Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondisaccharide binding

LGALS9C LGALS9B

7.76e-057392GO:0048030
GeneOntologyMolecularFunctiongalactoside binding

LGALS9C LGALS9B

1.33e-049392GO:0016936
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

AGK PARP4 MYO3A LRRK1 MAP3K7 STK26 MYO3B PTDSS1

3.86e-04938398GO:0016772
GeneOntologyMolecularFunctionprotein serine kinase activity

MYO3A LRRK1 MAP3K7 STK26 MYO3B

6.69e-04363395GO:0106310
GeneOntologyMolecularFunctionoligosaccharide binding

LGALS9C LGALS9B

6.91e-0420392GO:0070492
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC17A7 SLC37A2

9.98e-0424392GO:0005315
GeneOntologyMolecularFunctionmonooxygenase activity

CYP1A1 DBH CMAHP

1.46e-03115393GO:0004497
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO3A DNAH9 MYO3B

1.57e-03118393GO:0003774
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

MYO3A LRRK1 MAP3K7 STK26 MYO3B

1.67e-03446395GO:0004674
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

AGK MYO3A LRRK1 MAP3K7 STK26 MYO3B

2.35e-03709396GO:0016773
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO3A MYO3B

2.50e-0338392GO:0000146
GeneOntologyMolecularFunctionkinase activity

AGK MYO3A LRRK1 MAP3K7 STK26 MYO3B

3.41e-03764396GO:0016301
GeneOntologyBiologicalProcessnegative regulation of natural killer cell degranulation

LGALS9C LGALS9B

1.87e-054372GO:0043322
GeneOntologyCellularComponentfilopodium tip

VIL1 MYO3A MYO3B

7.23e-0620403GO:0032433
GeneOntologyCellularComponentstereocilium

MYO3A USH2A MYO3B

3.12e-0469403GO:0032420
GeneOntologyCellularComponentphotoreceptor inner segment

MYO3A USH2A MYO3B

4.47e-0478403GO:0001917
GeneOntologyCellularComponentstereocilium bundle

MYO3A USH2A MYO3B

4.64e-0479403GO:0032421
GeneOntologyCellularComponentstereocilium tip

MYO3A MYO3B

8.05e-0422402GO:0032426
GeneOntologyCellularComponentcluster of actin-based cell projections

VIL1 MYO3A USH2A MYO3B

8.53e-04223404GO:0098862
GeneOntologyCellularComponentfilopodium

VIL1 MYO3A MYO3B

1.68e-03123403GO:0030175
GeneOntologyCellularComponentcentriolar satellite

DBH DYSF PTPN20

1.88e-03128403GO:0034451
GeneOntologyCellularComponentactin-based cell projection

