Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentintegrin alpha2-beta1 complex

ITGB1 LYN

6.64e-053992GO:0034666
DomainDUF3398

DOCK9 DOCK10

4.03e-046982PF11878
DomainDOCK_C/D_N

DOCK9 DOCK10

4.03e-046982IPR021816
DomainDOCK_C

DOCK9 DOCK10

1.45e-0311982IPR010703
DomainDHR-1_domain

DOCK9 DOCK10

1.45e-0311982IPR027007
DomainDHR_2

DOCK9 DOCK10

1.45e-0311982PS51651
DomainDHR_1

DOCK9 DOCK10

1.45e-0311982PS51650
DomainDOCK-C2

DOCK9 DOCK10

1.45e-0311982PF14429
DomainDHR-2

DOCK9 DOCK10

1.45e-0311982IPR027357
DomainDHR-2

DOCK9 DOCK10

1.45e-0311982PF06920
DomainDOCK

DOCK9 DOCK10

1.45e-0311982IPR026791
DomainSH3_1

NEB SH3GLB1 SRGAP1 MAP3K21 LYN

1.73e-03164985PF00018
DomainSynaptotagmin

PCLO SYT11

4.87e-0320982IPR001565
DomainSH3

NEB SH3GLB1 SRGAP1 MAP3K21 LYN

5.62e-03216985SM00326
DomainSH3

NEB SH3GLB1 SRGAP1 MAP3K21 LYN

5.62e-03216985PS50002
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SART3 SAMD9 ERCC6 SYNM RBBP6 TM9SF3 MCM5 TUBGCP2 SRBD1 LGALS8 SRGAP1 SVIL MPHOSPH10 LYN IMMT SF3A2 RPL8

9.27e-081257991736526897
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

HSPG2 CCPG1 DOCK9 PRAMEF20 IREB2 DUSP16 PWWP3B TAF4B STAG2

1.01e-0636399914691545
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

HSPG2 MBTPS1 CCPG1 ENPP1 TM9SF3 ST6GAL1 SELENON ITGB1 LRRC8D NXPE3 SNX14 IGF1R SVIL CLPTM1 ATP6V0A2

1.55e-061201991535696571
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

CCPG1 PCLO TM9SF3 SELENON ITGB1 QSOX1 SNX14 CLPTM1 IMMT TMEM181

1.68e-06499991022810586
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

SART3 RBBP6 GPATCH1 MCM5 TUBGCP2 KIDINS220 SVIL ATP6V0A2

3.31e-0631399838270169
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

PMS1 SART3 UNC119B CCPG1 SYNM POLE2 ZDHHC5 TRAPPC8 ITGB1 KIDINS220 CLPTM1 VPS13A IFT80 IMMT RPL8 ATP6V0A2

4.56e-061487991633957083
Pubmed

Defining the membrane proteome of NK cells.

DOCK9 ZDHHC5 DOCK10 MCM5 TUBGCP2 ITGB1 LRRC8D OPA1 LGALS8 KIDINS220 CLPTM1 IMMT STAG2 RPL8

5.72e-061168991419946888
Pubmed

Selective modulation of type 1 insulin-like growth factor receptor signaling and functions by beta1 integrins.

ITGB1 IGF1R

8.02e-06299215289498
Pubmed

Protective effect of hyaluronic acid on interleukin-1-induced deregulation of beta1-integrin and insulin-like growth factor-I receptor signaling and collagen biosynthesis in cultured human chondrocytes.

ITGB1 IGF1R

8.02e-06299217899316
Pubmed

Gefitinib resistance in HCC mahlavu cells: upregulation of CD133 expression, activation of IGF-1R signaling pathway, and enhancement of IGF-1R nuclear translocation.

PROM1 IGF1R

8.02e-06299221959795
Pubmed

Cleavage of ST6Gal I by radiation-induced BACE1 inhibits golgi-anchored ST6Gal I-mediated sialylation of integrin β1 and migration in colon cancer cells.

ST6GAL1 ITGB1

8.02e-06299222449099
Pubmed

N-linked α2,6-sialylation of integrin β1 by the sialyltransferase ST6Gal1 promotes cell proliferation and stemness in gestational trophoblastic disease.

ST6GAL1 ITGB1

8.02e-06299238490094
Pubmed

Integrin expression regulates neuroblastoma attachment and migration.

ITGB1 IGF1R

8.02e-06299215256055
Pubmed

Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation.

HSPG2 HPSE

8.02e-06299218589009
Pubmed

Sialylation by β-galactoside α-2,6-sialyltransferase and N-glycans regulate cell adhesion and invasion in human anaplastic large cell lymphoma.

ST6GAL1 LGALS8

8.02e-06299225573487
Pubmed

Archvillin anchors in the Z-line of skeletal muscle via the nebulin C-terminus.

NEB SVIL

8.02e-06299218639526
Pubmed

Therapeutic targeting of Lyn kinase to treat chorea-acanthocytosis.

VPS13A LYN

8.02e-06299233941276
Pubmed

Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin β1.

ITGB1 CUL5

8.02e-06299230688657
Pubmed

Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.

HSPG2 ITGB1 PROM1

1.22e-051699321067603
Pubmed

The C-terminal domain V of perlecan promotes beta1 integrin-mediated cell adhesion, binds heparin, nidogen and fibulin-2 and can be modified by glycosaminoglycans.

HSPG2 ITGB1

2.40e-0539929431988
Pubmed

Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.

