Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	protein kinase CK2 complex	CSNK2A1 CSNK2A3	4.52e-05	4	58	2	GO:0005956
Domain	CRAL/TRIO_N_dom	MOSPD2 SEC14L5	9.04e-04	15	56	2	IPR011074
Domain	ANK	ANKRD19P ANKRD10 ANKRD18A ASB2 ANKLE2	9.20e-04	251	56	5	SM00248
Domain	ANK_REPEAT	ANKRD19P ANKRD10 ANKRD18A ASB2 ANKLE2	9.54e-04	253	56	5	PS50088
Domain	ANK_REP_REGION	ANKRD19P ANKRD10 ANKRD18A ASB2 ANKLE2	9.70e-04	254	56	5	PS50297
Domain	Ankyrin_rpt	ANKRD19P ANKRD10 ANKRD18A ASB2 ANKLE2	1.11e-03	262	56	5	IPR002110
Domain	CRAL_TRIO	MOSPD2 SEC14L5	1.79e-03	21	56	2	PF00650
Domain	-	MOSPD2 SEC14L5	2.15e-03	23	56	2	3.40.525.10
Domain	SEC14	MOSPD2 SEC14L5	2.53e-03	25	56	2	SM00516
Domain	CRAL_TRIO	MOSPD2 SEC14L5	2.95e-03	27	56	2	PS50191
Domain	TGFb_propeptide	GDF7 GDF6	3.17e-03	28	56	2	PF00688
Domain	CRAL-TRIO_dom	MOSPD2 SEC14L5	3.17e-03	28	56	2	IPR001251
Domain	TGF-b_N	GDF7 GDF6	3.17e-03	28	56	2	IPR001111
Domain	TGF-beta-rel	GDF7 GDF6	4.13e-03	32	56	2	IPR015615
Domain	TGFb_CS	GDF7 GDF6	4.13e-03	32	56	2	IPR017948
Domain	Ank	ANKRD19P ANKRD10 ANKRD18A ASB2	4.84e-03	228	56	4	PF00023
Domain	TGFB	GDF7 GDF6	5.50e-03	37	56	2	SM00204
Domain	TGF-b_C	GDF7 GDF6	5.50e-03	37	56	2	IPR001839
Domain	TGF_BETA_2	GDF7 GDF6	5.50e-03	37	56	2	PS51362
Domain	TGF_beta	GDF7 GDF6	5.50e-03	37	56	2	PF00019
Domain	TGF_BETA_1	GDF7 GDF6	5.50e-03	37	56	2	PS00250
Domain	-	ANKRD10 ANKRD18A ASB2 ANKLE2	6.49e-03	248	56	4	1.25.40.20
Domain	Ankyrin_rpt-contain_dom	ANKRD10 ANKRD18A ASB2 ANKLE2	7.05e-03	254	56	4	IPR020683
Pubmed	Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.	CSNK2A1 CSNK2A3	3.03e-06	2	61	2	12860116
Pubmed	BMP12 and BMP13 gene transfer induce ligamentogenic differentiation in mesenchymal progenitor and anterior cruciate ligament cells.	GDF7 GDF6	3.03e-06	2	61	2	20334610
Pubmed	Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.	CSNK2A1 CSNK2A3	3.03e-06	2	61	2	14646071
Pubmed	Assignment of casein kinase 2 alpha sequences to two different human chromosomes.	CSNK2A1 CSNK2A3	3.03e-06	2	61	2	1577469
Pubmed	Molecular cloning of the human casein kinase II alpha subunit.	CSNK2A1 CSNK2A3	3.03e-06	2	61	2	2752008
Pubmed	Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.	CSNK2A1 CSNK2A3	3.03e-06	2	61	2	8420794
Pubmed	Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.	CSNK2A1 CSNK2A3	9.07e-06	3	61	2	15684395
Pubmed	Crystallization and preliminary characterization of crystals of human protein kinase CK2.	CSNK2A1 CSNK2A3	9.07e-06	3	61	2	11092945
Pubmed	Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.	CSNK2A1 CSNK2A3	9.07e-06	3	61	2	2174700
Pubmed	Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.	CSNK2A1 CSNK2A3	9.07e-06	3	61	2	12102635
Pubmed	Isolation of zebrafish gdf7 and comparative genetic mapping of genes belonging to the growth/differentiation factor 5, 6, 7 subgroup of the TGF-beta superfamily.	GDF7 GDF6	9.07e-06	3	61	2	10022976
Pubmed	Glucose-induced regulation of protein import receptor Tom22 by cytosolic and mitochondria-bound kinases.	CSNK1A1 CSNK2A1	9.07e-06	3	61	2	24093680
