Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmotor neuron migration

CELSR1 CELSR3 CELSR2

1.88e-0515733GO:0097475
GeneOntologyBiologicalProcesscilium assembly

DNHD1 FLNA ARL3 CELSR3 CELSR2 WDR35 AKT1 CFAP61 DNMBP

2.62e-05444739GO:0060271
GeneOntologyBiologicalProcesscilium organization

DNHD1 FLNA ARL3 CELSR3 CELSR2 WDR35 AKT1 CFAP61 DNMBP

4.51e-05476739GO:0044782
GeneOntologyBiologicalProcessacetyl-CoA biosynthetic process

ACAT1 ACLY VDAC1

4.64e-0520733GO:0006085
GeneOntologyBiologicalProcesssodium ion transport

AKT3 SLC9B2 SLC6A5 OSR1 SCN10A AKT1 UTRN

5.34e-05275737GO:0006814
GeneOntologyBiologicalProcessnegative regulation of calcium import into the mitochondrion

AKT1 VDAC1

7.38e-054732GO:0110099
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

DNHD1 FLNA ARL3 CELSR3 CELSR2 CARMIL1 WDR35 AKT1 CFAP61 DNMBP

1.20e-046707310GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

DNHD1 FLNA ARL3 CELSR3 CELSR2 CARMIL1 WDR35 AKT1 CFAP61 DNMBP

1.44e-046857310GO:0030031
DomainGAIN_dom_N

CELSR1 CELSR3 CELSR2

8.50e-0611713IPR032471
DomainGAIN

CELSR1 CELSR3 CELSR2

8.50e-0611713PF16489
DomainABC_tran_Xtn

ABCF1 ABCF2

4.26e-053712PF12848
DomainABC_tran_Xtn

ABCF1 ABCF2

4.26e-053712IPR032781
DomainHormR

CELSR1 CELSR3 CELSR2

1.14e-0425713SM00008
DomainHRM

CELSR1 CELSR3 CELSR2

1.61e-0428713PF02793
DomainEGF_LAM_2

CELSR1 CELSR3 CELSR2

1.99e-0430713PS50027
DomainEGF_LAM_1

CELSR1 CELSR3 CELSR2

1.99e-0430713PS01248
DomainGPS

CELSR1 CELSR3 CELSR2

2.89e-0434713SM00303
DomainGPS

CELSR1 CELSR3 CELSR2

3.16e-0435713PF01825
DomainLaminin_EGF

CELSR1 CELSR3 CELSR2

3.16e-0435713PF00053
DomainEGF_Lam

CELSR1 CELSR3 CELSR2

3.16e-0435713SM00180
DomainGPS

CELSR1 CELSR3 CELSR2

3.44e-0436713PS50221
DomainGPS

CELSR1 CELSR3 CELSR2

3.73e-0437713IPR000203
DomainLAM_G_DOMAIN

CELSR1 CELSR3 CELSR2

4.04e-0438713PS50025
DomainLaminin_EGF

CELSR1 CELSR3 CELSR2

4.04e-0438713IPR002049
DomainG_PROTEIN_RECEP_F2_1

CELSR1 CELSR3 CELSR2

4.70e-0440713PS00649
DomainGPCR_2_extracellular_dom

CELSR1 CELSR3 CELSR2

4.70e-0440713IPR001879
DomainLaminin_G_2

CELSR1 CELSR3 CELSR2

4.70e-0440713PF02210
DomainG_PROTEIN_RECEP_F2_3

CELSR1 CELSR3 CELSR2

4.70e-0440713PS50227
DomainLamG

CELSR1 CELSR3 CELSR2

6.23e-0444713SM00282
DomainG_PROTEIN_RECEP_F2_2

CELSR1 CELSR3 CELSR2

9.08e-0450713PS00650
Domain7tm_2

CELSR1 CELSR3 CELSR2

9.08e-0450713PF00002
DomainLaminin_G

CELSR1 CELSR3 CELSR2

1.40e-0358713IPR001791
DomainGPCR_2_secretin-like

CELSR1 CELSR3 CELSR2

1.54e-0360713IPR000832
DomainGPCR_2-like

CELSR1 CELSR3 CELSR2

1.54e-0360713IPR017981
DomainG_PROTEIN_RECEP_F2_4

CELSR1 CELSR3 CELSR2

1.62e-0361713PS50261
DomainPeptidase_aspartic_dom

NRIP3 CTSD

1.87e-0317712IPR021109
DomainGprotein_alpha_su

ARL3 GNA14

1.87e-0317712IPR001019
DomainApc4_WD40_dom

EML5 WDR35

2.59e-0320712IPR024977
DomainANAPC4_WD40

EML5 WDR35

2.59e-0320712PF12894
DomainActinin_actin-bd_CS

FLNA UTRN

3.42e-0323712IPR001589
DomainACTININ_2

FLNA UTRN

3.42e-0323712PS00020
DomainACTININ_1

FLNA UTRN

3.42e-0323712PS00019
Domain-

CELSR1 CELSR3 CELSR2

5.68e-03957132.60.120.200
DomainASX_HYDROXYL

CELSR1 CELSR3 CELSR2

6.54e-03100713PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

CELSR1 CELSR3 CELSR2

7.68e-03106713IPR000152
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

AKT3 AKT1 FOXO4

7.37e-0610573M27095
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_NUCLEUS

AKT3 AKT1 FOXO4

7.37e-0610573MM14778
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

AKT3 AKT1 FOXO4

1.34e-0512573MM15657
PathwayREACTOME_REGULATION_OF_LOCALIZATION_OF_FOXO_TRANSCRIPTION_FACTORS

AKT3 AKT1 FOXO4

1.34e-0512573M27939
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

AKT3 AKT1 ZNF385A

2.21e-0514573MM15341
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS

AKT3 AKT1 ZNF385A

2.21e-0514573M27638
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

AKT3 AKT1 FOXO4

9.14e-0522573MM15656
PathwayREACTOME_CONSTITUTIVE_SIGNALING_BY_AKT1_E17K_IN_CANCER

AKT3 AKT1 FOXO4

1.53e-0426573M27558
PathwayKEGG_MEDICUS_VARIANT_LOSS_OF_NKX3_1_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.59e-045572M48999
PathwayWP_LIPID_METABOLISM_PATHWAY

AKT3 ACLY AKT1

2.13e-0429573M39762
PathwayPID_S1P_S1P3_PATHWAY

AKT3 GNA14 AKT1

2.13e-0429573M55
PathwayKEGG_MEDICUS_REFERENCE_MAGI_PTEN_SIGNALING_PATHWAY

AKT3 AKT1

2.38e-046572M47523
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PI3K_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