HSPG2 ITGB1

2.40e-05399215240572
Pubmed

Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, β1-integrin, and IGF-1R Signaling Pathways in an Experimental Model of Wounded Fibroblasts.

ITGB1 IGF1R

2.40e-05399233477899
Pubmed

The perlecan fragment LG3 regulates homing of mesenchymal stem cells and neointima formation during vascular rejection.

HSPG2 ITGB1

2.40e-05399225808553
Pubmed

Phosphoenolpyruvate-dependent inhibition of collagen biosynthesis, alpha2beta1 integrin and IGF-I receptor signaling in cultured fibroblasts.

ITGB1 IGF1R

2.40e-05399218491034
Pubmed

Reciprocal expressions between α-dystroglycan and integrin β1, perlecan receptors, in the murine enamel organ development.

HSPG2 ITGB1

2.40e-05399223722005
Pubmed

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

DOCK9 DOCK10

2.40e-05399232241915
Pubmed

Activation of β1 integrins and caveolin-1 by TF/FVIIa promotes IGF-1R signaling and cell survival.

ITGB1 IGF1R

2.40e-05399232458278
Pubmed

Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.

ITGB1 LGALS8

2.40e-05399219268462
Pubmed

Differential expression profiles between α-dystroglycan and integrin β1 in ameloblastoma: two possible perlecan signalling pathways for cellular growth and differentiation.

HSPG2 ITGB1

2.40e-05399221255062
Pubmed

Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.

HSPG2 ITGB1

4.79e-05499219789387
Pubmed

CHCHD10-regulated OPA1-mitofilin complex mediates TDP-43-induced mitochondrial phenotypes associated with frontotemporal dementia.

OPA1 IMMT

4.79e-05499232369233
Pubmed

Galectin-8 binding to integrins inhibits cell adhesion and induces apoptosis.

ITGB1 LGALS8

4.79e-05499210852818
Pubmed

Adhesion of ST6Gal I-mediated human colon cancer cells to fibronectin contributes to cell survival by integrin beta1-mediated paxillin and AKT activation.

ST6GAL1 ITGB1

4.79e-05499220127017
Pubmed

Platelet-Rich Plasma Promotes the Proliferation of Human Keratinocytes via a Progression of the Cell Cycle. A Role of Prolidase.

ITGB1 IGF1R

4.79e-05499233477820
Pubmed

ST6Gal-I restrains CD22-dependent antigen receptor endocytosis and Shp-1 recruitment in normal and pathogenic immune signaling.

ST6GAL1 LYN

4.79e-05499216782884
Pubmed

OPA1 and MICOS Regulate mitochondrial crista dynamics and formation.

OPA1 IMMT

4.79e-05499233130824
Pubmed

Abnormal expression of genes associated with development and inflammation in the heart of mouse maternal phenylketonuria offspring.

RYR2 PAH

4.79e-05499216164837
Pubmed

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.

ERCC6 CUL5

4.79e-05499228292928
Pubmed

Matrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domain.

ITGB1 LYN

4.79e-05499220159608
Pubmed

Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents.

HSPG2 ITGB1

4.79e-05499221747167
Pubmed

The L-isoaspartyl/D-aspartyl protein methyltransferase gene (PCMT1) maps to human chromosome 6q22.3-6q24 and the syntenic region of mouse chromosome 10.

RRM2 PAH

4.79e-0549921478665
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

SART3 RBBP6 GPATCH1 TUBGCP2 SRBD1 CUL5 SF3A2

5.63e-0534199732971831
Pubmed

Integrating genetic and network analysis to characterize genes related to mouse weight.

NEB RRM2 KIDINS220

7.75e-052999316934000
Pubmed

Heparanase localization during palatogenesis in mice.

HSPG2 HPSE

7.98e-05599223509775
Pubmed

Heparanase, heparan sulfate and perlecan distribution along with the vascular penetration during stellate reticulum retraction in the mouse enamel organ.

HSPG2 HPSE

7.98e-05599220684947
Pubmed

Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis.

HSPG2 HPSE

7.98e-05599217959718
Pubmed

The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan.

HSPG2 ITGB1

7.98e-0559929688542
Pubmed

Insulin and Insulin-Like Growth Factor 1 Signaling Preserves Sarcomere Integrity in the Adult Heart.

ITGB1 IGF1R

7.98e-05599236125265
Pubmed

Decorin regulates endothelial cell motility on collagen I through activation of insulin-like growth factor I receptor and modulation of alpha2beta1 integrin activity.

ITGB1 IGF1R

7.98e-05599218413316
Pubmed

Cloning, expression, and chromosomal localization of a mouse gene homologous to the germ cell migration regulator wunen and to type 2 phosphatidic acid phosphatases.

SYT11 PAH

7.98e-05599210662554
Pubmed

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

DOCK9 DOCK10

7.98e-05599215710388
Pubmed

MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation.

OPA1 IMMT

7.98e-05599232567732
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

SART3 HSPG2 MPHOSPH10 RIOK2 SF3A2 RPL8

8.51e-0525199628077445
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SART3 STRN3 ERCC6 RBBP6 TM9SF3 MCM5 SRBD1 LGALS8 KIDINS220 MPHOSPH10 IMMT SF3A2 STAG2 ATP6V0A2

8.73e-051497991431527615
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PMS1 SART3 SAMD9 ENPP1 DOCK10 COLGALT2 CUL5 TIMM29 RIOK2

1.02e-0465099938777146
Pubmed

Human colostrum: identification of minor proteins in the aqueous phase by proteomics.

