Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionkinase activity

TNIK SLK SPEG PAK5 MINK1 PAK4 DGKB DGKE GCK NME9 GRK1 BLK STK3 STK4 GUCY2C SPHK1 SHPK PAK1 PAK2 PRKD1 EPHA1 EPHA4

1.06e-0976412122GO:0016301
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

TNIK SLK SPEG PAK5 MINK1 PAK4 DGKB DGKE GCK GRK1 BLK STK3 STK4 GUCY2C SPHK1 SHPK PAK1 PAK2 PRKD1 EPHA1 EPHA4

1.62e-0970912121GO:0016773
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

TNIK SLK SPEG PAK5 MINK1 PAK4 DGKB DGKE GCK NME9 GRK1 BLK STK3 STK4 GUCY2C SPHK1 SHPK PAK1 PAK2 PRKD1 EPHA1 EPHA4

4.36e-0893812122GO:0016772
GeneOntologyMolecularFunctionprotein kinase activity

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 BLK STK3 STK4 GUCY2C PAK1 PAK2 PRKD1 EPHA1 EPHA4

6.98e-0760012116GO:0004672
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA4 GRIK4 GRIN2A GRIN2B

2.87e-06171214GO:0004970
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA4 GRIK4 GRIN2A GRIN2B

1.24e-05241214GO:0099507
GeneOntologyMolecularFunctionprotein serine kinase activity

TNIK SLK SPEG PAK5 MINK1 PAK4 STK3 STK4 PAK1 PAK2 PRKD1

1.32e-0536312111GO:0106310
GeneOntologyMolecularFunctionprotein serine/threonine kinase activity

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 STK3 STK4 PAK1 PAK2 PRKD1

1.73e-0544612112GO:0004674
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA4 GRIK4 GRIN2A GRIN2B

2.02e-05271214GO:0008066
GeneOntologyMolecularFunctionamyloid-beta binding

APBB1 APBB2 GRIA4 GRIN2A GRIN2B EPHA4

3.66e-051021216GO:0001540
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD3 CHD4 RAD54L2 ERCC6L2

7.26e-05371214GO:0140658
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

GRIA4 GRIK4 GRIN2A GRIN2B CLCA1 KCNN1 TRPM8

1.76e-041931217GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

GRIA4 GRIK4 GRIN2A GRIN2B CLCA1 KCNN1 TRPM8

2.00e-041971217GO:0022834
GeneOntologyMolecularFunctionCDP phosphatase activity

ENTPD6 ENTPD5

2.17e-0441212GO:0036384
GeneOntologyMolecularFunctionIDP phosphatase activity

ENTPD6 ENTPD5

3.60e-0451212GO:1990003
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIA4 GRIK4 GRIN2A GRIN2B

3.95e-04571214GO:1904315
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

GRIA4 GRIK4 GRIN2A GRIN2B SLC38A7

4.48e-041051215GO:0015171
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIA4 GRIK4 GRIN2A GRIN2B

4.81e-04601214GO:0099529
GeneOntologyMolecularFunctionkinase regulator activity

ITSN1 STK3 STK4 SH3GLB1 RPTOR CCNA1 PAK2 PRKD1

5.47e-043051218GO:0019207
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIA4 GRIK4 GRIN2A GRIN2B

6.53e-04651214GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIA4 GRIK4 GRIN2A GRIN2B

6.53e-04651214GO:0022824
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIN2A GRIN2B

7.50e-0471212GO:0005234
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIN2A GRIN2B TRPM8

8.62e-04311213GO:0099604
GeneOntologyMolecularFunctiongated channel activity

GRIA4 GRIK4 GRIN2A GRIN2B CLCA1 CLCN4 KCNN1 TRPM8

9.86e-043341218GO:0022836
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN2A GRIN2B

9.96e-0481212GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN2A GRIN2B

9.96e-0481212GO:0004972
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIA4 GRIK4 GRIN2A GRIN2B

1.12e-03751214GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIA4 GRIK4 GRIN2A GRIN2B

1.23e-03771214GO:0005230
GeneOntologyMolecularFunctionphosphatidylinositol 3-kinase activator activity

SH3GLB1 PRKD1

1.28e-0391212GO:0141038
GeneOntologyMolecularFunctionUDP phosphatase activity

ENTPD6 ENTPD5

1.28e-0391212GO:0045134
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

GRIK4 GRIN2A GRIN2B KCNN1 TRPM8

1.64e-031401215GO:0099094
GeneOntologyMolecularFunctionATP-dependent diacylglycerol kinase activity

DGKB DGKE

1.93e-03111212GO:0004143
GeneOntologyMolecularFunctionlipid kinase activity

DGKB DGKE SPHK1

1.96e-03411213GO:0001727
GeneOntologyMolecularFunctionGDP phosphatase activity

ENTPD6 ENTPD5

2.31e-03121212GO:0004382
GeneOntologyMolecularFunctionamide binding

APBB1 APBB2 GRIA4 GRIN2A GRIN2B MCCC1 EPHA4

2.32e-032991217GO:0033218
GeneOntologyMolecularFunctionactin filament binding

VIL1 SPTBN2 CORO1B CORO1A FMNL1 CNN3

2.62e-032271216GO:0051015
GeneOntologyMolecularFunctionkinase activator activity

ITSN1 STK3 STK4 RPTOR PAK2

2.85e-031591215GO:0019209
GeneOntologyMolecularFunctionglutamate binding

GRIN2A GRIN2B

3.16e-03141212GO:0016595
GeneOntologyMolecularFunctionneurotransmitter receptor activity

GRIA4 GRIK4 GRIN2A GRIN2B

3.22e-031001214GO:0030594
GeneOntologyMolecularFunctionpeptide binding

TNPO1 APBB1 APBB2 GRIA4 GRIN2A GRIN2B EPHA4

3.27e-033181217GO:0042277
GeneOntologyMolecularFunctiontransmembrane-ephrin receptor activity

EPHA1 EPHA4

3.63e-03151212GO:0005005
GeneOntologyBiologicalProcessprotein autophosphorylation

TNIK SLK MINK1 GRK1 STK4 PAK1 PAK2 PRKD1 EPHA1 EPHA4

8.98e-0722812010GO:0046777
GeneOntologyBiologicalProcessdendrite development

TNIK ITSN1 MINK1 PAK4 RAPGEF4 DPYSL5 FBXW8 SH3GLB1 PAK1 PAK2 EPHA4

4.23e-0633512011GO:0016358
GeneOntologyBiologicalProcessneuron projection development

TNIK FAT4 TOX ITSN1 MINK1 PAK4 RAPGEF4 DPYSL5 APBB1 APBB2 MAPK8IP3 FBXW8 SH3GLB1 HMCN2 SPHK1 PAK1 PAK2 PRKD1 VPS13B EPHA4 CREB3L2

1.53e-05128512021GO:0031175
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIA4 GRIK4 GRIN2A GRIN2B

1.72e-05271204GO:0035235
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

TNIK VIL1 TOX APBB1 CORO1B FBXW8 SH3GLB1 SPHK1 PAK1 PRKD1 EPHA4 CREB3L2

3.16e-0549412012GO:0031346
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

TNIK VIL1 TOX RAPGEF4 DPYSL5 APBB1 CORO1B GRIN2B FBXW8 SH3GLB1 SPHK1 PAK1 PAK2 PRKD1 EPHA4 CREB3L2

3.20e-0584612016GO:0120035
GeneOntologyBiologicalProcessneuron development

TNIK FAT4 TOX ITSN1 MINK1 PAK4 RAPGEF4 DPYSL5 APBB1 APBB2 MAPK8IP3 GRK1 FBXW8 SH3GLB1 HMCN2 SPHK1 PAK1 PAK2 PRKD1 VPS13B EPHA4 CREB3L2

3.35e-05146312022GO:0048666
GeneOntologyBiologicalProcessregulation of cell projection organization

TNIK VIL1 TOX RAPGEF4 DPYSL5 APBB1 CORO1B GRIN2B FBXW8 SH3GLB1 SPHK1 PAK1 PAK2 PRKD1 EPHA4 CREB3L2

4.06e-0586312016GO:0031344
GeneOntologyBiologicalProcessphosphatidic acid biosynthetic process

AGPAT4 DGKB DGKE SH3GLB1

5.56e-05361204GO:0006654
GeneOntologyBiologicalProcessregulation of neuron projection development

TNIK TOX RAPGEF4 DPYSL5 APBB1 FBXW8 SH3GLB1 SPHK1 PAK1 PAK2 PRKD1 EPHA4 CREB3L2

5.83e-0561212013GO:0010975
GeneOntologyBiologicalProcesscell morphogenesis

TNIK VIL1 MINK1 DPYSL5 APBB1 APBB2 CORO1B SIPA1 MAPK8IP3 GRK1 STK4 CORO1A FBXW8 SH3GLB1 HMCN2 PAK1 PAK2 FMNL1 EPHA4

5.88e-05119412019GO:0000902
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIA4 GRIK4 GRIN2A GRIN2B

8.47e-05401204GO:1990806
GeneOntologyBiologicalProcessphosphatidic acid metabolic process

AGPAT4 DGKB DGKE SH3GLB1

9.34e-05411204GO:0046473
GeneOntologyBiologicalProcesspositive regulation of establishment of protein localization

SEC16B CCT3 RAPGEF4 APBB1 GCK GRIN2A BLK SH3GLB1 PAK1 PRKD1

1.25e-0440312010GO:1904951
GeneOntologyBiologicalProcessregulation of dendrite development

TNIK RAPGEF4 DPYSL5 FBXW8 SH3GLB1 EPHA4

2.47e-041501206GO:0050773
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

TNIK VIL1 MINK1 DPYSL5 APBB1 APBB2 CORO1B MAPK8IP3 FBXW8 SH3GLB1 HMCN2 PAK1 PAK2 EPHA4

2.94e-0481912014GO:0120039
GeneOntologyBiologicalProcessnegative regulation of apoptotic process

MAGEA4 HYOU1 ITSN1 PAK5 PAK4 APBB2 GRIA4 MAPK8IP3 GRK1 FAIM CORO1A SH3GLB1 ARL6IP1 SPHK1 PAK2 CABIN1 EPHA4

3.00e-04113312017GO:0043066
GeneOntologyBiologicalProcesscell projection morphogenesis

TNIK VIL1 MINK1 DPYSL5 APBB1 APBB2 CORO1B MAPK8IP3 FBXW8 SH3GLB1 HMCN2 PAK1 PAK2 EPHA4

3.20e-0482612014GO:0048858
GeneOntologyBiologicalProcessregulation of cell differentiation involved in embryonic placenta development

STK3 STK4

3.32e-0451202GO:0060800
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

MINK1 SPTBN2 RAPGEF4 DGKB GRIA4 DGKE GRIK4 GRIN2A GRIN2B SLC12A2 SPHK1 PAK1 KCNN1 KMT2A EPHA4

3.32e-0493112015GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

MINK1 SPTBN2 RAPGEF4 DGKB GRIA4 DGKE GRIK4 GRIN2A GRIN2B SLC12A2 SPHK1 PAK1 KCNN1 KMT2A EPHA4

3.32e-0493112015GO:0007268
GeneOntologyBiologicalProcessregulation of dendrite morphogenesis

TNIK DPYSL5 FBXW8 SH3GLB1 EPHA4

3.41e-041031205GO:0048814
GeneOntologyBiologicalProcesstrans-synaptic signaling

MINK1 SPTBN2 RAPGEF4 DGKB GRIA4 DGKE GRIK4 GRIN2A GRIN2B SLC12A2 SPHK1 PAK1 KCNN1 KMT2A EPHA4

3.64e-0493912015GO:0099537
GeneOntologyBiologicalProcessregulation of actin filament organization

VIL1 SPTBN2 CORO1B CORO1A PAK1 KANK4 PAK2 EPHA1

3.75e-043001208GO:0110053
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

GRIA4 GRIK4 GRIN2A GRIN2B

3.87e-04591204GO:0007215
GeneOntologyBiologicalProcessregulation of cell morphogenesis

TNIK VIL1 CORO1B CORO1A FBXW8 SH3GLB1 FMNL1 EPHA4

3.92e-043021208GO:0022604
GeneOntologyBiologicalProcessregulation of actin cytoskeleton organization

VIL1 SPTBN2 CORO1B CORO1A PAK1 KANK4 PAK2 PRKD1 EPHA1

4.16e-043841209GO:0032956
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

TNIK MINK1 DPYSL5 APBB1 APBB2 MAPK8IP3 GRK1 FBXW8 SH3GLB1 HMCN2 PAK1 PAK2 EPHA4

4.18e-0474812013GO:0048667
GeneOntologyBiologicalProcessnegative regulation of programmed cell death

MAGEA4 HYOU1 ITSN1 PAK5 PAK4 APBB2 GRIA4 MAPK8IP3 GRK1 FAIM CORO1A SH3GLB1 ARL6IP1 SPHK1 PAK2 CABIN1 EPHA4

4.38e-04117112017GO:0043069
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

RAPGEF4 DGKB GRIA4 DGKE GRIK4 GRIN2A GRIN2B SLC12A2 SPHK1 PAK1 KMT2A EPHA4

4.90e-0466312012GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

RAPGEF4 DGKB GRIA4 DGKE GRIK4 GRIN2A GRIN2B SLC12A2 SPHK1 PAK1 KMT2A EPHA4

4.97e-0466412012GO:0099177
GeneOntologyBiologicalProcesssynaptic signaling

MINK1 SPTBN2 RAPGEF4 DGKB GRIA4 DGKE GRIK4 GRIN2A GRIN2B SLC12A2 SPHK1 PAK1 KCNN1 KMT2A EPHA4

5.44e-0497612015GO:0099536
GeneOntologyBiologicalProcessprotein stabilization

CCT3 APBB1 APBB2 MAPK8IP3 STK3 STK4 EPHA4

5.56e-042431207GO:0050821
GeneOntologyBiologicalProcessmicrovillus assembly

TNIK VIL1 MINK1

5.66e-04281203GO:0030033
GeneOntologyBiologicalProcessregulation of establishment of protein localization

