Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	multi-pass transmembrane protein insertion into ER membrane	NOMO2 NOMO3 NOMO1	3.10e-06	9	70	3	GO:0160063
GeneOntologyBiologicalProcess	presynaptic active zone organization	ERC1 PCLO PCDH17	4.42e-06	10	70	3	GO:1990709
GeneOntologyBiologicalProcess	ubiquitin-dependent protein catabolic process via the N-end rule pathway	UBR4 UBR3	6.78e-05	4	70	2	GO:0071596
GeneOntologyBiologicalProcess	presynaptic active zone assembly	PCLO PCDH17	1.13e-04	5	70	2	GO:1904071
GeneOntologyBiologicalProcess	protein insertion into ER membrane	NOMO2 NOMO3 NOMO1	1.57e-04	31	70	3	GO:0045048
GeneOntologyBiologicalProcess	maintenance of presynaptic active zone structure	ERC1 PCLO	1.69e-04	6	70	2	GO:0048790
GeneOntologyCellularComponent	multi-pass translocon complex	NOMO2 NOMO3 NOMO1	3.38e-06	9	73	3	GO:0160064
GeneOntologyCellularComponent	ER membrane insertion complex	NOMO2 NOMO3 NOMO1	1.45e-05	14	73	3	GO:0072379
GeneOntologyCellularComponent	GABA-ergic synapse	CACNA1E CACNA2D2 ERC1 PCLO PCDH17	2.73e-04	164	73	5	GO:0098982
GeneOntologyCellularComponent	cytoskeleton of presynaptic active zone	ERC1 PCLO	3.32e-04	8	73	2	GO:0048788
GeneOntologyCellularComponent	presynaptic membrane	CACNA1E NPY1R CACNA2D2 PODXL ERC1 PCDH17	4.15e-04	277	73	6	GO:0042734
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1E CACNA2D2 RYR1	5.57e-04	46	73	3	GO:0005891
GeneOntologyCellularComponent	synaptic membrane	CACNA1E NPY1R ANK3 CACNA2D2 PODXL ERC1 LRRC4 PCDH17	9.54e-04	583	73	8	GO:0097060
GeneOntologyCellularComponent	presynaptic cytoskeleton	ERC1 PCLO	1.07e-03	14	73	2	GO:0099569
MousePheno	enhanced fertility	RBM44 NPY1R MUC16	6.27e-05	20	55	3	MP:0010143
MousePheno	increased litter size	RBM44 NPY1R MUC16	6.27e-05	20	55	3	MP:0001934
Domain	DUF2012	NOMO2 NOMO3 NOMO1	2.10e-07	4	71	3	PF09430
Domain	DUF2012	NOMO2 NOMO3 NOMO1	2.10e-07	4	71	3	IPR019008
Domain	Carb-bd-like_fold	NOMO2 NOMO3 NOMO1	2.91e-06	8	71	3	IPR013784
Domain	CarboxyPept_regulatory_dom	NOMO2 NOMO3 NOMO1	1.47e-05	13	71	3	IPR014766
Domain	-	NOMO2 NOMO3 NOMO1	1.47e-05	13	71	3	2.60.40.1120
Domain	CarboxyPept-like_regulatory	NOMO2 NOMO3 NOMO1	3.45e-05	17	71	3	IPR008969
Domain	ZF_UBR	UBR4 UBR3	2.96e-04	7	71	2	PS51157
Domain	zf-UBR	UBR4 UBR3	2.96e-04	7	71	2	PF02207
Domain	Znf_UBR	UBR4 UBR3	2.96e-04	7	71	2	IPR003126
Domain	ZnF_UBR1	UBR4 UBR3	2.96e-04	7	71	2	SM00396
Domain	Helicase_C	DDX31 DHX40 SHPRH DHX57	7.37e-04	107	71	4	PF00271
Domain	HELICc	DDX31 DHX40 SHPRH DHX57	7.37e-04	107	71	4	SM00490
Domain	Helicase_C	DDX31 DHX40 SHPRH DHX57	7.63e-04	108	71	4	IPR001650
Domain	HELICASE_CTER	DDX31 DHX40 SHPRH DHX57	7.90e-04	109	71	4	PS51194
Domain	HELICASE_ATP_BIND_1	DDX31 DHX40 SHPRH DHX57	7.90e-04	109	71	4	PS51192
Domain	DEXDc	DDX31 DHX40 SHPRH DHX57	7.90e-04	109	71	4	SM00487
Domain	Helicase_ATP-bd	DDX31 DHX40 SHPRH DHX57	8.17e-04	110	71	4	IPR014001
Domain	HSP70	HSPA6 HSPA7	1.65e-03	16	71	2	PF00012
Domain	HSP70_2	HSPA6 HSPA7	1.87e-03	17	71	2	PS00329
Domain	DUF1605	DHX40 DHX57	1.87e-03	17	71	2	IPR011709
Domain	HSP70_3	HSPA6 HSPA7	1.87e-03	17	71	2	PS01036
Domain	OB_NTP_bind	DHX40 DHX57	1.87e-03	17	71	2	PF07717
Domain	HSP70_1	HSPA6 HSPA7	1.87e-03	17	71	2	PS00297
Domain	HA2	DHX40 DHX57	2.10e-03	18	71	2	SM00847
Domain	HA2	DHX40 DHX57	2.10e-03	18	71	2	PF04408
Domain	Helicase-assoc_dom	DHX40 DHX57	2.10e-03	18	71	2	IPR007502
Domain	Hsp_70_fam	HSPA6 HSPA7	2.10e-03	18	71	2	IPR013126
Domain	DEAD/DEAH_box_helicase_dom	DDX31 DHX40 DHX57	2.71e-03	73	71	3	IPR011545
Domain	DEAD	DDX31 DHX40 DHX57	2.71e-03	73	71	3	PF00270
Domain	Cys-rich_flank_reg_C	IGSF10 TLR1 LRRC4	4.88e-03	90	71	3	IPR000483
Domain	LRRCT	IGSF10 TLR1 LRRC4	4.88e-03	90	71	3	SM00082
Pubmed	Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.	NOMO2 NOMO3 NOMO1	8.87e-09	3	73	3	36011023
Pubmed	Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.	NOMO2 NOMO3 NOMO1	8.87e-09	3	73	3	25576386
Pubmed	Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.	NOMO2 NOMO3 NOMO1	3.54e-08	4	73	3	31833031
Pubmed	A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.	NOMO2 NOMO3 NOMO1	3.54e-08	4	73	3	9267806
