Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K9me2/H3K9me3 demethylase activity

KDM4C KDM4E KDM4D KDM4B

1.12e-0861064GO:0140684
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

KDM4C KDM4E KDM4D KDM4B

7.21e-07141064GO:0032454
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM4C KDM4E KDM4D KDM4B

1.39e-05281064GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM4C KDM4E KDM4D KDM4B

2.11e-05311064GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM4C KDM4E KDM4D KDM4B

2.41e-05321064GO:0140457
GeneOntologyMolecularFunctionacyl-L-homoserine-lactone lactonohydrolase activity

PON1 PON2

8.35e-0531062GO:0102007
GeneOntologyMolecularFunctionlactonohydrolase activity

PON1 PON2

8.35e-0531062GO:0046573
GeneOntologyMolecularFunctiondemethylase activity

KDM4C KDM4E KDM4D KDM4B

8.65e-05441064GO:0032451
GeneOntologyMolecularFunctionstearoyl-CoA 9-desaturase activity

SCD FADS2

1.66e-0441062GO:0004768
GeneOntologyMolecularFunctionacyl-CoA desaturase activity

SCD FADS2

2.76e-0451062GO:0016215
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM4C KDM4E KDM4D KDM4B

3.96e-04651064GO:0016706
GeneOntologyMolecularFunctionarylesterase activity

PON1 PON2

4.13e-0461062GO:0004064
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

KDM4C KDM4E KDM4D SCD FADS2 KDM4B

5.94e-041941066GO:0016705
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 5-kinase activity

PIP5K1A PIPSL

9.81e-0491062GO:0016308
GeneOntologyMolecularFunctionnuclease activity

EXOSC10 DCPS TATDN2 DIS3 AGO3 DCLRE1A

1.46e-032311066GO:0004518
GeneOntologyMolecularFunctionexonuclease activity

EXOSC10 DCPS DIS3 DCLRE1A

1.46e-03921064GO:0004527
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM4C KDM4B

1.49e-03111062GO:0051864
GeneOntologyMolecularFunctionRNA exonuclease activity

EXOSC10 DCPS DIS3

1.75e-03451063GO:0004532
GeneOntologyMolecularFunctiondioxygenase activity

KDM4C KDM4E KDM4D KDM4B

1.85e-03981064GO:0051213
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

SCD FADS2

2.10e-03131062GO:0016717
GeneOntologyMolecularFunctionpeptidase activity

PCSK2 PITRM1 ADAM18 OTUD1 ADAMTS12 CNTNAP5 VASH2 MMP8 MYRF VCPIP1

2.51e-0365410610GO:0008233
GeneOntologyCellularComponentpericentric heterochromatin

