Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein kinase activity	STK32A CDKL5 FLT4 MAP4K4 TRIM28 CDK13 WNK2	1.00e-04	600	37	7	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	STK32A CDKL5 FLT4 MAP4K4 TRIM28 CDK13 WNK2	2.81e-04	709	37	7	GO:0016773
GeneOntologyMolecularFunction	kinase activity	STK32A CDKL5 FLT4 MAP4K4 TRIM28 CDK13 WNK2	4.41e-04	764	37	7	GO:0016301
GeneOntologyMolecularFunction	protein serine kinase activity	STK32A CDKL5 MAP4K4 CDK13 WNK2	5.22e-04	363	37	5	GO:0106310
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	STK32A CDKL5 MAP4K4 CDK13 WNK2	1.31e-03	446	37	5	GO:0004674
GeneOntologyMolecularFunction	cyclin-dependent protein kinase activity	CDKL5 CDK13	1.41e-03	30	37	2	GO:0097472
GeneOntologyMolecularFunction	cyclin-dependent protein serine/threonine kinase activity	CDKL5 CDK13	1.41e-03	30	37	2	GO:0004693
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	STK32A CDKL5 FLT4 MAP4K4 TRIM28 CDK13 WNK2	1.48e-03	938	37	7	GO:0016772
GeneOntologyMolecularFunction	microtubule binding	MAP9 TUBGCP2 ALMS1 MAP4K4	2.46e-03	308	37	4	GO:0008017
HumanPheno	Bulbous nose	TUBGCP2 TBC1D23 CPT2 SRRM2 CDK13 SMARCAL1	2.01e-05	201	16	6	HP:0000414
Domain	PROTEIN_KINASE_ATP	STK32A CDKL5 FLT4 MAP4K4 CDK13 WNK2	3.02e-04	459	38	6	PS00107
Domain	Prot_kinase_dom	STK32A CDKL5 FLT4 MAP4K4 CDK13 WNK2	4.23e-04	489	38	6	IPR000719
Domain	PROTEIN_KINASE_DOM	STK32A CDKL5 FLT4 MAP4K4 CDK13 WNK2	4.42e-04	493	38	6	PS50011
Domain	Kinase-like_dom	STK32A CDKL5 FLT4 MAP4K4 CDK13 WNK2	7.28e-04	542	38	6	IPR011009
Domain	Ser/Thr_kinase_AS	STK32A CDKL5 MAP4K4 CDK13 WNK2	7.41e-04	357	38	5	IPR008271
Domain	S_TKc	STK32A CDKL5 MAP4K4 CDK13 WNK2	7.60e-04	359	38	5	SM00220
Domain	PROTEIN_KINASE_ST	STK32A CDKL5 MAP4K4 CDK13 WNK2	7.89e-04	362	38	5	PS00108
Domain	Protein_kinase_ATP_BS	STK32A CDKL5 FLT4 MAP4K4 CDK13	9.70e-04	379	38	5	IPR017441
Domain	Pkinase	STK32A CDKL5 MAP4K4 CDK13 WNK2	9.93e-04	381	38	5	PF00069
Domain	FERM_C	PTPN14 FRMD6	1.27e-03	26	38	2	PF09380
Domain	FERM_C	PTPN14 FRMD6	1.37e-03	27	38	2	SM01196
Domain	FERM_PH-like_C	PTPN14 FRMD6	1.37e-03	27	38	2	IPR018980
Domain	FERM_N	PTPN14 FRMD6	2.05e-03	33	38	2	IPR018979
Domain	FERM_N	PTPN14 FRMD6	2.05e-03	33	38	2	PF09379
Domain	PTPc	PTPN14 PTPRN2	2.43e-03	36	38	2	SM00194
Domain	TYR_PHOSPHATASE_PTP	PTPN14 PTPRN2	2.85e-03	39	38	2	PS50055
Domain	PTPase_domain	PTPN14 PTPRN2	3.14e-03	41	38	2	IPR000242
Domain	Y_phosphatase	PTPN14 PTPRN2	3.14e-03	41	38	2	PF00102
Domain	FERM_M	PTPN14 FRMD6	3.94e-03	46	38	2	PF00373
Domain	FERM_central	PTPN14 FRMD6	4.46e-03	49	38	2	IPR019748
Domain	FERM_domain	PTPN14 FRMD6	4.46e-03	49	38	2	IPR000299
Domain	-	PTPN14 FRMD6	4.46e-03	49	38	2	1.20.80.10
Domain	FERM_1	PTPN14 FRMD6	4.64e-03	50	38	2	PS00660
Domain	FERM_2	PTPN14 FRMD6	4.64e-03	50	38	2	PS00661
Domain	Band_41_domain	PTPN14 FRMD6	4.64e-03	50	38	2	IPR019749
Domain	B41	PTPN14 FRMD6	4.64e-03	50	38	2	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	PTPN14 FRMD6	4.64e-03	50	38	2	IPR014352
Domain	FERM_3	PTPN14 FRMD6	4.64e-03	50	38	2	PS50057
Domain	PTPc_motif	PTPN14 PTPRN2	6.41e-03	59	38	2	SM00404
Domain	Tyr_Pase_cat	PTPN14 PTPRN2	6.41e-03	59	38	2	IPR003595
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	SHANK1 TDRD3 FRY TUBGCP2 RFC1 WNK2 RYR2	6.17e-07	462	38	7	31138677
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	PPHLN1 MCMBP RFC1 SRRM2 TRIM28 CDK13 ZC3HAV1	1.09e-06	503	38	7	16964243
Pubmed	Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humans.	FLT4 PTPN14	1.16e-06	2	38	2	20826270
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM15B RFC1 SRRM2 MAP4K4 TRIM28 CDK13 ESF1 ZC3HAV1	1.57e-06	774	38	8	15302935
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RBM15B TDRD3 PPHLN1 SRRM2 TRIM28 CDK13 ESF1 ZC3HAV1	2.14e-06	807	38	8	22681889
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	TDRD3 MCMBP GIT2 PTPN14 TUBGCP2 MORC4 ALMS1	3.05e-06	588	38	7	38580884
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	GIT2 SRRM2 MAP4K4 TRIM28 CDK13 ZC3HAV1	4.57e-06	401	38	6	25852190
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ALMS1 SRRM2 PTPRN2 PDZD2	5.15e-06	104	38	4	9205841
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	RFC1 MORC4 PTPRN2 FDFT1 SMARCAL1 RYR2 ESF1	5.21e-06	638	38	7	31182584
Pubmed	Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands.	FLT4 CDK13	6.96e-06	4	38	2	28991257
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	TDRD3 GIT2 PTPN14 TUBGCP2 MAP4K4	7.77e-06	251	38	5	29778605
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 TDRD3 FRY GIT2 PTPRN2 MAP4K4 TRIM28 WNK2	7.85e-06	963	38	8	28671696