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CEP350 SEPTIN8 SYNRG HBS1L MGST1 NOMO2 WASHC5 ERC1 DHX40 MCCC1 ARFIP2 EMSY	2.05e-07	853	73	12	28718761
Pubmed	Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.	NOMO2 NOMO3 NOMO1	4.93e-07	8	73	3	15257293
Pubmed	Substrate-driven assembly of a translocon for multipass membrane proteins.	NOMO2 NOMO3 NOMO1	7.38e-07	9	73	3	36261522
Pubmed	An ER translocon for multi-pass membrane protein biogenesis.	NOMO2 NOMO3 NOMO1	1.45e-06	11	73	3	32820719
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SCYL2 SYNRG HBS1L ANK3 ERC1 NFRKB HSPA6 SNX1 EMSY	2.26e-06	549	73	9	38280479
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	NOMO2 PRCC ERC1 PCLO NFRKB ARFIP2 NOMO3 NOMO1	3.13e-06	425	73	8	24999758
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	NOMO2 ERC1 AKAP11 NOMO3 NOMO1	3.65e-06	110	73	5	27889896
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	CASP8AP2 SYNRG DDX31 NOMO2 ERC1 DHX40 MACF1 MCCC1 EMSY	3.94e-06	588	73	9	38580884
Pubmed	The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1.	HSPA6 HSPA7	4.35e-06	2	73	2	1346391
Pubmed	The 3'UTR of the pseudogene CYP4Z2P promotes tumor angiogenesis in breast cancer by acting as a ceRNA for CYP4Z1.	CYP4Z2P CYP4Z1	4.35e-06	2	73	2	25701119
Pubmed	The competing endogenous RNA network of CYP4Z1 and pseudogene CYP4Z2P exerts an anti-apoptotic function in breast cancer.	CYP4Z2P CYP4Z1	4.35e-06	2	73	2	28236635
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	4.35e-06	2	73	2	23544943
Pubmed	Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma.	CYP4Z2P CYP4Z1	4.35e-06	2	73	2	15059886
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	SCYL2 MGST1 NOMO2 PODXL AKAP11 MCCC1 ARFIP2 TMEM38B SNX1 NOMO3 NOMO1	4.62e-06	952	73	11	38569033
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	CEP350 SYNRG HBS1L ERC1 MACF1 AKAP11	5.34e-06	209	73	6	36779422
Pubmed	Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.	NOMO2 EMSY NOMO3 NOMO1	9.69e-06	63	73	4	31266804
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	CEP350 HBS1L WASHC5 ERC1 AKAP11 MCCC1	1.23e-05	242	73	6	34011540
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	1.30e-05	3	73	2	23053434
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	1.30e-05	3	73	2	30236127
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	1.30e-05	3	73	2	35879412
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC4	1.30e-05	3	73	2	17592322
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC4	1.30e-05	3	73	2	27483328
Pubmed	MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.	MUC16 MUC4	1.30e-05	3	73	2	24204560
Pubmed	Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells.	CYP4Z2P CYP4Z1	1.30e-05	3	73	2	30832689
Pubmed	Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.	MUC16 MUC4	1.30e-05	3	73	2	24939955
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SCYL2 CEP350 CCDC13 ANK3 PDGFRB NOMO2 ERC1 UBR4 MACF1 SKIL LRRC4 SNX1	1.41e-05	1285	73	12	35914814
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	CEP350 ANK3 WASHC5 ERC1 AKAP11 FBXO30	1.51e-05	251	73	6	29778605
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	CEP350 SEPTIN8 SYNRG MGST1 ERC1 MACF1 DHX57 MCCC1 THOC5	2.07e-05	724	73	9	36232890
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SEPTIN8 SYNRG ANK3 WASHC5 ERC1 PCLO UBR4 UBR3 MACF1 MCCC1 SNX1	2.46e-05	1139	73	11	36417873
Pubmed	Distinct kinetic and mechanical properties govern mucin 16- and podocalyxin-mediated tumor cell adhesion to E- and L-selectin in shear flow.	PODXL MUC16	2.60e-05	4	73	2	26329844
Pubmed	TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.	MUC16 MUC4	2.60e-05	4	73	2	39024979
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SCYL2 IGSF10 FSIP2 TSGA10 CCDC7	2.85e-05	168	73	5	30631154
Pubmed	Hepatic lipase maturation: a partial proteome of interacting factors.	NOMO2 NOMO3 NOMO1	3.82e-05	31	73	3	19136429
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	SYNRG HBS1L PRCC NFRKB MCCC1 HSPA6 EMSY	4.16e-05	444	73	7	34795231
Pubmed	An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.	NOMO2 NOMO3 NOMO1	4.63e-05	33	73	3	30783098
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ANK3 MGST1 ERC1 PCLO UBR4 MACF1 MCCC1 MYO15A RYR1	4.81e-05	807	73	9	30575818