KDM4C KDM4E KDM4D KDM4B

2.01e-05321064GO:0005721
DomainJmjN

KDM4C KDM4E KDM4D KDM4B

1.86e-07101044SM00545
DomainJmjN

KDM4C KDM4E KDM4D KDM4B

1.86e-07101044PF02375
DomainJMJN

KDM4C KDM4E KDM4D KDM4B

1.86e-07101044PS51183
DomainJmjN

KDM4C KDM4E KDM4D KDM4B

1.86e-07101044IPR003349
DomainYD

NID2 TENM2 TENM1

1.66e-0651043IPR006530
Domain-

NID2 PON1 PON2 TENM2 TENM1

2.41e-063910452.120.10.30
Domain6-blade_b-propeller_TolB-like

NID2 PON1 PON2 TENM2 TENM1

5.56e-06461045IPR011042
DomainJmjC

KDM4C KDM4E KDM4D KDM4B

8.85e-06241044PF02373
DomainJMJC

KDM4C KDM4E KDM4D KDM4B

2.89e-05321044PS51184
DomainJmjC_dom

KDM4C KDM4E KDM4D KDM4B

2.89e-05321044IPR003347
DomainJmjC

KDM4C KDM4E KDM4D KDM4B

3.28e-05331044SM00558
DomainArylesterase

PON1 PON2

9.18e-0531042PF01731
DomainArylesterase

PON1 PON2

9.18e-0531042IPR002640
DomainGalactose-bd-like

PCSK2 LAMA5 CUL9 PTPRU CNTNAP5

1.80e-04941045IPR008979
DomainTox-GHH_dom

TENM2 TENM1

1.83e-0441042IPR028916
DomainTox-GHH

TENM2 TENM1

1.83e-0441042PF15636
DomainTen_N

TENM2 TENM1

1.83e-0441042IPR009471
DomainTen_N

TENM2 TENM1

1.83e-0441042PF06484
DomainTENEURIN_N

TENM2 TENM1

1.83e-0441042PS51361
DomainQuino_amine_DH_bsu

NID2 TENM2 NBAS

2.39e-04221043IPR011044
DomainEPHD

JADE3 KDM4C KDM4B

2.39e-04221043PS51805
DomainTUDOR

KDM4C LBR KDM4B

4.45e-04271043SM00333
DomainTudor

KDM4C LBR KDM4B

6.10e-04301043IPR002999
DomainFA_desaturase_dom

SCD FADS2

8.41e-0481042IPR005804
DomainFA_desaturase

SCD FADS2

8.41e-0481042PF00487
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM4C KDM4E KDM4D ARID5B KDM4B

3.49e-0729735MM14934
Pubmed

Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.

KDM4C KDM4E KDM4D KDM4B

4.39e-105108421914792
Pubmed

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.

KDM4C KDM4E KDM4D KDM4B

4.39e-105108416738407
Pubmed

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.

KDM4C KDM4E KDM4D KDM4B

2.85e-0811108419144645
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM4C KDM4E KDM4D KDM4B

5.05e-0721108427626377
Pubmed

Identification and characterization of JMJD2 family genes in silico.

KDM4C KDM4D KDM4B

5.78e-076108315138608
Pubmed

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.

PITRM1 PTPRU KDM4D RBFOX1

8.15e-0641108418951430
Pubmed

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.

SZT2 ARHGAP26 TENM2 MSTO1 PEBP4 ADAMTS12 TENM1 CATSPERB IGSF9B KDM4B

9.01e-065521081010737800
Pubmed

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling.

EXOSC10 HYOU1 PON2 DIS3 SCD HS2ST1 FADS2

9.19e-06235108732614325
Pubmed

Association of paraoxonase gene polymorphisms with sperm parameters.

PON1 PON2

9.55e-062108221127310
Pubmed

Repressive histone methylation regulates cardiac myocyte cell cycle exit.

KDM4E KDM4D

9.55e-062108229800554
Pubmed

SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells.

SCD FADS2

9.55e-062108235547771
Pubmed

Paraoxonase genotype and carotid intima-media thickness in children with familial hypercholesterolemia.

PON1 PON2

9.55e-062108216926679
Pubmed

Normalization of gene expression using SYBR green qPCR: a case for paraoxonase 1 and 2 in Alzheimer's disease brains.

PON1 PON2

9.55e-062108221672555
Pubmed

Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-γ production from CD4 T cells.

PON1 PRKDC

9.55e-062108223772025
Pubmed

Divergent iron regulatory states contribute to heterogeneity in breast cancer aggressiveness.

PRKDC C5

9.55e-062108239262774
Pubmed

[A search for association between the polymorphic markers of PON1 and PON2 genes and diabetic nephropathy in patients with type I diabetes mellitus].

PON1 PON2

9.55e-062108216080611
Pubmed

Reduced female fertility due to sequestration of RNA Pol II by pervasive transcription in exosome RNase-depleted oocytes.

EXOSC10 DIS3

9.55e-062108237831603
Pubmed

Lack of association of PON polymorphisms with sporadic ALS in an Italian population.

PON1 PON2

9.55e-062108220381198
Pubmed

Association of PON1 and PON2 polymorphisms with PON1 activity and significant coronary stenosis in a Tunisian population.

