Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	bitter taste receptor activity	TAS2R13 TAS2R33 TAS2R36 TAS2R31 TAS2R43 TAS2R20 TAS2R46	8.79e-12	27	78	7	GO:0033038
GeneOntologyMolecularFunction	taste receptor activity	TAS2R13 TAS2R33 TAS2R36 TAS2R31 TAS2R43 TAS2R20 TAS2R46	4.15e-11	33	78	7	GO:0008527
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC9A4 TPCN2 NOX5 TSPO2 TMEM63C LRRC8A KCNQ3 ABCC9 SLC5A12 SLC35F1 TMC5 SLC2A12 SLC4A11 CYB5A TMEM63A	4.44e-05	1180	78	15	GO:0022857
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC9A4 TPCN2 NOX5 TMEM63C LRRC8A KCNQ3 ABCC9 SLC5A12 TMC5 SLC4A11 CYB5A TMEM63A	5.53e-05	793	78	12	GO:0015075
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	TAS2R13 TAS2R33 TAS2R36 SCARB2 MRGPRF TMEM63C NTSR2 ABCC9 TAS2R31 TAS2R43 TAS2R20 TAS2R46 ADGRE2 F2RL1 OR6B2 TMEM63A	5.66e-05	1353	78	16	GO:0004888
GeneOntologyMolecularFunction	monoatomic ion channel activity	TPCN2 NOX5 TMEM63C LRRC8A KCNQ3 ABCC9 TMC5 SLC4A11 TMEM63A	7.42e-05	459	78	9	GO:0005216
GeneOntologyMolecularFunction	transporter activity	SLC9A4 TPCN2 NOX5 TSPO2 TMEM63C LRRC8A KCNQ3 ABCC9 SLC5A12 SLC35F1 TMC5 SLC2A12 SLC4A11 CYB5A TMEM63A	1.20e-04	1289	78	15	GO:0005215
GeneOntologyMolecularFunction	osmolarity-sensing monoatomic cation channel activity	TMEM63C TMEM63A	1.49e-04	5	78	2	GO:1990760
GeneOntologyMolecularFunction	G protein-coupled receptor activity	TAS2R13 TAS2R33 TAS2R36 MRGPRF NTSR2 TAS2R31 TAS2R43 TAS2R20 TAS2R46 ADGRE2 F2RL1 OR6B2	1.55e-04	884	78	12	GO:0004930
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC9A4 TPCN2 NOX5 TMEM63C KCNQ3 ABCC9 SLC5A12 SLC4A11 CYB5A TMEM63A	1.60e-04	627	78	10	GO:0022890
GeneOntologyMolecularFunction	channel activity	TPCN2 NOX5 TMEM63C LRRC8A KCNQ3 ABCC9 TMC5 SLC4A11 TMEM63A	2.04e-04	525	78	9	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	TPCN2 NOX5 TMEM63C LRRC8A KCNQ3 ABCC9 TMC5 SLC4A11 TMEM63A	2.07e-04	526	78	9	GO:0022803
GeneOntologyMolecularFunction	osmosensor activity	TMEM63C TMEM63A	2.24e-04	6	78	2	GO:0005034
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC9A4 TPCN2 NOX5 TMEM63C KCNQ3 ABCC9 SLC5A12 SLC4A11 CYB5A TMEM63A	2.53e-04	664	78	10	GO:0008324
GeneOntologyMolecularFunction	heme binding	DUOX1 NOX5 CYP8B1 FA2H CYB5A	3.43e-04	154	78	5	GO:0020037
GeneOntologyMolecularFunction	monoatomic cation channel activity	TPCN2 NOX5 TMEM63C KCNQ3 ABCC9 SLC4A11 TMEM63A	3.86e-04	343	78	7	GO:0005261
GeneOntologyMolecularFunction	tetrapyrrole binding	DUOX1 NOX5 CYP8B1 FA2H CYB5A	4.58e-04	164	78	5	GO:0046906
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	6.64e-04	10	78	2	GO:0001849
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC9A4 TPCN2 NOX5 TMEM63C KCNQ3 ABCC9 SLC5A12 SLC4A11 CYB5A TMEM63A	7.15e-04	758	78	10	GO:0015318
GeneOntologyMolecularFunction	superoxide-generating NAD(P)H oxidase activity	DUOX1 NOX5	9.69e-04	12	78	2	GO:0016175
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	FADS6 CYB5A	1.14e-03	13	78	2	GO:0016717
GeneOntologyMolecularFunction	gated channel activity	TPCN2 TMEM63C KCNQ3 ABCC9 TMC5 TMEM63A	1.96e-03	334	78	6	GO:0022836
GeneOntologyMolecularFunction	ligand-gated monoatomic cation channel activity	TPCN2 TMEM63C ABCC9 TMEM63A	2.21e-03	140	78	4	GO:0099094
GeneOntologyMolecularFunction	mechanosensitive monoatomic ion channel activity	TMC5 TMEM63A	2.21e-03	18	78	2	GO:0008381
GeneOntologyMolecularFunction	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	DUOX1 NOX5	2.73e-03	20	78	2	GO:0050664
GeneOntologyMolecularFunction	opsonin binding	C4A C4B	4.26e-03	25	78	2	GO:0001846
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC9A4 TPCN2 SLC5A12 SLC4A11	4.53e-03	171	78	4	GO:0015081
GeneOntologyMolecularFunction	calcium-activated cation channel activity	TMEM63C TMEM63A	4.96e-03	27	78	2	GO:0005227
GeneOntologyMolecularFunction	proton channel activity	NOX5 SLC4A11	4.96e-03	27	78	2	GO:0015252
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of bitter taste	TAS2R13 TAS2R33 TAS2R36 TAS2R31 TAS2R43 TAS2R20 TAS2R46	2.62e-10	44	77	7	GO:0001580
GeneOntologyBiologicalProcess	sensory perception of bitter taste	TAS2R13 TAS2R33 TAS2R36 TAS2R31 TAS2R43 TAS2R20 TAS2R46	4.98e-10	48	77	7	GO:0050913
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of taste	TAS2R13 TAS2R33 TAS2R36 TAS2R31 TAS2R43 TAS2R20 TAS2R46	6.71e-10	50	77	7	GO:0050912
GeneOntologyBiologicalProcess	sensory perception of taste	TAS2R13 TAS2R33 TAS2R36 TAS2R31 TAS2R43 TAS2R20 TAS2R46	7.59e-09	70	77	7	GO:0050909
GeneOntologyBiologicalProcess	import into cell	DOCK1 SLC9A4 TPCN2 TSPO2 SCARB2 LRRC8A KCNQ3 ABCC9 C4A C4B SNX33 XKR6 TAFA4 MYO15A F2RL1 LYST VEGFA	3.40e-07	1074	77	17	GO:0098657
GeneOntologyBiologicalProcess	endocytosis	DOCK1 TPCN2 SCARB2 KCNQ3 C4A C4B SNX33 XKR6 TAFA4 MYO15A F2RL1 LYST VEGFA	1.08e-05	827	77	13	GO:0006897
GeneOntologyBiologicalProcess	superoxide anion generation	DUOX1 NOX5 TAFA4 F2RL1	3.63e-05	50	77	4	GO:0042554
GeneOntologyBiologicalProcess	phagocytosis	DOCK1 C4A C4B XKR6 TAFA4 F2RL1 LYST	7.36e-05	274	77	7	GO:0006909
GeneOntologyBiologicalProcess	detection of chemical stimulus	TAS2R13 TAS2R33 TAS2R36 C4B TAS2R31 TAS2R43 TAS2R20 TAS2R46 OR6B2	1.43e-04	524	77	9	GO:0009593
