Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLCO2B1 SLC25A16 SLC1A2 SLC7A14 SLCO1B7 SLCO1A2 SLC22A1 SLC6A20 SLC22A20P SLC38A8	7.05e-06	293	114	10	GO:0008514
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLCO2B1 SLC25A16 SLC1A2 SLC5A3 SLC5A4 SLCO1B7 CLCN3 SLCO1A2 SLC22A1 SLC6A20	7.70e-06	296	114	10	GO:0015291
GeneOntologyMolecularFunction	transporter activity	SLC25A20 SLCO2B1 SIDT1 ABCC9 APOB SLC25A16 SLC1A2 SLC7A14 SLC5A3 SLC5A4 SLCO1B7 SIDT2 CLCN1 CLCN3 SLCO1A2 SLC22A1 SLC6A20 PITPNM3 TRPM1 SLC22A20P SLC38A8	1.15e-05	1289	114	21	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC25A20 SLCO2B1 SIDT1 ABCC9 SLC25A16 SLC1A2 SLC7A14 SLC5A3 SLC5A4 SLCO1B7 SIDT2 CLCN1 CLCN3 SLCO1A2 SLC22A1 SLC6A20 TRPM1 SLC22A20P SLC38A8	3.75e-05	1180	114	19	GO:0022857
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLCO2B1 SLC5A3 SLCO1B7 SLCO1A2 SLC22A1	5.00e-05	70	114	5	GO:1901618
GeneOntologyMolecularFunction	prostaglandin transmembrane transporter activity	SLCO2B1 SLCO1B7 SLC22A1	6.30e-05	14	114	3	GO:0015132
GeneOntologyMolecularFunction	quaternary ammonium group transmembrane transporter activity	SLC25A20 SLC22A1 SLC6A20	7.84e-05	15	114	3	GO:0015651
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	SLCO2B1 SLCO1B7 SLC22A1	7.84e-05	15	114	3	GO:0071714
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLCO2B1 ABCC9 SLC25A16 SLC1A2 SLC5A3 SLC5A4 SLCO1B7 CLCN3 SLCO1A2 SLC22A1 SLC6A20	9.07e-05	477	114	11	GO:0022804
GeneOntologyMolecularFunction	RNA transmembrane transporter activity	SIDT1 SIDT2	9.66e-05	3	114	2	GO:0051033
GeneOntologyMolecularFunction	nucleic acid transmembrane transporter activity	SIDT1 SIDT2	9.66e-05	3	114	2	GO:0051032
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC1A2 SLC5A3 SLC5A4 SLC22A1 SLC6A20	1.01e-04	81	114	5	GO:0015370
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC25A20 SLC1A2 SLCO1A2 SLC22A1 SLC6A20	1.13e-04	83	114	5	GO:0015101
GeneOntologyMolecularFunction	sodium-independent organic anion transmembrane transporter activity	SLCO2B1 SLCO1B7 SLCO1A2	1.39e-04	18	114	3	GO:0015347
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLCO2B1 SLC1A2 SLC7A14 SLCO1B7 SLCO1A2 SLC6A20 SLC38A8	1.87e-04	207	114	7	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLCO2B1 SLC1A2 SLC7A14 SLCO1B7 SLCO1A2 SLC6A20 SLC38A8	1.93e-04	208	114	7	GO:0005342
GeneOntologyMolecularFunction	nucleobase-containing compound transmembrane transporter activity	SIDT1 SLC25A16 SIDT2 SLC22A1	3.60e-04	59	114	4	GO:0015932
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC1A2 SLC5A3 SLC5A4 SLC22A1 SLC6A20	6.05e-04	119	114	5	GO:0015294
GeneOntologyMolecularFunction	D-glucose:sodium symporter activity	SLC5A3 SLC5A4	6.66e-04	7	114	2	GO:0005412
GeneOntologyMolecularFunction	ribosomal protein S6 kinase activity	RPS6KA4 RPS6KA2	6.66e-04	7	114	2	GO:0004711
GeneOntologyMolecularFunction	lipid transmembrane transporter activity	SLCO2B1 SLCO1B7 SLCO1A2 SLC22A1	8.10e-04	73	114	4	GO:0170055
GeneOntologyMolecularFunction	lipid transporter activity	SLCO2B1 APOB SLCO1B7 SLCO1A2 SLC22A1 PITPNM3	9.18e-04	196	114	6	GO:0005319
GeneOntologyMolecularFunction	bile acid transmembrane transporter activity	SLCO2B1 SLCO1B7 SLCO1A2	9.53e-04	34	114	3	GO:0015125
GeneOntologyMolecularFunction	symporter activity	SLC1A2 SLC5A3 SLC5A4 SLC22A1 SLC6A20	1.70e-03	150	114	5	GO:0015293
GeneOntologyMolecularFunction	voltage-gated chloride channel activity	CLCN1 CLCN3	1.72e-03	11	114	2	GO:0005247
GeneOntologyMolecularFunction	monocarboxylic acid transmembrane transporter activity	SLCO2B1 SLC7A14 SLCO1B7 SLCO1A2	1.77e-03	90	114	4	GO:0008028
GeneOntologyBiologicalProcess	organic anion transport	SLC25A20 HTR6 SLCO2B1 SLC25A16 SLC1A2 SLC7A14 PTGS2 SLCO1B7 SLCO1A2 SLC22A1 SLC6A20 SLC22A20P SLC38A8	4.50e-06	515	112	13	GO:0015711
GeneOntologyBiologicalProcess	transport across blood-brain barrier	SLCO2B1 ABCC9 SLC1A2 SLC5A3 SLC22A1 SLC6A20	7.91e-06	87	112	6	GO:0150104
GeneOntologyBiologicalProcess	vascular transport	SLCO2B1 ABCC9 SLC1A2 SLC5A3 SLC22A1 SLC6A20	8.45e-06	88	112	6	GO:0010232
GeneOntologyBiologicalProcess	carboxylic acid transport	SLC25A20 HTR6 SLCO2B1 SLC1A2 SLC7A14 PTGS2 SLCO1B7 SLCO1A2 SLC22A1 SLC6A20 SLC38A8	1.46e-05	410	112	11	GO:0046942
GeneOntologyBiologicalProcess	organic acid transport	SLC25A20 HTR6 SLCO2B1 SLC1A2 SLC7A14 PTGS2 SLCO1B7 SLCO1A2 SLC22A1 SLC6A20 SLC38A8	1.52e-05	412	112	11	GO:0015849
GeneOntologyBiologicalProcess	amino-acid betaine transport	SLC25A20 SLC22A1 SLC6A20	5.43e-05	14	112	3	GO:0015838
GeneOntologyBiologicalProcess	sodium-independent organic anion transport	SLCO2B1 SLCO1B7 SLCO1A2	6.76e-05	15	112	3	GO:0043252
GeneOntologyBiologicalProcess	acyl carnitine transport	SLC25A20 SLC22A1	8.74e-05	3	112	2	GO:0006844
GeneOntologyBiologicalProcess	acyl carnitine transmembrane transport	SLC25A20 SLC22A1	8.74e-05	3	112	2	GO:1902616
GeneOntologyBiologicalProcess	vascular process in circulatory system	SLCO2B1 ABCC9 DBH ITGA9 SLC1A2 PTGS2 SLC5A3 SLC22A1 SLC6A20	1.09e-04	344	112	9	GO:0003018
GeneOntologyBiologicalProcess	organic cation transport	SLC25A20 HTR6 SLC1A2 SLCO1A2 SLC22A1 SLC6A20	1.41e-04	145	112	6	GO:0015695
GeneOntologyBiologicalProcess	quaternary ammonium group transport	SLC25A20 SLC22A1 SLC6A20	1.42e-04	19	112	3	GO:0015697
Domain	SID-1_RNA_chan	SIDT1 SIDT2	3.50e-05	2	111	2	PF13965
Domain	SID1_TM_fam	SIDT1 SIDT2	3.50e-05	2	111	2	IPR025958
Domain	OA_transporter	SLCO2B1 SLCO1B7 SLCO1A2	4.32e-05	12	111	3	IPR004156
Domain	OATP	SLCO2B1 SLCO1B7 SLCO1A2	4.32e-05	12	111	3	PF03137
Domain	Cul7	CUL9 HERC2	1.05e-04	3	111	2	PF11515
Domain	CPH_domain	CUL9 HERC2	1.05e-04	3	111	2	IPR021097
Domain	TFIID-31	TAF9B TAF9	1.05e-04	3	111	2	IPR003162
Domain	TFIID-31kDa	TAF9B TAF9	1.05e-04	3	111	2	PF02291
Domain	ARM-type_fold	TNPO1 UBR4 CUL9 ARMH1 APOB SPAG6 PIK3C2G STAG2 SYMPK	1.92e-04	339	111	9	IPR016024