3.33e-047572M47407
PathwayKEGG_MEDICUS_REFERENCE_ACH_CHRN_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

3.33e-047572M47790
PathwayPID_PI3KCI_AKT_PATHWAY

AKT3 AKT1 FOXO4

3.74e-0435573M249
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47399
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47394
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47395
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47404
PathwayKEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47405
PathwayKEGG_MEDICUS_REFERENCE_P4_PR_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47803
PathwayREACTOME_RUNX2_REGULATES_GENES_INVOLVED_IN_CELL_MIGRATION

AKT3 AKT1

4.43e-048572M27806
PathwayKEGG_MEDICUS_VARIANT_TGFA_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47482
PathwayKEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47498
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_RET_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

4.43e-048572M47715
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47397
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47392
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47391
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47402
PathwayKEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47802
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_MET_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47490
PathwayKEGG_MEDICUS_REFERENCE_TGFA_EGFR_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47481
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

AKT3 AKT1

5.68e-049572MM15666
PathwayKEGG_MEDICUS_REFERENCE_ICOSLG_ICOS_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

5.68e-049572M47972
PathwayKEGG_MEDICUS_VARIANT_EGFR_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

7.08e-0410572M47400
PathwayKEGG_MEDICUS_REFERENCE_HGF_MET_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

7.08e-0410572M47401
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CD28_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

7.08e-0410572M47615
PathwayKEGG_MEDICUS_ENV_FACTOR_NICOTINE_NNK_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

8.63e-0411572M47797
PathwayKEGG_MEDICUS_REFERENCE_KITLG_KIT_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

8.63e-0411572M47403
PathwayKEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

8.63e-0411572M47406
PathwayKEGG_MEDICUS_REFERENCE_IGF2_IGF1R_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

8.63e-0411572M47484
PathwayKEGG_MEDICUS_REFERENCE_EREG_EGFR_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

8.63e-0411572M47499
PathwayKEGG_MEDICUS_REFERENCE_NRG_ERBB4_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

8.63e-0411572M47756
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01339

AKT3 AKT1

8.63e-0411572M47791
PathwayKEGG_MEDICUS_REFERENCE_AREG_EGFR_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

8.63e-0411572M47501
PathwayKEGG_MEDICUS_VARIANT_ERBB2_OVEREXPRESSION_TO_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.03e-0312572M47393
PathwayKEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_PI3K_SIGNALING_PATHWAY_N01350

AKT3 AKT1

1.03e-0312572M47798
PathwayKEGG_MEDICUS_REFERENCE_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY

AKT3 AKT1

1.03e-0312572M47558
PathwayKEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNAI_PI3K_BAD_SIGNALING_PATHWAY

AKT3 AKT1

1.03e-0312572M47559
PathwayREACTOME_SARS_COV_2_TARGETS_HOST_INTRACELLULAR_SIGNALLING_AND_REGULATORY_PATHWAYS

AKT3 AKT1

1.03e-0312572M45022
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

AKT3 AKT1

1.03e-0312572MM14777
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

AKT3 AKT1

1.03e-0312572MM14550
PathwayWP_OSTEOARTHRITIC_CHONDROCYTE_HYPERTROPHY

JUND AKT3 AKT1

1.07e-0350573M48087
PathwayKEGG_MEDICUS_REFERENCE_PDGF_PDGFR_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.22e-0313572M47398
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGF1R_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.22e-0313572M47603
PathwayREACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING

AKT3 AKT1

1.22e-0313572M549
PathwayWP_FEMALE_STEROID_HORMONES_IN_CARDIOMYOCYTE_ENERGY_METABOLISM

ACLY ESRRA

1.42e-0314572M48059
PathwayKEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.42e-0314572M47390
PathwayKEGG_MEDICUS_REFERENCE_IGF_IGFR_PI3K_NFKB_SIGNALING_PATHWAY

AKT3 AKT1

1.42e-0314572M47467
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_PI3K_NFKB_SIGNALING_PATHWAY

AKT3 AKT1

1.42e-0314572M47536
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

AKT3 AKT1

1.42e-0314572M3862
PathwayKEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.63e-0315572M47389
PathwayKEGG_MEDICUS_REFERENCE_RELN_VLDLR_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.63e-0315572M47663
PathwayREACTOME_ACTIVATION_OF_BAD_AND_TRANSLOCATION_TO_MITOCHONDRIA

AKT3 AKT1

1.63e-0315572M26902
PathwayBIOCARTA_BCELLSURVIVAL_PATHWAY

JUND AKT1

1.63e-0315572M4835
PathwayKEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.63e-0315572M47475
PathwayWP_RIOK1_AND_RIOK2_IN_EGFR_AND_PI3KMEDIATED_TUMORIGENESIS

AKT3 AKT1

1.63e-0315572M48306
PathwayKEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY

AKT3 AKT1

1.63e-0315572M47971
PathwayWP_INVOLVEMENT_OF_SECRETASE_IN_NEURODEGENERATIVE_DISEASES

AKT3 AKT1

2.10e-0317572M48086
PathwayBIOCARTA_BCELLSURVIVAL_PATHWAY

JUND AKT1

2.10e-0317572MM1353
PathwaySA_PTEN_PATHWAY

AKT3 AKT1

2.10e-0317572M12771
PathwaySA_TRKA_RECEPTOR

AKT3 AKT1

2.10e-0317572M18895
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION

AKT3 AKT1 FOXO4

2.39e-0366573M27938
PathwayWP_TGFBETA_SIGNALING_IN_THYROID_CELLS_FOR_EPITHELIALMESENCHYMAL_TRANSITION

AKT3 AKT1

2.63e-0319572M39370
PathwayKEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY

AKT3 AKT1

2.63e-0319572M47525
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS

AKT3 AKT1

3.21e-0321572M14966
PathwayBIOCARTA_RAS_PATHWAY

AKT1 FOXO4

3.21e-0321572MM1464
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

AKT3 AKT1

3.21e-0321572M5876
PathwayREACTOME_CTLA4_INHIBITORY_SIGNALING

AKT3 AKT1

3.21e-0321572MM14996
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

AKT3 AKT1

3.52e-0322572M13897
PathwayBIOCARTA_AKT_PATHWAY

AKT1 FOXO4

3.52e-0322572M15258
PathwayBIOCARTA_RAS_PATHWAY

AKT1 FOXO4

3.52e-0322572M17294
PathwayKEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY

AKT3 AKT1

3.52e-0322572M47919
PathwayWP_PROLACTIN_SIGNALING

FLNA AKT1 CTSD

3.58e-0376573M39601
PathwayWP_SIGNAL_TRANSDUCTION_OF_S1P_RECEPTOR

AKT3 AKT1

3.85e-0323572MM15952
PathwayWP_SILDENAFIL_TREATMENT

AKT3 AKT1

3.85e-0323572M46455
PathwayREACTOME_CD28_DEPENDENT_PI3K_AKT_SIGNALING

AKT3 AKT1

3.85e-0323572MM14993
PathwayWP_MAPK_SIGNALING_PATHWAY

FLNA JUND AKT3 AKT1

3.96e-03160574MM15990
PathwayREACTOME_ESTROGEN_DEPENDENT_NUCLEAR_EVENTS_DOWNSTREAM_OF_ESR_MEMBRANE_SIGNALING

AKT3 AKT1

4.19e-0324572M27952
PathwayKEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY

AKT3 AKT1

4.19e-0324572M47460
Pubmed

The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.