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBM15B TDRD3 RFC1 TRIM28 CDK13 ESF1 ZC3HAV1	1.61e-05	759	38	7	35915203
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	FGA TDRD3 PTPN14 ALMS1 CPT2 SRRM2 CDK13 ESF1 ZC3HAV1	2.59e-05	1496	38	9	32877691
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	PTPN14 ALMS1 MAP4K4 TRIM28 ESF1 ZC3HAV1	2.71e-05	549	38	6	38280479
Pubmed	Genetics of lymphatic anomalies.	FLT4 PTPN14	3.24e-05	8	38	2	24590274
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MCMBP PTPN14 ALMS1 FRMD6 SRRM2 MAP4K4 ZC3HAV1	3.59e-05	861	38	7	36931259
Pubmed	Regulation of error-prone translesion synthesis by Spartan/C1orf124.	RFC1 TRIM28 ZC3HAV1	3.75e-05	59	38	3	23254330
Pubmed	A negative genetic interaction map in isogenic cancer cell lines reveals cancer cell vulnerabilities.	STK32A RFC1 ALMS1 NAB1	4.46e-05	180	38	4	24104479
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RBM15B PPHLN1 PTPN14 TUBGCP2 RFC1 TRIM28 ESF1 ZC3HAV1	5.30e-05	1257	38	8	36526897
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	CDKL5 PPHLN1 GIT2 TUBGCP2 ZNF639	5.52e-05	378	38	5	34315543
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	MAP9 FRY TUBGCP2 SRRM2 TRIM28 ZC3HAV1	6.29e-05	639	38	6	23443559
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	RBM15B SRRM2 CDK13 RYR2	6.34e-05	197	38	4	20811636
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	PPHLN1 PTPRN2 MAP4K4 TRIM28 CDK13 FDFT1 SMARCAL1 ESF1	7.74e-05	1327	38	8	32694731
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	TDRD3 PTPN14 RFC1 TRIM28 CDK13 ZC3HAV1	8.71e-05	678	38	6	30209976
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CDKL5 PPHLN1 FRY ALMS1 SRRM2 CDK13	9.98e-05	695	38	6	23602568
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	PPHLN1 MCMBP RFC1 TRIM28 CDK13 SMARCAL1 ESF1	1.00e-04	1014	38	7	32416067
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	TDRD3 MCMBP PTPN14 SRRM2 PTPRN2 FDFT1 ESF1	1.24e-04	1049	38	7	27880917
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RBM15B MCMBP RFC1 SRRM2 MAP4K4 TRIM28 ESF1 ZC3HAV1	1.27e-04	1425	38	8	30948266
Pubmed	RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.	RFC1 SMARCAL1	1.38e-04	16	38	2	26474068
Pubmed	Tissue distribution and subcellular localization of the family of Kidney Ankyrin Repeat Domain (KANK) proteins.	KANK4 FLT4	1.38e-04	16	38	2	33253712
Pubmed	TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.	RFC1 TRIM28	1.38e-04	16	38	2	31823782
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	RFC1 MORC4 ALMS1 TRIM28 CDK13	1.52e-04	469	38	5	27634302
Pubmed	A genome wide association study identifies common variants associated with lipid levels in the Chinese population.	PTPN14 RYR2	1.56e-04	17	38	2	24386095
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	GIT2 PTPN14 FRMD6 SRRM2	1.71e-04	255	38	4	15324660
Pubmed	The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.	RFC1 TRIM28 CDK13 ESF1 ZC3HAV1	1.74e-04	483	38	5	36912080
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	PTPN14 ALMS1 MAP4K4 ZC3HAV1	1.93e-04	263	38	4	34702444
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	PPHLN1 GIT2 ALMS1 FDFT1 PEG3	1.99e-04	497	38	5	23414517
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	MCMBP PTPN14 FRMD6 SRRM2	2.13e-04	270	38	4	24366813
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	RFC1 MORC4 CPT2 SRRM2 TRIM28 ESF1 ZC3HAV1	2.17e-04	1149	38	7	35446349
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RBM15B PPHLN1 RFC1 SRRM2 TRIM28 ZC3HAV1	2.91e-04	847	38	6	35850772
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PTPN14 TUBGCP2 TBC1D23 ALMS1 MAP4K4 ZC3HAV1	3.02e-04	853	38	6	28718761
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MCMBP PTPN14 RFC1 SRRM2 TRIM28 ESF1 ZC3HAV1	3.57e-04	1247	38	7	27684187
Pubmed	STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.	RFC1 SRRM2 TRIM28 ZC3HAV1	3.87e-04	316	38	4	31665637
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ALMS1 PTPRN2 PDZD2	3.91e-04	130	38	3	12421765
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	RFC1 SRRM2 TRIM28 ZC3HAV1	3.91e-04	317	38	4	30997501
Pubmed	TRAIP regulates replication fork recovery and progression via PCNA.	MCMBP RFC1	4.01e-04	27	38	2	27462463
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	GIT2 SRRM2 CDK13	4.18e-04	133	38	3	15144186
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RBM15B PPHLN1 RFC1 SRRM2 TRIM28 CDK13 ZC3HAV1	4.46e-04	1294	38	7	30804502