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CASP8AP2 DDX31 ANK3 NOMO2 PRCC UBR4 MACF1 AKAP11 HSPA6 SNX1 THOC5 NOMO1	5.85e-05	1487	73	12	33957083
Pubmed	Identification of six novel genes by experimental validation of GeneMachine predicted genes.	CEP350 CACNA1E	6.48e-05	6	73	2	11891061
Pubmed	Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction.	PCLO RYR1	6.48e-05	6	73	2	31804576
Pubmed	Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain.	CEP350 ANK3 THOC5	7.68e-05	39	73	3	22802532
Pubmed	Rebuilding essential active zone functions within a synapse.	CACNA1E ERC1	9.06e-05	7	73	2	35176221
Pubmed	Identification of genetic loci associated with Helicobacter pylori serologic status.	TLR1 HSPA6	9.06e-05	7	73	2	23652523
Pubmed	PDGF-A and PDGF-B induces cardiac fibrosis in transgenic mice.	PDGFRB PODXL	9.06e-05	7	73	2	27816607
Pubmed	USP7 Regulates Cytokinesis through FBXO38 and KIF20B.	NOMO2 DHX40 NFRKB HSPA6	1.07e-04	116	73	4	30804394
Pubmed	Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.	ADGRF4 ADGRG4	1.21e-04	8	73	2	12435584
Pubmed	UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy.	PDGFRB UBR4	1.21e-04	8	73	2	23431188
Pubmed	Glomerular mesangial cell recruitment and function require the co-receptor neuropilin-1.	PDGFRB PODXL	1.21e-04	8	73	2	28835419
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SCYL2 FEM1B HBS1L NOMO2 PODXL MACF1 ARFIP2 TMEM38B	1.32e-04	719	73	8	35337019
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	SEPTIN8 SYNRG ERC1 AKAP11	1.43e-04	125	73	4	29467281
Pubmed	Identification of a family of sorting nexin molecules and characterization of their association with receptors.	PDGFRB SNX1	1.55e-04	9	73	2	9819414
Pubmed	A CNS-specific hypomorphic Pdgfr-beta mutant model of diabetic retinopathy.	PDGFRB PODXL	1.55e-04	9	73	2	23633653
Pubmed	Human immunodeficiency virus type 1 Vpr links proteasomal degradation and checkpoint activation.	UBR4 UBR3	1.55e-04	9	73	2	17855541
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	ANK3 CACNA2D2 ERC1 MACF1	1.57e-04	128	73	4	30995482
Pubmed	The cargo-selective retromer complex is a recruiting hub for protein complexes that regulate endosomal tubule dynamics.	WASHC5 SNX1	1.93e-04	10	73	2	20923837
Pubmed	Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis.	PDGFRB PODXL	1.93e-04	10	73	2	25358792
Pubmed	Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.	CEP350 UBR4 MACF1	2.27e-04	56	73	3	9455484
Pubmed	The sphingosine-1-phosphate receptor S1PR1 restricts sprouting angiogenesis by regulating the interplay between VE-cadherin and VEGFR2.	PDGFRB PODXL	2.36e-04	11	73	2	22975327
Pubmed	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	ANK3 PCLO	2.36e-04	11	73	2	20351715
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	MGST1 UBR4 MACF1 MCCC1	2.39e-04	143	73	4	30397336
Pubmed	Functional proteomics mapping of a human signaling pathway.	SCYL2 ANK3 UBR4 MACF1 SKIL NOMO3 NOMO1	2.44e-04	591	73	7	15231748
Pubmed	New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.	TMEM38B RYR1	2.83e-04	12	73	2	19095005
Pubmed	Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability.	PDGFRB PODXL	2.83e-04	12	73	2	32044971
Pubmed	HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1.	UBR4 UBR3	2.83e-04	12	73	2	17360488
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CACNA1E ANK3 PCLO MACF1 AKAP11	3.19e-04	281	73	5	28706196
Pubmed	The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.	SERPING1 NOMO3 NOMO1	3.86e-04	67	73	3	22046132
Pubmed	O-linked N-acetylglucosamine proteomics of postsynaptic density preparations using lectin weak affinity chromatography and mass spectrometry.	PCLO EMSY	3.89e-04	14	73	2	16452088
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	ERC1 PCLO	3.89e-04	14	73	2	21228161
Pubmed	Angiopoietin-1 Is Required for Vortex Vein and Choriocapillaris Development in Mice.	PDGFRB PODXL	3.89e-04	14	73	2	36172864
Pubmed	Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning.	PDGFRB PODXL	4.48e-04	15	73	2	26138478
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1E CACNA2D2	4.48e-04	15	73	2	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1E CACNA2D2	4.48e-04	15	73	2	24453333