HSPG2 CFB QSOX1 PROM1 SERPINC1

1.04e-0416299516502470
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

DOCK9 ZDHHC5 DOCK10 ITGB1 KIDINS220 SYT11 LYN

1.05e-0437799738117590
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

TM9SF3 TUBGCP2 ITGB1 OPA1 CLPTM1 VPS13A IMMT RPL8 ATP6V0A2

1.11e-0465799936180527
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

ERCC6 HAT1 MCM5 NEB QSOX1 IMMT SF3A2 RPL8

1.12e-0451399825798074
Pubmed

Binding of laminin-1 to monosialoganglioside GM1 in lipid rafts is crucial for neurite outgrowth.

ITGB1 LYN

1.19e-04699219118221
Pubmed

Expression and Roles of the Immunoglobulin Superfamily Recognition Molecule Sidekick1 in Mouse Retina.

SDK2 SLC6A3

1.19e-04699230687002
Pubmed

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.

DOCK9 DOCK10

1.19e-04699225851601
Pubmed

ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function.

OPA1 IMMT

1.19e-04699221081504
Pubmed

Functional genomics of the cilium, a sensory organelle.

IFT57 IFT80

1.19e-04699215916950
Pubmed

Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis.

HSPG2 ITGB1 PROM1

1.37e-043599318676816
Pubmed

Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.

SART3 POLE2 ITGB1 OPA1 SKA1

1.49e-0417599537866880
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

STRN3 CCPG1 TUBGCP2 CUL5 QSOX1 IGF1R SVIL TAF4B DNAH11

1.58e-0468999936543142
Pubmed

[Population study of the Udmurt population: analysis of ten polymorphic DNA loci of the nuclear genome].

SLC6A3 PAH

1.67e-04799217633563
Pubmed

RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix.

ITGB1 IGF1R

1.67e-04799211884618
Pubmed

Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.

RYR2 SLC6A3

1.67e-04799220962236
Pubmed

The application of the polymerase chain reaction to cloning members of the protein tyrosine kinase family.

IGF1R LYN

1.67e-0479922482828
Pubmed

Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.

MCM5 LYN

1.67e-04799223764002
Pubmed

A new molecular link between defective autophagy and erythroid abnormalities in chorea-acanthocytosis.

VPS13A LYN

1.67e-04799227742708
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MBTPS1 DOCK9 DOCK10 OPA1 KIDINS220 SYT11 TMEM181

1.69e-0440799712693553
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

TUBGCP2 ITGB1 OPA1 CLPTM1 VPS13A IMMT RPL8

1.71e-0440899733766124
Pubmed

Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.

HPSE CLPTM1 SERPINC1

1.76e-043899316263699
Pubmed

Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection.

IREB2 RRM2 CFB IGF1R

2.04e-0410199420587610
Pubmed

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis.

TM9SF3 ZDHHC5 ITGB1 VPS13A RIOK2 IMMT

2.20e-0429999637931956
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

RBBP6 MCM5 ITGB1 OPA1 IGF1R SVIL MLLT3 MPHOSPH10 LYN IMMT SF3A2 RPL8

2.24e-041247991227684187
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

SART3 STRN3 PCLO TM9SF3 MCM5 SRBD1 NEB RYR2 VPS13A MPHOSPH10 IMMT SF3A2 STAG2

2.28e-041442991335575683
Pubmed

Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.

HSPG2 CFB SERPINC1

2.72e-044499331273033
Pubmed

Examination of association to autism of common genetic variationin genes related to dopamine.

SLC6A3 PAH

2.85e-04999219360691
Pubmed

Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches.

NDNF SLC6A3

2.85e-04999230104732
Pubmed

Functional proteomics mapping of a human signaling pathway.

HSPG2 ERCC6 RBBP6 RYR2 CUL5 PAPPA MPHOSPH10 SF3A2

2.93e-0459199815231748
Pubmed

Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.

IFT57 TM9SF3 RRM2 VPS13A IFT80

3.38e-0420999526389662
Pubmed

The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas.

NDNF SDK2 SLC6A3

3.53e-044899332386544
Pubmed

Interaction of mouse TTC30/DYF-1 with multiple intraflagellar transport complex B proteins and KIF17.

IFT57 IFT80

3.56e-041099223810713
Pubmed

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.

HSPG2 ITGB1

3.56e-041099216554364
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

SYNM GPATCH1 ZDHHC5 ITGB1 RYR2 KIDINS220 VPS13A RPL8 ATP6V0A2

3.83e-0477799935844135
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

MBTPS1 TM9SF3 ZDHHC5 MCM5 TRAPPC8 ITGB1 KIDINS220 CLPTM1 LYN RPL8

3.90e-04952991038569033
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

STRN3 SAMD9 SRBD1 RRM2 ITGB1 CUL5 MPHOSPH10

4.13e-0447299738943005
Pubmed

Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.

HSPG2 ITGB1

4.34e-041199217023412
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

SART3 HAT1 MCM5 TUBGCP2 RRM2 IMMT STAG2 RPL8

4.86e-0463899833239621
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TM9SF3 COLGALT2 NEB RYR2 VPS13A MPHOSPH10 STAG2 DNAH11

4.86e-0463899831182584
Pubmed

Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors.

SLC6A3 PROM1

5.20e-041299227246266
Pubmed

Kindlin-2 Is Essential for Preserving Integrity of the Developing Heart and Preventing Ventricular Rupture.