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	TDRD3 RFC1 ALMS1 TRIM28 ESF1 ZC3HAV1	4.89e-04	934	38	6	33916271
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	RBM15B RFC1 SRRM2 TRIM28 ZC3HAV1	4.89e-04	605	38	5	28977666
Pubmed	Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.	RFC1 ZC3HAV1	4.96e-04	30	38	2	16449650
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	PTPN14 RFC1 SRRM2 TRIM28 ZC3HAV1	5.27e-04	615	38	5	31048545
Pubmed	Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control.	SRRM2 ZC3HAV1	5.30e-04	31	38	2	25817432
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM15B PPHLN1 RFC1 SRRM2 TRIM28 ESF1	5.47e-04	954	38	6	36373674
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	RFC1 SRRM2 TRIM28 SMARCAL1 ZC3HAV1	5.71e-04	626	38	5	33644029
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	FLT4 PTPN14 RFC1 SRRM2 TRIM28 ZC3HAV1	6.00e-04	971	38	6	33306668
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	MCMBP PTPN14 SRRM2 PTPRN2 TRIM28 ZC3HAV1	6.10e-04	974	38	6	28675297
Pubmed	Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.	CDKL5 PPHLN1 SRRM2 ZC3HAV1	6.38e-04	361	38	4	30344098
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RBM15B PPHLN1 SRRM2 CDK13	6.38e-04	361	38	4	26167880
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	PPHLN1 MCMBP RFC1 SRRM2 TRIM28 ESF1	6.60e-04	989	38	6	36424410
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	RFC1 SRRM2 TRIM28 CDK13 ZC3HAV1	7.00e-04	655	38	5	35819319
Pubmed	An investigation into the human serum "interactome".	FGA RYR2 PEG3	7.42e-04	162	38	3	15174051
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PTPN14 FRMD6 MAP4K4 ZC3HAV1	7.50e-04	377	38	4	38117590
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	SRRM2 MAP4K4 TRIM28 CDK13 ZC3HAV1	7.50e-04	665	38	5	30457570
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	PPHLN1 ALMS1 SRRM2 MAP4K4 CDK13	7.75e-04	670	38	5	22990118
Pubmed	Association of gene polymorphisms with chronic kidney disease in Japanese individuals.	PTPRN2 WNK2	8.40e-04	39	38	2	19724895
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	PPHLN1 PTPN14 MAP4K4 CDK13	9.25e-04	399	38	4	37536630
Pubmed	TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia.	TUBGCP2 TRIM28	9.28e-04	41	38	2	19786618
Pubmed	URI Regulates KAP1 Phosphorylation and Transcriptional Repression via PP2A Phosphatase in Prostate Cancer Cells.	TRIM28 ZC3HAV1	9.74e-04	42	38	2	27780869
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	TUBGCP2 TRIM28 FDFT1 ZC3HAV1	1.01e-03	408	38	4	33766124
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MCMBP PTPN14 SRRM2 MAP4K4 FDFT1 ESF1 ZC3HAV1	1.01e-03	1487	38	7	33957083
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	RBM15B PPHLN1 RFC1 SRRM2 ZC3HAV1	1.02e-03	713	38	5	29802200
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RBM15B TDRD3 ECT2L PPHLN1 CDK13 ESF1 ZC3HAV1	1.05e-03	1497	38	7	31527615
Pubmed	Identification of APBB1 as a substrate for anaplastic lymphoma kinase.	MAP4K4 ZC3HAV1	1.07e-03	44	38	2	39115278
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	TRIM28 ZC3HAV1	1.07e-03	44	38	2	26471122
Interaction	ANKRD50 interactions	RBM15B MAP9 PPHLN1 PTPN14 ESF1	1.76e-06	108	38	5	int:ANKRD50
Interaction	JPH3 interactions	RBM15B MAP9 RYR2 ESF1	3.42e-06	55	38	4	int:JPH3
Interaction	YWHAH interactions	RBM15B PPHLN1 MCMBP GIT2 PTPN14 ALMS1 FRMD6 SRRM2 MAP4K4 WNK2 ZC3HAV1	3.82e-06	1102	38	11	int:YWHAH
Interaction	EZH1 interactions	RBM15B MAP9 PPHLN1 ESF1	2.67e-05	92	38	4	int:EZH1
Interaction	LINC02910 interactions	RBM15B MAP9 PPHLN1 ESF1	3.02e-05	95	38	4	int:LINC02910
Interaction	SNX27 interactions	FGA CDKL5 PPHLN1 GIT2 TUBGCP2 TRIM28 ZNF639	4.03e-05	509	38	7	int:SNX27
Interaction	ANAPC15 interactions	RBM15B MAP9 PPHLN1 ESF1	9.69e-05	128	38	4	int:ANAPC15
Interaction	HAX1 interactions	ECT2L FLT4 PTPN14 TUBGCP2 ALMS1 TRIM28	1.00e-04	404	38	6	int:HAX1
Interaction	AP3S1 interactions	FLT4 MAP4K4 TRIM28 ESF1	1.41e-04	141	38	4	int:AP3S1
Interaction	COPZ1 interactions	FLT4 RFC1 TRIM28 ZC3HAV1	1.49e-04	143	38	4	int:COPZ1
Interaction	CFAP141 interactions	RBM15B PPHLN1 ESF1	1.52e-04	55	38	3	int:CFAP141
Interaction	LATS1 interactions	TDRD3 PPHLN1 PTPN14 ALMS1 SRRM2 MAP4K4	1.60e-04	440	38	6	int:LATS1
Cytoband	19q13.4	TRIM28 PEG3	1.97e-03	79	38	2	19q13.4
GeneFamily	Cyclin dependent kinases	CDKL5 CDK13	4.51e-04	26	22	2	496
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTPN14 FRMD6	1.67e-03	50	22	2	1293
GeneFamily	Ankyrin repeat domain containing	SHANK1 KANK4 GIT2	3.02e-03	242	22	3	403