Pubmed	Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.	CSNK2A1 CSNK2A3	9.07e-06	3	61	2	1766873
Pubmed	Divergent activities of osteogenic BMP2, and tenogenic BMP12 and BMP13 independent of receptor binding affinities.	GDF7 GDF6	9.07e-06	3	61	2	21702718
Pubmed	Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.	CSNK2A1 CSNK2A3	9.07e-06	3	61	2	20625391
Pubmed	L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I.	CSNK1A1 CSNK2A1	1.81e-05	4	61	2	8253806
Pubmed	Phosphorylation of a vesicular monoamine transporter by casein kinase II.	CSNK1A1 CSNK2A1	1.81e-05	4	61	2	9045708
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-10 ERVK-24	1.81e-05	4	61	2	10469592
Pubmed	Phosphorylation of the beta-galactoside-binding protein galectin-3 modulates binding to its ligands.	CSNK1A1 CSNK2A1	1.81e-05	4	61	2	10961987
Pubmed	The Alzheimer's disease-associated presenilins are differentially phosphorylated proteins located predominantly within the endoplasmic reticulum.	CSNK1A1 CSNK2A1	1.81e-05	4	61	2	8972483
Pubmed	HSF1 stress response pathway regulates autophagy receptor SQSTM1/p62-associated proteostasis.	CSNK1A1 CSNK2A1	1.81e-05	4	61	2	27846364
Pubmed	Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool.	CSNK1A1 CSNK2A1	3.02e-05	5	61	2	27293189
Pubmed	Phosphorylation of protein S by platelet kinases enhances its activated protein C cofactor activity.	CSNK1A1 CSNK2A1	3.02e-05	5	61	2	23580615
Pubmed	Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.	CSNK1A1 CSNK2A1	4.52e-05	6	61	2	11583622
Pubmed	Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.	GDF7 GDF6	6.32e-05	7	61	2	8145850
Pubmed	Smad4 regulates the nuclear translocation of Nkx2-5 in cardiac differentiation.	SFRP5 CSNK2A1	6.32e-05	7	61	2	33574455
Pubmed	A DNA damage-induced p53 serine 392 kinase complex contains CK2, hSpt16, and SSRP1.	CSNK2A1 CSNK2A3	6.32e-05	7	61	2	11239457
Pubmed	Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes.	GDF7 GDF6	6.32e-05	7	61	2	12606286
Pubmed	Neuronal differentiation of precursors in the neocortical ventricular zone is triggered by BMP.	GDF7 GDF6	6.32e-05	7	61	2	9786991
Pubmed	Eukaryotic initiation factor 2B: identification of multiple phosphorylation sites in the epsilon-subunit and their functions in vivo.	CSNK1A1 CSNK2A1	6.32e-05	7	61	2	11500362
Pubmed	Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein.	CSNK1A1 CSNK2A1	6.32e-05	7	61	2	10617630
Pubmed	SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis.	CSNK1A1 CSNK2A1	6.32e-05	7	61	2	30177679
Pubmed	C-terminal phosphorylation of Hsp70 and Hsp90 regulates alternate binding to co-chaperones CHIP and HOP to determine cellular protein folding/degradation balances.	CSNK1A1 CSNK2A1	8.42e-05	8	61	2	22824801
Pubmed	Expression of testicular germ cell genes identified by differential display analysis.	ANKRD18A ANKRD18B	8.42e-05	8	61	2	12634303
Pubmed	p53 serine 392 phosphorylation increases after UV through induction of the assembly of the CK2.hSPT16.SSRP1 complex.	CSNK2A1 CSNK2A3	8.42e-05	8	61	2	12393879
Pubmed	Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses.	GDF7 GDF6	8.42e-05	8	61	2	16049014
