAGEL2 HMGA2 TCF20 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

1.08e-045582410HP:0000752
HumanPhenoRadial deviation of finger

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 NCF1 AUTS2 EP300 PHF21A

1.14e-04448249HP:0009466
HumanPhenoBrachycephaly

RAF1 FBN2 TCF20 SATB1 TCOF1 AUTS2 PHF21A

1.15e-04253247HP:0000248
HumanPhenoAbnormal mandible morphology

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 CDC73 ZMIZ1 EP300 PHF21A

1.16e-0411182414HP:0000277
HumanPhenoScoliosis

RAF1 ZNF469 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 COG1 NCF1 APC2 AUTS2 ZMIZ1 EP300

1.21e-0411222414HP:0002650
HumanPhenoRadial deviation of the hand or of fingers of the hand

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 NCF1 AUTS2 EP300 PHF21A

1.31e-04456249HP:0009485
HumanPhenoAbnormality of calvarial morphology

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 TCOF1 NCF1 APC2 MED12L AUTS2 EP300 PHF21A

1.37e-0411342414HP:0002648
HumanPhenoFeeding difficulties

RAF1 MAGEL2 LZTR1 HMGA2 SATB1 TCOF1 COG1 OBSCN MED12L AUTS2 CDC73 ZMIZ1 EP300

1.41e-049822413HP:0002022
HumanPhenoAbnormal penis morphology

RAF1 MAGEL2 HMGA2 TCOF1 COG1 NCF1 APC2 MED12L ZMIZ1 EP300 PHF21A

1.62e-047122411HP:0000036
HumanPhenoConstipation

MAGEL2 TCF20 SATB1 NCF1 APC2 MED12L CDC73 ZMIZ1 EP300

1.72e-04472249HP:0002019
HumanPhenoAbnormal male external genitalia morphology

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 COX11 CDC73 ZMIZ1 EP300 PHF21A

1.81e-0413292415HP:0000032
HumanPhenoFeeding difficulties in infancy

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 MED12L AUTS2 ZMIZ1 EP300

1.84e-045942410HP:0008872
HumanPhenoAbnormality of the jaws

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 CDC73 ZMIZ1 EP300 PHF21A

2.05e-0411752414HP:0000209
HumanPhenoAbnormal jaw morphology

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 CDC73 ZMIZ1 EP300 PHF21A

2.07e-0411762414HP:0030791
HumanPhenoFrontal bossing

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 TCOF1 NCF1 MED12L EP300

2.25e-047382411HP:0002007
HumanPhenoSlanting of the palpebral fissure

RAF1 MAGEL2 LZTR1 SATB1 TCOF1 COG1 APC2 MED12L AUTS2 ZMIZ1 EP300

2.28e-047392411HP:0200006
HumanPhenoAbnormality of the palpebral fissures

RAF1 MAGEL2 LZTR1 SATB1 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300

2.32e-048802412HP:0008050
HumanPhenoAbnormal shape of the frontal region

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 TCOF1 NCF1 MED12L EP300

2.33e-047412411HP:0011218
HumanPhenoPatent ductus arteriosus

RAF1 LZTR1 FBN2 TCOF1 NCF1 APC2 ZMIZ1 EP300

2.34e-04382248HP:0001643
HumanPhenoAbnormal frontal bone morphology

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 TCOF1 NCF1 MED12L EP300

2.36e-047422411HP:0430000
HumanPhenoReduced impulse control

CD3E MAGEL2 HMGA2 TCF20 SATB1 NCF1 APC2 MED12L AUTS2 CDC73 ZMIZ1 EP300 PHF21A

2.39e-0410322413HP:5200045
HumanPhenoAbnormal external genitalia

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 COX11 CDC73 ZMIZ1 EP300 PHF21A

2.67e-0413722415HP:0000811
HumanPhenoMidface retrusion

RAF1 LZTR1 TCF20 SATB1 TCOF1 COG1 ZMIZ1

2.75e-04291247HP:0011800
HumanPhenoAbnormal finger morphology

RAF1 ZNF469 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 COG1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

2.99e-0413852415HP:0001167
HumanPhenoWide nasal bridge

RAF1 LZTR1 TCOF1 COG1 NCF1 APC2 AUTS2 ZMIZ1 EP300

3.02e-04508249HP:0000431
HumanPhenoNeoplasm of the ear

LZTR1 COG1 APC2

3.10e-0429243HP:0012780
HumanPhenoAbnormal eyelid morphology

RAF1 ZNF469 MAGEL2 LZTR1 TCF20 SATB1 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

3.64e-0414082415HP:0000492
HumanPhenoCryptorchidism

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 ZMIZ1 EP300

3.71e-047802411HP:0000028
HumanPhenoLong fingers

ZNF469 MAGEL2 FBN2 TCF20 MED12L ZMIZ1 PHF21A

3.75e-04306247HP:0100807
HumanPhenoPulmonic stenosis

RAF1 ZNF469 LZTR1 NCF1 EP300

3.81e-04138245HP:0001642
HumanPhenoAttention deficit hyperactivity disorder

MAGEL2 HMGA2 NCF1 APC2 MED12L AUTS2 ZMIZ1 PHF21A

4.01e-04413248HP:0007018
HumanPhenoAbnormal lip morphology

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 SATB1 TCOF1 COG1 NCF1 MED12L AUTS2 ZMIZ1 EP300 PHF21A

4.08e-0412492414HP:0000159
HumanPhenoMacrostomia

RAF1 LZTR1 TCOF1 NCF1 AUTS2 ZMIZ1

4.24e-04220246HP:0000181
HumanPhenoWide mouth

RAF1 LZTR1 TCOF1 NCF1 AUTS2 ZMIZ1

4.24e-04220246HP:0000154
HumanPhenoAbnormal calvaria morphology

RAF1 MAGEL2 LZTR1 FBN2 HMGA2 TCF20 SATB1 TCOF1 NCF1 APC2 MED12L AUTS2 EP300 PHF21A

4.27e-0412542414HP:0002683
HumanPhenoClinodactyly of the 5th finger

RAF1 LZTR1 HMGA2 TCF20 NCF1 AUTS2 EP300 PHF21A

4.50e-04420248HP:0004209
HumanPhenoClinodactyly of hands

RAF1 LZTR1 HMGA2 TCF20 NCF1 AUTS2 EP300 PHF21A

4.58e-04421248HP:0001157
HumanPhenoDeviation of the 5th finger

RAF1 LZTR1 HMGA2 TCF20 NCF1 AUTS2 EP300 PHF21A

4.58e-04421248HP:0009179
HumanPhenoAbnormal location of ears

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 SATB1 TCOF1 COG1 NCF1 AUTS2 ZMIZ1 EP300

4.64e-049452412HP:0000357
HumanPhenoAbnormality of the male genitalia

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 COX11 CDC73 ZMIZ1 EP300 PHF21A

4.64e-0414372415HP:0010461
HumanPhenoOsteopenia

RAF1 MAGEL2 LZTR1 FBN2 COG1 NCF1 CDC73

5.03e-04321247HP:0000938
HumanPhenoAbnormal atrial septum morphology

RAF1 MAGEL2 LZTR1 FBN2 COG1 NCF1 APC2 AUTS2 EP300

5.06e-04544249HP:0011994
HumanPhenoPectus excavatum

RAF1 LZTR1 FBN2 NCF1 APC2 ZMIZ1 EP300

5.22e-04323247HP:0000767
HumanPhenoAutistic behavior

MAGEL2 TCF20 SATB1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

5.51e-046782410HP:0000729
HumanPhenoCongenital abnormal hair pattern

RAF1 MAGEL2 LZTR1 SATB1 TCOF1 APC2 EP300

5.62e-04327247HP:0011361
HumanPhenoUterine leiomyoma

LZTR1 CDC73

5.86e-048242HP:0000131
HumanPhenoNarrow mouth

TCOF1 COG1 MED12L AUTS2 ZMIZ1 EP300

5.90e-04234246HP:0000160
HumanPhenoAbnormality of bone mineral density

RAF1 ZNF469 MAGEL2 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 CDC73 PHF21A

5.92e-048222411HP:0004348
HumanPhenoAbnormal testis morphology

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 COX11 CDC73 ZMIZ1 EP300

6.10e-0411292413HP:0000035
HumanPhenoAbnormal bone ossification

RAF1 ZNF469 MAGEL2 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 CDC73 PHF21A

6.25e-048272411HP:0011849
HumanPhenoNon-obstructive azoospermia

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 COX11 CDC73 ZMIZ1 EP300

6.27e-0411322413HP:0011961
HumanPhenoThick eyebrow

MAGEL2 HMGA2 SATB1 AUTS2 EP300

6.31e-04154245HP:0000574
HumanPhenoAuditory sensitivity

NCF1 AUTS2 EP300

6.43e-0437243HP:0025112
HumanPhenoAbnormal upper lip morphology

MAGEL2 LZTR1 TCF20 SATB1 TCOF1 COG1 NCF1 MED12L AUTS2 ZMIZ1 EP300 PHF21A

6.58e-049802412HP:0000177
HumanPhenoDeviation of the hallux

ZNF469 NCF1 ZMIZ1 EP300

6.79e-0488244HP:0010051
HumanPhenoCompulsive behaviors

MAGEL2 TCF20 NCF1 AUTS2 EP300

7.10e-04158245HP:0000722
HumanPhenoMicrognathia

RAF1 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 AUTS2 ZMIZ1 EP300 PHF21A

7.40e-048432411HP:0000347
HumanPhenoFinger clinodactyly

RAF1 LZTR1 HMGA2 TCF20 NCF1 AUTS2 EP300 PHF21A

7.40e-04452248HP:0040019
HumanPhenoAbnormal midface morphology

RAF1 LZTR1 TCF20 SATB1 TCOF1 COG1 NCF1 AUTS2 ZMIZ1 EP300

7.49e-047042410HP:0000309
HumanPhenoPalmoplantar cutis laxa

ZNF469 LZTR1

7.51e-049242HP:0007517
HumanPhenoPoor coordination

TCF20 APC2 EP300

7.52e-0439243HP:0002370
HumanPhenoClinodactyly

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 NCF1 AUTS2 EP300 PHF21A

7.55e-04574249HP:0030084
HumanPhenoAplasia/Hypoplasia of the mandible

RAF1 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 AUTS2 ZMIZ1 EP300 PHF21A

