Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

TRAP1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

8.22e-11401198GO:0140662
GeneOntologyMolecularFunctionprotein folding chaperone

TRAP1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

1.22e-08731198GO:0044183
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

CFTR GPN1 ATL3 RNF213 TRIM23 ATL1 TRAP1 IRGC GTPBP3 RAB37 HSPA1A HSPA1B HSPA1L HSPA2 RAB26 HSPA6 HSPA7 HSPA8

7.65e-0777511918GO:0017111
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC25A21 SLC2A9 SLC24A3 SLC25A26 SLC12A5 SLCO1B7 SLC6A3 SLC8B1 SLC24A4 SLC16A4 SLC25A1

1.61e-0629611911GO:0015291
GeneOntologyMolecularFunctionpyrophosphatase activity

CFTR GPN1 ATL3 RNF213 TRIM23 ATL1 TRAP1 IRGC GTPBP3 RAB37 HSPA1A HSPA1B HSPA1L HSPA2 RAB26 HSPA6 HSPA7 HSPA8

2.36e-0683911918GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

CFTR GPN1 ATL3 RNF213 TRIM23 ATL1 TRAP1 IRGC GTPBP3 RAB37 HSPA1A HSPA1B HSPA1L HSPA2 RAB26 HSPA6 HSPA7 HSPA8

2.40e-0684011918GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

CFTR GPN1 ATL3 RNF213 TRIM23 ATL1 TRAP1 IRGC GTPBP3 RAB37 HSPA1A HSPA1B HSPA1L HSPA2 RAB26 HSPA6 HSPA7 HSPA8

2.40e-0684011918GO:0016818
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B HSPA8

4.07e-0661193GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B HSPA8

4.07e-0661193GO:0055131
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC25A21 SLC2A9 CFTR SLC24A3 ATP6V1F SLC25A26 SLC12A5 SLCO1B7 SLC6A3 SLC8B1 SLC24A4 SLC16A4 SLC25A1

5.48e-0647711913GO:0022804
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1A SLC25A21 SLC2A9 CFTR SLC24A3 ATP6V1F SLC25A26 PKD1L2 SLC12A5 ITPR2 SLCO1B7 SLC6A3 SEC61A2 SLC8B1 SLC24A4 SLC16A4 SLC25A1 SCN2B KCNK10 NIPA2 GRIN3A

5.97e-06118011921GO:0022857
GeneOntologyMolecularFunctionheat shock protein binding

KSR1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

6.04e-061631198GO:0031072
GeneOntologyMolecularFunctionunfolded protein binding

TRAP1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.05e-051261197GO:0051082
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A SLC24A3 PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A

2.20e-0546511912GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1A SLC2A9 SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A

2.23e-0562711914GO:0022890
GeneOntologyMolecularFunctiontransporter activity

CACNA1A SLC25A21 SLC2A9 CFTR SLC24A3 ATP6V1F SLC25A26 PKD1L2 SLC12A5 ITPR2 SLCO1B7 SLC6A3 SEC61A2 SLC8B1 SLC24A4 SLC16A4 SLC25A1 SCN2B KCNK10 NIPA2 GRIN3A

2.27e-05128911921GO:0005215
GeneOntologyMolecularFunctioncalcium:sodium antiporter activity

SLC24A3 SLC8B1 SLC24A4

2.40e-05101193GO:0005432
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A SLC24A3 PKD1L2 ITPR2 SLC8B1 SLC24A4 GRIN3A

3.40e-051511197GO:0015085
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A SLC2A9 SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A

4.17e-0566411914GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1A SLC2A9 CFTR SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A

4.50e-0575811915GO:0015318
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity

SLC24A3 SLC8B1 SLC24A4

5.65e-05131193GO:0015368
GeneOntologyMolecularFunctionATP hydrolysis activity

CFTR GPN1 RNF213 TRAP1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

6.68e-0544111911GO:0016887
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A SLC2A9 CFTR SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A

7.49e-0579311915GO:0015075
GeneOntologyMolecularFunctionATP-dependent activity

CFTR GPN1 RNF213 ATP6V1F TRAP1 MYO15A HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

7.64e-0561411913GO:0140657
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

HSPA1A HSPA1B HSPA8

8.91e-05151193GO:0140776
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

1.05e-0431192GO:0031249
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A SLC24A3 PKD1L2 ITPR2 SLC24A4 GRIN3A

1.24e-041291196GO:0005262
GeneOntologyMolecularFunctionantiporter activity

SLC25A21 SLC24A3 SLC25A26 SLC8B1 SLC24A4 SLC25A1

1.79e-041381196GO:0015297
GeneOntologyMolecularFunctioncadherin binding

FLNA FLNB PTPN11 CDH22 HSPA1A CDH9 HSPA8 CDH11 CDH18

1.98e-043391199GO:0045296
GeneOntologyMolecularFunctionsymporter activity

SLC2A9 SLC24A3 SLC12A5 SLC6A3 SLC24A4 SLC16A4

2.81e-041501196GO:0015293
GeneOntologyMolecularFunctiondeath receptor agonist activity

HSPA1A HSPA1B

3.48e-0451192GO:0038177
GeneOntologyMolecularFunctioncalcium, potassium:sodium antiporter activity

SLC24A3 SLC24A4

3.48e-0451192GO:0008273
GeneOntologyMolecularFunctioncell adhesion molecule binding

FLNA FLNB ADAM8 PTPN11 CDH22 TENM1 HSPA1A CDH9 HSPA8 CDH11 CDH18

9.13e-0459911911GO:0050839
GeneOntologyMolecularFunctionGTPase activity

GPN1 ATL3 TRIM23 ATL1 IRGC GTPBP3 RAB37 RAB26

1.01e-033411198GO:0003924
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1A SLC24A3 PKD1L2 ITPR2 SLC24A4 SCN2B KCNK10 GRIN3A

1.05e-033431198GO:0005261
GeneOntologyMolecularFunctionchannel activity

CACNA1A CFTR SLC24A3 PKD1L2 SLC12A5 ITPR2 SLC24A4 SCN2B KCNK10 GRIN3A

1.19e-0352511910GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A CFTR SLC24A3 PKD1L2 SLC12A5 ITPR2 SLC24A4 SCN2B KCNK10 GRIN3A

1.21e-0352611910GO:0022803
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC25A21 SLC25A26 SLCO1B7 SLC16A4 SLC25A1 GRIN3A

1.52e-032071196GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC25A21 SLC25A26 SLCO1B7 SLC16A4 SLC25A1 GRIN3A

1.55e-032081196GO:0005342
GeneOntologyMolecularFunctiondisordered domain specific binding

HSPA1A HSPA1B HSPA2

1.61e-03391193GO:0097718
GeneOntologyMolecularFunctioncalcium ion binding

GPD2 DCHS2 MATN1 ADGRV1 PKD1L2 ADAM8 ITPR2 CDH22 CDH9 CDH11 ALOX15B CDH18

1.72e-0374911912GO:0005509
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A CFTR SLC24A3 PKD1L2 ITPR2 SLC24A4 SCN2B KCNK10 GRIN3A

1.72e-034591199GO:0005216
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC25A21 CFTR SLC25A26 SLCO1B7 SLC16A4 SLC25A1 GRIN3A

1.89e-032931197GO:0008514
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC24A3 SLC8B1 SLC24A4

2.14e-03431193GO:0140828
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC2A9 SLC24A3 ATP6V1F SLC12A5 SLC6A3 SLC8B1 SLC24A4

2.19e-033011197GO:0022853
GeneOntologyMolecularFunctionactin filament binding

FLNA FLNB FLNC ACTR3C CORO1C MYO15A

2.41e-032271196GO:0051015
GeneOntologyMolecularFunctionGTP binding

GPN1 ATL3 TRIM23 ATL1 IRGC GTPBP3 RAB37 RAB26

2.62e-033971198GO:0005525
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

SLC24A3 SLC12A5 SLC24A4 SCN2B KCNK10

3.27e-031671195GO:0015079
GeneOntologyMolecularFunctioninsulin receptor substrate binding

JAK2 PTPN11

3.52e-03151192GO:0043560
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC24A3 SLC6A3 SLC8B1 SLC24A4 SCN2B

3.62e-031711195GO:0015081
GeneOntologyMolecularFunctionguanyl ribonucleotide binding

GPN1 ATL3 TRIM23 ATL1 IRGC GTPBP3 RAB37 RAB26

4.81e-034391198GO:0032561
GeneOntologyMolecularFunctionguanyl nucleotide binding

GPN1 ATL3 TRIM23 ATL1 IRGC GTPBP3 RAB37 RAB26

4.81e-034391198GO:0019001
GeneOntologyMolecularFunctionmisfolded protein binding

HSPA1A HSPA1B

5.06e-03181192GO:0051787
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC24A3 SLC24A4

5.64e-03191192GO:0022821
GeneOntologyMolecularFunctionbeta-catenin binding

CDH22 CDH9 CDH11 CDH18

5.79e-031201194GO:0008013
GeneOntologyMolecularFunctionNADP binding

DPYD NDOR1 ASPDH

6.04e-03621193GO:0050661
GeneOntologyMolecularFunctionpeptide hormone receptor binding

JAK2 PTPN11

6.87e-03211192GO:0051428
GeneOntologyMolecularFunctiondeath receptor activity

HSPA1A HSPA1B

6.87e-03211192GO:0005035
GeneOntologyMolecularFunctionimmunoglobulin receptor binding

FLNA ADAM8

6.87e-03211192GO:0034987
GeneOntologyBiologicalProcessprotein refolding

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

3.44e-10301207GO:0042026
GeneOntologyBiologicalProcesschaperone cofactor-dependent protein refolding

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

1.11e-09351207GO:0051085
GeneOntologyBiologicalProcess'de novo' post-translational protein folding

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

3.61e-09411207GO:0051084
GeneOntologyBiologicalProcess'de novo' protein folding

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

8.39e-09461207GO:0006458
GeneOntologyBiologicalProcesschaperone-mediated protein folding

TRAP1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

2.12e-08801208GO:0061077
GeneOntologyBiologicalProcesscellular heat acclimation

HSPA1A HSPA1B HSPA6

3.79e-0661203GO:0070370
GeneOntologyBiologicalProcessheat acclimation

HSPA1A HSPA1B HSPA6

6.61e-0671203GO:0010286
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1A FLNA SLC2A9 CFTR SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A HSPA2

2.45e-0592212017GO:0098662
GeneOntologyBiologicalProcessresponse to temperature stimulus

CES1 SLC12A5 SCN2B HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

2.99e-052081208GO:0009266
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1A FLNA SLC2A9 CFTR SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A HSPA2

3.21e-0594212017GO:0098655
GeneOntologyBiologicalProcessnegative regulation of inclusion body assembly

HSPA1A HSPA1B HSPA2

4.07e-05121203GO:0090084
GeneOntologyBiologicalProcessresponse to heat

SCN2B HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

7.62e-051211206GO:0009408
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1A FLNA SLC2A9 CFTR SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A HSPA2

8.29e-05101712017GO:0098660
GeneOntologyBiologicalProcessprotein folding

TRAP1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

9.73e-052461208GO:0006457
GeneOntologyBiologicalProcessresponse to abiotic stimulus

CES1 ADGRV1 PKD1L2 ADAM8 GRM8 AKAP12 SLC12A5 ITPR2 PTPN11 SERPINB13 SLC24A4 CYP2R1 SCN2B TSPYL5 MYO15A HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.10e-04136112020GO:0009628
GeneOntologyBiologicalProcesscell-cell adhesion mediated by cadherin

CDH22 CDH9 CDH11 CDH18

2.04e-04501204GO:0044331
GeneOntologyBiologicalProcessregulation of inclusion body assembly

HSPA1A HSPA1B HSPA2

2.37e-04211203GO:0090083
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1A FLNA SLC2A9 CFTR SLC24A3 ATP6V1F PKD1L2 SLC12A5 ITPR2 SLC6A3 SLC8B1 SLC24A4 SCN2B KCNK10 NIPA2 GRIN3A HSPA2