Pubmed	Inhibition of glycogen synthase kinase-3-beta (GSK3β) blocks nucleocapsid phosphorylation and SARS-CoV-2 replication.	CSNK1A1 CSNK2A1	8.42e-05	8	61	2	36508083
Pubmed	Bmp4 from the optic vesicle specifies murine retina formation.	GDF6 FGF19	1.65e-04	11	61	2	25792196
Pubmed	Multiple and cooperative phosphorylation events regulate the CREM activator function.	CSNK1A1 CSNK2A1	1.65e-04	11	61	2	8404858
Pubmed	Neuronal patterning by BMPs: a requirement for GDF7 in the generation of a discrete class of commissural interneurons in the mouse spinal cord.	GDF7 GDF6	1.97e-04	12	61	2	9808626
Pubmed	Family with sequence similarity 60A (FAM60A) protein is a cell cycle-fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex.	ARID4A USP11 ATP2A2	1.98e-04	64	61	3	22865885
Pubmed	A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.	CNTN4 LRP2	2.33e-04	13	61	2	21079607
Pubmed	Identification and Characterization of USP7 Targets in Cancer Cells.	FBXO38 USP11	2.33e-04	13	61	2	30367141
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	MOSPD2 USP11 LRP2 MRPS9 NIPSNAP2 ANKLE2 NDUFB5 ATP2A2 TOP3B TRAK1	2.56e-04	1496	61	10	32877691
Pubmed	The effects of aging on gene expression in the hypothalamus and cortex of mice.	CSNK1A1 NDUFB5 ATP2A2	3.69e-04	79	61	3	11172053
Pubmed	Structure of human RNA polymerase III elongation complex.	POLR3E POLR2F	4.05e-04	17	61	2	33674783
Pubmed	Structural insights into RNA polymerase III-mediated transcription termination through trapping poly-deoxythymidine.	POLR3E POLR2F	4.05e-04	17	61	2	34675218
Pubmed	Structure of human RNA polymerase III.	POLR3E POLR2F	4.05e-04	17	61	2	33335104
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-24	4.55e-04	18	61	2	18664271
Pubmed	Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits.	POLR3E POLR2F	4.55e-04	18	61	2	12391170
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	FBXO38 MOSPD2 CSNK2A1 ELP2 NUP93 ANKLE2 ATP2A2 TOP3B	4.77e-04	1049	61	8	27880917
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP11 CSNK2A1	5.08e-04	19	61	2	28067227
Pubmed	Temporomandibular joint formation requires two distinct hedgehog-dependent steps.	GDF7 GDF6	6.22e-04	21	61	2	19815519
Pubmed	FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation.	GDF7 FGF19	7.48e-04	23	61	2	19668217
Pubmed	The UAS thioredoxin-like domain of UBXN7 regulates E3 ubiquitin ligase activity of RNF111/Arkadia.	FBXO38 USP11 SESN1	7.79e-04	102	61	3	37024974
Pubmed	Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.	LRP2 RENBP	8.15e-04	24	61	2	31740596
Pubmed	A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.	AMPH SFRP5	8.15e-04	24	61	2	9096311
Pubmed	USP37 is a SNAI1 deubiquitinase.	USP11 PAN2	8.15e-04	24	61	2	31911859
Pubmed	Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.	SH3PXD2A USP11 CSNK2A1 NUP93 ATP2A2	8.38e-04	418	61	5	32552912
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	USP11 CSNK2A1 MRPS9 NIPSNAP2 PARD3B ANKLE2	8.86e-04	639	61	6	23443559
Pubmed	The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.	FBXO38 MRPS9 ELP2 SESN1	9.15e-04	245	61	4	19521500