GeneOntologyBiologicalProcess	sensory perception	TAS2R13 TAS2R33 TAS2R36 SCARB2 NTSR2 KCNQ3 TAS2R31 TAS2R43 TAS2R20 TAFA4 TAS2R46 MYO15A OR6B2	1.55e-04	1072	77	13	GO:0007600
GeneOntologyBiologicalProcess	plasma membrane invagination	DOCK1 SNX33 XKR6 F2RL1	2.08e-04	78	77	4	GO:0099024
GeneOntologyBiologicalProcess	superoxide metabolic process	DUOX1 NOX5 TAFA4 F2RL1	2.64e-04	83	77	4	GO:0006801
GeneOntologyBiologicalProcess	membrane invagination	DOCK1 SNX33 XKR6 F2RL1	3.16e-04	87	77	4	GO:0010324
GeneOntologyBiologicalProcess	positive regulation of apoptotic cell clearance	C4A C4B	3.80e-04	8	77	2	GO:2000427
MousePheno	abnormal astrocyte morphology	FA2H SCARB2 LTN1 KCNQ3 EPG5 VEGFA	2.52e-05	155	53	6	MP:0002182
MousePheno	decreased tail pigmentation	TPCN2 HPS5 LYST	4.03e-05	18	53	3	MP:0011277
MousePheno	astrocytosis	SCARB2 LTN1 KCNQ3 EPG5 VEGFA	4.27e-05	103	53	5	MP:0003354
MousePheno	paresis	LTN1 LRRC8A LYST VEGFA	4.70e-05	53	53	4	MP:0000754
MousePheno	increased astrocyte number	SCARB2 LTN1 KCNQ3 EPG5 VEGFA	5.12e-05	107	53	5	MP:0012065
MousePheno	abnormal astrocyte number	SCARB2 LTN1 KCNQ3 EPG5 VEGFA	6.38e-05	112	53	5	MP:0012064
MousePheno	abnormal CNS glial cell morphology	FA2H SCARB2 LTN1 KCNQ3 LYST EPG5 VEGFA	7.01e-05	272	53	7	MP:0000952
MousePheno	paralysis	FA2H SCARB2 LTN1 EPG5 VEGFA	8.51e-05	119	53	5	MP:0000753
MousePheno	decreased eye pigmentation	TPCN2 HPS5 LYST	8.64e-05	23	53	3	MP:0005172
MousePheno	increased freezing behavior	FA2H LTN1 C4A C4B TMEM255A	1.20e-04	128	53	5	MP:0020421
MousePheno	delayed hair regrowth	FA2H LYST	1.40e-04	5	53	2	MP:0000423
MousePheno	paraparesis	LTN1 LRRC8A LYST	2.36e-04	32	53	3	MP:0009434
MousePheno	abnormal platelet ADP level	HPS5 LYST	2.93e-04	7	53	2	MP:0009556
MousePheno	decreased platelet ADP level	HPS5 LYST	2.93e-04	7	53	2	MP:0009557
MousePheno	abnormal glial cell morphology	FA2H SCARB2 LTN1 KCNQ3 LYST EPG5 VEGFA	3.05e-04	345	53	7	MP:0003634
MousePheno	hindlimb paresis	LTN1 LRRC8A LYST	3.65e-04	37	53	3	MP:0031204
MousePheno	abnormal freezing behavior	FA2H LTN1 C4A C4B TMEM255A	3.70e-04	163	53	5	MP:0020420
MousePheno	abnormal tail pigmentation	TPCN2 HPS5 LYST	4.27e-04	39	53	3	MP:0005174
MousePheno	gliosis	SCARB2 LTN1 KCNQ3 EPG5 VEGFA	4.61e-04	171	53	5	MP:0002183
MousePheno	decreased skeletal muscle fiber size	DOCK1 LTN1 EPG5 VEGFA	4.92e-04	97	53	4	MP:0009400
MousePheno	abnormal coat appearance	TPCN2 TRANK1 FA2H SEL1L3 LRRC8A SNX33 HPS5 LYST EPG5 VEGFA	5.69e-04	774	53	10	MP:0001510
MousePheno	abnormal platelet ATP level	HPS5 LYST	6.22e-04	10	53	2	MP:0009447
MousePheno	decreased platelet ATP level	HPS5 LYST	6.22e-04	10	53	2	MP:0009448
Domain	TAS2R	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	5.25e-08	26	74	5	PF05296
Domain	T2R	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	5.25e-08	26	74	5	IPR007960
Domain	-	SAMD4B SAMD4A	1.55e-05	2	74	2	1.25.40.170
Domain	PHAT_dom	SAMD4B SAMD4A	1.55e-05	2	74	2	IPR015327
Domain	RSN1_7TM	TMEM63C TMEM63A	4.63e-05	3	74	2	IPR003864
Domain	PHM7_cyt	TMEM63C TMEM63A	4.63e-05	3	74	2	IPR027815
Domain	PHM7_cyt	TMEM63C TMEM63A	4.63e-05	3	74	2	PF14703
Domain	RSN1_7TM	TMEM63C TMEM63A	4.63e-05	3	74	2	PF02714
Domain	Csc1_N	TMEM63C TMEM63A	4.63e-05	3	74	2	IPR032880
Domain	RSN1_TM	TMEM63C TMEM63A	4.63e-05	3	74	2	PF13967
Domain	Anaphylatoxin_comp_syst	C4A C4B	1.54e-04	5	74	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	1.54e-04	5	74	2	IPR001840
Domain	Cyt_B5_heme-BS	FA2H CYB5A	1.54e-04	5	74	2	IPR018506
Domain	ANATO	C4A C4B	3.21e-04	7	74	2	SM00104
Domain	ANATO	C4A C4B	3.21e-04	7	74	2	PF01821
Domain	NAD_binding_6	DUOX1 NOX5	3.21e-04	7	74	2	PF08030
Domain	FAD_binding_8	DUOX1 NOX5	3.21e-04	7	74	2	PF08022
Domain	ANAPHYLATOXIN_2	C4A C4B	3.21e-04	7	74	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	3.21e-04	7	74	2	PS01177
Domain	FAD-bd_8	DUOX1 NOX5	3.21e-04	7	74	2	IPR013112
Domain	Fe_red_NAD-bd_6	DUOX1 NOX5	3.21e-04	7	74	2	IPR013121
Domain	Anaphylatoxin/fibulin	C4A C4B	3.21e-04	7	74	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	4.27e-04	8	74	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	4.27e-04	8	74	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	4.27e-04	8	74	2	IPR019742
Domain	A2M_N	C4A C4B	6.83e-04	10	74	2	PF01835
Domain	A2M_N	C4A C4B	6.83e-04	10	74	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	6.83e-04	10	74	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	6.83e-04	10	74	2	PS00477
Domain	A2M	C4A C4B	6.83e-04	10	74	2	PF00207
Domain	A2M_N_2	C4A C4B	6.83e-04	10	74	2	IPR011625
Domain	A2M_comp	C4A C4B	6.83e-04	10	74	2	IPR011626
Domain	A2M_N_2	C4A C4B	6.83e-04	10	74	2	PF07703
Domain	A2M_recep	C4A C4B	6.83e-04	10	74	2	PF07677
Domain	A2M_comp	C4A C4B	6.83e-04	10	74	2	PF07678
Domain	Macroglobln_a2	C4A C4B	6.83e-04	10	74	2	IPR001599
Domain	Ferric_reduct	DUOX1 NOX5	9.96e-04	12	74	2	PF01794
Domain	Fe3_Rdtase_TM_dom	DUOX1 NOX5	9.96e-04	12	74	2	IPR013130
Domain	CYTOCHROME_B5_2	FA2H CYB5A	1.17e-03	13	74	2	PS50255
Domain	CYTOCHROME_B5_1	FA2H CYB5A	1.17e-03	13	74	2	PS00191
Domain	Cyt-b5	FA2H CYB5A	1.37e-03	14	74	2	PF00173