SEC16B CCT3 RAPGEF4 APBB1 GCK GRIN2A BLK SH3GLB1 SLC12A2 RPTOR PAK1 PRKD1

5.67e-0467412012GO:0070201
GeneOntologyBiologicalProcessregulation of cytoskeleton organization

VIL1 SPTBN2 FSD1 CORO1B SPAG5 CORO1A PAK1 KANK4 PAK2 PRKD1 EPHA1

5.69e-0457912011GO:0051493
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

TNIK VIL1 PAK4 DPYSL5 CORO1B CORO1A FBXW8 SH3GLB1 SLC12A2 SPHK1 PAK1 PAK2 PRKD1 FMNL1 EPHA1 EPHA4

5.81e-04109012016GO:0022603
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

ITSN1 RAPGEF4 APBB1 GCK GRIN2B BLK SLC12A2 SPHK1 PRKD1

5.99e-044041209GO:1903532
GeneOntologyBiologicalProcesspositive regulation of dendrite morphogenesis

TNIK FBXW8 SH3GLB1 EPHA4

6.29e-04671204GO:0050775
GeneOntologyBiologicalProcesssynapse organization

ITSN1 SPTBN2 RAPGEF4 APBB1 APBB2 DGKB CHD4 GRIN2A GRIN2B HMCN2 PAK1 EPHA4

6.54e-0468512012GO:0050808
GeneOntologyBiologicalProcesspositive regulation of protein localization

VIL1 SEC16B CCT3 RAPGEF4 APBB1 GCK GRIN2A BLK SH3GLB1 PAK1 PRKD1

6.74e-0459112011GO:1903829
GeneOntologyBiologicalProcesspositive regulation of lamellipodium morphogenesis

VIL1 CORO1B

6.92e-0471202GO:2000394
GeneOntologyBiologicalProcesspositive regulation of cell morphogenesis

TNIK FBXW8 SH3GLB1 EPHA4

7.04e-04691204GO:0010770
GeneOntologyBiologicalProcessregulation of actomyosin structure organization

PAK1 KANK4 PAK2 PRKD1 EPHA1

7.39e-041221205GO:0110020
GeneOntologyBiologicalProcessregulation of actin filament bundle assembly

VIL1 PAK1 KANK4 PAK2 EPHA1

7.67e-041231205GO:0032231
GeneOntologyBiologicalProcessactin cytoskeleton organization

TNIK VIL1 MINK1 SPTBN2 CORO1B CORO1A PAK1 KANK4 PAK2 PRKD1 FMNL1 CNN3 EPHA1

8.09e-0480312013GO:0030036
GeneOntologyBiologicalProcessembryonic hemopoiesis

STK3 STK4 KMT2A

8.42e-04321203GO:0035162
GeneOntologyBiologicalProcessglucose 6-phosphate metabolic process

GCK SHPK RPTOR

8.42e-04321203GO:0051156
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

GRIA4 GRIK4 GRIN2B

8.42e-04321203GO:0099505
GeneOntologyBiologicalProcessactin filament bundle assembly

VIL1 CORO1B PAK1 KANK4 PAK2 EPHA1

8.89e-041911206GO:0051017
GeneOntologyBiologicalProcessmaintenance of lens transparency

APBB2 VPS13B

9.19e-0481202GO:0036438
GeneOntologyBiologicalProcessregulation of MAPK cascade

TNIK ZNF274 PAK5 MINK1 PAK4 GRIN2B MAPK8IP3 STK3 STK4 SPHK1 PAK1 PAK2 EPHA4

9.27e-0481512013GO:0043408
GeneOntologyBiologicalProcessnegative regulation of cytoskeleton organization

VIL1 SPTBN2 CORO1B CORO1A KANK4 PAK2

9.63e-041941206GO:0051494
GeneOntologyBiologicalProcessactin filament bundle organization

VIL1 CORO1B PAK1 KANK4 PAK2 EPHA1

9.89e-041951206GO:0061572
GeneOntologyBiologicalProcessmicrovillus organization

TNIK VIL1 MINK1

1.01e-03341203GO:0032528
GeneOntologyBiologicalProcesspositive regulation of amino acid transport

GRIN2B SLC12A2 ARL6IP1

1.01e-03341203GO:0051957
GeneOntologyBiologicalProcesspositive regulation of secretion

ITSN1 RAPGEF4 APBB1 GCK GRIN2B BLK SLC12A2 SPHK1 PRKD1

1.01e-034351209GO:0051047
GeneOntologyBiologicalProcessnegative regulation of supramolecular fiber organization

VIL1 SPTBN2 CORO1B CORO1A KANK4 PAK2

1.04e-031971206GO:1902904
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

GRIA4 GRIK4 GRIN2A GRIN2B PAK1

1.05e-031321205GO:0035249
GeneOntologyBiologicalProcessregulation of actin filament-based process

VIL1 SPTBN2 CORO1B CORO1A PAK1 KANK4 PAK2 PRKD1 EPHA1

1.06e-034381209GO:0032970
GeneOntologyBiologicalProcessregulation of supramolecular fiber organization

VIL1 SPTBN2 CORO1B CORO1A PAK1 KANK4 PAK2 PRKD1 EPHA1

1.06e-034381209GO:1902903
GeneOntologyBiologicalProcesspositive regulation of cell motility

VIL1 ZNF609 RAPGEF4 MAPK8IP3 STK4 CORO1A DUOX1 SPHK1 PAK1 PRKD1 EPHA1 EPHA4

1.07e-0372512012GO:2000147
GeneOntologyBiologicalProcessdendrite morphogenesis

TNIK MINK1 DPYSL5 FBXW8 SH3GLB1 EPHA4

1.07e-031981206GO:0048813
GeneOntologyCellularComponentglutamatergic synapse

TNIK ITSN1 SPTBN2 RAPGEF4 DPYSL5 APBB1 DGKB GRIA4 DGKE CHD4 GRIK4 GRIN2A CORO1B GRIN2B CORO1A PAK1 PAK2 CNN3 EPHA4

2.33e-0781712119GO:0098978
GeneOntologyCellularComponentcell body

CCT3 ITSN1 SPTBN2 RAPGEF4 DPYSL5 APBB1 IREB2 GRIA4 GRIK4 GRIN2B MAPK8IP3 SH3GLB1 HMCN2 SLC12A2 RPTOR KCNN1 SLC38A7 CNN3 EPHA4

1.61e-0692912119GO:0044297
GeneOntologyCellularComponentneuronal cell body

ITSN1 SPTBN2 RAPGEF4 DPYSL5 APBB1 IREB2 GRIA4 GRIK4 GRIN2B SH3GLB1 HMCN2 SLC12A2 RPTOR KCNN1 SLC38A7 CNN3 EPHA4

6.41e-0683512117GO:0043025
GeneOntologyCellularComponentsomatodendritic compartment

ITSN1 MINK1 SPTBN2 RAPGEF4 DPYSL5 APBB1 IREB2 GRIA4 GRIK4 GRIN2A GRIN2B MAPK8IP3 SH3GLB1 HMCN2 SLC12A2 RPTOR PAK1 KCNN1 SLC38A7 CNN3 EPHA4

7.17e-06122812121GO:0036477
GeneOntologyCellularComponentaxon

ITSN1 MINK1 RAPGEF4 APBB1 APBB2 IREB2 GRIA4 GRIK4 GRIN2A GRIN2B MAPK8IP3 CORO1A HMCN2 SPHK1 PAK1 SLC38A7 EPHA4

1.49e-0589112117GO:0030424
GeneOntologyCellularComponentasymmetric synapse

TNIK MINK1 RAPGEF4 DGKB GRIA4 CHD4 GRIK4 GRIN2A GRIN2B PAK1 PAK2 EPHA4

2.14e-0547712112GO:0032279
GeneOntologyCellularComponentdistal axon

ITSN1 RAPGEF4 APBB1 APBB2 GRIA4 GRIK4 GRIN2A GRIN2B MAPK8IP3 PAK1 EPHA4

4.58e-0543512111GO:0150034
GeneOntologyCellularComponentneuron to neuron synapse

TNIK MINK1 RAPGEF4 DGKB GRIA4 CHD4 GRIK4 GRIN2A GRIN2B PAK1 PAK2 EPHA4

5.24e-0552312112GO:0098984
GeneOntologyCellularComponentpostsynaptic density

TNIK MINK1 RAPGEF4 DGKB GRIA4 GRIK4 GRIN2A GRIN2B PAK1 PAK2 EPHA4

6.33e-0545112111GO:0014069
GeneOntologyCellularComponentdendritic spine

ITSN1 RAPGEF4 APBB1 GRIA4 GRIN2A GRIN2B CNN3 EPHA4

8.40e-052421218GO:0043197
GeneOntologyCellularComponentneuron spine

ITSN1 RAPGEF4 APBB1 GRIA4 GRIN2A GRIN2B CNN3 EPHA4

9.68e-052471218GO:0044309
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIA4 GRIK4 GRIN2A GRIN2B

1.32e-04451214GO:0008328
GeneOntologyCellularComponentcell leading edge

VIL1 SLK ITSN1 APBB1 APBB2 GRIN2A CORO1B MAPK8IP3 CORO1A DUOX1 PAK1

1.57e-0450012111GO:0031252
GeneOntologyCellularComponentpostsynaptic specialization

TNIK MINK1 RAPGEF4 DGKB GRIA4 GRIK4 GRIN2A GRIN2B PAK1 PAK2 EPHA4

1.66e-0450312111GO:0099572
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIA4 GRIK4 GRIN2A GRIN2B

2.00e-04501214GO:0098878
GeneOntologyCellularComponentaxon terminus

ITSN1 RAPGEF4 GRIA4 GRIK4 GRIN2A GRIN2B EPHA4

2.24e-042101217GO:0043679
GeneOntologyCellularComponentpostsynaptic density membrane

DGKB GRIA4 GRIK4 GRIN2A GRIN2B EPHA4

3.08e-041571216GO:0098839
GeneOntologyCellularComponentlamellipodium

VIL1 ITSN1 APBB1 APBB2 CORO1B CORO1A PAK1

3.89e-042301217GO:0030027
GeneOntologyCellularComponentexcitatory synapse

SPTBN2 RAPGEF4 CHD4 GRIN2A GRIN2B

3.97e-041071215GO:0060076
GeneOntologyCellularComponentneuron projection terminus

ITSN1 RAPGEF4 GRIA4 GRIK4 GRIN2A GRIN2B EPHA4

4.20e-042331217GO:0044306
GeneOntologyCellularComponentdendrite

ITSN1 MINK1 RAPGEF4 DPYSL5 APBB1 GRIA4 GRIK4 GRIN2A GRIN2B MAPK8IP3 RPTOR PAK1 CNN3 EPHA4

4.46e-0485812114GO:0030425
GeneOntologyCellularComponentdendritic tree

ITSN1 MINK1 RAPGEF4 DPYSL5 APBB1 GRIA4 GRIK4 GRIN2A GRIN2B MAPK8IP3 RPTOR PAK1 CNN3 EPHA4

4.57e-0486012114GO:0097447
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIA4 GRIK4

4.91e-0461212GO:0032983
GeneOntologyCellularComponentpostsynapse

TNIK ITSN1 MINK1 SPTBN2 RAPGEF4 APBB1 DGKB GRIA4 GRIK4 GRIN2A GRIN2B PAK1 PAK2 CNN3 EPHA4

7.99e-04101812115GO:0098794
GeneOntologyCellularComponentpostsynaptic specialization membrane

DGKB GRIA4 GRIK4 GRIN2A GRIN2B EPHA4

1.13e-032011216GO:0099634
GeneOntologyCellularComponentpresynaptic membrane

ITSN1 APBB1 GRIA4 GRIK4 GRIN2A GRIN2B EPHA4

1.16e-032771217GO:0042734
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN2A GRIN2B

1.16e-0391212GO:0017146
GeneOntologyCellularComponentactin filament

GCK CORO1B CORO1A AFAP1 PAK1

1.61e-031461215GO:0005884
GeneOntologyCellularComponentpresynapse

TNIK ITSN1 SPTBN2 RAPGEF4 APBB1 GRIA4 GRIK4 GRIN2A GRIN2B SH3GLB1 CLCN4 SPHK1 EPHA4

1.88e-0388612113GO:0098793
GeneOntologyCellularComponentactin cytoskeleton

VIL1 ITSN1 SPTBN2 GCK CORO1B CORO1A AFAP1 PAK1 TNNI1 CNN3

1.92e-0357612110GO:0015629
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

SPTBN2 GRIN2A GRIN2B

1.97e-03431213GO:0098688
GeneOntologyCellularComponentterminal bouton

GRIA4 GRIK4 GRIN2A GRIN2B

2.35e-03961214GO:0043195
GeneOntologyCellularComponentpostsynaptic density, intracellular component

TNIK GRIN2A GRIN2B

2.87e-03491213GO:0099092
GeneOntologyCellularComponentgrowth cone

RAPGEF4 APBB1 APBB2 MAPK8IP3 PAK1 EPHA4

3.05e-032451216GO:0030426
GeneOntologyCellularComponentsite of polarized growth

RAPGEF4 APBB1 APBB2 MAPK8IP3 PAK1 EPHA4

3.58e-032531216GO:0030427
GeneOntologyCellularComponentpostsynaptic specialization, intracellular component

