Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	olfactory receptor activity	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	2.36e-17	431	91	22	GO:0004984
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR10A3 XCR1 OR5B3 OR2AK2 CELSR1 NPY1R OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 GPR153 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 TAS2R19 OR4D5 OR5AR1 OR2AG1 OR10D4P	1.27e-16	884	91	28	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR10A3 XCR1 OR5B3 OR2AK2 CELSR1 NPY1R OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 EBI3 OR6K2 OR5L1 GPR153 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 MERTK TAS2R19 OR4D5 OR5AR1 CD160 OR2AG1 OR10D4P	1.54e-14	1353	91	31	GO:0004888
GeneOntologyMolecularFunction	gap junction channel activity	GJA9 GJA5 GJA8 GJA10	4.74e-06	25	91	4	GO:0005243
GeneOntologyMolecularFunction	wide pore channel activity	GJA9 GJA5 GJA8 GJA10	2.38e-05	37	91	4	GO:0022829
GeneOntologyMolecularFunction	odorant binding	OR5B3 OR6K2 OR5L1 OR10K1 OR10J4 OR5AR1	2.52e-05	127	91	6	GO:0005549
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 SCARB1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 TAS2R19 OR4D5 OR5AR1 NOD2 OR2AG1 OR10D4P	1.60e-20	524	91	26	GO:0009593
GeneOntologyBiologicalProcess	detection of stimulus	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 SCARB1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 GJA10 OR2Z1 TAS2R19 OR4D5 NMT1 OR5AR1 NOD2 OR2AG1 OR10D4P	2.87e-19	722	91	28	GO:0051606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 TAS2R19 OR4D5 OR5AR1 OR2AG1 OR10D4P	6.47e-19	485	91	24	GO:0050907
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 GJA10 OR2Z1 TAS2R19 OR4D5 OR5AR1 OR2AG1 OR10D4P	3.10e-18	582	91	25	GO:0050906
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 TAS2R19 OR4D5 OR5AR1 OR2AG1 OR10D4P	1.02e-17	547	91	24	GO:0007606
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	1.27e-17	432	91	22	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	5.98e-17	465	91	22	GO:0007608
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR10A3 XCR1 OR5B3 OR2AK2 CELSR1 NPY1R OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 GPR153 OR13F1 ENTPD1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 TAS2R19 OR4D5 NMT1 OR5AR1 NOS2 ADCY5 OR2AG1 OR10D4P	1.95e-15	1395	91	32	GO:0007186
GeneOntologyBiologicalProcess	sensory perception	OR10A3 OR5B3 OR2AK2 NPY1R OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 GJA10 OR2Z1 TAS2R19 OR4D5 OR5AR1 OR2AG1 OR10D4P	4.78e-13	1072	91	26	GO:0007600
GeneOntologyCellularComponent	connexin complex	GJA9 GJA5 GJA8 GJA10	2.12e-06	22	89	4	GO:0005922
GeneOntologyCellularComponent	gap junction	GJA9 GJA5 GJA8 GJA10	1.82e-05	37	89	4	GO:0005921
HumanPheno	Long lower eyelashes	GJA5 GJA8	2.13e-05	2	24	2	HP:0040053
Domain	Olfact_rcpt	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1	1.49e-15	393	88	20	IPR000725
Domain	GPCR_Rhodpsn_7TM	OR10A3 XCR1 OR5B3 OR2AK2 NPY1R OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 GPR153 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1	3.85e-14	670	88	23	IPR017452