Domain	Cyt_B5-like_heme/steroid-bd	FA2H CYB5A	1.37e-03	14	74	2	IPR001199
Domain	Cyt-b5	FA2H CYB5A	1.37e-03	14	74	2	SM01117
Domain	-	FA2H CYB5A	1.37e-03	14	74	2	3.10.120.10
Domain	P-loop_NTPase	TRANK1 MDN1 MPP4 NDST2 SHPRH ABCC9 RASL10B MYO15A PARPBP DNAH7	1.82e-03	848	74	10	IPR027417
Domain	C345C	C4A C4B	2.03e-03	17	74	2	SM00643
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	2.27e-03	18	74	2	IPR008930
Domain	Fd_Rdtase_FAD-bd	DUOX1 NOX5	2.54e-03	19	74	2	IPR017927
Domain	NTR	C4A C4B	2.54e-03	19	74	2	PF01759
Domain	FAD_FR	DUOX1 NOX5	2.54e-03	19	74	2	PS51384
Domain	Netrin_module_non-TIMP	C4A C4B	2.54e-03	19	74	2	IPR018933
Domain	Riboflavin_synthase-like_b-brl	DUOX1 NOX5	2.54e-03	19	74	2	IPR017938
Domain	-	TRANK1 MDN1 MPP4 NDST2 SHPRH ABCC9 RASL10B MYO15A DNAH7	2.67e-03	746	74	9	3.40.50.300
Domain	NTR	C4A C4B	3.71e-03	23	74	2	PS50189
Domain	Netrin_domain	C4A C4B	3.71e-03	23	74	2	IPR001134
Domain	TIMP-like_OB-fold	C4A C4B	4.73e-03	26	74	2	IPR008993
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	5.27e-08	31	47	5	MM15691
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.33e-07	37	47	5	MM15067
Pathway	REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.75e-07	39	47	5	M793
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	4.57e-07	47	47	5	M42524
Pathway	KEGG_TASTE_TRANSDUCTION	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	7.65e-07	52	47	5	M5785
Pathway	WP_GPCRS_ODORANT	TAS2R13 MRGPRF TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.28e-05	157	47	6	MM15872
Pathway	REACTOME_GPCR_LIGAND_BINDING	TAS2R13 NTSR2 TAS2R31 TAS2R43 TAS2R20 TAS2R46 ADGRE2 F2RL1	7.77e-05	430	47	8	MM15160
Pathway	REACTOME_GPCR_LIGAND_BINDING	TAS2R13 NTSR2 TAS2R31 TAS2R43 TAS2R20 TAS2R46 ADGRE2 F2RL1	1.30e-04	463	47	8	M507
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	2.26e-04	7	47	2	MM14685
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	3.01e-04	8	47	2	M27031
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	3.01e-04	8	47	2	M47872
Pathway	REACTOME_SENSORY_PERCEPTION	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	4.09e-04	190	47	5	MM15687
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	5.87e-04	11	47	2	MM1430
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	5.87e-04	11	47	2	M47874
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	7.03e-04	12	47	2	MM1368
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	8.29e-04	13	47	2	M4732
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	1.11e-03	15	47	2	M7146
Pathway	REACTOME_SIGNALING_BY_GPCR	TAS2R13 NTSR2 TAS2R31 TAS2R43 TAS2R20 TAS2R46 ADGRE2 F2RL1	1.20e-03	646	47	8	MM14962
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C4A C4B	1.43e-03	17	47	2	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	1.43e-03	17	47	2	MM1369
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	1.99e-03	20	47	2	M917
Pathway	REACTOME_SIGNALING_BY_GPCR	TAS2R13 NTSR2 TAS2R31 TAS2R43 TAS2R20 TAS2R46 ADGRE2 F2RL1	2.04e-03	702	47	8	M746
Pathway	WP_COMPLEMENT_ACTIVATION	C4A C4B	2.41e-03	22	47	2	M39502
Pubmed	Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	7.67e-11	13	81	5	15938754
Pubmed	A novel family of mammalian taste receptors.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.19e-09	21	81	5	10761934
Pubmed	Evolutionary relationships of the Tas2r receptor gene families in mouse and human.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.54e-09	22	81	5	12734386
Pubmed	Receptors for bitter and sweet taste.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	3.10e-09	25	81	5	12139982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	3.83e-09	26	81	5	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	4.69e-09	27	81	5	12581520
Pubmed	Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	8.23e-09	30	81	5	17273929
Pubmed	Adaptive diversification of bitter taste receptor genes in Mammalian evolution.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	8.23e-09	30	81	5	12679530
Pubmed	The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.	TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.33e-08	12	81	4	12379855
Pubmed	Evolution of bitter taste receptors in humans and apes.	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.60e-08	34	81	5	15496549
Pubmed	Identification and characterization of human taste receptor genes belonging to the TAS2R family.	TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.92e-08	13	81	4	12584440
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R13 TAS2R31 TAS2R43 TAS2R46	2.34e-07	23	81	4	20022913
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R13 TAS2R43 TAS2R20 TAS2R46	5.36e-07	28	81	4	15744053
Pubmed	Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle.	NDST2 C4A C4B	1.01e-06	9	81	3	15905575
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	5.36e-06	2	81	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	5.36e-06	2	81	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	5.36e-06	2	81	2	15998580
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	5.36e-06	2	81	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	5.36e-06	2	81	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	5.36e-06	2	81	2	3696167
