Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	heart valve development	TIE1 MATR3 FGFRL1 ZFPM1 SCX	2.45e-05	78	91	5	GO:0003170
GeneOntologyCellularComponent	chromatin	FOXN1 SPHK2 FOXD4L4 UNCX CPSF6 BICRA HES7 TLX3 SOX17 NR5A1 CAMTA2 FOXD4L6 ZFPM1 TAF4 DBP KMT2E EN1 SCX KDM4B FOXD4L5	4.47e-06	1480	91	20	GO:0000785
GeneOntologyCellularComponent	postsynaptic specialization	SHANK1 PRR12 ABI1 PSD DROSHA IQSEC2 NLGN2 SCRIB CTNND2 PRR7	6.69e-05	503	91	10	GO:0099572
GeneOntologyCellularComponent	neuron to neuron synapse	SHANK1 PRR12 ABI1 PSD DROSHA IQSEC2 NLGN2 SCRIB CTNND2 PRR7	9.23e-05	523	91	10	GO:0098984
GeneOntologyCellularComponent	postsynaptic density	SHANK1 PRR12 ABI1 PSD DROSHA IQSEC2 SCRIB CTNND2 PRR7	1.53e-04	451	91	9	GO:0014069
GeneOntologyCellularComponent	mRNA cleavage and polyadenylation specificity factor complex	CPSF6 FIP1L1 CPSF7	1.93e-04	26	91	3	GO:0005847
GeneOntologyCellularComponent	asymmetric synapse	SHANK1 PRR12 ABI1 PSD DROSHA IQSEC2 SCRIB CTNND2 PRR7	2.33e-04	477	91	9	GO:0032279
GeneOntologyCellularComponent	nuclear protein-containing complex	CASC3 INTS5 KMT2D AAAS CPSF6 DROSHA BICRA FIP1L1 NR5A1 MSH3 TAF4 DBP KMT2E SF3A2 SLX1A CPSF7	2.73e-04	1377	91	16	GO:0140513
GeneOntologyCellularComponent	mRNA cleavage factor complex	CPSF6 FIP1L1 CPSF7	3.28e-04	31	91	3	GO:0005849
GeneOntologyCellularComponent	transcription regulator complex	SKOR2 SOX17 NR5A1 ZFPM1 TAF4 DBP SNAPC4 SPEN SCX	1.15e-03	596	91	9	GO:0005667
GeneOntologyCellularComponent	SCAR complex	ABI1 WASF2	1.20e-03	12	91	2	GO:0031209
GeneOntologyCellularComponent	postsynaptic density, intracellular component	PSD IQSEC2 PRR7	1.27e-03	49	91	3	GO:0099092
GeneOntologyCellularComponent	postsynapse	SHANK1 PRR12 ABI1 PSD DROSHA CASKIN1 IQSEC2 NLGN2 SCRIB CTNND2 PRR7 AGAP2	1.51e-03	1018	91	12	GO:0098794
GeneOntologyCellularComponent	postsynaptic specialization, intracellular component	PSD IQSEC2 PRR7	1.87e-03	56	91	3	GO:0099091
Domain	AUTS2	FBRS FBRSL1	7.02e-05	3	91	2	IPR023246
Domain	TF_fork_head_CS_2	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	7.36e-05	46	91	4	IPR030456
Domain	TF_fork_head_CS_1	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	8.01e-05	47	91	4	IPR018122
Domain	FH	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	9.45e-05	49	91	4	SM00339
Domain	FORK_HEAD_1	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	9.45e-05	49	91	4	PS00657
Domain	FORK_HEAD_2	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	9.45e-05	49	91	4	PS00658
Domain	Fork_head_dom	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	9.45e-05	49	91	4	IPR001766
Domain	FORK_HEAD_3	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	9.45e-05	49	91	4	PS50039
Domain	Forkhead	FOXN1 FOXD4L4 FOXD4L6 FOXD4L5	9.45e-05	49	91	4	PF00250
Domain	DUF1908	MAST2 MAST3	1.40e-04	4	91	2	PF08926
Domain	MA_Ser/Thr_Kinase_dom	MAST2 MAST3	1.40e-04	4	91	2	IPR015022
Domain	MAST_pre-PK_dom	MAST2 MAST3	1.40e-04	4	91	2	IPR023142
Domain	-	MAST2 MAST3	1.40e-04	4	91	2	1.20.1480.20
Domain	GBD/FH3_dom	INF2 FHOD1	1.25e-03	11	91	2	IPR014768
Domain	GBD_FH3	INF2 FHOD1	1.25e-03	11	91	2	PS51232
Domain	Znf_C2H2_matrin	MATR3 SF3A2	1.50e-03	12	91	2	IPR000690
Domain	WH2	INF2 WASF2	2.06e-03	14	91	2	SM00246
Domain	-	PSD IQSEC2	2.37e-03	15	91	2	1.10.1000.11
Domain	Sec7	PSD IQSEC2	2.37e-03	15	91	2	PF01369
Domain	FH2	INF2 FHOD1	2.37e-03	15	91	2	PS51444
Domain	Sec7_alpha_orthog	PSD IQSEC2	2.37e-03	15	91	2	IPR023394
Domain	FH2_Formin	INF2 FHOD1	2.37e-03	15	91	2	IPR015425
Domain	FH2	INF2 FHOD1	2.37e-03	15	91	2	PF02181
Domain	FH2	INF2 FHOD1	2.37e-03	15	91	2	SM00498
Domain	Sec7	PSD IQSEC2	2.70e-03	16	91	2	SM00222
Domain	SEC7	PSD IQSEC2	2.70e-03	16	91	2	PS50190
Domain	Sec7_dom	PSD IQSEC2	2.70e-03	16	91	2	IPR000904
Domain	WH2	INF2 WASF2	2.70e-03	16	91	2	PF02205
Domain	ZF_MATRIN	MATR3 SF3A2	3.41e-03	18	91	2	PS50171
Domain	SH3	SHANK1 PRAM1 SH3PXD2B ABI1 CASKIN1	4.11e-03	216	91	5	SM00326
Domain	SH3	SHANK1 PRAM1 SH3PXD2B ABI1 CASKIN1	4.11e-03	216	91	5	PS50002
Domain	SH3_domain	SHANK1 PRAM1 SH3PXD2B ABI1 CASKIN1	4.44e-03	220	91	5	IPR001452
Domain	WH2_dom	INF2 WASF2	4.64e-03	21	91	2	IPR003124
Domain	PDZ	SHANK1 SCRIB MAST2 MAST3	5.01e-03	141	91	4	PF00595
Domain	EPHD	KMT2D KDM4B	5.09e-03	22	91	2	PS51805
Domain	Ank	SHANK1 CASKIN1 CAMTA2 NOTCH3 AGAP2	5.16e-03	228	91	5	PF00023
Domain	TUDOR	KDM4B ALG13	5.56e-03	23	91	2	PS50304
Domain	PHD	KMT2D KMT2E KDM4B	5.87e-03	75	91	3	PF00628
Domain	PDZ	SHANK1 SCRIB MAST2 MAST3	5.94e-03	148	91	4	SM00228
Domain	WH2	INF2 WASF2	6.04e-03	24	91	2	PS51082
Domain	-	SHANK1 SCRIB MAST2 MAST3	6.22e-03	150	91	4	2.30.42.10
Domain	PDZ	SHANK1 SCRIB MAST2 MAST3	6.37e-03	151	91	4	PS50106
Domain	PDZ	SHANK1 SCRIB MAST2 MAST3	6.52e-03	152	91	4	IPR001478
Domain	-	SHANK1 CASKIN1 CAMTA2 NOTCH3 AGAP2	7.30e-03	248	91	5	1.25.40.20
Domain	ANK_REPEAT	SHANK1 CASKIN1 CAMTA2 NOTCH3 AGAP2	7.93e-03	253	91	5	PS50088
Domain	Ankyrin_rpt-contain_dom	SHANK1 CASKIN1 CAMTA2 NOTCH3 AGAP2	8.06e-03	254	91	5	IPR020683
Domain	ANK_REP_REGION	SHANK1 CASKIN1 CAMTA2 NOTCH3 AGAP2	8.06e-03	254	91	5	PS50297
Domain	SH3_2	SHANK1 SH3PXD2B CASKIN1	8.56e-03	86	91	3	IPR011511
Domain	SH3_2	SHANK1 SH3PXD2B CASKIN1	8.56e-03	86	91	3	PF07653
Domain	ZnF_U1	MATR3 SF3A2	8.75e-03	29	91	2	SM00451
Domain	Znf_U1	MATR3 SF3A2	8.75e-03	29	91	2	IPR003604
Domain	Ankyrin_rpt	SHANK1 CASKIN1 CAMTA2 NOTCH3 AGAP2	9.14e-03	262	91	5	IPR002110
Domain	Tudor	KDM4B ALG13	9.35e-03	30	91	2	IPR002999
Domain	PHD	KMT2D KMT2E KDM4B	9.40e-03	89	91	3	SM00249
Pathway	REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS	CPSF6 FIP1L1 CPSF7	7.55e-05	20	59	3	M497