Domain	7tm_1	OR10A3 XCR1 OR5B3 OR2AK2 NPY1R OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 GPR153 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1	4.79e-14	677	88	23	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR10A3 XCR1 OR5B3 OR2AK2 NPY1R OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 GPR153 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1	6.13e-14	685	88	23	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR10A3 XCR1 OR5B3 OR2AK2 NPY1R OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 GPR153 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1	7.37e-14	691	88	23	PS50262
Domain	GPCR_Rhodpsn	OR10A3 XCR1 OR5B3 OR2AK2 NPY1R OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 GPR153 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1	7.59e-14	692	88	23	IPR000276
Domain	CONNEXINS_1	GJA9 GJA5 GJA8 GJA10	1.69e-06	19	88	4	PS00407
Domain	CONNEXINS_2	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	PS00408
Domain	Connexin	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	IPR000500
Domain	Connexin_CCC	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	IPR019570
Domain	Connexin_N	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	IPR013092
Domain	Connexin	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	PF00029
Domain	Connexin_CCC	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	SM01089
Domain	Connexin_CS	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	IPR017990
Domain	CNX	GJA9 GJA5 GJA8 GJA10	2.10e-06	20	88	4	SM00037
Domain	AAA+_ATPase	ABCC1 MCM9 ABCG5 DNAH11	4.79e-03	144	88	4	IPR003593
Domain	AAA	ABCC1 MCM9 ABCG5 DNAH11	4.79e-03	144	88	4	SM00382
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 OR4D5 OR5AR1 OR2AG1	1.25e-15	417	73	21	M4072
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1	4.55e-15	389	73	20	M14091
Pathway	REACTOME_SENSORY_PERCEPTION	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 TAS2R5 OR2M2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR10J4 OR2Z1 OR4D5 NMT1 OR5AR1 OR2AG1	5.15e-14	636	73	23	M41834
Pathway	REACTOME_GAP_JUNCTION_ASSEMBLY	GJA9 GJA5 GJA8 GJA10	4.28e-05	38	73	4	M14981
Pathway	REACTOME_GAP_JUNCTION_TRAFFICKING_AND_REGULATION	GJA9 GJA5 GJA8 GJA10	1.38e-04	51	73	4	M26972
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	3.77e-20	340	91	19	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	3.77e-20	340	91	19	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	4.45e-20	343	91	19	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR2M2 OR11A1 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	5.24e-20	346	91	19	14611657
Pubmed	The human olfactory receptor gene family.	OR10A3 OR5B3 OR2AK2 OR2M7 OR4K2 OR11A1 OR4K13 OR6K2 OR5L1 OR13F1 OR4K1 OR10AD1 OR10K1 OR2B3 OR2M5 OR2Z1 OR4D5 OR5AR1 OR2AG1 OR10D4P	1.14e-17	541	91	20	14983052
Pubmed	High-throughput microarray detection of olfactory receptor gene expression in the mouse.	OR2M7 OR2M2 OR2M5	6.92e-08	4	91	3	15377787
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR10A3 OR2M2 OR4K1 OR10AD1 OR2B3 OR10J4 OR2Z1 OR2AG1	1.18e-07	219	91	8	12213199
Pubmed	Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics.	ABCC1 HNF1A CYP3A4	3.75e-06	12	91	3	19349540
Pubmed	Influence of sex and diet on quantitative trait loci for HDL cholesterol levels in an SM/J by NZB/BlNJ intercross population.	HNF1A SCARB1 ABCG5	3.75e-06	12	91	3	14993241