HSPG2 ITGB1

5.20e-041299230883226
Pubmed

Synergistic activities of alpha3 and alpha6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse.

HSPG2 ITGB1

5.20e-041299210433923
Pubmed

Accelerated failure time models provide a useful statistical framework for aging research.

IGF1R PAPPA

5.20e-041299219007875
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

ERCC6 DOCK9 NEB OPA1 SNX14 IGF1R TRANK1

5.60e-0449799736774506
Pubmed

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.

TM9SF3 ZDHHC5 CLPTM1 IMMT ATP6V0A2

5.76e-0423599532614325
Cytoband10p11.2

ITGB1 SVIL

1.28e-04899210p11.2
Cytoband7q21.2

SAMD9 RBM48

4.75e-04159927q21.2
CytobandEnsembl 112 genes in cytogenetic band chr7q21

SAMD9 PCLO RBM48 ZNF804B

6.17e-04178994chr7q21
CoexpressionGSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_DN

ERCC6 IFT57 SRBD1 NXPE3 GBA3 CLPTM1 DENND6B SKA1

9.09e-07199998M4984
CoexpressionGSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN

POLE2 RRM2 HPSE NXPE3 SYT11 SVIL IMMT

4.66e-06175997M6694
CoexpressionGSE17721_0.5H_VS_8H_POLYIC_BMDC_DN

IFT57 TM9SF3 ZDHHC5 HAT1 IREB2 ITGB1 ATP6V0A2

1.08e-05199997M4094
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

SART3 RBBP6 PCLO MYT1 HAT1 LRRC8D PROM1 SYT11 SRGAP1 VPS13A MLLT3 PAPPA MPHOSPH10 IFT80 SKA1 TMEM181

1.13e-059899816Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

RBBP6 PCLO LRRC8D OPA1 PROM1 DUSP16 VPS13A PAPPA MPHOSPH10

2.11e-05328989Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_top-relative-expression-ranked_100

NDNF SYNM MCM5 SRGAP1 ZCRB1

4.37e-0584985gudmap_developingKidney_e15.5_stage III -IV renal corpusc_100
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5

NDNF PCLO PROM1 MLLT3 PAPPA MPHOSPH10 SKA1

4.50e-05204987Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

IFT57 RBBP6 PCLO NEB LRRC8D OPA1 PROM1 DUSP16 VPS13A MLLT3 PAPPA MPHOSPH10

4.77e-056549812Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

SART3 UNC119B RBBP6 PCLO LRRC8D PROM1 SRGAP1 VPS13A MLLT3 PAPPA MPHOSPH10 IFT80 SKA1

1.14e-048319813Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NDNF COLGALT2 NEB SLC6A3 TMEM232 PAPPA GSG1L

9.18e-081669976a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

ENPP1 PCLO ZNF804B PAH SLC28A1 PWWP3B WDR72

1.65e-071819976980ea624151da32b7f537f263e40fcb87a02e81
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO ZNF804B PAH SLC28A1 PAPPA WDR72

2.91e-0617899623a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO ZNF804B PAH SLC28A1 PAPPA WDR72

3.42e-0618399684b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO ZNF804B PAH SLC28A1 PAPPA WDR72

3.64e-061859961bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

ENPP1 ZNF804B PAH SLC28A1 PWWP3B WDR72

3.87e-06187996acd305475f3609800af0d7bc68d83ef41228080b
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

NEB RYR2 IGF1R CPLX3 SVIL GSG1L

3.99e-061889966d249fe92d51a19da19ec14bb2262d394255d577
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer|World / Primary Cells by Cluster

DOCK9 PCLO RYR2 LGALS8 KIDINS220 SRGAP1

5.69e-06200996db10f76938af553d1a2275bb02ef75dff3c3135b
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Upper_Layer-21|World / Primary Cells by Cluster

DOCK9 PCLO RYR2 LGALS8 KIDINS220 SRGAP1

5.69e-0620099630a3e4aee12ec1b5acdce90f86c9733c27a7f6fc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDNF DOCK10 COLGALT2 CPLX3 ZNF804B

8.52e-06124995690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 QSOX1 SRGAP1 SLC28A1 MLLT3

2.01e-05148995f58804d24fe524b42b5090c8658050ea4b14793e
ToppCell368C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 RRM2 TRANK1 TMEM232 SKA1

2.14e-05150995c3ad5fa41eb636a5d691c0268c0f1c32cd0de658
ToppCell368C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ERCC6 RRM2 TRANK1 TMEM232 SKA1

2.14e-0515099578b8029e71d26f336a46274c8afef3435bf536b9
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

UNC119B PROM1 TMEM232 DENND6B IFT80

3.28e-051649959e16e52f5a634585f26021bcce9b5d5992ff6db0
ToppCell3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3|GI_small-bowel / Manually curated celltypes from each tissue

SDK2 ENPP1 ITGB1 IGF1R SVIL

3.48e-05166995773673a5d0430640439845b264740bfbbdad0cb2
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAT1 MCM5 NEB RRM2 TAF4B

3.58e-05167995859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DOCK10 ITGB1 SYT11 SLC28A1 TMEM181

4.24e-0517399536a471576a9d2325066bb14c2f2cd89c67b92915
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_TBCC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SDK2 SAMD9 ENPP1 CPLX3 GSG1L

4.35e-05174995912a9e892b29d945666fc37c986009c97c668ac8
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NDNF NEB NXPE3 SYT11 MLLT3

4.47e-051759953bdccb4037053795d62ab5b6fcc09cdd406f9b50
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NDNF NEB NXPE3 SYT11 MLLT3