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	CACNA1E HBS1L WASHC5 UBR4 NFRKB DHX57	4.94e-04	475	73	6	31040226
Pubmed	Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis.	PDGFRB PODXL	5.12e-04	16	73	2	31761722
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 HBS1L TLR1 UBR3 MACF1 THOC5	6.01e-04	493	73	6	15368895
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC16 MUC4	6.51e-04	18	73	2	18834073
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	WASHC5 DHX57 AKAP11 ARFIP2 TMEM38B SNX1	6.74e-04	504	73	6	34432599
Pubmed	Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.	MGST1 IRX6 TMEM38B PCDH17	7.42e-04	193	73	4	22589738
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	SCYL2 SYNRG PODXL ARFIP2 SNX1	7.46e-04	339	73	5	37232246
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SCYL2 SYNRG PRCC ERC1 MACF1 MCCC1 SNX1 EMSY	7.56e-04	934	73	8	33916271
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SEPTIN8 PCLO UBR4	8.29e-04	87	73	3	12465718
Pubmed	Cullin-3/KCTD10 complex is essential for K27-polyubiquitination of EIF3D in human hepatocellular carcinoma HepG2 cells.	PCLO HSPA7 SNX1	9.14e-04	90	73	3	31280863
Pubmed	Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.	PDGFRB PODXL SERPING1	9.14e-04	90	73	3	28535371
Pubmed	The sequence and analysis of duplication-rich human chromosome 16.	NOMO2 NOMO3 NOMO1	9.14e-04	90	73	3	15616553
Pubmed	Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.	NOMO2 NOMO3 NOMO1	9.74e-04	92	73	3	10493829
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	PRCC ERC1 MACF1 MCCC1 EMSY	9.76e-04	360	73	5	33111431
Pubmed	SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination.	FBXO47 STAG3	9.77e-04	22	73	2	35489071
Pubmed	Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6.	UBR3 CCNB1IP1	9.77e-04	22	73	2	24981174
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ANK3 ERC1 UBR4 SERPING1 MACF1	9.88e-04	361	73	5	26167880
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	CASP8AP2 MGST1 PODXL ERC1 SHPRH STAG3 SNX1	1.03e-03	754	73	7	35906200
Pubmed	Ascending Vasa Recta Are Angiopoietin/Tie2-Dependent Lymphatic-Like Vessels.	PDGFRB PODXL	1.07e-03	23	73	2	29237738
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	CACNA2D2 PODXL MUC16 AKAP11 NOMO3 RYR1	1.08e-03	552	73	6	10737800
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	ZNF704 DHX40 SHPRH MUC4 SERPINA7	1.11e-03	371	73	5	15747579
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	WASHC5 PRCC DHX40 HSPA6 SNX1	1.21e-03	378	73	5	34315543
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SCYL2 ANK3 ERC1 MACF1 ARFIP2 SNX1	1.21e-03	565	73	6	25468996
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CEP350 ANK3 PODXL MUC16 MCCC1 ARFIP2 SNX1	1.23e-03	777	73	7	35844135
Pubmed	Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.	OR10A3 EMSY	1.26e-03	25	73	2	23042114
GeneFamily	Ubiquitin protein ligase E3 component n-recognins	UBR4 UBR3	1.69e-04	7	52	2	785
GeneFamily	DEAH-box helicases	DHX40 DHX57	9.49e-04	16	52	2	500
GeneFamily	Heat shock 70kDa proteins	HSPA6 HSPA7	1.07e-03	17	52	2	583
GeneFamily	CD molecules\|Mucins	MUC16 MUC4	1.65e-03	21	52	2	648
GeneFamily	Calcium voltage-gated channel subunits	CACNA1E CACNA2D2	2.52e-03	26	52	2	253
GeneFamily	Cytochrome P450 family 4	CYP4Z2P CYP4Z1	4.80e-03	36	52	2	1003
GeneFamily	Serpin peptidase inhibitors	SERPING1 SERPINA7	5.07e-03	37	52	2	739
GeneFamily	Cyclins\|F-boxes other	FBXO47 FBXO30	5.62e-03	39	52	2	560
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	IGSF10 PDGFRB LRRC4	1.11e-02	161	52	3	593
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	DDX31 AKAP11 RYR1	1.52e-02	181	52	3	694
Coexpression	ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN	RHPN2 PDGFRB NOMO2 SERPING1 ACTRT1 NOMO3 NOMO1	2.88e-06	222	73	7	M16955