2.49e-04111512017GO:0034220
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

CDH22 CDH9 CDH11 CDH18

2.56e-04531204GO:0016339
GeneOntologyCellularComponentCOP9 signalosome

DCAF1 HSPA1A HSPA1B HSPA1L HSPA6 HSPA7

7.88e-08381216GO:0008180
GeneOntologyCellularComponentblood microparticle

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

2.09e-051441217GO:0072562
GeneOntologyCellularComponentcatenin complex

CDH22 CDH9 CDH11 CDH18

3.39e-05321214GO:0016342
GeneOntologyCellularComponentanchoring junction

FLNA FLNB FLNC DCHS2 CORO1C MPDZ AKAP12 JAK2 CDH22 HSPA1A HSPA1B CDH9 HSPA8 CDH11 ALOX15B CDH18 PDZD2

4.71e-0597612117GO:0070161
GeneOntologyCellularComponentcell body

CACNA1A FLNA FLNB COPA CYP17A1 CFTR RAPGEF4 GRM8 AKAP12 SLC12A5 SORT1 SLC6A3 GRIN3A HSPA1B HSPA1L HSPA8

9.16e-0592912116GO:0044297
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1A FLNA CORO1C MPDZ ADAM8 SLC6A3 JAK2 CDH22 SCN2B GRIN3A HSPA2 CDH9 CDH11 CDH18

1.81e-0478512114GO:0098797
GeneOntologyCellularComponentfocal adhesion

FLNA FLNB FLNC CORO1C AKAP12 JAK2 HSPA1A HSPA1B HSPA8 ALOX15B

2.07e-0443112110GO:0005925
GeneOntologyCellularComponentcell-substrate junction

FLNA FLNB FLNC CORO1C AKAP12 JAK2 HSPA1A HSPA1B HSPA8 ALOX15B

2.57e-0444312110GO:0030055
GeneOntologyCellularComponentcluster of actin-based cell projections

FLNA FLNB AMN RAPGEF4 ADGRV1 PKHD1L1 MYO15A

3.23e-042231217GO:0098862
GeneOntologyCellularComponentendoplasmic reticulum tubular network membrane

ATL3 ATL1

3.29e-0451212GO:0098826
GeneOntologyCellularComponentneuronal cell body

CACNA1A FLNA FLNB COPA CYP17A1 CFTR RAPGEF4 GRM8 AKAP12 SLC12A5 SORT1 SLC6A3 GRIN3A HSPA8

3.40e-0483512114GO:0043025
GeneOntologyCellularComponentmembrane protein complex

CACNA1A FLNA COPA CORO1C CFTR MPDZ ATP6V1F ADAM8 DDOST SLC6A3 JAK2 SEC61A2 CDH22 SCN2B KCNK10 GRIN3A HSPA2 CDH9 CDH11 CDH18

3.69e-04149812120GO:0098796
GeneOntologyCellularComponentextrinsic component of plasma membrane

JAK2 CDH22 CDH9 CDH11 CDH18

1.22e-031371215GO:0019897
GeneOntologyCellularComponentflotillin complex

CORO1C SLC6A3

1.45e-03101212GO:0016600
GeneOntologyCellularComponentzona pellucida receptor complex

HSPA1B HSPA1L

1.77e-03111212GO:0002199
GeneOntologyCellularComponentsomatodendritic compartment

CACNA1A FLNA FLNB COPA CYP17A1 CFTR RAPGEF4 MPDZ GRM8 AKAP12 SLC12A5 SORT1 SLC6A3 GRIN3A CDH9 HSPA8

1.92e-03122812116GO:0036477
DomainHSP70

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

4.38e-12161217PF00012
DomainHSP70_2

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

7.41e-12171217PS00329
DomainHSP70_1

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

7.41e-12171217PS00297
DomainHSP70_3

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

7.41e-12171217PS01036
DomainHsp_70_fam

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

1.21e-11181217IPR013126
Domain-

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

8.02e-091212152.60.34.10
DomainHSP70_peptide-bd

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

8.02e-09121215IPR029047
Domain-

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

1.30e-081312151.20.1270.10
DomainHeat_shock_70_CS

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

1.30e-08131215IPR018181
DomainHSP70_C

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

1.30e-08131215IPR029048
DomainCadherin_C

CDH22 CDH9 CDH11 CDH18

1.91e-05251214PF01049
DomainCadherin_cytoplasmic-dom

CDH22 CDH9 CDH11 CDH18

1.91e-05251214IPR000233
DomainNaCa_Exmemb

SLC24A3 SLC8B1 SLC24A4

2.17e-0591213IPR004837
DomainNa_Ca_ex

SLC24A3 SLC8B1 SLC24A4

2.17e-0591213PF01699
DomainIG_FLMN

FLNA FLNB FLNC

3.08e-05101213SM00557
DomainCatenin_binding_dom

CDH22 CDH9 CDH11 CDH18

3.51e-05291214IPR027397
Domain-

CDH22 CDH9 CDH11 CDH18

3.51e-052912144.10.900.10
DomainGM2_synthase

B4GALNT1 B4GALNT2

4.16e-0521212IPR011143
DomainFilamin

FLNA FLNB FLNC

4.21e-05111213PF00630
DomainFILAMIN_REPEAT

FLNA FLNB FLNC

4.21e-05111213PS50194
DomainFilamin/ABP280_rpt

FLNA FLNB FLNC

4.21e-05111213IPR001298
DomainFilamin/ABP280_repeat-like

FLNA FLNB FLNC

4.21e-05111213IPR017868
DomainPeptidase_S1C

HTRA1 HTRA4

2.48e-0441212IPR001940
Domain-

SLC25A46 SLC25A21 SLC25A26 SLC25A1

3.84e-045312141.50.40.10
DomainMito_carr

SLC25A46 SLC25A21 SLC25A26 SLC25A1

3.84e-04531214PF00153
DomainSOLCAR

SLC25A46 SLC25A21 SLC25A26 SLC25A1

3.84e-04531214PS50920
DomainMitochondrial_sb/sol_carrier

SLC25A46 SLC25A21 SLC25A26 SLC25A1

3.84e-04531214IPR018108
DomainMt_carrier_dom

SLC25A46 SLC25A21 SLC25A26 SLC25A1

3.84e-04531214IPR023395
DomainK/Na/Ca-exchanger

SLC24A3 SLC24A4

4.11e-0451212IPR004481
DomainACTININ_2

FLNA FLNB FLNC

4.27e-04231213PS00020
DomainACTININ_1

FLNA FLNB FLNC

4.27e-04231213PS00019
DomainActinin_actin-bd_CS

FLNA FLNB FLNC

4.27e-04231213IPR001589
DomainIg_E-set

FLNA FLNB FLNC CD109 PKHD1L1

5.79e-041041215IPR014756
DomainCadherin_CS

DCHS2 CDH22 CDH9 CDH11 CDH18

7.17e-041091215IPR020894
DomainCADHERIN_1

DCHS2 CDH22 CDH9 CDH11 CDH18

8.44e-041131215PS00232
DomainCadherin

DCHS2 CDH22 CDH9 CDH11 CDH18

8.44e-041131215PF00028
DomainCADHERIN_2

DCHS2 CDH22 CDH9 CDH11 CDH18

8.79e-041141215PS50268
Domain-

DCHS2 CDH22 CDH9 CDH11 CDH18

8.79e-0411412152.60.40.60
DomainCA

DCHS2 CDH22 CDH9 CDH11 CDH18

9.14e-041151215SM00112
DomainCadherin-like

DCHS2 CDH22 CDH9 CDH11 CDH18

9.50e-041161215IPR015919
DomainCadherin

DCHS2 CDH22 CDH9 CDH11 CDH18

1.03e-031181215IPR002126
DomainKazal_2

HTRA1 HTRA4 SLCO1B7

1.62e-03361213PF07648
DomainGBP_C

ATL3 ATL1

1.81e-03101212PF02841
DomainG_GB1_RHD3_dom

ATL3 ATL1

2.20e-03111212IPR030386
DomainGuanylate-bd_N

ATL3 ATL1

2.20e-03111212IPR015894
DomainGuanylate-bd_C

ATL3 ATL1

2.20e-03111212IPR003191
DomainGBP

ATL3 ATL1

2.20e-03111212PF02263
DomainG_GB1_RHD3

ATL3 ATL1

2.20e-03111212PS51715
DomainFAD-dep_OxRdtase

GPD2 L2HGDH

2.63e-03121212IPR006076
DomainDAO

GPD2 L2HGDH

2.63e-03121212PF01266
Domain-

CFTR GPN1 ATL3 RNF213 TEP1 TRIM23 ATL1 IRGC GTPBP3 MYO15A RAB37 RAB26

3.31e-03746121123.40.50.300
DomainKAZAL_2

HTRA1 HTRA4 SLCO1B7

4.16e-03501213PS51465
DomainKazal_dom

HTRA1 HTRA4 SLCO1B7

4.40e-03511213IPR002350
Domain-

GPD2 DPYD L2HGDH

5.73e-035612133.50.50.60
DomainLH2

PKD1L2 ALOX15B

5.95e-03181212SM00308
Domain-

DCAF1 COPA NBEAL1 CORO1C GEMIN5 TEP1 SORT1

6.01e-0333312172.130.10.10
DomainFAD/NAD-binding_dom

GPD2 DPYD L2HGDH

6.02e-03571213IPR023753
DomainWD40/YVTN_repeat-like_dom

DCAF1 COPA NBEAL1 CORO1C GEMIN5 TEP1 SORT1

6.20e-033351217IPR015943
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

1.17e-0813905MM14952
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.92e-0828906M27254
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.34e-0738906M27255
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

2.91e-0723905MM14953
PathwayKEGG_MAPK_SIGNALING_PATHWAY

CACNA1A FLNA FLNB FLNC DUSP14 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.01e-062679011M10792
PathwayREACTOME_INTERFERON_SIGNALING

FLNB JAK2 PTPN11 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

2.71e-06138908MM15635
PathwayWP_MAPK_SIGNALING

CACNA1A FLNA FLNB FLNC HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

3.67e-062469010M39597
PathwayWP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

5.87e-0671906M39690
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.36e-0582906M27250
PathwayKEGG_SPLICEOSOME

RBM22 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.64e-05127907M2044
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

1.95e-0552905MM14949
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

2.04e-0588906M16004
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A9 SLC24A3 SLC25A26 SLC12A5 SLCO1B7 SLC6A3 SLC8B1 SLC24A4 SLC25A1

2.06e-05238909MM15076
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

FLNB HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

2.97e-0594906MM14515
PathwayREACTOME_HSP90_CHAPERONE_CYCLE_FOR_STEROID_HORMONE_RECEPTORS_SHR_IN_THE_PRESENCE_OF_LIGAND

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

3.06e-0557905M27251
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC24A3 SLC8B1 SLC24A4

4.00e-0511903M27336
PathwayWP_NPHP1_DELETION_SYNDROME

FLNA FLNB FLNC

4.00e-0511903M48099
PathwayREACTOME_HSF1_ACTIVATION

HSPA1A HSPA1B HSPA1L HSPA6

4.28e-0531904M27252
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

4.46e-05101906M27253
PathwayREACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES

FLNA FLNB HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

5.00e-05151907M550
PathwayREACTOME_INTERFERON_SIGNALING

FLNA FLNB JAK2 PTPN11 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

6.03e-05273909M983
PathwayREACTOME_PKR_MEDIATED_SIGNALING

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

6.24e-0566905MM17074
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC24A3 SLC25A26 SLC12A5 SLC8B1 SLC24A4 SLC25A1

6.50e-05108906M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC24A3 SLC25A26 SLC12A5 SLC8B1 SLC24A4 SLC25A1

6.84e-05109906MM15074
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC24A3 SLC8B1 SLC24A4