Pubmed	Tumor-derived neomorphic mutations in ASXL1 impairs the BAP1-ASXL1-FOXK1/K2 transcription network.	CSNK2A1 NUP93 ATP2A2	9.95e-04	111	61	3	32683582
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	ARID4A USP11 MRPS9 ATP2A2	1.03e-03	253	61	4	29911972
Pubmed	Same but different - Molecular comparison of human KTI12 and PSTK.	ELP2 ANKLE2	1.03e-03	27	61	2	33417976
Pubmed	Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities.	ASB2 MYO18B	1.03e-03	27	61	2	37995181
Pubmed	Suppression of epithelial differentiation by Foxi3 is essential for molar crown patterning.	SFRP5 FGF19	1.28e-03	30	61	2	26450968
Pubmed	Correct patterning of the primitive streak requires the anterior visceral endoderm.	SFRP5 GDF7	1.28e-03	30	61	2	21445260
Pubmed	FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability.	FBXO38 CSNK2A1	1.45e-03	32	61	2	35813202
Pubmed	Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.	CNTN4 LRP2	1.45e-03	32	61	2	25189868
Pubmed	Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.	USP11 PAN2	1.54e-03	33	61	2	30323974
Pubmed	The transcription factor Otx2 regulates choroid plexus development and function.	GDF7 FGF19	1.54e-03	33	61	2	23364326
Pubmed	Microphthalmia/Anophthalmia/Coloboma Spectrum – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	GDF6 POMT1	1.64e-03	34	61	2	20301552
Interaction	UVRAG interactions	POLR3E CSNK1A1 POLR2F NUP93 TOP3B	9.49e-06	97	59	5	int:UVRAG
GeneFamily	Ankyrin repeat domain containing	ANKRD10 ANKRD18A ASB2 ANKLE2 ANKRD18B	2.34e-04	242	42	5	403
GeneFamily	RNA polymerase subunits	POLR3E POLR2F	2.06e-03	29	42	2	726
GeneFamily	Ubiquitin specific peptidases	USP11 PAN2	7.49e-03	56	42	2	366
GeneFamily	Proteases, serine	PRSS12 TMPRSS11F	9.41e-03	63	42	2	738
Coexpression	BENPORATH_ES_WITH_H3K27ME3	AMPH SFRP5 GDF7 ANKRD19P PRSS12 GDF6 LRP2 CHRDL1 PARD3B CRTAC1 ANKRD18A ANKRD18B	5.82e-06	1115	59	12	M10371
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC41A2 CNTN4 GDF7 ARHGAP40 PRSS12 CRTAC1	2.50e-07	198	59	6	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC41A2 CNTN4 GDF7 ARHGAP40 PRSS12 CRTAC1	2.50e-07	198	59	6	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Tshz2-Syt2_(Layer_5a,_Entorhinal_cortex,_Tshz1+)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DNAH12 GDF7 ARHGAP40 LRP2	6.36e-07	51	59	4	adc73d6909d75ad432aef884dae540b7e48cecd6
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLCA2 PRSS12 SH3PXD2A ANKRD18B SEC14L5	3.17e-06	171	59	5	121e63ca281ad765d76c2afb3b4d441329b47f81
ToppCell	10x5'v1-week_17-19-Lymphocytic_T-T_NK-NK_T_cell\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	AMPH PLAAT4 GAL3ST2 ASB2 SESN1	4.91e-06	187	59	5	3301e0fca8c436d136c71f1a8fd59b3bb11bdd83
ToppCell	LA\|World / Chamber and Cluster_Paper	SLC41A2 CNTN4 AMPH SERPINE2 LRP2	5.72e-06	193	59	5	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Interneuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	AMPH ARID4A PRSS12 USP11 NUP93	6.80e-06	200	59	5	08bee924a2654e05df3b39e8a51f93c8b3472175