Pubmed	Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions.	GJA8 GJA10	6.77e-06	2	91	2	25823610
Pubmed	1q21.1 Recurrent Deletion	GJA5 GJA8	6.77e-06	2	91	2	21348049
Pubmed	Nod2 Deficiency in mice is Associated with Microbiota Variation Favouring the Expansion of mucosal CD4+ LAP+ Regulatory Cells.	NOS2 NOD2	6.77e-06	2	91	2	30250234
Pubmed	Enhancement of CYP3A4 activity in Hep G2 cells by lentiviral transfection of hepatocyte nuclear factor-1 alpha.	HNF1A CYP3A4	6.77e-06	2	91	2	24733486
Pubmed	Synergistic gene interactions control the induction of the mitochondrial uncoupling protein (Ucp1) gene in white fat tissue.	GJA5 GJA8 NPY1R	1.15e-05	17	91	3	10931824
Pubmed	An expression atlas of connexin genes in the mouse.	GJA5 GJA8 GJA10	1.37e-05	18	91	3	15081111
Pubmed	The novel mouse connexin39 gene is expressed in developing striated muscle fibers.	GJA5 GJA8 GJA10	1.37e-05	18	91	3	15466892
Pubmed	An update on connexin genes and their nomenclature in mouse and man.	GJA5 GJA8 GJA10	1.63e-05	19	91	3	14681012
Pubmed	Scavenger receptor BI and ABCG5/G8 differentially impact biliary sterol secretion and reverse cholesterol transport in mice.	SCARB1 ABCG5	2.03e-05	3	91	2	23401258
Pubmed	Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.	SCARB1 ABCG5	2.03e-05	3	91	2	19637290
Pubmed	Thrombin induces inducible nitric oxide synthase expression via the MAPK, MSK1, and NF-κB signaling pathways in alveolar macrophages.	RPS6KA5 NOS2	2.03e-05	3	91	2	22004609
Pubmed	Role for NOD2 in Mycobacterium tuberculosis-induced iNOS expression and NO production in human macrophages.	NOS2 NOD2	2.03e-05	3	91	2	25801769
Pubmed	Polymorphism of TAS2R3, TAS2R5, TAS2R19, and TAS2R50 genes and bitter food intake frequency inelderly woman.	TAS2R5 TAS2R19	4.05e-05	4	91	2	32227702
Pubmed	Expression of connexin genes in the human retina.	GJA9 GJA10	4.05e-05	4	91	2	20979653
Pubmed	Increased expression of LXR alpha, ABCG5, ABCG8, and SR-BI in the liver from normolipidemic, nonobese Chinese gallstone patients.	SCARB1 ABCG5	4.05e-05	4	91	2	18007013
Pubmed	A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.	HDAC5 BCORL1	6.74e-05	5	91	2	17379597
Pubmed	Newly identified paralogous groups on mouse chromosomes 5 and 11 reveal the age of a T-box cluster duplication.	HNF1A NOS2	6.74e-05	5	91	2	9119393
Pubmed	Interplay between cystic fibrosis transmembrane regulator and gap junction channels made of connexins 45, 40, 32 and 50 expressed in oocytes.	GJA5 GJA8	6.74e-05	5	91	2	17546509
Pubmed	Genome-wide searching of rare genetic variants in WTCCC data.	NDST3 M1AP NOD2	8.13e-05	32	91	3	20549515
Pubmed	Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues.	GJA9 GJA10	1.01e-04	6	91	2	12881038
Pubmed	Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle.	NOS2 ADCY5	1.01e-04	6	91	2	24944202
Pubmed	A probabilistic classifier for olfactory receptor pseudogenes.	OR5L1 OR5AR1 OR2AG1	1.07e-04	35	91	3	16939646
Pubmed	Personal receptor repertoires: olfaction as a model.	OR5L1 OR5AR1 OR2AG1	1.37e-04	38	91	3	22908908
Pubmed	Genetic diseases and gene knockouts reveal diverse connexin functions.	GJA5 GJA8	1.41e-04	7	91	2	10099690
