Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSUZ

ARPP21 R3HDM1

5.70e-053822PF12752
DomainSUZ

ARPP21 R3HDM1

1.14e-044822IPR024771
DomainArgonaute_N

AGO1 AGO4

1.14e-044822IPR032474
DomainArgonaute_Mid_dom

AGO1 AGO4

1.14e-044822IPR032473
DomainArgoL2

AGO1 AGO4

1.14e-044822IPR032472
DomainSUZ

ARPP21 R3HDM1

1.14e-044822PS51673
DomainArgoN

AGO1 AGO4

1.14e-044822PF16486
DomainArgoMid

AGO1 AGO4

1.14e-044822PF16487
DomainArgoL2

AGO1 AGO4

1.14e-044822PF16488
DomainDUF1785

AGO1 AGO4

1.89e-045822SM01163
DomainArgoL1

AGO1 AGO4

2.82e-046822PF08699
DomainArgoL1

AGO1 AGO4

2.82e-046822IPR014811
DomainSpectrin/alpha-actinin

AKAP6 SPTBN5 DST

3.69e-0432823IPR018159
DomainSPEC

AKAP6 SPTBN5 DST

3.69e-0432823SM00150
DomainPIWI

AGO1 AGO4

5.24e-048822PS50822
DomainPiwi

AGO1 AGO4

5.24e-048822SM00950
DomainPiwi

AGO1 AGO4

5.24e-048822IPR003165
DomainPiwi

AGO1 AGO4

5.24e-048822PF02171
DomainPAZ

AGO1 AGO4

6.72e-049822PS50821
DomainPAZ

AGO1 AGO4

6.72e-049822SM00949
DomainPAZ_dom

AGO1 AGO4

6.72e-049822IPR003100
DomainPAZ

AGO1 AGO4

6.72e-049822PF02170
DomainR3H

ARPP21 R3HDM1

6.72e-049822SM00393
DomainR3H

ARPP21 R3HDM1

1.02e-0311822PS51061
DomainR3H

ARPP21 R3HDM1

1.02e-0311822PF01424
Domain-

ARPP21 R3HDM1

1.02e-03118223.30.1370.50
DomainR3H_dom

ARPP21 R3HDM1

1.02e-0311822IPR001374
DomainCadherin_CS

FAT4 PCDHGA4 PCDHB15 PCDH12

1.35e-03109824IPR020894
DomainCADHERIN_1

FAT4 PCDHGA4 PCDHB15 PCDH12

1.55e-03113824PS00232
DomainCadherin

FAT4 PCDHGA4 PCDHB15 PCDH12

1.55e-03113824PF00028
DomainCADHERIN_2

FAT4 PCDHGA4 PCDHB15 PCDH12

1.60e-03114824PS50268
Domain-

FAT4 PCDHGA4 PCDHB15 PCDH12

1.60e-031148242.60.40.60
DomainCA

FAT4 PCDHGA4 PCDHB15 PCDH12

1.65e-03115824SM00112
DomainGelsolin

SEC24B SCIN

1.67e-0314822PF00626
DomainGelsolin-like_dom

SEC24B SCIN

1.67e-0314822IPR007123
DomainCadherin-like

FAT4 PCDHGA4 PCDHB15 PCDH12

1.70e-03116824IPR015919
DomainCadherin

FAT4 PCDHGA4 PCDHB15 PCDH12

1.81e-03118824IPR002126
DomainCadherin_2

PCDHGA4 PCDHB15 PCDH12

2.93e-0365823PF08266
DomainCadherin_N

PCDHGA4 PCDHB15 PCDH12

2.93e-0365823IPR013164
DomainPWWP

ZMYND8 HDGFL3

3.44e-0320822SM00293
PathwayBIOCARTA_DICER_PATHWAY

AGO1 AGO4

1.43e-045542M22079
PathwayREACTOME_MICRORNA_MIRNA_BIOGENESIS

AGO1 AGO4

2.14e-046542MM14818
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO1 AGO4

2.14e-046542MM15083
PathwayREACTOME_REGULATION_OF_HOMOTYPIC_CELL_CELL_ADHESION

AGO1 AGO4 AMOT

2.44e-0432543M48012
PathwayREACTOME_POST_TRANSCRIPTIONAL_SILENCING_BY_SMALL_RNAS

AGO1 AGO4

2.99e-047542M46421
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO1 AGO4

3.97e-048542MM15082
PathwayREACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION

AGO1 AGO4 SS18L1 CEACAM1

4.73e-0495544M48268
PathwayREACTOME_SMALL_INTERFERING_RNA_SIRNA_BIOGENESIS

AGO1 AGO4

5.10e-049542M27340
PathwayREACTOME_REGULATION_OF_PTEN_MRNA_TRANSLATION

AGO1 AGO4

5.10e-049542M27810
PathwayREACTOME_REGULATION_OF_NPAS4_MRNA_TRANSLATION

AGO1 AGO4

5.10e-049542M46436
PathwayREACTOME_REGULATION_OF_CDH11_MRNA_TRANSLATION_BY_MICRORNAS

AGO1 AGO4

6.35e-0410542M48013
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CDK18 DST RESF1 ZFP36L1 ATXN1 AMOT PRRC2C SEC24B DYRK1A MAP3K9 TAB2 R3HDM1 E2F8 EXOC4

2.55e-08861861436931259
Pubmed

Human transcription factor protein interaction networks.