Domain	Ribosomal_S6_kinase_II	RPS6KA4 RPS6KA2	5.17e-04	6	111	2	IPR016239
Domain	APC_su10/DOC_dom	CUL9 HERC2	7.21e-04	7	111	2	IPR004939
Domain	DOC	CUL9 HERC2	7.21e-04	7	111	2	PS51284
Domain	ANAPC10	CUL9 HERC2	7.21e-04	7	111	2	PF03256
Domain	APC10	CUL9 HERC2	7.21e-04	7	111	2	SM01337
Pathway	REACTOME_TRANSPORT_OF_ORGANIC_ANIONS	SLCO2B1 SLCO1B7 SLCO1A2	5.49e-05	12	91	3	MM15476
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLCO2B1 ACO1 ABCC9 APOB SLC1A2 SLC5A3 SLC5A4 SLCO1B7 CLCN1 SLCO1A2 SLC22A1 SLC6A20 TRPM1 SOAT2	1.12e-04	681	91	14	MM14985
Pathway	WP_TCA_CYCLE_AND_DEFICIENCY_OF_PYRUVATE_DEHYDROGENASE_COMPLEX_PDHC	ACO1 OGDH DLST	1.37e-04	16	91	3	M39489
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	SLCO2B1 SLC1A2 SLC5A3 SLC5A4 SLCO1B7 SLCO1A2 SLC22A1 SLC6A20	1.49e-04	238	91	8	MM15076
Pubmed	Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.	APOB CCKAR SLCO1A2 SLC22A1 SOAT2	5.19e-07	47	116	5	11208732
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	SLCO2B1 ABCC9 SLC1A2 SLC5A3 SLC22A1 SLC6A20	1.49e-06	105	116	6	30280653
Pubmed	Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin.	ACO1 OGDH PTGS2 DLST	9.79e-06	40	116	4	38418556
Pubmed	The Effects of N-Glycosylation on the Expression and Transport Activity of OATP1A2 and OATP2B1.	SLCO2B1 SLCO1A2	1.10e-05	2	116	2	38432624
Pubmed	Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit.	ABCC9 MED23	1.10e-05	2	116	2	11934987
Pubmed	Differential cellular expression of organic anion transporting peptides OATP1A2 and OATP2B1 in the human retina and brain: implications for carrier-mediated transport of neuropeptides and neurosteriods in the CNS.	SLCO2B1 SLCO1A2	1.10e-05	2	116	2	25132355
Pubmed	In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.	TAF9B TAF9	1.10e-05	2	116	2	12837753
Pubmed	A novel family of mammalian transmembrane proteins involved in cholesterol transport.	SIDT1 SIDT2	1.10e-05	2	116	2	28785058
Pubmed	Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation.	OGDH DLST	1.10e-05	2	116	2	22169199
Pubmed	Vlgr1 knockout mice show audiogenic seizure susceptibility.	DBH ADGRV1	1.10e-05	2	116	2	15606908
Pubmed	Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.	SIDT1 SIDT2	1.10e-05	2	116	2	26067272
Pubmed	The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.	CDH23 ADGRV1	1.10e-05	2	116	2	15820310
Pubmed	Localization of Xenobiotic Transporters Expressed at the Human Blood-Testis Barrier.	SLCO2B1 SLCO1A2 SLC22A1	1.96e-05	16	116	3	35307651
Pubmed	Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.	RPS6KA4 TM9SF4 RPS6KA2 BACH2 SANBR SLAMF1 TXK PHTF1	2.04e-05	342	116	8	23128233
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	EFCAB5 AMER1 ZSWIM5 SLCO2B1 UBR4 SANBR APOB OGDH ACTR2 EEF2 STXBP2 CLCN3 DLST STAG2 PHTF1 SYNCRIP	2.45e-05	1442	116	16	35575683
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	SLCO2B1 SLC1A2 SLC5A3 SLC22A1	2.81e-05	52	116	4	26590417
Pubmed	Subunit interactions in the mammalian alpha-ketoglutarate dehydrogenase complex. Evidence for direct association of the alpha-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components.	OGDH DLST	3.30e-05	3	116	2	9727038
Pubmed	The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.	OGDH DLST	3.30e-05	3	116	2	23475850
Pubmed	SLCO1A2, SLCO1B1 and SLCO2B1 polymorphisms influences chloroquine and primaquine treatment in Plasmodium vivax malaria.	SLCO2B1 SLCO1A2	3.30e-05	3	116	2	28975866
Pubmed	Folate-deficiency induced acyl-CoA synthetase short-chain family member 2 increases lysine crotonylome involved in neural tube defects.	ACADS ACSS2	3.30e-05	3	116	2	36743291
Pubmed	Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah.	OGDH DLST	3.30e-05	3	116	2	15466852
Pubmed	Dietary fat-induced alterations in atherosclerosis are abolished by ACAT2-deficiency in ApoB100 only, LDLr-/- mice.	APOB SOAT2	3.30e-05	3	116	2	17431188
Pubmed	LDL particle core enrichment in cholesteryl oleate increases proteoglycan binding and promotes atherosclerosis.	APOB SOAT2	3.30e-05	3	116	2	23804810
Pubmed	Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.	APOB SOAT2	3.30e-05	3	116	2	20231283
Pubmed	Human TAFII31 protein is a transcriptional coactivator of the p53 protein.	TAF9B TAF9	3.30e-05	3	116	2	7761466
Pubmed	Frequencies of single-nucleotide polymorphisms of SLCO1A2, SLCO1B3 and SLCO2B1 genes in a Finnish population.	SLCO2B1 SLCO1A2	3.30e-05	3	116	2	20560925
Pubmed	Structure-function relationships in dihydrolipoamide acyltransferases.	OGDH DLST	3.30e-05	3	116	2	2188967
Pubmed	Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.	BACH2 SLC1A2 HERC2	3.37e-05	19	116	3	22561518
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	RPS6KA4 SANBR CUL9 SLC7A14 ACTR2 HERC2 DNMBP GAA	3.63e-05	371	116	8	15747579
Pubmed	Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.	ACO1 ACSS2 OGDH DLST GAA	4.16e-05	114	116	5	28245920
Pubmed	Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?	HTR6 APOB DBH CCKAR PIK3C2G SOAT2	4.69e-05	192	116	6	20602615
Pubmed	Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.	SLCO1B7 SLCO1A2	6.59e-05	4	116	2	20644253
Pubmed	Digoxin is not a substrate for organic anion-transporting polypeptide transporters OATP1A2, OATP1B1, OATP1B3, and OATP2B1 but is a substrate for a sodium-dependent transporter expressed in HEK293 cells.	SLCO2B1 SLCO1A2	6.59e-05	4	116	2	21849517
Pubmed	KAT2A coupled with the α-KGDH complex acts as a histone H3 succinyltransferase.	OGDH DLST	6.59e-05	4	116	2	29211711
Pubmed	Overexpression of human diacylglycerol acyltransferase 1, acyl-coa:cholesterol acyltransferase 1, or acyl-CoA:cholesterol acyltransferase 2 stimulates secretion of apolipoprotein B-containing lipoproteins in McA-RH7777 cells.	APOB SOAT2	6.59e-05	4	116	2	15308631
Pubmed	Role for a novel Usher protein complex in hair cell synaptic maturation.	CDH23 ADGRV1	6.59e-05	4	116	2	22363448