CELSR1 CELSR3 CELSR2

8.87e-09373311677057
Pubmed

The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.

CELSR1 CELSR3 CELSR2

3.54e-08473337224017
Pubmed

Developmental expression profiles of Celsr (Flamingo) genes in the mouse.

CELSR1 CELSR3 CELSR2

3.54e-08473311850187
Pubmed

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

AKT3 ACLY AKT1

1.77e-07673331996678
Pubmed

Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.

CELSR1 CELSR3 CELSR2

3.09e-07773317937400
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

FNBP1 FLNA JUND RIF1 ABCF1 ACLY CARMIL1 ESRRA GTSE1 DNMBP VDAC1

6.27e-07774731115302935
Pubmed

A dual role for planar cell polarity genes in ciliated cells.

CELSR1 CELSR3 CELSR2

1.45e-061173325024228
Pubmed

Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.

CELSR1 CELSR3 CELSR2

1.93e-061273311891983
Pubmed

Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.

CELSR1 CELSR3 CELSR2

1.93e-061273320631168
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA JUND CELSR1 CELSR3 CELSR2 RASA3 GTSE1 AKT1 TNFAIP2 DNMBP ELAC2 MYORG

3.07e-061105731235748872
Pubmed

Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex.

CELSR1 CELSR3 CELSR2

3.18e-061473339225402
Pubmed

High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.

FLNA RIF1 MRTFB UTRN

3.82e-065073429560723
Pubmed

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus.

CELSR1 CELSR3 CELSR2

3.96e-061573320473291
Pubmed

Neuroprotective Properties of Kempferol Derivatives from Maesa membranacea against Oxidative Stress-Induced Cell Damage: An Association with Cathepsin D Inhibition and PI3K/Akt Activation.

AKT1 CTSD

4.35e-06273234638702
Pubmed

Direct control of the Forkhead transcription factor AFX by protein kinase B.

AKT1 FOXO4

4.35e-06273210217147
Pubmed

Regulation of the Forkhead transcription factor AFX by Ral-dependent phosphorylation of threonines 447 and 451.

AKT1 FOXO4

4.35e-06273211689711
Pubmed

Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on chromosome 9.

CELSR3 CELSR2

4.35e-06273210790539
Pubmed

Rarity of AKT1 and AKT3 E17K mutations in squamous cell carcinoma of lung.

AKT3 AKT1

4.35e-06273220980808
Pubmed

Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.

CELSR1 CELSR2

4.35e-06273223292348
Pubmed

AKT signaling pathway activated by HIN-1 methylation in non-small cell lung cancer.

SCGB3A1 AKT1

4.35e-06273222095135
Pubmed

Impaired Spatial Learning is Associated with Disrupted Integrity of the White Matter in Akt3 Knockout Mice.

AKT3 AKT1

4.35e-06273227671373
Pubmed

AKT isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans.

AKT3 AKT1

4.35e-06273223303682
Pubmed

Myogenic Akt signaling upregulates the utrophin-glycoprotein complex and promotes sarcolemma stability in muscular dystrophy.

AKT1 UTRN

4.35e-06273218986978
Pubmed

Akt3 deletion in mice impairs spatial cognition and hippocampal CA1 long long-term potentiation through downregulation of mTOR.

AKT3 AKT1

4.35e-06273230053339
Pubmed

Distinct functional roles of Akt isoforms for proliferation, survival, migration and EGF-mediated signalling in lung cancer derived disseminated tumor cells.

AKT3 AKT1

4.35e-06273221777670
Pubmed

Regulation of intracellular localization and transcriptional activity of FOXO4 by protein kinase B through phosphorylation at the motif sites conserved among the FOXO family.

AKT1 FOXO4

4.35e-06273216272144
Pubmed

Akt1 and akt3 exert opposing roles in the regulation of vascular tumor growth.

AKT3 AKT1

4.35e-06273225388284
Pubmed

An inventory of the human ABC proteins.

ABCF1 ABCF2

4.35e-06273210581359
Pubmed

A genome-wide RNAi screen identifies FOXO4 as a metastasis-suppressor through counteracting PI3K/AKT signal pathway in prostate cancer.

AKT1 FOXO4

4.35e-06273224983969
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DNHD1 FLNA RIF1 CDSN TBRG4 ABCF1 ACAT1 ACLY ABCF2 PNPLA8 KRR1 CTSD VDAC1

7.58e-061425731330948266
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

DNHD1 FLNA ARL3 EML5 ACAT1 ACLY SCN10A CTSD CCDC180 UTRN VDAC1

8.52e-061016731119056867
Pubmed

Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.

AKT3 AKT1

1.30e-05373219805051
Pubmed

Deletion of PKBalpha/Akt1 affects thymic development.

AKT3 AKT1

1.30e-05373217912369
Pubmed

Differential activation of AKT isoforms by growth factors in human myotubes.

AKT3 AKT1

1.30e-05373237879895
Pubmed

Signalling specificity in the Akt pathway in breast cancer.

AKT3 AKT1

1.30e-05373225233414
Pubmed

Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation.

AKT3 AKT1

1.30e-05373221555366
Pubmed

Specific Akt Family Members Impair Stress-Mediated Transactivation of Viral Promoters and Enhance Neuronal Differentiation: Important Functions for Maintaining Latency.

AKT3 AKT1

1.30e-05373232796067
Pubmed

All Akt isoforms (Akt1, Akt2, Akt3) are involved in normal hearing, but only Akt2 and Akt3 are involved in auditory hair cell survival in the mammalian inner ear.

AKT3 AKT1

1.30e-05373225811375
Pubmed

Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development.

AKT3 AKT1

1.30e-05373220724596
Pubmed

Differential prognostic values of the three AKT isoforms in acute myeloid leukemia.

