Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	ATRX MCM9 ERCC6L2 CHD7 DSCC1	8.36e-05	127	70	5	GO:0008094
GeneOntologyMolecularFunction	helicase activity	ATRX MCM9 ERCC6L2 CHD7 DSCC1	2.33e-04	158	70	5	GO:0004386
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	ATRX ERCC6L2 CHD7	2.94e-04	37	70	3	GO:0140658
Domain	SNF2_N	ATRX ERCC6L2 CHD7	2.31e-04	32	70	3	IPR000330
Domain	SNF2_N	ATRX ERCC6L2 CHD7	2.31e-04	32	70	3	PF00176
Domain	-	SAFB SLTM	2.78e-03	21	70	2	1.10.720.30
Domain	SAP	SAFB SLTM	3.05e-03	22	70	2	PF02037
Domain	Pentatricopeptide_repeat	DENND4A KLC1	3.33e-03	23	70	2	IPR002885
Domain	SAP	SAFB SLTM	3.33e-03	23	70	2	SM00513
Domain	SAP	SAFB SLTM	3.93e-03	25	70	2	PS50800
Domain	SAP_dom	SAFB SLTM	3.93e-03	25	70	2	IPR003034
Domain	-	ATRX CLPB HS2ST1 MCM9 ERCC6L2 NAV1 CHD7 RAB27A	6.63e-03	746	70	8	3.40.50.300
Domain	Helicase_C	ATRX ERCC6L2 CHD7	7.58e-03	107	70	3	PF00271
Domain	HELICc	ATRX ERCC6L2 CHD7	7.58e-03	107	70	3	SM00490
Domain	DNA/RNA_helicase_DEAH_CS	ERCC6L2 CHD7	7.61e-03	35	70	2	IPR002464
Domain	Helicase_C	ATRX ERCC6L2 CHD7	7.77e-03	108	70	3	IPR001650
Domain	HELICASE_CTER	ATRX ERCC6L2 CHD7	7.97e-03	109	70	3	PS51194
Domain	HELICASE_ATP_BIND_1	ATRX ERCC6L2 CHD7	7.97e-03	109	70	3	PS51192
Domain	DEXDc	ATRX ERCC6L2 CHD7	7.97e-03	109	70	3	SM00487
Domain	Helicase_ATP-bd	ATRX ERCC6L2 CHD7	8.17e-03	110	70	3	IPR014001
Domain	Ank_2	CLPB ANKRD11 ANKDD1B NOTCH1	8.66e-03	215	70	4	PF12796
Domain	DEAH_ATP_HELICASE	ERCC6L2 CHD7	8.92e-03	38	70	2	PS00690
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	RNMT NRDC ATRX SYNJ1 AOPEP SLTM LRP2 ARHGEF18 CHD7 TSTD2 WNK1 ARHGAP21 KNOP1	2.65e-07	1084	71	13	11544199
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	CCNT1 ELOB SAFB ATRX SYNJ1 KDM3B WNK1 AP3D1 ARHGAP21 KLC1 KNOP1 HDLBP	3.92e-07	934	71	12	33916271
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAPK8IP1 KCNA4 SYNJ1 ARVCF NT5C2 MCC NAV1 ARHGEF18 CHD7 ARHGAP21 KLC1 LRRFIP1	5.41e-07	963	71	12	28671696
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	CCNT1 NAA25 RNMT GZF1 ANKRD11 CHD7 TSTD2 RAB27A MED13	1.46e-06	536	71	9	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	CCNT1 NAA25 RNMT GZF1 ANKRD11 CHD7 TSTD2 RAB27A MED13	1.51e-06	538	71	9	10512203
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CCNT1 RSBN1 ELOB GZF1 ATRX CLPB ANKRD11 BUD13 CHD7 TRIP4 MED13 KNOP1 HDLBP MICU1	1.70e-06	1497	71	14	31527615
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FZR1 SYNJ1 ARVCF ANKRD11 KDM3B NAV1 ZZEF1 WNK1 AP3D1 ARHGAP21 MED13 NOTCH1	2.27e-06	1105	71	12	35748872
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CCNT1 RSBN1 ZNF777 SAFB ATRX SLTM ANKRD11 BUD13 CHD7 KNOP1 HDLBP	3.56e-06	954	71	11	36373674
Pubmed	Notch interferes with the scaffold function of JNK-interacting protein 1 to inhibit the JNK signaling pathway.	MAPK8IP1 NOTCH1	4.11e-06	2	71	2	16179393