6.87e-0513903MM15078
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

FLNA FLNC CDH9 CDH11 CDH18

1.01e-0473905MM15126
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

1.01e-0473905MM14948
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

DCAF1 CDH22 PRKAR1B CDH9 CDH11 CDH18

1.22e-04121906M39823
PathwayREACTOME_PKR_MEDIATED_SIGNALING

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

1.23e-0476905M48037
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A9 SLC24A3 SLC25A26 SLC12A5 SLC6A3 SLC8B1 SLC24A4 SLC25A1

1.88e-04249908M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

AMN SLC2A9 CFTR PSMB9 SLC24A3 ATP6V1F SLC25A26 SLC12A5 SLC6A3 SLC8B1 SLC24A4 SLC25A1 PRKAR1B NIPA2

2.22e-047369014M27287
PathwayWP_MEASLES_VIRUS_INFECTION

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

2.31e-04136906M42547
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

3.01e-0492905MM14951
PathwayREACTOME_INTERLEUKIN_6_FAMILY_SIGNALING

IL31RA JAK2 PTPN11

3.55e-0422903MM15319
PathwayREACTOME_CELL_CELL_COMMUNICATION

FLNA FLNC CDH9 CDH11 CDH18

3.67e-0496905MM14592
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC2A9 CFTR SLC24A3 ATP6V1F SLC25A26 SLC12A5 SLCO1B7 SLC6A3 SLC8B1 SLC24A4 SLC25A1 PRKAR1B NIPA2

3.68e-046819013MM14985
PathwayWP_HIPPO_SIGNALING_REGULATION

CDH22 PRKAR1B CDH9 CDH11 CDH18

4.04e-0498905M39830
PathwayREACTOME_INTERLEUKIN_6_FAMILY_SIGNALING

IL31RA JAK2 PTPN11

4.62e-0424903M27604
PathwayREACTOME_CELL_CELL_COMMUNICATION

FLNA FLNC PTPN11 CDH9 CDH11 CDH18

4.67e-04155906M522
PathwayREACTOME_CELL_JUNCTION_ORGANIZATION

FLNA FLNC CDH9 CDH11 CDH18

9.06e-04117905M19248
PathwayWP_TYPE_II_INTERFERON_SIGNALING_IFNG

PSMB9 JAK2 PTPN11

9.94e-0431903MM15958
PathwayKEGG_ENDOCYTOSIS

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.05e-03181906M1519
PathwayWP_NONCLASSICAL_ROLE_OF_VITAMIN_D

REN CYP2R1

1.10e-038902M42566
PathwayREACTOME_MAPK1_ERK2_ACTIVATION

JAK2 PTPN11

1.10e-038902MM14507
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1A RAPGEF4 ITPR2 PRKAR1B

1.15e-0372904MM14631
PathwayREACTOME_MAPK3_ERK1_ACTIVATION

JAK2 PTPN11

1.41e-039902MM14474
PathwayREACTOME_INTERLEUKIN_6_SIGNALING

JAK2 PTPN11

1.41e-039902MM14470
PathwayREACTOME_MAPK1_ERK2_ACTIVATION

JAK2 PTPN11

1.41e-039902M26918
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

CACNA1A RAPGEF4 ITPR2 PRKAR1B

1.55e-0378904M1921
PathwayWP_TYPE_II_INTERFERON_SIGNALING

PSMB9 JAK2 PTPN11

1.67e-0337903M39363
PathwayREACTOME_MAPK3_ERK1_ACTIVATION

JAK2 PTPN11

1.75e-0310902M26896
PathwayBIOCARTA_CFTR_PATHWAY

CFTR PRKAR1B

1.75e-0310902MM1377
PathwayWP_NRF2_PATHWAY

SLC2A9 CES1 SLC6A3 ADH7 HSPA1A

2.07e-03141905M39454
PathwayREACTOME_ADHERENS_JUNCTIONS_INTERACTIONS

CDH9 CDH11 CDH18

2.10e-0340903MM15060
PathwayREACTOME_SIGNALING_BY_LEPTIN

JAK2 PTPN11

2.14e-0311902M27195
PathwayREACTOME_INTERLEUKIN_6_SIGNALING

JAK2 PTPN11

2.14e-0311902M1014
PathwayBIOCARTA_CFTR_PATHWAY

CFTR PRKAR1B

2.14e-0311902M12399
Pubmed

Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

5.84e-119121521763498
Pubmed

Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.17e-1010121511932435
Pubmed

gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.17e-1010121512832005
Pubmed

Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.17e-101012157906708
Pubmed

Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.17e-1010121523921388
Pubmed

Variations in HSP70 genes associated with noise-induced hearing loss in two independent populations.

HSPA1A HSPA1B HSPA1L HSPA2

1.39e-104121418813331
Pubmed

Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.

HSPA1A HSPA1B HSPA1L HSPA8

1.39e-104121418299791
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.50e-1023121621231916
Pubmed

HIV-1 viral protein R (Vpr) and its interactions with host cell.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

3.64e-1012121519275587
Pubmed

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

5.90e-1013121527477512
Pubmed

HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.

HSPA1A HSPA1B HSPA1L HSPA8

6.95e-105121417182002
Pubmed

Targeting the interaction of AIMP2-DX2 with HSP70 suppresses cancer development.

FLNA FLNB HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

8.01e-1054121731792442
Pubmed

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry.

DCAF1 HSPA1A HSPA1B HSPA1L HSPA6 HSPA7

1.32e-0932121618850735
Pubmed

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.37e-0915121510964507
Pubmed

Clathrin facilitates the morphogenesis of retrovirus particles.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.99e-0916121521738476
Pubmed

Genetic aspects of the hsp70 multigene family in vertebrates.

HSPA1A HSPA1B HSPA1L HSPA8

2.08e-09612147988674
Pubmed

Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.

FLNA FLNB FLNC COPA ACTR3C CORO1C DDOST HSPA1A HSPA8

5.07e-09159121934537242
Pubmed

Function and regulation of heat shock factor 2 during mouse embryogenesis.

HSPA1A HSPA1B HSPA2 HSPA8

9.65e-09812149122205
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

GPD2 FLNA FLNB FLNC WWOX COPA CORO1C GPN1 DUSP14 ATL3 GEMIN5 DPYSL4 RNF213 AKAP12 PTPN11 SERPINB13 SLC25A1 TSPYL5 HSPA1A HSPA1L HSPA8

1.04e-0813671212132687490
Pubmed

Chromosomal localization of five murine HSP70 gene family members: Hsp70-1, Hsp70-2, Hsp70-3, Hsc70t, and Grp78.

HSPA1A HSPA1B HSPA1L HSPA2

1.73e-08912148486356
Pubmed

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription.

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.89e-0824121510617616
Pubmed

Autophagic degradation of the inhibitory p53 isoform Δ133p53α as a regulatory mechanism for p53-mediated senescence.

FLNA CORO1C HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

2.60e-0888121725144556
Pubmed

Analysis of heat shock protein 70 gene polymorphisms Mexican patients with idiopathic pulmonary fibrosis.

HSPA1A HSPA1B HSPA1L

4.11e-083121326496868
Pubmed

Genetic polymorphisms of HSP70 in age-related cataract.

HSPA1A HSPA1B HSPA1L

4.11e-083121323666708
Pubmed

Stress-induced localization of HSPA6 (HSP70B') and HSPA1A (HSP70-1) proteins to centrioles in human neuronal cells.

HSPA1A HSPA1B HSPA6

4.11e-083121324061851
Pubmed

Interacting contribution of the five polymorphisms in three genes of Hsp70 family to essential hypertension in Uygur ethnicity.

HSPA1A HSPA1B HSPA1L

4.11e-083121319085089
Pubmed

Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies.

HSPA1A HSPA1B HSPA1L

4.11e-083121311779758
Pubmed

The impact of heat shock protein 70 gene variations on clinical presentation and outcome in schizophrenic inpatients.

HSPA1A HSPA1B HSPA1L

4.11e-083121319439993
Pubmed

Is preeclampsia associated with higher frequency of HSP70 gene polymorphisms?

HSPA1A HSPA1B HSPA1L

4.11e-083121316202503
Pubmed

Heat-shock protein-70 genes and response to antidepressants in major depression.

HSPA1A HSPA1B HSPA1L

4.11e-083121317428599
Pubmed

Polymorphisms of heat shock protein 70 gene (HSPA1A, HSPA1B and HSPA1L) and schizophrenia.

HSPA1A HSPA1B HSPA1L

4.11e-083121315963589
Pubmed

Heat shock protein 70 gene polymorphisms in sudden sensorineural hearing loss.

HSPA1A HSPA1B HSPA1L

4.11e-083121322922572
Pubmed

Heat shock protein 70 gene polymorphisms in Han nationality of China with chronic obstructive pulmonary diseases.

HSPA1A HSPA1B HSPA1L

4.11e-083121315165109
Pubmed

Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis.

HSPA1A HSPA1B HSPA8

4.11e-083121323352621
Pubmed

A prospective evaluation of the heat shock protein 70 gene polymorphisms and the risk of stroke.

HSPA1A HSPA1B HSPA1L

4.11e-083121312008944
Pubmed

Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes.

HSPA1A HSPA1B HSPA8

4.11e-083121315129916
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNA FLNB FLNC

4.11e-083121312393796
Pubmed

Association of hsp70-2 and hsp-hom gene polymorphisms with risk of acute high-altitude illness in a Chinese population.

HSPA1A HSPA1B HSPA1L

4.11e-083121316333988
Pubmed

Association of hsp70 polymorphisms with risk of noise-induced hearing loss in Chinese automobile workers.

HSPA1A HSPA1L HSPA2

4.11e-083121317009596
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNA FLNB FLNC

4.11e-083121311153914
Pubmed

Heat shock protein 70 gene polymorphisms are associated with paranoid schizophrenia in the Polish population.

HSPA1A HSPA1B HSPA1L

4.11e-083121323893339
Pubmed

Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity.

HSPA1A HSPA1B HSPA1L

4.11e-083121319840767
Pubmed

Differential expression of HSPA1 and HSPA2 proteins in human tissues; tissue microarray-based immunohistochemical study.

HSPA1A HSPA1B HSPA2

4.11e-083121321373891
Pubmed

Chromosomal location of human genes encoding major heat-shock protein HSP70.

HSPA1A HSPA1B HSPA1L

4.11e-08312133470951
Pubmed

HSPA1A, HSPA2, and HSPA8 Are Potential Molecular Biomarkers for Prognosis among HSP70 Family in Alzheimer's Disease.

HSPA1A HSPA2 HSPA8

4.11e-083121336246562
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNA FLNB FLNC

4.11e-083121311252955
Pubmed

Heat-shock protein gene polymorphisms and the risk of nephropathy in patients with Type 2 diabetes.

HSPA1A HSPA1B HSPA1L

4.11e-083121318518860
Pubmed

Genetic interaction of Hsp70 family genes polymorphisms with high-altitude pulmonary edema among Chinese railway constructors at altitudes exceeding 4000 meters.

HSPA1A HSPA1B HSPA1L

4.11e-083121319351530
Pubmed

Localization of a human heat-shock HSP 70 gene sequence to chromosome 6 and detection of two other loci by somatic-cell hybrid and restriction fragment length polymorphism analysis.

HSPA1A HSPA1B HSPA1L

4.11e-08312132880793
Pubmed

HLA complex-linked heat shock protein genes and childhood acute lymphoblastic leukemia susceptibility.

HSPA1A HSPA1B HSPA1L

4.11e-083121320012387
Pubmed

Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients.

HSPA1A HSPA1B HSPA1L

4.11e-083121336345598
Pubmed

Functional analysis of HSPA1A and HSPA8 in parturition.

HSPA1A HSPA1B HSPA8

4.11e-083121328025138
Pubmed

Structure and expression of the three MHC-linked HSP70 genes.

HSPA1A HSPA1B HSPA1L

4.11e-08312131700760
Pubmed

Heat shock protein 70 gene polymorphism in Japanese patients with multiple sclerosis.

HSPA1A HSPA1B HSPA1L

4.11e-083121311696222
Pubmed

The relationship between three heat shock protein 70 gene polymorphisms and susceptibility to lung cancer.