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	IGSF10 NPY1R ANK3 CACNA2D2 ERC1 PCLO	7.05e-07	190	73	6	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	P15-Mesenchymal\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGST1 PDGFRB SERPING1 MACF1 TMEM38B	1.44e-05	188	73	5	f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	ANK3 MGST1 CACNA2D2 PCLO MCCC1	1.59e-05	192	73	5	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 NPY1R PDGFRB SERPING1 ADGRG4	1.72e-05	195	73	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Control-B_naive-9\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	HBS1L MGST1 RHPN2 WASHC5	5.00e-05	123	73	4	36d509eae874733f1a4f8189ad3000136ff6425e
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 MGST1 CYP4Z1 CACNA2D2	1.35e-04	159	73	4	e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCell	5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCLO FBXO47 ADGRG4 SERPINA7	1.45e-04	162	73	4	9f568836199a05f696294caac1ea3fa413984423
ToppCell	normal_Lung-Epithelial_cells-Undetermined\|normal_Lung / Location, Cell class and cell subclass	ANK3 MGST1 CACNA2D2 SERPING1	1.52e-04	164	73	4	fa2dae15b38cb8f9642dbf00549beec8ee19e9bb
ToppCell	343B-Lymphocytic-ILC\|343B / Donor, Lineage, Cell class and subclass (all cells)	ZBTB37 ZNF701 HSPA6 CCDC7	1.60e-04	166	73	4	a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TSGA10 MUC4 HSPA6 SNX1	1.63e-04	167	73	4	e242827999caad08b0894d88ab97bc1df41b7650
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	ZBTB37 RBM44 STAG3 CCDC7	1.67e-04	168	73	4	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RHPN2 PODXL ADGRF4 MUC4	1.71e-04	169	73	4	aec97583b23112060437b619cb429dc32f29285f
ToppCell	severe_COVID-19-Neutrophil\|severe_COVID-19 / disease group, cell group and cell class (v2)	CACNA1E SERPING1 LRRC4 HSPA6	1.83e-04	172	73	4	8f4bcb9b2bbf8b4333f673d8ad6bb88dfda4792a
ToppCell	Globus_pallidus-Endothelial-MURAL-M1(Rgs5Acta2)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZNF704 NPY1R PDGFRB SERPING1	1.87e-04	173	73	4	51328a60ffaf34fa0f7df6084d348b5efc9917f5
ToppCell	Globus_pallidus-Endothelial-MURAL\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	ZNF704 NPY1R PDGFRB SERPING1	1.87e-04	173	73	4	b77cd5dbda3a206922f20224f4e10a3bf712f7db
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYO15A SERPINA7 CCDC7	1.90e-04	68	73	3	6945089858778301a05ecc5895310d768768758c
ToppCell	Globus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Neurod2-Excitatory_Neuron.Slc17a7.Neurod2-Rorb_(Nucleus_of_the_lateral_olfactory_tract_(LOT))\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MYO15A SERPINA7 CCDC7	1.90e-04	68	73	3	ac9d0f473c878b96a422bbdd7088eb8125574dde
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CACNA1E NPY1R MGST1 PCDH17	1.91e-04	174	73	4	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MGST1 PCLO MUC16 MUC4	1.91e-04	174	73	4	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SEPTIN8 ANK3 MUC16 MUC4	1.91e-04	174	73	4	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 MUC16 MACF1 MUC4	2.13e-04	179	73	4	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASP8AP2 SYNRG MGST1 RHPN2	2.17e-04	180	73	4	baa5825e6ce23a98d9c21d024a4b0ab8ba353d0c
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	RHPN2 MUC16 LRRC4 MUC4	2.17e-04	180	73	4	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASP8AP2 SYNRG MGST1 RHPN2	2.17e-04	180	73	4	2d608b9394d28d19cfc85c6ac94003d5177c8a92
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Dendritic_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPY1R MGST1 SERPING1 FBXO30	2.17e-04	180	73	4	5b7d2336ed09d07f6b8dd91c1fa9c5ade633c104
ToppCell	facs-Lung-24m-Endothelial-arterial_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CASP8AP2 SYNRG MGST1 RHPN2	2.17e-04	180	73	4	0f9b27054358c4737eed06c8ea01987cccc3cb55
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGST1 SERPING1 MACF1 TMEM38B	2.22e-04	181	73	4	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	COPD-Epithelial-Basal\|World / Disease state, Lineage and Cell class	CYP4Z2P ANK3 CYP4Z1 MUC4	2.22e-04	181	73	4	6d8a886b4afe729f8a05b9c0f4ea9375de735da4