Pubmed	Interaction of protocadherin-15 with the scaffold protein whirlin supports its anchoring of hair-bundle lateral links in cochlear hair cells.	CDH23 ADGRV1	6.59e-05	4	116	2	33009420
Pubmed	Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.	SLCO1B7 SLCO1A2	6.59e-05	4	116	2	27777271
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TNPO1 UBR4 CUL9 ACTR2 DOCK7 PDCD11 HERC2 STAG2 SYNCRIP SYMPK	6.96e-05	653	116	10	22586326
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	CHL1 COL4A3 ACADS DOCK7 TRPM1 PHTF1	7.31e-05	208	116	6	33230847
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	WASHC4 SANBR AMBRA1 ADGRV1 CDK14 CELSR3 PDCD11 MED23 DNMBP	7.35e-05	529	116	9	14621295
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TPST2 MYO9B RPS6KA2 POLG UBR4 CUL9 AMBRA1 WRAP53 CELSR3 PDCD11 HERC2 DNMBP SYMPK	8.38e-05	1105	116	13	35748872
Pubmed	Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter.	ADGRV1 SLC1A2 HERC2	9.97e-05	27	116	3	34709416
Pubmed	Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain.	ABCC9 PIK3C2G	1.10e-04	5	116	2	9514948
Pubmed	Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition.	SLCO1B7 SLCO1A2	1.10e-04	5	116	2	20837016
Pubmed	Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family.	SLCO2B1 SLCO1A2	1.10e-04	5	116	2	10873595
Pubmed	OATP1A/1B transporters affect irinotecan and SN-38 pharmacokinetics and carboxylesterase expression in knockout and humanized transgenic mice.	SLCO1B7 SLCO1A2	1.10e-04	5	116	2	24194565
Pubmed	Polymorphisms of the nuclear receptor pregnane X receptor and organic anion transporter polypeptides 1A2, 1B1, 1B3, and 2B1 are not associated with breast cancer risk.	SLCO2B1 SLCO1A2	1.10e-04	5	116	2	20635135
Pubmed	Ochratoxin A transport by the human breast cancer resistance protein (BCRP), multidrug resistance protein 2 (MRP2), and organic anion-transporting polypeptides 1A2, 1B1 and 2B1.	SLCO2B1 SLCO1A2	1.10e-04	5	116	2	28532671
Pubmed	Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.	F8 ACTR2	1.10e-04	5	116	2	28827327
Pubmed	Analyses of proteins involved in vesicular trafficking in platelets of mouse models of Hermansky Pudlak syndrome.	CCKAR DOCK7	1.10e-04	5	116	2	10479478
Pubmed	Genome-wide association study of smoking behaviours in patients with COPD.	CDH23 DBH CALN1	1.24e-04	29	116	3	21685187
Pubmed	Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse.	TPST2 ACO1 APOB PTGS2	1.25e-04	76	116	4	8288233
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	DNAH3 RPS6KA4 ZNF862 UBR4 HSPA12B PCDH11X	1.36e-04	233	116	6	37704626
Pubmed	Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.	SLCO1B7 SLCO1A2	1.64e-04	6	116	2	22232210
Pubmed	Expression of CLCN voltage-gated chloride channel genes in human blood vessels.	CLCN1 CLCN3	1.64e-04	6	116	2	10198195
Pubmed	Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase.	RPS6KA4 RPS6KA2	1.64e-04	6	116	2	8688081
Pubmed	NO activation of fos promoter elements requires nuclear translocation of G-kinase I and CREB phosphorylation but is independent of MAP kinase activation.	RPS6KA4 RPS6KA2	1.64e-04	6	116	2	11175347
Pubmed	HERC2 targets the iron regulator FBXL5 for degradation and modulates iron metabolism.	ACO1 HERC2	1.64e-04	6	116	2	24778179
Pubmed	Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.	CDH23 ADGRV1	2.29e-04	7	116	2	20058854
Pubmed	Dense Intra-adipose Sympathetic Arborizations Are Essential for Cold-Induced Beiging of Mouse White Adipose Tissue.	NTRK1 DBH	2.29e-04	7	116	2	28918935
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	SLC25A20 SLCO2B1 TM9SF4 BACH2 CDH23 RIPK4 WRAP53 CDK14 OGDH DNAH17 MED23 SYMPK WDTC1	2.64e-04	1242	116	13	30973865
Pubmed	Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.	CDH23 ADGRV1	3.05e-04	8	116	2	19683999
Pubmed	Two quantitative trait loci affecting progressive hearing loss in 101/H mice.	CDH23 SLC22A1	3.05e-04	8	116	2	16897347
Pubmed	SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.	APOB SEC24D	3.05e-04	8	116	2	23580231
Pubmed	Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters.	SLCO2B1 SLCO1A2	3.05e-04	8	116	2	19129463
Pubmed	CREB is a regulatory target for the protein kinase Akt/PKB.	RPS6KA4 RPS6KA2	3.05e-04	8	116	2	9829964
Pubmed	ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response.	TNPO1 EEF2 SYNCRIP	3.51e-04	41	116	3	30517763
Pubmed	CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.	TNPO1 UBR4 OGDH DLST HERC2	3.73e-04	182	116	5	31067453
Pubmed	Auditory cortex interneuron development requires cadherins operating hair-cell mechanoelectrical transduction.	CDH23 ADGRV1	3.91e-04	9	116	2	28705869
Pubmed	New quantitative trait loci that contribute to cholesterol gallstone formation detected in an intercross of CAST/Ei and 129S1/SvImJ inbred mice.	CCKAR SLCO1A2	3.91e-04	9	116	2	12837957
Pubmed	TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.	TAF9B TAF9	3.91e-04	9	116	2	15899866
Pubmed	Changing expression of chloride channels during preimplantation mouse development.	CLCN1 CLCN3	3.91e-04	9	116	2	23115349
Pubmed	Genome-wide association study of smoking initiation and current smoking.	CDH23 SLC1A2	3.91e-04	9	116	2	19268276
Pubmed	RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development.	SLCO1A2 SLC22A1	3.91e-04	9	116	2	22454430
Pubmed	Steroidogenic enzyme P450c17 is expressed in the embryonic central nervous system.	NTRK1 DBH	3.91e-04	9	116	2	7588260
Pubmed	Association analysis between 12 genetic variants of ten genes and personality traits in a young chinese Han population.	HTR6 DBH	3.91e-04	9	116	2	20464528
Pubmed	Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.	APOB SLCO1A2 TAF9	4.05e-04	43	116	3	18722179
Pubmed	Critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp uptake transporters in mouse livers.	SLCO1B7 SLCO1A2	4.88e-04	10	116	2	18703564
