Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

SPTBN4 KRT16 INA SPTB ADD1

7.57e-05130675GO:0005200
GeneOntologyMolecularFunctionactin filament binding

SPTBN4 MYH8 SYNE3 SPTB TNNI3 ADD1

1.13e-04227676GO:0051015
DomainSpectrin

SPTBN4 SYNE3 SPTB

7.10e-0523663PF00435
DomainSpectrin_bsu

SPTBN4 SPTB

7.35e-054662IPR016343
DomainSpectrin_repeat

SPTBN4 SYNE3 SPTB

1.44e-0429663IPR002017
DomainSpectrin/alpha-actinin

SPTBN4 SYNE3 SPTB

1.94e-0432663IPR018159
DomainSPEC

SPTBN4 SYNE3 SPTB

1.94e-0432663SM00150
DomainCalx_beta

ADGRV1 FREM1

4.36e-049662IPR003644
DomainSynN

STX11 STX1B

4.36e-049662SM00503
DomainCalx-beta

ADGRV1 FREM1

4.36e-049662PF03160
DomainSyntaxin

STX11 STX1B

6.63e-0411662PF00804
DomainSyntaxin_N

STX11 STX1B

7.93e-0412662IPR006011
DomainGRAM

TBC1D9B GRAMD1C

1.43e-0316662SM00568
DomainSyntaxin/epimorphin_CS

STX11 STX1B

1.43e-0316662IPR006012
DomainSYNTAXIN

STX11 STX1B

1.43e-0316662PS00914
DomainHEAT_REPEAT

CEP104 PSME4 UTP20

1.95e-0370663PS50077
DomainSNARE

STX11 STX1B

2.47e-0321662PF05739
DomainGRAM

TBC1D9B GRAMD1C

2.71e-0322662PF02893
DomainGRAM

TBC1D9B GRAMD1C

2.71e-0322662IPR004182
Domaint_SNARE

STX11 STX1B

2.71e-0322662SM00397
DomainActinin_actin-bd_CS

SPTBN4 SPTB

2.97e-0323662IPR001589
DomainACTININ_2

SPTBN4 SPTB

2.97e-0323662PS00020
DomainACTININ_1

SPTBN4 SPTB

2.97e-0323662PS00019
DomainT_SNARE

STX11 STX1B

3.78e-0326662PS50192
DomainT_SNARE_dom

STX11 STX1B

4.70e-0329662IPR000727
DomainPROTEIN_KINASE_ATP

FLT1 GRK5 SRPK1 PNCK CDC42BPB CASK

5.58e-03459666PS00107
DomainDNA/RNA_helicase_DEAH_CS

SMARCA5 DHX37

6.79e-0335662IPR002464
DomainProt_kinase_dom

FLT1 GRK5 SRPK1 PNCK CDC42BPB CASK

7.54e-03489666IPR000719
DomainPROTEIN_KINASE_DOM

FLT1 GRK5 SRPK1 PNCK CDC42BPB CASK

7.83e-03493666PS50011
DomainDEAH_ATP_HELICASE

SMARCA5 DHX37

7.97e-0338662PS00690
PathwayBIOCARTA_PDZS_PATHWAY

PCLO ADD1 CASK

3.93e-0518533M22001
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CEP104 SPTBN4 AP1AR MYH8 SET SMARCA5 SF3B3 KRT16 MIA2 INA PCLO GRK5 RBM5 SLC17A6

5.19e-071442671435575683
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

GTPBP2 CCDC88A KRT16 RBM5 RNF213 CCT7 CDC42BPB ZMAT1 ADD1 CASK

2.30e-06777671035844135
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

SET SMARCA5 SF3B3 KRT16 MIA2 AGL TIMM50 MRPS27 HTATSF1 SRPK1 CCT7 MCM6 PLRG1

2.59e-061415671328515276
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SET SMARCA5 SF3B3 VPS33B DHX37 PCLO TIMM50 MRPS27 RBM5 UTP20 CCT7 MCM6 PLRG1

2.80e-061425671330948266
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ENPP6 SPTBN4 MAPK8IP1 SF3B3 KRT16 INA PCLO SPTB CCT7 CDC42BPB STX1B ADD1 CASK

2.93e-061431671337142655
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SPTBN4 PLEKHG4B SENP1 INPP5A TM9SF4 POLG SPTB RBM5 RNF213 ADGRV1 CDC42BPB ZMAT1 CASK

4.52e-061489671328611215
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SET SMARCA5 SF3B3 DHX37 TIMM50 MRPS27 RBM5 UTP20 SRPK1 PLRG1

4.92e-06847671035850772
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

SET SF3B3 AGL HTATSF1 RNF213 CCT7 MCM6 ADGRV1

4.97e-0649567828581483
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

SMARCA5 VPS33B DHX37 AGL TIMM50 MRPS27 HTATSF1 UTP20 MCM6

8.14e-0670467929955894
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

LENG8 SET SMARCA5 RBM5 SRPK1 CDC42BPB

9.19e-0625167631076518
Pubmed

ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.