HSPA1A HSPA1B HSPA1L

4.11e-083121320704535
Pubmed

Anti-inflammatory heat shock protein 70 genes are positively associated with human survival.

HSPA1A HSPA1B HSPA1L

4.11e-083121320388090
Pubmed

Human major histocompatibility complex contains genes for the major heat shock protein HSP70.

HSPA1A HSPA1B HSPA1L

4.11e-08312132538825
Pubmed

Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease.

HSPA1A HSPA1B HSPA1L

4.11e-083121314605873
Pubmed

Genomic structure of the spermatid-specific hsp70 homolog gene located in the class III region of the major histocompatibility complex of mouse and man.

HSPA1A HSPA1B HSPA1L

4.11e-08312139685725
Pubmed

Effects of polymorphisms of heat shock protein 70 gene on ischemic stroke, and interaction with smoking in China.

HSPA1A HSPA1B HSPA1L

4.11e-083121317582394
Pubmed

Polymorphisms of heat shock protein 70 genes (HSPA1A, HSPA1B and HSPA1L) and susceptibility of noise-induced hearing loss in a Chinese population: A case-control study.

HSPA1A HSPA1B HSPA1L

4.11e-083121328182740
Pubmed

WWP2 is an E3 ubiquitin ligase for PTEN.

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

5.21e-0829121521532586
Pubmed

Protein partners in the life history of activated fibroblast growth factor receptors.

COPA DDOST PTPN11 HSPA1L HSPA2 HSPA6

6.06e-0859121618022941
Pubmed

Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy.

CDH22 CDH9 CDH11 CDH18

6.75e-0812121422102170
Pubmed

A proteomic investigation of ligand-dependent HSP90 complexes reveals CHORDC1 as a novel ADP-dependent HSP90-interacting protein.

HSPA1A HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

7.43e-0861121619875381
Pubmed

A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.

HSPA1A HSPA1B HSPA1L HSPA8

9.73e-0813121430792309
Pubmed

Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.

TRAP1 HSPA1A HSPA1L HSPA6 HSPA8

1.20e-0734121520391533
Pubmed

Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.

DCAF1 HSPA1A HSPA1B HSPA6 HSPA8

1.40e-0735121519287380
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

FLNA FLNB FLNC COPA TRAP1 HSPA1A HSPA1L HSPA6 HSPA8

1.48e-07235121930258100
Pubmed

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin.

FLNA FLNB FLNC

1.64e-074121311739414
Pubmed

Structural interaction and functional regulation of polycystin-2 by filamin.

FLNA FLNB FLNC

1.64e-074121322802962
Pubmed

[Effect of HSP70 gene polymorphism on genetic susceptibility of pneumoconiosis of coal worker].

HSPA1A HSPA1B HSPA1L

1.64e-074121320568452
Pubmed

Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.

HSPA1A HSPA1B HSPA8

1.64e-074121322956628
Pubmed

Upregulation of the constitutively expressed HSC70 by KLF4.

HSPA1A HSPA1B HSPA8

1.64e-074121318379898
Pubmed

Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus.

HSPA1A HSPA1B HSPA1L

1.64e-074121320498198
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

FLNA FLNB FLNC MRI1 COPA CORO1C PTPN11 HSPA1A HSPA1B HSPA1L

3.77e-073441211030333137
Pubmed

Nephrocystin-conserved domains involved in targeting to epithelial cell-cell junctions, interaction with filamins, and establishing cell polarity.

FLNA FLNB FLNC

4.09e-075121312006559
Pubmed

hTid-1, a human DnaJ protein, modulates the interferon signaling pathway.

JAK2 HSPA1A HSPA8

4.09e-075121311679576
Pubmed

A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.

HSPA1A HSPA1B HSPA8

4.09e-075121311584023
Pubmed

Filamin B deficiency in mice results in skeletal malformations and impaired microvascular development.

FLNA FLNB FLNC

4.09e-075121317360453
Pubmed

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

HSPA1A HSPA1B HSPA8

4.09e-075121316906134
Pubmed

A susceptibility gene for alveolar lung tumors in the mouse maps between Hsp70.3 and G7 within the H2 complex.

HSPA1A HSPA1B HSPA1L

4.09e-07512137806281
Pubmed

Small kinetochore associated protein (SKAP) promotes UV-induced cell apoptosis through negatively regulating pre-mRNA processing factor 19 (Prp19).

HSPA1A HSPA6 HSPA8

4.09e-075121324718257
Pubmed

Polymorphisms in TNF and HSP-70 show a significant association with gastric cancer and duodenal ulcer.

HSPA1A HSPA1B HSPA1L

4.09e-075121319626584
Pubmed

HIV infection of T cells: actin-in and actin-out.

FLNA FLNB FLNC

4.09e-075121319366992
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

SMG1 FLNA CORO1C AKAP12 PTPN11 HSPA1A HSPA1B HSPA6 HSPA8

4.32e-07267121933417871
Pubmed

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

7.32e-07143121722516433
Pubmed

CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.

FLNA FLNB FLNC SLC25A21 WWOX CORO1C TRAP1 SLC25A1 HSPA1B HSPA6 HSPA8

7.88e-074681211136042349
Pubmed

CCT3 acts upstream of YAP and TFCP2 as a potential target and tumour biomarker in liver cancer.

FLNB CORO1C TRAP1 HSPA1A HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

8.12e-07288121931501420
Pubmed

Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.

HSPA1A HSPA1B HSPA8

8.15e-076121315963462
Pubmed

New microsatellite size variants as markers for a cross-over hotspot in the C4-H-2D region.

HSPA1A HSPA1B HSPA1L

8.15e-07612138199408
Pubmed

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

HSPA1A HSPA1B HSPA8

8.15e-07612139305631
Pubmed

RING finger protein RNF207, a novel regulator of cardiac excitation.

HSPA1A HSPA1B HSPA8

8.15e-076121325281747
Pubmed

Three Hsp70 genes are located in the C4-H-2D region: possible candidates for the Orch-1 locus.

HSPA1A HSPA1B HSPA1L

8.15e-07612138449501
Pubmed

Heat shock factor 2 is activated during mouse heart development.

HSPA1A HSPA1B HSPA8

8.15e-076121311032181
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

GPD2 FLNA FLNB FLNC COPA CORO1C DDOST TRAP1 SLC25A1 MYO15A HSPA1B HSPA1L HSPA2 HSPA8

8.97e-078071211430575818
Pubmed

A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.

FLNA HSPA1A HSPA1B HSPA2 HSPA8

9.69e-0751121536896912
Pubmed

Prothymosin-α enhances phosphatase and tensin homolog expression and binds with tripartite motif-containing protein 21 to regulate Kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2 signaling in human bladder cancer.

HSPA1A HSPA1L HSPA6 HSPA8

1.40e-0624121430719818
Pubmed

Molecular analysis of the major MHC recombinational hot spot located within the G7c gene of the murine class III region that is involved in disease susceptibility.

HSPA1A HSPA1B HSPA1L

1.42e-06712139551980
Pubmed

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway.

HSPA1A HSPA1B HSPA8

1.42e-067121310205060
InteractionCCDC117 interactions

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

7.05e-09261176int:CCDC117
InteractionMETTL21A interactions

HSPA1A HSPA1B HSPA1L HSPA2 HSPA7 HSPA8

5.69e-08361176int:METTL21A
InteractionDND1 interactions

FLNA ACTR3C TRAP1 RBPMS2 HSPA1L

8.75e-08201175int:DND1
InteractionCCNI2 interactions

HSPA1B HSPA1L HSPA6 HSPA8

1.33e-0791174int:CCNI2
InteractionALKAL2 interactions

HTRA1 CD109 ADGRV1 LTK

3.45e-07111174int:ALKAL2
InteractionLRRC28 interactions

HSPA1B HSPA1L HSPA6 HSPA8

7.41e-07131174int:LRRC28
InteractionCYP2W1 interactions

HSPA1B HSPA1L HSPA2 HSPA8

1.40e-06151174int:CYP2W1
InteractionAXL interactions

FLNA WWOX CFTR DDOST AKAP12 TRAP1 PTPN11 SLC25A1 HSPA1A HSPA1B HSPA6 HSPA8

1.62e-0636911712int:AXL
InteractionHDAC6 interactions

FLNA FLNB COPA CORO1C CFTR CD109 GEMIN5 DDOST AKAP12 JAK2 PTPN11 SLC25A1 POLR1B TDRD6 HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.63e-0692911719int:HDAC6
InteractionPOLR1D interactions

GPN1 MPDZ RNF213 UBN2 ATL1 TFPT BRF1 POLR1B

1.69e-061411178int:POLR1D
InteractionPRODH interactions

HSPA1L HSPA2 HSPA6 HSPA8

1.86e-06161174int:PRODH
InteractionFAM83F interactions

HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.98e-06361175int:FAM83F
InteractionPTPN12 interactions

FLNA FLNB FLNC JAK2 TENM1 HSPA1A HSPA6 HSPA8

2.08e-061451178int:PTPN12
InteractionDNAJB2 interactions

CFTR HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

2.17e-061021177int:DNAJB2
InteractionC3orf38 interactions

HSPA1A HSPA2 HSPA6 HSPA8

2.42e-06171174int:C3orf38
InteractionFBXL4 interactions

SLC25A46 FLNA DUSP14 HSPA1A HSPA1B HSPA2 HSPA8

2.81e-061061177int:FBXL4
InteractionPIAS1 interactions

FLNA FLNB FLNC COPA ACTR3C CORO1C HTRA4 GRM8 DDOST HSPA1A HSPA8

6.76e-0635311711int:PIAS1
InteractionTRIM38 interactions

HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

7.64e-06471175int:TRIM38
InteractionPIK3R2 interactions

CORO1C TRIM23 PTPN11 LTK HSPA1A HSPA1B HSPA1L HSPA6 HSPA8

7.97e-062301179int:PIK3R2
InteractionSHC1 interactions

CORO1C CFTR AKAP12 JAK2 PTPN11 LTK HSPA1A HSPA1B HSPA1L HSPA6 HSPA8

8.56e-0636211711int:SHC1
InteractionNPHP4 interactions

FLNA FLNB FLNC TRAP1 HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

9.80e-062361179int:NPHP4
InteractionKIAA1191 interactions

CACNA1A PKD1L2 SORT1 HSPA6 HSPA8

1.04e-05501175int:KIAA1191
InteractionHSPB7 interactions

FLNA FLNB FLNC TRIM23

1.05e-05241174int:HSPB7
InteractionALDH1B1 interactions

GPD2 WWOX CFTR ATL3 TRAP1 PTPN11 HSPA1A HSPA2

1.53e-051901178int:ALDH1B1
InteractionABHD15 interactions

HSPA1L HSPA2 HSPA6 HSPA8

1.71e-05271174int:ABHD15
InteractionDNAJC13 interactions

TRIM23 PRKAR1B HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

2.02e-051431177int:DNAJC13
InteractionCCDC142 interactions

HSPA1B HSPA1L HSPA8

2.22e-05101173int:CCDC142
InteractionARMC5 interactions

GEMIN5 TRAP1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

2.29e-052011178int:ARMC5
InteractionSIRPA interactions

FLNA TRIM23 JAK2 PTPN11 HSPA1A HSPA8

2.57e-051001176int:SIRPA
InteractionMYLK2 interactions

FLNA FLNB CFTR SLC25A1 HSPA1A HSPA8

2.72e-051011176int:MYLK2
InteractionISG15 interactions

FLNA FLNB COPA CFTR ATL3 RNF213 DDOST TRAP1 TSPYL5 HSPA1A HSPA1B HSPA8

3.07e-0549411712int:ISG15
InteractionKLHL34 interactions

HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

3.25e-05631175int:KLHL34
InteractionFUNDC1 interactions

SLC25A46 HSPA2 HSPA6 HSPA8

3.42e-05321174int:FUNDC1
InteractionSIK2 interactions

SMG1 FLNA CORO1C SLC25A1 HSPA1A HSPA2

3.58e-051061176int:SIK2
InteractionCLTA interactions

DCAF1 FLNA CFTR SORT1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

3.87e-0535111710int:CLTA
InteractionPNPLA5 interactions

HSPA1B HSPA2 HSPA6 HSPA8

3.88e-05331174int:PNPLA5
InteractionCPLANE2 interactions

HSPA2 HSPA6 HSPA8

4.04e-05121173int:CPLANE2
InteractionDNAJB14 interactions

CFTR HSPA1A HSPA1L HSPA2 HSPA8

4.08e-05661175int:DNAJB14
InteractionAP2M1 interactions

DCAF1 CACNA1A FLNA CORO1C CFTR PRKAR1B HSPA1A HSPA1B HSPA1L HSPA6 HSPA8

4.19e-0543011711int:AP2M1
InteractionEPS15 interactions

DCAF1 FLNA TRIM23 SLC6A3 HSPA1A HSPA1B HSPA1L HSPA8

4.37e-052201178int:EPS15
InteractionCBL interactions

FLNA CORO1C CFTR HTRA4 JAK2 PTPN11 LTK HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