AKT3 AKT1

1.30e-05373238528080
Pubmed

Akt Regulates Axon Wrapping and Myelin Sheath Thickness in the PNS.

AKT3 AKT1

1.30e-05373227098694
Pubmed

Increased level of phosphorylated akt measured by chemiluminescence-linked immunosorbent assay is a predictor of poor prognosis in primary breast cancer overexpressing ErbB-2.

AKT3 AKT1

1.30e-05373215987444
Pubmed

Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action.

AKT3 AKT1

1.30e-05373227076519
Pubmed

Role of Akt isoforms in IGF-I-mediated signaling and survival in myoblasts.

AKT3 AKT1

1.30e-05373219703413
Pubmed

MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells.

AKT3 AKT1

1.30e-05373219825827
Pubmed

Kinetic mechanism of AKT/PKB enzyme family.

AKT3 AKT1

1.30e-05373216540465
Pubmed

Enhanced lipid biosynthesis in oral squamous cell carcinoma cancer-associated fibroblasts contributes to tumor progression: Role of IL8/AKT/p-ACLY axis.

ACLY AKT1

1.30e-05373238494608
Pubmed

Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in mice.

AKT3 AKT1

1.30e-05373222632897
Pubmed

Variation in Akt protein kinases in human populations.

AKT3 AKT1

1.30e-05373228931550
Pubmed

Molecular alterations in AKT1, AKT2 and AKT3 detected in breast and prostatic cancer by FISH.

AKT3 AKT1

1.30e-05373220102399
Pubmed

Cellular survival: a play in three Akts.

AKT3 AKT1

1.30e-05373210579998
Pubmed

Key signalling nodes in mammary gland development and cancer. Signalling downstream of PI3 kinase in mammary epithelium: a play in 3 Akts.

AKT3 AKT1

1.30e-05373220398329
Pubmed

Distinct roles of the three Akt isoforms in lactogenic differentiation and involution.

AKT3 AKT1

1.30e-05373218561256
Pubmed

Differential effects of Akt isoforms on somatic cell reprogramming.

AKT3 AKT1

1.30e-05373225037569
Pubmed

All Three AKT Isoforms Can Upregulate Oxygen Metabolism and Lactate Production in Human Hepatocellular Carcinoma Cell Lines.

AKT3 AKT1

1.30e-05373238396845
Pubmed

Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders.

AKT3 AKT1

1.30e-05373233325370
Pubmed

AKT isoforms have distinct hippocampal expression and roles in synaptic plasticity.

AKT3 AKT1

1.30e-05373229173281
Pubmed

Akt/PKB isoforms expression in the human lumbar herniated disc: correlation with clinical and MRI findings.

AKT3 AKT1

1.30e-05373221590431
Pubmed

Protein kinase Akt activity in human thyroid tumors.

AKT3 AKT1

1.30e-05373229235817
Pubmed

Immunohistological Examination of AKT Isoforms in the Brain: Cell-Type Specificity That May Underlie AKT's Role in Complex Brain Disorders and Neurological Disease.

AKT3 AKT1

1.30e-05373234296180
Pubmed

The Akt isoforms are present at distinct subcellular locations.

AKT3 AKT1

1.30e-05373220018949
Pubmed

Identification of AKT kinases as unfavorable prognostic factors for hepatocellular carcinoma by a combination of expression profile, interaction network analysis and clinical validation.

AKT3 AKT1

1.30e-05373224247267
Pubmed

Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.

AKT3 AKT1

1.30e-05373217982014
Pubmed

Dissociation of gemcitabine sensitivity and protein kinase B signaling in pancreatic ductal adenocarcinoma models.

AKT3 AKT1

1.30e-05373217895832
Pubmed

Opposing functions of Akt isoforms in lung tumor initiation and progression.

AKT3 AKT1

1.30e-05373224722238
Pubmed

Caspase-3-mediated cleavage of Akt: involvement of non-consensus sites and influence of phosphorylation.

AKT3 AKT1

1.30e-05373217544405
Pubmed

The AKT genes and their roles in various disorders.

AKT3 AKT1

1.30e-05373224039187
Pubmed

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3.

AKT3 AKT1

1.30e-05373210491192
Pubmed

Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies.

AKT3 AKT1

1.30e-05373216923958
Pubmed

Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death.

AKT3 AKT1

1.30e-05373217202487
Pubmed

Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer.

AKT3 AKT1

1.30e-05373226953242
Pubmed

Gene variants in AKT1, GCKR and SOCS3 are differentially associated with metabolic traits in Mexican Amerindians and Mestizos.

AKT1 GCKR

1.30e-05373230176313
Pubmed

Akt1 ablation inhibits, whereas Akt2 ablation accelerates, the development of mammary adenocarcinomas in mouse mammary tumor virus (MMTV)-ErbB2/neu and MMTV-polyoma middle T transgenic mice.

AKT3 AKT1

1.30e-05373217210696
Pubmed

Role for Akt3/protein kinase Bgamma in attainment of normal brain size.

AKT3 AKT1

1.30e-05373215713641
Pubmed

GTSE1 Facilitates the Malignant Phenotype of Lung Cancer Cells via Activating AKT/mTOR Signaling.

GTSE1 AKT1

1.30e-05373234007784
Pubmed

Identification and quantification of AKT isoforms and phosphoforms in breast cancer using a novel nanofluidic immunoassay.

AKT3 AKT1

1.30e-05373223929892
Pubmed

Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos.

CELSR1 CELSR3 CELSR2

2.23e-052673337228654
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNA RIF1 CDSN ABCF1 RASA3 ACAT1 ACLY ABCF2 KRR1 CTSD UTRN ELAC2

2.34e-051353731229467282
Pubmed

AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.

AKT1 FOXO4

2.60e-05473221884932
Pubmed

Photoreceptor Neuroprotection: Regulation of Akt Activation Through Serine/Threonine Phosphatases, PHLPP and PHLPPL.

AKT3 AKT1

2.60e-05473226427440
Pubmed

Protein kinase Akt2/PKBβ is involved in blastomere proliferation of preimplantation mouse embryos.

AKT3 AKT1

2.60e-05473231552693
Pubmed

Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism.

AKT3 AKT1

2.60e-05473219435822
Pubmed

Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.

AKT3 AKT1

2.60e-05473221507933
Pubmed

Cytoplasmic Endonuclease G promotes nonalcoholic fatty liver disease via mTORC2-AKT-ACLY and endoplasmic reticulum stress.

ACLY AKT1

2.60e-05473237794041
Pubmed

Mitochondria-associated endoplasmic reticulum membrane (MAM) integrity is required for insulin signaling and is implicated in hepatic insulin resistance.