7.55e-048452411HP:0009118
HumanPhenoAzoospermia

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 COX11 CDC73 ZMIZ1 EP300

7.83e-0411572413HP:0000027
HumanPhenoAbnormality of refraction

ZNF469 MAGEL2 FBN2 TCF20 SATB1 NCF1 APC2 MED12L ZMIZ1 EP300

7.93e-047092410HP:0000539
HumanPhenoStrabismus

RAF1 MAGEL2 LZTR1 TCF20 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

7.97e-0411592413HP:0000486
HumanPhenoAbnormal pulmonary valve physiology

RAF1 ZNF469 LZTR1 NCF1 EP300

8.18e-04163245HP:0031654
HumanPhenoFeeding difficulties

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 TCOF1 COG1 APC2 MED12L AUTS2 COX11 ZMIZ1 EP300

8.62e-0411682413HP:0011968
HumanPhenoAbnormality of the urethra

RAF1 HMGA2 COG1 NCF1 APC2 MED12L ZMIZ1 EP300

8.95e-04465248HP:0000795
HumanPhenoAbnormality of the philtrum

MAGEL2 LZTR1 SATB1 COG1 NCF1 MED12L AUTS2 ZMIZ1 EP300 PHF21A

9.59e-047262410HP:0000288
HumanPhenoPosteriorly rotated ears

RAF1 LZTR1 TCF20 SATB1 TCOF1 COG1 NCF1 EP300

9.61e-04470248HP:0000358
HumanPhenoAbnormally increased volition

MAGEL2 HMGA2 TCF20 SATB1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

9.65e-048692411HP:5200263
HumanPhenoAbnormal mitral valve morphology

RAF1 ZNF469 LZTR1 FBN2 NCF1 EP300

9.70e-04257246HP:0001633
HumanPhenoExcessive wrinkled skin

RAF1 ZNF469 LZTR1

1.00e-0343243HP:0007392
HumanPhenoAbnormal spermatogenesis

RAF1 MAGEL2 LZTR1 HMGA2 TCOF1 COG1 NCF1 APC2 AUTS2 COX11 CDC73 ZMIZ1 EP300

1.04e-0311902413HP:0008669
HumanPhenoAbnormal bone structure

RAF1 ZNF469 MAGEL2 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 CDC73 PHF21A

1.09e-038812411HP:0003330
HumanPhenoIntellectual disability, mild

RAF1 MAGEL2 HMGA2 TCF20 COG1 APC2 EP300

1.09e-03365247HP:0001256
HumanPhenoAbnormal conjugate eye movement

RAF1 MAGEL2 LZTR1 TCF20 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

1.11e-0311982413HP:0000549
HumanPhenoDiagnostic behavioral phenotype

MAGEL2 TCF20 SATB1 NCF1 APC2 MED12L AUTS2 ZMIZ1 EP300 PHF21A

1.20e-037472410HP:0025783
HumanPhenoProminent fingertip pads

LZTR1 MED12L EP300

1.22e-0346243HP:0001212
HumanPhenoEpicanthus

RAF1 ZNF469 LZTR1 TCF20 NCF1 AUTS2 ZMIZ1 EP300 PHF21A

1.24e-03614249HP:0000286
HumanPhenoHypospadias

RAF1 HMGA2 COG1 APC2 MED12L ZMIZ1 EP300

1.32e-03377247HP:0000047
HumanPhenoDownturned corners of mouth

MAGEL2 HMGA2 TCF20 MED12L PHF21A

1.35e-03182245HP:0002714
HumanPhenoAbnormal facial shape

RAF1 MAGEL2 LZTR1 HMGA2 TCF20 TCOF1 COG1 NCF1 APC2 MED12L AUTS2 EP300 PHF21A

1.35e-0312212413HP:0001999
HumanPhenoNeoplasm of the middle ear

COG1 APC2

1.36e-0312242HP:0100799
HumanPhenoCholesteatoma

COG1 APC2

1.36e-0312242HP:0009797
HumanPhenoAbnormality of the helix

RAF1 LZTR1 FBN2 ZMIZ1 EP300

1.38e-03183245HP:0000380
HumanPhenoProminent digit pad

LZTR1 MED12L EP300

1.38e-0348243HP:0011298
HumanPhenoAplasia/Hypoplasia involving bones of the skull

RAF1 LZTR1 FBN2 HMGA2 TCOF1 COG1 NCF1 AUTS2 ZMIZ1 EP300 PHF21A

1.51e-039152411HP:0009116
MousePhenoabnormal angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

1.34e-066583MP:0013254
MousePhenoincreased angiotensin I-converting enzyme activity

NCF1 NCF1C NCF1B

1.34e-066583MP:0003184
MousePhenoliver abscess

NCF1 NCF1C NCF1B

2.34e-067583MP:0003332
MousePhenoabnormal heart atrium morphology

RAF1 NCF1 AUTS2 ZMIZ1 NCF1C NCF1B EP300 NPAT

4.78e-06232588MP:0003105
MousePhenoimpaired granulocyte bactericidal activity

NCF1 NCF1C NCF1B

7.97e-0610583MP:0005074
MousePhenoimpaired cued conditioning behavior

EPS8L2 NCF1 AUTS2 NCF1C NCF1B

2.20e-0582585MP:0009456
MousePhenoabnormal cardiac muscle contractility

RAF1 LZTR1 ABI3BP NCF1 OBSCN NCF1C NCF1B EP300

3.24e-05302588MP:0002972
MousePhenoincreased heart atrium size

RAF1 NCF1 NCF1C NCF1B

3.82e-0546584MP:0008725
MousePhenoabnormal vascular endothelial cell physiology

NCF1 CTTN NCF1C NCF1B

4.17e-0547584MP:0004003
MousePhenoprenatal growth retardation

RAF1 CASC3 KLF8 WASL TCF20 G3BP1 TCOF1 TJP1 MIDEAS MAP4K4 INO80D EP300 NPAT

4.37e-058695813MP:0010865
MousePhenodecreased susceptibility to Orthomyxoviridae infection