Pubmed	Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin.	TAS2R31 TAS2R43	5.36e-06	2	81	2	17702579
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	5.36e-06	2	81	2	1357031
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	5.36e-06	2	81	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	5.36e-06	2	81	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	5.36e-06	2	81	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	5.36e-06	2	81	2	17645767
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	5.36e-06	2	81	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	5.36e-06	2	81	2	12207352
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	5.36e-06	2	81	2	30026462
Pubmed	Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways.	F2RL1 VEGFA	5.36e-06	2	81	2	16650817
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	5.36e-06	2	81	2	6559257
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	5.36e-06	2	81	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	5.36e-06	2	81	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	5.36e-06	2	81	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	5.36e-06	2	81	2	20506482
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	5.36e-06	2	81	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	5.36e-06	2	81	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	5.36e-06	2	81	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	5.36e-06	2	81	2	23918728
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	5.36e-06	2	81	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	5.36e-06	2	81	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	5.36e-06	2	81	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	5.36e-06	2	81	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	5.36e-06	2	81	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	5.36e-06	2	81	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	5.36e-06	2	81	2	2997024
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	5.36e-06	2	81	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	5.36e-06	2	81	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	5.36e-06	2	81	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	5.36e-06	2	81	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	5.36e-06	2	81	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	5.36e-06	2	81	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	5.36e-06	2	81	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	5.36e-06	2	81	2	21345967
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	5.36e-06	2	81	2	5919331
Pubmed	Mammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granules.	SAMD4B SAMD4A	5.36e-06	2	81	2	16221671
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	5.36e-06	2	81	2	3167981
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	5.36e-06	2	81	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	5.36e-06	2	81	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	5.36e-06	2	81	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	5.36e-06	2	81	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	5.36e-06	2	81	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	5.36e-06	2	81	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	5.36e-06	2	81	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	5.36e-06	2	81	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	5.36e-06	2	81	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	5.36e-06	2	81	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	5.36e-06	2	81	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	5.36e-06	2	81	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	5.36e-06	2	81	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	5.36e-06	2	81	2	17728371
Pubmed	Bitter taste receptors for saccharin and acesulfame K.	TAS2R31 TAS2R43	5.36e-06	2	81	2	15537898
Pubmed	Structure and organization of the C4 genes.	C4A C4B	5.36e-06	2	81	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	5.36e-06	2	81	2	6149581
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	5.36e-06	2	81	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	5.36e-06	2	81	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	5.36e-06	2	81	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	5.36e-06	2	81	2	8132550
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	5.36e-06	2	81	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	5.36e-06	2	81	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	5.36e-06	2	81	2	6192448
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	5.36e-06	2	81	2	6167582
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	5.36e-06	2	81	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	5.36e-06	2	81	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	5.36e-06	2	81	2	7365238
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	5.36e-06	2	81	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	5.36e-06	2	81	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	5.36e-06	2	81	2	17506029