SET SMARCA5 SF3B3 HTATSF1 MCM6

1.09e-0515067528242625
Pubmed

A new spectrin, beta IV, has a major truncated isoform that associates with promyelocytic leukemia protein nuclear bodies and the nuclear matrix.

SPTBN4 SPTB

1.10e-05367211294830
Pubmed

RNA Helicase DHX37 Facilitates Liver Cancer Progression by Cooperating with PLRG1 to Drive Superenhancer-Mediated Transcription of Cyclin D1.

DHX37 PLRG1

1.10e-05367235290436
Pubmed

Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity.

SPTBN4 SPTB

1.10e-05367232052742
Pubmed

β spectrin-dependent and domain specific mechanisms for Na+ channel clustering.

SPTBN4 SPTB

1.10e-05367232425157
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

LENG8 SET SMARCA5 SF3B3 TIMM50 MRPS27 SRPK1 CCT7 PLRG1

1.10e-0573167929298432
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

CCDC88A MIA2 VPS33B SRPK1 CCT7 MCM6 MFN1

1.19e-0539967737536630
Pubmed

Identification of the spectrin subunit and domains required for formation of spectrin/adducin/actin complexes.

SPTB ADD1

2.19e-0546728663089
Pubmed

Adducin: structure, function and regulation.

SPTB ADD1

2.19e-05467210950304
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SENP1 CCDC88A SYNE3 SF3B3 TIMM50 MRPS27 HTATSF1 SRPK1 CDC42BPB PLRG1 ADD1 CASK

2.42e-051487671233957083
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

SET SF3B3 TIMM50 MRPS27 HTATSF1 SRPK1 CCT7 CDC42BPB CASK

2.44e-0580967932129710
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

SMARCA5 SF3B3 KRT16 HTATSF1 SRPK1 CCT7 MCM6

2.62e-0545167736168627
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SMARCA5 SF3B3 KRT16 DHX37 TIMM50 MRPS27 UTP20 SRPK1 CCT7 PLRG1 ADD1

2.64e-051257671136526897
Pubmed

Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations.

POLG MFN1

3.64e-05567220403324
Pubmed

LINKIN, a new transmembrane protein necessary for cell adhesion.

SET SF3B3 TIMM50 MRPS27 HTATSF1 SRPK1 CCT7

3.89e-0548067725437307
Pubmed

Dynamic protein-protein interaction wiring of the human spliceosome.

SF3B3 RBM5 HTATSF1 SRPK1 PLRG1

4.03e-0519767522365833
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SET SMARCA5 SF3B3 KRT16 INA DHX37 MRPS27 RBM5 PLRG1 CASK

4.04e-051082671038697112
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

SMARCA5 RNF213 UTP20 SRPK1 PLRG1 ADD1

4.42e-0533267625693804
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

SET SMARCA5 INA PCLO MRPS27 CDC42BPB CASK

4.90e-0549867736634849
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SMARCA5 SF3B3 PSME4 VPS33B DHX37 TIMM50 UTP20 SRPK1 CCT7 MCM6 PLRG1

5.15e-051353671129467282
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ENPP6 SET SMARCA5 SENP1 GTPBP2 SF3B3 TIMM50 MCC RNF213 CRACR2B

5.24e-051116671031753913
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

LENG8 SET SMARCA5 SF3B3 HTATSF1 CCT7 ADD1

5.42e-0550667730890647
Pubmed

Deletion of Inpp5a causes ataxia and cerebellar degeneration in mice.

INPP5A SLC17A6

5.46e-05667226051944
Pubmed

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.

POLG MFN1

5.46e-05667231358769
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

SET SMARCA5 SF3B3 TM9SF4 AGL TIMM50 HTATSF1 RNF213 CCT7 MCM6 PLRG1

5.65e-051367671132687490
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

LENG8 SMARCA5 DHX37 AGL TIMM50 MRPS27 RBM5 SRPK1 CDC42BPB PLRG1 ADD1

5.80e-051371671136244648
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MAPK8IP1 CCDC88A INA PCLO TIMM50 MRPS27 CCT7 PALMD CDC42BPB STX1B

6.21e-051139671036417873
Pubmed

The RNA-binding protein HuR is a novel target of Pirh2 E3 ubiquitin ligase.