Pubmed	Characterization of the binding mode of JNK-interacting protein 1 (JIP1) to kinesin-light chain 1 (KLC1).	MAPK8IP1 KLC1	4.11e-06	2	71	2	30026235
Pubmed	mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription.	RNMT RAB27A	4.11e-06	2	71	2	29719263
Pubmed	Phosphorylation of KLC1 modifies interaction with JIP1 and abolishes the enhanced fast velocity of APP transport by kinesin-1.	MAPK8IP1 KLC1	4.11e-06	2	71	2	29093025
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DENND4A NRDC ATRX ARVCF SLTM KDM3B ZZEF1 AP3D1 ARHGAP21	6.99e-06	650	71	9	38777146
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FSIP2 DENND4A SYNJ1 PLEKHA3 ANKRD11 KDM3B NAV1 WNK1 ARHGAP21 KLC1	9.69e-06	861	71	10	36931259
Pubmed	Clinicopathological analysis of ATRX, DAXX and NOTCH receptor expression in angiosarcomas.	ATRX NOTCH1	1.23e-05	3	71	2	28796347
Pubmed	Molecular cloning of a novel human I-mfa domain-containing protein that differently regulates human T-cell leukemia virus type I and HIV-1 expression.	CCNT1 MDFIC	1.23e-05	3	71	2	10671520
Pubmed	A molecular dynamics study of the binary complexes of APP, JIP1, and the cargo binding domain of KLC.	MAPK8IP1 KLC1	1.23e-05	3	71	2	27891669
Pubmed	JIP1 mediates anterograde transport of Rab10 cargos during neuronal polarization.	MAPK8IP1 KLC1	1.23e-05	3	71	2	24478353
Pubmed	Homozygous loss-of-function mutations in FSIP2 cause male infertility with asthenoteratospermia.	FSIP2 AKAP3	1.23e-05	3	71	2	30745215
Pubmed	The human I-mfa domain-containing protein, HIC, interacts with cyclin T1 and modulates P-TEFb-dependent transcription.	CCNT1 MDFIC	1.23e-05	3	71	2	12944466
Pubmed	Phosphorylation of kinesin light chain 1 at serine 460 modulates binding and trafficking of calsyntenin-1.	MAPK8IP1 KLC1	1.23e-05	3	71	2	21385839
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	CCNT1 SAFB ATRX SLTM KNOP1	1.35e-05	148	71	5	32538781
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	SAFB ATRX CLPB PLEKHA3 MCM9 SLTM NT5C2 ANKRD11 WNK1 MED13 HDLBP MICU1	1.45e-05	1327	71	12	32694731
Pubmed	Developmental regulators containing the I-mfa domain interact with T cyclins and Tat and modulate transcription.	CCNT1 MDFIC	2.46e-05	4	71	2	17289077
Pubmed	Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease.	MAPK8IP1 KLC1	2.46e-05	4	71	2	19491104
Pubmed	Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis.	KCNA4 NOTCH1	2.46e-05	4	71	2	9169836
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MCC ARHGEF18 CHD7 WNK1 NOTCH1 KLC1 LRRFIP1	2.83e-05	430	71	7	35044719
Pubmed	A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.	FSIP2 AKAP3	4.09e-05	5	71	2	12606363
Pubmed	Amyloid beta protein precursor (AbetaPP), but not AbetaPP-like protein 2, is bridged to the kinesin light chain by the scaffold protein JNK-interacting protein 1.	MAPK8IP1 KLC1	4.09e-05	5	71	2	12893827
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	CCNT1 CLPB SLTM ARHGEF18 CHD7	5.33e-05	197	71	5	20811636