Pathway	REACTOME_PROCESSING_OF_INTRONLESS_PRE_MRNAS	CPSF6 FIP1L1 CPSF7	7.55e-05	20	59	3	MM15469
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION	CASC3 CPSF6 FIP1L1 CPSF7	1.29e-04	62	59	4	MM15426
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	CASC3 AAAS PRCC CPSF6 FIP1L1 SF3A2 CPSF7	1.49e-04	277	59	7	MM15414
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	CASC3 AAAS PRCC CPSF6 FIP1L1 SF3A2 CPSF7	1.70e-04	283	59	7	M13087
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION_TERMINATION	CASC3 CPSF6 FIP1L1 CPSF7	1.74e-04	67	59	4	M27694
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA	CPSF6 FIP1L1 CPSF7	2.36e-04	29	59	3	M783
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA	CPSF6 FIP1L1 CPSF7	2.36e-04	29	59	3	MM15444
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CNPPD1 PITPNM2 PHLDB3 PRR12 NHSL1 SPHK2 SH3PXD2B INTS5 KMT2D INF2 BICRA CASKIN1 FBRS FBRSL1 FGFRL1 NLGN2 ZFPM1 SNAPC4 MAST2 SPEN	1.35e-11	1105	94	20	35748872
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 CASC3 SH3PXD2B MAP7D1 ABI1 WASF2 CASKIN1 MATR3 IQSEC2 RANBP9 NLGN2 SCRIB TAF4 CTNND2 LMTK3 PRRC2A AGAP2	8.20e-10	963	94	17	28671696
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXN1 FOXD4L4 KMT2D UNCX SKOR2 HES7 TLX3 SOX17 PLAGL1 NR5A1 CAMTA2 ZFPM1 DBP SNAPC4 EN1	2.17e-08	908	94	15	19274049
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	INTS5 KMT2D FHOD1 MATR3 FIP1L1 IRF2BPL ZFPM1 SCRIB SNAPC4 SPEN MN1 PRRC2A KDM4B WDR62	2.19e-08	774	94	14	15302935
Pubmed	A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.	FOXD4L4 FOXD4L6 EN1 FOXD4L5	3.51e-08	13	94	4	16884697
Pubmed	Inducing mutations in the mouse genome with the chemical mutagen ethylnitrosourea.	FOXN1 KMT2D PCDH15	7.63e-08	4	94	3	16972005
Pubmed	Molecular Mechanisms for CFIm-Mediated Regulation of mRNA Alternative Polyadenylation.	CPSF6 FIP1L1 CPSF7	7.63e-08	4	94	3	29276085
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	CPSF6 DROSHA MATR3 FBRS FIP1L1 PRRC2A SF3A2 CPSF7	1.57e-07	220	94	8	24550385
Pubmed	Functional equivalency between Otx2 and Otx1 in development of the rostral head.	FOXD4L4 FOXD4L6 EN1 FOXD4L5	1.88e-07	19	94	4	9895322
Pubmed	FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.	FOXD4L4 FOXD4L6 FOXD4L5	1.90e-07	5	94	3	12234674
Pubmed	Human transcription factor protein interaction networks.	PRR12 MAP7D1 KMT2D PRCC BICRA MATR3 TLX3 FBRS SOX17 FBRSL1 FIP1L1 IRF2BPL TAF4 EN1 SPEN PRRC2A CPSF7	2.60e-07	1429	94	17	35140242
Pubmed	Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.	FOXD4L4 FOXD4L6 EN1 FOXD4L5	2.89e-07	21	94	4	9449667
Pubmed	Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.	FOXD4L4 FOXD4L6 FOXD4L5	3.80e-07	6	94	3	27092474
Pubmed	A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.	FOXD4L4 FOXD4L6 EN1 FOXD4L5	5.10e-07	24	94	4	29992973
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	MAP7D1 VSTM2L MATR3 FIP1L1 CTNND2 MAST2 SPEN PRRC2A CPSF7	6.20e-07	361	94	9	26167880
Pubmed	Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.	FOXD4L4 UNCX FOXD4L6 FOXD4L5	7.15e-07	26	94	4	15857913
Pubmed	The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.	FOXD4L4 FOXD4L6 FOXD4L5	1.06e-06	8	94	3	8530406
Pubmed	The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity.	SHANK1 ABI1 WASF2 CTNND2	1.13e-06	29	94	4	19208628
Pubmed	An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.	FOXD4L4 FOXD4L6 FOXD4L5	1.59e-06	9	94	3	12412011
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	CASKIN1 MATR3 CTNND2 LMTK3 PRRC2A MAST3 AGAP2	3.26e-06	231	94	7	16452087
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	NHSL1 CASC3 SH3PXD2B MAP7D1 ABI1 MATR3 IQSEC2 DYRK1B FIP1L1 SCRIB MAST2 WDR62	3.65e-06	861	94	12	36931259
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	ABI1 CPSF6 WASF2 FIP1L1 SF3A2 CPSF7	4.04e-06	154	94	6	16055720
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ABI1 CASKIN1 DYRK1B NLGN2 CTNND2 LMTK3 PRRC2A AGAP2	4.78e-06	347	94	8	17114649
Pubmed	Interaction network of human early embryonic transcription factors.	PRR12 KMT2D BICRA FBRS FBRSL1 MSH3 TAF4 SPEN	5.20e-06	351	94	8	38297188
Pubmed	Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.	FOXD4L4 FOXD4L6 FOXD4L5	5.36e-06	13	94	3	7957066
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SHANK1 ABI1 CASKIN1 IQSEC2 NLGN2 CTNND2 AGAP2	5.63e-06	251	94	7	27507650
Pubmed	Rac1 signaling is critical to cardiomyocyte polarity and embryonic heart development.	ABI1 WASF2 SCRIB	6.81e-06	14	94	3	25315346
Pubmed	Abl interactor 1 binds to sos and inhibits epidermal growth factor- and v-Abl-induced activation of extracellular signal-regulated kinases.	ABI1 SOS2	7.23e-06	2	94	2	11003655
Pubmed	A WAVE2-Abi1 complex mediates CSF-1-induced F-actin-rich membrane protrusions and migration in macrophages.	ABI1 WASF2	7.23e-06	2	94	2	16280551
Pubmed	Multiple formin proteins participate in glioblastoma migration.	INF2 FHOD1	7.23e-06	2	94	2	32727404
Pubmed	Regulation of Arf activation: the Sec7 family of guanine nucleotide exchange factors.	PSD IQSEC2	7.23e-06	2	94	2	17850229
Pubmed	The formins FHOD1 and INF2 regulate inter- and intra-structural contractility of podosomes.	INF2 FHOD1	7.23e-06	2	94	2	26621033
Pubmed	The Wave complex controls epidermal morphogenesis and proliferation by suppressing Wnt-Sox9 signaling.	ABI1 WASF2	7.23e-06	2	94	2	30867227
Pubmed	Altered expression of MLL methyltransferase family genes in breast cancer.	KMT2D KMT2E	7.23e-06	2	94	2	23754336
Pubmed	Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.	UNCX HES7 NOTCH3	8.50e-06	15	94	3	14672936
Pubmed	PDZ-Containing Proteins Targeted by the ACE2 Receptor.	SHANK1 SCRIB MAST2	8.50e-06	15	94	3	34835087