SET SMARCA5 SF3B3 MRPS27 HTATSF1

6.79e-0522067534091597
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

SMARCA5 SF3B3 INA MRPS27 SRPK1 CCT7 MCM6 PLRG1

6.81e-0571467828302793
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

SET SMARCA5 SF3B3 KRT16 AGL MRPS27 HTATSF1 SRPK1 CCT7 PLRG1

6.88e-051153671029845934
Pubmed

Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.

SF3B3 RBM5 HTATSF1 PLRG1

7.40e-0511567417332742
Pubmed

Adducin is an in vivo substrate for protein kinase C: phosphorylation in the MARCKS-related domain inhibits activity in promoting spectrin-actin complexes and occurs in many cells, including dendritic spines of neurons.

SPTB ADD1

7.63e-0576729679146
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

LENG8 SMARCA5 DHX37 RBM5 PLRG1 ADD1

8.04e-0537067622922362
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SPTBN4 MAPK8IP1 SENP1 CCDC88A INA MCC CDC42BPB ADD1 CASK

9.35e-0596367928671696
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

SET SF3B3 KRT16 DHX37 TIMM50 MRPS27 SRPK1 CCT7 PLRG1

9.95e-0597167933306668
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

LENG8 SMARCA5 VPS33B TIMM50 MCM6 ADD1 CASK

1.02e-0456067735241646
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

LENG8 SMARCA5 SF3B3 DHX37 TIMM50 RBM5 UTP20 MCM6 PLRG1

1.14e-0498967936424410
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

SENP1 MIA2 VPS33B POLG PCLO TIMM50 MRPS27 RNF213 CCT7 MFN1 CASK

1.26e-041496671132877691
Pubmed

An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye.

FLT1 SLC17A6

1.30e-04967230936473
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

SET SMARCA5 INA SRPK1 CCT7 MCM6 PLRG1 ADD1

1.32e-0478667829128334
Pubmed

A Compendium of RNA-Binding Proteins that Regulate MicroRNA Biogenesis.

SF3B3 DHX37 RBM5 UTP20 PLRG1

1.33e-0425467528431233
Pubmed

Structural basis of branch site recognition by the human spliceosome.

SF3B3 HTATSF1

1.63e-041067234822310
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

SMARCA5 SF3B3 KRT16 RBM5 HTATSF1 SRPK1 MCM6

1.64e-0460567728977666
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

SF3B3 AGL TIMM50 HTATSF1 SRPK1 MCM6 PLRG1

1.67e-0460767739147351
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

SET INA PCLO SPTB CCT7 STX1B ADD1

1.92e-0462167722794259
Pubmed

Voluntary wheel running reduces voluntary consumption of ethanol in mice: identification of candidate genes through striatal gene expression profiling.

CAMTA2 STX1B

1.99e-041167227063791
Pubmed

Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.

SPTBN4 SPTB

1.99e-041167217607528
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

DHX37 POLG TIMM50 CCT7

2.06e-0415067430154076
Pubmed

Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.

SMARCA5 SF3B3 INA MCM6 PLRG1

2.20e-0428367528533407
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

SMARCA5 SF3B3 TIMM50 CCT7 MCM6 PLRG1 ADD1

2.27e-0463867733239621
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

SET SMARCA5 SF3B3 INA TIMM50 MRPS27 SRPK1 CCT7 MCM6 PLRG1

2.27e-041335671029229926
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

LENG8 SENP1 CCDC88A INA VPS33B DHX37 TIMM50 CCT7

2.30e-0485367828718761
Pubmed

E2F4 cooperates with pRB in the development of extra-embryonic tissues.

FLT1 MCM6

2.38e-041267219433082
Pubmed

Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.

SMARCA5 SF3B3 DHX37 PLRG1

2.58e-0415967422751105
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

SET SF3B3 TIMM50 SRPK1 MCM6 PLRG1 MFN1

2.61e-0465367733742100
Pubmed

UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.

SET HTATSF1

2.81e-041367219836239
Pubmed

A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.

INA CASK

2.81e-041367215673434
Pubmed

alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.

SPTBN4 SPTB

2.81e-041367218796539
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

SF3B3 HTATSF1 SRPK1 CCT7 PLRG1

2.88e-0430067528561026
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

SF3B3 KRT16 DHX37 MRPS27 SRPK1 CCT7 PLRG1

3.28e-0467867730209976
Pubmed

Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development.

SPTBN4 SLC17A6

3.28e-041467236573432
Pubmed

Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.

CCDC88A TIMM50 MRPS27 CCT7

3.47e-0417267423184937
Pubmed

Cellular substrates and pro-apoptotic function of the human HtrA4 protease.