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MAPK8IP1 NAA25 ATRX CLPB SYNJ1 LRP2 USPL1 ARHGAP21 MED13 LRRFIP1 MICU1	5.62e-05	1285	71	11	35914814
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KIAA1210 FZR1 ZNF777 NAV1	6.05e-05	103	71	4	10574462
Pubmed	ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway.	ALDH1A1 NOTCH1	6.13e-05	6	71	2	24671051
Pubmed	Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules.	MAPK8IP1 KLC1	6.13e-05	6	71	2	11238452
Pubmed	Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.	CCNT1 ELOB	6.13e-05	6	71	2	17690245
Pubmed	Remodeling of repolarization and arrhythmia susceptibility in a myosin-binding protein C knockout mouse model.	KCNA4 KCNJ2	8.57e-05	7	71	2	28646025
Pubmed	ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.	SAFB ATRX CHD7 SMOC2	8.68e-05	113	71	4	34474245
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SYNJ1 KDM3B SNRK CHD7 WNK1	9.97e-05	225	71	5	12168954
Pubmed	Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis.	RSBN1 NAA25	1.14e-04	8	71	2	19565500
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	MCC KDM3B NAV1 AKAP3 ARHGEF18 CHD7 WNK1 TRIP4	1.24e-04	733	71	8	34672954
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAPK8IP1 SAFB NRDC SYNJ1 ARVCF NAV1 AP3D1 ARHGAP21 KLC1 LRRFIP1 HDLBP	1.46e-04	1431	71	11	37142655
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	SAFB KDM3B BUD13 KNOP1	1.49e-04	130	71	4	35545047
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SYNJ1 ARVCF SHB ARHGAP21 NOTCH1 LRRFIP1 HDLBP	1.56e-04	565	71	7	25468996
Pubmed	Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro.	RNMT ZNF264 ZZEF1	1.68e-04	52	71	3	9455477
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	FSIP2 SAFB KDM3B WNK1 KLC1 HDLBP	1.68e-04	399	71	6	35987950
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	ELOB NRDC NT5C2 KDM3B CHORDC1 ZZEF1 WNK1 AP3D1 KLC1 LRRFIP1 HDLBP	1.69e-04	1455	71	11	22863883
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SAFB ATRX KDM3B BUD13 CHD7 MED13 LRRFIP1 HDLBP	1.79e-04	774	71	8	15302935
Pubmed	Interaction of a mitogen-activated protein kinase signaling module with the neuronal protein JIP3.	MAPK8IP1 KLC1	1.83e-04	10	71	2	10629060
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	ATRX SYNJ1 NAV1 CHD7 DSCC1 WNK1 HDLBP	1.99e-04	588	71	7	38580884
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATRX AOPEP KIZ HS2ST1 SHB NT5C2 ANKRD11 NAV1 ARHGEF18 SMOC2 MICU1	2.06e-04	1489	71	11	28611215
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	SYNJ1 LRP2 NAV1 CHD7 ARHGAP21 KLC1	2.15e-04	418	71	6	34709266
Pubmed	Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover.	CCNT1 NOTCH1	2.23e-04	11	71	2	15546612
Pubmed	Synaptic vesicle trafficking and Parkinson's disease.	SYNJ1 RAB27A	2.23e-04	11	71	2	21563316
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CCNT1 RNMT KDM3B CHD7 MED13	2.25e-04	268	71	5	33640491