VIL1 MYO3A USH2A MYO3B

1.92e-03278404GO:0098858
DomainGal-bind_lectin

LGALS9C LGALS9B

3.95e-0415372SM00908
DomainGALECTIN

LGALS9C LGALS9B

3.95e-0415372PS51304
DomainGalectin_CRD

LGALS9C LGALS9B

3.95e-0415372IPR001079
DomainGal-bind_lectin

LGALS9C LGALS9B

3.95e-0415372PF00337
DomainGLECT

LGALS9C LGALS9B

3.95e-0415372SM00276
DomainS_TKc

MYO3A LRRK1 MAP3K7 STK26 MYO3B

6.71e-04359375SM00220
DomainPROTEIN_KINASE_ST

MYO3A LRRK1 MAP3K7 STK26 MYO3B

6.96e-04362375PS00108
Domain-

LGALS9C LGALS9B USH2A

8.74e-04953732.60.120.200
DomainPkinase

MYO3A LRRK1 MAP3K7 STK26 MYO3B

8.77e-04381375PF00069
DomainPlexin_repeat

SEMA6A PLXDC2

1.82e-0332372IPR002165
DomainPSI

SEMA6A PLXDC2

1.82e-0332372PF01437
DomainPROTEIN_KINASE_ATP

MYO3A LRRK1 MAP3K7 STK26 MYO3B

2.00e-03459375PS00107
DomainMYOSIN_MOTOR

MYO3A MYO3B

2.57e-0338372PS51456
DomainMyosin_head

MYO3A MYO3B

2.57e-0338372PF00063
DomainMyosin_head_motor_dom

MYO3A MYO3B

2.57e-0338372IPR001609
DomainMYSc

MYO3A MYO3B

2.57e-0338372SM00242
DomainProt_kinase_dom

MYO3A LRRK1 MAP3K7 STK26 MYO3B

2.63e-03489375IPR000719
DomainPROTEIN_KINASE_DOM

MYO3A LRRK1 MAP3K7 STK26 MYO3B

2.73e-03493375PS50011
DomainPSI

SEMA6A PLXDC2

3.43e-0344372IPR016201
DomainPSI

SEMA6A PLXDC2

3.74e-0346372SM00423
DomainKinase-like_dom

MYO3A LRRK1 MAP3K7 STK26 MYO3B

4.09e-03542375IPR011009
DomainSer/Thr_kinase_AS

MYO3A LRRK1 MAP3K7 MYO3B

5.27e-03357374IPR008271
DomainP-loop_NTPase

MYO3A SLFN11 NOD1 LRRK1 DNAH9 MYO3B

5.99e-03848376IPR027417
DomainProtein_kinase_ATP_BS

MYO3A MAP3K7 STK26 MYO3B

6.50e-03379374IPR017441
DomainIQ

MYO3A MYO3B

8.71e-0371372PF00612
DomainConA-like_dom

LGALS9C LGALS9B USH2A

9.21e-03219373IPR013320
DomainMFS

SLC17A7 SLC37A2

1.02e-0277372IPR011701
DomainMFS_1

SLC17A7 SLC37A2

1.02e-0277372PF07690
DomainIQ

MYO3A MYO3B

1.12e-0281372SM00015
Pubmed

Mouse class III myosins: kinase activity and phosphorylation sites.

MYO3A MYO3B

1.42e-06242221895655
Pubmed

Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions.

MYO3A MYO3B

1.42e-06242227582493
Pubmed

Crystal structure of the galectin-9 N-terminal carbohydrate recognition domain from Mus musculus reveals the basic mechanism of carbohydrate recognition.

LGALS9C LGALS9B

4.27e-06342216990264
Pubmed

Galectin-9 Is Critical for Mucosal Adaptive Immunity through the T Helper 17-IgA Axis.

LGALS9C LGALS9B

4.27e-06342229458010
Pubmed

Structural analysis of the human galectin-9 N-terminal carbohydrate recognition domain reveals unexpected properties that differ from the mouse orthologue.

LGALS9C LGALS9B

4.27e-06342218005988
Pubmed

Galectin-9 ameliorates clinical severity of MRL/lpr lupus-prone mice by inducing plasma cell apoptosis independently of Tim-3.

LGALS9C LGALS9B

4.27e-06342223585851
Pubmed

Galectin-9 ameliorates anti-GBM glomerulonephritis by inhibiting Th1 and Th17 immune responses in mice.

LGALS9C LGALS9B

4.27e-06342224477688
Pubmed

Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation.

LGALS9C LGALS9B

4.27e-06342219776007
Pubmed

A unique role for galectin-9 in angiogenesis and inflammatory arthritis.

LGALS9C LGALS9B

4.27e-06342229433546
Pubmed

Cooperative Interactions of Oligosaccharide and Peptide Moieties of a Glycopeptide Derived from IgE with Galectin-9.

LGALS9C LGALS9B

4.27e-06342226582205
Pubmed

Oncogenic miR-93-5p/Gal-9 axis drives CD8 (+) T-cell inactivation and is a therapeutic target for hepatocellular carcinoma immunotherapy.

LGALS9C LGALS9B

4.27e-06342237105392
Pubmed

Developmental regulation, expression, and apoptotic potential of galectin-9, a beta-galactoside binding lectin.

LGALS9C LGALS9B

4.27e-0634229153289
Pubmed

Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.

LGALS9C LGALS9B

4.27e-06342233316546
Pubmed

Galectin-9 expands unique macrophages exhibiting plasmacytoid dendritic cell-like phenotypes that activate NK cells in tumor-bearing mice.

LGALS9C LGALS9B

4.27e-06342218974023
Pubmed

Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin.

LGALS9C LGALS9B

4.27e-0634229038233
Pubmed

Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion.

LGALS9C LGALS9B

4.27e-06342223144904
Pubmed

Impaired Gal-9 Dysregulates the PBMC-Induced Th1/Th2 Imbalance in Abortion-Prone Matings.

LGALS9C LGALS9B

4.27e-06342229651447
Pubmed

Galectin-9/Tim-3 pathway mediates dopaminergic neurodegeneration in MPTP-induced mouse model of Parkinson's disease.

LGALS9C LGALS9B

4.27e-06342236479526
Pubmed

Protective effect of Galectin-9 in murine model of lung emphysema: Involvement of neutrophil migration and MMP-9 production.

LGALS9C LGALS9B

4.27e-06342228704475
Pubmed

The N- and C-terminal carbohydrate recognition domains of galectin-9 contribute differently to its multiple functions in innate immunity and adaptive immunity.

LGALS9C LGALS9B

4.27e-06342221146220
Pubmed

Profiling Lgals9 splice variant expression at the fetal-maternal interface: implications in normal and pathological human pregnancy.

LGALS9C LGALS9B

4.27e-06342223242525
Pubmed

Galectin-9 in allergic airway inflammation and hyper-responsiveness in mice.