NCF1 NCF1C NCF1B

5.29e-0518583MP:0020947
MousePhenoabnormal heart atrium size

RAF1 NCF1 NCF1C NCF1B

7.23e-0554584MP:0031576
MousePhenodecreased vasoconstriction

NCF1 NCF1C NCF1B

9.87e-0522583MP:0003026
MousePhenoincreased circulating renin level

NCF1 NCF1C NCF1B

1.13e-0423583MP:0003352
MousePhenoabnormal bile duct morphology

NCF1 AUTS2 NCF1C NCF1B

1.41e-0464584MP:0002928
MousePhenoabnormal anxiety-related response

FBN2 TCF20 CSF2RB ABI3BP NCF1 CPEB3 SLITRK5 AUTS2 CTTN NCF1C NCF1B

1.97e-047405811MP:0001362
MousePhenoimpaired muscle contractility

RAF1 LZTR1 ABI3BP NCF1 NCF1C NCF1B EP300

2.16e-04297587MP:0000738
MousePhenoabnormal circulating renin level

NCF1 NCF1C NCF1B

2.29e-0429583MP:0003349
MousePhenoabnormal muscle contractility

RAF1 LZTR1 ABI3BP NCF1 OBSCN NCF1C NCF1B EP300

3.09e-04418588MP:0005620
MousePhenoabnormal fear/anxiety-related behavior

FBN2 TCF20 CSF2RB PHF20L1 ABI3BP NCF1 CPEB3 SLITRK5 AUTS2 CTTN NCF1C NCF1B

3.24e-049195812MP:0002065
MousePhenodecreased cranium height

RAF1 LZTR1 HMGA2

3.39e-0433583MP:0008525
MousePhenoabnormal vascular development

RAF1 TJP1 NCF1 ZMIZ1 NCF1C NCF1B DCBLD2 EP300 NPAT

3.62e-04542589MP:0000259
MousePhenoimpaired smooth muscle contractility

NCF1 NCF1C NCF1B

4.04e-0435583MP:0000740
MousePhenogranulomatous inflammation

NCF1 NCF1C NCF1B

4.39e-0436583MP:0002500
MousePhenoabnormal cued conditioning behavior

EPS8L2 NCF1 AUTS2 NCF1C NCF1B

5.33e-04161585MP:0001454
MousePhenoskin lesions

NCF1 SLITRK5 NCF1C NCF1B

5.45e-0491584MP:0001212
MousePhenoimpaired conditioning behavior

EPS8L2 NCF1 AUTS2 NCF1C NCF1B

5.96e-04165585MP:0012317
MousePhenoabnormal response to cardiac infarction

ABI3BP NCF1 NCF1C NCF1B

6.16e-0494584MP:0000343
MousePhenoabnormal cell proliferation

RAF1 WASL LZTR1 LATS1 MAST4 SATB1 G3BP1 ABI3BP TCOF1 CPEB3 CDC73 ZMIZ1 DCBLD2 EP300

6.55e-0412945814MP:0000350
MousePhenoabnormal cranium size

RAF1 LZTR1 HMGA2 ZFHX4

6.94e-0497584MP:0010031
MousePhenoabnormal angiogenesis

TJP1 NCF1 ZMIZ1 NCF1C NCF1B DCBLD2 NPAT

8.35e-04372587MP:0000260
MousePhenodecreased cranium width

RAF1 HMGA2

9.08e-0411582MP:0008526
DomainZnF_C2HC

FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

2.65e-0955777SM00343
DomainZnf_CCHC

FAM90A14 FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

2.65e-0955777IPR001878
DomainSH3

EPS8L2 MYO15B TJP1 ARHGAP10 SH3D19 NCF1 OBSCN CTTN ARHGAP33

2.56e-07216779SM00326
DomainSH3

EPS8L2 MYO15B TJP1 ARHGAP10 SH3D19 NCF1 OBSCN CTTN ARHGAP33

2.56e-07216779PS50002
DomainSH3_domain

EPS8L2 MYO15B TJP1 ARHGAP10 SH3D19 NCF1 OBSCN CTTN ARHGAP33

2.99e-07220779IPR001452
DomainSH3_1

EPS8L2 ARHGAP10 SH3D19 NCF1 CTTN ARHGAP33

5.93e-05164776PF00018
DomainSer/Thr_kinase_AS

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

1.10e-04357778IPR008271
DomainS_TKc

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

1.14e-04359778SM00220
DomainPROTEIN_KINASE_ST

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

1.21e-04362778PS00108
DomainPkinase

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

1.72e-04381778PF00069
DomainSH3_9

ARHGAP10 SH3D19 CTTN ARHGAP33

3.02e-0478774PF14604
DomainZnf_FYVE_PHD

BRPF3 TCF20 PHF20L1 MOBP PHF21A

3.53e-04147775IPR011011
DomainSH3_2

MYO15B TJP1 SH3D19 ARHGAP33

4.39e-0486774IPR011511
DomainSH3_2

MYO15B TJP1 SH3D19 ARHGAP33

4.39e-0486774PF07653
DomainPROTEIN_KINASE_ATP

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

5.97e-04459778PS00107
DomainZF_PHD_1

BRPF3 TCF20 PHF20L1 PHF21A

6.66e-0496774PS01359
DomainProt_kinase_dom

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

9.02e-04489778IPR000719
DomainPROTEIN_KINASE_DOM

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

9.50e-04493778PS50011
DomainKinase-like_dom

RAF1 LATS1 MAST4 AAK1 OBSCN NEK7 MAP4K4 WNK2

1.73e-03542778IPR011009
DomainAT_hook

HMGA2 PHF21A

1.94e-0316772PF02178
DomainZinc_finger_PHD-type_CS

BRPF3 PHF20L1 PHF21A

2.45e-0365773IPR019786
DomainEPHD

BRPF3 TCF20

3.67e-0322772PS51805
DomainAcetyltransf_1

NAA80 SATL1

4.01e-0323772PF00583
DomainGNAT

NAA80 SATL1

4.73e-0325772PS51186
DomainGNAT_dom

NAA80 SATL1

4.73e-0325772IPR000182
DomainBromodomain_CS

BRPF3 EP300

5.11e-0326772IPR018359
DomainAT_hook

HMGA2 PHF21A

5.51e-0327772SM00384
DomainAT_hook_DNA-bd_motif

HMGA2 PHF21A

5.51e-0327772IPR017956
DomainLisH

TCOF1 NPAT

5.92e-0328772SM00667
DomainLisH

TCOF1 NPAT

5.92e-0328772IPR006594
DomainLISH

TCOF1 NPAT

5.92e-0328772PS50896
DomainPHD

BRPF3 TCF20 PHF21A

5.93e-0389773SM00249
DomainZnf_PHD

BRPF3 TCF20 PHF21A

6.31e-0391773IPR001965
DomainZF_PHD_2

BRPF3 TCF20 PHF21A

7.11e-0395773PS50016
DomainHMGI/Y_DNA-bd_CS

HMGA2 PHF21A

7.22e-0331772IPR000637
PathwayREACTOME_CROSS_PRESENTATION_OF_PARTICULATE_EXOGENOUS_ANTIGENS_PHAGOSOMES

NCF1 NCF1C NCF1B

5.18e-069573MM14524
PathwayBIOCARTA_FMLP_PATHWAY

RAF1 NCF1 NCF1C NCF1B

1.02e-0534574MM1399
PathwayREACTOME_RHO_GTPASES_ACTIVATE_NADPH_OXIDASES

NCF1 NCF1C NCF1B

1.35e-0425573MM15269
Pubmed

Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.

FAM90A14 FAM90A17 FAM90A19 FAM90A23 FAM90A2P FAM90A1 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

1.38e-2525871217684299
Pubmed

Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.

FAM90A14 FAM90A17 FAM90A19 FAM90A23 FAM90A2P FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10

6.26e-2123871018602769
Pubmed

Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.

FAM90A14 FAM90A17 FAM90A19 FAM90A26 FAM90A23 FAM90A1 FAM90A7 FAM90A9 FAM90A8 FAM90A10

1.21e-11164871022967998
Pubmed

Novel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium.

NCF1 CTTN NCF1C NCF1B

1.82e-10587422219181
Pubmed

A human MAP kinase interactome.

WASL LATS1 TCF20 ABI3BP SH3D19 SREBF2 EVPL MIDEAS MAP4K4 EP300 WNK2 ARHGAP33

3.33e-09486871220936779
Pubmed

Human transcription factor protein interaction networks.

KLF8 FBN2 TCF20 SATB1 GTF3C2 ZFHX4 G3BP1 RBM6 AUTS2 ZC3H18 ZMIZ1 CTTN MIDEAS INO80D EP300 PHF21A HOMEZ NPAT

1.30e-081429871835140242
Pubmed

Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia.

NCF1 NCF1C NCF1B

1.51e-08387318036262
Pubmed

Transient loss of resistance to pulmonary tuberculosis in p47(phox-/-) mice.

NCF1 NCF1C NCF1B

1.51e-08387310678931
Pubmed

Colitis susceptibility in p47(phox-/-) mice is mediated by the microbiome.

NCF1 NCF1C NCF1B

1.51e-08387327044504
Pubmed

Suppression of microglial inflammatory activity by myelin phagocytosis: role of p47-PHOX-mediated generation of reactive oxygen species.

NCF1 NCF1C NCF1B

1.51e-08387317167081
Pubmed

Mice lacking NCF1 exhibit reduced growth of implanted melanoma and carcinoma tumors.

NCF1 NCF1C NCF1B

1.51e-08387324358335
Pubmed

Molecular characterization of the mouse p47-phox (Ncf1) gene and comparative analysis of the mouse p47-phox (Ncf1) gene to the human NCF1 gene.

NCF1 NCF1C NCF1B

1.51e-08387310891396
Pubmed

P47phox-/- mice are compromised in expansion and activation of CD8+ T cells and susceptible to Trypanosoma cruzi infection.

NCF1 NCF1C NCF1B

1.51e-08387325474113
Pubmed

NADPH oxidase in bone marrow-derived cells mediates pulmonary ischemia-reperfusion injury.

NCF1 NCF1C NCF1B

1.51e-08387318787174
Pubmed

NAD(P)H oxidase subunit p47phox is elevated, and p47phox knockout prevents diaphragm contractile dysfunction in heart failure.

NCF1 NCF1C NCF1B

1.51e-08387326209274
Pubmed

Deficient production of reactive oxygen species leads to severe chronic DSS-induced colitis in Ncf1/p47phox-mutant mice.

NCF1 NCF1C NCF1B

1.51e-08387324873968
Pubmed

p47(phox) is required for afferent arteriolar contractile responses to angiotensin II and perfusion pressure in mice.

NCF1 NCF1C NCF1B

1.51e-08387322184329
Pubmed

NADPH oxidase-derived free radicals are key oxidants in alcohol-induced liver disease.

NCF1 NCF1C NCF1B

1.51e-08387311018074
Pubmed

Natural Loss-of-Function Mutations in Qa2 and NCF1 Cause the Spread of Mannan-Induced Psoriasis.

NCF1 NCF1C NCF1B

1.51e-08387333545139
Pubmed

Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis.

NCF1 NCF1C NCF1B

1.51e-08387320142487
Pubmed

Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.51e-0838739116268
Pubmed

Mice producing less reactive oxygen species are relatively resistant to collagen glycopeptide vaccination against arthritis.

NCF1 NCF1C NCF1B

1.51e-08387320686129
Pubmed

Angiotensin II induced catabolic effect and muscle atrophy are redox dependent.

NCF1 NCF1C NCF1B

1.51e-08387321570954
Pubmed

p47(phox) contributes to albuminuria and kidney fibrosis in mice.

NCF1 NCF1C NCF1B

1.51e-08387325565313
Pubmed

Knockout of neutrophil cytosolic factor 1 ameliorates neuroinflammation and motor deficit after traumatic brain injury.

NCF1 NCF1C NCF1B

1.51e-08387339357591
Pubmed

Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion.

NCF1 NCF1C NCF1B

1.51e-08387312958309
Pubmed

Genetic demonstration of p47phox-dependent superoxide anion production in murine vascular smooth muscle cells.

NCF1 NCF1C NCF1B

1.51e-08387311435342
Pubmed

Neutrophil Cytosolic Factor 1 in Dendritic Cells Promotes Autoreactive CD8+ T Cell Activation via Cross-Presentation in Type 1 Diabetes.

NCF1 NCF1C NCF1B

1.51e-08387331118934
Pubmed

Female mice lacking p47phox have altered adipose tissue gene expression and are protected against high fat-induced obesity.

NCF1 NCF1C NCF1B

1.51e-08387323482812
Pubmed

Virulence comparisons of Aspergillus nidulans mutants are confounded by the inflammatory response of p47phox-/- mice.

NCF1 NCF1C NCF1B

1.51e-08387316041040
Pubmed

The p47(phox-/-) mouse model of chronic granulomatous disease has normal granuloma formation and cytokine responses to Mycobacterium avium and Schistosoma mansoni eggs.

NCF1 NCF1C NCF1B

1.51e-08387310085000
Pubmed

Oxidants from nicotinamide adenine dinucleotide phosphate oxidase are involved in triggering cell proliferation in the liver due to peroxisome proliferators.