Coexpression	GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN	PPHLN1 MCMBP GIT2 CDK13 NAB1	1.01e-05	200	38	5	M4876
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	SHANK1 FGA FRY PEG3 PDZD2	3.11e-07	168	38	5	d02eba7ece17edcdd47fd6b784c93910ce61090f
ToppCell	Control-Endothelial-Epi-like-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MORC4 FRMD6 PTPRN2 CDK13	9.60e-06	157	38	4	2c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCell	Control-Endothelial-Epi-like\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MORC4 FRMD6 PTPRN2 CDK13	9.60e-06	157	38	4	4d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCell	Endothelial-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	FLT4 PTPN14 FRMD6 RYR2	1.22e-05	167	38	4	6a03d16165e0b003092c39972928981abd4a75aa
ToppCell	10x5'-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	SHANK1 FRY PEG3 PDZD2	1.31e-05	170	38	4	97df5ffb328196c46568975d2d97722bcc753bf5
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A FRMD6 WNK2 PEG3	1.64e-05	180	38	4	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SHANK1 FRMD6 RYR2 PEG3	1.75e-05	183	38	4	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	STK32A CDKL5 PTPN14 MORC4	1.75e-05	183	38	4	351d575339038bd4a66f408da518c567444208e8
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ECT2L WNK2 RYR2 PDZD2	2.03e-05	190	38	4	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ECT2L WNK2 RYR2 PDZD2	2.08e-05	191	38	4	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	STK32A FRY PEG3 PDZD2	2.08e-05	191	38	4	f9a46956778a8773d6656340ecf5d218376d79c2
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	FRY WNK2 RYR2 PDZD2	2.21e-05	194	38	4	c3535f7cc0076653c72db582047cff053c322397
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRY PTPRN2 RYR2 PEG3	2.39e-05	198	38	4	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRY PTPRN2 RYR2 PEG3	2.39e-05	198	38	4	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRY PTPRN2 RYR2 PEG3	2.39e-05	198	38	4	0ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRY PTPRN2 RYR2 PEG3	2.39e-05	198	38	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KANK4 PTPN14 PDZD2	2.20e-04	138	38	3	a88c3ae56b0af60f6e87cabade4f21e2bbb336f2
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tregs\|GI_large-bowel / Manually curated celltypes from each tissue	FLT4 PTPRN2 NAB1	3.52e-04	162	38	3	9a5e65c45f73a6a685b8362aa2e6aea77181caa3
ToppCell	Endothelial-B-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	FLT4 PTPN14 FRMD6	3.72e-04	165	38	3	b6893882472aeb0d18e26f47eaec9d53688afcde
ToppCell	droplet-Heart-nan-24m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KANK4 FLT4 PDZD2	3.85e-04	167	38	3	a35ace2c722936d2a3e1f0826e5b6ec6b1340d2b
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 PTPN14 PEG3	3.92e-04	168	38	3	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLT4 PTPN14 PEG3	3.92e-04	168	38	3	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4\|TCGA-Liver / Sample_Type by Project: Shred V9	MAP4K4 WNK2 PEG3	3.99e-04	169	38	3	0a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY WNK2 RYR2	4.06e-04	170	38	3	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGA FLT4 PTPN14	4.20e-04	172	38	3	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGA FLT4 PTPN14	4.20e-04	172	38	3	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	Endothelial-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	FLT4 PTPN14 FRMD6	4.20e-04	172	38	3	8a527dff06d841a86c7eb04a1dd9630787294da4
ToppCell	wk_15-18-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	STK32A PTPN14 PEG3	4.56e-04	177	38	3	b01d7a6a78169962123ddfb0bb588f51d138ad02
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 PTPN14 FRMD6	4.64e-04	178	38	3	ad3de3e03a401dac64431a541899445262246347
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A PTPRN2 PEG3	4.64e-04	178	38	3	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBM15B STK32A PTPN14	4.79e-04	180	38	3	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBM15B STK32A PTPN14	4.79e-04	180	38	3	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	MS-Treg-naive_CD4\|MS / Condition, Cell_class and T cell subcluster	MAP9 PTPN14 MORC4	4.79e-04	180	38	3	7ca083616926d98420fa11a6e5ebc981623f79ac