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXD4L4 FOXD4L6 FOXD4L5	8.50e-06	15	94	3	7689224
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	FOXD4L4 FOXD4L6 FOXD4L5	8.50e-06	15	94	3	22045912
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	PRR12 PRAM1 MAP7D1 KMT2D UNCX CPSF6 BICRA FIP1L1 TAF4 SPEN PRRC2A SF3A2 CPSF7	8.55e-06	1103	94	13	34189442
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	MAP7D1 PSD DROSHA BICRA FBRS RANBP9 FBRSL1 FIP1L1 SCRIB TAF4 MAST2 WDR62 ALG13	9.69e-06	1116	94	13	31753913
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	PRR12 INTS5 MAP7D1 KMT2D AAAS MATR3 HES7 TLX3 FIP1L1 MSH3 TAF4 SPEN SF3A2 CPSF7	9.84e-06	1294	94	14	30804502
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	PRR12 CPSF6 MATR3 FIP1L1 NOTCH3 CPSF7	9.87e-06	180	94	6	35198878
Pubmed	Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.	FOXD4L4 FOXD4L6 FOXD4L5	1.04e-05	16	94	3	8861101
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXD4L4 FOXD4L6 FOXD4L5	1.04e-05	16	94	3	10208738
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	CASC3 CPSF6 DROSHA MATR3 FBRSL1 FIP1L1 SPEN PRRC2A SF3A2 CPSF7 ALG13	1.18e-05	807	94	11	22681889
Pubmed	Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.	CASC3 CPSF6 MATR3 FIP1L1	1.23e-05	52	94	4	26265008
Pubmed	The DNA sequence and biology of human chromosome 19.	PHLDB3 DYRK1B SF3A2 NOTCH3 KDM4B WDR62 MAST3	1.26e-05	284	94	7	15057824
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	CPSF6 BICRA MATR3 RANBP9 SCRIB PRRC2A SF3A2 CPSF7	1.32e-05	399	94	8	35987950
Pubmed	Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.	CASC3 MATR3 FIP1L1 SPEN SF3A2	1.51e-05	114	94	5	31553912
Pubmed	Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.	FOXD4L4 FOXD4L6 FOXD4L5	2.11e-05	20	94	3	12812790
Pubmed	Cleavage factor Im is a key regulator of 3' UTR length.	CPSF6 CPSF7	2.16e-05	3	94	2	23187700
Pubmed	Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition.	CPSF6 FIP1L1	2.16e-05	3	94	2	15937220
Pubmed	Modifying transcript lengths of cycling mouse segmentation genes.	UNCX HES7	2.16e-05	3	94	2	22326607
Pubmed	c-Abl interacts with the WAVE2 signaling complex to induce membrane ruffling and cell spreading.	ABI1 WASF2	2.16e-05	3	94	2	16899465
Pubmed	Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation.	ABI1 WASF2	2.16e-05	3	94	2	15657136
Pubmed	Evidence that cleavage factor Im is a heterotetrameric protein complex controlling alternative polyadenylation.	CPSF6 CPSF7	2.16e-05	3	94	2	20695905
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	SPATA31E1 BICRA IRF2BPL LMTK3 KMT2E SPEN PRR7 SOS2	2.25e-05	430	94	8	35044719
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2D KMT2E KDM4B	2.45e-05	21	94	3	27626377
Pubmed	Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.	FOXD4L4 FOXD4L6 FOXD4L5	2.84e-05	22	94	3	17389379
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SHANK1 PITPNM2 NHSL1 MAP7D1 ABI1 INF2 CASKIN1 MATR3 IQSEC2 SCRIB CTNND2 PRRC2A AGAP2 CPSF7	3.00e-05	1431	94	14	37142655
Pubmed	Gata2, Nkx2-2 and Skor2 form a transcription factor network regulating development of a midbrain GABAergic neuron subtype with characteristics of REM-sleep regulatory neurons.	SKOR2 ZFPM1 EN1	3.26e-05	23	94	3	35815619
Pubmed	Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.	FOXD4L4 FOXD4L6 FOXD4L5	3.71e-05	24	94	3	11820816
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 CNPPD1 DROSHA IQSEC2 RANBP9 FIP1L1 MSH3 SCRIB CTNND2 PRRC2A SF3A2 AGAP2 SOS2	4.22e-05	1285	94	13	35914814
Pubmed	Sox17-mediated expression of adherent molecules is required for the maintenance of undifferentiated hematopoietic cluster formation in midgestation mouse embryos.	SOX17 ESAM	4.32e-05	4	94	2	32891959
Pubmed	Neutrophils establish rapid and robust WAVE complex polarity in an actin-dependent fashion.	ABI1 WASF2	4.32e-05	4	94	2	19200726
Pubmed	KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.	FOXN1 KMT2D	4.32e-05	4	94	2	36525973
Pubmed	The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery.	ABI1 WASF2	4.32e-05	4	94	2	17664349
Pubmed	An interaction between U2AF 65 and CF I(m) links the splicing and 3' end processing machineries.	CPSF6 CPSF7	4.32e-05	4	94	2	17024186
Pubmed	Accelerating the tempo of the segmentation clock by reducing the number of introns in the Hes7 gene.	UNCX HES7	4.32e-05	4	94	2	23219549
Pubmed	Hes7 3'UTR is required for somite segmentation function.	UNCX HES7	4.32e-05	4	94	2	25248974
Pubmed	Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells.	ABI1 WASF2	4.32e-05	4	94	2	18044991
Pubmed	Membrane targeting of WAVE2 is not sufficient for WAVE2-dependent actin polymerization: a role for IRSp53 in mediating the interaction between Rac and WAVE2.	ABI1 WASF2	4.32e-05	4	94	2	18198193
Pubmed	Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation.	ABI1 WASF2	4.32e-05	4	94	2	14765121
Pubmed	Binding of PTEN to specific PDZ domains contributes to PTEN protein stability and phosphorylation by microtubule-associated serine/threonine kinases.	MAST2 MAST3	4.32e-05	4	94	2	15951562
Pubmed	Essential role for Abi1 in embryonic survival and WAVE2 complex integrity.	ABI1 WASF2	4.32e-05	4	94	2	21482783
Pubmed	Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock.	UNCX HES7	4.32e-05	4	94	2	12783854
Pubmed	Instability of Hes7 protein is crucial for the somite segmentation clock.	UNCX HES7	4.32e-05	4	94	2	15170214
Pubmed	The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.	ABI1 WASF2	4.32e-05	4	94	2	26428302