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	5.36e-06	2	81	2	17971360
Pubmed	Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.	C4A C4B	5.36e-06	2	81	2	23715124
Pubmed	Identification of the 5'-flanking regulatory region responsible for the difference in transcriptional control between mouse complement C4 and Slp genes.	C4A C4B	5.36e-06	2	81	2	3464002
Pubmed	Complete nucleotide and derived amino acid sequences of the fourth component of mouse complement (C4). Evolutionary aspects.	C4A C4B	5.36e-06	2	81	2	2993295
Pubmed	Clinical features of patients with homozygous complement C4A or C4B deficiency.	C4A C4B	5.36e-06	2	81	2	29928053
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	5.36e-06	2	81	2	17971229
Pubmed	Genetic deficiency of C4 presenting with recurrent infections and a SLE-like disease. Genetic and immunologic studies.	C4A C4B	5.36e-06	2	81	2	6881182
Pubmed	Identification of the site of sulfation of the fourth component of human complement.	C4A C4B	5.36e-06	2	81	2	3944109
Pubmed	Partial C4 deficiency in juvenile idiopathic arthritis patients.	C4A C4B	5.36e-06	2	81	2	17921792
Pubmed	Complement activation and complement receptors on follicular dendritic cells are critical for the function of a targeted adjuvant.	C4A C4B	5.36e-06	2	81	2	21880985
Pubmed	Amino acid sequence around the thiol and reactive acyl groups of human complement component C4.	C4A C4B	5.36e-06	2	81	2	6978711
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	5.36e-06	2	81	2	35898513
Cytoband	12p13.2	TAS2R31 TAS2R43 TAS2R20 TAS2R46	1.15e-06	45	79	4	12p13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr12p13	TAS2R13 TAS2R31 TAS2R43 TAS2R20 TAS2R46 LRRC23	3.43e-05	353	79	6	chr12p13
Cytoband	11q13.3	TPCN2 MRGPRF	6.60e-04	22	79	2	11q13.3
GeneFamily	Taste 2 receptors	TAS2R13 TAS2R33 TAS2R36 TAS2R31 TAS2R43 TAS2R20 TAS2R46	2.02e-11	39	54	7	1162
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	3.11e-04	9	54	2	1234
GeneFamily	Solute carriers	SLC9A4 SLC35F3 SLC5A12 SLC35F1 SLC2A12 SLC4A11	1.12e-03	395	54	6	752
GeneFamily	Complement system\|Sushi domain containing	C4A C4B	5.17e-03	36	54	2	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	5.45e-03	37	54	2	454
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_200	DOCK1 SEL1L3 SLC35F1 PARPBP F2RL1 PRPF39	1.59e-05	160	71	6	gudmap_developingKidney_e15.5_ureter tip_200_flank cortic collct
CoexpressionAtlas	DevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#3_top-relative-expression-ranked_500	DOCK1 SHPRH PARPBP PRPF39 VEGFA	4.54e-05	117	71	5	gudmap_developingKidney_e15.5_Medullary collecting duct_500_k3
CoexpressionAtlas	DevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_top-relative-expression-ranked_500	DOCK1 SEL1L3 SHPRH SLC35F1 PARPBP F2RL1 PRPF39 VEGFA	6.20e-05	406	71	8	gudmap_developingKidney_e15.5_ureter tip_500_flank cortic collct
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9A4 IQCH TMC5 DNAH7 LRRC23	8.35e-06	155	79	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9A4 IQCH TMC5 DNAH7 LRRC23	8.35e-06	155	79	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SND1-IT1 ADGRE2 TRIM59 LRRC23 VEGFA	1.50e-05	175	79	5	334fad1a147de6c007cec5089c02c35cf3220f1b
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_A2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SND1-IT1 ADGRE2 TRIM59 LRRC23 VEGFA	1.50e-05	175	79	5	da191dfb8a7f976a632a3a0b923942ab54f5c8c1
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H OR6B2 TRIM59 TMEM63A	1.59e-05	177	79	5	80aee5154f21810be0645d003b06568d4dcecc36
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FA2H LRRC8A SLC5A12 F2RL1 SLC4A11	1.63e-05	178	79	5	9a3ef66814dfca7b37024e7f79e86ea8c72ae10f
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MRGPRF LRTM1 ABCC9 SLC5A12 SLC35F1	1.63e-05	178	79	5	066dbc4cc2083c549d98122ed44707127f34d582
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FA2H LRRC8A SLC5A12 F2RL1 SLC4A11	1.63e-05	178	79	5	b413a634283550fa224db7d0d05956e3f64694a1
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FA2H LRRC8A SLC5A12 F2RL1 SLC4A11	1.63e-05	178	79	5	49a2271718637522f74334068d252963ee13b1ce
ToppCell	BAL-Severe-Epithelial-Epithelial-undefined_Epi\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FA2H LRRC8A SLC5A12 F2RL1 SLC4A11	1.63e-05	178	79	5	19b5432aa1d7f616d58a106543c18cf2d7ca840c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC35F3 TMC5 SLC2A12 DNAH7 LRRC23	2.17e-05	189	79	5	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	Severe_COVID-19-Epithelial-undefined_Epi\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	FA2H LRRC8A TMC5 F2RL1 SLC4A11	2.17e-05	189	79	5	8cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	SEL1L3 KCNQ3 MTCL1 SLC5A12 SAMD4A	2.17e-05	189	79	5	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	URB1 MDN1 ABCC9 SLC35F1 SAMD4A	2.23e-05	190	79	5	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	URB1 MDN1 ABCC9 SLC35F1 SAMD4A	2.23e-05	190	79	5	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK1 AHI1-DT SEL1L3 DNAH7 SLC4A11	2.29e-05	191	79	5	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC35F3 SEL1L3 KCNQ3 MTCL1 SAMD4A	2.29e-05	191	79	5	1cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell	AT2\|World / shred by cell class for parenchyma	DUOX1 ERG28 SNX33 TMC5 CYB5A	2.46e-05	194	79	5	e773f5ef3abce7113a6b7cc7cbe68de873d4a17f