LGALS9C LGALS9B

4.27e-06342219851072
Pubmed

The Role of Galectin-9 as Mediator of Atopic Dermatitis: Effect on Keratinocytes.

LGALS9C LGALS9B

4.27e-06342233923930
Pubmed

Alarmin function of galectin-9 in murine respiratory tularemia.

LGALS9C LGALS9B

4.27e-06342225898318
Pubmed

Amelioration of bleomycin-induced pulmonary fibrosis via TGF-β-induced Smad and non-Smad signaling pathways in galectin-9-deficient mice and fibroblast cells.

LGALS9C LGALS9B

4.27e-06342231937306
Pubmed

Intestinal epithelial cells express galectin-9 in patients with food allergy that plays a critical role in sustaining allergic status in mouse intestine.

LGALS9C LGALS9B

4.27e-06342221426359
Pubmed

Intracellular Galectin-9 Enhances Proximal TCR Signaling and Potentiates Autoimmune Diseases.

LGALS9C LGALS9B

4.27e-06342231969388
Pubmed

Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.

LGALS9C LGALS9B

4.27e-06342223836896
Pubmed

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis.

LGALS9C LGALS9B

4.27e-06342218282810
Pubmed

Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.

LGALS9C LGALS9B

4.27e-06342235241678
Pubmed

Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes.

LGALS9C LGALS9B

4.27e-0634227890611
Pubmed

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner.

LGALS9C LGALS9B

4.27e-06342222341088
Pubmed

Regulation of M1‑type and M2‑type macrophage polarization in RAW264.7 cells by Galectin‑9.

LGALS9C LGALS9B

4.27e-06342228990062
Pubmed

Galectin-9 Is a Novel Regulator of Epithelial Restitution.

LGALS9C LGALS9B

4.27e-06342232380082
Pubmed

Galectin-9 is a suppressor of T and B cells and predicts the immune modulatory potential of mesenchymal stromal cell preparations.

LGALS9C LGALS9B

4.27e-06342224083426
Pubmed

Galectin-9-mediated protection from allo-specific T cells as a mechanism of immune privilege of corneal allografts.

LGALS9C LGALS9B

4.27e-06342223667648
Pubmed

Galectin-9 in synergy with NF-κB inhibition restores immune regulatory capability in dendritic cells of subjects with food allergy.

LGALS9C LGALS9B

4.27e-06342237279535
Pubmed

Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices.

LGALS9C LGALS9B

4.27e-06342218579572
Pubmed

The protective function of galectin-9 in liver ischemia and reperfusion injury in mice.

LGALS9C LGALS9B

4.27e-06342225931247
Pubmed

Possible regulatory role of galectin-9 on Ascaris suum-induced eosinophilic lung inflammation in mice.

LGALS9C LGALS9B

4.27e-06342222627368
Pubmed

Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.

MYO3A MYO3B

4.27e-06342222264607
Pubmed

Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.

LGALS9C LGALS9B

4.27e-06342228877989
Pubmed

Galectin-9 is required for endometrial regenerative cells to induce long-term cardiac allograft survival in mice.

LGALS9C LGALS9B

4.27e-06342233153471
Pubmed

Galectin-9 ameliorates immune complex-induced arthritis by regulating Fc gamma R expression on macrophages.

LGALS9C LGALS9B

4.27e-06342219800850
Pubmed

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

LGALS9C LGALS9B

4.27e-06342222052881
Pubmed

Galectin-9 protects mice from the Shwartzman reaction by attracting prostaglandin E2-producing polymorphonuclear leukocytes.

LGALS9C LGALS9B

4.27e-06342217560833
Pubmed

The effect of Toxoplasma gondii infection on galectin-9 expression in decidual macrophages contributing to dysfunction of decidual NK cells during pregnancy.

LGALS9C LGALS9B

4.27e-06342238987795
Pubmed

Myosin III-mediated cross-linking and stimulation of actin bundling activity of Espin.

MYO3A MYO3B

4.27e-06342226785147
Pubmed

Galectin-9 supports primary T cell transendothelial migration in a glycan and integrin dependent manner.

LGALS9C LGALS9B

4.27e-06342235643073
Pubmed

Galectin-9 functionally impairs natural killer cells in humans and mice.

LGALS9C LGALS9B

4.27e-06342223408620
Pubmed

Galectin-9/TIM-3 interaction regulates virus-specific primary and memory CD8 T cell response.

LGALS9C LGALS9B

8.53e-06442220463811
Pubmed

SARS-Cov-2 spike induces intestinal barrier dysfunction through the interaction between CEACAM5 and Galectin-9.

LGALS9C LGALS9B

8.53e-06442238686388
Pubmed

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells.

LGALS9C LGALS9B

8.53e-06442222677125
Pubmed

Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas.

LGALS9C LGALS9B

8.53e-06442232855403
Pubmed

Galectin-3 mediates oligomerization of secreted hensin using its carbohydrate-recognition domain.