Pubmed	Functional significance of gap junctional coupling in preimplantation development.	GJA5 GJA10	1.41e-04	7	91	2	11967204
Pubmed	Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis.	HNF1A SCARB1 ABCG5	1.72e-04	41	91	3	19878569
Pubmed	Diverse functions of vertebrate gap junctions.	GJA5 GJA8	1.88e-04	8	91	2	9861669
Pubmed	Positional cloning of the combined hyperlipidemia gene Hyplip1.	GJA8 CD160	2.41e-04	9	91	2	11753387
Pubmed	Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.	CELSR1 DCHS1	2.41e-04	9	91	2	28705793
Pubmed	A Conserved LIR Motif in Connexins Mediates Ubiquitin-Independent Binding to LC3/GABARAP Proteins.	GJA5 GJA8	2.41e-04	9	91	2	32272685
Pubmed	Gap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammals.	GJA5 GJA8	2.41e-04	9	91	2	14595769
Pubmed	Irinotecan pathway genotype analysis to predict pharmacokinetics.	ABCC1 CYP3A4	3.01e-04	10	91	2	12960109
Pubmed	Multiple members of the connexin gene family participate in preimplantation development of the mouse.	GJA5 GJA8	3.67e-04	11	91	2	8631157
Pubmed	Complex transcription and splicing of odorant receptor genes.	OR11A1 OR2B3	3.67e-04	11	91	2	12637542
Pubmed	mRNA expression pattern of multiple members of connexin gene family in normal and abnormal fetal gonads in mouse.	GJA5 GJA8	3.67e-04	11	91	2	15255617
Pubmed	Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development.	GJA5 HDAC5	3.67e-04	11	91	2	23603510
Pubmed	Pharmacogenetic predictors of adverse events and response to chemotherapy in metastatic colorectal cancer: results from North American Gastrointestinal Intergroup Trial N9741.	ABCC1 CYP3A4	5.18e-04	13	91	2	20530282
Pubmed	YAC/P1 contigs defining the location of 56 microsatellite markers and several genes across a 3.4-cM interval on mouse chromosome 11.	TMEM97 NOS2	5.18e-04	13	91	2	7626882
Pubmed	Genetic variation in 3-hydroxy-3-methylglutaryl CoA reductase modifies the chemopreventive activity of statins for colorectal cancer.	CYP3A4 ABCG5 NOD2	5.86e-04	62	91	3	20403997
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	HNF1A SCARB1 ABCG5 DNAH11	6.00e-04	146	91	4	20686565
Pubmed	Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists.	TRIT1 NPAS2	6.04e-04	14	91	2	20095854
Pubmed	Exome sequencing links corticospinal motor neuron disease to common neurodegenerative disorders.	ENTPD1 ERLIN1	6.95e-04	15	91	2	24482476
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	HNF1A CYP3A4 ABCG5	7.04e-04	66	91	3	20679960
Pubmed	Characterization of human colon cancer antigens recognized by autologous antibodies.	HDAC5 TDRD6	7.93e-04	16	91	2	9610721
Pubmed	Pharmacogenetic assessment of toxicity and outcome after platinum plus taxane chemotherapy in ovarian cancer: the Scottish Randomised Trial in Ovarian Cancer.	ABCC1 CYP3A4	7.93e-04	16	91	2	17925548
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR2AK2 OR2Z1 OR10D4P	9.82e-04	74	91	3	15081110
Pubmed	Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon.	HNF1A NOS2 NPAS2	9.82e-04	74	91	3	26332085
Pubmed	Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes.	HNF1A ERLIN1	1.38e-03	21	91	2	18940312
Pubmed	A novel family of mammalian taste receptors.	TAS2R5 TAS2R19	1.38e-03	21	91	2	10761934