4.47e-05175995770546ddaa49ee482c4c7577ab76efbc6c304a29
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMS1 MCM5 RRM2 NXPE3 IFT80

4.72e-05177995f10f77130dbb2c0ad1b436ceb4fb1deac2b0267c
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYNM ENPP1 RYR2 SVIL ZNF804B

4.85e-051789958ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCellcellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SYNM ENPP1 RYR2 SVIL ZNF804B

4.85e-051789956c91331196696e0cf239d105f458e3230659fa38
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO ZNF804B PAH SLC28A1 WDR72

5.12e-05180995f8bdfd7bf7b3d52c659a29d8f5f80858e79da83e
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO PAH SLC28A1 PAPPA WDR72

5.12e-05180995358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

ENPP1 PAH SLC28A1 PAPPA WDR72

5.12e-05180995864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDNF SDK2 DOCK10 IL1F10 CPLX3

5.25e-0518199503a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NDNF SDK2 PANX3 PAPPA WDR72

5.39e-05182995193cb2df3d7ea4cb9a11390b92955e7d9b0a053a
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO PROM1 ZNF804B SLC28A1 WDR72

5.39e-051829959d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO ZNF804B PAH SLC28A1 WDR72

5.53e-05183995facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NEB RYR2 TRANK1 DNAH11

5.68e-051849952cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NEB RYR2 TRANK1 DNAH11

5.68e-05184995ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCLO NEB RYR2 TRANK1 DNAH11

5.68e-051849952b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SDK2 PANX3 DUSP16 PAPPA PWWP3B

5.82e-051859950094f9baddb20214d2a2c166f1637d1a9cf1169a
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

ENPP1 VPS13A SLC28A1 PAPPA WDR72

6.13e-05187995d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellCOVID-19-kidney|COVID-19 / Disease (COVID-19 only), tissue and cell type

PCLO PROM1 SLC28A1 PAPPA WDR72

6.13e-05187995d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDNF SDK2 DOCK10 CPLX3 ZNF804B

6.29e-05188995ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804B PAH SLC28A1 PAPPA WDR72

6.44e-05189995204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804B PAH SLC28A1 PAPPA WDR72

6.44e-0518999513fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804B PAH SLC28A1 PAPPA WDR72

6.77e-051919953c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF804B PAH SLC28A1 PAPPA WDR72

6.77e-051919951c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM9SF3 ITGB1 CUL5 PROM1 STAG2

6.77e-0519199509db184cb90fe282a14474d7217068c58092c6f8
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 RYR2 SRGAP1 PAPPA GSG1L

6.94e-05192995162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SDK2 RYR2 SRGAP1 PAPPA GSG1L

6.94e-05192995ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

ST6GAL1 PROM1 MLLT3 PAPPA MAP3K21

7.11e-05193995738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO PROM1 TMEM232 MAP3K21 WDR72

7.29e-0519499593c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCPG1 TM9SF3 ST6GAL1 CFB QSOX1

7.47e-051959952a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCPG1 TM9SF3 ST6GAL1 CFB QSOX1

7.47e-05195995576142b4e75457c0973051bccc4163bd624496af
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCPG1 TM9SF3 ST6GAL1 CFB QSOX1

7.47e-051959958f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCellmild-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

POLE2 HAT1 MCM5 RRM2 SKA1

7.65e-05196995b1d9866d5dfaefdb8bedaf01a750d97987acb3d1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PMS1 CFAP47 RBBP6 CCDC38 DNAH11

7.65e-051969957e98380d815fbf6254289ace2af37aac6fef51e8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCLO PROM1 TMEM232 MAP3K21 WDR72

7.65e-051969956ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellfacs-Trachea-3m|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STRN3 MBTPS1 CCPG1 TM9SF3 ITGB1

7.84e-05197995e77016d64b1cac9825fec7cfe5071f1567401187
ToppCellfacs-Trachea-nan-3m|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STRN3 MBTPS1 CCPG1 TM9SF3 ITGB1

7.84e-051979950353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCellsevere-Lymphocytic-Prol._cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

POLE2 HAT1 MCM5 RRM2 SKA1

8.03e-051989954d8591eabb543ed789f963b507a07c560c76a7c9
ToppCellmoderate-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CCPG1 TM9SF3 ST6GAL1 ITGB1 CFB

8.03e-051989957ecce5e266bb08797088cc8f8309e0c7b48df5c9
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

SAMD9 POLE2 DOCK9 TRANK1 DUSP16

8.03e-05198995ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell10x5'-GI_large-bowel-Lymphocytic_B|GI_large-bowel / Manually curated celltypes from each tissue

MCM5 ST6GAL1 RRM2 LYN RPL8

8.03e-051989954fac7cdc93dc2037bae41f350b332c30b79c13fb
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SAMD9 RBBP6 ITGB1 ZCRB1 STAG2

8.22e-0519999561b1ed2db71b96157b92b7535d1955a4033098da
ToppCellNeuron|World / Primary Cells by Cluster

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.22e-051999951f8104fd92f04690b41d9d07ac08dc59d76bb97d
ToppCellNeuron-Postmitotic|World / Primary Cells by Cluster

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.22e-051999951973527f8a7d4c6490d75c0d0ea153688166a08b
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

POLE2 QSOX1 SRGAP1 TAF4B RIOK2

8.22e-0519999533ffea12b8228e0b5bd8942531c3b21d24224725
ToppCellNeuron-Postmitotic-Excitatory_Neuron_|World / Primary Cells by Cluster