AGO1 DST RESF1 EP400 ATXN1 PRRC2C SS18L1 SEC24B ZMYND8 SIX4 R3HDM1 FLG2 TEX10 KDM6A EXOC4

2.09e-061429861535140242
Pubmed

Interaction network of human early embryonic transcription factors.

RESF1 EP400 ATXN1 BAZ1A SS18L1 SIX4 FLG2 KDM6A

2.66e-0635186838297188
Pubmed

The Importance of AGO 1 and 4 in Post-Transcriptional Gene Regulatory Function of tRF5-GluCTC, an Respiratory Syncytial Virus-Induced tRNA-Derived RNA Fragment.

AGO1 AGO4

6.04e-06286233233493
Pubmed

UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis.

SIX4 KDM6A

6.04e-06286220300060
Pubmed

Effects of Echinococcus multilocularis miR-71 mimics on murine macrophage RAW264.7 cells.

AGO1 AGO4

6.04e-06286226995025
Pubmed

Genome-wide association between Six4, MyoD, and the histone demethylase Utx during myogenesis.

SIX4 KDM6A

1.81e-05386226229056
Pubmed

Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins.

AGO1 AGO4

1.81e-05386219946268
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

AKAP6 ZBTB38 DST ATXN1 AMOT MED12L TAB2 PCDH12

3.29e-0549786823414517
Pubmed

Molecular dissection of human Argonaute proteins by DNA shuffling.

AGO1 AGO4

3.61e-05486223748378
Pubmed

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs.

AGO1 AGO4

3.61e-05486215260970
Pubmed

Slicing-independent RISC activation requires the argonaute PAZ domain.

AGO1 AGO4

3.61e-05486222795694
Pubmed

ATP-dependent human RISC assembly pathways.

AGO1 AGO4

3.61e-05486219966796
Pubmed

Importance of translation and nonnucleolytic ago proteins for on-target RNA interference.

AGO1 AGO4

3.61e-05486218771919
Pubmed

A Requirement for Argonaute 4 in Mammalian Antiviral Defense.

AGO1 AGO4

3.61e-05486232049003
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

AKAP6 DST RESF1 TAB2 EXOC4

3.79e-0515186517043677
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

AMOT SEC24B NUFIP2 TAB2 R3HDM1 EXOC4

5.01e-0526386634702444
Pubmed

Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors.

AGO1 AGO4

6.01e-05586212526743
Pubmed

Differential expression of Dicer and Argonaute genes during the differentiation of human neuroblastoma cells.

AGO1 AGO4

6.01e-05586219393748
Pubmed

Gene expression profiles in mouse urethral development.

FZD1 DPT

6.01e-05586216978288
Pubmed

Differential expression of components of the microRNA machinery during mouse organogenesis.

AGO1 AGO4

6.01e-05586216036130
Pubmed

The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis.

AGO1 AGO4

6.01e-05586212414724
Pubmed

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing.

AGO1 AGO4

6.01e-05586219324964
Pubmed

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program.

DNAJC14 LOXL1 DNAJC5G IGSF11 EXOC4

6.84e-0517186528700664
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

AKAP6 ZBTB38 DST DNAJC14 ZMYND8 DYRK1A R3HDM1 LRP1B KDM6A ECE2 CAP2 EXOC4

7.54e-051285861235914814
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

EP400 ATXN1 BAZ1A ZMYND8 DYRK1A SIX4 FLG2 NFAT5

1.00e-0458386829844126
Pubmed

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

AGO1 AGO4

1.26e-04786219470757
Pubmed

Genome-wide identification of microRNA targets reveals positive regulation of the Hippo pathway by miR-122 during liver development.

AGO1 AGO4

1.26e-04786234907157
Pubmed

Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps.

AGO1 AGO4

1.26e-04786219536157
Pubmed

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

AGO1 AGO4

1.26e-04786219383768
Pubmed

Mouse ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes.

PCDH12 CAP2

1.68e-04886218246200
Pubmed

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

AGO1 AGO4

1.68e-04886219345100
Pubmed

Suppression of microRNA Activity in Kidney Collecting Ducts Induces Partial Loss of Epithelial Phenotype and Renal Fibrosis.

AGO1 AGO4

1.68e-04886229021386
Pubmed

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

NFAT5 LRP1B ECE2

2.05e-044686321102462
Pubmed

A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

CDK18 NEU1 BAZ1A AMOT TAB2

2.13e-0421886519460752
Pubmed

Identification of eight members of the Argonaute family in the human genome.

AGO1 AGO4

2.15e-04986212906857
Pubmed

Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation.

COL8A1 FAT4

2.15e-04986231747096
Pubmed

PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.

AMOT PRRC2C TAB2

2.48e-044986331762063
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

DST RESF1 PRRC2C ZMYND8

2.53e-0412386426912792
Pubmed

Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.

PRRC2C NUFIP2 HNRNPAB

2.96e-045286326265008
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

DST RESF1 EP400 NFAT5

3.12e-0413086412421765
Pubmed

Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth.

FAT4 AMOT

3.28e-041186228239148
Pubmed

The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts.