NCF1 NCF1C NCF1B

1.51e-08387310987289
Pubmed

Methamphetamine alters occludin expression via NADPH oxidase-induced oxidative insult and intact caveolae.

NCF1 NCF1C NCF1B

1.51e-08387321435178
Pubmed

Intermittent hypoxia has organ-specific effects on oxidative stress.

NCF1 NCF1C NCF1B

1.51e-08387318703411
Pubmed

Mycobacterial infection induces higher interleukin-1β and dysregulated lung inflammation in mice with defective leukocyte NADPH oxidase.

NCF1 NCF1C NCF1B

1.51e-08387329228045
Pubmed

Mycobacteria-induced Gr-1+ subsets from distinct myeloid lineages have opposite effects on T cell expansion.

NCF1 NCF1C NCF1B

1.51e-08387317307863
Pubmed

Generation of reactive oxygen species (ROS) is a key factor for stimulation of macrophage proliferation by ceramide 1-phosphate.

NCF1 NCF1C NCF1B

1.51e-08387322155727
Pubmed

Ncf1 affects osteoclast formation but is not critical for postmenopausal bone loss.

NCF1 NCF1C NCF1B

1.51e-08387327829407
Pubmed

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction.

NCF1 NCF1C NCF1B

1.51e-08387324576409
Pubmed

The presence of p47phox in liver parenchymal cells is a key mediator in the pathogenesis of alcoholic liver steatosis.

NCF1 NCF1C NCF1B

1.51e-08387322376231
Pubmed

Leishmania amazonensis amastigotes trigger neutrophil activation but resist neutrophil microbicidal mechanisms.

NCF1 NCF1C NCF1B

1.51e-08387323918780
Pubmed

NADPH oxidase NOX2 mediates TLR2/6-dependent release of GM-CSF from endothelial cells.

NCF1 NCF1C NCF1B

1.51e-08387328274989
Pubmed

The p47phox deficiency significantly attenuates the pathogenicity of Chlamydia muridarum in the mouse oviduct but not uterine tissues.

NCF1 NCF1C NCF1B

1.51e-08387326645958
Pubmed

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

NCF1 NCF1C NCF1B

1.51e-08387312364355
Pubmed

NADPH oxidase promotes neutrophil extracellular trap formation in pulmonary aspergillosis.

NCF1 NCF1C NCF1B

1.51e-08387324549323
Pubmed

NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities.

NCF1 NCF1C NCF1B

1.51e-08387334557202
Pubmed

Reactive Oxygen Species Regulate Both Priming and Established Arthritis, but with Different Mechanisms.

NCF1 NCF1C NCF1B

1.51e-08387328467721
Pubmed

P47(phox)-deficient NADPH oxidase defect in neutrophils of diabetic mouse strains, C57BL/6J-m db/db and db/+.

NCF1 NCF1C NCF1B

1.51e-08387310670582
Pubmed

NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

NCF1 NCF1C NCF1B

1.51e-08387320881184
Pubmed

Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes.

NCF1 NCF1C NCF1B

1.51e-08387326528554
Pubmed

The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis.

NCF1 NCF1C NCF1B

1.51e-08387319052348
Pubmed

Effect of early particulate air pollution exposure on obesity in mice: role of p47phox.

NCF1 NCF1C NCF1B

1.51e-08387320864666
Pubmed

Reactive oxygen species delay control of lymphocytic choriomeningitis virus.

NCF1 NCF1C NCF1B

1.51e-08387323328631
Pubmed

p47phox-Dependent Oxidant Signalling through ASK1, MKK3/6 and MAPKs in Angiotensin II-Induced Cardiac Hypertrophy and Apoptosis.

NCF1 NCF1C NCF1B

1.51e-08387334572995
Pubmed

Acid aspiration-induced lung inflammation and injury are exacerbated in NADPH oxidase-deficient mice.

NCF1 NCF1C NCF1B

1.51e-08387317114280
Pubmed

Participation of mitochondrial respiratory complex III in neutrophil activation and lung injury.

NCF1 NCF1C NCF1B

1.51e-08387319168575
Pubmed

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

NCF1 NCF1C NCF1B

1.51e-08387325989352
Pubmed

NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation.

NCF1 NCF1C NCF1B

1.51e-08387319503084
Pubmed

Hypoglycemic neuronal death is triggered by glucose reperfusion and activation of neuronal NADPH oxidase.

NCF1 NCF1C NCF1B

1.51e-08387317404617
Pubmed

Critical role of the NAD(P)H oxidase subunit p47phox for left ventricular remodeling/dysfunction and survival after myocardial infarction.

NCF1 NCF1C NCF1B

1.51e-08387317332431
Pubmed

Lpp of Escherichia coli K1 inhibits host ROS production to counteract neutrophil-mediated elimination.

NCF1 NCF1C NCF1B

1.51e-08387336592568
Pubmed

Genetic requirement of p47phox for superoxide production by murine microglia.

NCF1 NCF1C NCF1B

1.51e-08387311156938
Pubmed

Tumour-elicited neutrophils engage mitochondrial metabolism to circumvent nutrient limitations and maintain immune suppression.

NCF1 NCF1C NCF1B

1.51e-08387330504842
Pubmed

Genomic structure of the human p47-phox (NCF1) gene.

NCF1 NCF1C NCF1B

1.51e-08387310772875
Pubmed

A Feed-Forward Mechanism Involving the NOX Complex and RyR-Mediated Ca2+ Release During Axonal Specification.

NCF1 NCF1C NCF1B

1.51e-08387327798190
Pubmed

Endothelium-dependent coronary vasodilatation requires NADPH oxidase-derived reactive oxygen species.

NCF1 NCF1C NCF1B

1.51e-08387320702812
Pubmed

Direct interaction of HIV gp120 with neuronal CXCR4 and CCR5 receptors induces cofilin-actin rod pathology via a cellular prion protein- and NOX-dependent mechanism.

NCF1 NCF1C NCF1B

1.51e-08387333705493
Pubmed

Inhibition of NADPH oxidase by apocynin attenuates progression of atherosclerosis.

NCF1 NCF1C NCF1B

1.51e-08387323965970
Pubmed

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

NCF1 NCF1C NCF1B

1.51e-08387326455429
Pubmed

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice.

NCF1 NCF1C NCF1B

1.51e-08387315513930
Pubmed

Conditional haploinsufficiency of NCF1 (encoding p47(phox)), a signaling gene with a heterozygous phenotype potentially subject to natural selection.

NCF1 NCF1C NCF1B

1.51e-08387315626477
Pubmed

Phosphoinositide 3-kinase regulates the phosphorylation of NADPH oxidase component p47(phox) by controlling cPKC/PKCdelta but not Akt.

NCF1 NCF1C NCF1B

1.51e-08387315033459
Pubmed

NCF1 gene and pseudogene pattern: association with parasitic infection and autoimmunity.

NCF1 NCF1C NCF1B

1.51e-08387319077231
Pubmed

Neutrophil-derived ROS contribute to oxidative DNA damage induction by quartz particles.

NCF1 NCF1C NCF1B

1.51e-08387320828610
Pubmed

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation.

NCF1 NCF1C NCF1B

1.51e-08387320817944
Pubmed

Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome.

NCF1 NCF1C NCF1B

1.51e-08387322319452
Pubmed

Early determinants of H2O2-induced endothelial dysfunction.

NCF1 NCF1C NCF1B

1.51e-08387316895801
Pubmed

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis.

NCF1 NCF1C NCF1B

1.51e-08387320690191
Pubmed

Endosomal acidification and activation of NADPH oxidase isoforms are upstream events in hyperosmolarity-induced hepatocyte apoptosis.

NCF1 NCF1C NCF1B

1.51e-08387316772302
Pubmed

Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice.

NCF1 NCF1C NCF1B

1.51e-08387332504071
Pubmed

Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells.

NCF1 NCF1C NCF1B

1.51e-08387316280459
Pubmed

Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.51e-08387318185592
Pubmed

NCF1-dependent production of ROS protects against lupus by regulating plasmacytoid dendritic cell development and functions.

NCF1 NCF1C NCF1B

1.51e-08387336853827
Pubmed

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

NCF1 NCF1C NCF1B

1.51e-08387323024271
Pubmed

Ncf1 (p47phox) is essential for direct regulatory T cell mediated suppression of CD4+ effector T cells.

NCF1 NCF1C NCF1B

1.51e-08387321253614
Pubmed

Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.

NCF1 NCF1C NCF1B

1.51e-08387325873172
Pubmed

Enhanced autoimmunity, arthritis, and encephalomyelitis in mice with a reduced oxidative burst due to a mutation in the Ncf1 gene.

NCF1 NCF1C NCF1B

1.51e-08387315310853
Pubmed

Exogenous PP2A inhibitor exacerbates the progression of nonalcoholic fatty liver disease via NOX2-dependent activation of miR21.

NCF1 NCF1C NCF1B

1.51e-08387331393787
Pubmed

Vascular effects following homozygous disruption of p47(phox) : An essential component of NADPH oxidase.

NCF1 NCF1C NCF1B

1.51e-08387310725280
Pubmed

Ncf1 Governs Immune Niches in the Lung to Mediate Pulmonary Inflammation in Mice.

NCF1 NCF1C NCF1B

1.51e-08387334970267
Pubmed

Germ-free mice deficient of reactive oxygen species have increased arthritis susceptibility.

NCF1 NCF1C NCF1B

1.51e-08387325689796
Pubmed

Opposing roles of p47phox in basal versus angiotensin II-stimulated alterations in vascular O2- production, vascular tone, and mitogen-activated protein kinase activation.

NCF1 NCF1C NCF1B

1.51e-08387314993144
Pubmed

Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

NCF1 NCF1C NCF1B

1.51e-08387322050439
Pubmed

The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.

NCF1 NCF1C NCF1B

1.51e-08387312031896
Pubmed

NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesion.

NCF1 NCF1C NCF1B

1.51e-08387311249873
Pubmed

Ncf1 (p47phox) polymorphism determines oxidative burst and the severity of arthritis in rats and mice.