LGALS9C LGALS9B

8.53e-06442223657851
Pubmed

Role of Tim-3/galectin-9 inhibitory interaction in viral-induced immunopathology: shifting the balance toward regulators.

LGALS9C LGALS9B

8.53e-06442219234217
Pubmed

[Expression and significance of galectin-3 and galectin-9 in mice nasal mucosa with allergic rhinitis].

LGALS9C LGALS9B

8.53e-06442218826117
Pubmed

Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.

MYO3A MYO3B

8.53e-06442226926603
Pubmed

The Tim-3/galectin-9 pathway involves in the homeostasis of hepatic Tregs in a mouse model of concanavalin A-induced hepatitis.

LGALS9C LGALS9B

8.53e-06442224333756
Pubmed

The expression of Galectin-9 correlates with mTOR and AMPK in murine colony-forming erythroid progenitors.

LGALS9C LGALS9B

8.53e-06442238853593
Pubmed

Tim-3/Galectin-9 signaling pathway is involved in the cytokine changes in mice with alveolar echinococcosis.

LGALS9C LGALS9B

8.53e-06442235715604
Pubmed

Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies.

LGALS9C LGALS9B

8.53e-06442224958847
Pubmed

Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions.

LGALS9C LGALS9B

8.53e-06442219017954
Pubmed

Galectin-9 binds IgM-BCR to regulate B cell signaling.

LGALS9C LGALS9B

8.53e-06442230120235
Pubmed

Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.

LGALS9C LGALS9B

8.53e-06442233963043
Pubmed

A locus coeruleus to dentate gyrus noradrenergic circuit modulates aversive contextual processing.

SLC17A7 DBH

8.53e-06442234081911
Pubmed

Galectin-9: A novel promoter of atherosclerosis progression.

LGALS9C LGALS9B

8.53e-06442236459823
Pubmed

[Expression of Galectin-9 and Tim-3 in lungs of mice with asthma].

LGALS9C LGALS9B

8.53e-06442221575348
Pubmed

Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts.

LGALS9C LGALS9B

8.53e-06442218346632
Pubmed

Isolation and characterization of a novel eosinophil-specific galectin released into the lungs in response to allergen challenge.

LGALS9C LGALS9B

8.53e-06442211839756
Pubmed

Newly characterized decidual Tim-3+ Treg cells are abundant during early pregnancy and driven by IL-27 coordinately with Gal-9 from trophoblasts.

LGALS9C LGALS9B

8.53e-06442233107565
Pubmed

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.

LGALS9C LGALS9B

8.53e-06442219670381
Pubmed

Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models.

LGALS9C LGALS9B

8.53e-06442229611821
Pubmed

Lipopolysaccharide mediates time-dependent macrophage M1/M2 polarization through the Tim-3/Galectin-9 signalling pathway.

LGALS9C LGALS9B

8.53e-06442230763585
Pubmed

Recipient T cell TIM-3 and hepatocyte galectin-9 signalling protects mouse liver transplants against ischemia-reperfusion injury.

LGALS9C LGALS9B

8.53e-06442225450716
Pubmed

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity.

LGALS9C LGALS9B

8.53e-06442216286920
Pubmed

Galectin-9 regulates the threshold of B cell activation and autoimmunity.

LGALS9C LGALS9B

8.53e-06442234369876
Pubmed

Lgals9 deficiency ameliorates obesity by modulating redox state of PRDX2.

LGALS9C LGALS9B

8.53e-06442233727589
Pubmed

Tim-3-Galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells.

LGALS9C LGALS9B

8.53e-06442219362679
Pubmed

Targeting the CD146/Galectin-9 axis protects the integrity of the blood-brain barrier in experimental cerebral malaria.

LGALS9C LGALS9B

8.53e-06442233203936
Pubmed

The Galectin-9/Tim-3 pathway is involved in the regulation of NK cell function at the maternal-fetal interface in early pregnancy.

LGALS9C LGALS9B

8.53e-06442225578313
Pubmed

Intestinal Lamina Propria CD4+ T Cells Promote Bactericidal Activity of Macrophages via Galectin-9 and Tim-3 Interaction during Salmonella enterica Serovar Typhimurium Infection.

LGALS9C LGALS9B

8.53e-06442229844236
Pubmed

Influence of galectin-9/Tim-3 interaction on herpes simplex virus-1 latency.

LGALS9C LGALS9B

8.53e-06442222021615
Pubmed

Embryonic implantation in galectin 1/galectin 3 double mutant mice.

LGALS9C LGALS9B

1.42e-0554229566950
Pubmed

Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.

LGALS9C LGALS9B

1.42e-05542229242193
Pubmed

Tim-3 signaling in peripheral NK cells promotes maternal-fetal immune tolerance and alleviates pregnancy loss.