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	FSIP2 CCNT1 ATRX KDM3B CHD7 MRGBP KNOP1	2.44e-04	608	71	7	36089195
Pubmed	Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligase.	KCNA4 ARVCF PDZRN4	2.57e-04	60	71	3	22889411
Pubmed	Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes.	ELOB NOTCH1	2.68e-04	12	71	2	21119685
Pubmed	Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.	MAPK8IP1 KLC1	2.68e-04	12	71	2	16301330
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	ATRX ANKRD11 KDM3B CHD7	3.07e-04	157	71	4	30186101
Pubmed	Functional interaction of megalin with the megalinbinding protein (MegBP), a novel tetratrico peptide repeat-containing adaptor molecule.	MAPK8IP1 LRP2	3.16e-04	13	71	2	12508107
Pubmed	Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.	GZF1 HS2ST1 SHB ARHGEF18 AP3D1	3.39e-04	293	71	5	31741433
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ELOB SYNJ1 KIZ SHB LRP2 CHORDC1 ARHGAP21 KLC1	3.45e-04	853	71	8	28718761
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	MAPK8IP1 ARVCF ARHGAP21	3.56e-04	67	71	3	29254152
Pubmed	Disappearance of centroacinar cells in the Notch ligand-deficient pancreas.	ALDH1A1 NOTCH1	3.68e-04	14	71	2	25919081
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	FSIP2 ATRX ANKRD11 CCDC168	3.97e-04	168	71	4	30631154
Pubmed	A neurogenomics approach to gene expression analysis in the developing brain.	RNMT NRDC SNRK WNK1	4.15e-04	170	71	4	15582152
Pubmed	The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old age.	PHOX2A ALDH1A1	4.24e-04	15	71	2	18076286
Pubmed	FBXO45-MYCBP2 regulates mitotic cell fate by targeting FBXW7 for degradation.	MED13 NOTCH1	4.24e-04	15	71	2	31285543
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	SAFB ATRX CLPB SYNJ1 AP3D1 HDLBP	4.25e-04	475	71	6	31040226
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CCNT1 RSBN1 MCC LRP2 BUD13 MRGBP ZZEF1 TRIP4 KNOP1	4.37e-04	1116	71	9	31753913
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	RSBN1 GZF1 CLPB CHD7 MRGBP TRIP4 AP3D1 LRRFIP1 KNOP1 HDLBP	4.54e-04	1371	71	10	36244648
Pubmed	A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.	ANKRD11 CHD7	4.84e-04	16	71	2	10932191
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MAPK8IP1 SAFB KCNA4 SYNJ1 NAV1 SNRK LRRFIP1 HDLBP MICU1	5.06e-04	1139	71	9	36417873
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	DENND4A SHB CHORDC1 WNK1 ARHGAP21 MED13	5.40e-04	497	71	6	23414517
Pubmed	Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome.	ERCC6L2 TRIP4	5.48e-04	17	71	2	20873783
Pubmed	Delineating the HMGB1 and HMGB2 interactome in prostate and ovary epithelial cells and its relationship with cancer.	SAFB ATRX SLTM HDLBP	6.06e-04	188	71	4	29721183
Pubmed	Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.	MAPK8IP1 LRP2	6.16e-04	18	71	2	10827173
Pubmed	Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders.	SYNJ1 ARVCF	6.16e-04	18	71	2	27984743