NCF1 NCF1C NCF1B

1.51e-08387315936744
Pubmed

NADPH oxidase modulates myocardial Akt, ERK1/2 activation, and angiogenesis after hypoxia-reoxygenation.

NCF1 NCF1C NCF1B

1.51e-08387317220182
Pubmed

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse.

NCF1 NCF1C NCF1B

1.51e-08387325628043
Pubmed

The p47phox mouse knock-out model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.51e-0838737650482
Pubmed

Disseminated trichosporonosis in a murine model of chronic granulomatous disease.

NCF1 NCF1C NCF1B

1.51e-08387312868577
InteractionFEV interactions

TCF20 SATB1 GTF3C2 ZFHX4 MIDEAS EP300 PHF21A HOMEZ

7.87e-07203748int:FEV
InteractionCSNK2A2 interactions

RAF1 BRPF3 IL16 LATS1 HMGA2 TCF20 G3BP1 TCOF1 NCF1 AUTS2 ZC3H18 FAM90A1 EP300

1.89e-067187413int:CSNK2A2
InteractionACTN3 interactions

RAF1 LZTR1 LATS1 MICALL2 CDC73 FAM90A1

2.99e-06109746int:ACTN3
InteractionTLX1 interactions

TCF20 SATB1 ZFHX4 AUTS2 MIDEAS EP300 HOMEZ

3.64e-06175747int:TLX1
InteractionTBXT interactions

TCF20 SATB1 ZFHX4 MIDEAS EP300 HOMEZ

4.30e-06116746int:TBXT
InteractionPAX9 interactions

TCF20 SATB1 ZFHX4 MIDEAS EP300 HOMEZ

8.30e-06130746int:PAX9
InteractionFAM90A26 interactions

FAM90A26 FAM90A1

1.33e-052742int:FAM90A26
InteractionSP7 interactions

FBN2 TCF20 SATB1 ZFHX4 ZMIZ1 MIDEAS EP300 HOMEZ

1.55e-05304748int:SP7
InteractionPIAS3 interactions

HMGA2 SATB1 SREBF2 ZMIZ1 EP300

2.61e-0595745int:PIAS3
InteractionMYH13 interactions

RAF1 LZTR1 LATS1 PHF21A

2.88e-0548744int:MYH13
InteractionLUC7L interactions

RAF1 CASC3 GTF3C2 G3BP1 NEK7 ZC3H18 EP300

3.00e-05242747int:LUC7L
InteractionKDM1A interactions

RAF1 IL16 TCF20 SATB1 GTF3C2 ZFHX4 PHF20L1 SH3D19 ZMIZ1 EP300 PHF21A HOMEZ NPAT

3.42e-059417413int:KDM1A
InteractionDVL2 interactions

RAF1 WASL BRPF3 LATS1 TCF20 EML5 AAK1 FAM90A1 EP300 PHF21A

3.52e-055577410int:DVL2
InteractionMEAF6 interactions

RAF1 KLF8 BRPF3 SREBF2 ZC3H18

4.03e-05104745int:MEAF6
InteractionCRX interactions

MYO15B TCF20 ZFHX4 ZMIZ1 MIDEAS EP300 HOMEZ

4.08e-05254747int:CRX
InteractionTBR1 interactions

LATS1 ZFHX4 ZMIZ1 MIDEAS EP300

6.00e-05113745int:TBR1
InteractionCLTB interactions

RAF1 TCF20 SH3D19 AAK1 OBSCN MIDEAS

6.09e-05185746int:CLTB
InteractionBOLA2 interactions

IL16 SLITRK5 ZC3H18 MOBP EP300

6.80e-05116745int:BOLA2
InteractionHDAC2 interactions

RAF1 KLF8 TCF20 SATB1 PHF20L1 G3BP1 NEK7 ZC3H18 CDC73 MIDEAS EP300 PHF21A

6.84e-058657412int:HDAC2
InteractionGOLGA2 interactions

RAF1 IL16 LZTR1 LATS1 TCF20 COG1 CCDC87 CCDC187 CDC73 FAM90A1 EP300

7.08e-057337411int:GOLGA2
InteractionLGALS4 interactions

RAF1 MICALL2 HOMEZ

7.98e-0523743int:LGALS4
InteractionANXA6 interactions

RAF1 IL16 G3BP1 TJP1 CDC73

8.31e-05121745int:ANXA6
InteractionPAX7 interactions

SATB1 ZFHX4 CTTN MIDEAS EP300

9.33e-05124745int:PAX7
InteractionDCD interactions

RAF1 G3BP1 MICALL2 ZC3H18 CDC73 EP300

9.90e-05202746int:DCD
InteractionPFN1 interactions

RAF1 WASL COG1 TJP1 SH3D19 AAK1 NAA80 ZC3H18 CDC73

1.00e-04509749int:PFN1
InteractionTRIM27 interactions

BRPF3 IL16 MAGEL2 MYO15B TCF20 CCDC87 CCDC187 FAM90A1 MIDEAS

1.08e-04514749int:TRIM27
InteractionRBM26 interactions

RAF1 GTF3C2 G3BP1 TJP1 EP300

1.17e-04130745int:RBM26
InteractionAMOT interactions

LATS1 PHF20L1 TJP1 CTTN MAP4K4 EP300 PHF21A

1.48e-04312747int:AMOT
InteractionWWTR1 interactions

IL16 LATS1 TCF20 GTF3C2 TJP1 SH3D19 MAP4K4 EP300

1.56e-04422748int:WWTR1
InteractionBICD2 interactions

WASL MAST4 TJP1 AAK1 CCDC187 CTTN MAP4K4 PHF21A

1.66e-04426748int:BICD2
InteractionYWHAH interactions

RAF1 CASC3 PDE3B LATS1 MAST4 TCF20 G3BP1 TJP1 SH3D19 AAK1 MAP4K4 WNK2 HOMEZ

1.69e-0411027413int:YWHAH
InteractionGAPDH interactions

RAF1 CASC3 MAGEL2 G3BP1 MICALL2 OBSCN ZC3H18 CDC73 EP300 NPAT

1.97e-046867410int:GAPDH
InteractionPTBP1 interactions

RAF1 HMGA2 G3BP1 TJP1 ZC3H18 ZMIZ1 CTTN EP300

1.98e-04437748int:PTBP1
InteractionZYX interactions

LATS1 TJP1 SH3D19 AAK1 SREBF2 EP300 PHF21A

2.04e-04329747int:ZYX
InteractionSFN interactions

RAF1 LATS1 MAST4 G3BP1 TJP1 SH3D19 AAK1 ZC3H18 CDC73 MAP4K4

2.11e-046927410int:SFN
InteractionSOX7 interactions

TCF20 ZFHX4 EP300 PHF21A

2.36e-0482744int:SOX7
InteractionSRRT interactions

RAF1 EPS8L2 G3BP1 EVPL ZC3H18 CTTN EP300

2.50e-04340747int:SRRT
InteractionAKAP8L interactions

RAF1 KLF8 BRPF3 LATS1 ZC3H18 PHF21A

2.52e-04240746int:AKAP8L
InteractionSTAT1 interactions

RAF1 LZTR1 CSF2RB G3BP1 SLITRK5 CTTN EP300

2.59e-04342747int:STAT1
InteractionEYA4 interactions

RAF1 AAK1 AUTS2 ZMIZ1 MIDEAS EP300

2.70e-04243746int:EYA4
InteractionLCK interactions

RAF1 WASL CD3E CSF2RB G3BP1 COG1 MAP4K4 EP300

2.92e-04463748int:LCK
InteractionGSC interactions

ZFHX4 AUTS2 MIDEAS EP300

2.96e-0487744int:GSC
InteractionLARP1 interactions

RAF1 KLF8 WASL MAGEL2 G3BP1 NEK7 ZC3H18 EP300

3.01e-04465748int:LARP1
InteractionSOX5 interactions

KLF8 TCF20 SATB1 ZFHX4 G3BP1

3.25e-04162745int:SOX5
InteractionKIFC3 interactions

IL16 MYO15B CCDC187 CTTN FAM90A1 HOMEZ

3.28e-04252746int:KIFC3
InteractionCPSF1 interactions

RAF1 LATS1 TCF20 ZC3H18 CDC73 EP300

3.49e-04255746int:CPSF1
InteractionERAS interactions

RAF1 MYO15B

3.67e-048742int:ERAS
InteractionZNF469 interactions

ZNF469 EP300

3.67e-048742int:ZNF469
InteractionRERE interactions

LZTR1 PHF20L1 AUTS2 EP300

3.82e-0493744int:RERE
InteractionHMGN1 interactions

RAF1 G3BP1 OBSCN ZC3H18 EP300

3.84e-04168745int:HMGN1
InteractionPAX6 interactions

SATB1 GTF3C2 ZFHX4 MIDEAS EP300 PHF21A HOMEZ

3.90e-04366747int:PAX6
InteractionKHDRBS3 interactions

RAF1 G3BP1 CCDC187 ZC3H18

3.98e-0494744int:KHDRBS3
InteractionNUDT21 interactions

RAF1 TJP1 SREBF2 ZC3H18 CTTN FAM90A1 EP300

4.09e-04369747int:NUDT21
InteractionPHF5A interactions

RAF1 LATS1 G3BP1 ZC3H18 CDC73

4.17e-04171745int:PHF5A
InteractionEGR2 interactions

ZFHX4 MIDEAS EP300 PHF21A HOMEZ

4.17e-04171745int:EGR2
InteractionAKT1 interactions

RAF1 CASC3 PDE3B TCOF1 NCF1 CTTN NCF1C MAP4K4 EP300

4.18e-04617749int:AKT1
InteractionACTA1 interactions

WASL EPS8L2 LATS1 TJP1 APC2 CTTN EP300

4.23e-04371747int:ACTA1
InteractionDPM1 interactions

RAF1 LATS1 ZC3H18 MIDEAS EP300

4.39e-04173745int:DPM1
InteractionDMPK interactions

RAF1 LATS1 CDC73

4.58e-0441743int:DMPK
InteractionCSNK2B interactions

RAF1 TCOF1 TJP1 NCF1 AUTS2 CCDC187 ZC3H18 MAP4K4 EP300

4.59e-04625749int:CSNK2B
InteractionPCNA interactions

RAF1 KLF8 G3BP1 TCOF1 OBSCN NEK7 CDC73 EP300

4.68e-04497748int:PCNA
InteractionNCF1C interactions

NCF1 NCF1C

4.71e-049742int:NCF1C
InteractionTEAD1 interactions

SATB1 ZFHX4 CTTN MIDEAS EP300

4.75e-04176745int:TEAD1
InteractionSNRNP40 interactions

RAF1 TCF20 PHF20L1 TCOF1 RBM6 ZC3H18 MIDEAS PHF21A NPAT

5.27e-04637749int:SNRNP40
InteractionGABPB1 interactions

IL16 FAM90A1 EP300

5.28e-0443743int:GABPB1
InteractionRBBP7 interactions

TCF20 PHF20L1 TCOF1 NCF1 SREBF2 ZC3H18 EP300 NPAT

5.34e-04507748int:RBBP7
InteractionZMIZ1 interactions

SATB1 ZMIZ1 PHF21A

5.65e-0444743int:ZMIZ1
InteractionMYBPC1 interactions

RAF1 LATS1 NCF1

5.65e-0444743int:MYBPC1
InteractionH1-10 interactions

G3BP1 SREBF2 ZC3H18 CTTN FAM90A1 MAP4K4

5.73e-04280746int:H1-10
InteractionMAPRE1 interactions

CASC3 MAST4 G3BP1 SH3D19 APC2 WDR90 CTTN EP300

5.84e-04514748int:MAPRE1
Cytoband8p23.1

FAM90A14 FAM90A17 FAM90A19 FAM90A23 FAM90A2P FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

9.47e-1515487118p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

FAM90A14 FAM90A17 FAM90A19 FAM90A23 FAM90A2P FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

9.49e-132348711chr8p23
Cytoband7q11.23

NCF1 NCF1C NCF1B

8.52e-04978737q11.23
CytobandEnsembl 112 genes in cytogenetic band chr7q11

NCF1 AUTS2 NCF1C NCF1B

1.80e-03271874chr7q11
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZFHX4 HOMEZ