LGALS9C LGALS9B

1.42e-05542228951537
Pubmed

Feto-maternal immune regulation by TIM-3/galectin-9 pathway and PD-1 molecule in mice at day 14.5 of pregnancy.

LGALS9C LGALS9B

1.42e-05542226278059
Pubmed

MyD88 and TNF receptor-associated factor 6 are critical signal transducers in Helicobacter pylori-infected human epithelial cells.

NOD1 MAP3K7

1.42e-05542216517750
Pubmed

Galectin-9 mediates neutrophil capture and adhesion in a CD44 and β2 integrin-dependent manner.

LGALS9C LGALS9B

1.42e-05542234847625
Pubmed

A single-vector intersectional AAV strategy for interrogating cellular diversity and brain function.

SLC17A7 DBH

1.42e-05542238802592
Pubmed

Tim-2 up-regulation and galectin-9-Tim-3 pathway activation in Th2-biased response in Schistosoma japonicum infection in mice.

LGALS9C LGALS9B

1.42e-05542222469568
Pubmed

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

LGALS9C LGALS9B

1.42e-05542237352334
Pubmed

Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model.

LGALS9C LGALS9B

1.42e-05542233664349
Pubmed

The glucose transporter 2 regulates CD8+ T cell function via environment sensing.

LGALS9C LGALS9B

1.42e-05542237884694
Pubmed

Astrocyte galectin-9 potentiates microglial TNF secretion.

LGALS9C LGALS9B

1.42e-05542225158758
Pubmed

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.

LGALS9C LGALS9B

1.42e-05542221385853
Pubmed

C/EBPzeta (CHOP/Gadd153) is a negative regulator of LPS-induced IL-6 expression in B cells.

LGALS9C LGALS9B

1.42e-05542219782405
Pubmed

Tim3 binding to galectin-9 stimulates antimicrobial immunity.

LGALS9C LGALS9B

2.13e-05642220937702
Pubmed

Galectins in mouse embryogenesis.

LGALS9C LGALS9B

2.13e-0564228674632
Pubmed

Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.

LGALS9C LGALS9B

2.13e-05642228394331
Cytoband15q24.1

CYP1A1 CCDC33

4.50e-043442215q24.1
GeneFamilyMyosins, class III|Deafness associated genes

MYO3A MYO3B

3.03e-0623221099
GeneFamilyGalectins

LGALS9C LGALS9B

3.14e-0415322629
GeneFamilySolute carriers

SLC17A7 SLC37A2 SLC13A4 SLC7A14

4.97e-03395324752
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP

LGALS9C TMEM176B DYSF PLXDC2 LGALS9B

1.09e-05188415MM983
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC37A2 SLFN11 TMEM176B DYSF PLXDC2

1.03e-0619342593ba635ed69fec9286fe7636b9d258f3d93a22c3
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC37A2 SLFN11 TMEM176B DYSF PLXDC2

1.03e-061934256dfdeb793cb5ad6412b6f808b5687a4e74b6ec65
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC37A2 SLFN11 TMEM176B DYSF PLXDC2

1.06e-06194425e0cfd18a7ea2251163d61312b9397f8a518c8c51
ToppCellBAL-Mild-Myeloid-MoAM-MoAM3-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC37A2 SLFN11 TMEM176B DYSF PLXDC2

1.06e-06194425e455cb469157c044126f9b0b308957d4ee1e608b
ToppCellMild_COVID-19-Myeloid-MoAM3|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

SLC37A2 SLFN11 TMEM176B DYSF PLXDC2

1.11e-061964259faad17aa0b6af5a8ec2dadf7d70b9209d658072
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC37A2 LRRK1 PLXDC2 IGSF21 FCHO1

1.14e-06197425dea1d29154c585ab588e50b83c7c8de7fe24d2d4
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC17A7 PARP4 LRRK1 HTR1F PLXDC2

1.23e-062004251a3d29a580d1b405a74869a1da3e818c581fc559
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E---L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC17A7 PARP4 LRRK1 HTR1F PLXDC2

1.23e-062004256f9ed8fe9cda91185c3a1a675353e11b8fec6ef1
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E--|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC17A7 PARP4 LRRK1 HTR1F PLXDC2

1.23e-0620042586705dfc05b3e1576543b93883c88fb55b742855
ToppCellNeuronal-Excitatory-eB(RORB)-SEMA3E|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC17A7 PARP4 LRRK1 HTR1F PLXDC2

1.23e-06200425db194b4f524fd008b3c5b4b6014b436190a1b87a
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HTR1F IGSF21 STK26 CCDC33

5.32e-0612242437612ad087d9c11d4a3466244ab36224de31930b
ToppCellfacs-Heart-LV-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMAHP IGSF21 FCHO1 MYO3B

1.84e-051674244a669eafde3582a451614ad304769b47aa1d9578
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMAHP IGSF21 FCHO1 MYO3B