Pubmed	Functional Interactions between BM88/Cend1, Ran-binding protein M and Dyrk1B kinase affect cyclin D1 levels and cell cycle progression/exit in mouse neuroblastoma cells.	DYRK1B RANBP9	4.32e-05	4	94	2	24312406
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	MAP7D1 ABI1 CPSF6 DROSHA WASF2 MATR3 FIP1L1 PRRC2A CPSF7	4.46e-05	615	94	9	31048545
Pubmed	Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development.	UNCX HES7 SCX	4.75e-05	26	94	3	19590010
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	PRR12 CASC3 INTS5 MAP7D1 ABI1 CPSF6 DROSHA WASF2 SLC35E1 TAF4 CTNND2 SPEN PRRC2A SF3A2	4.89e-05	1497	94	14	31527615
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	NHSL1 PRAM1 AAAS CPSF6 FIP1L1 SF3A2	5.58e-05	245	94	6	35652658
Pubmed	The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.	PRR12 CPSF6 BICRA FBRS FBRSL1	5.99e-05	152	94	5	38360978
Pubmed	Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.	FOXD4L4 FOXD4L6 FOXD4L5	6.64e-05	29	94	3	22972626
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PRR12 MAP7D1 PRCC DROSHA WASF2 FBRSL1 SLC35E1 SCRIB MAST2	6.82e-05	650	94	9	38777146
Pubmed	Rac interacts with Abi-1 and WAVE2 to promote an Arp2/3-dependent actin recruitment during chlamydial invasion.	ABI1 WASF2	7.19e-05	5	94	2	17501982
Pubmed	Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors.	CPSF6 CPSF7	7.19e-05	5	94	2	8626397
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	INF2 PRCC CPSF6 FIP1L1 CPSF7	8.34e-05	163	94	5	22113938
Pubmed	Genome-wide association study of lung function decline in adults with and without asthma.	PCDH15 CNTLN CTNND2	8.96e-05	32	94	3	22424883
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	SHANK1 INTS5 AAAS FHOD1 MATR3 IQSEC2 FBRS SLC35E1 FGFRL1 KMT2E SF3A2 CPSF7	9.73e-05	1203	94	12	29180619
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	PRR12 INTS5 DROSHA MATR3 FIP1L1 IRF2BPL PRRC2A SF3A2 WDR62 CPSF7	9.96e-05	847	94	10	35850772
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	COL4A4 NHSL1 NAT8L INF2 SKOR2 IQSEC2 IRF2BPL TAF4 MAST2	1.06e-04	689	94	9	36543142
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	PRR12 KMT2D BICRA DYRK1B FBRS FBRSL1 KDM4B	1.06e-04	398	94	7	35016035
Pubmed	Serine/threonine kinase Mirk/Dyrk1B is an inhibitor of epithelial cell migration and is negatively regulated by the Met adaptor Ran-binding protein M.	DYRK1B RANBP9	1.08e-04	6	94	2	14500717
Pubmed	Requirements for F-BAR proteins TOCA-1 and TOCA-2 in actin dynamics and membrane trafficking during Caenorhabditis elegans oocyte growth and embryonic epidermal morphogenesis.	ABI1 WASF2	1.08e-04	6	94	2	19798448
Pubmed	Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export.	CPSF6 CPSF7	1.08e-04	6	94	2	19864460
Pubmed	Intronic delay is essential for oscillatory expression in the segmentation clock.	UNCX HES7	1.08e-04	6	94	2	21300886
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXN1 MAP7D1 KMT2D ABI1 WASF2 FIP1L1 MSH3 SCRIB SPEN NOTCH3	1.10e-04	857	94	10	25609649
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	PITPNM2 CASC3 AAAS PRCC CPSF6 DROSHA IQSEC2 FBRS FBRSL1 FIP1L1 FBLIM1	1.14e-04	1038	94	11	26673895
Interaction	NCK2 interactions	PRR16 NHSL1 SH3PXD2B ABI1 CPSF6 WASF2 NR5A1 SCX PRRC2A SF3A2 KCTD17 CPSF7	2.02e-09	262	90	12	int:NCK2
Interaction	TOP3B interactions	CNPPD1 PITPNM2 PHLDB3 PRR12 NHSL1 SPHK2 SH3PXD2B INTS5 KMT2D INF2 BICRA CASKIN1 FBRS FBRSL1 FGFRL1 NLGN2 MSH3 ZFPM1 SNAPC4 MAST2 SPEN PRRC2A	3.56e-07	1470	90	22	int:TOP3B
Interaction	PRMT2 interactions	SHANK1 FHOD1 IQSEC2 FIP1L1 PRRC2A CPSF7	3.29e-06	91	90	6	int:PRMT2
Interaction	TLE3 interactions	PRR12 KMT2D TLX3 FBRS FBRSL1 TAF4 EN1 SPEN CPSF7 ALG13	6.89e-06	376	90	10	int:TLE3
Interaction	NFIX interactions	PRR12 FOXN1 KMT2D BICRA TLX3 SOX17 TAF4 SPEN	8.03e-06	227	90	8	int:NFIX
Interaction	KLF8 interactions	PRR12 MAP7D1 KMT2D BICRA FBRS FBRSL1 TAF4 SPEN PRRC2A	1.63e-05	329	90	9	int:KLF8
Interaction	ALG13 interactions	PRR12 KMT2D CPSF6 FBRS PRRC2A CPSF7 ALG13	1.80e-05	183	90	7	int:ALG13
Interaction	KIAA0232 interactions	NAT8L DYRK1B FGFRL1 FOXD4L6 SNAPC4	2.01e-05	74	90	5	int:KIAA0232
Interaction	YWHAB interactions	NHSL1 CASC3 MAP7D1 CPSF6 WASF2 MATR3 IQSEC2 RANBP9 SLAIN1 SCRIB CNTLN MAST2 WDR62 MAST3 AGAP2	4.00e-05	1014	90	15	int:YWHAB
Interaction	NFIB interactions	PRR12 KMT2D TLX3 FBRS SOX17 EN1	4.21e-05	142	90	6	int:NFIB
Interaction	DAZL interactions	CASC3 CPSF6 FBRSL1 PRRC2A CPSF7 ALG13	4.74e-05	145	90	6	int:DAZL
Interaction	VASP interactions	NHSL1 ABI1 INF2 WASF2 FHOD1 FBLIM1 WDR62 ALG13	5.13e-05	294	90	8	int:VASP
Interaction	ERG interactions	PRR12 KMT2D BICRA MATR3 FBRS FBRSL1 MSH3	6.34e-05	223	90	7	int:ERG
Interaction	SHANK3 interactions	SHANK1 SH3PXD2B ABI1 WASF2 CASKIN1 IQSEC2 NLGN2 LMTK3 NOTCH3 AGAP2	7.32e-05	496	90	10	int:SHANK3
Interaction	SOX9 interactions	PRR12 KMT2D NR5A1 SPEN SCX	7.40e-05	97	90	5	int:SOX9
Interaction	FBRS interactions	TLX3 FBRS SOX17 KCTD17 ALG13	9.40e-05	102	90	5	int:FBRS
Interaction	PQBP1 interactions	CPSF6 TLX3 SF3A2 AGAP2 CPSF7	1.08e-04	105	90	5	int:PQBP1
Interaction	KMT2D interactions	KMT2D TLX3 SOX17 EN1 KDM4B ALG13	1.11e-04	169	90	6	int:KMT2D
Interaction	RNPS1 interactions	CASC3 CPSF6 BICRA RANBP9 FIP1L1 SCRIB TAF4 SF3A2 CPSF7	1.18e-04	425	90	9	int:RNPS1
Interaction	FMR1 interactions	CASC3 CASKIN1 MATR3 IQSEC2 RANBP9 SCRIB LMTK3 PRRC2A AGAP2 ALG13	1.38e-04	536	90	10	int:FMR1
Interaction	CRX interactions	PRR12 KMT2D BICRA TLX3 FBRS FBRSL1 SPEN	1.43e-04	254	90	7	int:CRX
Interaction	TBXT interactions	PRR12 KMT2D FBRS FBRSL1 SPEN	1.72e-04	116	90	5	int:TBXT
Interaction	FANCD2OS interactions	DYRK1B FBRS FBRSL1	2.08e-04	26	90	3	int:FANCD2OS