Pubmed	The molecular receptive ranges of human TAS2R bitter taste receptors.	TAS2R5 TAS2R19	1.65e-03	23	91	2	20022913
Pubmed	Genomic variants in an inbred mouse model predict mania-like behaviors.	DNAH11 NPAS2	1.65e-03	23	91	2	29768498
Pubmed	Proteomics of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies ERGIC-32, a new cycling protein that interacts with human Erv46.	ANPEP ERGIC2	1.80e-03	24	91	2	15308636
Pubmed	Receptors for bitter and sweet taste.	TAS2R5 TAS2R19	1.95e-03	25	91	2	12139982
Pubmed	Molecular mechanisms of bitter and sweet taste transduction.	TAS2R5 TAS2R19	2.11e-03	26	91	2	11696554
Pubmed	Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.	TAS2R5 TAS2R19	2.28e-03	27	91	2	12581520
Pubmed	Discovery and refinement of loci associated with lipid levels.	HNF1A SCARB1 ABCG5 DNAH11	2.33e-03	211	91	4	24097068
Pubmed	Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer.	ABCC1 ANPEP	2.45e-03	28	91	2	20689807
Pubmed	Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.	TAS2R5 TAS2R19	2.45e-03	28	91	2	15744053
Interaction	SPSB4 interactions	CELSR1 RPS6KA5 FANCI DCHS1 NMT1 NOS2	6.84e-06	124	75	6	int:SPSB4
Cytoband	1q44	OR2AK2 OR2M7 OR2M2 OR2M5	7.10e-05	110	91	4	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2AK2 OR2M7 OR2M2 OR2M5	1.28e-04	128	91	4	chr1q44
Cytoband	1q21.1	GJA5 GJA8 CD160	2.62e-04	62	91	3	1q21.1
GeneFamily	Olfactory receptors, family 2	OR2AK2 OR2M7 OR2M2 OR2B3 OR2M5 OR2Z1 OR2AG1	2.19e-07	113	68	7	149
GeneFamily	Gap junction proteins	GJA9 GJA5 GJA8 GJA10	1.27e-06	22	68	4	314
GeneFamily	Olfactory receptors, family 10	OR10A3 OR10AD1 OR10K1 OR10J4 OR10D4P	4.85e-06	66	68	5	157
GeneFamily	Olfactory receptors, family 4	OR4K2 OR4K13 OR4K1 OR4D5	1.42e-03	129	68	4	151
ToppCell	facs-Marrow-KLS-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XCR1 ANPEP SCARB1 NCKIPSD TMEM97 ERLIN1	2.43e-06	190	90	6	c03c735a0ed850bf460a1847f5e2dd61753e577d
Disease	Chromosome 1q21.1 deletion syndrome	GJA5 GJA8	7.63e-06	2	82	2	cv:C2675897
Disease	CHROMOSOME 1q21.1 DELETION SYNDROME, 1.35-MB	GJA5 GJA8	7.63e-06	2	82	2	612474
Disease	Chromosome 1q21.1 Deletion Syndrome, 1.35-Mb	GJA5 GJA8	7.63e-06	2	82	2	C2675897
Disease	phenylalanylphenylalanine measurement	ABCC1 ANPEP	2.28e-05	3	82	2	EFO_0021131
Disease	Coronary heart disease	HNF1A ABCG5 DNAH11	4.01e-05	24	82	3	C0010068
Disease	pulse pressure measurement, anxiety	GJA9 GJA10	1.59e-04	7	82	2	EFO_0005230, EFO_0005763
Disease	familial Mediterranean fever (is_implicated_in)	CYP3A4 NOD2	2.71e-04	9	82	2	DOID:2987 (is_implicated_in)
Disease	CCL2 measurement	XCR1 NCKIPSD OR10J4 ADCY5	4.29e-04	126	82	4	EFO_0004749
Disease	HbA1c measurement	ABCC1 HNF1A OR10AD1 ADCY5 ABCG5 SLC25A37 MYO5C C2CD2L	5.79e-04	675	82	8	EFO_0004541
Disease	Arthritis, Psoriatic	NOS2 NOD2	6.79e-04	14	82	2	C0003872
Disease	Hepatitis C	CYP3A4 SCARB1	7.82e-04	15	82	2	C0019196
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	HNF1A KRT32 SCARB1 MERTK	7.85e-04	148	82	4	C0279702
Disease	Depressive disorder	NPY1R HDAC5 NOS2 ADCY5 NPAS2	1.28e-03	289	82	5	C0011581
Disease	Hypertensive disease	ABCC1 GJA5 NOS2 ADCY5	1.97e-03	190	82	4	C0020538
Disease	Dyslipidemias	ABCG5 DNAH11	2.02e-03	24	82	2	C0242339
Disease	Dyslipoproteinemias	ABCG5 DNAH11	2.02e-03	24	82	2	C0598784