1.92e-05169424ae85cef7ef8f761c19f4af2a23fe333641c38a92
ToppCellfacs-Heart-LV-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMAHP IGSF21 FCHO1 MYO3B

1.92e-05169424c01bc3f2f299109086ded83dc11e98559bf1940c
ToppCellfacs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 AGK CYP1A1 PTDSS1

1.97e-0517042412203d4410f38cc933d9f160b5fb76828df94119
ToppCellfacs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 AGK CYP1A1 PTDSS1

1.97e-05170424f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176B USH2A DNAH9 MYO3B

2.11e-0517342466f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM176B USH2A DNAH9 MYO3B

2.11e-05173424649b08a409095592cccf31883be69c754411280d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 LRRK1 HTR1F CMAHP

2.16e-05174424b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 LRRK1 HTR1F CMAHP

2.36e-05178424731e1e8eff2c4018c75dfc66632a316010a09a9a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.41e-05179424445eeb0356d9fd894aa33dd9f45d893b21424149
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 SLC7A14

2.41e-05179424747a32460b257fffca30527b56a74720eb9c12e4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.41e-051794241ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.41e-05179424065a50952e8703fa07767beb6b73a090bf378ca6
ToppCellwk_15-18-Hematologic-Myeloid-APOE+_Mac2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SLFN11 LRRK1 TMEM176B IGSF21

2.46e-05180424c630a121aedd09a51ea18cc6e8552eb979e5b555
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.52e-051814249de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.57e-05182424cc6f9d606a4f8717dc44928ceec2a257636043fd
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.57e-0518242431efc06d6b073e8e341648207093e5f33c6f9183
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.57e-0518242435b2a5625323bf0917214d3b82fafc4a8f5e75ff
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F PLXDC2 IGSF21

2.68e-051844249a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCell(6)_Endothelial-F_(Lymphatics)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

KLHL3 PGAP4 SEMA6A DYSF

2.68e-0518442403ea613e00b45c81b752c14505a0538d698f551e
ToppCellBAL-Severe-Myeloid-Macrophage|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC37A2 TMEM176B PLXDC2 IGSF21

2.74e-051854249aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC37A2 TMEM176B PLXDC2 IGSF21

2.74e-051854243beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCellBAL-Severe-Myeloid-Macrophage-transitional_Macro|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC37A2 TMEM176B PLXDC2 IGSF21

2.74e-0518542442939b294ea3e871274d8b73124c850dc1904fd2
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KLHL3 PGAP4 SEMA6A DYSF

2.74e-05185424f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCellSevere_COVID-19-Myeloid-transitional_Macro|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

SLC37A2 TMEM176B PLXDC2 IGSF21

2.74e-05185424f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO3A DBH MYO3B

3.03e-0564423bf923a66b17e717b8d3817b9d0e201b82a7e4a88
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO3A DBH MYO3B

3.03e-0564423f8f43ad9354c786b418bac54614f96f50e8bea68
ToppCellHippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MYO3A DBH MYO3B

3.03e-0564423a3e852600c53b11175eb579e92962fa711f5678b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC37A2 LRRK1 PLXDC2 FCHO1

3.23e-051934243e3d7cb3e7242ec9c9677e07e303835649852b52
ToppCellwk_20-22-Endothelial-Lymph_endothelial-Lymphatic_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KLHL3 PGAP4 SEMA6A DYSF

3.30e-05194424640ff8da7084a9486fc2752493b8d8059ecf4ab7
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC37A2 TMEM176B PLXDC2 IGSF21

3.50e-05197424e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCellcellseq-Immune-Immune_Myeloid-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC37A2 TMEM176B PLXDC2 IGSF21

3.64e-05199424b3267d5a7ae0461f5e9e6a3ab6783317a8c42506
ToppCellcellseq-Immune-Immune_Myeloid-IM-IM|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SLC37A2 TMEM176B PLXDC2 IGSF21

3.64e-0519942401dacee8bb392639d475be3cb27ba3eeff1e57f1
ToppCellNeuronal-Excitatory-eC(RORB)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SLC17A7 LRRK1 HTR1F CMAHP

3.72e-052004248c803a0ce25e140b46036f6aabefc5502601f408
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC37A2 TMEM176B PLXDC2 IGSF21

3.72e-0520042478d75d381cb2b9a4c9eb7c32a07b014eaee39195
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_B|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CYP1A1 SEMA6A DYSF

2.12e-04123423e0130010aa406d4e9d8f16ad32858c382277eeb2
ToppCelldroplet-Heart-nan-18m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A1 DYSF IGSF21

2.27e-04126423de09142c12fd2ad6ecc3e7707015582f751eb426
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRK1 SLC13A4 CMAHP

2.78e-041354234cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRK1 SLC13A4 CMAHP