Interaction	NCOR1 interactions	PRAM1 MATR3 TLX3 SOX17 EN1 SPEN KDM4B ALG13	2.20e-04	363	90	8	int:NCOR1
Interaction	GRB2 interactions	CASC3 SH3PXD2B CPSF6 WASF2 FHOD1 FIP1L1 PRR22 PRRC2A SF3A2 SLX1A CPSF7 SOS2	2.41e-04	806	90	12	int:GRB2
Interaction	RING1 interactions	TLX3 FBRS FBRSL1 EN1 MN1 ALG13	2.84e-04	201	90	6	int:RING1
Interaction	PAX9 interactions	PRR12 KMT2D FBRS FBRSL1 SLAIN1	2.93e-04	130	90	5	int:PAX9
Interaction	FEV interactions	PRR12 KMT2D BICRA FBRS FBRSL1 TAF4	2.99e-04	203	90	6	int:FEV
Interaction	TNIK interactions	SHANK1 ABI1 MATR3 IQSEC2 RANBP9 NLGN2 CTNND2 AGAP2	3.05e-04	381	90	8	int:TNIK
Interaction	KMT2C interactions	KMT2D TLX3 SOX17 EN1 KDM4B	3.37e-04	134	90	5	int:KMT2C
Interaction	PCGF1 interactions	PRAM1 TLX3 FBRS SOX17 EN1 ALG13	3.41e-04	208	90	6	int:PCGF1
Interaction	NFIC interactions	PRR12 KMT2D TLX3 FBRS SOX17 FBRSL1	3.59e-04	210	90	6	int:NFIC
Interaction	RCOR1 interactions	PHLDB3 MAP7D1 KMT2D MATR3 TLX3 FBRS RANBP9 SPEN WDR62	3.61e-04	494	90	9	int:RCOR1
Interaction	CEBPA interactions	PRR12 PRAM1 MAP7D1 KMT2D UNCX CPSF6 BICRA MATR3 FIP1L1 TAF4 DBP SPEN PRRC2A SF3A2 CPSF7	3.85e-04	1245	90	15	int:CEBPA
Interaction	P4HA2 interactions	MAP7D1 CPSF6 FIP1L1 PRRC2A WDR62	3.86e-04	138	90	5	int:P4HA2
Interaction	BCOR interactions	TLX3 FBRS SOX17 FBRSL1 SNAPC4 EN1 ALG13	4.09e-04	302	90	7	int:BCOR
Interaction	HOMER3 interactions	ABI1 PRCC WASF2 SOX17 SLAIN1	4.12e-04	140	90	5	int:HOMER3
Interaction	SP7 interactions	PRR12 KMT2D PRCC BICRA FBRS FBRSL1 CPSF7	4.25e-04	304	90	7	int:SP7
Interaction	EP300 interactions	CASC3 KMT2D PRCC CPSF6 MATR3 TLX3 DYRK1B FIP1L1 PLAGL1 SCRIB DBP EN1 MN1 SF3A2 CPSF7 ALG13	4.36e-04	1401	90	16	int:EP300
Interaction	PFN1 interactions	NHSL1 ABI1 INF2 CPSF6 WASF2 FHOD1 RANBP9 WDR62 ALG13	4.49e-04	509	90	9	int:PFN1
Cytoband	9q21.11	FOXD4L4 FOXD4L6 FOXD4L5	3.24e-05	30	94	3	9q21.11
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	SHANK1 PHLDB3 PRR12 SPHK2 BICRA DYRK1B MAMSTR DBP LMTK3 WDR62	1.69e-04	1192	94	10	chr19q13
Cytoband	19q13.3	SHANK1 BICRA DBP	6.55e-04	82	94	3	19q13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	PRAM1 SLC35E1 PRR22 SF3A2 NOTCH3 KDM4B MAST3	1.28e-03	797	94	7	chr19p13
Cytoband	19q13.33	PRR12 MAMSTR LMTK3	1.38e-03	106	94	3	19q13.33
Cytoband	12q14.1	MARCHF9 AGAP2	1.51e-03	28	94	2	12q14.1
GeneFamily	PDZ domain containing	SHANK1 SCRIB MAST2 MAST3	1.02e-03	152	53	4	1220
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PHLDB3 PSD AGAP2 SOS2	3.10e-03	206	53	4	682
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2D KMT2E	4.45e-03	34	53	2	487
GeneFamily	Tudor domain containing	KDM4B ALG13	5.26e-03	37	53	2	780
GeneFamily	Ankyrin repeat domain containing	SHANK1 CASKIN1 NOTCH3 AGAP2	5.49e-03	242	53	4	403
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	TIE1 LMTK3	6.12e-03	40	53	2	321
CoexpressionAtlas	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0	CNPPD1 PRR12 SPHK2 DROSHA MARCHF9 DYRK1B FGFRL1 SLAIN1 IRF2BPL SCRIB DBP CTNND2 LMTK3 FBLIM1 PRRC2A NOTCH3 KCTD17	1.39e-05	1275	87	17	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASC3 NAT8L PRAM1 FBRS CAMTA2	1.56e-05	148	94	5	b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASC3 NAT8L PRAM1 FBRS CAMTA2	1.56e-05	148	94	5	ba277c898678dd36f8dc1d681301c71901b89055
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHLDB3 NHSL1 HES7 CAMTA2 SOS2	2.07e-05	157	94	5	8c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHLDB3 NHSL1 HES7 CAMTA2 SOS2	2.07e-05	157	94	5	ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHLDB3 NHSL1 HES7 CAMTA2 SOS2	2.07e-05	157	94	5	008f938a338f43c3251dcac574f1b4f689926c71
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	INF2 ESAM SCRIB WDR62 SOS2	3.21e-05	172	94	5	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	facs-Skin-nan-24m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN1 NAT8L SPHK2 UNCX NOTCH3	3.21e-05	172	94	5	5ca89af7406e7e1a055dd60d6f89615f69e62324
ToppCell	E15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TIE1 VSTM2L SOX17 ESAM FBLIM1	3.30e-05	173	94	5	b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell	wk_15-18-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 NHSL1 NAT8L KMT2D SLC35E1	4.54e-05	185	94	5	636505a3d96f75d951ab42bcf8af6ae07abc732d
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRR16 HES7 ESAM NOTCH3 AGAP2	4.78e-05	187	94	5	150023e6a50c9da461f2321074d2d5e96caafb06
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TIE1 SOX17 ESAM CTNND2	4.91e-05	188	94	5	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	LV-14._Fibroblast_III\|World / Chamber and Cluster_Paper	PHLDB3 COL4A4 SH3PXD2B MN1 ALG13	5.03e-05	189	94	5	3922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRR16 SH3PXD2B TIE1 SOX17 ESAM	5.03e-05	189	94	5	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TIE1 SOX17 ESAM CTNND2	5.03e-05	189	94	5	e82211b9dc7540e7a183be2cbcfae39fdf503949
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TIE1 SOX17 ESAM CTNND2	5.16e-05	190	94	5	a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TIE1 SOX17 ESAM CTNND2	5.16e-05	190	94	5	106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TIE1 SOX17 ESAM CTNND2	5.42e-05	192	94	5	0aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SHANK1 PRAM1 VSTM2L CTNND2 SCX	5.42e-05	192	94	5	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	TCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PITPNM2 MAMSTR FGFRL1 PLAGL1 NR5A1	5.56e-05	193	94	5	c0d4da15d973cf6f8daa2b0af84b1baaf8491b83