ARPP21 R3HDM1

3.28e-041186229581509
Pubmed

Analysis of HIV-1 Gag protein interactions via biotin ligase tagging.

SEMG2 PRRC2C NUFIP2

3.31e-045486325631074
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

AKAP6 DST AGO4 EP400 AMOT MED12L CEP126

3.45e-0452986714621295
Pubmed

Regulation of neuronal migration by Dchs1-Fat4 planar cell polarity.

FAT4 EPHA4

3.93e-041286224998526
Pubmed

The LMO2 oncogene regulates DNA replication in hematopoietic cells.

BAZ1A TAB2 MCM6

4.08e-045886326764384
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

CDK18 AMOT SEC24B NUFIP2 DYRK1A UBAC2 MCM6 NCLN CWC25 TULP1 EXOC4

4.10e-041321861127173435
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

AGO1 DST AGO4 NUFIP2 DYRK1A MAP3K9 TEX10 RIOK2 EPHA4

4.20e-0491086936736316
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

EP400 AMOT PRRC2C SEC24B NUFIP2 KDM6A EXOC4

4.31e-0454986738280479
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

EP400 BAZ1A ZMYND8 MCM6 HNRNPAB EXOC4

4.46e-0439486627248496
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

DST PRRC2C NUFIP2 R3HDM1 HNRNPAB

4.61e-0425886537794589
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

COL8A1 FAT4 DST AMOT MAP3K9 SLFN5 CSMD2 CFAP44

4.81e-0473686829676528
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

DPT COL8A1 LOXL1 HDGFL3

4.85e-0414686427068509
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

DST EP400 BAZ1A PRRC2C SEC24B NUFIP2 ZMYND8 SCIN HNRNPAB

5.07e-0493486933916271
Pubmed

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

DST IGSF11 NFAT5 LRP1B

5.23e-0414986425231870
Pubmed

MicroRNA profile of the developing mouse retina.

ARPP21 R3HDM1

5.39e-041486219933188
Pubmed

A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.

HNRNPAB HDGFL3

5.39e-041486226912663
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

NEU1 EP400 BAZ1A PRRC2C NUFIP2 MPLKIP UMPS FLG2 TEX10 CWC25 RIOK2

5.59e-041371861136244648
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FAT4 EP400 SEC24B NUFIP2 DACT2 IL1RN HNRNPAB EXOC4

5.64e-0475486835906200
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

EP400 BAZ1A PRRC2C SS18L1 NUFIP2 ZMYND8 CWC25 HNRNPAB HDGFL3

5.90e-0495486936373674
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

AGO1 AMOT SEC24B R3HDM1 HNRNPAB

6.06e-0427486534244482
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RESF1 EP400 PRRC2C TAB2 CFAP44 SCIN EXOC4

6.46e-0458886738580884
Pubmed

Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs.

AGO1 AGO4

7.09e-041686220102707
Pubmed

Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.

CDK18 DST PRRC2C DYRK1A FLG2 RIOK2

7.22e-0443286623455922
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

BAZ1A PRRC2C NUFIP2 ZMYND8 MCM6 FLG2 HNRNPAB

7.64e-0460586728977666
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGA4 PCDHB15 PCDH12

7.70e-047286310380929
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

EP400 AMOT NUFIP2 DYRK1A MCM6 TEX10

7.94e-0444086634244565
Pubmed

LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.

PRRC2C NUFIP2

8.02e-041786237072811
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGA4 PCDHB15 PCDH12

8.34e-047486310817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHGA4 PCDHB15 PCDH12

9.36e-047786310835267
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DST EP400 BAZ1A AMOT MCM6 NCLN TEX10 SCIN HNRNPAB

9.72e-04102486924711643
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

AGO1 AGO4 PRRC2C NUFIP2 UBAC2 HNRNPAB

1.02e-0346286631138677
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGA4 PCDHB15 PCDH12

1.05e-038086310716726
Pubmed

Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.

NEU1 AGO4 SEC24B

1.05e-038086316094384
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

MCM6 NCLN FLG2 NFAT5 EXOC4

1.08e-0331286537120454
Pubmed

Regulation of epidermal differentiation through KDF1-mediated deubiquitination of IKKα.

AMOT SEC24B NUFIP2 MCM6

1.10e-0318286432239614
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

DST EP400 AMOT NUFIP2 DYRK1A CAP2 EXOC4

1.11e-0364586725281560
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

DST EP400 BAZ1A ZMYND8 SIX4 HNRNPAB

1.14e-0347286638943005
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

EP400 SIX4 KDM6A

1.16e-038386328794006
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

COL8A1 AGO1 DST SEC24B TAB2 MCM6 NCLN HNRNPAB

1.17e-0384486825963833
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

EP400 BAZ1A PRRC2C ZMYND8 DYRK1A MCM6 SIX4 TEX10

1.29e-0385786825609649
Pubmed

Lipid signatures reflect the function of the murine primary placentation†.

SLC16A4 PCDH12

1.35e-032286234850819
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ZBTB38 AGO1 DST EP400 SS18L1 ZMYND8 FLG2 TEX10 HNRNPAB

1.42e-03108286938697112
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AKAP6 RESF1 BAZ1A AMOT DYRK1A MAP3K9 TAB2 NFAT5 E2F8

1.44e-03108486911544199
Pubmed

Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis.