SF3B3 CCT7 MCM6 PLRG1

3.55e-0417367431470122
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

PLEKHG4B SMARCA5 INA TIMM50 RBM5 MCM6 PLRG1 CASK

3.71e-0491667832203420
Pubmed

Epileptiform activity and cognitive deficits in SNAP-25(+/-) mice are normalized by antiepileptic drugs.

STX1B SLC17A6

3.78e-041567223064108
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

MYH8 SET AGL SPTB RBM5 CDC42BPB

3.95e-0449767623414517
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

SMARCA5 SENP1 SF3B3 MCM6

4.30e-0418267432239614
Pubmed

ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.

SMARCA5 SF3B3 DHX37 SRPK1 CCT7

4.45e-0433067533301849
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

INA SPTB RNF213 CCT7

4.76e-0418767426460568
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

TSNAXIP1 SF3B3 DHX37 MRPS27 RBM5 HTATSF1 CASK

4.81e-0472367734133714
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

LENG8 SF3B3 TIMM50 MRPS27 CCT7 MCM6 PLRG1

4.89e-0472567727025967
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

LENG8 AP1AR SET GTPBP2 GRK5 SPTB RBM5 MCM6 FREM1

5.21e-04121567915146197
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

SF3B3 TIMM50 MRPS27 RNF213 CCT7

5.37e-0434467536282215
Pubmed

Circulating primitive erythroblasts establish a functional, protein 4.1R-dependent cytoskeletal network prior to enucleating.

SPTB ADD1

5.48e-041867228701737
Pubmed

Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles.

ANKRD13B CCDC88A

5.48e-041867229229865
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTBN4 SPTB

5.48e-041867212119179
Pubmed

In vitro nuclear interactome of the HIV-1 Tat protein.

SMARCA5 SF3B3 RNF213 MCM6

5.57e-0419567419454010
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

SF3B3 TIMM50 CCT7 MCM6

5.79e-0419767431620119
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

CCDC88A SF3B3 TIMM50 CCT7

6.24e-0420167425192599
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

TM9SF4 UTP20 SRPK1 CDC42BPB

6.36e-0420267433005030
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

CCDC88A SF3B3 INA RBM5 CCT7 PLRG1

6.78e-0455167634728620
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

MYH8 INA

6.79e-042067221689717
Pubmed

Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice.

SPTB ADD1

6.79e-042067218723693
Pubmed

Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1.

SMARCA5 MCM6

6.79e-042067218162579
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

SET SMARCA5 SF3B3 HTATSF1 RNF213 CCT7 MCM6 PLRG1

7.24e-04101467832416067
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

INA AGL HTATSF1 CCT7 STX1B ADD1

7.24e-0455867635063084
Pubmed

Molecular architecture of the human 17S U2 snRNP.

SF3B3 HTATSF1

7.50e-042167232494006
Pubmed

The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding.

SF3B3 CCT7

7.50e-042167227353360
Pubmed

Sox2 modulates the function of two distinct cell lineages in mouse skin.

PCLO SLC17A6

7.50e-042167223948231
Pubmed

Mechanisms of the RNA helicases DDX42 and DDX46 in human U2 snRNP assembly.

SF3B3 HTATSF1

7.50e-042167236797247
InteractionCIT interactions

SPTBN4 SMARCA5 SF3B3 INA CCDC42 NUP62CL PCLO SPTB MRPS27 RBM5 RNF213 UTP20 SRPK1 ADGRV1 GRAMD1C PLRG1

1.30e-0514506616int:CIT
InteractionMIRLET7E interactions

SF3B3 DHX37 RBM5 UTP20 PLRG1

2.54e-05106665int:MIRLET7E
InteractionFLT1 interactions

FLT1 SMARCA5 MRPS27 MMRN2 RNF213 SRPK1

2.64e-05179666int:FLT1
InteractionMIRLET7I interactions

SF3B3 DHX37 RBM5 UTP20 PLRG1

3.60e-05114665int:MIRLET7I
InteractionMIRLET7G interactions

SF3B3 DHX37 RBM5 UTP20 PLRG1

4.08e-05117665int:MIRLET7G
GeneFamilyEF-hand domain containing|Spectrins

SPTBN4 SPTB

1.10e-0474221113
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D9B GRAMD1C

4.04e-04134221146
GeneFamilySyntaxins

STX11 STX1B

6.19e-0416422818
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

SPTBN4 PLEKHG4B SPTB

1.21e-02206423682
GeneFamilyEF-hand domain containing

TBC1D9B MCC CRACR2B

1.42e-02219423863
ToppCelldroplet-Heart-4Chambers-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD CRACR2B

6.32e-061736759a04271c51fae34f547db3206f9ff5857686e45c
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l7|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TSNAXIP1 FLT1 MMRN2 PALMD CRACR2B