ToppCell	LV-14._Fibroblast_III\|LV / Chamber and Cluster_Paper	PHLDB3 COL4A4 SH3PXD2B MN1 ALG13	5.69e-05	194	94	5	927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCell	TCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PITPNM2 AAAS MAMSTR FGFRL1 NR5A1	5.83e-05	195	94	5	c3280bb6219e2eff5e24ef45aa2d76479a562122
ToppCell	10x5'v1-week_12-13-Endothelial-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NHSL1 TIE1 SOX17 ESAM FBLIM1	6.27e-05	198	94	5	122215d9288533ad03562cf777e846504863df9a
ToppCell	10x5'v1-week_12-13-Endothelial\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NHSL1 TIE1 SOX17 ESAM FBLIM1	6.27e-05	198	94	5	307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	VSTM2L SLAIN1 NLGN2 KDM4B MAST3	6.58e-05	200	94	5	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN1 VSTM2L SOX17 NR5A1	2.03e-04	137	94	4	b831d917f5073ccff158662adb281d34f023126a
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN1 VSTM2L SOX17 NR5A1	2.03e-04	137	94	4	cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN1 VSTM2L SOX17 NR5A1	2.03e-04	137	94	4	5d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L UNCX TLX3 FBLIM1	2.09e-04	138	94	4	6b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCell	Mild/Remission-B_naive-13\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MAMSTR ESAM NLGN2 PRR7	2.33e-04	142	94	4	49873a2d9b1ae4bdbf253d1c09bf8845cc0cc917
ToppCell	Mild/Remission-B_naive-13\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MAMSTR ESAM NLGN2 PRR7	2.52e-04	145	94	4	7827aef87f834cd0d19780417757c9386e19b22e
ToppCell	facs-Heart-RA-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 ESAM EN1 KRTAP4-16	2.59e-04	146	94	4	d903e091a917d3f5dcf82107e636520f75e47403
ToppCell	facs-Heart-RA-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX17 ESAM EN1 KRTAP4-16	2.59e-04	146	94	4	9c9218e5257253597f2fd74fbd589b962d3078a3
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L PRAM1 AAAS PRR7	2.87e-04	150	94	4	34774b015adecc2be56a471fda8994e89a6ad93e
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRR16 COL4A4 DBP SCX	2.87e-04	150	94	4	4bdcdce40f54580c7a4e1416b468e657ba8874fc
ToppCell	3'_v3-blood-Lymphocytic_T_CD8-Trm_gut_CD8\|blood / Manually curated celltypes from each tissue	SH3PXD2B PSD SCX PRR7	3.02e-04	152	94	4	1fea735321da6db6d2cd3f83d2f7fac72d44904d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHANK1 SOX17 FIP1L1 CTNND2	3.17e-04	154	94	4	1899138c096c08d8aee6b1970b7c0081e14c88a8
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRR16 INF2 ZFPM1 MAST3	3.58e-04	159	94	4	a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	INTS5 INF2 SLC35E1 PRR22	3.58e-04	159	94	4	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TIE1 SOX17 ESAM MN1	3.93e-04	163	94	4	1feb4ef7b8abcfca9a72c8d13c40548de79e7db2
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHANK1 PRAM1 HES7 NR5A1	3.93e-04	163	94	4	00e791358a7eb6c3e95f87afe22153845012e4a1
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	INTS5 MATR3 DYRK1B NLGN2	4.21e-04	166	94	4	f62db9d9b6c9dd8f2afcaea0fc5f8c69f50205b2
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TIE1 SOX17 ESAM LMTK3	4.40e-04	168	94	4	55c9de7b3a1d6cf7b02b020ff92ab4ede8d195cc
ToppCell	facs-Heart-RV-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 INF2 SOX17 ESAM	4.40e-04	168	94	4	831b000e26b4a7e7fdfa3988372e0281c45eadbb
ToppCell	Adult-Endothelial-endothelial_cell_of_vein-D175\|Adult / Lineage, Cell type, age group and donor	SHANK1 MAMSTR ESAM FBLIM1	4.50e-04	169	94	4	e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 MAMSTR NLGN2	4.60e-04	170	94	4	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 MAMSTR NLGN2	4.60e-04	170	94	4	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 MAMSTR NLGN2	4.60e-04	170	94	4	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB3 SH3PXD2B VSTM2L CNTLN	4.92e-04	173	94	4	a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHLDB3 SH3PXD2B VSTM2L CNTLN	4.92e-04	173	94	4	639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell	droplet-Fat-Scat-21m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM2 TIE1 SOX17 ESAM	4.92e-04	173	94	4	f13124b4cf2ac1dc2895f90f5487d6ac681b0ba4
ToppCell	droplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TIE1 FHOD1 HES7 SOX17	4.92e-04	173	94	4	66488d01e03264fb193285470901c9c4182fbae8
ToppCell	droplet-Heart-4Chambers-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 ESAM PLAGL1 ZFPM1	4.92e-04	173	94	4	9a04271c51fae34f547db3206f9ff5857686e45c
ToppCell	droplet-Mammary_Gland-nan-3m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 MAMSTR ESAM	4.92e-04	173	94	4	fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PITPNM2 TIE1 SOX17 ESAM	5.03e-04	174	94	4	b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell	wk_20-22-Hematologic_Lymphocytic-T_&_ILC-ILCP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SHANK1 COL4A4 PRAM1 CTNND2	5.03e-04	174	94	4	5e6050d20a5b27640f6a200441125b8ceba123c8
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L TIE1 SOX17 ESAM	5.03e-04	174	94	4	fa6eb451555766398996bbe8f555a3f4c0f3c108
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L TIE1 SOX17 ESAM	5.03e-04	174	94	4	1f5b0fa58b2a7335667357af7e50e5242cd13d7d
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TIE1 FHOD1 SOX17 ESAM	5.03e-04	174	94	4	42735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L TIE1 SOX17 ESAM	5.03e-04	174	94	4	ac3aee6ed49d1c421f33509e3ffc5cb17750a473
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Neuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	FBRSL1 IRF2BPL NLGN2 PRRC2A	5.13e-04	175	94	4	2812ac2ef41d245db544697fb6da1883361c96e8