IL1RN EPHA4

1.48e-032386219571816
Pubmed

Tagging genes with cassette-exchange sites.

RESF1 PRRC2C ZMYND8 HNRNPAB EPHA4

1.48e-0333586515741177
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

EP400 PSMC3IP MCM6 TEX10 HNRNPAB

1.56e-0333986530415952
Pubmed

Gene network analysis in a pediatric cohort identifies novel lung function genes.

MED12L IGSF11

1.61e-032486224023788
Pubmed

The RNA-binding protein Snd1/Tudor-SN regulates hypoxia-responsive gene expression.

AMOT PRRC2C NUFIP2

1.82e-039786337151849
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

COL8A1 DST EP400 BAZ1A SEC24B MCM6 TEX10 RIOK2 HNRNPAB EXOC4

1.86e-031353861029467282
Pubmed

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2.

AGO1 AGO4

1.89e-032686219898466
Pubmed

Spatial centrosome proteome of human neural cells uncovers disease-relevant heterogeneity.

AGO1 NUFIP2

2.04e-032786235709258
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

AGO4 RESF1 MED12L

2.04e-0310186310997877
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

DPT COL8A1 LOXL1

2.04e-0310186320551380
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

AMOT PRRC2C UMPS UBAC2 MCM6 ALDH6A1

2.12e-0353486635032548
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

PRRC2C NUFIP2 UMPS UBAC2 MCM6 NCLN HNRNPAB

2.15e-0372586727025967
Pubmed

Maternal DNA Methylation Regulates Early Trophoblast Development.

DST PCDH12

2.19e-032886226812015
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

SEC24B NUFIP2 UMPS UBAC2 MCM6 NCLN TEX10 EXOC4

2.32e-0394286831073040
Pubmed

Identification of novel transcription-regulating genes expressed during murine molar development.

ZFP36L1 HNRNPAB

2.35e-032986222639370
InteractionEGR2 interactions

RESF1 EP400 ATXN1 SS18L1 SIX4 FLG2 KDM6A

6.23e-06171827int:EGR2
InteractionR3HDM2 interactions

ARPP21 AGO1 ATXN1 PRRC2C SEC24B R3HDM1

1.44e-05129826int:R3HDM2
GeneFamilyEF-hand domain containing|S100 fused type protein family

RPTN FLG2

1.75e-0475321350
GeneFamilyArgonaute/PIWI family

AGO1 AGO4

2.33e-048532408
GeneFamilyCD molecules|Membrane spanning 4-domains

MS4A18 MS4A12

1.25e-0318532958
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

DST BAZ1A PRRC2C SEC24B ZMYND8 DYRK1A TAB2 R3HDM1 CAP2 EPHA4

2.73e-064668510M13522
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

FZD1 COL8A1 DST ZFP36L1 ATXN1 CEP126 CFAP44 ALDH6A1 LRP1B GASK1B

1.68e-055748510M39056
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

COL8A1 DST ATXN1 BAZ1A PRRC2C SEC24B ZMYND8 DYRK1A TAB2 R3HDM1 CAP2 EPHA4

2.01e-058568512M4500
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL1

FZD1 ZFP36L1 ATXN1 MED12L CEP126 CFAP44 GASK1B CAP2

2.43e-05364858M39057
CoexpressionGSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN

ARPP21 NTAN1 NCLN KDM6A ENTPD4 E2F8

3.98e-05193856M6903
CoexpressionDURAND_STROMA_S_UP

AKAP6 FZD1 CDK18 FAT4 AGO4 LOXL1 PCDHB15

5.52e-05300857M2581
CoexpressionDURAND_STROMA_S_UP

AKAP6 FZD1 CDK18 FAT4 AGO4 LOXL1 PCDHB15

6.00e-05304857MM1083
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

AGO1 AGO4 BAZ1A AOC2 SIX4 CSMD2

4.51e-07149866768877bade04ca0321593b8470b5011ad8270431
ToppCellwk_15-18-Mesenchymal-Fibroblast-Mesenchymal_3|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AMOT PCDHB15 ZNF620 LRP1B GASK1B EPHA4

1.08e-06173866b43817a6b1ed8d6b5366702343be4311c0d52d83
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST RESF1 ZFP36L1 PRRC2C NUFIP2 MED12L

1.15e-061758661ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

DPT COL8A1 LOXL1 PCDHB15 CSMD2 CAP2

1.19e-06176866852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

DPT COL8A1 LOXL1 PCDHB15 CSMD2 CAP2

1.19e-06176866d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

FZD1 COL8A1 NTAN1 PRRC2C LOXL1 GASK1B

2.50e-06200866eabb7d4aa92ace7d970bcd3fae2c7cb5400a43b4
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ARPP21 R3HDM1 CFAP44 CAP2 EPHA4

8.56e-061438655fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

AKAP6 ARPP21 DST ALDH6A1 LRP1B

1.52e-05161865347edb0de10850b7d16c40945751033289289c9b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

AGO1 AGO4 AMOT MED12L TAB2

1.57e-05162865810881210e015c788814e4fe8d7a24c929cf2621
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL8A1 ARPP21 DACT2 R3HDM1 EPHA4