4.68e-0551611712int:CBL
InteractionHSPBP1 interactions

GPN1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

5.26e-051661177int:HSPBP1
InteractionDNAJB5 interactions

CACNA1A HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

5.39e-051141176int:DNAJB5
InteractionDHRS13 interactions

WWOX HSPA2 HSPA6 HSPA8

5.51e-05361174int:DHRS13
InteractionPAK1 interactions

FLNA AKAP12 SLC25A1 HSPA1A HSPA2 HSPA6 HSPA7 HSPA8

5.79e-052291178int:PAK1
InteractionNUDT5 interactions

FLNA FLNB FLNC DUSP14 HSPA1A

7.55e-05751175int:NUDT5
InteractionWDHD1 interactions

COPA AKAP12 TRAP1 PTPN11 HSPA1A HSPA2 HSPA6

7.88e-051771177int:WDHD1
InteractionNSUN5P2 interactions

PTPN11 HSPA2 HSPA8

8.25e-05151173int:NSUN5P2
InteractionCHMP4B interactions

FLNA FLNB FLNC COPA NBEAL1 CORO1C CFTR CD109 TRAP1 SLC25A1 HSPA1A HSPA7 HSPA8 PDZD2

8.27e-0572711714int:CHMP4B
InteractionRIMS1 interactions

FLNA RAPGEF4 RAB37 RAB26

8.39e-05401174int:RIMS1
InteractionHSPA6 interactions

DCAF1 FLNA FLNB CFTR HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

8.50e-053111179int:HSPA6
InteractionF12 interactions

TEP1 HSPA1B HSPA2 HSPA6 HSPA8

8.57e-05771175int:F12
InteractionPELI3 interactions

HSPA1B HSPA2 HSPA6 HSPA8

9.26e-05411174int:PELI3
InteractionSPDL1 interactions

FLNA FLNB FLNC COPA TRAP1 HSPA1A HSPA1L HSPA6 HSPA8

9.36e-053151179int:SPDL1
InteractionKBTBD4 interactions

SMG1 FLNA CORO1C AKAP12 PTPN11 HSPA1A HSPA1B HSPA6 HSPA8

9.59e-053161179int:KBTBD4
InteractionHYOU1 interactions

FLNA CFTR CD109 ATP6V1F ADGRV1 HTRA4 LTK HSPA1A HSPA8

9.82e-053171179int:HYOU1
InteractionVASH1 interactions

HSPA1L HSPA6 HSPA8

1.01e-04161173int:VASH1
InteractionDNAJB8 interactions

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

1.03e-04801175int:DNAJB8
InteractionRUFY1 interactions

FLNA COPA RNF213 TRIM23 TRAP1 SLC25A1 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

1.04e-0447611711int:RUFY1
InteractionGAN interactions

RNF213 TRAP1 GTPBP3 HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

1.16e-042531178int:GAN
InteractionDBNL interactions

COPA CFTR GPN1 UBN2 HSPA1A HSPA2 HSPA8

1.23e-041901177int:DBNL
InteractionHSP90AB1 interactions

DCAF1 FLNA CYP17A1 CFTR GPN1 DDOST JAK2 PTPN11 SLC25A1 STK33 MYO15A HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

1.36e-0496011716int:HSP90AB1
InteractionPRKCZ interactions

DCAF1 FLNA FLNC DDOST TRAP1 SLC25A1 HSPA1A HSPA6 HSPA7 HSPA8

1.46e-0441211710int:PRKCZ
InteractionACLY interactions

FLNC WWOX CFTR TRAP1 PTPN11 BRF1 HSPA1A HSPA6 HSPA8

1.49e-043351179int:ACLY
InteractionNCKIPSD interactions

DCAF1 GEMIN5 RBM22 MED25 HSPA1L HSPA6

1.49e-041371176int:NCKIPSD
InteractionMYOZ1 interactions

FLNA FLNC WWOX TRIM23

1.59e-04471174int:MYOZ1
InteractionCALD1 interactions

FLNA FLNB FLNC CFTR UBN2 ITPR2 TRAP1 HSPA8

1.59e-042651178int:CALD1
InteractionGNB2 interactions

CACNA1A FLNA CFTR L2HGDH RNF213 SLC25A1 HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.65e-0450211711int:GNB2
InteractionHEY1 interactions

FLNA SORT1 HSPA1A HSPA1B HSPA2 HSPA8

1.68e-041401176int:HEY1
InteractionSTOML2 interactions

SLC25A46 WWOX CFTR TRAP1 HSPA1A HSPA1L HSPA6 HSPA8

1.68e-042671178int:STOML2
InteractionRRBP1 interactions

SLC25A46 FLNB CFTR GEMIN5 PTPN11 PRKAR1B HSPA1L HSPA2 HSPA8

1.70e-043411179int:RRBP1
InteractionMCM5 interactions

FLNA FLNB FLNC PRKAR1B HSPA1A HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

1.70e-0442011710int:MCM5
InteractionRMDN1 interactions

HTRA4 NIPA2 HSPA1A HSPA8

1.72e-04481174int:RMDN1
InteractionCDK9 interactions

FLNA FLNB MRI1 IL31RA CORO1C HTRA4 DDOST TRAP1 SLC25A1 HSPA1A HSPA2 HSPA6 HSPA8

1.74e-0468511713int:CDK9
InteractionGARS1 interactions

FLNB WWOX CORO1C CFTR TRAP1 HSPA1A HSPA2 HSPA8

1.81e-042701178int:GARS1
InteractionFRMD8P1 interactions

HSPA6 HSPA8

1.99e-0441172int:FRMD8P1
InteractionUBL4A interactions

CORO1C CFTR GEMIN5 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

2.02e-043491179int:UBL4A
InteractionCDC42EP3 interactions

HSPA2 HSPA6 HSPA8

2.02e-04201173int:CDC42EP3
InteractionDNAJB4 interactions

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

2.03e-041451176int:DNAJB4
InteractionESYT1 interactions

SLC25A46 WWOX COPA CFTR ATL3 ATP6V1F DDOST ATL1 HSPA1A HSPA8

2.10e-0443111710int:ESYT1
InteractionRPRD2 interactions

WWOX GPN1 POLR1B HSPA1A HSPA2 HSPA8

2.11e-041461176int:RPRD2
InteractionDNAJB11 interactions

FLNA CORO1C CFTR DDOST LTK HSPA1A HSPA1L HSPA6 HSPA8

2.11e-043511179int:DNAJB11
InteractionTPM2 interactions

FLNA CFTR PSMB9 RNF213 TFPT HSPA1A ASPDH

2.21e-042091177int:TPM2
InteractionZNF598 interactions

FLNA FLNB WWOX COPA DDOST AKAP12 SLC25A1 HSPA1A HSPA2 HSPA8

2.26e-0443511710int:ZNF598
InteractionGSTM3 interactions

FLNB PTPN11 HSPA1A HSPA2 HSPA6 HSPA8

2.27e-041481176int:GSTM3
InteractionTFCP2 interactions

FLNB CORO1C DPYSL4 TRAP1 HSPA1A HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

2.30e-0443611710int:TFCP2
InteractionZNF488 interactions

HSPA2 HSPA6 HSPA8

2.35e-04211173int:ZNF488
InteractionADAMTS17 interactions

ATL3 ADGRV1 HSPA1A

2.35e-04211173int:ADAMTS17
InteractionTXNIP interactions

DCAF1 FLNA COPA PTPN11 HSPA1A HSPA1B HSPA8

2.41e-042121177int:TXNIP
InteractionTRAF3IP1 interactions

TRAP1 HSPA1A HSPA1L HSPA6 HSPA8

2.43e-04961175int:TRAF3IP1
InteractionZBTB18 interactions

FLNA HSPA1A HSPA6 HSPA8

2.54e-04531174int:ZBTB18
InteractionINPPL1 interactions

FLNC WWOX BHMT2 HSPA1B HSPA1L HSPA6 HSPA8

2.55e-042141177int:INPPL1
InteractionGABRA1 interactions

COPA DDOST SLC25A1 HSPA1A HSPA6 HSPA8

2.62e-041521176int:GABRA1
InteractionRFPL2 interactions

HSPA2 HSPA6 HSPA8

2.71e-04221173int:RFPL2
InteractionMYOZ2 interactions

FLNC WWOX MBLAC1

2.71e-04221173int:MYOZ2
InteractionLAD1 interactions

FLNA FLNB FLNC CFTR

2.73e-04541174int:LAD1
InteractionCEP250 interactions

DCAF1 AKAP12 TRAP1 HSPA1A HSPA1L HSPA2 HSPA7 HSPA8

2.74e-042871178int:CEP250
InteractionPTPN1 interactions

SLC25A46 FLNA WWOX COPA CFTR GEMIN5 RNF213 ATP6V1F ATL1 ITPR2 JAK2 LTK

2.81e-0462511712int:PTPN1
InteractionPLD5 interactions

DUSP14 SERPINB13 HSPA1B HSPA2

2.93e-04551174int:PLD5
InteractionTECR interactions

WWOX COPA CFTR DDOST PTPN11 LTK HSPA1A HSPA8

2.94e-042901178int:TECR
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA7 HSPA8

8.73e-1317877583
GeneFamilyCD molecules|Type II classical cadherins

CDH22 CDH9 CDH11 CDH18

3.46e-07138741186
GeneFamilySolute carriers

SLC25A46 SLC25A21 SLC2A9 SLC24A3 SLC25A26 SLC12A5 SLCO1B7 SLC6A3 SLC8B1 SLC24A4 SLC16A4 SLC25A1

4.06e-073958712752
CoexpressionHOWARD_PBMC_INACT_MONOV_INFLUENZA_A_INDONESIA_05_2005_H5N1_AGE_19_39YO_AS03_ADJUVANT_VS_BUFFER_1DY_UP

DPYD IL31RA CES1 PSMB9 PKHD1L1 SORT1 JAK2 SLC24A4 TDRD6 HSPA6 HSPA7

1.47e-0637712111M40997
CoexpressionGSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_UP

FLNB B4GALNT1 COPA GPN1 PSMB9 KSR1 RBM22 PTPRE

4.30e-062001218M6955
CoexpressionBENPORATH_SUZ12_TARGETS

CACNA1A DCHS2 HTRA1 B4GALNT1 AMN CFTR RAPGEF4 HTRA4 SLC12A5 SLC6A3 SLC24A4 B4GALNT2 LTK GRIN3A HSPA6 CDH11 PDZD2

5.61e-06103512117M9898
CoexpressionDEN_INTERACT_WITH_LCA5

HSPA1A HSPA1B HSPA1L HSPA8

5.97e-06261214M1380
CoexpressionKRISHNAN_FURIN_TARGETS_UP

HSPA1A HSPA1B HSPA8

1.12e-05101213MM1243
CoexpressionCAFFAREL_RESPONSE_TO_THC_8HR_5_DN

HSPA1L HSPA2 HSPA8

2.05e-05121213M2260
CoexpressionGSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN

MRI1 ATL3 TEP1 SORT1 PTPRE HSPA1A HSPA1B

3.98e-051991217M6648
CoexpressionFLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN

SLC25A46 SMG1 HTRA1 COPA CYP17A1 MPDZ DDOST LGALS2 SLC16A4 SLC25A1 HSPA8

5.26e-0555312111M1475
CoexpressionBILD_MYC_ONCOGENIC_SIGNATURE

FLNB GEMIN5 RNF213 ADAM8 AKAP12 HSPA1A HSPA6

5.43e-052091217M2069
CoexpressionFLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP

SLC25A46 SMG1 COPA PSMB9 DESI2 DDOST SLC16A4 SLC25A1 HSPA1A HSPA8 CDH11

6.69e-0556812111M4023
CoexpressionHOOI_ST7_TARGETS_UP

FLNC DPYD IL31RA STRIP2 CDH11

7.25e-05931215M8455
CoexpressionAIZARANI_LIVER_C12_NK_NKT_CELLS_4

HSPA1A HSPA1B HSPA6 HSPA8

7.80e-05491214M39116
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FLNA HTRA1 ATP6V1F ADAM8 HSPA1A HSPA1B HSPA1L HSPA2 HSPA6 HSPA8

1.63e-1019612110d79a84aa25ba70483ae899cd5b52ba0bbffdcd7b
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC CES1 CORO1C SLC24A3 TSPAN2 AKAP12 RBPMS2 HSPA2

3.05e-091931219173f1d83133f5ffa88e2a75d28835ad7acd2aa90
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC CES1 TSPAN2 AKAP12 STK33 RBPMS2 HSPA2

4.62e-0818712183912bbb610a4a84791e9bda92a2d57a52c31d29e
ToppCellE18.5-Immune-Immune_Myeloid-DC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC PSMB9 TEP1 ADAM8 STRIP2 PTPRE RAB26

2.83e-0716012179f1fec2cf565193c73cc3c8a4f0476e57478e3b8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1A DCHS2 UBN2 TRIM23 TFPT SLC25A1 TDRD6

3.64e-071661217c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC MPDZ PKHD1L1 AKAP12 CDH22 PTPRE CCM2L

4.81e-0717312177dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC HTRA1 HTRA4 ADH7 BRF1 SCN2B PRKAR1B

5.82e-07178121727497dbfcf9bb4dd0bf7caa0bd78c7e85f5c18ee
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC HTRA1 HTRA4 ADH7 BRF1 SCN2B PRKAR1B

5.82e-071781217d348a9550db940d204706529759dc51e30506b5f
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

FLNC DCHS2 RAPGEF4 PKHD1L1 AKAP12 CCM2L BHMT2

5.82e-071781217c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 IL31RA GRM8 TENM1 RAB26 CDH11 CDH18

6.05e-0717912177954c0026754ab869b88ab7feb13c2f27d6e272d
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPYD CDH22 SLC24A4 LTK CDH9 CDH18 PDZD2

7.01e-0718312171645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPYD CDH22 SLC24A4 LTK CDH9 CDH18 PDZD2

7.27e-07184121734e316ad8e7b8667cd8ad61397281802a252744f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

RAPGEF4 PKHD1L1 AKAP12 CDH22 PTPRE CCM2L BHMT2

8.40e-071881217c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC RAPGEF4 PKHD1L1 AKAP12 PTPRE CCM2L BHMT2

8.71e-07189121755a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

FLNC RAPGEF4 PKHD1L1 AKAP12 CCM2L BHMT2 PRKAR1B

9.02e-07190121791bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA CES1 CORO1C TSPAN2 AKAP12 HSPA1A HSPA2

1.00e-061931217a402e736440684ebe123673b6b0c6fcd8fa057b2
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC CES1 CORO1C SLC24A3 TSPAN2 AKAP12

1.00e-061931217b1893193766ae41bf2ab6ed4083285c9c814e608
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC CES1 SLC24A3 TSPAN2 AKAP12 HSPA2

1.04e-061941217bea369e9a7018d862e4d7f1c9ec2de50f3fd38ec
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMN CYP17A1 LGALS2 SLC16A4 BHMT2 CDH9 ASPDH

1.11e-0619612174ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC HTRA1 CES1 TSPAN2 AKAP12 RBPMS2

1.15e-0619712175a63c2b824c7d0dbbc706e408459c9b9fe65daaa
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FLNA FLNC CORO1C TSPAN2 SORT1 RBPMS2 HSPA2

1.27e-0620012172bc7f462a551292de2501028164573935232f899
ToppCellmetastatic_Brain-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

HTRA1 CORO1C RNF213 ATP6V1F HSPA1A HSPA1B HSPA6

1.27e-062001217bfb54a8ce44caf01083c6567b236395c6ee1d47a
ToppCell390C-Fibroblasts-Fibroblast-K_(Pericytes)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FLNA FLNC CORO1C TSPAN2 SORT1 RBPMS2 HSPA2

1.27e-0620012178b80a65b69b36ed405214564b939452c90aa40d6
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTRA4 GRM8 SLC24A4 IRGC CDH9 LRRC75A

4.70e-0615812169e0589f770920f8ac41cfe5cd0a29e9e7a04a308
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Pygm_C1ql1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

HTRA1 KLHL40 SLC24A3 GRM8 TSPAN2 TENM1

6.68e-061681216f3879a8e11eaf866f37c52e67021be43f0b8784a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AMN SLC2A9 STRIP2 BHMT2 CDH9 PDZD2

7.90e-0617312168888434641ea554a9b62c436e87920378eef29cd
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPYD CDH22 SLC24A4 LTK CDH9 PDZD2

8.16e-0617412169cc7251661ea2b1565eef1dfb8cf6dec3ade13d4
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPYD CDH22 SLC24A4 LTK CDH9 PDZD2

8.71e-06176121607abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCHS2 GRM8 TENM1 RAB26 CDH11 CDH18

9.00e-061771216bde307e67ad8e48a5ff4c0827015f4688f6b3e46
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FLNA FLNC TSPAN2 CDH22 SCN2B BHMT2

9.29e-0617812168ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FLNA FLNC TSPAN2 CDH22 SCN2B BHMT2

9.29e-0617812166c91331196696e0cf239d105f458e3230659fa38
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC PKHD1L1 AKAP12 SLC6A3 PTPRE BHMT2

9.29e-0617812164b3ea0921bc598ebb9f63780ecdf8ad4349f3666
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DPYD CDH22 SLC24A4 LTK CDH9 PDZD2

9.29e-0617812165d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC CES1 SLC24A3 TSPAN2 HSPA2

9.59e-061791216e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CDH22 SLC24A4 LTK CDH9 CDH18 PDZD2

9.59e-0617912169ba8693fba2175bca9ff9735cc04e657abeb9084
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

RAPGEF4 CD109 AKAP12 HSPA1A HSPA1B HSPA6

9.59e-061791216754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC25A21 AMN SLC2A9 BHMT2 CDH9 PDZD2

9.59e-061791216d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

ACTR3C CFTR GRM8 CDH22 B4GALNT2 PDZD2

1.05e-051821216ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell3'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAPGEF4 PKHD1L1 AKAP12 SLC6A3 PTPRE BHMT2

1.05e-05182121682d6f72649c7dd4d64a84a9795edebdef2f285d6
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HTRA1 MPDZ PKHD1L1 AKAP12 PRKAR1B HSPA1A

1.05e-05182121653c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMN SLC2A9 BHMT2 TENM1 CDH9 PDZD2

1.09e-051831216facd6dbe0851b537d70a899ac7485714ab27d071
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNC DCHS2 PKHD1L1 AKAP12 PTPRE BHMT2

1.09e-05183121638a54216458ad57f356bb4ddf272e1af8036ddeb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AMN SLC2A9 KCNK10 BHMT2 CDH9 PDZD2

1.09e-05183121685446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNB FLNC PKHD1L1 AKAP12 PTPRE BHMT2

1.09e-051831216bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR ADGRV1 PKD1L2 PKHD1L1 TENM1 MYO15A

1.12e-0518412162cbed6462fea2622871bb7e49b0df3d984239281
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_mature-Lymphatic_EC_mature_L.2.5.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLNC HTRA1 PKHD1L1 AKAP12 BHMT2 PRKAR1B

1.12e-0518412161a4297b9d3cc4744bea0408fd5ee7b33ba2a1d78
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR ADGRV1 PKD1L2 PKHD1L1 TENM1 MYO15A

1.12e-051841216ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR ADGRV1 PKD1L2 PKHD1L1 TENM1 MYO15A

1.12e-0518412162b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AMN SLC2A9 KCNK10 BHMT2 CDH9 PDZD2

1.12e-0518412169434731f651820b05335085582960f08fbf895de
ToppCell343B-Myeloid-Dendritic-cDC2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ADAM8 LGALS2 HSPA1A HSPA1B HSPA6

1.21e-0510912156e90d04c5094c7410d667dae80de3279bddd24bd
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ACTR3C CFTR DESI2 ADGRV1 ALOX15B PDZD2

1.23e-0518712165df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AMN SLC2A9 BHMT2 TENM1 CDH9 PDZD2

1.23e-051871216dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AMN SLC2A9 BHMT2 TENM1 CDH9 PDZD2

1.23e-051871216f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellmoderate-Epithelial-Ionocyte|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IL31RA ACTR3C CFTR ITPR2 CDH22 B4GALNT2

1.23e-0518712163e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

FLNC RAPGEF4 PKHD1L1 AKAP12 CCM2L PRKAR1B

1.23e-0518712161e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC CD109 RBPMS2 HSPA1A HSPA1B HSPA1L

1.27e-05188121661f010c165826b434ca3d27553d4c9e13d2c0c51
ToppCelldroplet-Lung-nan-18m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC CD109 RBPMS2 HSPA1A HSPA1B HSPA1L

1.27e-0518812167553ef7de3575af4cf34704b405b551c1af8eb83
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

RAPGEF4 PKHD1L1 AKAP12 PTPRE CCM2L BHMT2

1.27e-05188121680910dcbb51990f2baed240f319456c0d3fa2065
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACTR3C ADGRV1 STK33 TENM1 CDH9 PDZD2

1.27e-051881216af740fa78542438fdff627ea1f74f4eee43316be
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FLNB MPDZ PKHD1L1 AKAP12 CDH22 CCM2L

1.27e-051881216aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

FLNB RAPGEF4 PKHD1L1 AKAP12 ITPR2 CDH11

1.31e-05189121675c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA CES1 CORO1C TSPAN2 AKAP12 TENM1

1.35e-051901216e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RAPGEF4 PKHD1L1 AKAP12 CDH22 PTPRE CCM2L

1.35e-0519012166e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellCOVID-19-kidney-Stressed_EC|kidney / Disease (COVID-19 only), tissue and cell type

RAPGEF4 CD109 AKAP12 PTPRE HSPA1A HSPA1B

1.39e-051911216d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6|TCGA-Stomach / Sample_Type by Project: Shred V9

GPD2 RNF213 ADAM8 STRIP2 JAK2 NIPA2

1.43e-0519212164e689bca7a242f8482e25f273656e2caba8821c0
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC CES1 TSPAN2 AKAP12 RBPMS2

1.43e-051921216d0fb6885f023d55a2b7984c99db9c6463258f788
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW08|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

CES1 SERPINB13 HSPA1A HSPA1B HSPA6 HSPA7

1.47e-0519312166e9912f5444c591e698b9a7ffa3e9fc3d8ee57b0
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC TSPAN2 AKAP12 RBPMS2 GRIN3A

1.47e-0519312160256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA CES1 CORO1C TSPAN2 AKAP12 HSPA2

1.51e-05194121693bc72a933ccc6a760e5353f072afb606571c6fc
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC CES1 TSPAN2 AKAP12 RBPMS2

1.51e-051941216d2bafd31bb8333f66b6c714944bceb2f1aa11740
ToppCellCTRL-Myeloid-Monocyte_Macrophage|CTRL / Disease state, Lineage and Cell class