AKT1 VDAC1

2.60e-05473224947355
Pubmed

Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.

AKT3 AKT1

2.60e-05473219933838
Pubmed

S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt.

AKT3 AKT1

2.60e-05473221906027
Pubmed

Conditional inactivation of Akt three isoforms causes tau hyperphosphorylation in the brain.

AKT3 AKT1

2.60e-05473226227811
Pubmed

Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.

AKT3 AKT1

2.60e-05473217942896
Pubmed

Akt1 deletion prevents lung tumorigenesis by mutant K-ras.

AKT3 AKT1

2.60e-05473221242979
Pubmed

Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice.

AKT3 AKT1

2.60e-05473230567482
Pubmed

Human immunodeficiency virus type 1 induces lytic cycle replication of Kaposi's-sarcoma-associated herpesvirus: role of Ras/c-Raf/MEK1/2, PI3K/AKT, and NF-κB signaling pathways.

AKT3 AKT1

2.60e-05473221763505
Pubmed

GLUT5 regulation by AKT1/3-miR-125b-5p downregulation induces migratory activity and drug resistance in TLR-modified colorectal cancer cells.

AKT3 AKT1

2.60e-05473232649737
Pubmed

Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX.

AKT1 FOXO4

2.60e-05473211313479
Pubmed

Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.

CELSR2 ACAT1 GCKR

3.12e-052973320167577
Pubmed

Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.

CELSR1 CELSR3 CELSR2

4.21e-053273323177622
Pubmed

Leptin deficiency and beta-cell dysfunction underlie type 2 diabetes in compound Akt knockout mice.

AKT3 AKT1

4.33e-05573219289493
Pubmed

The E3 ligase TTC3 facilitates ubiquitination and degradation of phosphorylated Akt.

AKT3 AKT1

4.33e-05573220059950
Pubmed

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

AKT3 AKT1

4.33e-0557329512493
Pubmed

Platelet-derived growth factor protects neurons against gp120-mediated toxicity.

AKT3 AKT1

4.33e-05573218300076
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR3 CELSR2

1.08e-083413913
GeneFamilyAdhesion G protein-coupled receptors, subfamily C|CELSR cadherins

CELSR1 CELSR3 CELSR2

1.08e-0834131189
GeneFamilyATP binding cassette subfamily F

ABCF1 ABCF2

1.50e-053412810
GeneFamilySolute carriers

SLC22A16 SLC9B2 SLC35C2 SLC6A5 SLCO3A1 SLC2A11

2.46e-04395416752
CoexpressionGSE11961_UNSTIM_VS_ANTI_IGM_AND_CD40_STIM_6H_FOLLICULAR_BCELL_DN

CELSR1 SLC9B2 SLCO3A1 HOOK2 RGS12 MYORG

2.04e-05200736M9335
CoexpressionGSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_DN

JUND TNFAIP2 HOOK2 PARP14 ELAC2 MYORG

2.04e-05200736M9028
ToppCellcontrol|World / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

JUND NLRP1 TNFAIP2 HOOK2 ZNF385A KDM5D

3.81e-07171736837c1186504f110ccf5b580d9cd4e50ca60c173f
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 EML5 GUK1 ACLY AKT1

7.73e-07193736fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|COVID-19_Mild / Disease condition and Cell class

JUND SLCO3A1 TNFAIP2 ZNF385A PARP14 CTSD

8.45e-071967363729d1444c65cad640377894decc64129bc3fd5b
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 EML5 CELSR2 ACLY

8.13e-06167735b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 CELSR1 EML5 HOOK2 UTRN

1.37e-051867354e94158db52df41d71e67b02b9895a358eebee0f
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JUND TOPAZ1 SCN10A TNFAIP2 CTSD

1.37e-0518673523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 EML5 GUK1 ACLY

1.63e-05193735471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCelldroplet-Pancreas-Endocrine-21m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 EML5 GUK1 ACLY

1.68e-051947353a3ecedcdc7691cf21775818b598208fcb980c29
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 EML5 GUK1 ACLY

1.68e-051947350b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellPBMC-Control-cDC_0|Control / Compartment, Disease Groups and Clusters

FLNA SLCO3A1 NLRP1 TNFAIP2 CTSD

1.89e-05199735ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MAGED1 GNA14 CELSR2 NRIP3 SLC2A11

1.89e-05199735eb5971660dff356721a004f821d52a5b7a33c951
ToppCellCOVID-19-COVID-19_Mild|COVID-19 / Disease, condition lineage and cell class

JUND TNFAIP2 ZNF385A PARP14 UTRN

1.94e-0520073562c25042086f1afd1102e0720e933c2e476468fd
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 EML5 LRRIQ4 CCDC180

3.47e-05112734456278fb92dd41820fde8cf27c68fec45e15f972
ToppCellVE-CD4-CD8_1|VE / Condition, Cell_class and T cell subcluster

DNHD1 DNMBP RGS12 MYORG

5.00e-05123734bc0f509716bb71d6e3fa343f4920ecb80eb62794
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR1 FOXO4 BCL11A CCDC180

1.29e-04157734d12f343454202da86a06d0369f8ffe5662cd091b
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MRTFB GNA14 GTSE1 NRIP3

1.45e-041627341f1b93394b1f27cbb76b369c19b9313609edd577
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 ACLY KDM5D

1.60e-0416673466026988509e39e41274fa0de738383219e8ff30
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

SIGLEC10 CTSD UTRN RGS12

1.67e-04168734bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC35C2 TNFAIP2 NRIP3 CTSD

1.67e-04168734a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCGB3A1 MAGED1 HOOK2 ITIH6

1.71e-04169734db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCellCOVID-19_Mild-PLT_2|World / Disease Group and Platelet Clusters

DNHD1 TOPAZ1 GTSE1 KDM5D

1.71e-041697346abfdc8b437f19c03b408bedc245059d28c6ba6a
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCGB3A1 MAGED1 HOOK2 ITIH6

1.71e-0416973497b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCGB3A1 MAGED1 HOOK2 ITIH6

1.71e-041697341a684471dbda42e1470e5a889648666e14f25982
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM44 CELSR3 GTSE1 TNFAIP2

1.79e-04171734845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

FLNA MRTFB CARMIL1 UTRN

1.79e-04171734e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellCOVID-19_Mild-PLT_2|COVID-19_Mild / Disease Group and Platelet Clusters

DNHD1 TOPAZ1 GTSE1 KDM5D

1.87e-04173734d11705e56b6b21eec963ea224717f27680c781ed
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC166 FAAP24 GTSE1 NRIP3

1.87e-04173734766e712e4db440468a32971459c1d3354add611f
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC166 FAAP24 GTSE1 NRIP3