ToppCell	(7)_Epithelial-B_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	DUOX1 ERG28 SNX33 TMC5 CYB5A	2.59e-05	196	79	5	345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCell	AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	DUOX1 ERG28 SNX33 TMC5 CYB5A	2.72e-05	198	79	5	92c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DUOX1 KCNQ3 ABCC9 TMC5 CYB5A	2.72e-05	198	79	5	f948391296c261c473d339069a6d0f20ccd6f38f
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IQCH SEL1L3 TMC5 DNAH7 LRRC23	2.78e-05	199	79	5	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC9A4 IQCH TMC5 DNAH7 LRRC23	2.78e-05	199	79	5	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IQCH SEL1L3 TMC5 DNAH7 LRRC23	2.78e-05	199	79	5	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SLC9A4 IQCH TMC5 DNAH7 LRRC23	2.85e-05	200	79	5	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SLC9A4 IQCH TMC5 DNAH7 LRRC23	2.85e-05	200	79	5	4992dbf0514d674017315dbd20d91dfec0c608e9
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	DUOX1 TMC5 DNAH7 CYB5A LRRC23	2.85e-05	200	79	5	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(red_nucleus,_magnocellular/parvicellular_(RMC/RPC))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC9A4 TSPO2 DCSTAMP	7.01e-05	45	79	3	a5d7f4dacfdbecf7d82b2bc75fc3668b9a208abb
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(red_nucleus,_magnocellular/parvicellular_(RMC/RPC))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC9A4 TSPO2 DCSTAMP	7.01e-05	45	79	3	4e9fd1e4fecb51298f66ca5e1ec87a2a7d314724
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(red_nucleus,_magnocellular/parvicellular_(RMC/RPC))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SLC9A4 TSPO2 DCSTAMP	7.01e-05	45	79	3	34020aa7499e57d7560d7f5cf91c3bd1e69ce481
ToppCell	primary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-Oligo_Serpinb1a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FA2H SNX33 TRIM59 TMEM63A	1.10e-04	139	79	4	789edd3c98e7c5c1cc402c780fded9a9dfd1dfb8
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte-Oligo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FA2H SNX33 TRIM59 TMEM63A	1.47e-04	150	79	4	b30f52b94ce772632a1f2f5e0837db876cf92651
ToppCell	frontal_cortex-Non-neuronal-oligodendrocyte\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	FA2H SNX33 TRIM59 TMEM63A	1.47e-04	150	79	4	05b9a9cbc5a95cdaf45d5f173e132acd4da9aa8a
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	LRTM1 TAFA4 PARPBP	1.58e-04	59	79	3	b2c10c4c0a750d7f49f5a813ab5d103fb07ca76b
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	LRTM1 TAFA4 PARPBP	1.58e-04	59	79	3	bcac768e1e034e27bab7cad3c2bf09a8f0a819ad
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	LRTM1 TAFA4 PARPBP	1.58e-04	59	79	3	f9b9464f4d786991aad01b47e2a8fd33f889c2e2
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9A4 IQCH TMC5 DNAH7	1.62e-04	154	79	4	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLC9A4 IQCH TMC5 DNAH7	1.62e-04	154	79	4	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MRGPRF SLC5A12 SLC2A12 VEGFA	1.84e-04	159	79	4	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MRGPRF SLC5A12 SLC2A12 VEGFA	1.84e-04	159	79	4	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MRGPRF SLC5A12 SLC2A12 VEGFA	1.84e-04	159	79	4	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	droplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 DCSTAMP MYO15A HPS5	1.97e-04	162	79	4	8a488ecd25ef41468c3c7766eb936dbc2f7665a9
ToppCell	droplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 CYP8B1 DCSTAMP MYO15A	2.07e-04	164	79	4	a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCell	droplet-Fat-Gat-18m-Hematologic\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 TSPO2 PARPBP TRIM59	2.07e-04	164	79	4	7dbe34a98a3b475c1ba678db8a5494c0c6a91e2d
ToppCell	droplet-Fat-Gat-18m-Hematologic-erythroblast\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 TSPO2 PARPBP TRIM59	2.07e-04	164	79	4	febcb8f8b305aa94e21131fa83d2890f7a6838fc
ToppCell	droplet-Fat-Gat-18m-Hematologic-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRANK1 TSPO2 PARPBP TRIM59	2.12e-04	165	79	4	1e89154114327650df39befb2c56d0379ea6a221
ToppCell	facs-Lung-nan-3m-Epithelial-type_I_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTCL1 F2RL1 SLC2A12 SAMD4A	2.16e-04	166	79	4	11b0ae82b3068ef91715dbdd49fe8e9791b4a480
ToppCell	LPS-antiTNF-Epithelial_airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SEL1L3 ADAM2 TMC5 LRRC23	2.16e-04	166	79	4	eb942ed68677e55c46cb039046f45686d4062d7c
ToppCell	facs-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MTCL1 F2RL1 SLC2A12 SAMD4A	2.16e-04	166	79	4	fcc1aec31ebd39432d4cb284dc8fadf34e3c566a
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEL1L3 FADS6 TMC5 CYB5A	2.42e-04	171	79	4	fd59ac4a39748840b2ee1c930ea475433ff61485