TNIK GRIN2A GRIN2B

4.19e-03561213GO:0099091
GeneOntologyCellularComponentCHD-type complex

CHD3 CHD4

4.27e-03171212GO:0090545
GeneOntologyCellularComponentNuRD complex

CHD3 CHD4

4.27e-03171212GO:0016581
DomainPAK_BD

PAK5 PAK4 PAK1 PAK2

2.57e-0861224IPR033923
DomainProtein_kinase_ATP_BS

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 BLK STK3 STK4 PAK1 PAK2 PRKD1 EPHA1 EPHA4

2.65e-0837912215IPR017441
DomainWASP_C

PAK5 PAK4 PAK1 PAK2

5.97e-0871224IPR011026
DomainProt_kinase_dom

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 BLK STK3 STK4 GUCY2C PAK1 PAK2 PRKD1 EPHA1 EPHA4

1.23e-0748912216IPR000719
DomainPROTEIN_KINASE_DOM

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 BLK STK3 STK4 GUCY2C PAK1 PAK2 PRKD1 EPHA1 EPHA4

1.37e-0749312216PS50011
DomainPROTEIN_KINASE_ATP

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 BLK STK3 STK4 PAK1 PAK2 PRKD1 EPHA1 EPHA4

3.19e-0745912215PS00107
DomainKinase-like_dom

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 BLK STK3 STK4 GUCY2C PAK1 PAK2 PRKD1 EPHA1 EPHA4

4.89e-0754212216IPR011009
DomainS_TKc

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 STK3 STK4 PAK1 PAK2 PRKD1 EPHA4

6.55e-0735912213SM00220
Domain-

PAK5 PAK4 PAK1 PAK2

8.24e-071212243.90.810.10
DomainPkinase

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 STK3 STK4 GUCY2C PAK1 PAK2 PRKD1

1.28e-0638112213PF00069
DomainPBD

PAK5 PAK4 PAK1 PAK2

2.97e-06161224SM00285
DomainPBD

PAK5 PAK4 PAK1 PAK2

3.86e-06171224PF00786
DomainSer/Thr_kinase_AS

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 STK3 STK4 PAK1 PAK2 PRKD1

3.90e-0635712212IPR008271
DomainANF_lig-bd_rcpt

GRIA4 GRIK4 GRIN2A GRIN2B GUCY2C

4.04e-06371225IPR001828
DomainANF_receptor

GRIA4 GRIK4 GRIN2A GRIN2B GUCY2C

4.04e-06371225PF01094
DomainPROTEIN_KINASE_ST

TNIK SLK SPEG PAK5 MINK1 PAK4 GRK1 STK3 STK4 PAK1 PAK2 PRKD1

4.49e-0636212212PS00108
DomainLig_chan-Glu_bd

GRIA4 GRIK4 GRIN2A GRIN2B

4.94e-06181224PF10613
DomainGlu/Gly-bd

GRIA4 GRIK4 GRIN2A GRIN2B

4.94e-06181224IPR019594
DomainLig_chan-Glu_bd

GRIA4 GRIK4 GRIN2A GRIN2B

4.94e-06181224SM00918
DomainIontro_rcpt

GRIA4 GRIK4 GRIN2A GRIN2B

4.94e-06181224IPR001320
DomainIono_rcpt_met

GRIA4 GRIK4 GRIN2A GRIN2B

4.94e-06181224IPR001508
DomainLig_chan

GRIA4 GRIK4 GRIN2A GRIN2B

4.94e-06181224PF00060
DomainPBPe

GRIA4 GRIK4 GRIN2A GRIN2B

4.94e-06181224SM00079
DomainPeripla_BP_I

GRIA4 GRIK4 GRIN2A GRIN2B GUCY2C

5.28e-06391225IPR028082
DomainCRIB

PAK5 PAK4 PAK1 PAK2

7.74e-06201224PS50108
DomainCRIB_dom

PAK5 PAK4 PAK1 PAK2

9.52e-06211224IPR000095
DomainMst1_SARAH_domain

STK3 STK4

4.23e-0521222IPR024205
DomainMst1_SARAH

STK3 STK4

4.23e-0521222PF11629
DomainSNF2_N

CHD3 CHD4 RAD54L2 ERCC6L2

5.41e-05321224IPR000330
DomainSNF2_N

CHD3 CHD4 RAD54L2 ERCC6L2

5.41e-05321224PF00176
DomainDAGKc

DGKB DGKE SPHK1

9.39e-05141223SM00046
DomainDiacylglycerol_kinase_cat_dom

DGKB DGKE SPHK1

1.17e-04151223IPR001206
DomainDAGK

DGKB DGKE SPHK1

1.17e-04151223PS50146
DomainDAGK_cat

DGKB DGKE SPHK1

1.17e-04151223PF00781
DomainCHD_N

CHD3 CHD4

1.26e-0431222IPR012958
DomainCHD_C2

CHD3 CHD4

1.26e-0431222IPR012957
DomainNMDAR2_C

GRIN2A GRIN2B

1.26e-0431222PF10565
DomainCHDCT2

CHD3 CHD4

1.26e-0431222PF08074
DomainCHDNT

CHD3 CHD4

1.26e-0431222PF08073
DomainDUF1086

CHD3 CHD4

1.26e-0431222IPR009462
DomainDUF1087

CHD3 CHD4

1.26e-0431222IPR009463
DomainNMDAR2_C

GRIN2A GRIN2B

1.26e-0431222IPR018884
DomainDUF1087

CHD3 CHD4

1.26e-0431222PF06465
DomainDUF1086

CHD3 CHD4

1.26e-0431222PF06461
DomainDUF1087

CHD3 CHD4

1.26e-0431222SM01147
DomainDUF1086

CHD3 CHD4

1.26e-0431222SM01146
DomainWD40_repeat_dom

MED16 EML6 CORO1B MAPK8IP3 CORO1A FBXW8 NWD2 RPTOR TLE3

1.46e-042971229IPR017986
DomainNAD/diacylglycerol_kinase

DGKB DGKE SPHK1

1.73e-04171223IPR016064
Domain-

MED16 EML6 CORO1B MAPK8IP3 CORO1A FBXW8 NWD2 RPTOR TLE3

3.41e-0433312292.130.10.10
DomainWD40/YVTN_repeat-like_dom

MED16 EML6 CORO1B MAPK8IP3 CORO1A FBXW8 NWD2 RPTOR TLE3

3.56e-043351229IPR015943
DomainWD40

MED16 EML6 CORO1B CORO1A FBXW8 NWD2 RPTOR TLE3

3.81e-042681228SM00320
DomainWD40_repeat

MED16 EML6 CORO1B CORO1A FBXW8 NWD2 RPTOR TLE3

4.20e-042721228IPR001680
DomainWD_REPEATS_1

MED16 EML6 CORO1B CORO1A FBXW8 NWD2 RPTOR TLE3

4.85e-042781228PS00678
DomainWD_REPEATS_2

MED16 EML6 CORO1B CORO1A FBXW8 NWD2 RPTOR TLE3

4.97e-042791228PS50082
DomainWD_REPEATS_REGION

MED16 EML6 CORO1B CORO1A FBXW8 NWD2 RPTOR TLE3

4.97e-042791228PS50294
DomainHaem_d1

EML6 KMT2A

6.24e-0461222IPR011048
DomainWD40_repeat_CS

EML6 CORO1B CORO1A FBXW8 NWD2 TLE3

7.31e-041641226IPR019775
DomainHMG_box_dom

TOX CHD3 CHD4 SMARCE1

8.63e-04651224IPR009071
DomainTrimer_CC

CORO1B CORO1A

8.70e-0471222IPR015049
DomainDUF1899

CORO1B CORO1A

8.70e-0471222IPR015048
DomainTrimer_CC

CORO1B CORO1A

8.70e-0471222PF08954
DomainDUF1899

CORO1B CORO1A

8.70e-0471222PF08953
DomainCoronin

CORO1B CORO1A

8.70e-0471222IPR015505
DomainDUF1899

CORO1B CORO1A

8.70e-0471222SM01166
DomainGDA1_CD39_NTPase

ENTPD6 ENTPD5

1.15e-0381222IPR000407
DomainGDA1_CD39

ENTPD6 ENTPD5

1.15e-0381222PF01150
DomainGDA1_CD39_NTPASE

ENTPD6 ENTPD5

1.15e-0381222PS01238
DomainSARAH

STK3 STK4

1.48e-0391222PS50951
DomainSARAH_dom

STK3 STK4

1.48e-0391222IPR011524
DomainDNA/RNA_helicase_DEAH_CS

CHD3 CHD4 ERCC6L2

1.53e-03351223IPR002464
DomainWD40

MED16 EML6 CORO1B CORO1A FBXW8 RPTOR TLE3

1.57e-032591227PF00400
DomainDAGK_acc

DGKB DGKE

1.84e-03101222PF00609
DomainHMG_BOX_1

TOX SMARCE1

1.84e-03101222PS00353
DomainDiacylglycerol_kin_accessory

DGKB DGKE

1.84e-03101222IPR000756
DomainDAGKa

DGKB DGKE

1.84e-03101222SM00045
DomainDEAH_ATP_HELICASE

CHD3 CHD4 ERCC6L2

1.94e-03381223PS00690
DomainSPRY

TRIM15 TRIML2 FSD1 TRIM47

3.36e-03941224PF00622
DomainSPRY_dom

TRIM15 TRIML2 FSD1 TRIM47

3.36e-03941224IPR003877
DomainB30.2/SPRY

TRIM15 TRIML2 FSD1 TRIM47

3.49e-03951224IPR001870
DomainB302_SPRY

TRIM15 TRIML2 FSD1 TRIM47

3.49e-03951224PS50188
DomainRECEPTOR_TYR_KIN_V_2

EPHA1 EPHA4

3.66e-03141222PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHA1 EPHA4

3.66e-03141222PS00790
DomainTyr_kinase_rcpt_V_CS

EPHA1 EPHA4

3.66e-03141222IPR001426
DomainATPase_dyneun-rel_AAA

VWA8 DNAH2

3.66e-03141222IPR011704
DomainEphA2_TM

EPHA1 EPHA4

3.66e-03141222PF14575
DomainEphrin_rcpt_lig-bd_dom

EPHA1 EPHA4

3.66e-03141222IPR001090
DomainEph_TM

EPHA1 EPHA4

3.66e-03141222IPR027936
DomainEPH_lbd

EPHA1 EPHA4

3.66e-03141222SM00615
DomainEphrin_lbd

EPHA1 EPHA4

3.66e-03141222PF01404
DomainTyr_kinase_ephrin_rcpt

EPHA1 EPHA4

3.66e-03141222IPR016257
DomainEPH_LBD

EPHA1 EPHA4

3.66e-03141222PS51550
DomainCNH

TNIK MINK1

3.66e-03141222SM00036
DomainAAA_5

VWA8 DNAH2

3.66e-03141222PF07728
DomainPRY

TRIM15 TRIML2 TRIM47

3.80e-03481223SM00589
DomainPRY

TRIM15 TRIML2 TRIM47

3.80e-03481223IPR006574
DomainCNH

TNIK MINK1

4.20e-03151222PF00780
DomainCNH

TNIK MINK1

4.20e-03151222PS50219
DomainCNH_dom

TNIK MINK1

4.20e-03151222IPR001180
DomainHelicase_C

CHD3 CHD4 RAD54L2 ERCC6L2

5.33e-031071224PF00271
DomainHELICc

CHD3 CHD4 RAD54L2 ERCC6L2

5.33e-031071224SM00490
PathwayREACTOME_ACTIVATION_OF_RAC1

PAK5 PAK4 PAK1 PAK2

1.06e-0613904M6322
PathwayWP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS

PAK5 PAK4 STK3 PAK1 PAK2

1.18e-0547905M39829
PathwayKEGG_AXON_GUIDANCE

PAK5 PAK4 DPYSL5 PAK1 PAK2 EPHA1 EPHA4

1.82e-05129907M5539
PathwayREACTOME_EPH_EPHRIN_SIGNALING

ITSN1 GRIN2B PAK1 PAK2 EPHA1 EPHA4

2.63e-0592906M27201
PathwayBIOCARTA_AGR_PATHWAY

PAK5 PAK4 PAK1 PAK2

5.52e-0533904M6220
PathwayREACTOME_EPH_EPHRIN_SIGNALING

ITSN1 PAK1 PAK2 EPHA1 EPHA4

5.79e-0565905MM14911
PathwaySIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES

PAK5 PAK4 PAK1 PAK2

6.99e-0535904M16801
PathwayREACTOME_RHOH_GTPASE_CYCLE

PAK5 PAK4 PAK1 PAK2

7.83e-0536904MM15603
PathwayREACTOME_RHOH_GTPASE_CYCLE

PAK5 PAK4 PAK1 PAK2

8.73e-0537904M41813
PathwayWP_NEURAL_CREST_CELL_MIGRATION_DURING_DEVELOPMENT

PAK5 PAK4 PAK1 PAK2

1.19e-0440904M39798
PathwayWP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER

PAK5 PAK4 PAK1 PAK2

1.58e-0443904M39788
PathwayWP_RAS_SIGNALING

PAK5 PAK4 GRIN2A GRIN2B STK4 PAK1 PAK2

1.73e-04184907M39764
PathwaySIG_CHEMOTAXIS

PAK5 PAK4 PAK1 PAK2

1.89e-0445904M5193
PathwayWP_NRXN1_DELETION_SYNDROME

GRIA4 GRIN2A GRIN2B

1.92e-0418903M48098
PathwayREACTOME_SYNAPTIC_ADHESION_LIKE_MOLECULES

GRIA4 GRIN2A GRIN2B

3.08e-0421903M27736
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIA4 GRIN2A GRIN2B