1.61e-051638651e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

COL8A1 ARPP21 DACT2 R3HDM1 EPHA4

1.61e-05163865431221a41d396b09170476179590eaf8a55266d8
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC24B SLFN5 SIX4 E2F8 ECE2

1.76e-05166865de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST RESF1 ZFP36L1 PRRC2C NUFIP2

2.15e-05173865869da6a65d1b9b7529c666ec44e3c8ddec2ea408
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST RESF1 ZFP36L1 PRRC2C NUFIP2

2.15e-051738650672bd8a4a9d18af343d01f09253fb3388896c10
ToppCellfacs-Brain_Myeloid-Cerebellum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST RESF1 ZFP36L1 PRRC2C NUFIP2

2.15e-05173865870e091ec30be01a900e1cb8b9ef1880e3b7b50d
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 SS18L1 AOC2 SCIN C16orf89

2.33e-051768657292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AKAP6 ZBTB38 PRRC2C NUFIP2 KDM6A

2.33e-05176865749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 SS18L1 AOC2 SCIN C16orf89

2.33e-0517686588ca2f83d8301633232735f39b0683efe49d0b86
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

AKAP6 ARPP21 DST ZNF37A LRP1B

2.40e-05177865e8ab340b20cd41554c3841fe980e078e878af35f
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRC2C LOXL1 PCDH12 EPHA4 C16orf89

2.60e-05180865dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRRC2C LOXL1 PCDH12 EPHA4 C16orf89

2.60e-05180865423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZFP36L1 PRRC2C NUFIP2 LRP1B GASK1B

3.04e-0518686523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 DPT LOXL1 GASK1B EPHA4

3.36e-051908658cb950effc449ae59a915132ecc079be54d1acfe
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 DPT LOXL1 GASK1B EPHA4

3.36e-051908655dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 DPT LOXL1 GASK1B EPHA4

3.36e-0519086517a73a658fb30a4322b31e38db7b240023738f29
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPT ZFP36L1 GASK1B CAP2 EPHA4

3.62e-051938657cd9671e0ac64f7f3607f564485c63abbb7e7a63
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ARPP21 FLG2 CSMD2 IL1RN LRP1B

3.81e-05195865d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell(3)_Chondrocytes-(30)_Chondro|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

FZD1 FAT4 ZFP36L1 LOXL1 EPHA4

3.81e-05195865f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ARPP21 FLG2 CSMD2 IL1RN LRP1B

3.81e-0519586519853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell343B-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

AKAP6 FZD1 ZFP36L1 PCDH12 GASK1B

3.81e-0519586567b05a0cd2ca9924eca81a92cc6330eecb9d963c
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARPP21 DNAJC5G R3HDM1 CSMD2 EPHA4

3.81e-05195865787e95fb59c40bba784544b662fac37606ae1427
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZBTB38 BAZ1A PRRC2C ZNF620 SIX4

3.90e-05196865ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FZD1 FAT4 DST ZFP36L1 LOXL1

4.00e-0519786573a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FZD1 DPT COL8A1 FAT4 LOXL1

4.09e-05198865300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

RESF1 BAZ1A PRRC2C SLFN5 CEP126

4.19e-0519986561b1ed2db71b96157b92b7535d1955a4033098da
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FAT4 DST AGO4 RESF1 PCDH12

4.29e-05200865dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC16A4 SLFN5 CEACAM1 C16orf89

1.21e-04131864308ddb7fe113eac5dbeb9cb0b688d9e09275ce5e
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_STALK-Flt1_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

SLC16A4 SLFN5 CEACAM1 C16orf89

1.25e-0413286406e7337de35bd7120655a22b6020604ad004c4e1
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND01-03-samps / Age Group, Lineage, Cell class and subclass

AKAP6 DPT LOXL1 FNDC4

1.44e-0413786425b5370b63644351efddb8749ef174beca0581cd
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC16A4 SLFN5 CEACAM1 C16orf89

1.52e-0413986434398a6f21a1e670497655a7bb7f3cde9e117560
ToppCellHippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC16A4 SLFN5 CEACAM1 C16orf89

1.52e-04139864450c4152c9fe4ec503271bb3cf93739918c59509
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARPP21 DACT2 R3HDM1 EPHA4

1.94e-04148864223d6a640f3c34e73646a615593b9c0b4a4cbd6f
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SLC16A4 SLFN5 CEACAM1 C16orf89

1.99e-04149864d9c47f523c75ddcd6131e45d2ffc24b970932cae
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_STALK|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC16A4 SLFN5 CEACAM1 C16orf89

2.25e-04154864b0735365de153d4586ca17896431d7bd9c7d8eac
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_macrophage-microglial_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FZD1 DST MED12L SCIN

2.43e-04157864d4908cafd8870c1c225817f589ea2bce116ac7ab
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC16A4 SLFN5 CEACAM1 C16orf89

2.86e-041648646a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC16A4 SLFN5 CEACAM1 C16orf89

2.86e-04164864ec68954fc09b6850273b5e59caa6b09d02151097
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK|Cerebellum / BrainAtlas - Mouse McCarroll V32

SLC16A4 SLFN5 CEACAM1 C16orf89

2.93e-041658647d319a112b9062efee428bef6f4534d2ce782e04
ToppCellBronchial_Brush-Epithelial-Goblet_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