ToppCell	LPS-antiTNF-Myeloid-Monocytes,_Macrophages-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	POLR3E UVSSA RENBP SEC14L5	3.20e-05	136	59	4	186be8e1595608004b8216892cb9c7a7f31fbb4d
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CNTN4 PAN2 ASB2 ANKRD18B	4.56e-05	149	59	4	14d2e8cab97108d8fa94e540c1957b73ed32dc73
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CNTN4 PAN2 ASB2 ANKRD18B	4.56e-05	149	59	4	54c9c6282f5f5de43dfaf2972fab3e3dcf9838a3
ToppCell	Influenza_Severe-CD4+_CTL\|World / Disease group and Cell class	CRYBG2 DNAH12 PLAAT4 ANKRD18B	5.06e-05	153	59	4	0c6c2c6dbc81badd886f125f4e5ba0fb7d52101c
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SERPINE2 ASB2 MYO18B ATP2A2	7.44e-05	169	59	4	88aa2246ede582c2e11de63228d76f520889ecb3
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SERPINE2 ASB2 MYO18B ATP2A2	7.44e-05	169	59	4	a6a5b00912b653fad2ca7f096deaf35c9ef85e5b
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SERPINE2 ASB2 MYO18B ATP2A2	7.44e-05	169	59	4	42a9b8c77d2a4d68b01e4db38f8a1af53c9c814f
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC41A2 CNTN4 ARHGAP40 CRTAC1	8.71e-05	176	59	4	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AMPH SFRP5 PRSS12 USP11	8.90e-05	177	59	4	59cf56c385c324f0844f20003d2b5049a2791e45
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CNTN4 CLCA2 PRSS12 ANKRD18B	9.10e-05	178	59	4	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SLC41A2 ARHGAP40 PRSS12 CRTAC1	9.50e-05	180	59	4	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS12 SH3PXD2A GDF6 ASB2	9.91e-05	182	59	4	dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 GDF7 PRSS12 BTBD17	9.91e-05	182	59	4	398ce074a04f6482470b488f1affae4af7d2ec58
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRSS12 SH3PXD2A GDF6 ASB2	9.91e-05	182	59	4	52274af3136d4fd4a495f5882618444661421f0f
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FCRL3 PRSS12 CHRDL1 CRTAC1	1.01e-04	183	59	4	f8b636391f752e379a5c5575fd898bdf0907a3b8
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	SFRP5 LRP2 CRTAC1 SLC6A14	1.06e-04	185	59	4	563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FCRL3 PLAAT4 FSD1 SESN1	1.06e-04	185	59	4	593eceb3dfcc662c892a840ba29ab687c6886c01
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFRP5 LRP2 CRTAC1 SLC6A14	1.06e-04	185	59	4	7460387f48f33674330bd53b759681b264228f5a
ToppCell	facs-Skin-Anagen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRYBG2 CLCA2 NUP93 TMPRSS11F	1.08e-04	186	59	4	9a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRSS12 CHRDL1 PARD3B CRTAC1	1.12e-04	188	59	4	8268574584e5fb869a6cb8bbd7135cd7454a6a25
ToppCell	IPF-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	SFRP5 LRP2 CRTAC1 SLC6A14	1.12e-04	188	59	4	5f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRSS12 CHRDL1 PARD3B CRTAC1	1.15e-04	189	59	4	222e67d3fd106c43b0cae6538dddeaa7be1f759f
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 PRSS12 BTBD17 CHRDL1	1.15e-04	189	59	4	0493f7b79127c207fd7ade778ef4810500495d7e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRSS12 CHRDL1 PARD3B CRTAC1	1.17e-04	190	59	4	59720dfe9de1b980807644536c919d2a02ba69dd