1.87e-0417373440ef91afb366e87b5ba2951d2578ebfe04d042c0
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SCGB3A1 CELSR1 DNAJC16 DNMBP

1.91e-04174734e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GTSE1 NLRP1 TNFAIP2 CTSD

1.91e-0417473465147b0f8c2ccadd5685430d31081520c157536a
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

SCGB3A1 MAGED1 SLCO3A1 TNFAIP2

1.91e-04174734ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell(03)_Secretory|World / shred by cell type and Timepoint

SCGB3A1 MAGED1 TNFAIP2 NRIP3

2.00e-04176734cb7b1945788196ca79007f0768b6576ec885a0e5
ToppCell5'-Adult-Appendix-Hematopoietic-T_cells-CX3CR1+_CD8_Tmem|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA RASA3 CFAP61 UTRN

2.00e-041767346b06da40eb97ea2db09f3a769494738b3e5fe3fa
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCGB3A1 PRR5L SLC9B2 UTRN

2.04e-04177734227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCGB3A1 PRR5L SLC9B2 UTRN

2.04e-0417773466ffa279147961080c104242a08b176e301d80e3
ToppCellkidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCGB3A1 PRR5L SLC9B2 UTRN

2.04e-041777340cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 CELSR1 CARMIL1 UTRN

2.04e-041777349af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC166 TBRG4 GTSE1 BCL11A

2.08e-041787345ac5257d88fa0dc67714881d6f005f6cea925710
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

JUND MRTFB CELSR3 BCL11A

2.13e-04179734a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCGB3A1 MRTFB KDM5D UTRN

2.22e-041817344ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

RIF1 TNFAIP2 PARP14 UTRN

2.32e-041837348f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 CELSR1 EML5 HOOK2

2.36e-041847347cc5796557379c3d1db078c1aeda40659c6e401c
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA PNPLA8 TNFAIP2 NRIP3

2.41e-0418573442690b95e2e7d56c822211bb1150acb787cfe2e8
ToppCellnormal-na-Lymphocytic_NK-NK_dim-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

PRR5L KDM5D CTSD UTRN

2.41e-04185734b1a8a8c4d0fc7605eabc17dcb6bd9e8ab4fd578c
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell-B_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 JUND BCL11A PARP14

2.46e-041867341a1e5d85a5ad90afee234c12a9b54a5e93a8a2f2
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_B-B_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FNBP1 JUND BCL11A PARP14

2.46e-04186734f1366638edaecad5cad6367440f4c693513bed7e
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND CELSR1 CELSR2 AKT1

2.46e-04186734bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 CELSR1 CARMIL1 UTRN

2.46e-041867343aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ACAT1 CARMIL1 CTSD VDAC1

2.46e-04186734c2b65b8345487710704c3eb043e9bef2e2b1ff27
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

CARMIL1 BCL11A PARP14 DNMBP

2.51e-04187734af1327559f7e01bec070881cae52834917c3da65
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SCGB3A1 MRTFB TNFAIP2 UTRN

2.57e-0418873450b27fc12347ca16bd62333baf345c83cb422a8f
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 EML5 ACLY

2.57e-04188734a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 GUK1 ACLY

2.57e-0418873463773854bf8430fb8229edb385b953a89833d08c
ToppCellfacs-Skin-nan-18m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND GNA14 RASA3 SLCO3A1

2.62e-041897346c71e81373cb7822de23c193a6350b6df9f567bc
ToppCellHSPCs-Ery_prog.|HSPCs / Lineage and Cell class

JUND GNA14 TNFAIP2 BCL11A

2.62e-0418973437d2c45debed1564a40a1085b8b310c50923b9e7
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLNA JUND TNFAIP2 UTRN

2.62e-0418973455aba1ebc012006a5db3ff9c92589cb3d9f7c68a
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FLNA TNFAIP2 ZNF385A CTSD

2.67e-0419073400ef6ec71353e42260c0d807d7da65b63154c288
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FLNA TNFAIP2 ZNF385A CTSD

2.67e-0419073418c020ca9a23399214133ec255ab870e0060f2e1
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

CARMIL1 BCL11A PARP14 DNMBP

2.67e-041907341e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

FLNA PNPLA8 TNFAIP2 CTSD

2.72e-041917347bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SIGLEC10 PNPLA8 TNFAIP2 NRIP3

2.72e-041917340b296404ebad0aadb75737f8c0462ec6934fc8bb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

JUND WDR35 ABCF2 DNMBP

2.72e-041917341ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FNBP1 JUND LRRC69 SLCO3A1

2.78e-04192734930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FNBP1 JUND LRRC69 SLCO3A1

2.78e-04192734c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCelldroplet-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JUND MAGED1 GUK1 ACLY

2.78e-041927340dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RASA3 SLCO3A1 TNFAIP2 NRIP3

2.78e-04192734df1545670370fb1010c567cd059c2783eab315f7
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JUND CARMIL1 BCL11A PARP14

2.89e-04194734ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FNBP1 JUND LRRC69 SLCO3A1

2.89e-041947343211d89440a6f4a9b3d4cfb755890816944242ec
ToppCell(0)_Myeloid-(00)_Monocyte-(001)_CD16+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

SCGB3A1 PRR5L SIGLEC10 UTRN

2.89e-0419473489cb262e04d7105012e957e0add44c73de6c1ed0
ToppCellPBMC-Severe-cDC_5|Severe / Compartment, Disease Groups and Clusters

JUND AKT1 ZNF385A NRIP3

2.89e-04194734b903e23eb75733ca516770727097fe74a9f8c1d1
ToppCellCOVID-19_Severe-Non-classical_Monocyte-|COVID-19_Severe / Disease condition and Cell class

SCGB3A1 SIGLEC10 UTRN RGS12

2.89e-04194734d70b9039fd2fef3e4be086513b94fb7e9bc1f670
ToppCell(0)_Myeloid-(001)_CD16+_Monocyte|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

SCGB3A1 PRR5L SIGLEC10 UTRN

2.89e-041947344240d0b3cf264f51dcf0cb4d0a18641d85d38638
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / Disease condition and Cell class

SCGB3A1 SIGLEC10 UTRN RGS12

2.89e-041947345151546812678ae85cb22224084d27b29e3c4724
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FLNA JUND ZNF385A CTSD

2.95e-04195734ae98215b7b7f22f1aca690920ce6092dc4a3c7db
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WDR35 BCL11A PARP14 DNMBP

2.95e-04195734481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

WDR35 BCL11A PARP14 DNMBP

2.95e-041957346108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FLNA JUND ZNF385A CTSD

2.95e-041957346fcab7aa4db958ccad0300adea9aaae52ace5bff
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