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGST1 SERPING1 MACF1 TMEM38B	2.27e-04	182	73	4	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGST1 SERPING1 MACF1 TMEM38B	2.27e-04	182	73	4	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGST1 SERPING1 MACF1 TMEM38B	2.36e-04	184	73	4	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CASP8AP2 PRCC UBR3 EMSY	2.36e-04	184	73	4	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF704 ANK3 MGST1 PCDH17	2.36e-04	184	73	4	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 MGST1 ERC1 MCCC1	2.41e-04	185	73	4	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGST1 SERPING1 MACF1 TMEM38B	2.41e-04	185	73	4	46460e74cc613df9043f5404e7342aa13cc34873
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MGST1 SERPING1 MACF1 TMEM38B	2.46e-04	186	73	4	88e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 MGST1 CACNA2D2 MCCC1	2.51e-04	187	73	4	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CACNA1E TLR1 SERPING1 HSPA6	2.57e-04	188	73	4	aa46073e2940dc1d2020b2e259bf0fc06cb990ee
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CACNA1E TLR1 SERPING1 HSPA6	2.57e-04	188	73	4	04814b78da936a51a497e23060d19ca0d619e250
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEPTIN8 NPY1R PDGFRB TMEM38B	2.62e-04	189	73	4	de51fbd6fdb24fc4549393cf41a020005444b2aa
ToppCell	hematopoetic_progenitors-CD34+_HSC\|World / Lineage and Cell class	IGSF10 SERPING1 CCNB1IP1 PCDH17	2.62e-04	189	73	4	51ff31c9cf5eff98ad01c0455dc4ae4908713575
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	ANK3 MGST1 MUC16 MUC4	2.67e-04	190	73	4	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 RHPN2 MUC16 MUC4	2.67e-04	190	73	4	2fdc024d3d673a0134b74b4c5a63afe924995730
ToppCell	hematopoetic_progenitors\|World / Lineage and Cell class	IGSF10 MGST1 SERPING1 CCNB1IP1	2.72e-04	191	73	4	bc77789297974587d51f9e4fae22cea5f499354d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANK3 MGST1 CACNA2D2 MCCC1	2.72e-04	191	73	4	a0332a4ef629510fb313ec119195c44a3f704a80
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ANK3 MGST1 CACNA2D2 PCLO	2.72e-04	191	73	4	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Epithelial-alveolar_epithelial_cell_type_2\|World / Lineage, Cell type, age group and donor	ANK3 MGST1 CACNA2D2 MCCC1	2.78e-04	192	73	4	58c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 MGST1 CYP4Z1 MCCC1	2.78e-04	192	73	4	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 UBR4 MACF1 PCDH17	2.78e-04	192	73	4	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2\|Adult / Lineage, Cell type, age group and donor	ANK3 MGST1 CACNA2D2 MCCC1	2.83e-04	193	73	4	738f4f0a9ddde2432b429ab46838e353b1790589
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 RHPN2 PCLO TSGA10	2.89e-04	194	73	4	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF10 MGST1 SERPING1 SKIL	2.95e-04	195	73	4	d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCell	AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ANK3 MGST1 CACNA2D2 MCCC1	2.95e-04	195	73	4	0792c1e959e933b10ae987d821ff43020dfdabad
ToppCell	343B\|World / Donor, Lineage, Cell class and subclass (all cells)	MGST1 CACNA2D2 MUC4 PCDH17	2.95e-04	195	73	4	2290911fde6efacfa38b985a2541322968bee42d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 PDGFRB SERPING1 MACF1	2.95e-04	195	73	4	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 PDGFRB SERPING1 MACF1	2.95e-04	195	73	4	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 MGST1 MUC16 MUC4	2.95e-04	195	73	4	e7230a849ea31e6eef9bc6f5468938499450582d
ToppCell	hematopoetic_progenitors-CD34+_MPP\|World / Lineage and Cell class	IGSF10 MGST1 SERPING1 CCNB1IP1	2.95e-04	195	73	4	851064ca1ab727b4972ad4b72234ee130998a799
ToppCell	COPD-Multiplet-Multiplet\|COPD / Disease state, Lineage and Cell class	CYP4Z2P ANK3 MACF1 MUC4	3.01e-04	196	73	4	af4cdc61830685a888a1209826c23bcf54a43084
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 PDGFRB SERPING1 MACF1	3.01e-04	196	73	4	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 RHPN2 PCLO TSGA10	3.01e-04	196	73	4	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	(05)_Secretory\|World / shred by cell type by condition	MGST1 PODXL MUC16 MUC4	3.01e-04	196	73	4	8032c25b51ef96aeba28cc52686a2bd45213453d
ToppCell	COPD-Multiplet\|COPD / Disease state, Lineage and Cell class	CYP4Z2P ANK3 MACF1 MUC4	3.01e-04	196	73	4	6d02d494196e3f857d53eea46d9419690d43beca