Pubmed	Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.	CDH23 ADGRV1	4.88e-04	10	116	2	24618850
Pubmed	Interactions of HIV-1 viral protein R with host cell proteins.	TNPO1 EEF2	4.88e-04	10	116	2	17586317
Pubmed	Regulation of sympathetic neuron differentiation by endogenous nerve growth factor and neurotrophin-3.	NTRK1 DBH	4.88e-04	10	116	2	18162309
Pubmed	Usher protein functions in hair cells and photoreceptors.	CDH23 ADGRV1	4.88e-04	10	116	2	24239741
Pubmed	Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex.	AMBRA1 SLAMF1	4.88e-04	10	116	2	22493499
Pubmed	A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.	CDH23 ADGRV1	4.88e-04	10	116	2	17329413
Pubmed	Strain background effects and genetic modifiers of hearing in mice.	CDH23 ADGRV1	5.95e-04	11	116	2	16579977
Pubmed	Binding of mouse and human fibulin-2 to extracellular matrix ligands.	COL4A3 FBLN1	5.95e-04	11	116	2	7500359
Pubmed	Quantitative trait locus for seizure susceptibility on mouse chromosome 5 confirmed with reciprocal congenic strains.	CCKAR TXK	5.95e-04	11	116	2	17698926
Pubmed	Sensory ataxia and muscle spindle agenesis in mice lacking the transcription factor Egr3.	COL4A3 NTRK1	5.95e-04	11	116	2	9731539
Pubmed	Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties.	SLCO2B1 SLCO1A2	5.95e-04	11	116	2	14579113
Pubmed	Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data.	CDH23 EEF2 CARD14	7.09e-04	52	116	3	26499835
Pubmed	Identification and characterization of the potential promoter regions of 1031 kinds of human genes.	COL4A3 STXBP2 HERC2	7.09e-04	52	116	3	11337467
Pubmed	The Arp2/3 activator WASH controls the fission of endosomes through a large multiprotein complex.	WASHC4 ACTR2	7.12e-04	12	116	2	19922875
Pubmed	Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.	NTRK1 TRPM1	7.12e-04	12	116	2	19850157
Pubmed	Mediator requirement for both recruitment and postrecruitment steps in transcription initiation.	EEF2 MED23	7.12e-04	12	116	2	15749018
Pubmed	Identification of a novel murine organic anion transporter family member, OAT6, expressed in olfactory mucosa.	SLC22A1 SLC22A20P	8.40e-04	13	116	2	15369770
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	COL4A3 FBLN1	8.40e-04	13	116	2	12682087
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CUL9 CELSR3 MED23 WDTC1	9.66e-04	130	116	4	12421765
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	UBR4 HERC2	9.78e-04	14	116	2	27626314
Pubmed	Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.	RPS6KA4 RPS6KA2	9.78e-04	14	116	2	9687510
Cytoband	Ensembl 112 genes in cytogenetic band chr12p12	ABCC9 SLCO1B7 PIK3C2G SLCO1A2	2.01e-04	113	116	4	chr12p12
Cytoband	10p12.2	OTUD1 SPAG6	2.25e-04	9	116	2	10p12.2
Cytoband	12p12	PIK3C2G SLCO1A2	4.85e-04	13	116	2	12p12
GeneFamily	Solute carriers	SLC25A20 SLCO2B1 SLC25A16 SLC1A2 SLC7A14 SLC5A3 SLC5A4 SLCO1B7 SLCO1A2 SLC22A1 SLC6A20 SLC22A20P SLC38A8	2.81e-08	395	83	13	752
GeneFamily	Chloride voltage-gated channels	CLCN1 CLCN3	9.15e-04	10	83	2	302
GeneFamily	Mitogen-activated protein kinase-activated protein kinases	RPS6KA4 RPS6KA2	1.11e-03	11	83	2	1156
GeneFamily	Dyneins, axonemal	DNAH3 DNAH17	2.71e-03	17	83	2	536
GeneFamily	WD repeat domain containing\|DDB1 and CUL4 associated factors	AMBRA1 WDTC1	3.04e-03	18	83	2	498
Coexpression	LEE_DOUBLE_POLAR_THYMOCYTE	RIPK4 SLAMF1 DNMBP CALN1	6.19e-06	28	113	4	M17534
Coexpression	MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP	AFTPH MYO9B UBR4 SLC25A16 DNAH17	6.69e-06	61	113	5	M1559
ToppCell	367C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	AMER1 BACH2 PTGS2 PIK3R6 SLC22A1 CARD14	3.29e-06	155	116	6	335cd798afbaa0a3a3e1dc558a81cfa32da48983
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 TRMT9B COL4A3 ADGRV1 SLCO1A2 DNAH17	9.66e-06	187	116	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RPS6KA2 ITGA9 HSPA12B F8 SLC5A4 PCDH11X	1.06e-05	190	116	6	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RPS6KA2 ITGA9 HSPA12B SLC5A4 PCDH11X STK38L	1.09e-05	191	116	6	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GAL3ST1 SEC11C RIPK4 ADGRV1 SLC1A2 STXBP2	1.16e-05	193	116	6	5f0eba7b1440beb891d94a288f7f18a4e13c3a88
ToppCell	3'_v3-Lung-Mast\|Lung / Manually curated celltypes from each tissue	NTRK1 ARMH1 ITGA9 PTGS2 ZNF462 PIK3R6	1.19e-05	194	116	6	5e6eb81ddc9d5e22c1297734689f476d5a05bff6
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GAL3ST1 SEC11C RIPK4 ADGRV1 SLC1A2 STXBP2	1.19e-05	194	116	6	413112ee8df7407fd418d57c2ff11aad3a6ec259
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GAL3ST1 SEC11C RIPK4 ADGRV1 SLC1A2 STXBP2	1.19e-05	194	116	6	acd5ba9a097595d4caab4f05440531c65a4aa7bc
ToppCell	3'_v3-Lung-Mast-Mast_cells\|Lung / Manually curated celltypes from each tissue	NTRK1 ARMH1 ITGA9 PTGS2 ZNF462 PIK3R6	1.19e-05	194	116	6	7b7f1714c4a9d9519c4d0e460cb87f2eb82392dd
ToppCell	facs-Lung-nan\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO2B1 ABCC9 ITGA9 SEC24D FBLN1 SIDT2	1.26e-05	196	116	6	b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCell	facs-Lung-nan-3m\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO2B1 ABCC9 ITGA9 SEC24D FBLN1 SIDT2	1.26e-05	196	116	6	787c6cd92035e0b1108c2c086c42a229016e476b
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A3 APOB CELSR3 DNAH17	1.83e-05	60	116	4	28415d543aaccc74d19e1bb92b7e6fa94f97f8f2
ToppCell	367C-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	COL4A3 APOB CELSR3 DNAH17	1.83e-05	60	116	4	71eba0fbef11cfc2b1c525d5f051530750e4fce9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 COL4A3 ADGRV1 SLCO1A2 DNAH17	2.58e-05	133	116	5	f303ab771482281d8793974f9f5279cee09431fe
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACADS SIDT1 ACSS2 SLAMF1 SEC24D	4.44e-05	149	116	5	65778f19599b4955c0a16f0121237656449431fb