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RBM15B STK32A PTPN14	4.79e-04	180	38	3	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGA STK32A WNK2	4.95e-04	182	38	3	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A PTPN14 MAP4K4	5.03e-04	183	38	3	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 PTPN14 FRMD6	5.03e-04	183	38	3	4d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell	(6)_Endothelial-F_(Lymphatics)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	FLT4 PTPN14 FRMD6	5.11e-04	184	38	3	03ea613e00b45c81b752c14505a0538d698f551e
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	FRY RYR2 PDZD2	5.11e-04	184	38	3	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FRY FLT4 PTPN14	5.11e-04	184	38	3	7294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY WNK2 RYR2	5.19e-04	185	38	3	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKL5 FLT4 PTPN14	5.19e-04	185	38	3	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM15B FGA MAP4K4	5.19e-04	185	38	3	a2cae8c657e4f4d121476798e424876f7e247973
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	FRY RYR2 PDZD2	5.19e-04	185	38	3	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	FLT4 PTPN14 FRMD6	5.19e-04	185	38	3	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	facs-Thymus-nan-3m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM15B FGA MAP4K4	5.19e-04	185	38	3	d50406a9a5b8d75110ba5985741aa2293950c543
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	STK32A FDFT1 WNK2	5.19e-04	185	38	3	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	FLT4 PTPN14 FRMD6	5.19e-04	185	38	3	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDKL5 FLT4 PTPN14	5.19e-04	185	38	3	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 PTPN14 FRMD6	5.27e-04	186	38	3	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SHANK1 PTPRN2 PEG3	5.27e-04	186	38	3	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 PTPN14 FRMD6	5.27e-04	186	38	3	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KANK4 STK32A WNK2	5.36e-04	187	38	3	16e55d802fc4e71878305e61ad03806aabd59537
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	FLT4 PTPN14 FRMD6	5.36e-04	187	38	3	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGA KANK4 STK32A	5.44e-04	188	38	3	3b8b9161f0fdcbde302ce5b4c0bc874628211109
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ECT2L FLT4 PTPN14	5.44e-04	188	38	3	524a12f433c7b6f33fad36c0716afa06cd3235e9
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGA KANK4 STK32A	5.44e-04	188	38	3	c2101ded71fb16b8ddbc1f883911b1ed2a533ffc
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	FLT4 PTPN14 FRMD6	5.44e-04	188	38	3	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	5'-Adult-Distal_Rectal-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ECT2L FLT4 PTPN14	5.44e-04	188	38	3	d2610b81b3c7f22977b5e2137b1f61410fc4ef16
ToppCell	Endothelial-B\|World / lung cells shred on cell class, cell subclass, sample id	FLT4 PTPN14 FRMD6	5.44e-04	188	38	3	5959a88728812a5f4cbfa54eddc7a73ccbaa2f68
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 PTPN14 FRMD6	5.44e-04	188	38	3	2db80767903703e7e0a1a37c598f7877a909ee94
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 PTPN14 FRMD6	5.44e-04	188	38	3	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 PTPN14 FRMD6	5.44e-04	188	38	3	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	facs-Heart-RA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A WNK2 RYR2	5.52e-04	189	38	3	e4efbb0733b382f4c855f6653dcddf36e0f8df28
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRY WNK2 RYR2	5.52e-04	189	38	3	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRY WNK2 RYR2	5.52e-04	189	38	3	2cfb4d12f75678d1619f4743838a0e954bd57761
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPHLN1 FRY FRMD6	5.52e-04	189	38	3	09dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	FRY WNK2 RYR2	5.52e-04	189	38	3	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	WNK2 RYR2 PDZD2	5.52e-04	189	38	3	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FRY WNK2 RYR2	5.52e-04	189	38	3	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	STK32A PTPN14 PDZD2	5.52e-04	189	38	3	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FRY WNK2 RYR2	5.52e-04	189	38	3	127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	FLT4 PTPN14 FRMD6	5.61e-04	190	38	3	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KANK4 FRY FRMD6	5.61e-04	190	38	3	70c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FRY RYR2 PDZD2	5.61e-04	190	38	3	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLT4 PTPN14 FRMD6	5.61e-04	190	38	3	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	WNK2 RYR2 PDZD2	5.61e-04	190	38	3	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A PTPRN2 PEG3	5.69e-04	191	38	3	f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	STK32A FRY PEG3	5.69e-04	191	38	3	273c4a757292a9301de0eaeacdec91c9866be229