SEMG2 FAT4 IL1RN CEACAM1

3.00e-041668648ac0a769be886d16642e7e6334471ebadd1a426b
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

RESF1 DNAJC14 ZNF37A CFAP44

3.00e-0416686432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SLC16A4 SLFN5 CEACAM1 C16orf89

3.00e-0416686427af6c906cff1d40d134f0386db7708869691121
ToppCelldroplet-Lung-LUNG-1m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSMC3IP FNDC4 MCM6 SCIN

3.07e-04167864e30e7ac8ea4399dc3c1d94fc6b857afc80a7a671
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDK18 SS18L1 SLFN5 NCLN

3.07e-04167864d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCellBronchial_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SEMG2 FAT4 IL1RN CEACAM1

3.07e-04167864806d1c00c137da0c5f042adf866873eb6dd4bb27
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CDK18 ARPP21 DACT2 EPHA4

3.07e-04167864f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCell343B-Lymphocytic-NK_cells-Proliferating_NK_cell|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF620 PSMC3IP TEX10 E2F8

3.21e-0416986402fa66a91b8bd2bf971aec4f5ec58318b5bfdf14
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL8A1 SLC16A4 USP29 SCIN

3.21e-0416986458e22f9119240664515fe91ca53812611a8f17d6
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 FAT4 GASK1B C16orf89

3.28e-0417086450c6c571591aa4b218caefe5778c570c809f567e
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHB15 ENTPD4 GASK1B C16orf89

3.28e-041708648e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 FAT4 GASK1B C16orf89

3.28e-041708648fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCDHB15 ENTPD4 GASK1B C16orf89

3.28e-0417086467d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPT LOXL1 PSMC3IP MCM6

3.28e-04170864e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL8A1 FAT4 GASK1B C16orf89

3.28e-041708643232db50b1a40f861e981a1b9c9073b81af9f832
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-like-AT2_Progenitor|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPT CEP126 CFAP44 LRP1B

3.36e-04171864ca2775a17b5c339c480a963953b6fa2b0731f24d
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPT CEP126 CFAP44 LRP1B

3.36e-041718643ad4f138d9570500cfb4423a2be16bb7d1cacbf8
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

MED12L PSMC3IP MCM6 E2F8

3.43e-041728648d20eda599abf1e9e3e3b90f314acddee6a465a4
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FZD1 COL8A1 FAT4 DST

3.66e-041758641799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

DST SLFN5 HDGFL3 EPHA4

3.66e-041758640ed053aa8353c72ff37fee830672704a3ddc7d85
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

DST SLFN5 HDGFL3 EPHA4

3.66e-041758640124a3c4696b39cee8b566e94603d1d3d128bfa5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FZD1 DNAJC5G ZNF620 IL1RN

3.66e-04175864f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARPP21 R3HDM1 CAP2 EPHA4

3.66e-04175864ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DST SLFN5 HDGFL3 EPHA4

3.66e-04175864e219b61d6bc078d44ea7d06191d3462654d857a1
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_CD56bright-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DST SLFN5 HDGFL3 EPHA4

3.66e-04175864bd16c80418bf71127e6f1e50edf83967c9218b42
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDK18 COL8A1 USP29 FNDC4

3.66e-04175864085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARPP21 R3HDM1 CAP2 EPHA4

3.66e-0417586421f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLFN5 PCDH12 GASK1B EPHA4

3.74e-04176864eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DPT LOXL1 PSMC3IP MCM6

3.74e-04176864cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AKAP6 CEP126 CFAP44 SCIN

3.74e-04176864dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEU1 BAZ1A MCM6 IL1RN

3.74e-04176864270d7908dbd84028958d257f94941dc685e20255
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)|343B / Donor, Lineage, Cell class and subclass (all cells)

DPT FAT4 PCDHB15 FNDC4

3.82e-04177864e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-|343B / Donor, Lineage, Cell class and subclass (all cells)

DPT FAT4 PCDHB15 FNDC4

3.82e-0417786443ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5|TCGA-Skin / Sample_Type by Project: Shred V9

FZD1 COL8A1 SPEGNB LRP1B

3.91e-04178864ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZBTB38 PRRC2C SLFN5 CEACAM1

3.91e-0417886401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 DYRK1A GASK1B HDGFL3

3.91e-0417886409d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 PSMC3IP CFAP44 MORN3

3.91e-041788646178706db4a855d72abc156537604d575624df56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 PSMC3IP CFAP44 MORN3

3.91e-04178864f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-VLMC-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

COL8A1 GASK1B CAP2 C16orf89

3.99e-04179864381ac15d59f31bc613828bdcfbc9192b106b4d18
ToppCellCiliated_cells-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

AMOT LOXL1 DACT2 CFAP44

3.99e-041798641c41314b6fcfcac8d62034e7037570120d58f20f
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 CDK18 COL8A1 CAP2

4.07e-04180864f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPT COL8A1 LOXL1 GASK1B

4.07e-0418086439ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 CDK18 COL8A1 CAP2

4.07e-04180864dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPT COL8A1 LOXL1 GASK1B

4.16e-04181864269b39ac65790061d54eab47a8eeb024403f0348
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPT COL8A1 LOXL1 GASK1B

4.16e-04181864cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCellfacs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPT COL8A1 LOXL1 GASK1B