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD CTNND2 MAST3 AGAP2	5.13e-04	175	94	4	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	droplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 MAMSTR ESAM	5.25e-04	176	94	4	5386386619cf173939d3c117b20e6f27ab397993
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 INF2 SOX17 ESAM	5.25e-04	176	94	4	eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCell	droplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 MAMSTR ESAM	5.25e-04	176	94	4	820edade963768e4bfd86b554da4cd7100567ac8
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 ESAM PRR22 MN1	5.25e-04	176	94	4	c4d9166e5bbb7ca544107db14e4374289f5de6bd
ToppCell	droplet-Kidney-KIDNEY-30m-Endothelial-kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 ESAM PRR22 MN1	5.25e-04	176	94	4	d58ef51002ea50b3037636038214bbb7454cb503
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	PRR12 TIE1 ESAM PLAGL1	5.36e-04	177	94	4	6da88c358b3a2e47fa3472217a38b6b00ad7b280
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-LTi-like_NCR+_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SHANK1 COL4A4 PRAM1 SCX	5.47e-04	178	94	4	0b59e3d75b143bd7bf91a7800a49699c51e68c5a
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNM2 TIE1 SOX17 ESAM	5.47e-04	178	94	4	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	droplet-Heart-4Chambers-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 FHOD1 SOX17 ESAM	5.47e-04	178	94	4	93ce73f8bcec63ebf86fabb546f88400e8f06465
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	NAT8L SPHK2 TAF4 DBP	5.59e-04	179	94	4	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	facs-Heart-RV-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 INF2 SOX17 ESAM	5.59e-04	179	94	4	6aa211670e5d6e013d0980967aa0a4f8f2905efe
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TIE1 MAMSTR WDR62 SOS2	5.59e-04	179	94	4	06d412fc096d88de168969466ce422f0ab5553b2
ToppCell	367C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TIE1 VSTM2L ESAM KCTD17	5.59e-04	179	94	4	5aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCell	facs-Heart-RV-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 INF2 SOX17 ESAM	5.59e-04	179	94	4	cf4d3828a3ce97932c68d06f5c65a070fc6d832c
ToppCell	facs-Heart-RV-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 INF2 SOX17 ESAM	5.59e-04	179	94	4	f9bc76ff25f88ee44c72499a0df9dc16f519c4cb
ToppCell	10x5'-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	NHSL1 SH3PXD2B CNTLN NOTCH3	5.71e-04	180	94	4	7be7d7a6906fff6dbdecd9cb013d855aba4eda2a
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L PSD CASKIN1 NOTCH3	5.71e-04	180	94	4	a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NAT8L PSD CASKIN1 NOTCH3	5.71e-04	180	94	4	63a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCell	facs-Heart-RA-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 ESAM PLAGL1	5.71e-04	180	94	4	174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TIE1 ESAM CTNND2	5.71e-04	180	94	4	30cf3c7ee29694eaccb89bf8053a82037d5c9f1d
ToppCell	IPF-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	PITPNM2 NHSL1 PRAM1 VSTM2L	6.07e-04	183	94	4	9b507547e6adf78e46e7f542cd9958224ec5826a
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte-2\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX PLAGL1 DBP SCX	6.20e-04	184	94	4	e123ad8ee46a032825a0bd4b3586ddcb3eda03d4
ToppCell	5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PITPNM2 TIE1 SOX17 ESAM	6.20e-04	184	94	4	97e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR16 PCDH15 NLGN2 CTNND2	6.20e-04	184	94	4	278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRR16 PCDH15 NLGN2 CTNND2	6.20e-04	184	94	4	8d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SHANK1 PRR16 PLAGL1 MN1	6.32e-04	185	94	4	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PITPNM2 TIE1 ESAM CTNND2	6.32e-04	185	94	4	808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NHSL1 VSTM2L DYRK1B MAMSTR	6.32e-04	185	94	4	ef3c1fd52d21d96f81fb0e5097b24be0ce16e222
ToppCell	droplet-Pancreas-Endocrine-18m-Endothelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TIE1 SOX17 ZFPM1 KCTD17	6.32e-04	185	94	4	512a195ebbae445afe3722a3943020080daf2f3c
ToppCell	Adult-Endothelial-capillary_endothelial_cell_(Cap1)-D231\|Adult / Lineage, Cell type, age group and donor	PITPNM2 TIE1 SOX17 ESAM	6.32e-04	185	94	4	07f9f38f0739d7c830641723a38385550ac1ac92
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NHSL1 VSTM2L DYRK1B MAMSTR	6.32e-04	185	94	4	c357fa098b561da16c9fa82b0c3563b5cd3fa875
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NAT8L VSTM2L LMTK3 AGAP2	6.32e-04	185	94	4	edb114487206e4e8df4c7878285df40f49b7fd64
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L3-4_RORB_RPS3P6\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRR16 NAT8L ESAM PLAGL1	6.32e-04	185	94	4	10da5c2a92bfb3248d3f6f94a0933996326cf590
ToppCell	PCW_05-06-Endothelial-Endothelial_mature-endo_bronchial_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 TIE1 SOX17 ESAM	6.45e-04	186	94	4	0cc7504297fd0c97ea50e4b3ff58fcedc4c1cfaa
ToppCell	PCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating2_(14)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PITPNM2 TIE1 SOX17 ESAM	6.45e-04	186	94	4	2cbf1aaff87cd9fba01f814a119fe86e5af82290
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NHSL1 TIE1 DBP FBLIM1	6.45e-04	186	94	4	1e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX VSTM2L TLX3 SCX	6.45e-04	186	94	4	a1ab273b01971d6a892912560d387685dd657179
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNCX VSTM2L TLX3 SCX	6.58e-04	187	94	4	ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TIE1 SOX17 ESAM PLAGL1	6.58e-04	187	94	4	6cf7be5401b81a4eeb30840fb3733d61a24af539