FLNA JUND TNFAIP2 CTSD

2.95e-041957340fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

RASA3 SLCO3A1 NLRP1 TNFAIP2

2.95e-041957345562665dd3beb70e2358aa32611a337bef5731c1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIF1 MAGED1 ACLY KDM5D

2.95e-041957343e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIF1 MAGED1 ACLY KDM5D

2.95e-041957347796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellsevere_COVID-19-Non-classical_Monocyte|severe_COVID-19 / disease group, cell group and cell class (v2)

SCGB3A1 SIGLEC10 ZNF385A RGS12

3.01e-0419673434c1c74cad5e23196e86cfd6f19c836fe57b2264
ToppCellCOVID-19_Moderate-Non-classical_Monocyte|COVID-19_Moderate / disease group, cell group and cell class

SCGB3A1 SIGLEC10 TNFAIP2 RGS12

3.01e-04196734256c557fa11414c9d2cbb1fcff33f482ee1c78ac
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / disease group, cell group and cell class

SCGB3A1 SIGLEC10 TNFAIP2 RGS12

3.01e-04196734af9e8f5ef9d03862f707e105857309b55595b1b9
ToppCellmyeloid-CD14+_Monocyte|World / Lineage and Cell class

JUND TNFAIP2 ZNF385A CTSD

3.01e-04196734b70f9402a1707671c0dd44226fa2adfc4bde8283
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JUND SIGLEC10 PNPLA8 NRIP3

3.01e-0419673401cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCellmyeloid|World / Lineage and Cell class

JUND TNFAIP2 ZNF385A CTSD

3.01e-04196734c76af19827917b9f64ed9fff449f34d04e080a2a
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA RASA3 ZNF385A VDAC1

3.01e-0419673480264c2fbd94418f981085fed7c5bdda1e6f404c
ToppCellControl-Non-classical_Monocyte-|Control / Disease condition and Cell class

SCGB3A1 PRR5L SIGLEC10 UTRN

3.01e-04196734b17ab094cdc7050c2997e24ed474779b5d6f6146
ToppCellControl-Non-classical_Monocyte|Control / Disease condition and Cell class

SCGB3A1 PRR5L SIGLEC10 UTRN

3.01e-04196734404064ccfe2cb73df7a7f88aa65d86b97dcef9d4
ToppCellCOVID-19_Severe-Myeloid-Non-classical_Monocyte|COVID-19_Severe / Disease group, lineage and cell class

SCGB3A1 SIGLEC10 TNFAIP2 RGS12

3.06e-04197734c5837b9a5a39a0f607a4e217ade9fc87d82a5406
ToppCell343B-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNA MRTFB GNA14 DNMBP

3.06e-04197734ec92d60f802c9d4bdf9877bed5c0a91a5a5ed5d0
ToppCell343B-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

FLNA MRTFB GNA14 DNMBP

3.06e-041977347bec9c1bc8851064eb229324493b47a31201c83c
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB3A1 SIGLEC10 TNFAIP2 RGS12

3.12e-041987349b8679b3dd8f4220d71f607b7080cb88d6e71129
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB3A1 SIGLEC10 TNFAIP2 RGS12

3.12e-041987348b6b602ebe59b6dca6a22f17385d3160ff3ac67e
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-classical_monocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FLNA TNFAIP2 ZNF385A CTSD

3.12e-0419873474591eba5dbb2d77d416309326a26be969e4ad42
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GNA14 NLRP1 PARP14 UTRN

3.12e-04198734b027a141ab531d0f5d6a26811a53427e7b0771dd
ToppCell(0)_Myeloid-(00)_Monocyte|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)

FLNA JUND TNFAIP2 CTSD

3.12e-041987349c17589ef0f6583c4c106c06936877fd74c258ce
ToppCellPBMC-Severe-Myeloid-Non-classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SCGB3A1 SIGLEC10 TNFAIP2 RGS12

3.12e-04198734b9030390316baf456135f85f831394e1e11ecf3e
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(010)_cDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

FLNA TNFAIP2 ZNF385A VDAC1

3.12e-041987344abc274edac40f8836255fac2371ffd98a32cccd
DrugAmoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A

RIF1 CELSR3 RASA3 ESRRA SLCO3A1 GCKR UTRN SLC2A11

2.26e-071977381513_UP
DrugHippeastrine hydrobromide [22352-41-6]; Down 200; 10uM; PC3; HT_HG-U133A

FNBP1 JUND FAAP24 SLC35C2 BCL11A DNMBP CEP43

3.63e-062007373682_DN
Diseasearachidonic acid measurement

FNBP1 OMA1 SLC22A16

3.08e-0525723EFO_0006808
Diseaseparaplegia (biomarker_via_orthology)

AKT1 FOXO4

5.84e-055722DOID:607 (biomarker_via_orthology)
Diseaseinsulin-like growth factor-binding protein 1 measurement

CELSR2 GCKR

5.84e-055722EFO_0020474
DiseaseCongenital Pain Insensitivity

SCN10A PRDM12

1.22e-047722C0002768
Diseasegroup XIIB secretory phospholipase A2-like protein measurement

CELSR2 GCKR

1.22e-047722EFO_0801657
Diseasefree cholesterol to total lipids in medium VLDL percentage

CELSR2 GCKR RGS12

3.71e-0457723EFO_0022284
Diseasefree cholesterol to total lipids in very large VLDL percentage

CELSR2 GCKR RGS12

4.11e-0459723EFO_0022289
Diseasetriglycerides to total lipids in medium VLDL percentage

CELSR2 GCKR RGS12

4.98e-0463723EFO_0022335
Diseasecholesterol to total lipids in medium VLDL percentage

CELSR2 GCKR RGS12

4.98e-0463723EFO_0022239
Diseasecholesteryl esters to total lipids in medium VLDL percentage

CELSR2 GCKR RGS12

5.22e-0464723EFO_0022253
Diseasecholesterol to total lipids in very small VLDL percentage

CELSR2 GCKR RGS12

5.97e-0467723EFO_0022245
DiseaseHypertriglyceridemia

CELSR2 GCKR

6.04e-0415722C0020557
Diseasecathepsin D measurement

GCKR CTSD

6.04e-0415722EFO_0010611
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

ARL3 AKT1

6.89e-0416722DOID:0110861 (implicated_via_orthology)
DiseasePsychoses, Substance-Induced