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes-Non-classical_monocytes_L.1.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO9B PTGS2 SLC5A3 DNAH17 LILRA5	5.36e-05	155	116	5	77ae0b8d30bc3db4a73fd5340f99691a73d2684f
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 SIDT1 TXK TAF9B SOAT2	6.42e-05	161	116	5	334f540dff3508d451e5e85e8e4e8f3b8d6b74e7
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 SIDT1 TXK TAF9B SOAT2	6.42e-05	161	116	5	81d44438e4be4e68a59247e62f02026301a8a0c5
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Lhx1_(Cajal-retzius)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RIPK4 PIK3C2G TAF9 IQCM	7.23e-05	85	116	4	2c94ff338633c39edb4a3a69a04be33db764c586
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Lhx1_(Cajal-retzius)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	RIPK4 PIK3C2G TAF9 IQCM	7.23e-05	85	116	4	f9e874ae2b3eadf58fbbe7367c5f498a357166ca
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma-7\|TCGA-Kidney / Sample_Type by Project: Shred V9	CHL1 ZNF862 WRAP53 SPAG6 SLC22A20P	7.42e-05	166	116	5	b545de32578047c9ca422354b8992f2d9c9e1cc7
ToppCell	5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TPST2 NTRK1 ARMH1 OPN1SW PIK3R6	7.63e-05	167	116	5	0aa1973141a2437df24c9857cd50ff3dfc7673c0
ToppCell	Sigmoid-Macrophage-Macrophage\|Macrophage / Region, Cell class and subclass	TSPAN15 MYO9B SLCO2B1 ITGA9 PTGS2	7.85e-05	168	116	5	bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCell	Smart-seq2-blood_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	RPS6KA4 ARMH1 STXBP2 DENND4B UNC93B1	8.07e-05	169	116	5	0ee74cc97a2db9cc16dc73424f74747afe13af90
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SIDT1 SLAMF1 TXK CALN1 SLC38A8	8.07e-05	169	116	5	700a3a36c379872585204caa6a6cc269b036ae22
ToppCell	metastatic_Brain-B_lymphocytes-GrB-secreting_B_cells\|metastatic_Brain / Location, Cell class and cell subclass	SIDT1 CDH23 OVOS2 SERPINI1 UNC93B1	8.07e-05	169	116	5	71f6761b9927f352e0ccc221ca373319915f4184
ToppCell	droplet-Kidney-nan-21m-Myeloid-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO2B1 ITGA9 PIK3R6 STK38L LILRA5	8.30e-05	170	116	5	510625bd725d3590cffcd7acd1d42219f6eb1139
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AMER1 TXK PCDH11X TAF9 PHTF1	8.30e-05	170	116	5	65c7ed586e7615203a59999549892ed466a89502
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 TRMT9B ZSWIM5 ABCC9 SERPINI1	9.01e-05	173	116	5	d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRMT9B COL4A3 TPST2 SLC5A3 PIK3C2G	9.01e-05	173	116	5	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	NTRK1 EEF2 SERPINI1 PIK3R6 SOAT2	9.01e-05	173	116	5	1e4afa020fae682521335b440ccd33c16f37156f
ToppCell	facs-Heart-LV-18m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 TRMT9B ZSWIM5 ABCC9 SERPINI1	9.01e-05	173	116	5	3c852ffe22f4a5b632463086b08c669310684e80
ToppCell	10x5'-blood-Lymphocytic_T_CD8-Tnaive/CM_CD8\|blood / Manually curated celltypes from each tissue	ARMH1 OPN1SW TXK EEF2 SLC38A8	9.26e-05	174	116	5	8273de40552d1cca1a8fe3647fd5e4cb4bb70f99
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 EFCAB5 ZSWIM5 ABCC9 SERPINI1	9.26e-05	174	116	5	a0a059bb2a64d7011e206db2ebcdf3eb655a925a
ToppCell	facs-Heart-LV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 EFCAB5 ZSWIM5 ABCC9 SERPINI1	9.26e-05	174	116	5	7cd6f9103133f8d7b90f9ff4b3b0b078cf554542
ToppCell	facs-Heart-RV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 TRMT9B EFCAB5 ABCC9 SERPINI1	9.51e-05	175	116	5	bfac175b79bb7d3d81074a2407c206a7647ee75d
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFTPH RPS6KA2 CDK14 ELF4 LILRA5	9.51e-05	175	116	5	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	saliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACO1 SEC24D SIDT2 UNC93B1 LILRA5	9.51e-05	175	116	5	97616bb5c127284aa9e67bc336dfcf29e137164b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CDH23 ITGA9 SLC1A2 SLC7A14 FBLN1	9.51e-05	175	116	5	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	facs-Heart-RV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN15 TRMT9B EFCAB5 ABCC9 SERPINI1	9.51e-05	175	116	5	c94fb35bbac95123201ca87ca835aecaefc0c490
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPAN15 TRMT9B RPS6KA2 ITGA9 F8	1.00e-04	177	116	5	d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RPS6KA2 ITGA9 HSPA12B SLC5A4 PCDH11X	1.03e-04	178	116	5	5f779a66aa42d1d8e8af17b4a08d5dcc733efd4c
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TRMT9B RPS6KA2 ITGA9 F8 PIK3C2G	1.06e-04	179	116	5	40c65e8623547aeb80f9cd2366e29072467ce069
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCC9 SERPINI1 SLC6A20 PCDH11X SOAT2	1.06e-04	179	116	5	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	RPS6KA2 ITGA9 F8 PTGS2 SLC5A4	1.06e-04	179	116	5	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA9 HSPA12B F8 PTGS2 PIK3C2G	1.06e-04	179	116	5	ec1d7017da325647b629de703135a404bbdc627d
ToppCell	3'-Distal_airway-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RPS6KA4 SIDT1 CDH23 ARMH1 UNC93B1	1.09e-04	180	116	5	6a2366d76276452141db1bd93013a9503525f574
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC11C ADGRV1 SLAMF1 TOMT	1.16e-04	96	116	4	a48235df1f5526ce3ffc4c0c2ba038eb20229c55
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC11C ADGRV1 SLAMF1 TOMT	1.16e-04	96	116	4	0fc179af7370a29b7bd5d81e1302a479ae72f196
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC11C ADGRV1 SLAMF1 TOMT	1.16e-04	96	116	4	c301ecfd67ece8bb12be1b94b614957a58046457
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC11C ADGRV1 SLAMF1 TOMT	1.16e-04	96	116	4	7d402d543ff159c9bb84c00b083e6e18fc0ff786
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 GAL3ST1 SIDT1 SLAMF1 SLC7A14	1.17e-04	183	116	5	876b4f128c2168fdae7488201ff44f19c06c8415