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	CNPPD1 FHOD1 SLC35E1 FIP1L1 MAST2 PRR7 ALG13	1.26e-05	191	92	7	1059_DN
Drug	CAY10397; Up 200; 10uM; PC3; HT_HG-U133A	CNPPD1 AAAS BICRA FBRS CAMTA2 MN1 KDM4B	1.49e-05	196	92	7	7071_UP
Drug	Sulfamethoxazole [723-46-6]; Up 200; 15.8uM; MCF7; HT_HG-U133A	CNPPD1 SPHK2 MAST2 EN1 KDM4B KCTD17 WDR62	1.49e-05	196	92	7	2296_UP
Drug	Fenbendazole [43210-67-9]; Down 200; 13.4uM; PC3; HT_HG-U133A	AAAS MAST2 EN1 MN1 SF3A2 PRR7 KCTD17	1.59e-05	198	92	7	3805_DN
Drug	Urosiol [128-13-2]; Down 200; 10.2uM; PC3; HT_HG-U133A	AAAS INF2 CPSF6 FIP1L1 EN1 MAST3 ALG13	1.59e-05	198	92	7	7243_DN
Disease	hypertensive nephropathy	COL4A4 INF2	1.31e-04	6	88	2	C0848548
Disease	Male sterility	KMT2D DROSHA NR5A1	4.02e-04	48	88	3	C0917731
Disease	Male infertility	KMT2D DROSHA NR5A1	4.02e-04	48	88	3	C0021364
Disease	Subfertility, Male	KMT2D DROSHA NR5A1	4.02e-04	48	88	3	C0848676
Disease	intracranial aneurysm (is_implicated_in)	KMT2D SOX17	5.69e-04	12	88	2	DOID:10941 (is_implicated_in)
Disease	prostate cancer (is_marker_for)	KMT2D KMT2E KDM4B AGAP2	1.24e-03	156	88	4	DOID:10283 (is_marker_for)
Disease	serum carcinoembryonic antigen measurement	DBP LMTK3	1.61e-03	20	88	2	EFO_0005760
Disease	cortical thickness	PITPNM2 NHSL1 SH3PXD2B CPSF6 TLX3 FGFRL1 MSH3 MAST2 KDM4B SOS2	1.76e-03	1113	88	10	EFO_0004840
Disease	Renal glomerular disease	COL4A4 INF2	2.14e-03	23	88	2	C0268731
Disease	Glomerulopathy Assessment	COL4A4 INF2	2.14e-03	23	88	2	C4521256
Disease	macula measurement	PITPNM2 COL4A4 DYRK1B CTNND2	2.50e-03	189	88	4	EFO_0008375
Disease	Neurodevelopmental Disorders	IQSEC2 KMT2E ALG13	2.74e-03	93	88	3	C1535926
Disease	alcohol use disorder (implicated_via_orthology)	PSD FBRS FBRSL1 NOTCH3	2.80e-03	195	88	4	DOID:1574 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
FPPAIPGLPTLLPHP	FBRSL1	501	Q9HCM7
APWDPLPGPPPVLPH	AAAS	526	Q9NRG9
IPHAGASLPPPPPPP	ALG13	911	Q9NP73
PPSPHPSPPARQLGP	CNTLN	6	Q9NXG0
PACPLLPPQPPLPDH	ARID3C	21	A6NKF2
HPGPPGVLVTPPLPL	COL4A4	351	P53420
HGAAPPIPSPPPSPP	CAMTA2	456	O94983
PSGAPPAPPLAPLLP	ABI1	281	Q8IZP0
LHPGPPAGSPPPLTL	AGAP2	281	Q99490
GHLAGPEPAPPPPPP	CTNND2	211	Q9UQB3
PPLPPPDDPATLGPH	DYRK1B	601	Q9Y463
ALLLHPPPPPPPATA	RANBP9	66	Q96S59
PRLPPHLAVPPPGAI	CPSF7	271	Q8N684
VPAITAPPTPPHPPG	PHLDB3	491	Q6NSJ2
APPTPPHPPGPRILD	PHLDB3	496	Q6NSJ2
PPAPAFPPQLPPHIA	MSH3	66	P20585
PPLSLPHPHPLRPPG	NTM-AS1	86	Q6ZSK4
PPAEPPPTDLAHLPP	CASKIN1	1196	Q8WXD9
PPTDLAHLPPLPPPE	CASKIN1	1201	Q8WXD9
PAPGILGPPPPSFHL	MATR3	351	P43243
PHPGPLLGAPAPPQP	FOXD4L4	231	Q8WXT5
IPPPPASAPPVGPHR	IQSEC2	1306	Q5JU85
PPAPPTPPHPATPGD	LMTK3	1386	Q96Q04
GSPLPHSPVFPPPPP	NHSL1	966	Q5SYE7
LPPPPPHALGSRGPP	IRF2BPL	271	Q9H1B7
CTPAPAPPLPGHRPP	FGFRL1	406	Q8N441
PPPFFPPGAPPTHLP	FIP1L1	356	Q6UN15
PPPPPGHAPAPESPR	ZFPM1	756	Q8IX07
PPPAPPGPSFLLPLA	NOTCH3	2176	Q9UM47
LLPPQLPPPPAHFPS	KDM4B	461	O94953
QTAGHHLPPPPPPPG	KMT2E	1671	Q8IZD2
LSPPLPSPPLPSPHF	KRTAP4-16	211	G5E9R7
LPAPSPTTPGPHPPA	PITPNM2	876	Q9BZ72
PPSPPAAPCLPPLAH	EN1	56	Q05925
PPPPLPAGGSRPHPL	KCTD17	261	Q8N5Z5
LPPPLPGSCEFLPPP	INF2	476	Q27J81
PPAPPLPPPGALDAL	MARCHF9	81	Q86YJ5
AGSPPGLAPPQPPPH	PRR7	66	Q8TB68
PPPPPPPPGAHLYEE	PCDH15	1436	Q96QU1
HPPNISPSACPLPPP	PCDH15	1736	Q96QU1
LPPPDPPAPPTLLHN	CNPPD1	321	Q9BV87
PPPPPAAAPGTPHLL	FBRS	411	Q9HAH7
PYAPGALPPPPPPHL	CASC3	636	O15234
LGPPLTLAPPPHLPG	CPSF6	331	Q16630
TLAPPPHLPGPPPGA	CPSF6	336	Q16630
PPPGAPPPAPHVNPA	CPSF6	346	Q16630
PPHGPPRPGALTPTP	ESAM	321	Q96AP7
CPSPGPGHTLPPKPP	MAP7D1	481	Q3KQU3
IPLSPLAHTPSPPPP	MAST2	1341	Q6P0Q8
APPPRSPSPLPGHPP	MAST3	1196	O60307
CPPGVPSPSPPPHKL	MAMSTR	151	Q6ZN01
LHLSPPPPPPQAPAE	FBLIM1	136	Q8WUP2
AFLLEHGLPPSPPPP	DBP	121	Q10586
PPPLPLAAPLPHSVP	FHOD1	601	Q9Y613
APLTGLLPPPPPPHR	HES7	191	Q9BYE0
LLPPPPPPHRQDGAP	HES7	196	Q9BYE0
SQPPEGPLPPAPHLP	BICRA	866	Q9NZM4
LHPFGPFPPPPPTAT	NLGN2	806	Q8NFZ4
CGPHDPSLAPPPPPG	MN1	656	Q10571
HPAGPPTAAPAVPPP	TAF4	286	O00268
GPLPPCPIRPPFPNH	DROSHA	91	Q9NRR4
HPPGPGQPSPPPEAL	SOX17	326	Q9H6I2
PPPPAPDYVLPPSLH	NR5A1	131	Q13285
HPSVSPGSPPPPLPN	PLAGL1	286	Q9UM63
FDGPLHSPPPPPPRD	SOS2	1196	Q07890
PAPRPGPLPGPHPSL	PSD	331	A5PKW4
AFPPPLLLPPPTGDP	PRCC	61	Q92733
LHLSPGLAPPGPPQP	FOXN1	456	O15353
PHPGPLLGAPAPPQP	FOXD4L5	231	Q5VV16
PHPGPLLGAPAPPQP	FOXD4L6	231	Q3SYB3
HQGPPLPPTPHLPPF	PRR16	246	Q569H4
PASSLGHPPAKPPLP	PRAM1	446	Q96QH2
GHPPAKPPLPPGPVD	PRAM1	451	Q96QH2
PPAPPPLSLLPVGPA	PRRC2A	2001	P48634
APHLLLLPPPPPAAP	SLAIN1	56	Q8ND83
PQPHGPLASSPPPPD	SPATA31E1	246	Q6ZUB1
GGPLPPSPLPHSSPP	SCRIB	951	Q14160
PVAGPPHLRPPPPSH	INTS5	96	Q6P9B9
ASAQPPPPPPPAHAL	PRR12	296	Q9ULL5
PPATPAVPHPPPSGA	PRR12	1326	Q9ULL5
PGPSPHPSSGPLLPP	SLC35E1	91	Q96K37
PGVHPPAPGVHPPAP	SF3A2	306	Q15428
PAPGVHPPAPGVHPP	SF3A2	311	Q15428
PPAPGVHPPAPGVHP	SF3A2	331	Q15428
PGVHPPAPGVHPPAP	SF3A2	341	Q15428
PAPGVHPPAPGVHPP	SF3A2	346	Q15428
PGPPHPLPDTPAPAT	SHANK1	1586	Q9Y566
HPPGPPAPAAPAPAA	SHANK1	1646	Q9Y566
LPPLLPPPFPGDPAH	C11orf53	86	Q8IXP5
PPHPGPPATNTPAPI	PRR22	366	Q8IZ63
PVPVPLPAPAPAPHG	SPEN	3251	Q96T58
PDHLLPPLGTPLPPD	SPHK2	516	Q9NRA0
ASPPAHVLLPPSGPP	TIE1	631	P35590
EPLPPKPGPGSPSHP	SH3PXD2B	281	A1X283
LPAPRPPGPHASPVP	PPM1M	16	Q96MI6
LLGPHLLGAPPPPPP	SKOR2	276	Q2VWA4
PAHRPLPGAVPPPLP	TLX3	91	O43711
SPSHPPPAPPLGSPP	WASF2	296	Q9Y6W5
PSLPAPESPGLPAHP	WDR62	1341	O43379
LCLPPPPHVPLAFGP	SLX1A	141	Q9BQ83
PPHVPLAFGPPPPQA	SLX1A	146	Q9BQ83
PPLPHTPHGRPAPGP	SNAPC4	931	Q5SXM2
LHLPEAPPAAPAPPP	VSTM2L	171	Q96N03
HAARAGSPPPPPPPP	SCX	151	Q7RTU7
QPLPPSPSPGPHARP	PRR23C	231	Q6ZRP0
PPEPPPPAAKGPGAH	UNCX	246	A6NJT0
SLKPPVPQPGLPPPH	KMT2D	2546	O14686
APPAPPPAPVAQPHG	NAT8L	51	Q8N9F0
PGDPTPPSPLPPAHV	NEXN-AS1	166	Q8NBZ9
PPSPLPPAHVPPTLL	NEXN-AS1	171	Q8NBZ9