2.78e-041354236bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRK1 SLC13A4 CMAHP

2.78e-041354237e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)|Hippocampus / BrainAtlas - Mouse McCarroll V32

LRRK1 SLC13A4 CMAHP

2.78e-0413542397989546826bf3739e1b86a10832a457fd37c5d2
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC17A7 MYO3B CCDC33

3.36e-04144423e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA6A SLC7A14 MYO3B

3.64e-041484235e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A7 HTR1F IGSF21

3.86e-04151423f50c5ae9dae507df750df25e151b58685fec70ce
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYO3A SEMA6A MYO3B

3.94e-04152423fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellFrontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HTR1F IGSF21 STK26

4.02e-04153423b37a1ecad389d2848b8ca4d287823e8048207420
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DNAH9 PTPN20 CCDC33

4.02e-04153423fc0d2d50aa3b6b2772bbf3626c9df5c5e8d7d11e
ToppCellPND01-03-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DNAH9 PTPN20 CCDC33

4.02e-041534232482247d9c39c7b99bb45fb9153442f64fd6012f
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KLHL3 PGAP4 MYO3B

4.09e-04154423ea5d0da5dd8ccfc19969aec35f044db77d589f54
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

USH2A DNAH9 CCDC33

4.09e-0415442358072ce422d09f2de602580325eaac6c4ec6c136
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_ALM_Cpa6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A7 HTR1F IGSF21

4.09e-0415442312cbc38bc1f7231c67e1d2d5e86e95bc12e24682
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

USH2A DNAH9 CCDC33

4.09e-041544239ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_CT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A7 HTR1F IGSF21

4.25e-04156423fe383ce3a0c37f7343d7026cb51260a04d4c2829
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1A1 SEMA6A DYSF

4.25e-04156423ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1A1 SEMA6A DYSF

4.25e-04156423586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZSWIM4 LGALS9B BIVM

4.41e-041584234d997efc36fd8946775fe74dd9ac9ccd5ade64ff
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KLHL3 DYSF FCHO1

4.58e-0416042333050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LGALS9C AGK LGALS9B

4.75e-041624239b1c07f0af657095379380c39d763cab0ad73e74
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A7 HTR1F IGSF21

4.75e-0416242358da6bc04cdac0002b0e6a751c96ff95e1a7f70f
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC17A7 HTR1F IGSF21

4.75e-041624234d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCellInfluenza_Severe-NK_CD56bright|Influenza_Severe / Disease group and Cell class

AGK SLC13A4 LGALS9B

4.83e-041634237748d5709e8cf6673f5a8370108309f76cd830f4
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SLC13A4 TMEM176B IGSF21

4.83e-041634234b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA6A CMAHP DYSF

4.92e-041644231592a5becad7e0f3f990f0d7581d75fcfc7da023
ToppCellCiliated_cells-B-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LGALS9B DNAH9 CCDC33

4.92e-041644230e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCellfacs-Brain_Myeloid-Hippocampus-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CMAHP IGSF21 USH2A

5.01e-04165423ab6ed7e30096c418e7be2d5eec33feeddd1387d9
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

TMEM176B PLXDC2 IGSF21

5.09e-04166423fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D122|Adult / Lineage, Cell type, age group and donor

SLC37A2 PLXDC2 IGSF21

5.09e-04166423be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC37A2 PLXDC2 IGSF21

5.27e-0416842326fce414439ccd204e3acb41f2b4f75072df5a26
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC37A2 PLXDC2 IGSF21

5.27e-0416842361a5435b27b01ff1a509ea463a6af220c5d2c9b3
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRRK1 PLXDC2 PTPN20

5.27e-04168423d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYO3A FCHO1 MYO3B

5.27e-041684232d2eab3190374f79f373e31c8b062ff4e1766396
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F CMAHP

5.27e-041684231d58731a481ecac84c15affa84f8041dd67d944c
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYO3A FCHO1 MYO3B

5.27e-04168423df58156721457b34af1e81c0eb8a7243cbbfb303
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SEMA6A DYSF LGALS9B

5.37e-04169423987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Myeloid-cDC1|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPM1M LRRK1 DYSF

5.37e-04169423da3485d77bb7876fad4f166f6099e681b27457ae
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK1 HTR1F CMAHP

5.37e-04169423319cba07263bf41fcbcbfecd117f91b729394241
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

CYP1A1 PLXDC2 IGSF21

5.37e-041694232c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LRRK1 PLXDC2 PTPN20

5.37e-04169423ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USH2A DNAH9 MYO3B

5.37e-0416942312bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F CMAHP

5.46e-0417042349fc45d8a5c3ad89d1649fa46d7a285891379392
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 CYP1A1 ZSWIM4

5.46e-0417042367d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK1 HTR1F CMAHP

5.46e-041704233174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 CYP1A1 ZSWIM4