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CYP4Z2P ANK3 RHPN2 MUC4	3.01e-04	196	73	4	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IGSF10 PDGFRB SERPING1 MACF1	3.06e-04	197	73	4	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ANK3 MGST1 PCLO PCDH17	3.06e-04	197	73	4	4ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCell	BL-critical-LOC-Epithelial-Secretory_LYPD2\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MGST1 PCLO MUC16 MUC4	3.12e-04	198	73	4	484d16aaa601a1e11b871b0475dd01a2de1a29ce
ToppCell	moderate-Epithelial-Secretory\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MGST1 PODXL MUC16 MUC4	3.12e-04	198	73	4	7d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCell	ASK428-Epithelial-Type_2\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	ANK3 MGST1 CACNA2D2 MCCC1	3.12e-04	198	73	4	ec0d1801363adb70c6a26655b79d12b438c7417d
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 MGST1 CACNA2D2 MCCC1	3.12e-04	198	73	4	2e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCell	NS-critical-LOC-Epithelial-Secretory_LYPD2\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MGST1 PODXL MUC16 MUC4	3.12e-04	198	73	4	4a481e1edb80b950c823ed926842cd5132cfb27f
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	CACNA1E NPY1R ANK3 PCLO	3.18e-04	199	73	4	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	Bronchial-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 MGST1 CACNA2D2 MCCC1	3.18e-04	199	73	4	5f7da3eab58ace6cddb3179a415cd839d5767958
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 MGST1 CACNA2D2 MCCC1	3.18e-04	199	73	4	8587bd98de7767a575088afbea07a1feb4516b9b
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 MGST1 CACNA2D2 MCCC1	3.18e-04	199	73	4	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	CACNA1E NPY1R ANK3 PCLO	3.18e-04	199	73	4	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	IGSF10 PDGFRB SERPING1 MACF1	3.18e-04	199	73	4	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 MGST1 CACNA2D2 MCCC1	3.18e-04	199	73	4	2dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	IGSF10 PDGFRB SERPING1 MACF1	3.18e-04	199	73	4	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	IGSF10 PDGFRB SERPING1 MACF1	3.18e-04	199	73	4	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	Bronchial_Biopsy-Epithelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	ANK3 MGST1 MUC16 MUC4	3.18e-04	199	73	4	ef5d8917c8d011184830a0b8197afc6266707b37
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IGSF10 PDGFRB SERPING1 MACF1	3.24e-04	200	73	4	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	control-Epithelial\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANK3 MGST1 MUC16 MUC4	3.24e-04	200	73	4	f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IGSF10 PDGFRB SERPING1 MACF1	3.24e-04	200	73	4	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANK3 TSGA10 MUC16 MUC4	3.24e-04	200	73	4	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANK3 MGST1 CACNA2D2 MUC4	3.24e-04	200	73	4	21d9cf3cd3696ad6b745c7c036798f04b6ce5160
ToppCell	NS-control-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANK3 MGST1 MUC16 MUC4	3.24e-04	200	73	4	d014959891893b6d3854a471fba1dc50c6625a0a
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IGSF10 PDGFRB SERPING1 MACF1	3.24e-04	200	73	4	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	367C-Fibroblasts-Fibroblast-E-\|367C / Donor, Lineage, Cell class and subclass (all cells)	IGSF10 MGST1 PDGFRB SERPING1	3.24e-04	200	73	4	57b9d6aa2265ab178a5886f36ecc66115bd382a8
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	CACNA1E NPY1R ANK3 PCLO	3.24e-04	200	73	4	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	cellseq-Epithelial\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ANK3 MGST1 CACNA2D2 MUC4	3.24e-04	200	73	4	e4204c4b864346f47d76b0f0faae96f04fed5082
ToppCell	distal-Epithelial\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANK3 MGST1 CACNA2D2 MUC4	3.24e-04	200	73	4	0a97080f694738bb882787cee21b91a4d5757b7a
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 RHPN2 PCLO MUC16	3.24e-04	200	73	4	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	IGSF10 PDGFRB SERPING1 MACF1	3.24e-04	200	73	4	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	Biopsy_Other_PF-Epithelial\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ANK3 MGST1 CACNA2D2 MUC4	3.24e-04	200	73	4	1ef4d5ae698fa721e0f510bf0d918bd8d3b00591