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SERPINE2 SFRP5 BTBD17 CHRDL1	1.22e-04	192	59	4	d2161842a38146261847fc9061ba9322e0f087e0
ToppCell	droplet-Heart-nan-18m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ASB2 MYO18B ATP2A2	1.22e-04	192	59	4	0bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MOSPD2 LRP2 ANKRD18A SEC14L5	1.22e-04	192	59	4	3ce5dbde41aeb73d49f2c7991d34682f0827fa5a
ToppCell	droplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ASB2 MYO18B ATP2A2	1.22e-04	192	59	4	d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	SLC41A2 CNTN4 ARHGAP40 PRSS12	1.24e-04	193	59	4	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FCRL3 PLAAT4 FSD1 SESN1	1.27e-04	194	59	4	5afe7f48d3383f3dac18765f97999c8b6936dc1b
ToppCell	10x5'v1-week_12-13-Lymphocytic_NK-T_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FCRL3 PLAAT4 FSD1 SESN1	1.27e-04	194	59	4	ec7e0ca6c9a2f63938e06ee771da09eff14fc3b5
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Club\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SLC41A2 ARHGAP40 LRP2 CRTAC1	1.32e-04	196	59	4	4e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SERPINE2 SFRP5 CHRDL1 CRTAC1	1.32e-04	196	59	4	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ASB2 MYO18B ATP2A2	1.32e-04	196	59	4	a582130862bee76c0385156a333bfdfc75cf218b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ASB2 MYO18B ATP2A2	1.32e-04	196	59	4	fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	PRSS12 CHRDL1 RENBP TRAK1	1.32e-04	196	59	4	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SERPINE2 SFRP5 CHRDL1 CRTAC1	1.32e-04	196	59	4	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	POLR2F LRP2 ANKRD18A SEC14L5	1.32e-04	196	59	4	37a5f9f3988778655580bd0383811bb4930c1551
ToppCell	AT2_cells-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	SFRP5 LRP2 CRTAC1 SLC6A14	1.34e-04	197	59	4	fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CNTN4 SERPINE2 POLR2F CRTAC1	1.34e-04	197	59	4	b8dc192fc98428bbb701cc2ea57fc8ad93397785
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTN4 GDF7 ARHGAP40 PRSS12	1.37e-04	198	59	4	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SERPINE2 ANKRD10 CHRDL1 CRTAC1	1.37e-04	198	59	4	02d0d8a212e09c0962ab1dae6a885d26d357f66a
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CNTN4 GDF7 ARHGAP40 PRSS12	1.37e-04	198	59	4	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-Neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SERPINE2 PRSS12 CHRDL1 NUP93	1.37e-04	198	59	4	90ebefc9ba8dc2a81471e5693384f5ce56f06298
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SFRP5 SH3PXD2A CHRDL1 PARD3B	1.40e-04	199	59	4	a13f4b8a039304e685464cc8879659824cad5a3e
ToppCell	Biopsy_IPF-Epithelial-AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	SFRP5 LRP2 CRTAC1 SLC6A14	1.40e-04	199	59	4	c841d475703d3489161fb7904526bd7563d5fb0f
ToppCell	Neuronal-Inhibitory-iA-iA_2(LAMP5)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	PRSS12 CHRDL1 PARD3B CRTAC1	1.42e-04	200	59	4	e90155498397524b812c46f2412320230b445bb6