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 PTPRN2 PEG3	5.69e-04	191	38	3	fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCell	facs-Pancreas\|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A PTPRN2 PEG3	5.69e-04	191	38	3	d48e5f67d384226add7d7fb2a124954136e09a82
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD6 SRRM2 PEG3	5.69e-04	191	38	3	7d1595e616f6f111fc2f5bc1b179c5d67d624cc9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRY WNK2 RYR2	5.78e-04	192	38	3	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A PTPRN2 PEG3	5.78e-04	192	38	3	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRY WNK2 RYR2	5.78e-04	192	38	3	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	droplet-Pancreas-Endocrine-18m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 PTPRN2 PEG3	5.78e-04	192	38	3	4510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 PTPRN2 PEG3	5.78e-04	192	38	3	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	FRY WNK2 RYR2	5.78e-04	192	38	3	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FRY RYR2 PDZD2	5.78e-04	192	38	3	5000440dc1ed17e7474d340921bdff945646f27e
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 PTPRN2 PEG3	5.78e-04	192	38	3	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SHANK1 FRY PDZD2	5.78e-04	192	38	3	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	LAM-Endothelial-LymEndo\|LAM / Condition, Lineage and Cell class	FLT4 PTPN14 FRMD6	5.87e-04	193	38	3	68eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	MAP9 PTPRN2 PEG3	5.87e-04	193	38	3	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	STK32A PTPN14 PDZD2	5.87e-04	193	38	3	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 PTPN14 FRMD6	5.87e-04	193	38	3	040f6bb42aa41d0921371fdda1cc0912c4fe1930
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FLT4 PTPN14 FRMD6	5.87e-04	193	38	3	e468287c8b30c56d1de65e8347ade233ba6cf584
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMD6 SRRM2 PEG3	5.87e-04	193	38	3	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RBM15B MAP4K4 TRIM28	5.96e-04	194	38	3	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SRRM2 PTPRN2 PEG3	5.96e-04	194	38	3	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SRRM2 MAP4K4 CDK13	5.96e-04	194	38	3	ff661419b697aef51a53fdeac8d37d870d65f491
Drug	Monocrotaline [315-22-0]; Down 200; 12.2uM; PC3; HT_HG-U133A	TDRD3 MCMBP PTPN14 SRRM2 ZC3HAV1	1.79e-05	196	38	5	7127_DN
Drug	Clemastine fumarate [14976-57-9]; Down 200; 8.6uM; MCF7; HT_HG-U133A	GIT2 ALMS1 CPT2 SRRM2 CDK13	1.79e-05	196	38	5	7485_DN
Drug	Triamcinolone [124-94-7]; Up 200; 10.2uM; PC3; HT_HG-U133A	GIT2 TUBGCP2 MORC4 CDK13 PEG3	1.83e-05	197	38	5	5835_UP
Drug	Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; PC3; HT_HG-U133A	TDRD3 GIT2 SRRM2 RYR2 PEG3	1.83e-05	197	38	5	3763_DN
Drug	Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; PC3; HT_HG-U133A	MCMBP CPT2 SRRM2 CDK13 PEG3	1.93e-05	199	38	5	7284_DN
Drug	Graveoline [485-61-0]; Down 200; 14.4uM; MCF7; HT_HG-U133A	FLT4 GIT2 ALMS1 SMARCAL1 RYR2	1.97e-05	200	38	5	6034_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	MAP9 ALMS1 CPT2 SRRM2 CDK13	1.97e-05	200	38	5	6996_DN
Drug	distearoylphosphatidic acid	FGA FDFT1	7.55e-05	8	38	2	CID000086641
Drug	aluminum phthalocyanine	MAP4K4 PDZD2	1.77e-04	12	38	2	CID000114863
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	TDRD3 SRRM2 CDK13 PEG3	2.17e-04	178	38	4	5086_DN
Drug	Gossypol [303-45-7]; Up 200; 7.8uM; MCF7; HT_HG-U133A	FGA TDRD3 CDK13 PDZD2	2.26e-04	180	38	4	3637_UP
Drug	Lanatoside C [17575-22-3]; Down 200; 4uM; MCF7; HT_HG-U133A	RBM15B TDRD3 ALMS1 CPT2	2.31e-04	181	38	4	6048_DN
Drug	17-AAG; Up 200; 1uM; PC3; HT_HG-U133A	GIT2 ZNF639 PDZD2 ZC3HAV1	2.51e-04	185	38	4	1226_UP
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	TUBGCP2 ALMS1 CPT2 ZC3HAV1	2.56e-04	186	38	4	3279_DN
Drug	perfluorononanoic acid	CPT2 FDFT1 PEG3	2.67e-04	75	38	3	ctd:C584865
Drug	Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	TDRD3 CPT2 SMARCAL1 ZC3HAV1	2.67e-04	188	38	4	3770_DN
Drug	5182598; Down 200; 25uM; MCF7; HT_HG-U133A_EA	TDRD3 GIT2 ALMS1 ZNF639	2.72e-04	189	38	4	976_DN
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; PC3; HT_HG-U133A	RBM15B MCMBP ALMS1 SMARCAL1	2.72e-04	189	38	4	3733_DN
Drug	Azacytidine-5 [320-67-2]; Down 200; 16.4uM; MCF7; HT_HG-U133A	GIT2 RFC1 SRRM2 ZC3HAV1	2.78e-04	190	38	4	3348_DN