3.08e-0421903M838
PathwayWP_HIPPOYAP_SIGNALING

TNIK MINK1 STK3

3.55e-0422903M39821
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

3.98e-045902M47667
PathwayREACTOME_CDC42_GTPASE_CYCLE

ITSN1 PAK5 PAK4 PAK1 PAK2 FMNL1

4.67e-04155906M41808
PathwayREACTOME_RHOQ_GTPASE_CYCLE

ITSN1 PAK4 PAK1 PAK2

5.07e-0458904MM15602
PathwayREACTOME_RHOQ_GTPASE_CYCLE

ITSN1 PAK4 PAK1 PAK2

5.41e-0459904M41812
PathwayWP_MET_IN_TYPE_1_PAPILLARY_RENAL_CELL_CARCINOMA

PAK5 PAK4 PAK1 PAK2

5.41e-0459904M39750
PathwayWP_MAPK_SIGNALING_PATHWAY

MINK1 GCK MAPK8IP3 STK3 PAK1 PAK2

5.52e-04160906MM15990
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN2A GRIN2B

5.95e-046902M47668
PathwayREACTOME_REGULATION_OF_PTEN_GENE_TRANSCRIPTION

CHD3 CHD4 RPTOR

6.59e-0427903MM15537
PathwaySIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES

PAK5 PAK4 PAK1 PAK2

8.76e-0467904M295
PathwayPID_P38_ALPHA_BETA_PATHWAY

BLK PAK1 PAK2

9.02e-0430903M76
PathwayBIOCARTA_AGR_PATHWAY

PAK4 PAK1 PAK2

9.94e-0431903MM1343
PathwayKEGG_RENAL_CELL_CARCINOMA

PAK5 PAK4 PAK1 PAK2

1.03e-0370904M13266
PathwayWP_HIPPOMERLIN_SIGNALING_DYSREGULATION

PAK5 PAK4 STK3 PAK1 PAK2

1.05e-03121905M39823
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD6 ENTPD5

1.10e-038902M27737
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD6 ENTPD5

1.10e-038902MM15486
PathwayPID_EPHA_FWDPATHWAY

BLK EPHA1 EPHA4

1.30e-0334903M177
PathwayREACTOME_NERVOUS_SYSTEM_DEVELOPMENT

ITSN1 SPTBN2 DPYSL5 PAK1 PAK2 EPHA1 EPHA4

1.39e-03261907MM15676
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK SLK CCT3 ITSN1 PAK5 MINK1 SPTBN2 RAPGEF4 GRIA4 CHD4 GRIN2A CORO1B GRIN2B SIPA1 MAPK8IP3 UBE2V1 TMEM259 RPTOR PAK1 PAK2 PRKD1 CABIN1 TP53BP1 EPHA4

4.01e-149631222428671696
Pubmed

Targeted disruption of the gene for the PAK5 kinase in mice.

PAK5 PAK4 PAK1 PAK2

2.15e-096122414517284
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SLK HYOU1 CCT3 ITSN1 MINK1 SPTBN2 RAPGEF4 DPYSL5 DGKB CHD3 GRIN2A CORO1B GRIN2B SIPA1 MAPK8IP3 STK4 CORO1A NWD2 AFAP1 RPTOR KCTD10 KMT2A

5.11e-0914311222237142655
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

TNIK ITSN1 ANGEL1 APBB1 APBB2 TFIP11 SPAG5 SMARCE1

1.10e-08120122831413325
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TNIK SLK CCT3 PAK4 APBB1 TFIP11 CHD3 CHD4 CORO1B MCCC1 SPAG5 STK4 PAK2 KMT2A SMARCE1 CNN3 TP53BP1

3.12e-089341221733916271
Pubmed

p21-Activated Kinases 1, 2 and 4 in Endometrial Cancers: Effects on Clinical Outcomes and Cell Proliferation.

PAK4 PAK1 PAK2

4.21e-083122326218748
Pubmed

Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST).

STK3 STK4 PAK2

4.21e-083122311805089
Pubmed

Protein kinase D1 (PKD1) phosphorylation on Ser203 by type I p21-activated kinase (PAK) regulates PKD1 localization.

PAK1 PAK2 PRKD1

4.21e-083122328408623
Pubmed

Amyloid-β Receptors: The Good, the Bad, and the Prion Protein.

GRIA4 GRIN2A GRIN2B

1.68e-074122326719327
Pubmed

Pak to the future.

PAK4 PAK1 PAK2

1.68e-074122310461188
Pubmed

Regulated internalization of NMDA receptors drives PKD1-mediated suppression of the activity of residual cell-surface NMDA receptors.

GRIN2A GRIN2B PRKD1

1.68e-074122326584860
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

TNIK SLK MINK1 SPTBN2 RAPGEF4 GRIA4 GRIN2A GRIN2B UBE2V1

2.76e-07251122927507650
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

PAK4 DNAH2 DGKB DGKE GCK GRK1 BLK STK3 STK4 SULT1B1 KCTD10 PAK1 PAK2 KMT2A

3.02e-077301221434857952
Pubmed

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.

PAK4 PAK1 PAK2

4.19e-075122323509247
Pubmed

NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses.

GRIK4 GRIN2A GRIN2B

4.19e-075122319726645
Pubmed

YSK1, a novel mammalian protein kinase structurally related to Ste20 and SPS1, but is not involved in the known MAPK pathways.

MINK1 STK4 PAK1

8.36e-07612239160885
Pubmed

Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation.

GRIN2A GRIN2B PAK1 PAK2

1.21e-0623122430992372
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIA4 GRIK4 GRIN2A GRIN2B

1.45e-0624122435746896
Pubmed

Transmembrane topology of the glutamate receptor subunit GluR6.

GRIA4 GRIN2A GRIN2B

2.33e-06812238163463
Pubmed

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.

GRIA4 GRIK4 GRIN2B

3.48e-069122334100982
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TNPO1 ZNF609 PAK4 DPYSL5 DGKE CORO1B SPAG5 STK3 STK4 CORO1A OXA1L SH3GLB1 UBE2V1 RPTOR UQCC1 PRKD1 TP53BP1

3.83e-0613211221727173435
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

SLK MED16 PAK5 MINK1 PAK4 CHD4 F13A1 BLK STK3 STK4 SH3GLB1 KMT2A PRKD1 EPHA4

3.99e-069101221436736316
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

TNPO1 SLK CCT3 ITSN1 APBB1 CORO1B ARL1 SLC12A2 DHRS7 CNN3

4.43e-064491221031732153
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TNPO1 TNIK HYOU1 VWA8 ITSN1 MINK1 SPTBN2 PAK4 APBB1 DGKE TFIP11 HSPA12B ARL1 OXA1L SLC12A2 DHRS7 VPS13B TP53BP1

4.52e-0614871221833957083
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

CCT3 ITSN1 TFIP11 GRIN2A CORO1B RAD54L2 SIPA1 SPAG5 MAPK8IP3 CORO1A KCNN1

4.80e-065601221121653829
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

TNPO1 ZNF609 MED16 DGKE TFIP11 CHD4 ARL1 OXA1L SLC12A2 ARL6IP1 RPTOR DHRS7 UQCC1 IL17RA ZCCHC7 TP53BP1

5.02e-0612031221629180619
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

TNPO1 VWA8 MED16 SPTBN2 DPYSL5 BUD13 TFIP11 CHD4 EHBP1L1 NWD2 AFAP1 OXA1L DHRS7 KCTD10 SMARCE1

6.21e-0610821221538697112
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PAK5 MINK1 PAK4 DPYSL5 APBB1 FSD1 MCCC1 PTPN21 STK3 STK4 SLC12A2 RPTOR KMT2A

1.10e-058611221336931259
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TNIK VWA8 MINK1 APBB1 GRIA4 GRIN2A CORO1B GRIN2B MCCC1 MAPK8IP3 CORO1A UBE2V1 RPTOR KCTD10 TP53BP1

1.14e-0511391221536417873
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ITSN1 SPTBN2 RAPGEF4 APBB1 APBB2 TFIP11 CHD4 GRIN2B RAD54L2 MAPK8IP3 FAIM PAK1 KCNN1 PAK2 SMARCE1 CABIN1

1.14e-0512851221635914814
Pubmed

Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol.

GRIA4 GRIK4 GRIN2B

1.17e-0513122320859245
Pubmed

Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.

CHD3 CHD4

1.22e-05212227560064
Pubmed

Activation of PAK1/2 during the shedding of platelet microvesicles.

PAK1 PAK2

1.22e-052122220523167
Pubmed

The glutamate receptor GluN2 subunit regulates synaptic trafficking of AMPA receptors in the neonatal mouse brain.

GRIN2A GRIN2B

1.22e-052122225131300
Pubmed

Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms.

GRIN2A GRIN2B

1.22e-052122220921396
Pubmed

Non-canonical role of Hippo tumor suppressor serine/threonine kinase 3 STK3 in prostate cancer.

STK3 STK4

1.22e-052122234450249
Pubmed

MST1/2 in PDGFRα+ cells negatively regulates TGF-β-induced myofibroblast accumulation in renal fibrosis.

STK3 STK4

1.22e-052122235253468
Pubmed

The GRIN2B and GRIN2A Gene Variants Are Associated With Continuous Performance Test Variables in ADHD.

GRIN2A GRIN2B

1.22e-052122227199241
Pubmed

The role of NMDAR subtypes and charge transfer during hippocampal LTP induction.

GRIN2A GRIN2B

1.22e-052122216901514
Pubmed

FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness.

APBB1 APBB2

1.22e-052122225757569
Pubmed

Inhibition of P21-activated kinases 1 and 4 synergistically suppresses the growth of pancreatic cancer by stimulating anti-tumour immunity.

PAK4 PAK1

1.22e-052122238797819
Pubmed

Specific involvement of postsynaptic GluN2B-containing NMDA receptors in the developmental elimination of corticospinal synapses.

GRIN2A GRIN2B

1.22e-052122220696923
Pubmed

NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.

GRIN2A GRIN2B

1.22e-052122223618906
Pubmed

Both NR2A and NR2B subunits of the NMDA receptor are critical for long-term potentiation and long-term depression in the lateral amygdala of horizontal slices of adult mice.

GRIN2A GRIN2B

1.22e-052122219474217
Pubmed

Inactivation of MST1/2 Controls Macrophage Polarization to Affect Macrophage-Related Disease via YAP and Non-YAP Mechanisms.

STK3 STK4

1.22e-052122238250155
Pubmed

p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma.

PAK4 PAK1

1.22e-052122233414491
Pubmed

FE65 and FE65L1 share common synaptic functions and genetically interact with the APP family in neuromuscular junction formation.

APBB1 APBB2

1.22e-052122227734846
Pubmed

Importance of the GluN2B carboxy-terminal domain for enhancement of social memories.

GRIN2A GRIN2B

1.22e-052122226179233
Pubmed

STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.

STK3 STK4

1.22e-052122226457732
Pubmed

Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin.

TLR5 PRKD1

1.22e-052122217442957
Pubmed

The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.

CHD3 CHD4

1.22e-05212227575689
Pubmed

Lack of NMDA receptor subtype selectivity for hippocampal long-term potentiation.

GRIN2A GRIN2B

1.22e-052122216033900
Pubmed

Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesions.

PAK1 PAK2

1.22e-052122215047871
Pubmed

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.

GRIN2A GRIN2B

1.22e-052122238214768
Pubmed

Stimulation of Neurite Outgrowth in Cerebrocortical Neurons by Sodium Channel Activator Brevetoxin-2 Requires Both N-Methyl-D-aspartate Receptor 2B (GluN2B) and p21 Protein (Cdc42/Rac)-Activated Kinase 1 (PAK1).

GRIN2B PAK1

1.22e-052122236135748
Pubmed

[Different distribution of NMDA receptor subunits in cortex contributes to selective vulnerability of motor neurons in amyotrophic lateral sclerosis].

GRIN2A GRIN2B

1.22e-052122221503117
Pubmed

Functional contributions of synaptically localized NR2B subunits of the NMDA receptor to synaptic transmission and long-term potentiation in the adult mouse CNS.

GRIN2A GRIN2B

1.22e-052122218372311
Pubmed

Position- and polarity-dependent Hippo signaling regulates cell fates in preimplantation mouse embryos.

STK3 STK4

1.22e-052122225986053
Pubmed

Effects of GluN2A and GluN2B gain-of-function epilepsy mutations on synaptic currents mediated by diheteromeric and triheteromeric NMDA receptors.

GRIN2A GRIN2B

1.22e-052122232247039
Pubmed

Hippo-YAP signaling controls lineage differentiation of mouse embryonic stem cells through modulating the formation of super-enhancers.

STK3 STK4

1.22e-052122232510157
Pubmed

Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene.

STK3 STK4

1.22e-052122219878874
Pubmed

Separate functional properties of NMDARs regulate distinct aspects of spatial cognition.

GRIN2A GRIN2B

1.22e-052122229764972
Pubmed

Increasing the GluN2A/GluN2B Ratio in Neurons of the Mouse Basal and Lateral Amygdala Inhibits the Modification of an Existing Fear Memory Trace.

GRIN2A GRIN2B

1.22e-052122227605622
Pubmed

Disease-associated GRIN protein truncating variants trigger NMDA receptor loss-of-function.

GRIN2A GRIN2B

1.22e-052122233043365
Pubmed

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

GRIN2A GRIN2B

1.22e-052122230355491
Pubmed

Evidence for the presence of cGMP-dependent protein kinase-II in human distal colon and in T84, the colonic cell line.

SLC12A2 GUCY2C

1.22e-052122211042348
Pubmed

N-methyl-D-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease.

GRIN2A GRIN2B

1.22e-052122212127670
Pubmed

Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.