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 GAL3ST1 SIDT1 SLAMF1 SLC7A14	1.17e-04	183	116	5	b190b650e61b1b20baf5e42d04acac82d3fd1400
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	AMER1 TM9SF4 WRAP53 SEC24D MED23	1.17e-04	183	116	5	310ad42b2b5d8ddd01d3a12db338f80ac1f5d08e
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AMER1 TM9SF4 WRAP53 SEC24D MED23	1.17e-04	183	116	5	fef51dcf180e6d4e136362c7e140ec5ef372e6d0
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NTRK1 ABCC9 ARMH1 SEC24D FBLN1	1.23e-04	185	116	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	Control-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	OTUD1 SEC11C ARMH1 CDK14 SEC24D	1.27e-04	186	116	5	a08a50bff4e629588faa22440d57334b1df0e8df
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SEC11C RIPK4 ADGRV1 SLC1A2 PIK3C2G	1.30e-04	187	116	5	c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLCO2B1 OTUD1 PTGS2 UNC93B1 GAA	1.33e-04	188	116	5	3f47395db7e6159fc95810545bad4b6e028464c5
ToppCell	facs-MAT-Fat-3m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 ABCC9 SEC24D FBLN1 SIDT2	1.33e-04	188	116	5	7da9750255efbc5cf9aed7e3105a337fac63b9f0
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 NTRK1 ABCC9 FBLN1 PCDH11X	1.36e-04	189	116	5	f0a2d4ef9896d764971ebbc6952510c128bb76e8
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	TSPAN15 SLCO2B1 ACO1 STXBP2 GAA	1.36e-04	189	116	5	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 NTRK1 ABCC9 FBLN1 PCDH11X	1.36e-04	189	116	5	378f26f751ab4b470948c35dd8347de72dd12ff7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RPS6KA2 SIDT1 SLC5A4 PCDH11X STK38L	1.36e-04	189	116	5	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 TRMT9B COL4A3 ADGRV1 DNAH17	1.40e-04	190	116	5	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	RPS6KA2 ITGA9 F8 PTGS2 SLC5A4	1.40e-04	190	116	5	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CHL1 TRMT9B COL4A3 ADGRV1 DNAH17	1.40e-04	190	116	5	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	myeloid-pDC\|World / Lineage and Cell class	RPS6KA4 SIDT1 CDH23 UNC93B1 CCDC183	1.40e-04	190	116	5	88c42779ce2f817d28e672d83f3f1158581edf73
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RPS6KA2 ITGA9 HSPA12B F8 PTGS2	1.40e-04	190	116	5	6b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SEC11C RIPK4 ADGRV1 SLC1A2 STXBP2	1.43e-04	191	116	5	72dbd2e0fabfca8d6f604df35277d3574739a0b3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZSWIM5 ADGRV1 SLC1A2 PIK3C2G SLC6A20	1.43e-04	191	116	5	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC24D FBLN1 SIDT2 GAA SLC38A8	1.43e-04	191	116	5	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RPS6KA2 ITGA9 HSPA12B SLC5A4 PCDH11X	1.47e-04	192	116	5	bacbaef1f230051335f4433e55db07a161b96b4c
ToppCell	390C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NTRK1 ARMH1 PTGS2 ZNF462 CLCN3	1.47e-04	192	116	5	201d430af1e4fee7bc03baf0aca17db26f6f439a
ToppCell	Fetal_29-31_weeks-Immune-T_lymphocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BACH2 SIDT1 ARMH1 SLAMF1 TXK	1.47e-04	192	116	5	69a2b04f03a1b82d067018379f7b8a116e954040
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SEC11C RIPK4 ADGRV1 SLC1A2 PIK3C2G	1.47e-04	192	116	5	b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCell	390C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	NTRK1 ARMH1 PTGS2 ZNF462 CLCN3	1.47e-04	192	116	5	15c1a0a0d07106118427135f166a1da710bf621a
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFTPH UBR4 ITGA9 F8 HERC2	1.47e-04	192	116	5	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SIDT1 ITGA9 HSPA12B SLC5A4 PCDH11X	1.47e-04	192	116	5	56b021c297a21dff357531f21e2464f85186106d
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	TNPO1 ADGRV1 KLHL11 MED23 STAG2	1.50e-04	193	116	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RPS6KA2 ITGA9 HSPA12B SLC5A4 PCDH11X	1.50e-04	193	116	5	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO9B SLCO2B1 ACO1 ACTR2 GAA	1.50e-04	193	116	5	50c2832de75b6469f649355c6b9a75e910d32db3
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MYO9B SLCO2B1 ACO1 ACTR2 GAA	1.50e-04	193	116	5	222829c30ebe47f0ed1e035897e3cd4be10b2a11
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TSPAN15 SLCO2B1 RPS6KA2 SLC5A4 PIK3R6	1.50e-04	193	116	5	01c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SEC11C DBH RIPK4 ADGRV1 STXBP2	1.54e-04	194	116	5	c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCell	droplet-Lung-nan-21m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 SLCO2B1 ABCC9 FBLN1 PCDH11X	1.54e-04	194	116	5	95dfbd9d9b8a47801edcfc35fb0d685901dcd2f8
ToppCell	severe-B_cell\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHL1 BACH2 CDK14 METTL25B SLC6A20	1.54e-04	194	116	5	2fee6083fb56b16d1f04fd0b92ec622fd26ba3fa
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GAL3ST1 SEC11C RIPK4 SLC1A2 STXBP2	1.54e-04	194	116	5	20f81f457ab0a404600effe8beb91fe73d1cfc10
ToppCell	droplet-Lung-nan-21m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHL1 SLCO2B1 ABCC9 FBLN1 PCDH11X	1.54e-04	194	116	5	2507f6dc7f1fe8b91fe1e24497d26d05afc3cd21
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	UBR4 CUL9 GPKOW TXK SOAT2	1.54e-04	194	116	5	5031f324628ff12a33e84cc52157be4786e0961d
ToppCell	PCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TSPAN15 SLCO2B1 RPS6KA2 SLC5A4 PIK3R6	1.54e-04	194	116	5	53a5e8863d79a052dff0758f389be5ac3883c721
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SEC11C RIPK4 ADGRV1 SLC1A2 PIK3C2G	1.54e-04	194	116	5	c47fc3f716ab091a39c20d7639ac783029589ee5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RPS6KA2 SIDT1 HSPA12B SLC5A4 PCDH11X	1.58e-04	195	116	5	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLCO2B1 RPS6KA2 HSPA12B F8 PIK3C2G	1.58e-04	195	116	5	36d4a11bc77a4cc97a22525c78ef8359f4a3ca66