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.22e-05199995058373b4ac3cec2108cb24265628ff0a50646e33
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.41e-0520099584e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.41e-052009951decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCellHematolymphoid-Microglia-TYROBP----L1-3|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK10 ST6GAL1 MILR1 SRGAP1 LYN

8.41e-05200995a20dce14f94777687aad57d6fbe3258ad376f63f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM9SF3 DOCK10 ITGB1 SYT11 CLPTM1

8.41e-05200995fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellHematolymphoid-Microglia-TYROBP--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK10 ST6GAL1 MILR1 SRGAP1 LYN

8.41e-05200995dc344b3ec51d506952e38f0b3a7795d65f9dd4eb
ToppCellHematolymphoid-Microglia-TYROBP-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK10 ST6GAL1 MILR1 SRGAP1 LYN

8.41e-052009953bba5219453322198e8fdb0921d5f8c403598751
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Cortical_neuron|3m / Sample Type, Dataset, Time_group, and Cell type.

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.41e-05200995c248233b004f8ef0bab3c65ecfe295887966f2ee
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal|3m / Sample Type, Dataset, Time_group, and Cell type.

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.41e-05200995af99d90070e2933fd2e9512590c6cf3bd6e15539
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PCLO ATAT1 KIDINS220 SRGAP1 MLLT3

8.41e-0520099519055194a5e0ea122f1b8fc62df44813f6843c95
ToppCellHematolymphoid-Microglia|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK10 ST6GAL1 MILR1 SRGAP1 LYN

8.41e-0520099521bcca3b670fe9bac034aef2275d3de4a9a73e2b
ToppCellHematolymphoid-Microglia-TYROBP---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK10 ST6GAL1 MILR1 SRGAP1 LYN

8.41e-05200995a8646d0fca99f10827c2d2a12e584660ef7155f1
ToppCellHematolymphoid-Microglia-TYROBP|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK10 ST6GAL1 MILR1 SRGAP1 LYN

8.41e-0520099533036d21c1c82109284473a515c4f890b33fdd5c
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYT1 CCDC38 SLC6A3 WDR72

9.92e-05108994d620f07243c2628494e689bbfabc14c453f4b1f4
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rprm|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 CPLX3 SVIL GSG1L

1.49e-041209942b7596946f9268c4202348adf3069decd8313bb0
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Mup5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 CPLX3 SVIL GSG1L

1.85e-041279946df92f80b8922ca00eb383f79cd8dda4d602adfc
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_ALM_Olfr111_Spon1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 CPLX3 SVIL GSG1L

1.85e-04127994cd69ba386796715e87674f8324d2acaad1d4d094
ToppCell390C-Lymphocytic-ILC-ILC-1|ILC / Donor, Lineage, Cell class and subclass (all cells)

HPSE VPS13A SF3A2

1.99e-0451993f97523d1cae5932d9a4e8d7f37c202b12e5a0685
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDNF DOCK10 CPLX3 ZNF804B

2.03e-041309948bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DOCK10 COLGALT2 CPLX3 ZNF804B

2.03e-0413099460e28d452d0e2af768459ba8dbe998117c94a251
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SDK2 CPLX3 SVIL GSG1L

2.09e-0413199481efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PROM1 CPLX3 SRGAP1 WDR72

2.09e-041319949ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCell356C-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COLGALT2 NEB HPSE KIDINS220

2.41e-04136994edfd453c9a650d69d05a5a3ab15f7df56349fa86
ToppCell356C-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

COLGALT2 NEB HPSE KIDINS220

2.41e-0413699403e4e2353c23ceffde35b2d0aadd15299e3db09f
ToppCellControl-B_memory-6|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ITGB1 SYT11 DUSP16 WDR72

2.41e-0413699494f23bef50c0beb54ed39b1a4b340f7aec4e75cd
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|healthy_donor / Disease condition, Lineage, Cell class and subclass

HSPG2 SAMD9 POLE2 CUL5

2.54e-0413899497f5dc17522462133e582b508ad0ef036e656872
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDNF DOCK10 CPLX3 ZNF804B

3.32e-041489945e738522d4ad35e08bc4ff8c41b7bea38ec6ef95
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDNF DOCK10 CPLX3 ZNF804B

3.67e-041529948ff5a178a8f3550d89a003c0858820aab3773386
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NDNF DOCK10 PROM1 CPLX3

3.67e-04152994fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

POLE2 MCM5 RRM2 SKA1

3.77e-04153994c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PANX3 TMEM232 SLC28A1 PAPPA

4.15e-041579947fdc0094dd5729990a91a30c1982a14c74650b52
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PANX3 TMEM232 SLC28A1 PAPPA

4.15e-04157994c762b03e254c73222094725ca8ac1c8eb428bccb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PANX3 TMEM232 SLC28A1 PAPPA

4.15e-041579946b5b08bb5520fcf6f4c0560f7ed7645ec179806d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NDNF DOCK10 RRM2 CPLX3

4.35e-0415999472678dfedc152f524fac14ddb31d4fed1528d52a
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCM5 NEB RRM2 SKA1

4.46e-041609945cc1b75e3c20d83112b3aa2f3c749a6c73910a2d
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MCM5 RRM2 MILR1 SKA1

4.57e-041619940dd1401b4c990d49fccb702a9f9867590a58e203
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5-P5_1-Mitotic.MkI67_(Mitotic.MkI67)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MCM5 RRM2 MILR1 SKA1