GRIN2A GRIN2B

1.22e-052122220890276
Pubmed

Hippo pathway regulation by cell morphology and stress fibers.

STK3 STK4

1.22e-052122221831922
Pubmed

Roles of NMDA receptor NR2A and NR2B subtypes for long-term depression in the anterior cingulate cortex.

GRIN2A GRIN2B

1.22e-052122216045501
Pubmed

Mammalian sterile 20 kinase 1 and 2 are important regulators of hematopoietic stem cells in stress condition.

STK3 STK4

1.22e-052122229343826
Pubmed

The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport.

PAK1 PAK2

1.22e-052122232597567
Pubmed

The subcellular localization of type I p21-activated kinases is controlled by the disordered variable region and polybasic sequences.

PAK1 PAK2

1.22e-052122231391252
Pubmed

NR2A- and NR2B-NMDA receptors and drebrin within postsynaptic spines of the hippocampus correlate with hunger-evoked exercise.

GRIN2A GRIN2B

1.22e-052122227915379
Pubmed

Lupus autoantibodies act as positive allosteric modulators at GluN2A-containing NMDA receptors and impair spatial memory.

GRIN2A GRIN2B

1.22e-052122232179753
Pubmed

Virally mediated knock-down of NR2 subunits ipsilateral to the deprived eye blocks ocular dominance plasticity.

GRIN2A GRIN2B

1.22e-052122216944113
Pubmed

Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor.

GRIN2A GRIN2B

1.22e-05212229822733
Pubmed

NR2A and NR2B receptor gene variations modify age at onset in Huntington disease.

GRIN2A GRIN2B

1.22e-052122215742215
Pubmed

Protein kinase D regulates cofilin activity through p21-activated kinase 4.

PAK4 PRKD1

1.22e-052122221832093
Pubmed

Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.

GRIN2A GRIN2B

1.22e-052122237657442
Pubmed

Individual NMDA receptor GluN2 subunit signaling domains differentially regulate the postnatal maturation of hippocampal excitatory synaptic transmission and plasticity but not dendritic morphology.

GRIN2A GRIN2B

1.22e-052122238813758
Pubmed

PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions.

PAK1 PAK2

1.22e-052122231748572
Pubmed

Transcription factor TOX maintains the expression of Mst1 in controlling the early mouse NK cell development.

TOX STK4

1.22e-052122237153735
Pubmed

Dual Role of NMDAR Containing NR2A and NR2B Subunits in Alzheimer's Disease.

GRIN2A GRIN2B

1.22e-052122238731978
Pubmed

Differential role for PAK1 and PAK4 during the invadopodia lifecycle.

PAK4 PAK1

1.22e-052122228301299
Pubmed

Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b.

CORO1B CORO1A

1.22e-052122221844203
Pubmed

Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases.

PAK1 PAK2

1.22e-052122219435845
Pubmed

Differential Nanoscale Topography and Functional Role of GluN2-NMDA Receptor Subtypes at Glutamatergic Synapses.

GRIN2A GRIN2B

1.22e-052122230269991
Pubmed

Downregulation of hippocampal NR2A/2B subunits related to cognitive impairment in a pristane-induced lupus BALB/c mice.

GRIN2A GRIN2B

1.22e-052122231498792
Pubmed

Age-Dependent Changes in Synaptic NMDA Receptor Composition in Adult Human Cortical Neurons.

GRIN2A GRIN2B

1.22e-052122232191258
Pubmed

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions.

GRIN2A GRIN2B

1.22e-052122231807283
Pubmed

Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling.

STK3 STK4

1.22e-052122219484742
Pubmed

The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis.

GRIN2A GRIN2B

1.22e-052122226500840
Pubmed

Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis.

STK3 STK4

1.22e-052122211964314
Pubmed

Effect of Inactivation of Mst1 and Mst2 in the Mouse Adrenal Cortex.

STK3 STK4

1.22e-052122236405866
Pubmed

Chronic early postnatal scream sound stress induces learning deficits and NMDA receptor changes in the hippocampus of adult mice.

GRIN2A GRIN2B

1.22e-052122227015584
Pubmed

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation.

GRIN2A GRIN2B

1.22e-052122219806658
Pubmed

STK3/STK4 signalling in adipocytes regulates mitophagy and energy expenditure.

STK3 STK4

1.22e-052122233758424
Pubmed

Subtype selective NMDA receptor antagonists induce recovery of synapses lost following exposure to HIV-1 Tat.

GRIN2A GRIN2B

1.22e-052122222142193
Pubmed

Conformational rearrangement of the NMDA receptor amino-terminal domain during activation and allosteric modulation.

GRIN2A GRIN2B

1.22e-052122233976221
InteractionSRC interactions

VIL1 TRIM15 FSD1 CHD4 GRIN2A GRIN2B PTPN21 MAPK8IP3 BLK AFAP1 GUCY2C SPHK1 CCNA1 PAK2 KMT2A SMARCE1 PRKD1 EPHA4

7.86e-0866412018int:SRC
InteractionSHANK3 interactions

TNIK SLK HYOU1 CCT3 ITSN1 SPTBN2 RAPGEF4 TFIP11 GRIN2A GRIN2B SIPA1 SPAG5 MAPK8IP3

8.28e-0649612013int:SHANK3
InteractionTNIK interactions

TNIK PAK5 MINK1 SPTBN2 RAPGEF4 GRIN2A GRIN2B HSPA12B SMARCE1 CABIN1 TP53BP1

1.76e-0538112011int:TNIK
InteractionKCTD13 interactions

SLK HYOU1 CCT3 ITSN1 MINK1 SPTBN2 RAPGEF4 DPYSL5 DGKB CHD3 GRIN2A CORO1B GRIN2B SIPA1 MAPK8IP3 STK4 CORO1A NWD2 AFAP1 RPTOR KCTD10 KMT2A

2.28e-05139412022int:KCTD13
InteractionISX interactions

ZNF609 MCCC1 RAD54L2 TLE3

3.32e-05311204int:ISX
Cytoband12p12

GRIN2B GUCY2C

5.36e-0413122212p12
Cytoband5q23.3

ADAMTS19 SLC12A2

6.24e-041412225q23.3
Cytoband3p21.2

PPM1M RAD54L2

1.16e-031912223p21.2
Cytoband8q22.2

STK3 VPS13B

1.71e-032312228q22.2
Cytoband3q22.3

NME9 FAIM

2.02e-032512223q22.3
CytobandEnsembl 112 genes in cytogenetic band chr11q23

HYOU1 BUD13 GRIK4 KMT2A

2.90e-032201224chr11q23
GeneFamilyWD repeat domain containing

MED16 EML6 CORO1B CORO1A FBXW8 RPTOR TLE3

1.06e-04262757362
GeneFamilyWD repeat domain containing|Coronins

CORO1B CORO1A

3.52e-047752495
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2A GRIN2B

3.52e-0477521201
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKB DGKE

7.48e-04107521178
GeneFamilyPHD finger proteins|NuRD complex

CHD3 CHD4

1.09e-03127521305
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA1 EPHA4

1.50e-03147521095
GeneFamilyHeat shock 70kDa proteins

HYOU1 HSPA12B

2.22e-0317752583
ToppCellTCGA-Colorectal|World / Sample_Type by Project: Shred V9

VIL1 TRIM15 PIGZ SULT1B1 CLCA1 SLC12A2 GUCY2C

3.85e-071661227c018cd8c7a82251c67e3dc812d4d21e527a43456
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 TOX APBB2 STK3 PRKD1 ZCCHC7 VPS13B

1.17e-061961227ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAK5 EML6 RAPGEF4 DGKB GRIN2A GRIN2B PAK1

1.26e-0619812274ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 PAK5 DGKB GRIA4 GRIN2B TRPM8

5.29e-061601226c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS19 PAK5 DGKB GRIA4 GRIN2B TRPM8

5.29e-06160122625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellHealthy_Control-Lymphoid-B-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

QRICH2 BLK CORO1A HMCN2 GUCY2C EPHA4

5.89e-061631226d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCellHealthy_Control-Lymphoid-B|Healthy_Control / Condition, Lineage, Cell class and cell subclass

QRICH2 BLK CORO1A HMCN2 GUCY2C EPHA4

5.89e-0616312260f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGPAT4 CORO1A SLC12A2 ADAMDEC1 IL17RA FMNL1

7.00e-0616812264b5be7c6662eceddf90a65015f12908278d1664e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGPAT4 CORO1A SLC12A2 ADAMDEC1 IL17RA FMNL1

7.00e-061681226689c41f6e9f65381570991cc311cba49a57ec955
ToppCell343B-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

VIL1 MINK1 EML6 FSD1 BLK STK4

7.25e-061691226e68e6c24606fd46eca6f86bb63fa86ea17879ae2
ToppCellIonocyte-iono-1|World / Class top

RAPGEF4 ABCC6 SLC12A2 SPHK1 RPTOR CNN3

7.25e-0616912264b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAK5 SPTBN2 DPYSL5 FSD1 GRIK4 CCNA1

9.13e-061761226bfea433544c6d6b8ad55e50ca94c5574460c2e0b
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-neurons_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAK5 SPTBN2 DPYSL5 FSD1 GRIK4 CCNA1

9.13e-0617612263c78dee7e1111a579fde6d401b9ecb4d5b8e782f
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TOX PAK5 HSPA12B CLCA1 TRIM47 CNN3

1.37e-051891226d17e8467699c7ca7694a313c26111f085df5204e
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

F13A1 ADAMDEC1 SPHK1 PAK1 KCNN1 CCNA1

1.63e-0519512266ba23e19801305e071b0e4aaf1ee6f53f3b027d3
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

F13A1 ADAMDEC1 SPHK1 PAK1 KCNN1 CCNA1

1.63e-0519512267209babdff96c93cd52cfe5d5cfd7e3c0274d8dd
ToppCellMild_COVID-19-Myeloid-cDC|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

F13A1 ADAMDEC1 SPHK1 PAK1 KCNN1 CCNA1

1.63e-05195122624149bb6933135b1a0a5c7f505914942b3782c3a
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGPAT4 APBB1 PIGZ SLC12A2 PAK1 TNNI1

1.78e-051981226a183afe4c2034323f77abfa080f359d67da35e8f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAK5 EML6 GRIN2A GRIN2B PAK1 EPHA4

1.78e-0519812268ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF609 TOX APBB2 STK3 PRKD1 VPS13B

1.78e-0519812261996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MED16 MINK1 APBB2 FBXW8 KANK4 CREB3L2

1.89e-0520012265ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCellMyeloid-E_(Neutrophils)|World / shred on cell class and cell subclass (v4)

CORO1A DHRS7 ABTB1 IL17RA FMNL1

4.97e-0514512256ae7dbc62116b4d0610fb55703679488e8da4733
ToppCellHealthy-B_cell|World / disease group, cell group and cell class

TRIM15 TOX HSPA12B BLK ZCCHC7

5.13e-051461225588359d3df6ad7090b7fa6c7f8d29cc1717e7f4f
ToppCellHealthy-B_cell|Healthy / disease group, cell group and cell class

TRIM15 TOX HSPA12B BLK ZCCHC7

6.41e-0515312257f82cd61b3f1ebaee3e4bbf68ba858a67c2065e7
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 CHD3 GRIK4 GRIN2A GRIN2B

6.82e-05155122572a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCellIIH-CD8-memory_CD4|IIH / Condition, Cell_class and T cell subcluster

DGKB NME9 SPAG5 MAPK8IP3 FBXW8

7.03e-051561225e312fc4317d966fb2b570d1a4a3aa865f781ea93
ToppCellfacs-Heart-RA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 TRIM15 SULT1B1 GUCY2C TNNI1

8.64e-05163122513557be854878abc1bcdab909b49b8292d064145
ToppCellfacs-Heart-RA-18m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 TRIM15 SULT1B1 GUCY2C TNNI1

8.64e-0516312256c1d1646410e785886d2de103b4b12f73e91edff
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

BLK HMCN2 SHPK SLC38A7 EPHA4

9.16e-0516512253d2acdae0dd2b79a15f74158e8e566ce22b4218e
ToppCelldroplet-Kidney-nan-24m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGPAT4 DNAH2 CORO1A ADAMDEC1 IL17RA

9.69e-0516712252ee1660be117e20f24557522345572d11cbee813
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

SPEG DGKB GRIA4 ARL1 HMCN2

9.69e-051671225c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 RAPGEF4 SULT1B1 AFAP1 SPHK1

9.69e-051671225d7fe24cdc4b55a9555ce9e20699f5036b88148e9
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF609 MINK1 AGPAT4 DNAH2 IL17RA

9.96e-051681225e979a4fbeb9f21048b47d69e6da75c57650697f2
ToppCelldroplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGPAT4 PPM1M F13A1 CORO1A FMNL1

9.96e-051681225ce5e92a1df3acfa5cd8d5a134e4af231dc592a13
ToppCelldroplet-Liver-Npc-18m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGPAT4 PPM1M F13A1 CORO1A FMNL1

9.96e-05168122522c89d4eb44573f6301069ec7ca7cbd0dd958403
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MAN2B2 HMCN2 SHPK SLC38A7 EPHA4

1.08e-041711225e59afa0a773dca3b9c208d17510ea55703b42598
ToppCellfacs-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

F13A1 CORO1A PAK1 IL17RA FMNL1

1.08e-0417112254ad28ecfde3d529a09b80be908c446bd5274518e
ToppCelldroplet-Lung-nan-21m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGPAT4 CORO1A SLC12A2 IL17RA FMNL1

1.11e-04172122551bea97564a33f0060c546c9be4bf8bf8f1660f6
ToppCelldroplet-Lung-nan-21m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGPAT4 CORO1A SLC12A2 IL17RA FMNL1