HTRA1 CD109 ADAM8 LGALS2 STRIP2 PTPRE

1.51e-051941216927480f56cccd3940b689f3c40ee132fe3e63745
ToppCell(6)_Endothelial_cells-(6)_Endothelial-F_(Lymphatics)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

FLNC HTRA1 PKHD1L1 AKAP12 PTPRE BHMT2

1.51e-0519412169441202d6fa2ffbef9277d48ae9bc98876c26ec5
ToppCellASK440-Endothelial-Lymphatic|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

FLNC RAPGEF4 PKHD1L1 AKAP12 PTPRE HSPA2

1.51e-0519412164aa68e39e36094359dfbedf1e9bdf3ea5c32ed1a
ToppCell343B-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ADAM8 LGALS2 PRMT9 HSPA1A HSPA1B HSPA6

1.51e-051941216ccb04f0788c98e0f63f18b09484d75ac536412a1
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNC HTRA1 CES1 PKHD1L1 AKAP12 PTPRE

1.56e-051951216fc75f04eb475c8139cc5c35e6be22e73fb2be9e6
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNC HTRA1 CES1 PKHD1L1 AKAP12 PTPRE

1.56e-05195121683d45ff5e5bc704448431149fffb2e4c1278f279
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC PKHD1L1 AKAP12 CDH22 PTPRE CCM2L

1.61e-05196121609a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC PKHD1L1 AKAP12 CDH22 PTPRE CCM2L

1.61e-051961216e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNC UBN2 PKHD1L1 AKAP12 PTPRE BHMT2

1.61e-051961216b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNC UBN2 PKHD1L1 AKAP12 PTPRE BHMT2

1.61e-051961216a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA CES1 SLC24A3 TSPAN2 AKAP12 HSPA2

1.65e-051971216f4f686d20821af3e6f859b96edc31827a430e3de
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC RAPGEF4 PKHD1L1 AKAP12 CDH22 CCM2L

1.70e-0519812169ab0db78394e730f6866b2db80047149024ad5f6
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKHD1L1 AKAP12 CDH22 PTPRE CCM2L PRKAR1B

1.70e-051981216b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PKHD1L1 AKAP12 CDH22 PTPRE CCM2L PRKAR1B

1.70e-051981216fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC RAPGEF4 PKHD1L1 AKAP12 CDH22 CCM2L

1.70e-051981216e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Bronchial_vessel|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FLNB RAPGEF4 CD109 PKHD1L1 CCM2L CDH11

1.75e-05199121653b6a661d381b1ed3ea96e61e8bd1750de7d9fda
ToppCellBiopsy_Other_PF-Endothelial-Lymphatic_Endothelial_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

FLNC HTRA1 PKHD1L1 AKAP12 CDH22 BHMT2

1.75e-051991216aa80c77fe4f6a141c780c7d8ecfff5d5a1c3b845
ToppCellParenchyma_Control_(B.)-Endothelial-TX-Bronchial_vessel|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FLNB RAPGEF4 CD109 PKHD1L1 CCM2L CDH11

1.75e-0519912169c753043024871b1f1436fc39defac4da85e10cd
ToppCellLung_Parenchyma-Control-Endothelial-Endothelial-Bronchial_vessel-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FLNB RAPGEF4 CD109 PKHD1L1 CCM2L CDH11

1.75e-051991216d017dd91f9b10038f1f83753a766e534da2dbe89
ToppCellCOVID-19-lung|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNA DPYD PSMB9 RNF213 HSPA1A HSPA1B

1.75e-051991216155b03b859157013e9142e9248551369127d9204
ToppCellSigmoid-T_cell-Th1|T_cell / Region, Cell class and subclass

DPYD HSPA1A HSPA1B HSPA2 HSPA6 HSPA8

1.80e-052001216bc9433a8ec3a6f10816730a32b821c63d78e6e87
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1--L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

CACNA1A SLC24A3 TSPAN2 SLC24A4 TENM1 GRIN3A

1.80e-052001216f3c710f0fc8a7bfb5371d1aff6e3d8f266953153
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A RAPGEF4 SLC24A3 PTPRE TENM1 PDZD2

1.80e-052001216f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A RAPGEF4 SLC24A3 PTPRE TENM1 PDZD2

1.80e-052001216cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CACNA1A SLC24A3 TSPAN2 SLC24A4 TENM1 GRIN3A

1.80e-05200121670a06fd7fb8de2c8ec3e3182e4476ced049daeae
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A RAPGEF4 SLC24A3 PTPRE TENM1 PDZD2

1.80e-052001216c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-CALB1|Neuronal / cells hierarchy compared to all cells using T-Statistic

CACNA1A SLC24A3 TSPAN2 SLC24A4 TENM1 GRIN3A

1.80e-0520012161639982d9d994918f7912d12d9d7cfcbc9da4145
ToppCellBiopsy_Control_(H.)-Endothelial-Lymphatic_Endothelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

FLNC HTRA1 PKHD1L1 AKAP12 BHMT2 PRKAR1B

1.80e-0520012168cf218887ab030b7625610cb65b595170a17ebec
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)|Neuronal / cells hierarchy compared to all cells using T-Statistic

DPYD CDH22 SLC24A4 LTK CDH18 PDZD2

1.80e-0520012160f23e72649a274043bf23e0952a9b5707c516acf
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

CACNA1A RAPGEF4 SLC24A3 PTPRE TENM1 PDZD2

1.80e-0520012164fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ComputationalProtein folding.

TRAP1 HSPA1L HSPA6 HSPA8

5.86e-0529804MODULE_355
DrugPentylenetetrazole [54-95-5]; Up 200; 29uM; MCF7; HT_HG-U133A

NDOR1 TEP1 GRM8 ITPR2 KSR1 SERPINB13 SCN2B BHMT2 TENM1

1.16e-0619812192255_UP
DrugThiostrepton

HSPA1A HSPA1L HSPA2 HSPA6 HSPA8

2.84e-06421215ctd:D013883
DrugMethionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A

TEP1 ADAM8 GRM8 SERPINB13 SLC16A4 BHMT2 TENM1 MYO15A

8.82e-0619212184151_UP
DrugQuinic acid [86-68-0]; Up 200; 19.6uM; MCF7; HT_HG-U133A

GPD2 TEP1 ADAM8 GRM8 SLC12A5 ITPR2 ADH7 BRF1

1.06e-0519712183540_UP
DrugKetotifen fumarate [34580-14-8]; Up 200; 9.4uM; MCF7; HT_HG-U133A

DCAF1 WWOX COPA L2HGDH DPYSL4 TEP1 KSR1 CYP2R1

1.06e-0519712187199_UP
DrugICI 182,780; Up 200; 0.01uM; HL60; HT_HG-U133A

NDOR1 WWOX ADAM8 GRM8 TRIM23 ADH7 KSR1 BRF1

1.10e-0519812186197_UP
DrugApigenin

CYP17A1 CFTR TFPT HSPA1A HSPA1B HSPA1L HSPA2 HSPA8

1.52e-052071218ctd:D047310
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNB FLNC

6.08e-0831173DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNB FLNC

6.08e-0831173DOID:0111190 (implicated_via_orthology)
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B HSPA8

6.04e-0751173DOID:0081267 (biomarker_via_orthology)
DiseaseAlcoholic Intoxication, Chronic

CFTR MPDZ REN GRM8 SLC6A3 ADH7 CDH9 CDH11 CDH18

1.29e-062681179C0001973
DiseaseMajor depression, single episode

HSPA1A HSPA1B HSPA1L

5.02e-0691173C0024517
Disease2-hydroxyglutaric aciduria (is_implicated_in)

L2HGDH SLC25A1

1.56e-0521172DOID:0050573 (is_implicated_in)
Diseasehereditary spastic paraplegia 3A (implicated_via_orthology)

ATL3 ATL1

4.66e-0531172DOID:0110791 (implicated_via_orthology)
DiseaseMalignant Hypertension

CYP17A1 REN

4.66e-0531172C0020540
Diseaseepilepsy (implicated_via_orthology)

CACNA1A WWOX SLC24A3 GRM8 SLC12A5 SLC24A4

4.89e-051631176DOID:1826 (implicated_via_orthology)
DiseaseCombined D-2- and L-2-hydroxyglutaric aciduria

L2HGDH SLC25A1

9.30e-0541172C2746066
Diseaseportal hypertension (is_implicated_in)

REN JAK2

1.55e-0451172DOID:10762 (is_implicated_in)
Diseaseliver cancer (biomarker_via_orthology)

CES1 JAK2

1.55e-0451172DOID:3571 (biomarker_via_orthology)
Diseaseschizophrenia (is_implicated_in)

GRM8 HSPA1A HSPA1B HSPA1L

2.67e-04781174DOID:5419 (is_implicated_in)
Diseasehyperuricemia (implicated_via_orthology)

SLC2A9 JAK2

3.23e-0471172DOID:1920 (implicated_via_orthology)
Diseasejuvenile myelomonocytic leukemia (is_implicated_in)

AKAP12 PTPN11

3.23e-0471172DOID:0050458 (is_implicated_in)
Diseasemetabolite measurement

MRI1 WWOX SLC2A9 CES1 GPN1 PSMB9 PKD1L2 SLC12A5 ITPR2

4.03e-045601179EFO_0004725
Diseasecerebellar ataxia (implicated_via_orthology)

CACNA1A GEMIN5

4.30e-0481172DOID:0050753 (implicated_via_orthology)
DiseaseHereditary Sensory Autonomic Neuropathy, Type 1

ATL3 ATL1

4.30e-0481172C0020071
Diseasebody shape measurement

GRM8 TRAP1

4.30e-0481172EFO_0801227
Diseaserenin measurement

NBEAL1 REN

4.30e-0481172EFO_0010616
DiseaseColorectal Carcinoma

FLNC DPYD CFTR CD109 AKAP12 SLC12A5 CDH22 BRF1 TENM1 B4GALNT2

4.95e-0470211710C0009402
DiseaseAnorectal Malformations

DESI2 JAK2 CDH18

5.80e-04411173C3495676
Diseaseoral microbiome measurement

SLC2A9 SEC61A2 PDZD2

6.23e-04421173EFO_0801229
Diseasehereditary spastic paraplegia (implicated_via_orthology)

ATL3 ATL1 NIPA2

6.68e-04431173DOID:2476 (implicated_via_orthology)
Diseasemyopathy (implicated_via_orthology)

FLNA FLNB FLNC

9.23e-04481173DOID:423 (implicated_via_orthology)
DiseaseHepatic fibrosis

GRM8 SLC24A4 RAB37

9.80e-04491173HP_0001395
DiseaseKawasaki disease (is_implicated_in)

HSPA1A HSPA1L

1.00e-03121172DOID:13378 (is_implicated_in)
Diseaseneutrophil count

CACNA1A FLNB COPA SLC25A26 TSPAN2 AKAP12 ITPR2 JAK2 TRAP1 SLC25A1 B4GALNT2 RAB37 HSPA7 HSPA8

1.16e-03138211714EFO_0004833
DiseaseDNA methylation

DPYD DCHS2 SLC2A9 MATN1 SLC24A3 GRM8 SEC61A2 CDH11 CDH18

1.23e-036561179GO_0006306
DiseaseMouth Neoplasms

GPN1 ADH7 HSPA8

1.30e-03541173C0026640
DiseaseMalignant neoplasm of mouth

GPN1 ADH7 HSPA8

1.30e-03541173C0153381
Diseaseserum metabolite measurement

GPD2 DPYD SLC2A9 L2HGDH SLC24A3 PKD1L2 ATL1 ADH7 SERPINB13 BHMT2 HSPA8

1.36e-0394511711EFO_0005653
Diseasecutaneous melanoma, hair color

ADGRV1 AKAP12 SLC24A4

1.94e-03621173EFO_0000389, EFO_0003924
DiseaseDementia

HTRA1 SLC6A3

2.04e-03171172C0497327
Diseasemajor depressive disorder (is_implicated_in)

HSPA1A HSPA1L

2.04e-03171172DOID:1470 (is_implicated_in)
Diseaselow affinity immunoglobulin gamma Fc region receptor II-a measurement