HTR6 AKT1

7.80e-0417722C0033941
DiseaseIGF-1 measurement, IGFBP-3 measurement

CELSR2 GCKR

7.80e-0417722EFO_0004626, EFO_0004627
DiseaseEpilepsy, Cryptogenic

FLNA AKT1 VDAC1

1.07e-0382723C0086237
DiseaseAwakening Epilepsy

FLNA AKT1 VDAC1

1.07e-0382723C0751111
DiseaseAura

FLNA AKT1 VDAC1

1.07e-0382723C0236018
Diseaseprostate adenocarcinoma (is_implicated_in)

AKT3 AKT1

1.08e-0320722DOID:2526 (is_implicated_in)
DiseasePsychoses, Drug

HTR6 AKT1

1.20e-0321722C0033937
Diseasemalignant astrocytoma (is_marker_for)

AKT3 AKT1

1.44e-0323722DOID:3069 (is_marker_for)
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

AKT3 AKT1 BCL11A

2.19e-03105723DOID:9352 (implicated_via_orthology)
DiseaseEpilepsy

FLNA AKT1 VDAC1

2.43e-03109723C0014544

Protein segments in the cluster

PeptideGeneStartEntry
LKPGIKLTLSALLDG

VDAC1

251

P21796
SKELPKSLAGGLLPS

ZNF385A

316

Q96PM9
TLGPEAKSLLSGLLK

AKT1

371

P31749
GVGKSTLLLLLTGKL

ABCF1

661

Q8NE71
KSTLLKLLTGELLPT

ABCF2

436

Q9UG63
RKALKASLTLGILLG

HTR6

261

P50406
TLISTHGLPGKKLLD

CFAP61

696

Q8NHU2
LLLGLDNAGKTTLLK

ARL3

21

P36405
LKPLLSLLKVAGREG

DNMBP

1201

Q6XZF7
TGSKKSLDLTGPLLL

CELSR1

1586

Q9NYQ6
GGSKKSLDLTGPLLL

CELSR2

1511

Q9HCU4
PIELLTKGGLLLLSC

DNHD1

761

Q96M86
PLIVDTGGLFLKKLT

CCDC180

201

Q9P1Z9
LLAGLLLPGTLAKSI

CDSN

21

Q15517
LLSGLLIKDPNKRLG

AKT3

376

Q9Y243
KKELGSALLSLLGDL

RBM44

646

Q6ZP01
GSKSLKPDDLGSLRL

RASA3

271

Q14644
SALGKLPGLKTLVLQ

LRRC69

31

Q6ZNQ3
GLTENTGLPRKLLEK

CDRT4

11

Q8N9R6
SLAGILGTTKDTPKL

MAGED1

546

Q9Y5V3
LGTTKDTPKLGLLLV

MAGED1

551

Q9Y5V3
LPSELGSLSKLKILG

LRRIQ4

341

A6NIV6
EGEGTPGLTAKKLLL

HOOK2

226

Q96ED9
GLLASPDLGLLKLAS

JUND

86

P17535
APGKGSDLELLSSLL

KDM5D

1351

Q9BY66
GLSKKLLLGSPSSLS

BCL11A

616

Q9H165
LLLLGGLPSSSKLAT

FOXO4

396

P98177
ADALLGSLLGKTILP

NLRP1

436

Q9C000
ELKTELKLRGLPVSG

MRTFB

396

Q9ULH7
LGSRPIKGKLSKLSL

DNAJC16

746

Q9Y2G8
GPKGSTLKALELLTN

KRR1

166

Q13601
LVLKTGLKAPGLALA

PRDM12

11

Q9H4Q4
LGLKKTLLKAPGSTS

GTSE1

291

Q9NYZ3
GLGALLDVTKLSPEK

OSR1

146

Q8TAX0
KLGDLLLLAQSKLPS

PRR5L

171

Q6MZQ0
KGGSATKILLETLLL

GCKR

261

Q14397
LSRGPLSKSLLEKAG

PARP14

1041

Q460N5
NGGLTSISDLPKLKL

ANP32C

51

O43423
GPLAITLGRKKSLLV

SLC2A11

86

Q9BYW1
GPSGAGKSTLLKRLL

GUK1

11

Q16774
DLKLISDKIGSLGLG

CEP43

316

O95684
SLKRGLSLKLGATPE

FNBP1

386

Q96RU3
SPSLDLSKIKVSGLG

FLNA

966

P21333
LGKKRALLLSEPSLL

FAAP24

146

Q9BTP7
KVSTLPAITLKLGGK

CTSD

331

P07339
LRSTKSGPKLLSGLS

CCDC166

396

P0CW27
GPGILLSKTPKILLS

ITIH6

841

Q6UXX5
LSGTKLSPEPLKALL

CARMIL1

431

Q5VZK9
TLAGRALLSKKGLLS

EML5

1541

Q05BV3
SKKSLDLTGPLLLGG

CELSR3

1661

Q9NYQ7
GGKLVLSSLPKRLCL

ESRRA

66

P11474
LSKLLGSLYALGIPK

TBRG4

146

Q969Z0
ADLLPLDGLKKLGSS

NRIP3

41

Q9NQ35
IGILKLSTSAPKGLT

PNPLA8

81

Q9NP80
LKLLLLGTGESGKST

GNA14

36

O95837
LLDLLEGLTGTSLPK

UTRN

66

P46939
LGIFLGGLLVKKLSL

SLCO3A1

401

Q9UIG8
GGLLVKKLSLSALGA

SLCO3A1

406

Q9UIG8
SLGLKLPVKDLELGT

SLC6A5

781

Q9Y345
KPGSEVLTLLLKSLE

RIF1

521

Q5UIP0
LSGVLTLKLPETLGK

SLC22A16

516

Q86VW1
IIGGKLLGLIKLPTL

SLC9B2

126

Q86UD5
LGSLSLLPATKLGSI

ACAT1

56

P24752
VSPITGRSKLLLLGK

OMA1

216

Q96E52
GASLKLTLLNPKGRI

ACLY

261

P53396
SLGPENLLLKGATLK

ATP11C

241

Q8NB49
TLSLLLGPLGELKSH

TNFAIP2

446

Q03169
LSGLLVRLSGEKEPL

RGS12

1071

O14924
LSGMILTLKETGLPK

ELAC2

121

Q9BQ52
LLELGVAKKGSLSVL

SCN10A

741

Q9Y5Y9
KGLGSSPDLELLLRS

SLC35C2

331

Q9NQQ7
TSLKGLIGPEKLASR

TOPAZ1

1396

Q8N9V7
LGTLKVPGKEISALS

WDR35

296

Q9P2L0
SGSILQLPDKKGLIS

SIGLEC10

531

Q96LC7
LGTLNPLKLLLSSLG

SCGB3A1

51

Q96QR1
SKDLKPLLGSAVLGL

MYORG

51

Q6NSJ0