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	GAL3ST1 SEC11C ADGRV1 SLC1A2 STXBP2	1.58e-04	195	116	5	b78db0d929be6b04055805ea5ffecc56c47ba956
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 TPST2 SLC7A14 SLC5A3 PIK3C2G	1.58e-04	195	116	5	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RPS6KA4 SIDT1 CDH23 UNC93B1 CCDC183	1.58e-04	195	116	5	06051de72b5c1e0d483a28b14dabd247dfca0ed9
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RPS6KA4 SIDT1 CDH23 UNC93B1 CCDC183	1.58e-04	195	116	5	3aa44633c72658545aa2b35bf9d532c62f36a451
ToppCell	severe-B_cell\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHL1 BACH2 CDK14 METTL25B SLC6A20	1.58e-04	195	116	5	0fc3c605609c9e6bdea15d73c45def2188ae5fb1
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|GI_small-bowel / Manually curated celltypes from each tissue	TXK SLC5A3 EEF2 PIK3R6 PHTF1	1.62e-04	196	116	5	5755ca4abcae3717894bbf7cbd49bca0a3a03067
Drug	Trimethoprim [738-70-5]; Down 200; 13.8uM; PC3; HT_HG-U133A	MYO9B ZNF862 RPS6KA2 POLG F8 PTGS2 FBLN1 SERPINI1 ELF4	6.43e-07	196	114	9	7377_DN
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; MCF7; HT_HG-U133A	MYO9B RPS6KA2 SLC5A3 SEC24D DNAH17 ELF4 SOAT2 SYMPK	7.11e-06	198	114	8	5259_DN
Drug	Mianserine hydrochloride [21535-47-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	TPST2 DNAH3 F8 SIDT2 CLCN3 CELSR3 ELF4 PHTF1	7.11e-06	198	114	8	6260_DN
Disease	Celiac Disease	MYO9B BACH2 APOB SOAT2	3.09e-05	47	112	4	C0007570
Disease	bilirubin measurement	TNPO1 MYO9B ABCC9 APOB SLCO1B7 SLCO1A2 SLC22A1 DOCK7 DNMBP	4.93e-05	442	112	9	EFO_0004570
Disease	Bipolar Disorder	ACADS NTRK1 RPS6KA2 POLG DBH ITGA9 SLC1A2 CCKAR SLC5A3	8.82e-05	477	112	9	C0005586
Disease	X-23756 measurement	SLCO1B7 SLCO1A2	1.42e-04	5	112	2	EFO_0022126
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	APOB OGDH DOCK7 LILRA5 SOAT2	2.28e-04	144	112	5	EFO_0004611, EFO_0020943
Disease	MASA syndrome (implicated_via_orthology)	CHL1 TRPM1	2.96e-04	7	112	2	DOID:0060246 (implicated_via_orthology)
Disease	Glioma	NTRK1 PTGS2 CLCN3 STAG2	3.44e-04	87	112	4	C0017638
Disease	butyrylcarnitine (C4) measurement	ACADS SLC22A1	3.94e-04	8	112	2	EFO_0800201
Disease	butyrylcarnitine measurement	ACADS SLC22A1	3.94e-04	8	112	2	EFO_0020010
Disease	sleep duration, low density lipoprotein cholesterol measurement	APOB OGDH SLC22A1 DOCK7	4.08e-04	91	112	4	EFO_0004611, EFO_0005271
Disease	Mood Disorders	HTR6 POLG DBH SLC1A2 PTGS2	4.63e-04	168	112	5	C0525045
Disease	cholesterol in very small VLDL measurement	APOB SLC22A1 DOCK7	4.75e-04	40	112	3	EFO_0022231
Disease	hexadecenedioate (C16:1-DC) measurement	SLCO1B7 SLCO1A2	5.05e-04	9	112	2	EFO_0800562
Disease	lysophosphatidylethanolamine measurement	TMEM86B SLCO1B7 SLCO1A2	5.11e-04	41	112	3	EFO_0010225
Disease	phosphatidylethanolamine measurement	TMEM86B ABCC9 APOB SIDT2 SLC38A8	5.29e-04	173	112	5	EFO_0010228
Disease	Schizophrenia	CHL1 HTR6 MYO9B NTRK1 AMBRA1 SLC1A2 PTGS2 ACTR2 CCKAR SERPINI1 TRPM1	5.45e-04	883	112	11	C0036341
Disease	cholesteryl esters to total lipids in small LDL percentage	APOB DOCK7 SOAT2	5.49e-04	42	112	3	EFO_0022255
Disease	pancreatic cancer (is_marker_for)	SLCO2B1 NTRK1 PTGS2 CCKAR	6.05e-04	101	112	4	DOID:1793 (is_marker_for)
Disease	cholesterol in medium VLDL measurement	APOB SLC22A1 DOCK7	6.29e-04	44	112	3	EFO_0022225
Disease	Asthma, Occupational	PTGS2 HERC2	6.30e-04	10	112	2	C0264423
Disease	hair colour measurement, eye colour measurement, skin pigmentation measurement	SERPINI1 HERC2	6.30e-04	10	112	2	EFO_0007009, EFO_0007822, EFO_0009764
Disease	total lipids in very small VLDL measurement	APOB SLC22A1 DOCK7	6.73e-04	45	112	3	EFO_0022156
Disease	free cholesterol in small VLDL measurement	APOB SLC22A1 DOCK7	7.64e-04	47	112	3	EFO_0022272
Disease	free cholesterol in very small VLDL measurement	APOB SLC22A1 DOCK7	7.64e-04	47	112	3	EFO_0022275
Disease	free cholesterol in medium VLDL measurement	APOB SLC22A1 DOCK7	7.64e-04	47	112	3	EFO_0022269
Disease	glycerophospholipid measurement	GAL3ST1 SIDT2 DOCK7	8.64e-04	49	112	3	EFO_0007630
Disease	phospholipids in very small VLDL measurement	APOB SLC22A1 DOCK7	9.71e-04	51	112	3	EFO_0022300
Disease	phospholipids in IDL measurement	APOB SLC22A1 DOCK7	1.03e-03	52	112	3	EFO_0022164
Disease	glycochenodeoxycholate glucuronide (1) measurement	SLCO1B7 SLCO1A2	1.08e-03	13	112	2	EFO_0800474
Disease	cholesteryl esters to total lipids in very large VLDL percentage	APOB SLC22A1 DOCK7	1.09e-03	53	112	3	EFO_0022258
Disease	glycoprotein measurement	APOB ADGRV1 SLC22A1 DOCK7	1.12e-03	119	112	4	EFO_0004555
Disease	triglycerides in chylomicrons and extremely large VLDL measurement	APOB SLC22A1 DOCK7	1.27e-03	56	112	3	EFO_0022316
Disease	triglycerides to total lipids in chylomicrons and extremely large VLDL percentage	APOB SLC22A1	1.45e-03	15	112	2	EFO_0022328
Disease	asthma (biomarker_via_orthology)	NTRK1 PTGS2 SLC22A1	1.48e-03	59	112	3	DOID:2841 (biomarker_via_orthology)
Disease	Cardiomyopathies	POLG ABCC9 PTGS2 GAA	1.55e-03	130	112	4	C0878544
Disease	phospholipids in small VLDL measurement	APOB SLC22A1 DOCK7	1.56e-03	60	112	3	EFO_0022146
Disease	total lipids in IDL	APOB SLC22A1 DOCK7	1.56e-03	60	112	3	EFO_0022161
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	APOB SLC22A1 DOCK7	1.63e-03	61	112	3	EFO_0008317, EFO_0008596, EFO_0020946
Disease	triglycerides in small HDL measurement	APOB SLC22A1 DOCK7	1.71e-03	62	112	3	EFO_0022158
Disease	phospholipids in large VLDL measurement	APOB SLC22A1 DOCK7	1.71e-03	62	112	3	EFO_0022169
Disease	total lipids in chylomicrons and extremely large VLDL measurement	APOB SLC22A1 DOCK7	1.71e-03	62	112	3	EFO_0022306
Disease	phospholipids:total lipids ratio	APOB SLC22A1 DOCK7 LILRA5 SOAT2	1.77e-03	227	112	5	EFO_0020946
Disease	diabetic neuropathy (biomarker_via_orthology)	NTRK1 PTGS2	1.87e-03	17	112	2	DOID:9743 (biomarker_via_orthology)