7.25e-06178675a3f95f0002f408b5b6c57e28b297b5b2737e919c
ToppCellEndothelial-A-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

FLT1 GRK5 MCC MMRN2 PALMD

7.45e-06179675138fd6ba6bdbd0ad01c574168addf720b67a0fea
ToppCelldroplet-Heart-4Chambers-21m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD CRACR2B

8.52e-06184675f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCellfacs-Trachea-nan-24m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD CRACR2B

8.75e-06185675dec60254204014083ff3b4aec0cc75410950a486
ToppCellfacs-Trachea-nan-24m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD CRACR2B

8.75e-06185675201465dc0d7aa0336a36d37805cae1155a5adfe1
ToppCellfacs-Trachea-nan-24m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD CRACR2B

8.75e-06185675334f006c3ef33338ff8d649309d3f448733a3a99
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 GRK5 MMRN2 CRACR2B CDC42BPB

9.21e-061876753548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 GRK5 MMRN2 CRACR2B CDC42BPB

9.21e-06187675f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 GRK5 MMRN2 CRACR2B CDC42BPB

9.21e-0618767581754e965848b718be20ee97ce072ce426938a69
ToppCelldroplet-Kidney-nan-3m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

9.45e-0618867567c04f446fa4528b13a381622e88eb1f314cc6d5
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

9.45e-0618867503a7f6538cfddc230c0eab10c3613929addd7e33
ToppCellfacs-Heart-LV-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

9.70e-06189675d424d2554595b2304219f7324406b401711af7c2
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

9.70e-06189675393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCellfacs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

9.70e-06189675bec57459ad4bab15b2532b57722549fec2e771fb
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 FLT1 MCC MMRN2 PALMD

9.95e-06190675632d5dc11765053366d61f0a0c7916111cea4f50
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

1.05e-05192675777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

1.05e-0519267560a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

1.05e-051926750f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCellfacs-BAT-Fat-3m-Endothelial-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

1.07e-05193675e340064cd146deac03f2d0fd43e2e218bb6057c9
ToppCellfacs-BAT-Fat-3m-Endothelial-endothelial_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

1.07e-05193675a211b386fd0fb9da9937361d29d90925a72c9715
ToppCellfacs-BAT-Fat-3m-Endothelial|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD CRACR2B

1.07e-051936753086c33f4d6fab66966818737f95ae4d6b2615b0
ToppCellEC-Arteriolar_ECs|World / Lineage and Cell class

FLT1 MMRN2 PALMD CRACR2B EMP2

1.10e-0519467538f0c52de252101d4bc8633af80002061635e487
ToppCelldroplet-Fat-Mat-18m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD CRACR2B

1.10e-0519467574d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCellfacs-Heart-RA-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B CDC42BPB

1.13e-0519567530c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 INPP5A MMRN2 CRACR2B

1.16e-0519667581900dcc9451ff6606ec940c16b559d73247590e
ToppCellILEUM-inflamed-(7)_Endothelial_cell-(7)_CD36+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FLT1 MCC MMRN2 EMP2 ADD1

1.19e-0519767566339b5aae3952f5c484c9dcb0cfb4fbd828d4cb
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FLT1 MCC MMRN2 PALMD EMP2

1.27e-05200675ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FLT1 GRK5 MCC MMRN2 PALMD

1.27e-05200675e90ca26643f8496bdd6672c327da9855490d1aa8
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons|GW23 / Sample Type, Dataset, Time_group, and Cell type.

MAPK8IP1 CCDC88A INA GRK5 PNCK

1.27e-05200675c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCellCOVID-19_Moderate-B_cell|World / disease group, cell group and cell class

CATSPERB CRACR2B GRAMD1C STX1B

5.75e-05139674b93e1da87d44e55d75e8cc1b87c2970645679c01
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FLT1 TIMM50 MCC PALMD

8.99e-051566746c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 MMRN2 PALMD ZMAT1

9.92e-0516067433050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLT1 MMRN2 RNF213 PALMD

1.07e-04163674d6f9b7280c44d120df5a72dfc2ebb26ffbb5752b
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP6 MMRN2 MCM6 PLRG1

1.12e-0416567462457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 SYNE3 MMRN2 PALMD

1.12e-04165674a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 SYNE3 MMRN2 PALMD

1.14e-041666748e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D231|Adult / Lineage, Cell type, age group and donor

FLT1 SPTB MCC PALMD

1.20e-04168674aca34c51758c65925ad24110294a72b2dea6db72
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 CRACR2B

1.20e-0416867406dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT1 MMRN2 MCM6 PALMD

1.20e-0416867432e4d82efaccf336d347e4063253c3635a3ec672
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 CRACR2B