Drug	Strophantine octahydrate [11018-89-6]; Down 200; 5.4uM; PC3; HT_HG-U133A	RBM15B PTPRN2 SMARCAL1 ZC3HAV1	2.78e-04	190	38	4	6680_DN
Drug	Digoxin [20830-75-5]; Down 200; 5.2uM; PC3; HT_HG-U133A	RBM15B TDRD3 CPT2 SMARCAL1	2.83e-04	191	38	4	6724_DN
Drug	Piperacetazine [3819-00-9]; Up 200; 9.8uM; MCF7; HT_HG-U133A	PTPRN2 CDK13 ZNF639 ZC3HAV1	2.89e-04	192	38	4	7191_UP
Drug	Fluvastatin sodium salt [93957-55-2]; Down 200; 9.2uM; PC3; HT_HG-U133A	TDRD3 FLT4 PTPRN2 RYR2	2.95e-04	193	38	4	6691_DN
Drug	Pyrithyldione [77-04-3]; Down 200; 24uM; PC3; HT_HG-U133A	TDRD3 GIT2 SRRM2 ZC3HAV1	2.95e-04	193	38	4	7153_DN
Drug	Acenocoumarol [152-72-7]; Down 200; 11.4uM; MCF7; HT_HG-U133A	MCMBP GIT2 CPT2 RYR2	2.95e-04	193	38	4	7232_DN
Drug	(-)-Isoproterenol hydrochloride [5984-95-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A	SHANK1 RYR2 ZNF639 PDZD2	3.01e-04	194	38	4	6833_UP
Drug	Alexidine dihydrochloride [22573-93-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	MCMBP CPT2 SRRM2 RYR2	3.01e-04	194	38	4	4721_DN
Drug	0316684-0000 [391209-55-5]; Down 200; 10uM; PC3; HT_HG-U133A	MCMBP GIT2 CPT2 SRRM2	3.01e-04	194	38	4	7098_DN
Drug	Dichlorphenamide [120-97-8]; Down 200; 13.2uM; MCF7; HT_HG-U133A	GIT2 ALMS1 ZNF639 ZC3HAV1	3.01e-04	194	38	4	3366_DN
Drug	Nifurtimox [23256-30-6]; Down 200; 14uM; MCF7; HT_HG-U133A	GIT2 TUBGCP2 SRRM2 CDK13	3.01e-04	194	38	4	4953_DN
Drug	Mifepristone [84371-65-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A	MAP9 TDRD3 FLT4 TUBGCP2	3.07e-04	195	38	4	3185_DN
Drug	Chlortetracycline hydrochloride [64-72-2]; Up 200; 7.8uM; PC3; HT_HG-U133A	MCMBP SRRM2 PTPRN2 ZNF639	3.07e-04	195	38	4	6761_UP
Drug	haloperidol; Down 200; 10uM; HL60; HT_HG-U133A	TDRD3 GIT2 ALMS1 ZC3HAV1	3.07e-04	195	38	4	1144_DN
Drug	Gliclazide [21187-98-4]; Down 200; 12.4uM; PC3; HT_HG-U133A	TDRD3 TUBGCP2 NAB1 PEG3	3.07e-04	195	38	4	5089_DN
Drug	Risperidone [106266-06-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	FLT4 ALMS1 RYR2 ZNF639	3.07e-04	195	38	4	3508_DN
Drug	Sulfadiazine [68-35-9]; Up 200; 16uM; HL60; HT_HG-U133A	TDRD3 SRRM2 PTPRN2 CDK13	3.13e-04	196	38	4	1852_UP
Drug	Apigenin [520-36-5]; Up 200; 14.8uM; PC3; HT_HG-U133A	SHANK1 FLT4 RYR2 ZNF639	3.13e-04	196	38	4	4578_UP
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	TDRD3 GIT2 CPT2 ZC3HAV1	3.13e-04	196	38	4	6954_DN
Drug	GSK-3 Inhibitor IX; Up 200; 0.5uM; PC3; HT_HG-U133A	MAP9 GIT2 SRRM2 CDK13	3.13e-04	196	38	4	6559_UP
Drug	Famprofazone [22881-35-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A	TDRD3 FLT4 TUBGCP2 SRRM2	3.13e-04	196	38	4	6029_DN
Drug	PHA-00767505E [723337-45-9]; Down 200; 10uM; PC3; HT_HG-U133A	TDRD3 FLT4 PTPRN2 ZC3HAV1	3.13e-04	196	38	4	6591_DN
Drug	6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; MCF7; HT_HG-U133A	GIT2 ALMS1 CDK13 ZC3HAV1	3.13e-04	196	38	4	7346_DN
Drug	Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; PC3; HT_HG-U133A	FRY PTPRN2 CDK13 ZNF639	3.19e-04	197	38	4	4017_UP
Drug	Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; PC3; HT_HG-U133A	GIT2 RFC1 SRRM2 ZC3HAV1	3.19e-04	197	38	4	5887_DN
Drug	Papaverine hydrochloride [61-25-6]; Down 200; 10.6uM; MCF7; HT_HG-U133A	TDRD3 PTPN14 ALMS1 ZC3HAV1	3.19e-04	197	38	4	2747_DN
Drug	Ciprofloxacin hydrochloride [93107-08-5]; Down 200; 10.8uM; PC3; HT_HG-U133A	TDRD3 SRRM2 RYR2 ZC3HAV1	3.19e-04	197	38	4	6700_DN
Drug	Morantel tartrate [26155-31-7]; Down 200; 10.8uM; PC3; HT_HG-U133A	PTPN14 ALMS1 CPT2 SRRM2	3.19e-04	197	38	4	1798_DN
Drug	Rapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A	TDRD3 SRRM2 PTPRN2 NAB1	3.19e-04	197	38	4	2667_UP
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	MCMBP RYR2 NAB1 PEG3	3.19e-04	197	38	4	4666_DN
Drug	Diloxanide furoate [3736-81-0]; Down 200; 12.2uM; MCF7; HT_HG-U133A	PTPN14 TUBGCP2 ALMS1 ZNF639	3.19e-04	197	38	4	5025_DN
Drug	STOCK1N-28457; Up 200; 20uM; PC3; HT_HG-U133A	TDRD3 FLT4 CDK13 ZNF639	3.19e-04	197	38	4	6864_UP
Drug	Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	FLT4 GIT2 TUBGCP2 PTPRN2	3.19e-04	197	38	4	6758_DN
Drug	LY 294002; Down 200; 10uM; HL60; HT_HG-U133A	FRY CPT2 ESF1 ZC3HAV1	3.19e-04	197	38	4	1180_DN
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; PC3; HT_HG-U133A	GIT2 NAB1 ZNF639 ZC3HAV1	3.19e-04	197	38	4	3798_DN
Drug	Cefixime [79350-37-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A	TDRD3 FLT4 SRRM2 CDK13	3.19e-04	197	38	4	3247_UP
Drug	Khellin [82-02-0]; Down 200; 15.4uM; PC3; HT_HG-U133A	CDK13 RYR2 ZNF639 PEG3	3.25e-04	198	38	4	6641_DN