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	ELOB NRDC CLPB FAM136A ZZEF1 MICU1	6.50e-04	515	71	6	31617661
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	DENND4A SAFB ATRX SHB ALDH1A1 USPL1 AP3D1 ARHGAP21 MED13 KNOP1	6.72e-04	1442	71	10	35575683
Pubmed	Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.	MAPK8IP1 KLC1	6.87e-04	19	71	2	15529118
Pubmed	Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells.	LRP2 NOTCH1	6.87e-04	19	71	2	34667084
Pubmed	An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.	KCNA4 ARVCF MCC	6.90e-04	84	71	3	15123239
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RNMT HS2ST1 KDM3B SNRK ZZEF1 MED13	7.47e-04	529	71	6	14621295
Pubmed	beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region.	PHOX2A ALDH1A1	7.62e-04	20	71	2	20532162
Pubmed	PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors.	NAV1 ARHGEF18	7.62e-04	20	71	2	32079660
Pubmed	Morphogenesis of the telencephalic commissure requires scaffold protein JNK-interacting protein 3 (JIP3).	MAPK8IP1 KLC1	7.62e-04	20	71	2	12897243
Pubmed	Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair.	CCNT1 SAFB ATRX KDM3B HDLBP	8.28e-04	357	71	5	37059091
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	ATRX SYNJ1 CHD7 AP3D1 NOTCH1	8.39e-04	358	71	5	32460013
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	ELOB ATRX CLPB ANKRD11 CHORDC1 TRIP4 AP3D1 KLC1 HDLBP MICU1	8.50e-04	1487	71	10	33957083
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	ATRX SLTM NT5C2	8.99e-04	92	71	3	15840729
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SYNJ1 KDM3B CHORDC1 KLC1 LRRFIP1 HDLBP	9.05e-04	549	71	6	38280479
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RSBN1 HS2ST1 MCM9 BUD13 AP3D1 LRRFIP1 KNOP1	9.09e-04	759	71	7	35915203
Pubmed	Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.	MAPK8IP1 KLC1	9.24e-04	22	71	2	15767678
Pubmed	Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.	KCNA4 KCNJ2	1.01e-03	23	71	2	16637659
Pubmed	p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas.	ARVCF ALDH1A1	1.01e-03	23	71	2	25523391
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	FZR1 SAFB SLTM NAV1 BUD13 LRRFIP1 KNOP1 HDLBP MICU1	1.02e-03	1257	71	9	36526897
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	CCNT1 ELOB SAFB RNMT ATRX SLTM KDM3B MED13	1.07e-03	1014	71	8	32416067
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ARVCF SHB NAV1 FYB1 ARHGAP21 NOTCH1	1.09e-03	569	71	6	30639242
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	RNMT LRP2 NOTCH1	1.18e-03	101	71	3	23382219
Cytoband	9q22.32	AOPEP ERCC6L2	8.07e-04	27	71	2	9q22.32
Cytoband	12p13.3	AKAP3 WNK1	9.97e-04	30	71	2	12p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr15q22	DENND4A SLTM TRIP4	1.15e-03	132	71	3	chr15q22
Cytoband	16p12.3	ELOB KNOP1	1.28e-03	34	71	2	16p12.3