1.11e-041721225be4dd4ba8d7a651677c797c25fd75f14e627415a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Non-classical_Monocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PPM1M CORO1A EHBP1L1 SPHK1 FMNL1

1.21e-041751225e991ffa4d1d278a011592b9915cd35fe76db20cc
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK SEC16B TOX ENTPD6 KMT2A

1.24e-041761225dca70f309af24421f8dc708cbd88512814b8e79e
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK SEC16B ENTPD6 ERCC6L2 KMT2A

1.27e-0417712259edfb50856f5e10672ab194ce0076d6a190e64de
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VIL1 APBB2 CLCA1 TRIM47 CNN3

1.27e-0417712256f6cf93893daac6ae228df36219ee3acf8de8f97
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 TRIML2 RAPGEF4 SULT1B1 AFAP1

1.38e-04180122527e8bbee388e64dd79d70b160b76d45b1f398006
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX GRIN2A GRIN2B SHPK KANK4

1.45e-041821225a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CORO1A EHBP1L1 SPHK1 TLE3 FMNL1

1.49e-041831225cff3197e9ff401362501db2317c86adc6d24b595
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CORO1A EHBP1L1 SPHK1 TLE3 FMNL1

1.49e-041831225f803dd2881ceaed6327e21a1a51bc3d3ccf4b5f8
ToppCellDendritic_Cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

F13A1 STK4 CORO1A PAK1 FMNL1

1.49e-041831225dd09e39e8ca282ff0f470e0652d519e190badd0b
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CORO1A EHBP1L1 SPHK1 TLE3 FMNL1

1.49e-0418312254bd6883daf2dbe8c1b49b776b48d41f9890d1cb4
ToppCellPBMC-Control-cDC_10|Control / Compartment, Disease Groups and Clusters

ADAMDEC1 CCNA1 PRKD1 TNNI1 CNN3

1.56e-0418512254b5a7450fed912f340da16065c1e65d626dbe8d1
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 RAPGEF4 SULT1B1 AFAP1 SPHK1

1.64e-041871225e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

SPEG APBB2 DGKB PRKD1 CNN3

1.64e-041871225464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 CHD3 GRIK4 GRIN2A GRIN2B

1.64e-041871225e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 CHD3 GRIK4 GRIN2A GRIN2B

1.64e-04187122524cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN2 CHD3 GRIK4 GRIN2A GRIN2B

1.64e-0418712252f153b203fe79f206319603cf94d3a03ab49a05d
ToppCelldroplet-Spleen-SPLEEN-1m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCT3 SIPA1 CORO1A FMNL1 CNN3

1.69e-041881225713fbbd55d2853dee3df2336cada32c153cbd2a1
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF4 SIPA1 BLK CORO1A CNN3

1.69e-0418812258b1485e63cd4020ba5334a8d4b84725b164549bf
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTS19 ITSN1 RTTN AGPAT4 GRIN2A

1.69e-041881225b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellNeuronal_cells-Schwann_cells|World / Lineage and Cell class

PAK5 APBB1 FSD1 PIGZ SLC12A2

1.73e-041891225371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCellNeuronal_cells|World / Lineage and Cell class

PAK5 APBB1 FSD1 PIGZ SLC12A2

1.73e-0418912253948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RAPGEF4 APBB2 HSPA12B SHPK PRKD1

1.73e-041891225bccb3481ffed597c845fe860da658505316105b5
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TOX PAK5 HSPA12B TRIM47 CNN3

1.73e-041891225360f09f46231a83f99d8fa0158b72a38068e1642
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAPGEF4 DGKE HSPA12B SULT1B1 EPHA4

1.77e-041901225bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SPTBN2 DPYSL5 GRIN2A GRIN2B KMT2A

1.77e-041901225416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TOX SPTBN2 EML6 GRIN2B ARL6IP1

1.77e-041901225078f4be52fa4cc8dd9c8d7a2b6d9631c3d902285
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK TOX MCCC1 DUOX1 PRKD1

1.81e-041911225a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

FAT4 RAPGEF4 GRIN2A HSPA12B SLC12A2

1.81e-041911225f229abf69a1217194f74b0502486907e07dba989
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TOX PAK5 APBB2 HSPA12B TRIM47

1.81e-041911225d162917816dd2e4767c97447c1cddae9397713ab
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF4 SIPA1 BLK CORO1A CNN3

1.86e-0419212259b8191e66626919cad2c63349c8ef61e9792fcf5
ToppCellNS-moderate-d_16-33-Lymphoid-Treg|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TOX BLK STK4 CORO1A FMNL1

1.86e-04192122548d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK TOX MCCC1 DUOX1 PRKD1

1.90e-041931225fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIL1 EML6 PIGZ CLCA1 SLC12A2

1.90e-041931225402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIL1 EML6 PIGZ CLCA1 SLC12A2

1.90e-0419312257ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCellIPF-Lymphoid|IPF / Disease state, Lineage and Cell class

TOX CORO1B BLK STK4 CORO1A

1.90e-041931225bf9d50aea909a28dd1d0933af33842d5f1ae7818
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TNIK TOX MCCC1 DUOX1 PRKD1

1.90e-041931225f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellDendritic_Cells|World / lung cells shred on cell class, cell subclass, sample id

F13A1 CORO1A ADAMDEC1 PAK1 FMNL1

1.90e-0419312257792eb6e247af2d7a8f80476f37dcd880922d625
ToppCell10x5'v1-week_12-13-Lymphocytic_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TOX APBB1 FSD1 GRIK4 EPHA4

1.95e-0419412255afe7f48d3383f3dac18765f97999c8b6936dc1b
ToppCellRV-09._Endothelium_I|RV / Chamber and Cluster_Paper

APBB2 DGKE HSPA12B PRKD1 EPHA4

1.95e-0419412257b408096e717f2327c12aea35a8d5fc4621d3b06
ToppCell10x5'v1-week_12-13-Lymphocytic_NK-T_NK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TOX APBB1 FSD1 GRIK4 EPHA4

1.95e-041941225ec7e0ca6c9a2f63938e06ee771da09eff14fc3b5
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 RAPGEF4 APBB2 GRIK4 STK4

1.95e-0419412250b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

TNIK TOX MCCC1 DUOX1 PRKD1

1.95e-04194122597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TOX FSD1 BLK CORO1A EPHA1

2.00e-041951225caa3669739974b63470f7e557df96e8d3844dd84
ToppCellBAL-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

F13A1 SPHK1 PAK1 KCNN1 CCNA1

2.00e-04195122566e5fd9f3208a06d617c5e994822bf57dceae7e2
ToppCellBAL-Severe-Lymphocyte-T/NK-CD8+_T-MAIT-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TOX FSD1 BLK CORO1A EPHA1

2.00e-041951225bc5728e9df0b15adec50a7c840ce9f2775135087
ToppCellBAL-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

F13A1 SPHK1 PAK1 KCNN1 CCNA1

2.00e-0419512259e5cf33b5dd455efa464a63d7116786c0786aefd
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

F13A1 BLK STK4 CORO1A FMNL1

2.00e-0419512257b6c69df943842b566a596e30bb50dbe80dccc83
ToppCellMacrophages-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

GRIN2A SULT1B1 SH3GLB1 ARL6IP1 UBE2V1

2.00e-041951225e48bf57e6da23fbb4637a02387155f825455c49f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAK5 EML6 RAPGEF4 GRIN2A GRIN2B

2.05e-041961225676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellAdult-Immune-monocyte-D122|Adult / Lineage, Cell type, age group and donor

F13A1 CORO1A EHBP1L1 IL17RA FMNL1

2.05e-04196122516b0acb6157534938ca83d4e909471e33a7d3c52
ToppCellTransplant_Alveoli_and_parenchyma-Immune-Dendritic_cells|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

F13A1 STK4 CORO1A PAK1 FMNL1

2.05e-041961225f278b144b8deaee0bf41682081b9fbb0b1e82b19
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Neuronal-CPNs|6_mon / Sample Type, Dataset, Time_group, and Cell type.

PAK5 GRIA4 GRIN2B CORO1A EPHA4

2.05e-041961225c9e7ac34993c873de4f198cdae77dcf099731532
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TNIK DGKE CHD3 KMT2A TNNI1

2.09e-04197122557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellControl-B_memory-3|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TOX BLK TLE3 TRIM47 EPHA4

2.09e-041971225b86385c6c1d52ef4e3d855004d77afab61556978
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

F13A1 CORO1A EHBP1L1 ADAMDEC1 FMNL1

2.09e-041971225515a2d0ee2bd3fc0a5a0c315e2b0c752e6af7406
ToppCell(1)_T_cell-(15)_Treg|(1)_T_cell / shred on Cell_type and subtype

TNIK TOX GCK CORO1B TLR5

2.09e-0419712256e7723e8b977be35c60cc11ac7cfa4f71339441e
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

F13A1 CORO1A EHBP1L1 ADAMDEC1 FMNL1

2.09e-041971225bfa04e5f4156a01df4217b1f59676edb0a7563e1
ToppCell5'-Airway_Nasal-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

F13A1 CORO1A EHBP1L1 ADAMDEC1 FMNL1

2.09e-0419712254fccdc69ab4b966de6465f06677435e6f6e6abcd
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

F13A1 BLK STK4 CORO1A FMNL1

2.09e-04197122561ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

TNIK FAT4 GRIK4 PRKD1 VPS13B

2.09e-041971225f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCelldistal-Hematologic-Myeloid_Dendritic_Type_2-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

F13A1 CORO1A OXA1L PAK1 FMNL1

2.14e-041981225984b3753fabd5553f6f364f90a422b035e421535
DrugNorethindrone [68-22-4]; Down 200; 13.4uM; PC3; HT_HG-U133A

ZNF609 MED16 APBB2 PTPN21 RAD54L2 STK3 STK4 CORO1A AFAP1 TMEM259 ENTPD5

9.35e-09197122115055_DN
DrugYM90K

GRIA4 GRIK4 GRIN2A GRIN2B CABIN1

1.27e-07231225CID005486547
Druggavestinel

GRIA4 GRIK4 GRIN2A GRIN2B PRKD1

1.98e-07251225CID006450546
DrugKN-62

GRIA4 GRIK4 GRIN2A GRIN2B CLCA1 SPHK1 PAK1 PRKD1 CABIN1 CREB3L2

4.67e-0723012210CID000003838
DrugCisapride [81098-60-4]; Down 200; 8.6uM; PC3; HT_HG-U133A

TNIK VWA8 SPTBN2 IREB2 PTPN21 MAPK8IP3 STK4 CORO1A TMEM259

1.09e-0619512296706_DN
DrugDenatonium benzoate [3734-33-6]; Down 200; 9uM; PC3; HT_HG-U133A

TNIK FAT4 SPEG MINK1 STK4 CORO1A AFAP1 CLCN4 EPHA1

1.14e-0619612295061_DN
DrugViomycin sulfate [37883-00-4]; Up 200; 5.2uM; MCF7; HT_HG-U133A

ZNF609 MINK1 APBB2 PTPN21 SIPA1 ENTPD5 SLC38A7 KMT2A IL17RA

1.19e-0619712297036_UP
Drugestradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A

MINK1 MAPK8IP3 SULT1B1 CLCN4 ENTPD5 PAK1 TRPM8 VPS13B EPHA1

1.24e-0619812296200_UP
DrugProxyphylline [603-00-9]; Down 200; 16.8uM; HL60; HT_HG-U133A

TNIK MED16 MINK1 PAK4 TFIP11 CHD3 EHBP1L1 TLE3 KMT2A

1.29e-0619912293115_DN
DrugGAMs

GRIA4 GRIK4 GRIN2A GRIN2B PRKD1

1.77e-06381225CID000002935
DrugIDRA 21

GRIA4 GRIK4 GRIN2A GRIN2B

3.56e-06201224CID000003688
DrugCX546

GRIA4 GRIK4 GRIN2A GRIN2B

4.38e-06211224CID000002890
Drugtetrahydrozoline

ABCC6 NUTM1 SLC12A2

5.17e-0671223CID000005419
DrugNS 102

GRIA4 GRIK4 GRIN2A GRIN2B

5.33e-06221224CID005282252
DrugCX516

GRIA4 GRIK4 GRIN2A GRIN2B

5.33e-06221224CID000148184
DrugAC1L1B1W

TNPO1 GRIA4 GRIK4 GRIN2A GRIN2B SLC12A2

6.04e-06841226CID000001248
DrugL-CCG-I

TNPO1 GRIA4 GRIK4 GRIN2A GRIN2B

7.11e-06501225CID000001271
Drugmagnesium

TNPO1 MAN2B2 NTHL1 PAK4 DPYSL5 DGKB GRIA4 DGKE GRIK4 GCK GRIN2A GRIN2B MCCC1 ARL1 GUCY2C SPHK1 ENTPD6 ENTPD5 PRKD1 TNNI1 CABIN1

7.14e-06132512221CID000000888
DrugCGP 39653

GRIA4 GRIK4 GRIN2A GRIN2B

7.67e-06241224CID006437837
DrugLY354740

TNPO1 GRIA4 GRIK4 GRIN2A GRIN2B

7.85e-06511225CID000114827
Drugperzinfotel

GRIK4 GRIN2A GRIN2B

8.24e-0681223CID006918236
Drugi 143

PAK4 PAK1 PAK2

8.24e-0681223CID002777991
DrugApramycin [37321-09-8]; Down 200; 7.4uM; PC3; HT_HG-U133A

MED16 SPTBN2 APBB2 MAPK8IP3 STK4 CLCN4 CABIN1 EPHA1

1.05e-0519512286614_DN
DrugFlucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; PC3; HT_HG-U133A

ZNF609 SPTBN2 PTPN21 STK3 AFAP1 CLCN4 KCNN1 EPHA4

1.09e-0519612285102_DN
DrugFlutamide [13311-84-7]; Down 200; 14.4uM; PC3; HT_HG-U133A