Drug	Streptomycin sulfate [3810-74-0]; Up 200; 2.8uM; MCF7; HT_HG-U133A	FLT4 TUBGCP2 CPT2 ZC3HAV1	3.25e-04	198	38	4	7194_UP
Drug	Acenocoumarol [152-72-7]; Up 200; 11.4uM; MCF7; HT_HG-U133A	MAP9 TDRD3 FRY FLT4	3.25e-04	198	38	4	7232_UP
Drug	Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; PC3; HT_HG-U133A	GIT2 SRRM2 PTPRN2 RYR2	3.25e-04	198	38	4	5786_DN
Drug	PHA-00816795 [212631-79-3]; Up 200; 10uM; PC3; HT_HG-U133A	MCMBP PTPN14 PEG3 ZC3HAV1	3.25e-04	198	38	4	7076_UP
Drug	Ramipril [87333-19-5]; Down 200; 9.6uM; PC3; HT_HG-U133A	GIT2 PTPN14 TUBGCP2 ZC3HAV1	3.25e-04	198	38	4	7144_DN
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A	FLT4 GIT2 RYR2 ZNF639	3.25e-04	198	38	4	5405_DN
Drug	Evoxine [522-11-2]; Down 200; 11.6uM; PC3; HT_HG-U133A	MCMBP CPT2 SRRM2 CDK13	3.25e-04	198	38	4	3681_DN
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; MCF7; HT_HG-U133A	TDRD3 TUBGCP2 ALMS1 RYR2	3.25e-04	198	38	4	1537_DN
Drug	Prednicarbate [73771-04-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A	PTPN14 TUBGCP2 ALMS1 ZC3HAV1	3.25e-04	198	38	4	3542_DN
Drug	Cefaclor [70356-03-5]; Down 200; 10.4uM; PC3; HT_HG-U133A	TDRD3 CPT2 CDK13 ZC3HAV1	3.25e-04	198	38	4	6622_DN
Drug	Harmalol hydrochloride dihydrate [6028-07-5]; Down 200; 14.6uM; MCF7; HT_HG-U133A	TDRD3 GIT2 TUBGCP2 ZNF639	3.25e-04	198	38	4	5495_DN
Drug	Dexamethasone acetate [1177-87-3]; Down 200; 9.2uM; MCF7; HT_HG-U133A	MAP9 TDRD3 GIT2 CPT2	3.25e-04	198	38	4	6271_DN
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	TDRD3 GIT2 RYR2 ZC3HAV1	3.25e-04	198	38	4	6992_UP
Drug	Aminohippuric acid [61-78-9]; Down 200; 20.6uM; PC3; HT_HG-U133A	TDRD3 ALMS1 SRRM2 ZC3HAV1	3.25e-04	198	38	4	6294_DN
Drug	Nifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A	MCMBP GIT2 RFC1 PDZD2	3.25e-04	198	38	4	7303_DN
Drug	Naftopidil dihydrochloride [57149-08-3]; Down 200; 8.6uM; MCF7; HT_HG-U133A	FLT4 GIT2 ALMS1 SMARCAL1	3.31e-04	199	38	4	7331_DN
Drug	PF-00875133-00 [351322-64-0]; Up 200; 10uM; PC3; HT_HG-U133A	TUBGCP2 CPT2 SMARCAL1 PEG3	3.31e-04	199	38	4	5928_UP
Drug	Oxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; PC3; HT_HG-U133A	TDRD3 FLT4 CDK13 PDZD2	3.31e-04	199	38	4	6624_DN
Drug	Harpagoside [19210-12-9]; Down 200; 8uM; PC3; HT_HG-U133A	FLT4 CDK13 RYR2 ZNF639	3.31e-04	199	38	4	6636_DN
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; MCF7; HT_HG-U133A	FLT4 CDK13 RYR2 ZC3HAV1	3.31e-04	199	38	4	2322_DN
Drug	Proadifen hydrochloride [62-68-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A	RBM15B MAP9 TDRD3 CDK13	3.38e-04	200	38	4	7165_DN
Drug	Biomer	FGA FDFT1	4.08e-04	18	38	2	CID003085227
Disease	Metastatic melanoma	STK32A CDKL5 FLT4	4.31e-05	54	37	3	C0278883
Disease	acute pancreatitis	STK32A MORC4	2.31e-04	18	37	2	EFO_1000652
Disease	intellectual disability (is_implicated_in)	CDKL5 CDK13	6.51e-04	30	37	2	DOID:1059 (is_implicated_in)
Disease	Stuttering	FRMD6 RYR2 ESF1	7.67e-04	143	37	3	HP_0025268
Disease	Colorectal Carcinoma	SHANK1 CDKL5 PTPRN2 TRIM28 PEG3	1.74e-03	702	37	5	C0009402
Disease	Cardiomyopathy, Familial Idiopathic	ALMS1 CPT2	1.80e-03	50	37	2	C1449563
Disease	generalised epilepsy	RYR2 NAB1	1.95e-03	52	37	2	EFO_0005917

Protein segments in the cluster

Peptide	Gene	Start	Entry
TLTSTSYSHREKPGT	ALMS1	616	Q8TCU4
EYTDTSNHSSLKRRP	GIT2	491	Q14161
SRGTSHTPFERTSKT	ECT2L	826	Q008S8
SGKSRSRSPYSSRHS	CDK13	406	Q14004
HGRTETIRPASVYTK	CPT2	496	P23786
SDRGRTTHSPYEERS	RBM15B	601	Q8NDT2
TTHSPYEERSRTKGS	RBM15B	606	Q8NDT2
ARPSKHSVGSERRYS	PTPRN2	126	Q92932
RPPHKVTDYSSSSEE	MAP4K4	756	O95819
SKRRTPSTTTSSHYL	MAP9	386	Q49MG5
SRLYPSEAKSHSSES	NAB1	446	Q13506
YHRIPDSDPSSSKTR	FDFT1	346	P37268
YAVDKRGRPISHSTT	ESF1	51	Q9H501
DYSKTRSASETSTPH	PDZD2	1301	O15018
RTPYVTTTVSAHSAK	TUBGCP2	36	Q9BSJ2
QGHSSRSKRSAYPST	PEG3	271	Q9GZU2
TGPEDSYSSSAIHRK	FRMD6	406	Q96NE9
SPGTRREYHTEKLVT	FGA	421	P02671
PQASTSRSEVSYHRK	KANK4	116	Q5T7N3
TSPLYTDGSHTKQTR	ENAM	906	Q9NRM1
ESHEYRPRTSNKSKS	FRY	141	Q5TBA9
SSRSPSYRTKAKSHG	CDKL5	476	O76039
RRTKPDYSTSHSARL	RYR2	1391	Q92736
GSSVSSRSYSPERSK	PPHLN1	146	Q8NEY8
ARVSPSTSYTPSRHK	MCMBP	151	Q9BTE3
STSYTPSRHKRSYED	MCMBP	156	Q9BTE3
RYSHSGSSSPDTKVK	SRRM2	966	Q9UQ35
RTKDTSYPLGSQHSD	TDRD3	386	Q9H7E2
KASRHSTSPSLDSEY	RFC1	1081	P35251
SHDKSSSERSTPPYL	MORC4	611	Q8TE76
RHKYVSGSSPDLVTR	PTPN14	586	Q15678
YIHSSSESVTPRTEG	SMARCAL1	206	Q9NZC9
RPYHIRSSTSSKEIV	STK32A	221	Q8WU08
PDTRVGSREKSLYHS	SHANK1	976	Q9Y566
KTLHPSRYSDSSGIS	ZNF639	11	Q9UID6
TERHVSSSDRVGKPY	TBC1D23	531	Q9NUY8
EKEASSPSIYSRHSR	FLT4	426	P35916
NYKSTSSGHREISSP	ZC3HAV1	446	Q7Z2W4
HPTSERVTYKSSSKP	WNK2	2081	Q9Y3S1
YTKDHTVRSTGPAKS	TRIM28	186	Q13263