4.57e-04161994b6a31c033edc74f23a20aab1f18e80cc83ffee4c
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P5|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MCM5 RRM2 MILR1 SKA1

4.57e-04161994efb811dda4d73107983a5f68302bdcf4f408d5b4
Diseaseinterleukin 1 receptor antagonist measurement

TRANK1 IL1F10 PAPPA DNAH11

2.62e-0553954EFO_0004754
Diseaseantihyperlipidemic drug use measurement

TMPRSS11E IL1F10 DNAH11 WDR72

5.30e-04115954EFO_0803367
DiseaseCongenital myopathy (disorder)

NEB SELENON

6.63e-0412952C0270960
Diseaseserum gamma-glutamyl transferase measurement

UNC119B GPATCH1 TMPRSS11E RYR2 IGF1R TRANK1 SYT11 SVIL MLLT3 IFT80

7.27e-049149510EFO_0004532
Diseaseplatelet component distribution width

DOCK9 MYT1 DOCK10 LGALS8 IGF1R TRANK1 SVIL MLLT3 LYN

7.42e-04755959EFO_0007984
DiseaseRespiratory Depression

IGF1R IFT80

7.82e-0413952C0235063
DiseaseRespiratory Insufficiency

IGF1R IFT80

7.82e-0413952C0035229
DiseaseRespiratory Failure

IGF1R IFT80

7.82e-0413952C1145670
DiseaseSchizoaffective disorder-bipolar type

PCLO MYT1

1.20e-0316952EFO_0009965
Diseaseuridine diphosphate galactose measurement, uridine diphosphate glucose measurement

SRBD1 SVIL

1.35e-0317952EFO_0010543, EFO_0010544
Diseaselysophosphatidylcholine 18:1 measurement

FERD3L MPHOSPH10

1.35e-0317952EFO_0010360
DiseaseAge-related macular degeneration

ERCC6 CFB

1.52e-0318952cv:C0242383
Diseasealkaline phosphatase measurement

HSPG2 SAMD9 GPATCH1 TMPRSS11E ST6GAL1 ATAT1 TRANK1 UCKL1 CLPTM1 GSG1L

1.60e-0310159510EFO_0004533
Diseasecerebral microbleeds

HSPG2 SRGAP1

1.69e-0319952EFO_0010059
Diseasecarotid artery disease (is_marker_for)

HSPG2 PAPPA

1.69e-0319952DOID:3407 (is_marker_for)
DiseaseEndometrioma

NDNF ENPP1 ITGB1 PAPPA

1.85e-03161954C0269102
DiseaseEndometriosis

NDNF ENPP1 ITGB1 PAPPA

1.85e-03161954C0014175
DiseaseFetal Growth Retardation

SAMD9 IGF1R

1.88e-0320952C0015934
Diseasehippocampal volume

MCM5 COLGALT2 RYR2 PAPPA DNAH11

2.77e-03297955EFO_0005035
Diseaseblood cadmium measurement

MLLT3 WDR72

3.17e-0326952EFO_0007576
Diseasediabetes mellitus (implicated_via_orthology)

PROM1 IGF1R

3.17e-0326952DOID:9351 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RKTLDPVFDETFTFY