ToppCell	Lung_Parenchyma-Severe-Epithelial\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ANK3 MGST1 CACNA2D2 MUC4	3.24e-04	200	73	4	33658d5d09e2eaff60f4dd88837d4252328eab63
ToppCell	Parenchyma_COVID-19-Epithelial-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ANK3 MGST1 CACNA2D2 MUC4	3.24e-04	200	73	4	d5426cd318a8f90c0bd8f9804351ab230fafc995
ToppCell	ASK428-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	ANK3 MGST1 CACNA2D2 MCCC1	3.24e-04	200	73	4	8919d7371b9d9a061d52664532980c6ea20d0473
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_adventitial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	NPY1R MGST1 PDGFRB SERPING1	3.24e-04	200	73	4	9dd2eb70c1cc146935f5aff27373dfc65cb8c098
ToppCell	Parenchymal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANK3 MGST1 CACNA2D2 MUC4	3.24e-04	200	73	4	4e5b6cb014d9bcb58e13c7511c86c43e27c496e4
Disease	10-undecenoate 11:1n1 measurement	CYP4Z2P CYP4Z1	1.16e-04	7	70	2	EFO_0021099
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	HSPA6 HSPA7	7.37e-04	17	70	2	EFO_0021969
Disease	carnitine measurement	ANK3 MCCC1 SERPINA7	7.94e-04	76	70	3	EFO_0010469
Disease	low affinity immunoglobulin gamma Fc region receptor II-b measurement	HSPA6 HSPA7	1.61e-03	25	70	2	EFO_0021970

Protein segments in the cluster

Peptide	Gene	Start	Entry
ISILKIFITMMSKSV	CYP4Z2P	146	Q8N1L4
NLVVSLMSSMKSIIS	CACNA1E	591	Q15878
SSVKVMLSKTMDKEN	CCDC7	216	Q96M83
TLKLMKTSVCEMLDT	CACNA2D2	306	Q9NY47
TKTTKMVEAMATEIF	ADGRG4	351	Q8IZF6
SFSILMSSKSMTDKV	ADGRF4	386	Q8IZF3
MSSKSMTDKVLDYIT	ADGRF4	391	Q8IZF3
ETLESMTSLEVTKMV	AKAP11	886	Q9UKA4
NTLVTKTMEDTLMTV	ARFIP2	211	P53365
MEMKVALSTTVSETT	CASP8AP2	746	Q9UKL3
TKSKAMPMSRVSTVT	ARMCX5	106	Q6P1M9
MPMSRVSTVTKSEVK	ARMCX5	111	Q6P1M9
QTVIEMKDSKISSME	ERC1	381	Q8IUD2
VSTSSNTEITMMNKK	RBM44	491	Q6ZP01
TITTDKMMDVTVTIK	NOMO3	671	P69849
KMMDVTVTIKSSIDS	NOMO3	676	P69849
DMSVREALKMKTTST	PCDH17	911	O14917
MLAIITKMTLTQVST	IRX6	181	P78412
MDVGMTKFETTTKVI	HBS1L	326	Q9Y450
SSMVVIDVKMLSGFT	OVOS1	1106	Q6IE37
IMTKSAEMTVTTQTT	MUC16	5556	Q8WXI7
SVTNTLMMTSKTITM	MUC4	126	Q99102
LMMTSKTITMTTSTD	MUC4	131	Q99102
METSSEMQEKKVVSL	PODXL	516	O00592
TITTDKMMDVTVTIK	NOMO2	671	Q5JPE7
KMMDVTVTIKSSIDS	NOMO2	676	Q5JPE7
MLVVLSTEKTMISFV	OR10A3	81	P58181
MMATLAKSQVTTVKL	NFRKB	976	Q6P4R8
ARTVLKSTSKLMTQM	MYO15A	76	Q9UKN7
TIILSKMMLMSTATA	MGST1	21	P10620
TTGVSEILLKTQMKM	FEM1B	581	Q9UK73
MLTKMSSTLSKVFSQ	FSIP2	6876	Q5CZC0
TMDESTSSVMTKIIE	PCLO	2911	Q9Y6V0
TITTDKMMDVTVTIK	NOMO1	671	Q15155
KMMDVTVTIKSSIDS	NOMO1	676	Q15155
QTSKSTMEKMEGSTI	MACF1	56	O94854
TTDKMQTSLDEVMKT	LRRC4	511	Q9HBW1
SLTTILDMVKVMTFA	PTPDC1	166	A2A3K4
LISTINTVLKMSSMT	DDX31	241	Q9H8H2
ISSMVLSKMKETAEA	HSPA7	121	P48741
AMSTMHTDVSKTSLK	NPY1R	351	P25929
TMIKDVNVKMLSSTT	IGSF10	926	Q6WRI0
SKSVIKTMSIMDFEK	DHX57	811	Q6P158
SEMKTLKSQMGTLVE	CCDC13	361	Q8IYE1
SSETSSIMQKLKKMR	CEP350	1836	Q5VT06
ETMTTTTVTEKHKMN	ANK3	821	Q12955
IKVTTSQDMLSIMEK	SERPING1	401	P05155
AIRDMGIKSTSKSIM	MCCC1	156	Q96RQ3
VKDISMLSMVSKTVS	FBXO47	61	Q5MNV8
SEKTAVSDILKMSLM	EMSY	1141	Q7Z589
ISSMVLSKMKETAEA	HSPA6	121	P17066
LKVATMMSKATDKVS	FBXO30	136	Q8TB52
VVVMSATMELAKLSA	DHX40	206	Q8IX18
MSFDLSKVRVVTVTM	RYR1	1461	P21817
IICKMASMLSKSTVE	PPP4R1L	146	Q9P1A2
QATMKVAVKMLKSTA	PDGFRB	626	P09619
ISGTMTSEKTEMIVF	GARIN3	586	Q8TC56
MTKSLTEEKTMKSFS	PRCC	426	Q92733
MLSSSKSMKELTEEQ	SKIL	561	P12757
VATSQSKMKSSEEMI	SYNRG	1041	Q9UMZ2
KSTMTMEELLTSLQK	SHPRH	996	Q149N8
MESMLNKLKSTVTKV	SCYL2	1	Q6P3W7
IEMKVVSLLDSTSSM	RHPN2	586	Q8IUC4
ELSKIAEMTTQMKSL	TLR1	386	Q15399
SKMVSSSIMKCDTDI	ACTRT1	276	Q8TDG2
LTSMKGEVTSMKKVL	CCNB1IP1	136	Q9NPC3
ISILKIFITMMSESV	CYP4Z1	146	Q86W10
SIFTEGILMMKTTLV	WASHC5	681	Q12768
MSLNEMSTVSISVIK	ZBTB37	61	Q5TC79
ATDAVSKMTIKMNES	SNX1	291	Q13596
TLAAMKLMTSLVKVA	STAG3	236	Q9UJ98
QMESVEAAMSSKTLK	SERPINA7	276	P05543
IVATKITMMTTQTST	TMEM38B	216	Q9NVV0
SLSSSKVMMTKASVE	SEPTIN8	441	Q92599
DMDKVTAAMVLTSLS	ZNF704	81	Q6ZNC4
TLMKETISTVEKEMK	TSGA10	166	Q9BZW7
SKEMESVMKDIKNTT	UBR3	1416	Q6ZT12
EALMTKTKKLMSSTE	ZNF701	176	Q9NV72
NIMTVKAKVTTAMEL	THOC5	371	Q13769
TEIITFTAMMKSAKL	UBR4	146	Q5T4S7