TOX SPEG APBB2 FSD1 PTPN21 MAPK8IP3 CORO1A EPHA4

1.09e-0519612284539_DN
DrugFlurbiprofen [5104-49-4]; Down 200; 16.4uM; HL60; HT_HG-U133A

ZNF609 ANGEL1 APBB2 MAPK8IP3 CLCN4 PAK1 KMT2A VPS13B

1.09e-0519612283095_DN
DrugHomatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT_HG-U133A

ANGEL1 CHD4 EHBP1L1 AFAP1 CLCN4 TLE3 KMT2A IL17RA

1.13e-0519712281806_DN
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

ZNF609 APBB2 FSD1 STK4 TLE3 ENTPD5 KMT2A IL17RA

1.13e-0519712284476_DN
DrugKynurenine, 3-hydroxy (R,S) [2147-61-7]; Up 200; 17.8uM; MCF7; HT_HG-U133A

MED16 SPEG MINK1 APBB2 SIPA1 STK3 DUOX1 VPS13B

1.13e-0519712282654_UP
DrugOndansetron Hydrochloride [103639-04-9]; Down 200; 12.2uM; MCF7; HT_HG-U133A

MED16 APBB2 IREB2 DGKE PTPN21 RAD54L2 AFAP1 TMEM259

1.13e-0519712283575_DN
DrugSparteine (-) [90-39-1]; Down 200; 17uM; PC3; HT_HG-U133A

TNIK ZNF609 IREB2 PTPN21 CLCN4 TLE3 ENTPD5 EPHA4

1.17e-0519812284568_DN
DrugHydrocotarnine hydrobromide [5985-00-2]; Down 200; 13.2uM; MCF7; HT_HG-U133A

VWA8 MINK1 DGKE CHD3 PTPN21 CORO1A ARL1 TLR5

1.17e-0519812286827_DN
DrugButacaine [149-16-6]; Down 200; 13uM; PC3; HT_HG-U133A

FSD1 PIGZ MAPK8IP3 AFAP1 TMEM259 ENTPD5 PRKD1 CABIN1

1.22e-0519912285748_DN
DrugChlorphensin carbamate [886-74-8]; Up 200; 16.2uM; PC3; HT_HG-U133A

ZNF609 SPTBN2 AGPAT4 MAPK8IP3 STK4 ENTPD5 KCNN1 KMT2A

1.22e-0519912282115_UP
DrugNS3763

GRIK4 GRIN2A GRIN2B

1.23e-0591223CID004359312
DrugL-689,560

GRIA4 GRIK4 GRIN2A GRIN2B

1.25e-05271224CID000121918
DrugCarbarsone [121-59-5]; Down 200; 15.4uM; PC3; HT_HG-U133A

ZNF609 MED16 SPEG APBB2 MAPK8IP3 SLC38A7 IL17RA CABIN1

1.26e-0520012283991_DN
DrugBenzonatate [104-31-4]; Down 200; 6.6uM; PC3; HT_HG-U133A

SPEG DUS4L APBB2 IREB2 MAPK8IP3 FAIM IL17RA CABIN1

1.26e-0520012286334_DN
DrugC-PP

GRIA4 GRIK4 GRIN2A GRIN2B

1.45e-05281224CID000001228
Drugaptiganel

GRIA4 GRIK4 GRIN2A GRIN2B

1.45e-05281224CID000060839
Drugglutamate

TNPO1 HYOU1 SPTBN2 AGPAT4 IREB2 GRIA4 GRIK4 GCK GRIN2A GRIN2B MCCC1 CLCA1 CLCN4 ARL6IP1 TRPM8 PRKD1 CABIN1

1.50e-0596212217CID000000611
Drugbiotinyl-L-lysine

TNPO1 GRIA4 GRIN2A GRIN2B MCCC1 SPAG5

1.56e-05991226CID000083814
DrugMPEP

TNPO1 GRIA4 GRIK4 GRIN2A GRIN2B

1.62e-05591225CID003025961
DrugAC1NUW3V

GRIA4 GRIK4 GRIN2A GRIN2B

1.68e-05291224CID005462126
Drugketobemidone

GRIA4 GRIK4 GRIN2A GRIN2B

1.68e-05291224CID000010101
Drugnylidrin

GRIN2A GRIN2B EPHA1

1.75e-05101223CID000004567
Drug3,5-dihydroxyphenylglycine

GRIA4 GRIK4 GRIN2A GRIN2B CREB3L2

1.76e-05601225CID000108001
Drugcis-2,3-piperidine dicarboxylic acid

GRIA4 GRIK4 GRIN2A GRIN2B

1.93e-05301224CID000001226
DrugLY293558

GRIA4 GRIK4 GRIN2A GRIN2B

1.93e-05301224CID000127894
DrugGYKI 53655

GRIA4 GRIK4 GRIN2A GRIN2B

1.93e-05301224CID000126757
DrugAC1L32TU

GRIA4 GRIK4 GRIN2A GRIN2B

1.93e-05301224CID000107831
DrugNPC 12626

GRIA4 GRIK4 GRIN2A GRIN2B

2.21e-05311224CID000108099
Drug4-methylglutamic acid

GRIA4 GRIK4 GRIN2A GRIN2B

2.21e-05311224CID000005365
DrugLY235959

GRIA4 GRIK4 GRIN2A GRIN2B

2.21e-05311224CID000131938
Drugeliprodil

GRIA4 GRIK4 GRIN2A GRIN2B

2.21e-05311224CID000060703
Drugtrans-3,4,5-trihydroxystilbene

GRIA4 GRIK4 GRIN2A GRIN2B SULT1B1 OXA1L GUCY2C SPHK1 CCNA1 PRKD1 IL17RA CABIN1 EPHA4

2.37e-0560812213CID000005056
Drugalpha-methyl-4-carboxyphenylglycine

GRIA4 GRIK4 GRIN2A GRIN2B

2.51e-05321224CID000001222
Drug1-aminoindan-1,5-dicarboxylic acid

GRIA4 GRIK4 GRIN2A GRIN2B

2.85e-05331224CID000002071
Drug6,7-dinitroquinoxaline

GRIA4 GRIK4 GRIN2A GRIN2B

2.85e-05331224CID002724608
DrugD-CPPene

GRIA4 GRIK4 GRIN2A GRIN2B

3.21e-05341224CID006435801
Drugkainite

GRIA4 GRIK4 GRIN2A GRIN2B

3.61e-05351224CID000164810
DrugNSC618487

TNIK SEC16B HYOU1 PAK5 PAK4 APBB2 DGKB DGKE GRIN2A GRIN2B STK4 DUOX1 SPHK1 PRKD1 CABIN1 EPHA4

3.91e-0593312216CID000005279
DrugR,S)-AMPA

GRIA4 GRIK4 GRIN2A GRIN2B

4.05e-05361224CID000001221
DrugC6H12NO5P

GRIA4 GRIK4 GRIN2A GRIN2B

4.05e-05361224CID000104962
Druggacyclidine

GRIA4 GRIK4 GRIN2A GRIN2B

4.05e-05361224CID000176265
Drugglutamic acid diethyl ester

GRIA4 GRIK4 GRIN2A GRIN2B

4.05e-05361224CID000073960
Druggamma-Glu-Gly

GRIA4 GRIK4 GRIN2A GRIN2B

4.52e-05371224CID000100099
DrugNivalenol hydrate

GRIN2B TRIM47 EPHA1 EPHA4

5.03e-05381224CID000031829
DrugL-BMAA

GRIA4 GRIK4 GRIN2A GRIN2B

5.03e-05381224CID000028558
DrugCGS 19755

GRIA4 GRIK4 GRIN2A GRIN2B

5.03e-05381224CID000068736
Drug4CPG

GRIA4 GRIK4 GRIN2A GRIN2B

5.03e-05381224CID000005115
Drugibotenic acid

GRIA4 GRIK4 GRIN2A GRIN2B CLCA1 CLCN4

5.09e-051221226CID000001233
Drugkynurenic acid

GRIA4 GRIK4 GRIN2A GRIN2B SULT1B1 UBE2V1

5.09e-051221226CID000003845
DrugMethamphetamine

TNPO1 MAGEA4 SLK ZNF609 NTHL1 SPEG ANGEL1 DPYSL5 CHD4 GRIN2A GRIN2B HSPA12B ABCC6 MAPK8IP3 EHBP1L1 TMEM259 TLE3 CCNA1 TNNI1 CABIN1

5.39e-05140112220ctd:D008694
Drug2-amino-3-phosphonopropionic acid

GRIA4 GRIK4 GRIN2A GRIN2B PRKD1

5.55e-05761225CID000003857
DrugHA-966

GRIA4 GRIK4 GRIN2A GRIN2B

5.58e-05391224CID000001232
DrugDETC-MeSO

GRIA4 GRIK4 GRIN2A GRIN2B

5.58e-05391224CID003035711
Drugginsenoside Rg3

GRIN2A GRIN2B BLK TLE3

6.18e-05401224CID000159727
DrugACEA-1011

GRIK4 GRIN2A GRIN2B

6.52e-05151223CID000127872
Drugthiokynurenic acid

GRIA4 GRIN2A GRIN2B

6.52e-05151223CID003035667
Drug4-AP

GRIA4 GRIK4 GRIN2A GRIN2B HSPA12B GUCY2C KCNN1 PRKD1

7.72e-052581228CID000001727
DrugLuteolin [491-70-3]; Down 200; 14uM; PC3; HT_HG-U133A

ZNF609 ITSN1 MAPK8IP3 STK4 CLCN4 SPHK1 EPHA4

7.78e-0519112276658_DN
Drugargiopine

GRIK4 GRIN2A GRIN2B

7.99e-05161223CID000122294
DrugLY233536

GRIA4 GRIN2A GRIN2B

7.99e-05161223CID000126239
DrugRisperidone [106266-06-2]; Down 200; 9.8uM; HL60; HT_HG-U133A

DUS4L PAK4 APBB2 TFIP11 EHBP1L1 TLE3 EPHA4

8.04e-0519212272947_DN
DrugAstemizole [68844-77-9]; Down 200; 8.8uM; HL60; HG-U133A

ZNF609 MED16 NTHL1 MINK1 F13A1 KMT2A CABIN1

8.04e-0519212271365_DN
DrugMethionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT_HG-U133A

TNIK SPEG MINK1 F13A1 MAPK8IP3 BLK SHPK

8.04e-0519212274151_UP
DrugHomatropine hydrobromide (R,S) [51-56-9]; Down 200; 11.2uM; PC3; HT_HG-U133A

MED16 APBB2 CHD3 PTPN21 STK4 TMEM259 KMT2A

8.04e-0519212275058_DN
DrugLY341495

GRIA4 GRIK4 GRIN2A GRIN2B

8.24e-05431224CID006324636
DrugJoro spider toxin

GRIA4 GRIK4 GRIN2A GRIN2B

8.24e-05431224CID000119582
DrugEnilconazole [35554-44-0]; Down 200; 13.4uM; HL60; HT_HG-U133A

ZNF609 PAK4 APBB2 STK3 SHPK VPS13B EPHA4

8.31e-0519312273139_DN
DrugPyrantel tartrate [33401-94-4]; Down 200; 11.2uM; PC3; HT_HG-U133A

TNIK STK4 CLCN4 TMEM259 KCNN1 CABIN1 EPHA4

8.31e-0519312275088_DN
DrugButylparaben [94-26-8]; Down 200; 20.6uM; MCF7; HT_HG-U133A

ZNF609 MINK1 APBB2 RAD54L2 SULT1B1 EHBP1L1 CABIN1

8.31e-0519312275608_DN
Drugphorbol 12-myristate

SEC16B SIPA1 GRK1 EHBP1L1 CLCN4 SPHK1 PRKD1 CABIN1

8.37e-052611228CID000107854
Drugconotoxin GV

GRIN2A GRIN2B

8.51e-0531222ctd:C055407
DrugFelbamate

GRIN2A GRIN2B

8.51e-0531222DB00949
DrugRp-cAMPS

RAPGEF4 GRIA4 GRIK4 GRIN2A GRIN2B GUCY2C PRKD1

8.58e-051941227CID006426631
Drug0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A

MED16 TFIP11 PTPN21 RAD54L2 SULT1B1 TMEM259 SLC38A7

8.58e-0519412274331_DN
DrugPhenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A

ZNF609 AGPAT4 MAPK8IP3 CORO1A CLCA1 ENTPD5 PRKD1

8.58e-0519412273725_DN
Drug(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A

ZNF609 MED16 STK4 TMEM259 ENTPD5 KMT2A EPHA4

8.58e-0519412274524_DN
Diseaseobesity (implicated_via_orthology)

SEC16B FAT4 GCK STK3 STK4 GUCY2C SPHK1

3.09e-052151217DOID:9970 (implicated_via_orthology)
DiseaseNF-kappa-B essential modulator measurement

STK3 VPS13B

4.99e-0531212EFO_0010597
Diseaseepisodic memory

TNPO1 EML6 GRIN2A CORO1A

6.26e-05521214EFO_0004333
DiseaseMetastatic melanoma

PAK5 GUCY2C PRKD1 EPHA4

7.26e-05541214C0278883
Diseaseinformation processing speed, response to cranial radiation therapy

SEC16B PAK5 GRIA4 HSPA12B

9.62e-05581214EFO_0004363, EFO_0010950
Diseasecarcinoma (implicated_via_orthology)

FAT4 BLK STK3 STK4

1.41e-04641214DOID:305 (implicated_via_orthology)
Diseaseglucose metabolism disease (implicated_via_orthology)

DGKB GCK TLR5

2.04e-04281213DOID:4194 (implicated_via_orthology)
Diseaseentorhinal cortical volume