1.20e-041686741002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellfacs-Heart-LV-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.22e-041696746a31a940a8474fb087d8fe7193a6974a72e0a014
ToppCellfacs-Heart-LV-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.22e-0416967439d627763abd57e53edb1169832b47cfb3e8c274
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 SYNE3 MMRN2 PALMD

1.22e-04169674c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCellfacs-Heart-LV-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.22e-04169674b85927a256790402e9fc12ebcadd83e4e2afd2ce
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT1 PALMD CDC42BPB STX1B

1.25e-04170674af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLT1 MMRN2 PALMD CRACR2B

1.28e-041716743112d15f2a28cf4a71992db4971d960716dc1264
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

FLT1 MMRN2 PALMD EMP2

1.34e-04173674ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 FLT1 MMRN2 PALMD

1.34e-04173674ad9777e4ae70b11676ec735eb6db91776ca0cb19
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

FLT1 MMRN2 PALMD EMP2

1.34e-0417367422200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LENG8 MAPK8IP1 KRT16 INA

1.37e-04174674207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell368C-Endothelial_cells-Endothelial-D|368C / Donor, Lineage, Cell class and subclass (all cells)

FLT1 MMRN2 PNCK PALMD

1.40e-04175674c4088b5f9fa145869cf5dd8bee7680b1c8fada42
ToppCell368C-Endothelial_cells-Endothelial-D-|368C / Donor, Lineage, Cell class and subclass (all cells)

FLT1 MMRN2 PNCK PALMD

1.40e-04175674ca0d3e3a0a271cccdd3881b055fecb626712478d
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.43e-041766745386386619cf173939d3c117b20e6f27ab397993
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN4 FLT1 MMRN2 GRAMD1C

1.43e-0417667427e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCellfacs-Heart-RV-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD

1.43e-04176674fb3d03f64592e1df1d9785d9f2e70938d7ff9ce8
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT1 MMRN2 MCM6 PALMD

1.43e-04176674269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCellfacs-Heart-RV-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD

1.43e-041766743270a36fc91a5583646ffeb70bfcbc5af7292aac
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.43e-04176674820edade963768e4bfd86b554da4cd7100567ac8
ToppCellfacs-Heart-RV-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD

1.43e-0417667499410c121f55adbc7fcc013c8fa8905a45dba76b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP6 FLT1 MMRN2 PALMD

1.43e-0417667427e6b3ae41068d6cfdda3d46da7df2a27567140e
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP6 FLT1 MMRN2 PALMD

1.43e-04176674d6a5470af9592f34a741265f2ea9651c05c3add3
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP6 FLT1 MMRN2 PALMD

1.46e-041776746f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCellfacs-Lung-Endomucin|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.49e-04178674363e523233b1800a4c8e14c7b1a7814b8da29ccd
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.49e-04178674ba2f0585626988b511046630bc16be5c5fec3fb2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MMRN2 PALMD EMP2

1.49e-041786745f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCellfacs-Heart-RV-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD

1.53e-041796746aa211670e5d6e013d0980967aa0a4f8f2905efe
ToppCellfacs-GAT-Fat-18m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.53e-04179674d56fa2a0b119d51a8d41b00fbbd7dfddefeb279c
ToppCellfacs-GAT-Fat-18m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.53e-04179674e0542694fa79d67f67be6f85b4fa6d18f7523253
ToppCellfacs-Heart-RV-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD

1.53e-04179674cf4d3828a3ce97932c68d06f5c65a070fc6d832c
ToppCellfacs-Heart-RV-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MCC MMRN2 PALMD

1.53e-04179674f9bc76ff25f88ee44c72499a0df9dc16f519c4cb
ToppCellfacs-GAT-Fat-18m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.53e-0417967483343b68977969c7978acd930a66fc7c44df6a15
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLT1 MCC MMRN2 PALMD

1.53e-041796742a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellfacs-Heart-RA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.56e-04180674174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCellEndothelial-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

FLT1 GRK5 MMRN2 PALMD

1.56e-041806744c3376169770ee9f9283daae44c17f35e46bfd19
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP6 FLT1 MMRN2 PALMD

1.59e-041816744d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCelldroplet-Heart-nan-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.59e-04181674859c40889ede2cbf374c4d2efbb72dc3bc6441f5
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Dpy19l1_(Neuron.Gad1Gad2.Synpr-Dpy19l1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH8 NUP62CL FREM1

1.61e-04706731d06fd0e20f4b3ea71a83c87736236f5c8d39f65
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2.Synpr-Dpy19l1_(Neuron.Gad1Gad2.Synpr-Dpy19l1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MYH8 NUP62CL FREM1

1.61e-0470673e446f52534a1e8291dbb0973c6bc5094a3ebc96b
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FLT1 MMRN2 PALMD EMP2