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEL1L3 FADS6 TMC5 CYB5A	2.42e-04	171	79	4	d5960b40ad5b87aaa00c93a6b31cdf41cc4f1375
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-epithelial_cell_of_lung\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEL1L3 FADS6 TMC5 CYB5A	2.42e-04	171	79	4	d382430e5cdd0f2aac4fc093d8fe8d66efb4629b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEL1L3 FADS6 TMC5 CYB5A	2.42e-04	171	79	4	4347e6f62c04ea43299893ad4b79719049009a56
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ERG28 CENPL PARPBP TRIM59	2.48e-04	172	79	4	ba36581ae339191a12a6d3ead39eaf69d78be10e
ToppCell	Frontal_cortex-Macroglia\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ERG28 FA2H SNX33 TRIM59	2.53e-04	173	79	4	ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1-Inhibitory_Gad1Gad2_Htr3a.Phlda1_(Interneuron,__(candidate_CGE-derived_3))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IQCH RTL1 TMC5	2.62e-04	70	79	3	0f1dba07a2cd974a25239ae1728cfb007a37954c
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IQCH RTL1 TMC5	2.62e-04	70	79	3	c579fd093d30a5ee56f7cf1039120d00a6369649
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Phlda1-Inhibitory_Gad1Gad2_Htr3a.Phlda1_(Interneuron,__(candidate_CGE-derived_3))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IQCH RTL1 TMC5	2.62e-04	70	79	3	511ca39208a8a0efd24cca47270083d5024e6972
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC35F3 SEL1L3 DNAH7 SLC4A11	2.65e-04	175	79	4	284fdc7a9d303636a637041846850d19d114861a
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 ABCC9 SNX33 LRRC23	2.76e-04	177	79	4	7c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	URB1 TMC5 SLC4A11 CYB5A	2.76e-04	177	79	4	779ba86f53650772755b52460be03f18bb204e55
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	URB1 TMC5 SLC4A11 CYB5A	2.76e-04	177	79	4	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	facs-Heart-RV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MDN1 ABCC9 SNX33 LRRC23	2.76e-04	177	79	4	e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	DUOX1 KCNQ3 TMC5 VEGFA	2.88e-04	179	79	4	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NOX5 TMC5 DNAH7 LRRC23	2.88e-04	179	79	4	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	Control-Epithelial_cells-AT2\|Control / group, cell type (main and fine annotations)	DUOX1 KCNQ3 ABCC9 CYB5A	2.95e-04	180	79	4	198b19e7910b4a8cc7e820c525ab357c7f99f578
ToppCell	Thalamus-Macroglia\|Thalamus / BrainAtlas - Mouse McCarroll V32	FA2H SCARB2 SNX33 TRIM59	3.01e-04	181	79	4	4f62b63854a4e9fea6e839f0340e78392c66fb0e
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype\|TCGA-Lung / Sample_Type by Project: Shred V9	KCNQ3 TMC5 GGCX TMEM63A	3.01e-04	181	79	4	c783c2ecca7ab8e07646fa92dc7d436d24939d03
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.07e-04	182	79	4	d524ad5cf00f05ee27c9db2ffa2d4e30a1e2e21a
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.14e-04	183	79	4	5472cdce6d99314d229418412acf1fff6340db7d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DUOX1 KCNQ3 ABCC9 CYB5A	3.14e-04	183	79	4	6847c1252d6bb105524f812658112517fd351eab
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FA2H C4B TRIM59 TMEM63A	3.14e-04	183	79	4	eb1f1dd12d1e4f1a7029b5396baada23f7c971ff
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	DUOX1 KCNQ3 TMC5 VEGFA	3.14e-04	183	79	4	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.14e-04	183	79	4	93213124e55d1b673dd345188caf8b5bd31d99fe
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.20e-04	184	79	4	f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCell	COVID-19-Epithelial_cells-AT2\|COVID-19 / group, cell type (main and fine annotations)	DUOX1 KCNQ3 TMC5 CYB5A	3.20e-04	184	79	4	369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.20e-04	184	79	4	5939527d24d299e562e707469c9123890edd76be
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.20e-04	184	79	4	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AHI1-DT SEL1L3 DNAH7 SLC4A11	3.20e-04	184	79	4	da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCell	droplet-Heart-HEART-1m-Hematologic-erythrocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPO2 TRIM59 PEX26	3.21e-04	75	79	3	f1ad409d1b2c5f23bf2b22137e612d627c041b97
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.27e-04	185	79	4	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	KCNQ3 TMC5 SAMD4A VEGFA	3.27e-04	185	79	4	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	DUOX1 KCNQ3 TMC5 CYB5A	3.27e-04	185	79	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.27e-04	185	79	4	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.27e-04	185	79	4	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SEL1L3 XKR6 TMC5 CYB5A	3.34e-04	186	79	4	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.34e-04	186	79	4	d57c40b3fe5cfc87e771df76533d9a3e94678b04
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.34e-04	186	79	4	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC35F3 SEL1L3 KCNQ3 SAMD4A	3.34e-04	186	79	4	f28d72b47624b69a580b4429e2be560a26898591