8.00e-0415512529
GeneFamilyGCN5 related N-acetyltransferases

NAA80 SATL1

2.07e-03245121134
GeneFamilyPHD finger proteins

BRPF3 PHF20L1 PHF21A

2.09e-039051388
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WASL EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

5.51e-081997775a1557fe35aa48080d4967e8724bf27f9585a5fb
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WASL EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

5.51e-081997770a657475b92aa3a713da62da364525249fdc3886
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WASL EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

5.51e-08199777a8f4bd0e65f36b29535864fae4347369d5c864d2
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WASL EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

5.51e-08199777eacea42e973f073b410f54c0a1b3a7f2dc2b5a29
ToppCellNS-critical-d_0-4-Lymphoid-Treg|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL16 PDE3B CD3E TMIGD2 AAK1 RBM6

7.78e-07183776f478dfa231fc1b12ead0183cc9d22077cdf43d1f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1 OBSCN

8.03e-071847765350b58aa9979631228835d11eb45ddf81d08bff
ToppCellNS-critical-d_0-4-Lymphoid|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL16 PDE3B CD3E AAK1 RBM6 AUTS2

9.69e-0719077684f9f5ac29ff0f929a589b76efa61d4c570e76b0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 G3BP1 AAK1 NPAT

1.03e-061927761c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

1.23e-06198776fb3965049cb1961de0d2e74370868e46aa5050c8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

1.23e-0619877672d91bd0c727ecadc41e023a16c9326158db1b7b
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

1.23e-06198776441608034c787e55691558a480dcd07e37419138
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

EPS8L2 TJP1 SH3D19 EVPL FUT3 CTTN

1.23e-061987769f5726aedd1fb132feab717a029fa302306461b5
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

PDE3B MYO15B HMGA2 EML5 OBSCN NAA80

1.31e-062007766b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCellHealthy/Control-CD8+_T_naive|World / Disease group and Cell class

PDE3B CD3E EML5 TMIGD2 FAM90A1

8.08e-0615877570680b29428b6bf882b1fae36f924b775961176b
ToppCell10x5'-blood-Lymphocytic_Invariant-Inducer-like-MAIT|blood / Manually curated celltypes from each tissue

PDE3B CD3E SATB1 TMIGD2 SLITRK5

1.32e-05175775b4e4b66e89f79999768a6192c8404cb2465f920b
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 PDE3B CD3E EML5 SATB1

1.44e-05178775a9a8567d8fdc0fffd612fee16b5b29ef7b1c9307
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD4+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL16 PDE3B CD3E EML5 SATB1

1.44e-051787755ecbea15efd304057aef826ec2f385997bfaf0c9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

1.44e-0517877531c847d7f7aa0f6d820afbb45d507992f5e9dc2f
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK-CD8_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IL16 CD3E SATB1 TMIGD2 AAK1

1.48e-051797754e9e0deabf9b09ffcf30fed6d5eae72ce0ef2f1f
ToppCellRV|World / Chamber and Cluster_Paper

FBN2 AAK1 OBSCN CPEB3 NRG2

1.56e-05181775bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-Progen-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD3E SATB1 ABI3BP TMIGD2 AAK1

1.56e-0518177555fcefa234c8fc707b23248e724756d69827cd18
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

1.60e-051827753a3ed195c15d33d46a2f395cb93018e4bba28353
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

1.64e-05183775f2ef110bf29b1a8276ef216238363e542db262c1
ToppCellremission-CD8+_T_naive|World / disease stage, cell group and cell class

PDE3B CD3E SATB1 AAK1 NPAT

1.73e-0518577569304d7dd406ac7e96d51c239d7035a06d88704f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

1.78e-05186775c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic-Progen|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD3E SATB1 ABI3BP TMIGD2 AAK1

1.82e-0518777516fffe894a2c7d5186556ad000e0be229511fbdb
ToppCellsystemic_lupus_erythematosus-flare-Hematopoietic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD3E SATB1 ABI3BP TMIGD2 AAK1

1.87e-0518877588b808561ebde997ac8a8bbd1d9bbda49bbb6646
ToppCellLV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

FBN2 MAST4 AAK1 OBSCN WNK2

1.87e-051887750758b474457efa36488e0195f7357100f4b6a090
ToppCellNS-critical-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PDE3B CD3E AAK1 RBM6 AUTS2

1.92e-05189775fb7572fb4c7c43886d57a025decad076f32a14c4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

1.92e-05189775e9df7ecd36bee1fedce23bb188c68a94fa60462c
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-SELL+_CD8_T|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE3B CD3E SATB1 TMIGD2 AAK1

1.92e-05189775e9f66bf288aac04602206f058f5b7af75b1ffdab
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 G3BP1 AAK1

2.02e-051917759bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-05191775f398344aaa79fc93d792e241b634a6afe4aff33d
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-05191775d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-0519177511da47d96f44ba629e3299667495e7daddbbe86c
ToppCellsevere_COVID-19-CD4+_T_naive|World / disease group, cell group and cell class (v2)

PDE3B CD3E SATB1 TMIGD2 FUT3

2.02e-0519177555a282478488efd1561ea57a6f0218f55f711bb0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-05191775696921a4f160b6b55698652488ed781e855e5e51
ToppCellCOVID-19_Moderate-CD8+_T_naive|World / disease group, cell group and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-05191775c3385226915097f47d2f197166fc755227438524
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-05191775ffcb2c8dbcf40281b439f4b719b5b341972ffb9a
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-05191775fda432a7f79664e8ffd5d03c1c69ec43bbac994b
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.02e-05191775ffe88d1ad676c745c76db89f766062fd365329f4
ToppCellNS-critical-d_07-13-Lymphoid-Treg|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL16 PDE3B CD3E TMIGD2 AAK1

2.07e-05192775cd34defac6565d34db507918e791b09c79f7d1f8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.07e-05192775ef8970e5389bd55c1624cd6dd01a7ca7abaa8950
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Convalescent / Disease group, lineage and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.07e-05192775ad7207810116e73d461242e42071901b6a9f48c6
ToppCellremission-CD4+_T_naive|remission / disease stage, cell group and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.07e-05192775d96b2122e28c735d8002ad6eb2d3d52c8e9ccf2b
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.12e-0519377595f5611dd9583f339b7c9f52bb478af204fb89ad
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

IL16 ZFHX4 ABI3BP ARHGAP10 SLITRK5

2.12e-0519377509a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellCF-Epithelial|CF / Disease state, Lineage and Cell class

EPS8L2 TJP1 EVPL FUT3 CTTN

2.12e-05193775518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.12e-051937752946e8c9328e356cda3dafe7c86e8de462df37da
ToppCellCF-Epithelial-Epithelial_cell|CF / Disease state, Lineage and Cell class

EPS8L2 TJP1 EVPL FUT3 CTTN

2.12e-051937754e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.12e-051937751559d25b3f1c4ea268478ac26ba13f166b96f1dc
ToppCellHealthy_donor-CD4+_T_naive|World / disease group, cell group and cell class (v2)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.17e-05194775bcaaa6b6ce5b3552f11311d8ee91c35b8ec065f8
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.17e-051947752e2019a7bf57f257f0ff9b24eacff59dbb952ebb
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NCF1 SREBF2 NCF1C MAP4K4 NCF1B