1.63e-04182674997d37ca2af661c92a56add888762724dfccc890
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLT1 MMRN2 PALMD CRACR2B

1.63e-04182674345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLT1 MMRN2 RNF213 PALMD

1.63e-041826747af3b2029b7f55b923d5a4b764d4292f4ea48599
ToppCellE18.5-samps-Endothelial|E18.5-samps / Age Group, Lineage, Cell class and subclass

FLT1 MMRN2 RNF213 PALMD

1.63e-04182674e2d799e6e7526176a6fe6515b8fbe4d83d3a3ea1
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.63e-04182674f4a5f1c3a04c0566eb96607dab7a0d9a5ebc3fd1
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP6 FLT1 MMRN2 PALMD

1.66e-041836743427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCellP15-Endothelial|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLT1 MMRN2 PALMD CRACR2B

1.66e-04183674ef82ce4658a775ee2ef0e564d2d1042898a1bd75
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ENPP6 FLT1 MMRN2 PALMD

1.66e-04183674fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD

1.70e-04184674fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCellP28-Endothelial|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLT1 MMRN2 PALMD CRACR2B

1.70e-04184674b056411f499866097f4322999cfd1e57a3927b78
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 FLT1 MMRN2 PALMD

1.70e-04184674ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 MCC MMRN2 PALMD

1.70e-04184674842473fa415575441b595073a994b6d621169776
ToppCell(4)_Endothelial_cells-(40)_EC-arterial|World / Cell class and subclass of bone marrow stroma cells in homeostatis

FLT1 MMRN2 PALMD CRACR2B

1.70e-041846747e1a2971321ddcfa00d78d3e3ba7960e532f9392
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD

1.70e-041846741d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

ENPP6 FLT1 MMRN2 PALMD

1.70e-04184674b4c561924c508536fd2112e91e32176b95fdf63a
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 PALMD

1.70e-0418467476caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 FLT1 MMRN2 PALMD

1.70e-041846741fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ENPP6 FLT1 MMRN2 PALMD

1.70e-041846742467207aaea307873ab286f89cfc7668a227a694
ToppCellE12.5-Endothelial-capillary_endothelial_cell|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLT1 MMRN2 PALMD CRACR2B

1.73e-04185674e005d3c01a908157f780bbc1d53dd2ed814a39d2
ToppCellfacs-Pancreas-Endocrine-24m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP6 FLT1 MMRN2 EMP2

1.73e-041856747f9121bbff3471982aa8706a599922c2d28e6e9b
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MMRN2 PALMD CRACR2B

1.73e-04185674c3105978d971da7d0fad1a717ee29afee5ed6357
DrugFludrocortisone acetate [514-36-3]; Down 200; 9.4uM; PC3; HT_HG-U133A

TSNAXIP1 MIA2 GRK5 SPTB MMRN2 RBM5 PALMD

1.89e-061986773785_DN
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

CCDC88A NUP62CL PCLO GRK5 CATSPERB GRAMD1C

1.87e-051876765976_UP
DrugSanguinarine [2447-54-3]; Down 200; 12uM; MCF7; HT_HG-U133A

CEP104 SF3B3 AGL POLG PCLO RBM5

2.10e-051916764168_DN
Drug(+) -Levobunolol hydrochloride [47141-41-3]; Down 200; 12.2uM; PC3; HT_HG-U133A

CCDC88A PSME4 NUP62CL POLG MCC GRAMD1C

2.36e-051956766635_DN
DrugBetonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A

FLT1 INA NUP62CL GRK5 SPTB PALMD

2.43e-051966763745_UP
DrugAmbroxol hydrochloride [23828-92-4]; Up 200; 9.6uM; HL60; HG-U133A

SMARCA5 CCDC88A POLG SPTB MCC MFN1

2.65e-051996761623_UP
Diseasearthrogryposis multiplex congenita (is_implicated_in)

MYH8 VPS33B

2.86e-054652DOID:0080954 (is_implicated_in)
Diseasespinocerebellar ataxia type 5 (implicated_via_orthology)

SPTBN4 SPTB

2.86e-054652DOID:0050882 (implicated_via_orthology)
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

ADGRV1 STX1B

1.70e-049652C3502809
Diseasecerebral cavernous malformation (implicated_via_orthology)

RNF213 CDC42BPB

2.59e-0411652DOID:0060669 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
EARFYLVDSEVLTHD