Cytoband	3p22.1	KLHL40 SNRK	1.77e-03	40	71	2	3p22.1
Cytoband	15q22.31	DENND4A TRIP4	1.95e-03	42	71	2	15q22.31
Cytoband	Ensembl 112 genes in cytogenetic band chr9q22	AOPEP ERCC6L2 TSTD2	3.74e-03	200	71	3	chr9q22
Cytoband	19p13.3	FZR1 ARHGEF18 AP3D1	6.00e-03	237	71	3	19p13.3
Cytoband	2q37.3	LRRFIP1 HDLBP	6.40e-03	77	71	2	2q37.3
Coexpression	GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	CCNT1 ZNF777 ANKRD11 CHORDC1 USPL1 ARHGAP21 MED13	1.19e-06	200	71	7	M7531
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_3DY_NEGATIVE	CCNT1 RSBN1 NAA25 RNMT ATRX SNRK CHORDC1 USPL1	6.23e-06	363	71	8	M41103
Coexpression	GSE11961_PLASMA_CELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN	FZR1 ZNF777 MAP10 TRIP4 KNOP1 MICU1	1.69e-05	199	71	6	M9393
Coexpression	GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN	MDFIC SYNJ1 AOPEP CHD7 RAB27A NOTCH1	1.74e-05	200	71	6	M6240
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FSIP2 AKAP3 ANKDD1B CCDC168	3.37e-06	64	71	4	bf923a66b17e717b8d3817b9d0e201b82a7e4a88
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FSIP2 AKAP3 ANKDD1B CCDC168	3.37e-06	64	71	4	a3e852600c53b11175eb579e92962fa711f5678b
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Tox-Inhibitory_Gad1Gad2_Cplx3.Tox_(Interneuron,_lacunosum_oriens1?)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FSIP2 AKAP3 ANKDD1B CCDC168	3.37e-06	64	71	4	f8f43ad9354c786b418bac54614f96f50e8bea68
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	MDFIC ATRX ANKRD11 WNK1 AP3D1	1.54e-05	196	71	5	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	ATRX SLTM ANKRD11 LRRFIP1 HDLBP	1.61e-05	198	71	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	ATRX KIZ ANKRD11 FYB1 LRRFIP1	1.65e-05	199	71	5	19674e1eaeb51e4196d847cb62aa437c852951d3
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	RSBN1 RNMT HS2ST1 ANKRD11 TSTD2 WNK1 LRRFIP1	1.99e-06	188	71	7	4845_DN
Disease	Hermansky-Pudlak syndrome 1 (implicated_via_orthology)	AP3D1 RAB27A	1.66e-05	3	70	2	DOID:0060539 (implicated_via_orthology)
Disease	Metabolic Bone Disorder	ANKRD11 LRP2	4.96e-04	14	70	2	C0005944
Disease	platelet storage pool deficiency (implicated_via_orthology)	AP3D1 RAB27A	5.71e-04	15	70	2	DOID:2223 (implicated_via_orthology)
Disease	Osteopenia	ANKRD11 LRP2	5.71e-04	15	70	2	C0029453
Disease	FEV/FEC ratio	RNMT ARVCF SHB ERCC6L2 ANKRD11 MCC NAV1 ARHGEF18 AP3D1 HDLBP	6.15e-04	1228	70	10	EFO_0004713
Disease	Blood Platelet Disorders	FYB1 AP3D1	6.52e-04	16	70	2	C0005818
Disease	left atrial function	AOPEP PLEKHA3	1.13e-03	21	70	2	EFO_0004294
Disease	serum gamma-glutamyl transferase measurement	RNMT ATRX MCC ARHGAP21 MED13 KLC1 HDLBP MICU1	1.42e-03	914	70	8	EFO_0004532
Disease	obesity (implicated_via_orthology)	NT5C2 ALDH1A1 MED13 NOTCH1	1.73e-03	215	70	4	DOID:9970 (implicated_via_orthology)
Disease	Hypermetropia	ANKRD11 CHD7 ARHGAP21	1.91e-03	103	70	3	HP_0000540