2.17e-05194775ff661419b697aef51a53fdeac8d37d870d65f491
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.17e-05194775d788d5bd1e651706e7e2d54ada546a5e84f86ff0
ToppCellsevere_COVID-19-CD4+_T_naive|severe_COVID-19 / disease group, cell group and cell class (v2)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.17e-051947754b86f3cc173ea779399d5b3598b45b25f60a4395
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.17e-05194775e0ccf18edbae09fc1068f1e923f1bc0d0ff44195
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.17e-05194775fc0504730ae576ff46ba0bc9f585c53ab78d914c
ToppCellControl-Lymphoid_T/NK-CD4+_T_naive|Control / Disease group, lineage and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.17e-05194775aabcd9f71d8ef54add5c46d8a3e226e3ae3ab124
ToppCellcritical-Lymphoid-Treg|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IL16 PDE3B CD3E TMIGD2 AAK1

2.17e-05194775deaae292972371b6afae58a023fe2fc05b351bda
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IL16 CD3E SATB1 TMIGD2 AAK1

2.23e-05195775146e482f660c0f234a3d15495ad9e7ed7b88fdc8
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

PDE3B CD3E MAST4 SATB1 OBSCN

2.23e-051957754bdedd924564a260841a9153604026b57487c83d
ToppCellmetastatic_Lymph_Node-T/NK_cells-Naive_CD4+_T|metastatic_Lymph_Node / Location, Cell class and cell subclass

PDE3B CD3E SATB1 TMIGD2 AAK1

2.23e-05195775c72943618ced6797202894f78fbb8f300c2e4387
ToppCell10x3'2.3-week_14-16-Lymphocytic_T|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

IL16 CD3E SATB1 TMIGD2 AAK1

2.23e-05195775efc71886b8521539dcba9d5c1a8304eec2dc6c42
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE3B CD3E SATB1 TMIGD2 AAK1

2.23e-051957759c71d2a58e772b556e22e2f1d60593580b7aafd8
ToppCellCOVID-19_Moderate-CD8+_T_naive|COVID-19_Moderate / disease group, cell group and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.23e-0519577522fdc8876883c6b00049ed978260e11f02209b3a
ToppCellsystemic_lupus_erythematosus-managed-Hematopoietic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

CD3E HMGA2 SATB1 TMIGD2 MED12L

2.28e-05196775a6fcd4f9a39f8e4ff3076735dd615311104dfd1d
ToppCellnormal_Lymph_Node-T/NK_cells-Naive_CD4+_T|normal_Lymph_Node / Location, Cell class and cell subclass

PDE3B CD3E SATB1 TMIGD2 AAK1

2.34e-05197775a25954c534da16d5ce57cfe3a3a01beb2f556a5c
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.34e-051977759373fcd728016b7af1abd7d88c47b7db79eb6a2f
ToppCellIIF-Lymphocyte-T_NK-CD8_Naive|IIF / Disease, Lineage and Cell Type

PDE3B CD3E SATB1 TMIGD2 AAK1

2.34e-05197775fa376bde80ed0ae57ae064ff7165cfb870724b93
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD8_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 CD3E SATB1 TMIGD2 AAK1

2.40e-051987750dac00a64fe08ec6669af3ddd4b82413b673233d
ToppCellNS-critical-LOC-Lymphoid-CTL|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL16 PDE3B CD3E SATB1 AAK1

2.40e-05198775e2acb074142aa62c763139bbcf36f6f85038d04b
ToppCellcellseq2-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 PDE3B CD3E NCF1 AAK1

2.40e-0519877567e297b3f305d136ff586f68b618e25c902dbcb7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.40e-05198775239bef79ebaa6e1d8618c670c1050a02362058ee
ToppCellNS-critical-d_07-13|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

WASL TJP1 SH3D19 FUT3 CTTN

2.40e-05198775a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCellcellseq2-Immune-Lymphocytic_T/NK|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 PDE3B CD3E NCF1 AAK1

2.40e-05198775cb177bad587de804f98b38502a284dc267e37aff
ToppCell21-Trachea-Immune-Hematopoietic,_T_Cells|Trachea / Age, Tissue, Lineage and Cell class

IL16 CD3E SATB1 TMIGD2 AAK1

2.40e-05198775da32693a9833ffeced87fe6ec91f076648005f6d
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T8_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-0519977540eb207fa0f07e2e4d0be69530b8f61f7ea49c73
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD4_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 CD3E SATB1 TMIGD2 AAK1

2.46e-05199775b01328a80db5bb088c44564cea0f6729b1a9805b
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-T8_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-05199775fd989d9088646b3ffda9c5c9c920048f98934e07
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-0519977567b9ff07de5be0895612c201cb21e66a3f88669a
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T8_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-05199775e47f8314a4822bf00d0999316457f95c338585e1
ToppCellcontrol-CD8+_T_naive|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-051997756a61ce7404c65e506091fee99a2001f5a9b39f31
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-T8_naive|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-051997758a89d6d824f8ac5929cfabd00e63811cecb97eab
ToppCellCOVID_vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

PDE3B CD3E SATB1 TMIGD2 OBSCN

2.46e-05199775885bc902b6e2af0b61e452c4154160cd3f1cf98e
ToppCellmLN-(1)_T_cell-(14)_Tcm|mLN / shred on region, Cell_type, and subtype

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-051997753222454da504e119c78e666b90cc669ff0335b1a
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL16 CD3E SATB1 TMIGD2 AAK1

2.46e-0519977545d0d275ffb4183e3e71f4701e121ef9853ebd10
ToppCellmLN-T_cell-Tcm|mLN / Region, Cell class and subclass

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-05199775b1237c8d1acad6737d8cb425dc4eb50724e2302c
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T8_naive-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PDE3B CD3E SATB1 TMIGD2 AAK1

2.46e-051997756ed413872301707dc73ae66365bee94cd38a292c
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_naive|Control / Disease, condition lineage and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.52e-0520077559b446cd886767f19553aed779ab313685789f6f
ToppCellcontrol-MAIT|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CD3E SATB1 ARHGAP10 TMIGD2 AAK1

2.52e-05200775aeea4bda2e38cc6db571ed2b47ce022d637619bd
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD4+_T_naive|COVID-19_Convalescent / Disease, condition lineage and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.52e-05200775729873094526b7752b91470f4a7281af7d57dbf9
ToppCellMS-IIF-Lymphocyte-T/NK-CD8+_T_naive|IIF / Disease, condition lineage and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.52e-05200775350b189d0baca9516375786c3712c76c6b4fb390
ToppCellControl-Control-Lymphocyte-T/NK-CD8+_T_naive|Control / Disease, condition lineage and cell class

PDE3B CD3E SATB1 AAK1 OBSCN

2.52e-05200775906de95adc9716982ab32f216dddeb52639bad06
ToppCellcontrol-CD4+_T_naive|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.52e-052007750adb8dc3188c07a4871c6d524aab8f45dff0b14e
ToppCellControl-Control-Lymphocyte-T/NK-gd_T|Control / Disease, condition lineage and cell class

PDE3B CD3E SATB1 AAK1 AUTS2

2.52e-0520077588e502c141bbb73e62aa5830d24bd645376e5f3a
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD8+_T_naive|COVID-19_Convalescent / Disease, condition lineage and cell class

PDE3B CD3E SATB1 AAK1 NPAT

2.52e-0520077565ae349fac4084faacbc6a645a92398f6324770e
ToppCellmild-CD8+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE3B CD3E SATB1 TMIGD2 AAK1

2.52e-05200775c825320599a61a4c629d736f5c0fd6f1f405540a
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tnaive/CM_CD4|lymph-node_spleen / Manually curated celltypes from each tissue

PDE3B CD3E SATB1 TMIGD2 AAK1

2.52e-0520077539d60ec4b125b4ff905a2c6a0f2d6923b8d64227
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-immature_natural_killer_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HMGA2 TMIGD2 AUTS2 FUT3

1.20e-0414677440fac8a298152ec7f7eeeed5a2d28541aea3b338
Diseasechronic granulomatous disease (implicated_via_orthology)

NCF1 NCF1C NCF1B

1.39e-075723DOID:3265 (implicated_via_orthology)
Diseaserheumatoid arthritis (implicated_via_orthology)

NCF1 NCF1C NCF1B

3.02e-0612723DOID:7148 (implicated_via_orthology)
Diseaseinsomnia measurement

HMGA2 ADO ARHGAP10 MED12L RBM6 WDR90 EP300

1.04e-04443727EFO_0007876
DiseaseAbnormality of the skeletal system

APC2 ZMIZ1

1.63e-048722C4021790
DiseaseNoonan syndrome (is_implicated_in)

RAF1 LZTR1

1.63e-048722DOID:3490 (is_implicated_in)
Diseasebody surface area

BRPF3 FBN2 HMGA2 ADO MICALL2 AAK1 AUTS2 ZMIZ1

1.71e-04643728EFO_0022196
Diseaseresponse to tamoxifen

TCF20 SREBF2

2.09e-049722EFO_0009391
DiseaseNoonan syndrome

RAF1 LZTR1

2.09e-049722cv:C0028326
Diseasetestosterone measurement

RAF1 CASC3 KLF8 FBN2 ADO GTF3C2 ZFHX4 ARHGAP10 AUTS2 ZMIZ1 MIDEAS

2.52e-0412757211EFO_0004908
DiseaseRASopathy

RAF1 LZTR1

6.04e-0415722cv:C5555857
DiseaseC-reactive protein measurement

ZNF469 LATS1 GTF3C2 ARHGAP10 NCF1 NEK7 ZMIZ1 MAP4K4 PHF21A ARHGAP33

6.71e-0412067210EFO_0004458
DiseaseCardiovascular Abnormalities

APC2 ZMIZ1

6.89e-0416722C0243050
Diseasehair colour measurement

RAF1 ZNF469 IL16 MED12L NRG2 ZC3H18 ZMIZ1

7.54e-04615727EFO_0007822
DiseaseIntellectual Disability

KLF8 TCF20 APC2 MED12L ZMIZ1 PHF21A

7.85e-04447726C3714756
Diseasecentral corneal thickness

ZNF469 FBN2 HMGA2 TJP1 DCBLD2

9.62e-04309725EFO_0005213
Diseaseurinary albumin to creatinine ratio

ADO GTF3C2 AUTS2 ARHGAP33

9.77e-04179724EFO_0007778
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

RAF1 LZTR1

9.77e-0419722C3501846
DiseaseCostello syndrome (disorder)