Disease	Klippel-Feil syndrome	GDF6 MYO18B	2.35e-05	4	59	2	cv:C0022738
Disease	Fc receptor-like protein 4 measurement	SERPINE2 FCRL3	2.35e-05	4	59	2	EFO_0801599
Disease	cleft lip (is_implicated_in)	GDF6 POMT1	4.06e-04	15	59	2	DOID:9296 (is_implicated_in)
Disease	left atrial function	GDF6 MYO18B	8.05e-04	21	59	2	EFO_0004294
Disease	Child Development Disorders, Specific	CNTN4 LRP2	1.54e-03	29	59	2	C0085997
Disease	Child Development Deviations	CNTN4 LRP2	1.54e-03	29	59	2	C0085996
Disease	Developmental Disabilities	CNTN4 LRP2	1.65e-03	30	59	2	C0008073
Disease	esophageal carcinoma	CSNK1A1 ATP2A2	1.65e-03	30	59	2	EFO_0002916
Disease	Adult T-Cell Lymphoma/Leukemia	CSNK1A1 CSNK2A1	1.76e-03	31	59	2	C0023493
Disease	pack-years measurement, systolic blood pressure	CNTN4 LRP2	2.12e-03	34	59	2	EFO_0006335, EFO_0006526
Disease	Craniofacial Abnormalities	CNTN4 CSNK1A1 LRP2	3.79e-03	156	59	3	C0376634

Protein segments in the cluster

Peptide	Gene	Start	Entry
GRELAHELGYPWVEY	ANKLE2	566	Q86XL3
IDDGEVLYLVHYYGW	ARID4A	601	P29374
QEYAGPGYDIRDWEL	ANKRD18A	21	Q8IVF6
RPSWVEDIGDNLYYG	ANKRD10	361	Q9NXR5
KEGWLPLHEAAYYGQ	ASB2	136	Q96Q27
GWYHYAVGTGDEALR	BTBD17	171	A6NE02
QEYAGRGYHIRDWEL	ANKRD18B	21	A2A2Z9
GRIQGYEVKYWRHED	CNTN4	831	Q8IWV2
EDQGVRVTWYHLYDG	AADACL4	361	Q5VUY2
LHEVYEPDWYGREDV	AMPH	81	P49418
QEYAGRGYHIRDWEL	ANKRD19P	21	Q9H560
GEVEGHPVWALIYYC	NUP93	311	Q8N1F7
QDQAVHLWRYEGGYP	NIPSNAP2	121	O75323
HLWRYEGGYPALTEV	NIPSNAP2	126	O75323
WGPARAEEEHGVYVY	PAN2	836	Q504Q3
GPGYWVKIHHLEYTD	PARD3B	41	Q8TEW8
RDPEYGEWFGYLSRE	RENBP	361	P51606
HEGRLEVYYRGQWGT	PRSS12	396	P56730
IDGGEHYWEVRYEPD	FSD1	351	Q9BTV5
YGWGDPIRLRHLYTS	FGF19	36	O95750
VYIHGLYLDGARWDR	DNAH12	2991	Q6ZR08
DLWYNFIELPYHGES	SERPINE2	236	P07093
PRGLAVDRSDGYVYW	LRP2	2236	P98164
AHLPDWGYRQLEIVG	POMT1	481	Q9Y6A1
YPWGREIYTLEGVVD	FBXO38	1081	Q6PIJ6
HLGYPWLFLARYVEG	GAL3ST2	91	Q9H3Q3
LDSIAYGHRLIPYDW	ERVK-10	336	P87889
LDSIAYGHRLIPYDW	ERVK-24	336	P63145
DPVHGGSWIRGAIYY	ATP2A2	281	P16615
LRLIDWGLAEFYHPG	CSNK2A3	171	Q8NEV1
VGERWHPYLEPYGLV	CHRDL1	46	Q9BU40
GHQYLLEEGEYPDWS	CRYBG2	1226	Q8N1P7
LRLIDWGLAEFYHPG	CSNK2A1	171	P68400
RGSFPILYWFYHEDD	FCRL3	501	Q96P31
VDIVYGNWNGPHRLY	CRTAC1	306	Q9NQ79
LWPEVQKLYGHGYEI	ELP2	556	Q6IA86
GGWHYQDIDGRPLYI	SEC14L5	316	O43304
AEEPWVHLHYYGLRD	POLR3E	201	Q9NVU0
WIIAPLEYEAYHCEG	GDF6	371	Q6KF10
PRWLLEIGVIYLHGY	MOSPD2	86	Q8NHP6
PYMYTRGRELEHWDE	SYT15	386	Q9BQS2
VVPYGVDLHYWGQEL	UVSSA	501	Q2YD98
WEDHGYSLVNRLYPD	SESN1	356	Q9Y6P5
EYDYYGWQAEPLHGR	SFRP5	31	Q5T4F7
VGIPHIRWYGQEKDY	CSNK1A1	71	P48729
GDLIEIFRLGYEHWA	PLAAT4	11	Q9UL19
IFRLGYEHWALYIGD	PLAAT4	16	Q9UL19
WIIAPLDYEAYHCEG	GDF7	366	Q7Z4P5
ILGWIPEGKYYLDHS	SLC41A2	261	Q96JW4
IRRYLPDGSYEDWGV	POLR2F	106	P61218
VIVTDWYGAHGDDPY	CLCA2	111	Q9UQC9
DRWGHSGYKELYPEE	NKAPD1	106	Q6ZUT1
IYGYDHDDWLHTPLI	TRAK1	61	Q9UPV9
LGGDAWRLYEYITRH	TOP3B	401	O95985
GPLVYDNHDIWYIVG	TMPRSS11F	391	Q6ZWK6
AYLLDLYRANPHGEW	ARHGAP40	601	Q5TG30
RAIQWGEDGRPFHYL	MRPS9	136	P82933
RFGELEGWAPSHYLV	SH3PXD2A	881	Q5TCZ1
REFYAWIREHGPESG	ZSCAN25	96	Q6NSZ9
HVRGDGPWYYYETID	NDUFB5	161	O43674
FHQLGWDPVRYDLTG	MYO18B	1086	Q8IUG5
WGPYLEQHRGERYKD	SLC6A14	606	Q9UN76
EGEDYVLLPAAAWHY	USP11	151	P51784