Disease	platelet component distribution width	CLPB ARVCF ANKDD1B SMOC2 ZZEF1 WNK1 FYB1	2.07e-03	755	70	7	EFO_0007984
Disease	C-reactive protein measurement	RNMT AOPEP CCDC168 CHD7 ZZEF1 FYB1 ARHGAP21 HDLBP MICU1	2.14e-03	1206	70	9	EFO_0004458
Disease	Mental Retardation, X-Linked	ATRX ZNF674	2.16e-03	29	70	2	C1136249
Disease	Parkinsonism, Juvenile	SYNJ1 ALDH1A1	2.31e-03	30	70	2	C0752105

Protein segments in the cluster

Peptide	Gene	Start	Entry
FGDKKQLDSKGDCQK	BUD13	336	Q9BRD0
ESEDGAGKNEKSDKS	ARHGEF18	241	Q6ZSZ5
LKECGCESGFKDKSD	ANKRD11	976	Q6UB99
RDDASCFGGKKAKEE	ARVCF	611	O00192
SSDTICDLLGAKGKD	NT5C2	331	P49902
EDEEGEKKKSNFKCS	GZF1	306	Q9H116
DLIESGKKEGAKLEC	ALDH1A1	356	P00352
ICSKGEKDTSDKDGN	AOPEP	101	Q8N6M6
CEAAKKTKADDRGTD	CCNT1	261	O60563
TDGSGKESKQECEAE	CHD7	2196	Q9P2D1
KKGENSVSVDGKCSD	AP3D1	1121	O14617
IQEEKDKKGSDCSSL	DENND4A	926	Q7Z401
STDQLSEEKEKGACG	RAB27A	206	P51159
GCSAESKEKVLEGSK	PDZRN4	801	Q6ZMN7
GDLDASKEGKACVSE	KCNJ2	111	P63252
KKSQDGKGCLLDSSG	NOTCH1	2181	P46531
EAKKDKRSVGGCEKS	MAP10	446	Q9P2G4
LGSTAQGKCDKDNTE	MDFIC	26	Q9P1T7
GVKADDSQEAKGNKC	MAPK8IP1	621	Q9UQF2
DADKKGCSFLSKLAG	FSIP2	5211	Q5CZC0
GDKGKNKDEGDVCNH	MICU1	71	Q9BPX6
AEDSGGGDDKKSKTC	PDE6C	841	P51160
AKACCDVKGGKNELS	FYB1	516	O15117
SDSGCDPASKKLKGD	KDM3B	291	Q7LBC6
GDTCSVGKKDEEQAA	KNOP1	181	Q1ED39
DGAGAKEADKGTSKA	KLHL40	276	Q2TBA0
KCDGQKDCSDGSDEL	LRP2	3531	P98164
EQEVSSGCGDKSKKE	KIZ	536	Q2M2Z5
SGCGDKSKKENVAAD	KIZ	541	Q2M2Z5
KAKDATSDNGKDGLA	FZR1	76	Q9UM11
GDSCDSSEDKKSKNG	ATRX	1071	P46100
SSGSKDKPGKECADA	MCC	686	P23508
GDKDEQAVLCSKDKT	DSCC1	66	Q9BVC3
KDDQLLDDGKTLGEC	ELOB	46	Q15370
EEKDCGDAEGNSKKR	RNMT	91	O43148
SLDVLEAGDEGKKKC	KIAA1210	151	Q9ULL0
LTDGKGKTIDCKDAI	CLPB	476	Q9H078
CNDKAKDSIDAGSKE	FAM136A	86	Q96C01
GSCKFDKPKEDGQSN	CCDC168	5776	Q8NDH2
EAKDAGCEKNQDSLG	ERCC6L2	841	Q5T890
EEREECKGKQKDGTS	KLC1	431	Q07866
DTRGGNEKGKSKEDC	LRRFIP1	791	Q32MZ4
LTCEGDKKEEVSGSN	MCM9	1031	Q9NXL9
ESCDDSSKGGELKKP	NAV1	506	Q8NEY1
SCGTDLKHKDKQENG	RSBN1	206	Q5VWQ0
DAKNDLKSKAGKGES	SHB	251	Q15464
EEEDFGVKGKSKSAC	SYNJ1	1486	O43426
KSSKDKEKNSSDLGC	MRGBP	156	Q9NV56
KEKNSSDLGCKEGAD	MRGBP	161	Q9NV56
KQGDKKTFDECVAEG	HS2ST1	191	Q7LGA3
ANHKDGKKEDCVKGD	SLTM	301	Q9NWH9
DDKASCKESKTGNLD	MED13	806	Q9UHV7
GHRSKGLCDSAKKDD	SNRK	401	Q9NRH2
DDKCDRKDDAKKGDD	SAFB	516	Q15424
KSCDASLAELGDDKS	AKAP3	686	O75969
AGCDLKAVDKQGKTA	ANKDD1B	356	A6NHY2
EDNDEIKIGTSCKNG	CHORDC1	146	Q9UHD1
SGVKDGDCKKLTSEI	USPL1	286	Q5W0Q7
GCLGVAKEDGKADTK	SMOC2	411	Q9H3U7
AGAKKGEARCSSEDD	PHOX2A	161	O14813
LLSGANEGKCDLKEK	NRDC	611	O43847
DLCKDDFKTSKGGAH	TSTD2	236	Q5T7W7
DSQDDVCKGSKGSIK	PLEKHA3	31	Q9HB20
KEDLSQDTCPGDKGK	ZNF264	76	O43296
TLQACDVKGKEDKSG	ZZEF1	531	O43149
CFKKDEILDGQKSGD	TRIP4	86	Q15650
GTQSDKVTLKGAKDC	HDLBP	841	Q00341
ADGAQKEGKNKSEDA	WNK1	1866	Q9H4A3
GKETLKDESGQECKI	ZNF674	111	Q2M3X9
GRTGTNEKKIADCEK	ZNF777	211	Q9ULD5
EGDGDKLKACEVSKN	ARHGAP21	11	Q5T5U3
SLCAKEEKCQGKGDD	KCNA4	621	P22459
EEKCQGKGDDSETDK	KCNA4	626	P22459
FSKCKGDLLEVKDGN	NAA25	816	Q14CX7