SYT11

216

Q9BT88
DDPRFLTARDKAYKA

CUL5

361

Q93034
NKEEPRKVRFDYDLF

MLLT3

91

P42568
KRKVFEQGYREEPTF

GSG1L

251

Q6UXU4
DYVAFKSKTLEFDRR

DNAH11

536

Q96DT5
AFDIPRFVYNSERKK

POLE2

91

P56282
FSPENTRKELFYKAD

SERPINC1

261

P01008
VYPNDFRLTDKEKSS

DENND6B

61

Q8NEG7
YAPEFETVEETRKKL

RBM48

121

Q5RL73
DAYRKFEIKITFRPD

HSPG2

3681

P98160
IPYSFFKTALDDRKE

QSOX1

366

O00391
TYIRCPSFFDKLTKE

IREB2

716

P48200
FTLKFKRAEDYPIDL

ITGB1

131

P05556
YDKVKDISEVVTPRF

CFB

666

P00751
KTYDEKPVDFLEFRR

ERCC6

971

P0DP91
KESEPSARTKFYFEQ

IL1F10

136

Q8WWZ1
EPIRTFIKAKEYLSD

KIDINS220

1561

Q9ULH0
KVFRSLKYAESDPTV

MBTPS1

131

Q14703
TDRTGFTFKYRDELK

MCM5

46

P33992
ITYDTPFKREKSFEI

LGALS8

91

O00214
SFSSKDEKREDRTPY

FAM13B

556

Q9NYF5
KAEDYRSYRFPKLTV

IGF1R

66

P08069
KRDKYSVFNFLTLPE

GPATCH1

641

Q9BRR8
AFDESPELKYRETKS

PCLO

1636

Q9Y6V0
LFRDTPKRYFFVVEE

NDNF

56

Q8TB73
FRESVEKTIPYSDKL

IMMT

71

Q16891
SRNLKYKDFFDPVES

MPHOSPH10

261

O00566
FSRTPEDFLKKYDEL

TUBGCP2

56

Q9BSJ2
FAKSDRIEPLTFYLD

ENPP1

501

P22413
KDPRYFFSLKTDRAR

PAPPA

166

Q13219
PYRFKKRTELFIAAE

RPL8

66

P62917
FLIFDPKKESTFEER

HPSE

101

Q9Y251
ESRPSRLKKDEYEFF

PAH

66

P00439
ISKYDREPAEFNLTK

MILR1

171

Q7Z6M3
DFTPNRDKKTDYDTR

RBBP6

1466

Q7Z6E9
NELEKARKERYFEFP

PANX3

176

Q96QZ0
YIDFEKIRKALPSSE

OPA1

146

O60313
FRDKYRLPKNETDES

CPLX3

76

Q8WVH0
KEAAEKPRTVFSDYL

CCPG1

556

Q9ULG6
YEEEFLRKSNLKAPS

IFT57

56

Q9NWB7
PKTLYERDASEFSKN

IFT80

546

Q9P2H3
EDPSKSYVKLRDFVL

HAT1

276

O14929
YVTPFFEEKEIEDRK

DOCK10

1951

Q96BY6
KSESRVKLFYLDPDA

DOCK9

331

Q9BZ29
YPSSRLPEFTEEEKK

GBA3

281

Q9H227
FDQLRRKVPTFAYEK

FERD3L

121

Q96RJ6
SLDEAYRFVKEKRPT

DUSP16

266

Q9BY84
VFEKYTTAARTFPDK

CENPJ

976

Q9HC77
KEKAEERPTFDYLQS

LYN

481

P07948
DIKPYSSSDREFLKV

ATAT1

231

Q5SQI0
KDGSTKEDRPYKIFF

CCDC38

16

Q502W7
KEDRPYKIFFRDLFL

CCDC38

21

Q502W7
IDLRKEASDKLTFYP

COLGALT2

241

Q8IYK4
NPDFKVFRYSTSLEK

SART3

786

Q15020
FIVDRLKPFTSYKFR

SDK2

1461

Q58EX2
ELDTPSIEKRFAYSF

RYR2

2911

Q92736
FLRDDDYKTIKSERF

CFAP47

381

Q6ZTR5
KESTRLYPVFFLKID

PMS1

286

P54277
PLKEYSFEKVREESS

LRRC8D

391

Q7L1W4
EEFTRKLYVELKSSP

TAF4B

301

Q92750
KKSASLDVEPIYTFR

STRN3

516

Q13033
DFFRKKAEIETEYSR

SRGAP1

51

Q7Z6B7
RFIDEETKDTKGRYF

SKA1

196

Q96BD8
SETNERLFDEKYKPV

TIMM29

206

Q9BSF4
RLFDEKYKPVVLTDD

TIMM29

211

Q9BSF4
KPDDDETFAKFYRSV

SVIL

1301

O95425
DSFPDTKVTYVDRKE

SYNM

661

O15061
KTSRPSIYELEKEFL

MAP3K21

1021

Q5TCX8
QEDKPDRVYFKSLFR

NXPE3

201

Q969Y0
DISYPVRKETKQDTF

PWWP3B

496

Q5H9M0
YSSPFVKRDKYERLE

SAMD9

701

Q5K651
FPEDTLRKFLQKAYE

PROM1

71

O43490
DIDSRYISPEQKKEF

PRAMEF20

241

Q5VT98
EEFVYEKLDRKAPSR

SH3GLB1

76

Q9Y371
DQVDIYEFLPSKRKT

ST6GAL1

336

P15907
SYVDKNTKDRFPVFS

RD3L

171

P0DJH9
ETPFSREYYEKKREH

SIX6OS1

131

Q8N1H7
YETIAFKVPSREIDK

SF3A2

176

Q15428
DFRTDFDKPDFKRSI

SRBD1

896

Q8N5C6
IFPRLSFKDKSTYIE

CLPTM1

451

O96005
FYKSPLREEFVKSQV

TMPRSS11E

91

Q9UL52
IDEDLSFPSYISRFK

ZNF804B

621

A4D1E1
KLEREFKEYTESSPS

VPS13A

2576

Q96RL7
YVDFFEDPSSERKEK

SNX14

571

Q9Y5W7
DTYIKDPKEREFLFN

RRM2

181

P31350
FLYKKLFSRRDPEED

STAG2

431

Q8N3U4
EAYRELKEDLTPFKD

TMEM181

121

Q9P2C4
SESIFRPVEDKKRYE

TMEM232

236

C9JQI7
SFREKLAYAIAPEKD

SLC6A3

586

Q01959
KKVSYLPFTEAFDRA

SELENON

426

Q9NZV5
KPEDNIYSIDFTRFK

UNC119B

86

A6NIH7
ERKEPFYKVLFSGEV

WDR72

331

Q3MJ13
RFSYESELFPTFKDI

RIOK2

276

Q9BVS4
LSKLVYPEVEESKFR

SLC28A1

381

O00337
DVKFEDRFDKYLDPS

TM9SF3

201

Q9HD45
DKEDDFRAPLYKTVE

ZDHHC5

81

Q9C0B5
PRIKKSTYFSDEEEL

ZCRB1

201

Q8TBF4
RDKETSRDEFIFYSK

UCKL1

341

Q9NWZ5
ADFFYRSLSSELKKP

TRAPPC8

1196

Q9Y2L5
YKPKDVTRAIQDFRF

TRANK1

2466

O15050
KTFVKRNVEFEPTYE

ATP6V0A2

136

Q9Y487
SYYSKDPSRAEKREI

MYT1

426

Q01538
KFKALYTLPRSVDDD

NEB

4746

P20929
ERTKSDFKYVADSPI

NEB

5376

P20929