RAF1 LZTR1

9.77e-0419722C0587248
DiseaseNoonan syndrome-like disorder with loose anagen hair

RAF1 LZTR1

9.77e-0419722C1843181
DiseaseCardio-facio-cutaneous syndrome

RAF1 LZTR1

9.77e-0419722C1275081
DiseaseLEOPARD Syndrome

RAF1 LZTR1

1.31e-0322722C0175704
Diseasealcohol use disorder (implicated_via_orthology)

EPS8L2 SREBF2 AUTS2 EP300

1.34e-03195724DOID:1574 (implicated_via_orthology)
DiseaseOvarian Serous Adenocarcinoma

RAF1 NEK7

1.44e-0323722C1335177
Diseasecortical surface area measurement

ZNF469 FBN2 HMGA2 MAST4 TJP1 AUTS2 MAP4K4 MOBP WNK2 PHF21A

1.53e-0313457210EFO_0010736
DiseaseNoonan Syndrome

RAF1 LZTR1

1.57e-0324722C0028326
DiseaseAdenocarcinoma of lung (disorder)

RAF1 LATS1 SATB1 EP300

1.64e-03206724C0152013
Diseasepulse pressure measurement

KLF8 BRPF3 CD3E FBN2 HMGA2 ADO ZFHX4 NEK7 FER1L5 HOMEZ

1.97e-0313927210EFO_0005763
Diseasegamma-glutamyltyrosine measurement

ARHGAP10 ZMIZ1

1.98e-0327722EFO_0021144
Diseasefree androgen index

CASC3 ZNF469 ZFHX4 ARHGAP10 ZMIZ1

2.22e-03374725EFO_0007005
Diseasecorneal topography

ZNF469 HMGA2 TJP1

2.43e-03109723EFO_0004345

Protein segments in the cluster

PeptideGeneStartEntry
QVRSPQPVPSPRPQS

EP300

2306

Q09472
RPGSPPEKRSPFPQQ

CCDC187

516

A0A096LP49
AAQPVPRPVSQARPP

CDC73

336

Q6P1J9
PRPVSQARPPPNQKK

CDC73

341

Q6P1J9
QARPPPNQKKGSRTP

CDC73

346

Q6P1J9
PVRQQPKVQTTPPPA

AAK1

596

Q2M2I8
RKATLQPLPPNLPPV

ADO

71

Q96SZ5
NALRQKLAQPPPPQP

BRPF3

776

Q9ULD4
PTRTTSPEPQKRPPQ

CCDC87

26

Q9NVE4
QKQRRAPVGPRAPPP

FAM90A10

21

A6NDY2
SQPKTPVPAQRERAP

RAF1

306

P04049
QKQRRAPVGPRSPPP

FAM90A7

21

A6NKC0
PVCNRSIPQFPVPPK

NPAT

976

Q14207
SPPNAPPRQSKRQGQ

ARHGAP10

591

A1A4S6
QKQRRAPVGPRSPPP

FAM90A23

21

A8MXZ1
SQQPPPPQQERSKPS

MAP4K4

536

O95819
SVPLPQDPMRPRQPQ

MED12L

2041

Q86YW9
RKQQPPPRTPLDQPV

LZTR1

631

Q8N653
PPVIRQAPPVIRQAP

MAGEL2

441

Q9UJ55
PPVIRQAPPVIRQAP

MAGEL2

476

Q9UJ55
PPLRQAPQARLPAPQ

MAGEL2

521

Q9UJ55
QVRSVTPPPPPRGQT

LATS1

241

O95835
PSPRPPRKAPNLTAQ

NAA80

216

Q93015
QKQRRAPVGPRAPPP

FAM90A1

21

Q86YD7
PARKPPLSPAQTNPV

MICALL2

146

Q8IY33
QKQRRAPVGPRAPPP

FAM90A14

21

P0C7W9
NVELRPPPASPQQPR

PDE3B

56

Q13370
PPVPQFQPQKALRPD

NEK7

11

Q8TDX7
TQRSKPQPAVPPRPS

NCF1

356

P14598
SQEAPPQRPSLQKPP

C19orf85

76

A0A1B0GUS0
DVAPLPQRRNPPQQP

EVPL

401

Q92817
ISRPAAPPEPRPQQQ

NRG2

56

O14511
APPEPRPQQQPQPRS

NRG2

61

O14511
ESPPPGRQPNQKTLP

IL16

921

Q14005
PQVQRPPRPQSPTQL

AUTS2

356

Q8WXX7
PRPNFLPQVRPKPVA

PHF21A

226

Q96BD5
APIRPPKPQSSPQTL

KLF8

106

O95600
QKQRRAPVGPRAPPP

FAM90A17

21

P0DV74
QKQRRAPVGPRAPPP

FAM90A16

21

P0DV73
KIRQRQSILPPPQGP

EPS8L2

191

Q9H6S3
QKQRRAPVGPRAPPP

FAM90A19

21

P0DV76
QTQRSKPQPAVPPRP

NCF1B

356

A6NI72
QTQRSKPQPAVPPRP

NCF1C

331

A8MVU1
KPVPPQPSAPESRQV

OBSCN

4621

Q5VST9
QSRPGPVPVPVQPSR

MYO15B

1096

Q96JP2
QKQRRAPVGPSAPPP

FAM90A8

21

A6NJQ4
RSDPGPPVPRLPQKQ

ARHGAP33

1196

O14559
PASQPLPRKRPPVTQ

APC2

1881

O95996
SPRSPRNNPVPPEAK

CSF2RB

776

P32927
QQQVQPKPSPPRRTP

CASC3

671

O15234
AAPRPPRAQQPQQPS

COG1

96

Q8WTW3
PPQAQPPQQRRSPAS

CPEB3

181

Q8NE35
PALQPPRRPKSSNPF

COX11

66

Q9Y6N1
QPRPESKPESQIPPQ

G3BP1

281

Q13283
SKPESQIPPQRPQRD

G3BP1

286

Q13283
RQRGQNKERPPPVPN

CD3E

171

P07766
APAQPPPARKQNVGR

MAST4

2566

O15021
KEQPPPLQPPQQSIR

MIDEAS

26

Q6PJG2
RRPQKPIPPAVPQGN

INO80D

556

Q53TQ3
RPRKQQQEPTGEPSP

HMGA2

31

P52926
PPVSRAPPQPEKLQT

EML5

1336

Q05BV3
RPPKLTQPPPPRNSN

DCBLD2

456

Q96PD2
STTVPQPQARDKPPP

HOMEZ

251

Q8IX15
QKQRRAPVGPRAPPP

FAM90A20P

21

A6NIJ5
KPPRPQPPPQQVRSA

FBN2

36

P35556
QKQRRAPVGPRAPPP

FAM90A5P

21

A8MXJ8
QKQRRAPVGPRAPPP

FAM90A24P

21

P0C7X0
INKTSPPQPVNPPRP

PHF20L1

391

A8MW92
NPKSRLPPSPRPQGQ

FUT3

116

P21217
EQTPPPQPRTAQPQK

RBM6

921

P78332
RPVNGKTIPTQQPPT

SH3D19

326

Q5HYK7
QRSPSKVKPPVRNPQ

TCOF1

821

Q13428
PPGPQVNINPRKPKR

FER1L5

1706

A0AVI2
QKQRRAPVGPRAPPP

FAM90A12P

21

A8MX19
QKQRRAPVGPRAPPP

FAM90A9

21

A6NNJ1
QKQRRAPVGPRAPPP

FAM90A13P

21

P0C7W8
QKQRRAPVGPRAPPP

FAM90A26

21

D6RGX4
LSQPVPRQPNKSPPG

SATL1

421

Q86VE3
SPQRPKQQPAAPPAV

MOBP

76

Q13875
QKQRRAPVGPRAPPP

FAM90A15P

21

P0C7V4
QQPQTGPRLPPRQPT

SATB1

616

Q01826
QPPKQPQLIGRPPSA

ZFHX4

2406

Q86UP3
RQQVPKPCQASPPRL

WDR90

1036

Q96KV7
VSPRPSPTQQPRPKG

TMIGD2

261

Q96BF3
QPNKPRVRPTSRQPS

SLITRK5

336

O94991
RAKTQTPPVSPAPQP

CTTN

396

Q14247
QKPPTAPPERQPQVD

STC2

216

O76061
RATPILQPRPQPQPQ

SREBF2

126

Q12772
QKQRRAPVGPRAPPP

FAM90A2P

21

Q658T7
KDPVTTGTPQPPQRR

TCF20

96

Q9UGU0
PNSQNKPRPPPSEQR

ZNF469

3836

Q96JG9
PPSQNKPATFRPPNR

TJP1

1476

Q07157
RTRKGPKRPQQPNPP

GTF3C2

106

Q8WUA4
PKRPQQPNPPSAPLV

GTF3C2

111

Q8WUA4
QQPPPPRRVTNVGSL

WASL

6

O00401
PRARPPVQKQASLPV

WNK2

1851

Q9Y3S1
KPKTSPRPRIPQTQP

ABI3BP

536

Q7Z7G0
LPQPNTLPPQRPKAS

UHRF1BP1

676

Q6BDS2
PGPRPQSLPIQNIKR

ZMIZ1

391

Q9ULJ6
RSPQPPSRQAEPPKK

ZC3H18

486

Q86VM9
QSPPPAKRPNTSPDR

ZC3H18

841

Q86VM9
QKQRRAPVGPRAPPP

FAM90A18

21

P0DV75
PERKQQPQLPRPPTT

KIAA1522

466

Q9P206