HSPA6 HSPA7

2.04e-03171172EFO_0021969
DiseaseMoyamoya Disease

HTRA1 RNF213

2.04e-03171172C0026654
Diseasemigraine disorder, systolic blood pressure

RNF213 SLC24A3

2.29e-03181172EFO_0006335, MONDO_0005277
Diseaseosteochondrodysplasia (is_implicated_in)

FLNA FLNB

2.55e-03191172DOID:2256 (is_implicated_in)
Diseaseankylosing spondylitis (is_implicated_in)

PSMB9 JAK2

2.55e-03191172DOID:7147 (is_implicated_in)
Diseasechemerin measurement

ACTR3C GRM8

2.55e-03191172EFO_0004573
Diseasecoronary artery disease

DPYD SLC25A21 HTRA1 NBEAL1 CORO1C CFTR CD109 RNF213 AKAP12 RBPMS2 B4GALNT2 RAB37

2.81e-03119411712EFO_0001645
Diseaseattention deficit hyperactivity disorder (is_implicated_in)

GRM8 SLC6A3

2.83e-03201172DOID:1094 (is_implicated_in)
Diseasestomach cancer (is_implicated_in)

TEP1 JAK2 PTPN11

2.97e-03721173DOID:10534 (is_implicated_in)
Diseasebipolar disorder, body mass index

WWOX GRM8 PDZD2

2.97e-03721173EFO_0004340, MONDO_0004985
Diseasemigraine disorder

CACNA1A HTRA1 RNF213 SLC24A3 CCM2L TSPYL5

3.05e-033571176MONDO_0005277
Diseasevitiligo (is_implicated_in)

PSMB9 HSPA1A

3.12e-03211172DOID:12306 (is_implicated_in)
Diseaseesophagus squamous cell carcinoma (is_marker_for)

HTRA1 PSMB9 JAK2

3.21e-03741173DOID:3748 (is_marker_for)
DiseaseAttention Deficit Disorder

GRM8 SLC6A3

3.42e-03221172C0041671
DiseaseMinimal Brain Dysfunction

GRM8 SLC6A3

3.42e-03221172C1321905
DiseaseDisproportionate short stature

FLNA FLNB PTPN11

3.59e-03771173C0878659
DiseaseMalignant neoplasm of breast

FLNA FLNB DPYD WWOX CYP17A1 CD109 LGALS2 AKAP12 SLC6A3 TENM1 HSPA1B

3.66e-03107411711C0006142

Protein segments in the cluster

PeptideGeneStartEntry
IGDEDTVTGFLLGGI

ATP6V1F

11

Q16864
EATGIVESIGEGVTT

ADH7

81

P40394
VVLTGILATVGTEFD

CACNA1A

176

O00555
TVLGSITDILVTEFG

CACNA1A

1636

O00555
TIFGESAGGESVSVL

CES1

216

P23141
TVDAGLFGEGIVESL

PRMT9

256

Q6P2P2
FISILTTGEGEGRVG

CFTR

1116

P13569
LVGGAVREISGFATT

B4GALNT1

381

Q00973
TELDVVGGSVLGNVF

B4GALNT2

421

Q8NHY0
FEGLEGSIDTGITVS

AKAP12

1281

Q02952
LTGGGGTEEILDIIF

GTPBP3

471

Q969Y2
VVGGTATEGLDFIGA

ADGRV1

2626

Q8WXG9
ATEGLDFIGAGEILT

ADGRV1

2631

Q8WXG9
GIIGFSEESQSGLEL

ADGRV1

5366

Q8WXG9
VAIIIEASGGGAFLV

CORO1C

46

Q9ULV4
EGDIGGIAQITSSLF

DUSP14

21

O95147
IRGVVIVLGAGDTAF

DPYD

331

Q12882
ELVLASGAGFGVSDV

AMN

76

Q9BXJ7
ITGVDFTGTTVGFAR

ADAM8

291

P78325
EGVGIREGGILTDSF

CCM2L

486

Q9NUG4
TSSIGIGVFHSGIEV

DESI2

21

Q9BSY9
ASVIGVFITHGDVGV

SLC24A4

156

Q8NFF2
IGEHIVTGSIQGFLS

NBEAL1

2596

Q6ZS30
GSGGALEEEVRTLFV

RBPMS2

21

Q6ZRY4
GAFLAGTFISTVGID

RAB26

86

Q9ULW5
ITTLYVGGLGDTITE

RBM22

231

Q9NW64
DGAFLSGTFIATVGI

RAB37

51

Q96AX2
GSGPSGEEIFATIII

JAK2

276

O60674
GEEIFATIIITGNGG

JAK2

281

O60674
GSVNGFISTLGLVDD

ITPR2

21

Q14571
TFAIAGLGSGLTEAI

SLC25A21

111

Q9BQT8
TVGISIILGVAEGEF

DCAF1

656

Q9Y4B6
SAGVGRTGTFIVIDA

PTPRE

336

P23469
NTSEFDILVIGGGAT

GPD2

66

P43304
VVDISESGLITIAGG

GPD2

421

P43304
SGVELFAIGVGSVDK

MATN1

171

P21941
SVFEIILITSLIGGG

IL31RA

516

Q8NI17
TSSFDIVIVGGGIVG

L2HGDH

46

Q9H9P8
EIFLEGGVISGAITS

MYO15A

1376

Q9UKN7
GEQVDSVELGFTGLT

LRRC75A

201

Q8NAA5
ERTLTGIVIDSGDGV

ACTR3C

31

Q9C0K3
FDGVIGVLVADTSLT

ASPDH

206

A6ND91
GVFVSAIFSLGLGES

LTK

141

P29376
GGIVGRSADFVVESI

FLNB

561

O75369
VVESIGSEVGSLGFA

FLNB

571

O75369
FDLGGGTFDVSILTI

HSPA2

201

P54652
GTFDVSILTIEDGIF

HSPA2

206

P54652
GGGTFDVSILTIDDG

HSPA1B

201

P0DMV9
VVITDFGLFGISGVV

KSR1

746

Q8IVT5
ELGDTETVGLSFGNI

PDZD2

76

O15018
AIGTEVGTLGFSIEG

FLNC

596

Q14315
VDDVIGTLSGFFTII

NIPA2

276

Q8N8Q9
DLGGGTFDVSILTID

HSPA1L

201

P34931
AGSVVADVVFVIEGT

MED25

11

Q71SY5
AIGGFATLETESGEL

KLHL40

561

Q2TBA0
VVTLTTVGFGDFVAG

KCNK10

271

P57789
TGSIADGTDGFVINL

LGALS2

21

P05162
AGIGRTGTFIVIDIL

PTPN11

461

Q06124
DGSSGGVIYLVTITA

PSMB9

186

P28065
INVETISAFIDGGGS

DDOST

111

P39656
ISAFIDGGGSVLVAA

DDOST

116

P39656
GVEAFTQISREIGGV

GRM8

231

O00222
VGVSAVLGTGLDELF

GPN1

241

Q9HCN4
TSVIGVFITKGDVGV

SLC24A3

166

Q9HC58
DLGGGTFDVSVLSID

HSPA7

201

P48741
ESIRLEVGVTGESGA

IRGC

51

Q6NXR0
LGSGISFAAGDVVLI

NDOR1

236

Q9UHB4
ELDGGTGVTYTVLLG

PKD1L2

376

Q7Z442
GFGLSILTTIGEHIV

GRIN3A

941

Q8TCU5
LFLTEGGVARVSEGA

DCHS2

416

Q6V1P9
GVVVFGEPITASLGT

DPYSL4

271

O14531
VATGFVISEDLGLGL

CD109

721

Q6YHK3
SGSGFIVSEDGLIIT

HTRA4

201

P83105
VASGSGFIVSEDGLI

HTRA1

201

Q92743
IAGVTGFIGLDIIAS

ATL1

461

Q8WXF7
RLESGEVVIGDGSFL

BHMT2

16

Q9H2M3
IFTAGAGTGEVEVVI

FLNA

406

P21333
IFSVGELIIAGTETT

CYP2R1

301

Q6VVX0
VRGITGVDLFGTTDA

COPA

181

P53621
HILTTIGDIFGAGVE

CYP17A1

291

P05093
IGDIFGAGVETTTSV

CYP17A1

296

P05093
ILSGEGAGTIFVIDD

CDH11

91

P55287
IASGLTGFIGLEVVA

ATL3

456

Q6DD88
GTALGTVVVAGDVFE

MBLAC1

181

A4D2B0
ILTGEGAGTIFIIDD

CDH18

91

Q13634
GAGTIFIIDDTTGDI

CDH18

96

Q13634
GGIETLAAVFSGLVI

SLC2A9

361

Q9NRM0
VTNISEGGSFGELAL

PRKAR1B

191

P31321
ISGEGAGTIFLIDEL

CDH22

101

Q9UJ99
DLGGGTFDVSVLSID

HSPA6

201

P17066
GGGTFDVSILTIDDG

HSPA1A

201

P0DMV8
VAGGVAGVSVDLILF

SLC25A26

11

Q70HW3
ILTGDGAGSLFVIDE

CDH9

91

Q9ULB4
GLTIVGSVLEGTFLE

SLC12A5

726

Q9H2X9
GGGTFDVSILTIEDG

HSPA8

201

P11142
LGALFGAGVLVTTVV

SLC8B1

171

Q6J4K2
VVDRSTGIGIEGFSE

ALOX15B

426

O15296
GIECITGILGSGFIT

TAS2R40

26

P59535
AVTICTLGIGTAFGE

RAPGEF4

101

Q8WZA2
TLGIGTAFGESILDN

RAPGEF4

106

Q8WZA2
TGFGTIFTSDDRGIV

SORT1

371

Q99523
ILGKGSFGIVIEATD

STK33

121

Q9BYT3
VFLLDEGRTITAGAG

TDRD6

96

O60522
INTGRGTEFEGAVIA

SEC61A2

201

Q9H9S3
IGFTLGQDTDTLVGL

STRIP2

441

Q9ULQ0
GFLSQDIITVGGITV

REN

156

P00797
TALGVTGVEGVFRLS

SMG1

2381

Q96Q15
QDGSFDLVAIGGISV

TENM1

921

Q9UKZ4
DLITGGIITELGVFA

MRI1

331

Q9BV20
SSLVGLIDGSFEIGN

SLCO1B7

16

G3V0H7
SVVEVTLGFLSTAGG

RNF213

5026

Q63HN8
STVAVIVGASVGGFL

SCN2B

156

O60939
LEIFGFGTDTAGVTT

UBN2

1271

Q6ZU65
LETEVEFVSGGLGGS

TFPT

41

P0C1Z6
GSELLVVTVGLDGAT

TEP1

2206

Q99973
DTGVFVSDIVKGGIA

MPDZ

1746

O75970
EKTTSILGAFVVTGG

SLC16A4

86

O15374
GVTLGAEGIISEFTP

SLC25A46

171

Q96AG3
EGTEAAAATGIGFTV

SERPINB13

341

Q9UIV8
GTSILFGVLIEAIGV

SLC6A3

481

Q01959
AFSSVDIGSLAIGVG

GEMIN5

386

Q8TEQ6
LITGVFGAIAGAASV

SLC25A1

221

P53007
VVVVTGANSGIGFET

WWOX

126

Q9NZC7
QGSYEEGTILTIVGS

PKHD1L1

1076

Q86WI1
GTVNELITIIGHGFS

PKHD1L1

1576

Q86WI1
IIVSEVQFVESSGGG

BRF1

36

Q92994
SGVFEIAEASGVRTG

TRAP1

236

Q12931
AEVTTGVFAFIGKGV

TSPAN2

101

O60636
EDSVVVVGKGVFGSL

TOGARAM1

1101

Q9Y4F4
GAAEESIGISGESII

TRIM23

111

P36406
SGISGLELEADIFIG

POLR1B

981

Q9H9Y6
GESVGIFGTAVILAT

TMEM101

241

Q96IK0
LAADTVFVGTAGTVG

TSPYL5

116

Q86VY4