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.34e-04	186	79	4	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.40e-04	187	79	4	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRGPRF TMEM63C ABCC9 SAMD4A	3.40e-04	187	79	4	218c9b4f28499389c43005d9626af2ac01066027
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC8A SNX33 SLC2A12 SLC4A11	3.40e-04	187	79	4	6e5c38425b6b1d4774f8dcea7e146f1eab785c3e
ToppCell	saliva-Mild-Moderate_progression_d12-25-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LRRC8A SNX33 SLC2A12 SLC4A11	3.40e-04	187	79	4	43ef900b76f3c38bd8ce9858201124130c743d56
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.40e-04	187	79	4	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	SEL1L3 KCNQ3 SLC5A12 CYB5A	3.40e-04	187	79	4	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.40e-04	187	79	4	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	droplet-Lung-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MRGPRF TMEM63C ABCC9 SAMD4A	3.40e-04	187	79	4	c7ac4b328efc2ebb72f71154661914193ff402ca
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.47e-04	188	79	4	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FA2H TRIM59 TMEM63A	3.47e-04	188	79	4	60242c29c7f16c94a84685d3bc4ed93a66e70152
Disease	Graves' disease (is_implicated_in)	C4A C4B VEGFA	1.20e-04	39	72	3	DOID:12361 (is_implicated_in)
Disease	platelet storage pool deficiency (implicated_via_orthology)	HPS5 LYST	6.04e-04	15	72	2	DOID:2223 (implicated_via_orthology)
Disease	Antibody Deficiency Syndrome	C4A EPG5	7.80e-04	17	72	2	C0003257
Disease	theta wave measurement	TMC5 CYB5A	7.80e-04	17	72	2	EFO_0006873
Disease	brain infarction	SLC35F3 SNX33	8.76e-04	18	72	2	EFO_0004277
Disease	DiGeorge syndrome (implicated_via_orthology)	DOCK1 VEGFA	9.77e-04	19	72	2	DOID:11198 (implicated_via_orthology)
Disease	serum alanine aminotransferase measurement	TPCN2 TRANK1 CYP8B1 SAMD4B LTN1 XKR6 TRIM59 VEGFA	1.24e-03	869	72	8	EFO_0004735
Disease	QRS duration, response to sulfonylurea	MDN1 TAFA4	1.44e-03	23	72	2	EFO_0005055, EFO_0007922
Disease	Immunologic Deficiency Syndromes	C4A EPG5	1.44e-03	23	72	2	C0021051

Protein segments in the cluster

Peptide	Gene	Start	Entry
LHKELVRLFNVYILW	EPG5	1396	Q9HCE0
WIETTAYALLHLLLH	C4B	1261	P0C0L5
LHYLYLATLTWMLLE	ADGRE2	606	Q9UHX3
LLHTFLRWKTSYLVL	ADAM2	246	Q99965
HTKLYFLQWLSVFLD	GVINP1	1341	Q7Z2Y8
KLLKHSVIVAIDYWL	ABCC9	1001	O60706
WLSKALYHVTFLLRI	AHI1-DT	256	P0C7V0
YLEHILGFQKTLLLW	FAM200A	371	Q8TCP9
VIAIAWLLYCHKTRL	IQCH	401	Q86VS3
NIFLFYVKLRWLLKH	MTCL1	1036	Q9Y4B5
SDVLLTWKYLLHEKL	PARPBP	61	Q9NWS1
KWLSLASLLVYVAAF	SLC2A12	461	Q8TD20
THLSYLLVWLLLIFH	NOX5	401	Q96PH1
WIYSLKTLEELHLTG	LRRC8A	511	Q8IWT6
GYLLTWKLILTFFKA	LTN1	1476	O94822
FWLTHHLYILLYVLL	DUOX1	1221	Q9NRD9
KRHLTWTLKLLQFLY	KIAA0100	296	Q14667
CHLLGLKLWLEKFVY	LRTM1	186	Q9HBL6
EVVLRAWSHFLLTYK	MDN1	2141	Q9NU22
AKVLFTALYALIWAL	NTSR2	31	O95665
AKVLYALLFSWLITR	MYO15A	1556	Q9UKN7
WALLYHALVFLIVLG	KCNQ3	121	O43525
LLSWGYSQLILHLIK	HPS5	951	Q9UPZ3
ESKLLWLHSLLSFFY	TMEM63C	181	Q9P1W3
LSPLNYLTHLLWLKA	LRRC23	106	Q53EV4
SLHFLYKLAQLFRWI	PEX26	276	Q7Z412
SLYLTKIHFWLPVLK	DCSTAMP	441	Q9H295
IHNKTLYHITLWTFL	ERG28	71	Q9UKR5
LYHITLWTFLLALGH	ERG28	76	Q9UKR5
TWLILHHKVYDLTKF	CYB5A	26	P00167
LLHSPWLQALLKIYD	MPP4	56	Q96JB8
DLLWLHTIFAVIYLF	TMEM63A	191	O94886
LSVDLWIHYINFLKE	PRPF39	161	Q86UA1
DLLSVIWFPLKIAYH	F2RL1	121	P55085
LGTFLWSLIEYLIHR	FA2H	221	Q7L5A8
AAYTLLLHAKLLKWS	DOCK1	1236	Q14185
FLLHKQWTLYSLTPL	CENPL	66	Q8N0S6
IFSRILTWHLEICYK	DNAH7	2126	Q8WXX0
IFLPSKWQHLVLTYL	LYST	1586	Q99698
WIETTAYALLHLLLH	C4A	1261	P0C0L4
SFWALLYLLKHPEAI	CYP8B1	291	Q9UNU6
ALISLGLYSHYWLLL	FADS6	201	Q8N9I5
ILVFPLLATILSYWH	OR6B2	206	Q6IFH4
LLATILSYWHITLAV	OR6B2	211	Q6IFH4
DELHFLLSHLYIWLA	MROH5	581	Q6ZUA9
CLLSYSLLFWKVHHL	SND1-IT1	51	Q9HBX3
ILHFFRGLLYWKNTL	RTL1	1076	A6NKG5
KYNWHILLLFSELLK	RASL10B	161	Q96S79
EILVSWFLALHYLAI	TAS2R13	61	Q9NYV9
IWLATSLSIFYLLKI	TAS2R20	96	P59543
NWLATSLSIFYLLKI	TAS2R31	96	P59538
IWLAASLSIFYLLKI	TAS2R33	96	P0DSN6
IWLATSLSIFYLLKI	TAS2R36	96	P0DTE0
NWLATTLSIFYLLKI	TAS2R43	96	P59537
NWLATSLSIFYLLKI	TAS2R46	96	P59540
KSVLLSHWLFLAYVL	TAFA4	11	Q96LR4
KGTAYHWDLLLLAII	SLC4A11	676	Q8NBS3
RLLWGAILHSALIYF	SEL1L3	1051	Q68CR1
IHLYHLLWSATILNI	TMEM255A	216	Q5JRV8
LLWVLSLLVTCLHNY	MRGPRF	166	Q96AM1
WILLASLAKIGFHLY	SLC9A4	76	Q6AI14
DWLYNRLLHKFTVIS	SNX33	271	Q8WV41
HLYSFIAKILWRSAK	SHPRH	891	Q149N8
LLWGYKDEILSLIHV	SCARB2	176	Q14108
DYSLLTWILHILESK	URB1	1851	O60287
WTLTNYLYLHAIKKI	SLC35F3	161	Q8IY50
LLSWFFLLIRYKAVH	SLC35F1	171	Q5T1Q4
LLYSKSTSLTFHWKL	SENP3	136	Q9H4L4
LAWVLASYHKLLRDS	XKR6	331	Q5GH73
YLSRHWLFSPFKLLL	GGCX	231	P38435
SWLKSLRLHKYAALF	SAMD4B	306	Q5PRF9
LEFYLLWTHKLLMLH	PWP2	816	Q15269
SAIFKWLLLYSLPAL	UNQ5815/PRO19632	16	Q6UWF5
FWLHKLIFVDAVAYL	NDST2	286	P52849
LLLYGLVVSTALIWH	TSPO2	111	Q5TGU0
LPLFIHSIYSWIDTL	TMC5	871	Q6UXY8
ILCLPKSYIALLHYW	TRANK1	2431	O15050
SLALLLYLHHAKWSQ	VEGFA	11	P15692
LRYHLFIWSVFSPKL	PIGG	941	Q5H8A4
HAKLALYFNLLGLWI	SLC5A12	271	Q1EHB4
WLKSLRLHKYAALFS	SAMD4A	331	Q9UPU9
LLSNWLVKYEHKLTL	TEX46	36	H3BTG2
HFQKNLWLLGYLVVL	TPCN2	151	Q8NHX9
LCHIFYLLKEFVWKI	TRIM59	386	Q8IWR1
YIHLLLSLFLFLWFI	TMEM272	106	A0A1B0GTI8