4.16e-04181864c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPT FAT4 DST CAP2

4.16e-04181864b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLFN5 PCDH12 GASK1B C16orf89

4.16e-041818642e15c46e8260bb04d8264478c19a707221996026
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST PCDHGA4 EPHA4 C16orf89

4.16e-041818644ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FZD1 DPT COL8A1 LOXL1

4.25e-04182864f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ARPP21 DNAJC5G R3HDM1 EPHA4

4.25e-0418286414a117c5e50db31ee1b2cf4df4d133451fd6d55f
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Trm/em_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ZBTB38 RESF1 ATXN1 SLFN5

4.25e-04182864f857b32de19240a8aca1685f7a78b4e53b04875c
DrugSB 202190; Down 200; 1uM; PC3; HT_HG-U133A

ZBTB38 AGO4 ZFP36L1 SCIN NFAT5 ALDH6A1 HDGFL3 EPHA4

5.71e-071958387058_DN
DrugDiloxanide furoate [3736-81-0]; Up 200; 12.2uM; HL60; HT_HG-U133A

AKAP6 SPTBN5 SLC16A4 LOXL1 PCDH12 SCIN IL1RN ALDH6A1

6.17e-071978383062_UP
Drugalpha-estradiol; Down 200; 0.01uM; HL60; HT_HG-U133A

SLC16A4 ZMYND8 DYRK1A IL1RN NFAT5 ALDH6A1 ENTPD4 HDGFL3

6.92e-072008382670_DN
Drugtrifluoperazine dihydrochloride; Up 200; 10uM; HL60; HT_HG-U133A

FZD1 SEMG2 ZBTB38 ZFP36L1 IL1RN CAP2 EPHA4

5.33e-061868372684_UP
Diseaselactase-phlorizin hydrolase measurement

MCM6 R3HDM1

2.16e-048832EFO_0801753
Diseaseovary epithelial cancer (is_implicated_in)

AKAP6 TAB2

4.23e-0411832DOID:2152 (is_implicated_in)
Diseasesyndromic intellectual disability (implicated_via_orthology)

ZMYND8 DYRK1A

9.14e-0416832DOID:0050888 (implicated_via_orthology)
Diseasestomach cancer (is_implicated_in)

IL1RN LRP1B KDM6A

1.11e-0372833DOID:10534 (is_implicated_in)
DiseaseCarcinoma of bladder

KDM6A EPHA4

1.16e-0318832C0699885
Diseasemaximal midexpiratory flow rate

MED12L IGSF11

1.44e-0320832EFO_0004313
Diseaseblood aluminium measurement

ZBTB38 EPHA4

1.44e-0320832EFO_0007575
Diseaseresponse to selective serotonin reuptake inhibitor