Disease	middle cerebral artery infarction (biomarker_via_orthology)	HDAC5 NOS2 NOD2	2.24e-03	93	82	3	DOID:3525 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SHTSVTMEALLYKPI	ABR	226	Q12979
TVVSYLPLSHIAAQM	ACSBG2	266	Q5FVE4
DHTSQVMVPLYLFNT	BPIFB3	271	P59826
YLLPIVHSTKNMQTT	AGBL3	831	Q8NEM8
MFTISQVTPLHSGTY	CD160	96	O95971
QIIFVSSPSLVYMGH	GJA10	81	Q969M2
YHIMLPFITTFRSVQ	ERLIN1	51	O75477
MFQYFITVVPTKLHT	ERGIC2	246	Q96RQ1
VLATYMSHELVLATP	BCORL1	986	Q5H9F3
KPVVMEIFSLHYSTL	DNAH11	581	Q96DT5
HLMLYPVQFLSTTLN	GLDN	536	Q6ZMI3
VTEFHTTPKMSTYLL	ANPEP	266	P15144
HRPIINTPMVSTLVY	CELSR1	2366	Q9NYQ6
TIVPHSIFMLSFYLT	ADCY5	781	O95622
NYTSPLVAMHFTDVV	ATP1B4	306	Q9UN42
LYLFLVMHPSILSNS	NDST3	611	O95803
ITVVQLNTHLHTPMY	OR6K2	46	Q8NGY2
VYKILSSHMLVTDSP	NPAS2	141	Q99743
SITPVFHQEMLNYVL	NOS2	471	P35228
QNLVPHRSYVSTMIL	FANCI	351	Q9NVI1
FSQSLYQVMLLEHTP	DCHS1	2376	Q96JQ0
HMISFVDPLVTNYTV	TRIT1	81	Q9H3H1
TVIISLNQSLHVPMY	OR10A3	46	P58181
PMVLTVTSYVHILAT	OR10AD1	211	Q8NGE0
LMIFYVAPSAVHSQL	OR11A1	256	Q9GZK7
AIISSTRLHTPMYFF	OR10D4P	46	Q8NGN7
LCYTTTTVPHMLVNI	OR2B3	71	O76000
HTPMYFLLSQLSIVD	OR2AK2	71	Q8NG84
ASTFYVIMPSHSLTL	M1AP	381	Q8TC57
SFYNVHTQTPLLDLM	NMT1	421	P30419
SVMIFNTSALPHLYQ	MERTK	331	Q12866
YMRSLHQFSETPILS	ITPRID1	101	Q6ZRS4
VLTMTPDYQSHFRTI	KRT32	136	Q14532
SSVLSFIMYELATHP	CYP3A4	311	P08684
SVMETFLLYQHFRPT	MAP3K6	476	O95382
LDTQLHTPMYFLLSQ	OR2M2	51	Q96R28
LDTQLHTPMYFLLSQ	OR2M5	51	A3KFT3
LDTQLHTPMYFLLSQ	OR2M7	51	Q8NG81
VDSRLHTPMYFLLSQ	OR2Z1	51	Q8NG97
IVIISFDSHLNSPMY	OR4K1	46	Q8NGD4
HSPMYFLLTNLSIID	OR4K2	56	Q8NGD2
LVTVTFDSLLHTPMY	OR4K13	46	Q8NH42
GTIIFMYLQPSSSHS	OR5B3	251	Q8NH48
ATHMLNVAVPIATYS	GPR153	51	Q6NV75
QYTHTGLLPQTMLIT	HNF1A	511	P20823
MQIFAPYVHLVSITV	GDPD4	101	Q6W3E5
ILYTMLSGQVPFQSH	RPS6KA5	611	O75582
ASYTQILLTVLHMPS	OR2AG1	216	Q9H205
PLSHSTYVFLMVLFS	ENTPD1	471	P49961
HLTAMISTCVNPIFY	NPY1R	306	P25929
TMHAFPYIKTRISVI	DOCK8	1921	Q8NF50
SMETYHVTLTLPPTQ	C2CD2L	176	O14523
QVIFVSSPSLVYMGH	GJA9	81	P57773
QIIFVSTPSLVYMGH	GJA5	81	P36382
QIIFVSTPSLMYVGH	GJA8	81	P48165
VVTMSLEHYNQPTSL	CACNA1I	1501	Q9P0X4
LFSMAPYVLNVTAVH	EBI3	96	Q14213
AYALHVLPFSVVATM	ABCG5	466	Q9H222
SYIALITMAILQSPH	FOXD4L1	111	Q9NU39
EYLTAFRTVVMPIAH	HDAC5	936	Q9UQL6
TLYQHVMFVFPVTLL	CH25H	91	O95992
LMHIYSQPIAILQTS	FAM171B	531	Q6P995
ISQPLHYTLIMNQTV	OR4D5	126	Q8NGN0
LHTPMYFFLSVLSIS	OR10J4	56	P0C629
ISTIVLDRALHTPMY	OR10K1	46	Q8NGX5
ISITILDSHLHTPMY	OR13F1	46	Q8NGS4
TRILVTHSMSYLPQV	ABCC1	821	P33527
AHYPVVVNAMTLFET	MCM9	36	Q9NXL9
TVAIMYPSFHSFILI	TAS2R19	266	P59542
RIFAMSHQTIPSVYI	GFM2	6	Q969S9
IMPGFKTTVYVSHIN	TDRD6	1301	O60522
IALIQVSSRLHTPMY	OR5L1	46	Q8NGL2
YTTQLTMNIPFQSIH	SLC25A37	201	Q9NYZ2
YPSTGILSVIFSMHV	ST3GAL1	266	Q11201
TLHTFYTQLVLMPKV	SCARB1	426	Q8WTV0
IILITTDTQLHTPMY	OR5AR1	46	Q8NGP9
TLFQLSHVTLMLSVY	SYT14P1	126	Q58G82
LSLMHAIVRTTPYLQ	NCKIPSD	661	Q9NZQ3
HLVYIMASPFSITSK	TAS2R5	231	Q9NYW4
TIMTIHRYLSVVSPL	XCR1	121	P46094
EYMPTFIQQTFLTLH	ZNF383	146	Q8NA42
SPKTTTDMYLLILQH	NOD2	506	Q9HC29
IYMETSLVPSSIIAH	RBAK	121	Q9NYW8
VYSFMCQHSLPSLIT	TMEM104	281	Q8NE00
LPYTLSMVATIDSQH	VWA5A	176	O00534
HTMTTLIPILSTFLF	TMEM97	106	Q5BJF2
ASLEPHVIMYILSSI	XPO7	906	Q9UIA9
HTITLLSFTIVSLMY	PTDSS1	41	P48651
LPFIQMVHYISTTSL	USP54	176	Q70EL1
SLYLLMETLNATTPH	MYO5C	631	Q9NQX4
EHYQRFVSVPIIMSS	N4BP2	571	Q86UW6
SIQSALILETPHMYF	N4BP2	671	Q86UW6