F13A1 EPHA4

2.47e-0461212EFO_0005092
Diseaseschizophrenia (is_implicated_in)

GRIA4 GRIN2A GRIN2B PAK1

3.04e-04781214DOID:5419 (is_implicated_in)
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN2A GRIN2B

4.59e-0481212DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN2A GRIN2B

4.59e-0481212DOID:1561 (biomarker_via_orthology)
Diseaselevel of Triacylglycerol (53:4) in blood serum

TOX BUD13

4.59e-0481212OBA_2045166
Diseaseepilepsy (implicated_via_orthology)

TNIK MINK1 GRIN2A GRIN2B SLC12A2

5.74e-041631215DOID:1826 (implicated_via_orthology)
Diseasecomplement factor D measurement

ZNF609 MED16 RTTN DISP3

5.93e-04931214EFO_0020283
Diseasesuicide behaviour measurement

PTPN21 SLC38A7 ZCCHC7

7.36e-04431213EFO_0006882
Diseasesexual dysfunction

ADAMTS19 PRKD1

8.95e-04111212EFO_0004714
Diseasehyperhomocysteinemia (implicated_via_orthology)

GRIN2A GRIN2B

8.95e-04111212DOID:9279 (implicated_via_orthology)
Diseasevascular dementia (is_marker_for)

GRIN2A GRIN2B

8.95e-04111212DOID:8725 (is_marker_for)
Diseasequality of life during menstruation measurement, dysmenorrheic pain measurement

GRIN2A VPS13B

8.95e-04111212EFO_0007889, EFO_0009366
DiseaseSchizophrenia

TNIK SPTBN2 GRIA4 CHD4 GRIK4 GRIN2A GRIN2B PTPN21 SLC12A2 PAK2 KMT2A

1.04e-0388312111C0036341
Diseasecoronary artery disease

FAT4 SLK DUS4L BUD13 GRIK4 SIPA1 F13A1 MAPK8IP3 STK3 EHBP1L1 RPTOR KCTD10 CABIN1

1.26e-03119412113EFO_0001645
Diseasemetabolic syndrome

SEC16B BUD13 GCK SIPA1 KMT2A

1.43e-032001215EFO_0000195
DiseaseMaturity onset diabetes mellitus in young

GCK BLK

1.47e-03141212C0342276
Diseaseunipolar depression, response to escitalopram, response to citalopram, mood disorder

CORO1B TLE3

1.69e-03151212EFO_0003761, EFO_0004247, EFO_0006329, EFO_0007871
Diseasemelanoma

SLK HMCN2 UQCC1 TRPM8

1.83e-031261214EFO_0000756
DiseaseMonogenic diabetes

GCK BLK

1.93e-03161212C3888631
Diseasebrain measurement, neuroimaging measurement

TNIK ADAMTS19 DPYSL5 CORO1A AFAP1 ENTPD6 SLC38A7 EPHA4

1.98e-035501218EFO_0004346, EFO_0004464
Diseasechylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

AGPAT4 BUD13 TP53BP1

2.04e-03611213EFO_0008317, EFO_0008596, EFO_0020946
DiseaseAlzheimer's disease (is_implicated_in)

APBB1 APBB2 IREB2 GRIN2B

2.17e-031321214DOID:10652 (is_implicated_in)
Diseasefish consumption measurement

TOX DGKB SLC38A7

2.34e-03641213EFO_0010139
Diseasetotal blood protein measurement

ZNF609 HYOU1 DGKE HSPA12B BLK EHBP1L1 TLE3

2.57e-034491217EFO_0004536
Diseaseopioid dependence

FAT4 SPTBN2 GRIN2B F13A1 NWD2

2.99e-032371215EFO_0005611
Diseaseneurodegenerative disease (implicated_via_orthology)

FAT4 GRIA4 STK3 STK4

3.05e-031451214DOID:1289 (implicated_via_orthology)
Diseaserosacea severity measurement

DGKB GRIN2A STK3 EHBP1L1

3.20e-031471214EFO_0009180
Diseaseobsolete_red blood cell distribution width

TNPO1 TRIM15 CCT3 ITSN1 BUD13 CHD4 SIPA1 EHBP1L1 SLC12A2 TMEM259 SPHK1 KCTD10 PAK2

3.59e-03134712113EFO_0005192
Diseasesleep duration

TNIK MINK1 BUD13 F13A1 KMT2A ZCCHC7

3.86e-033621216EFO_0005271
DiseaseHuntington's disease (is_implicated_in)

GRIN2A GRIN2B

3.99e-03231212DOID:12858 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
LLQGMEAADWTGIGV

nan

16

A8MU10
PAWLMVDTVIGEGEF

EPHA1

621

P21709
FSGRMEVLTDSEGWI

KCTD10

61

Q9H3F6
GKGMRIVDDDVSWTA

BUD13

46

Q9BRD0
WEMGAVEAISLSILV

DISP3

1231

Q9P2K9
DIRDTVGIWGEGKDM

APBB2

456

Q92870
LEASSSEDMGRWIGI

AFAP1

421

Q8N556
SEDMGRWIGILLAET

AFAP1

426

Q8N556
EMTISAIDGGWVART

FAT4

3161

Q6V0I7
EVIASGSEDCTVMVW

CORO1B

96

Q9BR76
TASLEEQLQGWGEVM

ARL6IP1

16

Q15041
AVRSLGWVEMTEEEL

APBB1

371

O00213
TKGTGLDEAMEWLVE

ARL1

161

P40616
AGTLAGVIDLAVDWM

CLCN4

81

P51793
VIASGSEDCTVMVWE

CORO1A

96

P31146
RAKVMADWVSEGGVL

RAD54L2

386

Q9Y4B4
MVVWVTGASSGIGEE

DHRS7

51

Q9Y394
GVLSIWDIDIITAMS

NWD2

1296

Q9ULI1
LVPGAEEVTMVTWEE

QRICH2

41

Q9H0J4
NWGEDMTSVDAAILI

ADAMTS19

421

Q8TE59
PVTLDDWGDVDSTMV

GUCY2C

366

P25092
ILGWGVGGIETEAVM

IREB2

291

P48200
VMLVKVGEGEEGQWS

GCK

86

P35557
VSEKLVGGMEALEWQ

DUOX1

636

Q9NRD9
GTEVDIWSLGIMVIE

PAK5

621

Q9P286
EEQAISEAGVMTWVG

IL17RA

416

Q96F46
TSGVGADVARMWEIA

PRKD1

521

Q15139
IMDGSDEGILAWVTV

ENTPD5

166

O75356
SASEEEIWEELGVMG

MAGEA4

216

P43358
GMGSSDEWSDVQDII

MAPK8IP3

331

Q9UPT6
LSVEWDAMGGKVQDI

FSD1

286

Q9BTV5
TIWGSNETGEVAVME

HMCN2

1531

Q8NDA2
FGIVVMVTETELSWG

KCNN1

116

Q92952
IASPLEGGWEEVSIM

EPHA4

46

P54764
DADTKIWNGMVGELV

GRIA4

476

P48058
VQMDDWKIVSGGEEG

FBXW8

481

Q8N3Y1
VLRVQEAEAGVWGMS

EHBP1L1

931

Q8N3D4
MVNAKDDEGVLVGSW

F13A1

266

P00488
ATMWAVLELGAETGV

OXA1L

271

Q15070
TFLVESGVGELWAEM

HSPA12B

296

Q96MM6
MEGWIAVTVSGLVTV

MED16

176

Q9Y2X0
GVWLSSEMDAVGLEL

NUTM1

721

Q86Y26
WEQGIAIIAMVTAEE

PTPN21

986

Q16825
DIWSLGIMAIEMIEG

PAK1

446

Q13153
IWSLGIMAIEMVEGE

PAK2

426

Q13177
WLEDEGVGATTVMLK

HYOU1

781

Q9Y4L1
EEWVATVTQLLMGIE

CABIN1

781

Q9Y6J0
WAQGTDTILADEMGL

CHD3

751

Q12873
ADVWSFGVLLMEVVT

BLK

416

P51451
IVMVKGEWVDESQTG

ITSN1

766

Q15811
EGMRTILVDWLVEVG

CCNA1

241

P78396
MTDLVAVWDVALSDG

FAIM

1

Q9NVQ4
DGTVSLEEWIQGGMT

DGKB

211

Q9Y6T7
VTEMITGTDLVEWQL

MCCC1

346

Q96RQ3
AWEAVEMEIVAGQLV

MAN2B2

646

Q9Y2E5
GDLGWMAETAAIITD

TMEM259

536

Q4ZIN3
VDTGGVSRKVAADWM

FMNL1

91

O95466
GIEVNLLGSMESESW

KANK4

431

Q5T7N3
AENVWEMGGLGILTS

KMT2A

1411

Q03164
ENVWRITGTDGVMVA

DUS4L

226

O95620
LIDGHMEGEIWGLAT

EML6

1681

Q6ZMW3
GTVGWVLDAVDDMKI

DGKE

281

P52429
VEAGIMTATTWLKEG

ERCC6L2

716

Q5T890
TWTGMVGELIARKAD

GRIK4

481

Q16099
EMIETGIFGELNVWR

GRK1

521

Q15835
WAQGTDTILADEMGL

CHD4

741

Q14839
MLVSGLAGEKARWEE

DNAH2

3281

Q9P225
MEVLESGEQGVLQWD

CREB3L2

1

Q70SY1
SVIWERGVVGGKMDE

DPYSL5

356

Q9BPU6
LVGDELWVVMEFLEG

PAK4

386

O96013
IWSLGITAIEMAEGA

MINK1

216

Q8N4C8
EDMTLIGEAISTDIW

RTTN

411

Q86VV8
TQAVGMWQVLLEDGV

RAPGEF4

256

Q8WZA2
VEIIEGWVSMGVMAE

TRIM47

486

Q96LD4
EDVGRILGSDTESWM

SPAG5

326

Q96R06
ADVWSLGITLIEMAE

SLK

216

Q9H2G2
IGKIIGGMWRDLTDE

SMARCE1

96

Q969G3
VSIMNGTDEGVSAWI

ENTPD6

216

O75354
DWIIVLANGAIAEMG

ABCC6

821

O95255
MAVAWGTVSGIAVDT

NTHL1

226

P78549
VITVFSVVGMDSDWL

SH3GLB1

331

Q9Y371
QWMADLGLEVEESTV

SHPK

336

Q9UHJ6
IMSEAGSGTLEDEWQ

SIPA1

916

Q96FS4
WGGVVTAAMVIALAV

SLC38A7

276

Q9NVC3
ETWGVNGETGTLVDM

CCT3

476

P49368
TTWVSEIIDMILNDG

SULT1B1

51

O43704
TTRGAGMVVDWEQET

RPTOR

1121

Q8N122
GMVVDWEQETGLLMS

RPTOR

1126

Q8N122
WEQETGLLMSSGDVR

RPTOR

1131

Q8N122
SLAQMLDEDTVVGVW

ABTB1

371

Q969K4
VQVALVGMEIWSDGD

ADAMDEC1

261

O15204
LLEVEGVEGSMWAAI

ANGEL1

136

Q9UNK9
QTVELGSWVGMVTFD

CLCA1

336

A8K7I4
DLRNWIEEVTGMSIG

CNN3

31

Q15417
GEKVLLTGSVMGTEW

TRIML2

336

Q8N7C3
KMVDDGSGEVQVWRI

VIL1

391

P09327
VADIWSLGITSIEMA

STK3

201

Q13188
LWSLGITAIEMAEGA

TNIK

216

Q9UKE5
TMLSEAGACGLWVEE

SPTBN2

856

O15020
EMVKGEPIGSATDIW

SPEG

3131

Q15772
DDVVVMATDGLWDVL

PPM1M

376

Q96MI6
EVVALVEGVTWMSEE

ZNF274

231

Q96GC6
VEGVTWMSEEEVLPA

ZNF274

236

Q96GC6
TVVILLGISVAGMEW

SLC12A2

416

P55011
GEMGLSAEDGVWAVI

TRIM15

376

Q9C019
GIVWQETEDGMLVVN

ZNF609

316

O15014
GTVSWGLEDDEDMTL

UBE2V1

31

Q13404
VEVGDWRKNVEAMSG

TNNI1

156

P19237
ELWSEILMTGGAASV

TP53BP1

1886

Q12888
EGFEDVVTTWRTVMG

NME9

236

Q86XW9
SMNGEDLLLTGEVSW

UQCC1

261

Q9NVA1
GEVVEEALDVCEMWG

nan

151

A6NLC8
PVEVVDMGGTEDWAL

PIGZ

481

Q86VD9
ATWAIGEISIQMGIE

TNPO1

736

Q92973
TEATGGTVWEEMLQT

SEC16B

816

Q96JE7
GEWLAVGMESSNVEV

TLE3

671

Q04726
WEQEGTTVEALMMGE

VPS13B

426

Q7Z7G8
TISEGDNVESWMLLG

ZCCHC7

166

Q8N3Z6
DIWSLGITAIEMAEG

STK4

206

Q13043
SEELGRWDALVVMSG

SPHK1

66

Q9NYA1
GVRWMIGVTEIDKGS

AGPAT4

351

Q9NRZ5
EENIVAIGIAAWGMV

TRPM8

206

Q7Z2W7
MVLEILDVSGNGWTV

TLR5

226

O60602
LAEWDKSGVVTVDMG

VWA8

1491

A3KMH1
VSKIVASMWDGLGEE

TOX

291

O94900
WEGMISVSSLVGLLE

TFIP11

641

Q9UBB9
GEMEELETLWLTGIC

GRIN2A

786

Q12879
DGEMEELEALWLTGI

GRIN2B

786

Q13224