CSMD2 CAP2 EXOC4

1.62e-0382833EFO_0005658
Diseaseneutrophil percentage of leukocytes

ZBTB38 NEU1 ATXN1 MCM6 NCLN IL1RN TULP1

1.67e-03610837EFO_0007990
DiseaseHepatitis

DPT FAT4

1.74e-0322832HP_0012115
Diseasecarpal tunnel syndrome

ZBTB38 LOXL1 UMPS

2.05e-0389833EFO_0004143
Diseasealcohol consumption measurement

AKAP6 SPTBN5 ZBTB38 ATXN1 NUFIP2 DNAJC5G IGSF11 NFAT5 ECE2 EPHA4

2.52e-0312428310EFO_0007878

Protein segments in the cluster

PeptideGeneStartEntry
QLAGQRQSQQQYDPS

EP400

561

Q96L91
QQRQGNCQPTNVSEY

AMOT

641

Q4VCS5
GCTQGPLQQSQDYIN

C16orf89

211

Q6UX73
GYGLQVRNSDRNQGL

CWC25

226

Q9NXE8
VPQFGIQNNSQGYQV

CSMD2

3136

Q7Z408
IQNNSQGYQVGSTVL

CSMD2

3141

Q7Z408
GQLSPGVQFQRRQNQ

CDK18

71

Q07002
NGQVRYGIVNGNTNQ

FAT4

2186

Q6V0I7
LQYGGRNRAIATPNQ

AGO1

416

Q9UL18
LNRQGFSYQCPQGQV

DPT

41

Q07507
STGNQGNQAYQNRPV

DYRK1A

671

Q13627
GNQAYQNRPVAANTL

DYRK1A

676

Q13627
QYGGRNKTVATPNQG

AGO4

411

Q9HCK5
SGQQQAITYAGSLPQ

ATXN1

466

P54253
TLQNQQGNAFQGPRE

CFAP44

1786

Q96MT7
QAGYQPVLSGQQGFQ

ARPP21

676

Q9UBL0
GQQQEPGRYPSRSQQ

BAZ1A

1286

Q9NRL2
VIPNQQQNYQGIVGV

R3HDM1

686

Q15032
QQNYQGIVGVQQPQS

R3HDM1

691

Q15032
LQGQPYGTRNAVLNT

NCLN

56

Q969V3
TLYRTLRNQGNQGAP

PCDH12

821

Q9NPG4
SPQGSQYSVQGNLVV

AOC2

311

O75106
PDVGVNSLQGYQLNS

PCDHGA4

191

Q9Y5G9
QIVNNNPYGNGTAIF

ALDH6A1

436

Q02252
SQRGYGARENGQPQN

FLG2

351

Q5D862
QNINRQGNAPVASGR

DNAJC14

406

Q6Y2X3
APVNGINGYNEDINQ

MCM6

691

Q14566
GSQQQFGYSPGQQQT

MPLKIP

96

Q8TAP9
YSINVGQLNGPNCTR

LRP1B

4006

Q9NZR2
RQIQQQPSGYVQQQA

MED12L

1986

Q86YW9
QEQNRPYSSQDVFGN

PSMC3IP

21

Q9P2W1
YQVQTGGIIQSNPAK

DST

1816

Q03001
SGSNGNVPYLQRNAL

KDM6A

601

O15550
QGRLSVGSVYRPNQN

LOXL1

351

Q08397
PQNTGGRQDISYNVV

EPHA4

351

P54764
TYKNPSLRAQGGQTQ

CAP2

286

P40123
NQYQVNGERLNGRQT

ECE2

691

P0DPD6
DVGSNNVQNYNISPN

PCDHB15

161

Q9Y5E8
NPGVKFTGYQAIQQQ

HDGFL3

91

Q9Y3E1
SANGNLQQSPVYQQT

NFAT5

921

O94916
QDSGRKYQQNVQSQP

DNAJC5G

156

Q8N7S2
QQSGQQYNGERGISV

FZD1

96

Q9UP38
QGNGSTLQPNVVYIT

GASK1B

96

Q6UWH4
SGYQRGENVTVENQP

EXOC4

321

Q96A65
NANQPEQVILYQGGQ

IGSF11

66

Q5DX21
AQQTPSAQDYGRGNI

DACT2

446

Q5SW24
APENAGTQQGRATNY

E2F8

771

A0AVK6
NRQIVGYAIGTQQAT

CEACAM1

76

P13688
RQNPGSVGQKYSEQI

CEP126

971

Q9P2H0
IGYSISQQRQNGPGQ

FNDC4

76

Q9H6D8
NGRQNYNPQTGIFTC

COL8A1

641

P27658
NQNSAAGVQSQPIGY

MS4A18

66

Q3C1V0
RNNQLVAGYLQGPNV

IL1RN

51

P18510
QQPQSSQGTRYQTRQ

ZMYND8

851

Q9ULU4
TVNQQPGAQQLYSRG

SEC24B

106

O95487
TGQLNQRVGIFPSNY

MAP3K9

96

P80192
AQRNGLRSQVYAVNG

MORN3

21

Q6PF18
NQAQGAQRAQPYGIT

MS4A12

41

Q9NXJ0
QQQQYGSGGRGNRNR

HNRNPAB

236

Q99729
QYNIQNISTGPRKNQ

TAB2

311

Q9NYJ8
NYSKNTQIQVLPEGG

SCIN

321

Q9Y6U3
SNSTRLPVAYQGNQG

RESF1

171

Q9HCM1
LPVAYQGNQGLNQSF

RESF1

176

Q9HCM1
EIQQNGQTIYLRGTG

ENTPD4

376

Q9Y227
PDGSVVINARNQNNY

NEU1

271

Q99519
TQASNLYSGQVQQPG

PRRC2C

2551

Q9Y520
VQINQYGIVQIPNSG

SIX4

476

Q9UIU6
YGIVQIPNSGANSQF

SIX4

481

Q9UIU6
SQNQVRIPSQAQEYG

SEMG2

386

Q02383
DLGQYSINVTNPFGQ

SPEGNB

121

A0A087WV53
QSVQQVGPQGLLYVQ

NTAN1

36

Q96AB6
RQRYPGNSTQIQRQQ

SPTBN5

961

Q9NRC6
LQGLQDANGNYTRQT

AKAP6

166

Q13023
GQGTIGNYVSRTNIN

SS18L1

166

O75177
RPSQQGSSQQYLGQE

SS18L1

236

O75177
LGRNPINVVNEGNYS

ZNF37A

546

P17032
VFDNGQNPQRGYSTN

TULP1

381

O00294
TQKQPGGGQVNSSRY

ZFP36L1

101

Q07352
QNQSEEFYNGPNRNR

SLC16A4

256

O15374
IPNGVVTNNSGYITN

NUFIP2

186

Q7Z417
VPLSRNPGGNANYQV

SPEM2

446

Q0P670
NQTNPSGQISYECGQ

ZNF620

186

Q6ZNG0
QQLQQGFPNLGNTCY

USP29

281

Q9HBJ7
DNLGQQYNSPQEVIG

UMPS

426

P11172
QQHIQVYENGGSQPN

TEX10

276

Q9NXF1
VSSYQQALGQGPQFI

TRBV5-7

51

A0A0A0MS05
NPAIIRQAAGNYIGS

RRN3P2

281

A6NIE6
YNRQDGQRVQGGVPA

RIOK2

426

Q9BVS4
QNVNYQGGRQSEPAA

UBAC2

286

Q8NBM4
QRFLENYPTIGQNGG

ZBTB38

406

Q8NAP3
QGQGSHYSQPNRQGQ

RPTN

361

Q6XPR3
SGRLSQQTPGQEGYQ

RPTN

616

Q6XPR3
NSLGPQAAQGSVQYE

SLFN5

151

Q08AF3