Disease	X-21441 measurement	SLCO1B7 DNMBP	1.87e-03	17	112	2	EFO_0800814
Disease	cholesterol to total lipids in chylomicrons and extremely large VLDL percentage	APOB SLC22A1	1.87e-03	17	112	2	EFO_0022232
Disease	triglycerides in small LDL measurement	APOB SLC22A1 DOCK7	1.96e-03	65	112	3	EFO_0022323
Disease	free cholesterol in large VLDL measurement	APOB SLC22A1 DOCK7	2.23e-03	68	112	3	EFO_0022265
Disease	sensorineural hearing loss (implicated_via_orthology)	SLC7A14 DNAH17	2.34e-03	19	112	2	DOID:10003 (implicated_via_orthology)
Disease	Malignant Glioma	NTRK1 PTGS2 CLCN3	2.42e-03	70	112	3	C0555198
Disease	mixed gliomas	NTRK1 PTGS2 CLCN3	2.42e-03	70	112	3	C0259783
Disease	urinary metabolite measurement	ACADS RPS6KA2 SLCO1A2 SLC22A1 SLC6A20	2.47e-03	245	112	5	EFO_0005116
Disease	Manic Disorder	NTRK1 RPS6KA2 SLC5A3	2.52e-03	71	112	3	C0024713
Disease	low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	APOB SLCO1A2 DOCK7 SOAT2	2.80e-03	153	112	4	EFO_0004611, EFO_0020944
Disease	Hirschsprung disease	SLC6A20 CARD14	2.86e-03	21	112	2	MONDO_0018309
Disease	fumarate measurement	RPS6KA2 ITGA9	2.86e-03	21	112	2	EFO_0010480
Disease	cholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage	APOB SLC22A1	2.86e-03	21	112	2	EFO_0022246
Disease	cholesteryl ester measurement	APOB SIDT2 SLC22A1 DOCK7 LILRA5	3.03e-03	257	112	5	EFO_0010351
Disease	serum metabolite measurement	TNPO1 TSPAN15 ACADS ZNF862 TMEM86B APOB SLCO1A2 SLC22A1 DNAH17 DOCK7	3.23e-03	945	112	10	EFO_0005653
Disease	Manic	NTRK1 RPS6KA2 SLC5A3	3.29e-03	78	112	3	C0338831
Disease	Depression, Bipolar	NTRK1 RPS6KA2 SLC5A3	3.41e-03	79	112	3	C0005587
Disease	nephrotic syndrome (biomarker_via_orthology)	APOB SOAT2	3.73e-03	24	112	2	DOID:1184 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
SMVLPQVIGYRLMGK	ACO1	236	P21399
LMGDGMYNQVRPQIK	BACH2	566	Q9BYV9
GLVVMPPAMLNALYG	HTR6	76	P50406
MNMAPITGRALEPYI	COL4A3	1531	Q01955
ILGGMGYVTEMPAER	ACADS	366	P16219
QPVIVPMYAAGLGML	AFTPH	746	Q6ULP2
LYLRVVRGLMAAMGN	ARMH1	321	Q6PIY5
MLVGGRFYGMPTILQ	ADGRV1	4856	Q8WXG9
VLEYQMRPLGPSVMG	AMER1	651	Q5JTC6
QIPEYSMGQARALMG	DNMBP	141	Q6XZF7
AMPVQIIMGVILLYN	ABCC9	436	O60706
IFVEMIQGVAAFPGM	CDK14	321	O94921
ILFLIPGIVMMVAYG	CCKAR	216	P32238
PGIVMMVAYGLISLE	CCKAR	221	P32238
GIQKGDRVAIYMPMI	ACSS2	156	Q9NR19
PMGRYVMVGLASRRI	AMBRA1	951	Q9C0C7
GYMPSEVELAIIMQR	CALN1	111	Q9BXU9
LNGLVSYRMPVGMPR	CDH23	921	Q9H251
SMLEVNYPMENGIVR	ACTR2	66	P61160
NGAMMIRIFPYGAIQ	SLC25A16	96	P16260
GPDMKAVINMYGRLI	IQCM	321	A0A1B0GVH7
LLEMMLYAGLPELSG	PIK3C2G	1116	O75747
AGYPELLAMGQMLNV	OTUD1	376	Q5VV17
EGRPLLMVFEYMRHG	NTRK1	581	P04629
YAVENLIRMGMAGLI	LILRA5	261	A6NI73
VMLESLGRPTQEYVM	MAGEE2	391	Q8TD90
QEYVMPILGLIFLMG	MAGEE2	401	Q8TD90
MEPLLLGRGLIVYLM	CHL1	1	O00533
YVQGMVTGAPMEGLL	ELF4	546	Q99607
IMYARDAVVGALMPA	HERC2	3406	O95714
LRLMMDPLTGLNRGY	SYNCRIP	191	O60506
TIVPKMLVDYLMGEG	OR2T6	76	Q8NHC8
PMGALVETIYGNGIM	MED23	491	Q9ULK4
RLQGQMPALMRVGIF	DDX28	426	Q9NUL7
PVTLAGMLEMGVSYL	POLG	421	P54098
LYRGMAAPIIGVTPM	SLC25A20	71	O43772
EVFGLVPGLMMYATI	PTGS2	276	P35354
AVPVEAYGLAMLRGM	GPKOW	161	Q92917
NGYIMDTLPGLVMAQ	F8	1941	P00451
GVILYMMLSGQVPFQ	RPS6KA4	596	O75676
TMLLGMPGEGEVVRY	METTL25B	66	Q96FB5
LPVYLVSLLGNMGMA	OR5C1	36	Q8NGR4
DGGLMPARAMVLVNV	PCDH11X	331	Q9BZA7
AMQNLVVLQMPYGGG	OVOS2	946	Q6IE36
MLAVPEMGLQGLYIG	HSPA12B	1	Q96MM6
IGGKVEVRPMMYVAL	DLST	406	P36957
YMDGMTVGVVRQVRP	FBLN1	651	P23142
QMPRVYFVLLGETMG	ITGA9	526	Q13797
GVDYVIMGMPHRGRL	OGDH	301	Q02218
RRMLTPEIQYLMDLG	GAL3ST1	391	Q99999
DYVLRNMMVTGQLGL	EFCAB5	1196	A4FU69
YLILRVIGNMGQTME	APOB	486	P04114
LPRYGQNMDVIMVIG	KLHL11	351	Q9NVR0
QMALRPGTQIVMVDY	CARD14	606	Q9BXL6
ARVAMLYLPLIGIIM	DOCK7	1236	Q96N67
YMCGGLMERPLILAE	DNAH17	526	Q9UFH2
YMRMLENALQLGTPV	DNAH3	3111	Q8TD57
RQLGMYMVTVIIGLI	SLC1A2	311	P43004
NAGIMELGLVYTPVM	DBH	361	P09172
IQMGIDNLYVRLMGI	CCDC183	406	Q5T5S1
LHQGGRRYMMIVDPA	GAA	431	P10253
YGQPVLSVRVMLEMR	DENND4B	826	O75064
QTLQPGMRVRMLDDY	CUL9	381	Q8IWT3
PIQRTILMMGRYVEP	EEF2	446	P13639
ARNMELTYLNPMGLV	CELSR3	2306	Q9NYQ7
LAGLMVIANMFVPEG	SLC22A20P	406	A6NK97
GRIYPMAMSNLLAGA	SLC22A1	401	O15245
GMIAISRMAVLYPQV	SERPINI1	356	Q99574
MGTVFLIGFPLNAMV	OPN1SW	41	P03999
MGITEYEPRVINQML	TAF9B	26	Q9HBM6
MGITEYEPRVINQML	TAF9	26	Q16594
SGPLYVDRMVLLVMG	SIDT2	681	Q8NBJ9
KGNTRLPGIMMLGYV	SPAG6	306	O75602
GFLPYVGMVTIIMND	SEC11C	156	Q9BY50
RNLYLIMEFLPGGDM	STK38L	161	Q9Y2H1
GEQVEYAEMVPVLRM	WRAP53	206	Q9BUR4
EMAVPGTLYQRMVIA	PIK3R6	126	Q5UE93
YAGLLGGVIMILIMV	SLAMF1	241	Q13291
VPIIVEMQGGQMYLY	SLC5A3	426	P53794
YPTMVLELMPQGLRG	SLC5A4	366	Q9NY91
LMWVYVLVGNIVRGM	SLCO1A2	156	P46721
YVFMGNMLRGIGETP	SLCO1B7	126	G3V0H7
MSYPGNDMVIIVARV	SLC38A8	286	A6NNN8
NQMVLDMILYPLIGI	SANBR	16	Q6NSI8
GICREPVGLVMEYME	RIPK4	86	P57078
MPLLYLELAVGQRMR	SLC6A20	56	Q9NP91
EVGNPYSQQLRMIMG	SEC24D	961	O94855
YPVMLILFLVIGGML	SOAT2	446	O75908
RLVGEIMAMLFPDGI	CLCN1	496	P35523
TGGLEYIVPLMAAVM	CLCN3	601	P51790
PNMETGMIYVVQGIY	UFSP2	271	Q9NUQ7
PMPRVIYAMAGDGLL	SLC7A14	356	Q8TBB6
YGMLVKVGEQMRGLV	PDCD11	466	Q14690
RDMAQIAPMLAQLGY	TPST2	311	O60704
NADPLEVMLLNMGYR	WDTC1	636	Q8N5D0
LMGLGQQRLMPEGLY	ZSWIM5	666	Q9P217
MLMGINVTPIAALLY	UNC93B1	111	Q9H1C4
YMNRFVGILMAGILP	TM9SF4	496	Q92544
LYLMMPIVNISEVLG	PHTF1	116	Q9UMS5
YLGILFAVTMMGPGL	SLCO2B1	226	O94956
QIMSGGRDMLEPLVY	STAG2	801	Q8N3U4
YLSHMGPVKGQILMR	TOMT	111	Q8WZ04
SRPLYMDRMVLLVVG	SIDT1	676	Q9NXL6
GPRLIVYVMGGVAMS	STXBP2	531	Q15833
MYILGICLIMELIGG	TSPAN15	96	O95858
DMVLPVAAYGLILMA	TMEM86B	146	Q8N661
GEISIQMGIEMQPYI	TNPO1	741	Q92973
LVGRFMYGPLDMVAL	PITPNM3	651	Q9BZ71
LTMYPRLGGFVMNIL	SYMPK	1006	Q92797
VMRMNYELLASLGPA	ZNF862	361	O60290
MIGAILRLQNQPYMG	TRPM1	911	Q7Z4N2
AGLMTRLRYPVGLMG	TXK	236	P42681
ISQIGNAMGYVRMIR	WASHC4	916	Q2M389
EMARVLVPGGQLMIY	TRMT9B	126	Q9P272
LVPGGQLMIYVWAME	TRMT9B	131	Q9P272
YIRQAPPTAAMMRGV	ZNF462	1146	Q96JM2
VGGVRAIPYMQVILM	UBR4	2991	Q5T4S7
EPMRIVYRMRGLLGD	UBR4	4436	Q5T4S7
FVYLVMELMRGGELL	RPS6KA2	481	Q15349
NMDYMRPDIVALLRG	MYO9B	651	Q13459