5.46e-041704238e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

VIL1 SLC37A2 PLXDC2

5.46e-041704233a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 LRRK1 HTR1F

5.55e-04171423f648789e6aefe508bb748401bf9b3cd830fb0ddf
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_CMAHP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SLC17A7 HTR1F CMAHP

5.55e-041714239d5cabd71a901a00eb16c4d151189296f1b3bf6f
ToppCellfacs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGK CMAHP STK26

5.55e-04171423f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VIL1 SLC37A2 TMEM176B

5.55e-04171423b520d4d5620cac08315e4cbb7e796c5e9e233060
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CMAHP FCHO1 STK26

5.65e-0417242376c06a968d3333441eed103abef1e636a1c3e7a1
Diseaseage of onset of anorexia nervosa

CMAHP PTPN20

3.38e-057382OBA_2050099
Diseasesensorineural hearing loss (implicated_via_orthology)

DNAH9 SLC7A14

2.72e-0419382DOID:10003 (implicated_via_orthology)
Diseasetobacco smoke exposure measurement

CYB561D1 DBH

4.38e-0424382EFO_0009115
Diseasedilated cardiomyopathy (is_marker_for)

CYP1A1 MAP3K7

1.16e-0339382DOID:12930 (is_marker_for)
Diseasecups of coffee per day measurement

CYP1A1 CCDC33

1.22e-0340382EFO_0006782
Diseasecortical surface area measurement

SEMA6A ZSWIM4 DYSF PLXDC2 MAP3K7 PTPN20 CCDC33

1.47e-031345387EFO_0010736

Protein segments in the cluster

PeptideGeneStartEntry
QPVFAMTGLRWGSFR

AGK

201

Q53H12
RPGTSLFSWHPVFMA

CYB561D1

46

Q8N8Q1
MAFRGPEPWVSASLL

CCDC33

1

Q8N5R6
SVFISMPPLFWRHQG

HTR1F

151

P30939
IRFGPFTGNTTLMRW

BIVM

256

Q86UB2
PFTVFRWCPGVRMRF

RBM22

51

Q9NW64
MSFSPDSGPVWAARR

CYP1A1

121

P04798
GTPMGTFAPLWEVFR

FCHO1

61

O14526
SFVPVGFWQRFIARM

LRRK1

1021

Q38SD2
WFPGARCAIRMTQSP

IGKV1D-43

16

A0A0B4J1Z2
PRKMPFVRGQSFSVW

LGALS9C

296

Q6DKI2
PRKMPFVRGQSFSVW

LGALS9B

296

Q3B8N2
SSPARMSSAVWVFPR

PNMA6E

581

A0A0J9YXQ4
AFRIMWAVHNGTRPP

MAP3K7

236

O43318
LRFFQEWMPPAGAAT

NOD1

541

Q9Y239
MRFASRPGFSWPVML

PGAP4

281

Q9BRR3
GTVGVFFMPATVAPW

PARP4

741

Q9UKK3
SGSDPSMWTARGPFR

PTPN20

76

Q4JDL3
MRSSLAPGVWFFRAF

SLC37A2

1

Q8TED4
FPEPMFTWTRVGSRL

IGSF21

371

Q96ID5
RWASLPGPSMREAAF

DBH

6

P09172
WFFVAPMNTRRSSVG

KLHL3

421

Q9UH77
MVPESWARRAYPSTA

DNAH9

4301

Q9NYC9
MTVLWFTREPGFVPG

SLC13A4

386

Q9UKG4
RMPRLAWFPLTRGSQ

DYSF

1251

O75923
ASRTASFRWSPPMFP

USH2A

4841

O75445
RNTFVGTPFWMAPEV

STK26

176

Q9P289
SIFFIERRPSRWPAM

PLXDC2

486

Q6UX71
MQPFFRGILIFSRSW

SLFN11

431

Q7Z7L1
FSTPWRRFFTSMPVY

SLC17A7

291

Q9P2U7
RSDPVFPTTGYRWMR

TMEM176B

166

Q3YBM2
RMVFDPWLIGPAFAR

CMAHP

51

Q9Y471
MAWRVPGVRPASTFF

LINC01561

1

Q8N1V8
MSGFFTSLDPRRVQW

SLC7A14

1

Q8TBB6
AFGMTPAAFSALPRW

VIL1

801

P09327
AVPSIFNRPWFLRTM

SEMA6A

401

Q9H2E6
MSAGWFRRRFLPGEP

PPM1M

1

Q96MI6
FMPAWEVVTSAIPRG

ZNF419

86

Q96HQ0
GPFTRPHPALWRMVF

PTDSS1

91

P48651
SPLDSIMSNRFPRWF

ZSWIM4

586

Q9H7M6
RRNTSVGTPFWMAPE

MYO3A

181

Q8NEV4
LRRNTSVGTPFWMAP

MYO3B

186

Q8WXR4