GRAMD1C

411

Q8IYS0
REHFEVDYVTVTFER

CATSPERB

306

Q9H7T0
TRSTEEEEERLEREH

CARNMT1

51

Q8N4J0
STEAIRASREEIHEY

INA

301

Q16352
ADITVLREREVDYDS

GTPBP2

136

Q9BX10
ERTVIIDEDRISRYE

ADGRV1

401

Q8WXG9
IDEDRISRYEEITVV

ADGRV1

406

Q8WXG9
SDHEQRELYEAARVI

CAMTA2

1041

O94983
EEEIVDLRERHYDSI

AP1AR

66

Q63HQ0
ISSLYHEETIREEDK

ACBD6

146

Q9BR61
ENSEFEEIHEVIARY

CCDC42

161

Q96M95
AAEDKRHYSVEERED

MFN1

361

Q8IWA4
RHYSVEEREDQIDRL

MFN1

366

Q8IWA4
EIDHDRRVVYTETLA

ANKRD13B

196

Q86YJ7
VEREERAEESIEDIY

PALMD

126

Q9NP74
VVAHEVYSDEALRVT

CASK

446

O14936
HSRIEESIDRVYSLD

MCM6

556

Q14566
RIHYQADVRLEATEE

MAPK8IP1

266

Q9UQF2
TRHVDEIKELYSESD

MMRN2

406

Q9H8L6
RTEFTVEVYETHARI

LENG8

616

Q96PV6
ESEVSRYKERLHDIE

CCDC88A

326

Q3V6T2
HERRVKELTYQTEED

MYH8

1846

P13535
VTDYTREIQEIIAHE

PCLO

2146

Q9Y6V0
IKVYREDDTATEETH

PLRG1

486

O43660
VLRSESEEKVVTYDH

INPP5A

361

Q14642
SHSERRHDEVELEVY

FREM1

376

Q5H8C1
ISIHDEVRYLVREED

POLG

1131

P54098
YEHELALRQTVEADV

KRT16

206

P08779
FYEEELVRREASHVL

CDC42BPB

696

Q9Y5S2
ELVEVEDDVYLRHSS

HMHB1

21

O97980
DYRHDISDERESKTI

RBM5

86

P52756
TDYQVEETSREREER

HTATSF1

351

O43719
KHTEDISSVYEIRER

PNCK

6

Q6P2M8
IAASIYTDRREDIHD

EMP2

111

P54851
SALEHRVYEVRETAV

CEP104

616

O60308
EHEDVQERTTLRYEE

MCC

66

P23508
EHEREVRALYEETEQ

CRACR2B

206

Q8N4Y2
RADLAAIYHERIDVE

ENPP6

181

Q6UWR7
EVDRRVLETEEVYSH

GRK5

396

P34947
IDEAHERSVYTDILI

DHX37

371

Q8IY37
DEKISHATEELETYR

MIA2

1026

Q96PC5
IDNISSREEIDHAEY

MRPS27

76

Q92552
IHRIDRTASYEEEVE

UTP20

31

O75691
RVDLLEQVAREHEEY

SYNE3

211

Q6ZMZ3
TAEETVQEEEREIYR

SENP1

181

Q9P0U3
EEDEEALHYLTRVEV

SET

111

Q01105
ALHYLTRVEVTEFED

SET

116

Q01105
RVHTVEDYQAIVDAE

CCT7

256

Q99832
GEEYTRDEDHIALII

SRPK1

556

Q96SB4
YSLATEEIERDLHRS

TBC1D9B

546

Q66K14
TLTDRELEEYRREVE

ADD1

566

P35611
TELHVISYEVERDLT

RNF213

4916

Q63HN8
HPTITDEERRYIEES

SLC17A6

271

Q9P2U8
VEDVRTVLEHYALED

TIMM50

291

Q3ZCQ8
EDQEHTYRVVRFEVI

TM9SF4

196

Q92544
EAATSLYDRVDEEVH

PLEKHG4B

431

Q96PX9
ETDHILESLYRDIRD

STX11

36

O75558
VEHSVDYVERAVSDT

STX1B

236

P61266
HEAIEADIAAYEERV

SPTBN4

471

Q9H254
AIETDTAAYEERVRA

SPTB

466

P11277
EYDLSRENHREVIAT

PSME4

856

Q14997
TVRRHIEDEFDAYII

SF3B3

461

Q15393
HARVDKVDEERYDIE

TNNI3

101

P19429
YRHRRTEQEEDEELL

SMARCA5

141

O60264
DTLRASYEEVRKEHE

TSNAXIP1

276

Q2TAA8
LFIERVTEEDEGVYH

FLT1

716

P17948
IRESTSYIEEHIDRQ

VPS33B

376

Q9H267
EESSLETRRYREVVD

ZMAT1

246

Q5H9K5
YVDQVDEDIVAVTRH

AGL

721

P35573
YLQDADEEHVEISTR

NUP62CL

166

Q9H1M0