PON1 PON2

9.55e-062108223053877
Pubmed

High expression of PRKDC promotes breast cancer cell growth via p38 MAPK signaling and is associated with poor survival.

MAPK14 PRKDC

9.55e-062108231513357
Pubmed

Genetic variants of the paraoxonases (PON1 and PON2) in the Chilean population.

PON1 PON2

9.55e-062108215359538
Pubmed

Increased macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2) expression in Delta6-desaturase knockout (6-DS KO) mice: beneficial effects of arachidonic acid.

PON2 FADS2

9.55e-062108220042190
Pubmed

Circulating Fibroblast Growth Factor-23 Level and Paraoxonase-1 Lactonase Activity in Chronic Hemodialysis Patients: Their Impact on the Incidence of Native AV Fistula Thrombosis.

PON1 FGF23

9.55e-062108227805900
Pubmed

Association of polymorphisms of paraoxonase 1 and 2 genes, alone or in combination, with bone mineral density in community-dwelling Japanese.

PON1 PON2

9.55e-062108212955589
Pubmed

Oxidative stress-related genes in type 2 diabetes: association analysis and their clinical impact.

PON1 PON2

9.55e-062108225991559
Pubmed

Incompatibility in cell adhesion constitutes a barrier to interspecies chimerism.

PRKDC C5

9.55e-062108239181131
Pubmed

[Relationship between paraoxonase 1 55 Met/Leu, paraoxonase 2 148 Ala/Gly genetic polymorphisms and coronary artery disease].

PON1 PON2

9.55e-062108216767666
Pubmed

Isolation of slow-cycling cancer cells from lung patient-derived xenograft using carboxyfluorescein-succinimidyl ester retention-mediated cell sorting.

PRKDC C5

9.55e-062108236924504
Pubmed

SMURF1-mediated ubiquitination of ARHGAP26 promotes ovarian cancer cell invasion and migration.

ARHGAP26 SMURF1

9.55e-062108231004081
Pubmed

GATA Factor-Dependent Positive-Feedback Circuit in Acute Myeloid Leukemia Cells.

GATA2 MAPK14

9.55e-062108227545880
Pubmed

Human tissue distribution of paraoxonases 1 and 2 mRNA.

PON1 PON2

9.55e-062108220503442
Pubmed

Paraoxonase gene cluster is a genetic marker for early microvascular complications in type 1 diabetes.

PON1 PON2

9.55e-062108211918623
Pubmed

Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence.

PON1 PON2

9.55e-06210829714608
Pubmed

Targeting ferritinophagy impairs quiescent cancer stem cells in acute myeloid leukemia in vitro and in vivo models.

PRKDC C5

9.55e-062108239047119
Pubmed

Paraoxonase, a cardioprotective enzyme: continuing issues.

PON1 PON2

9.55e-062108215166781
Pubmed

[Association between paraoxonase-1 and paraoxonase-2 polymorphisms and the risk of acute myocardial infarction].

PON1 PON2

9.55e-062108218361900
Pubmed

Interactions and associations of paraoxonase gene cluster polymorphisms with myocardial infarction in a Pakistani population.

PON1 PON2

9.55e-062108217309646
Pubmed

Pregranulosa cell-derived FGF23 protects oocytes from premature apoptosis during primordial follicle formation by inhibiting p38 MAPK in mice.

FGF23 MAPK14

9.55e-062108237142227
Pubmed

Kdm4d mutant mice show impaired sperm motility and subfertility.

KDM4E KDM4D

9.55e-062108239034148
Pubmed

Association of paraoxonase polymorphisms with carotid artery atherosclerosis in essential hypertension patients.

PON1 PON2

9.55e-062108224301778
Pubmed

Paraoxonase 1 and 2 gene variants and the ischemic stroke risk in Gran Canaria population: an association study and meta-analysis.

PON1 PON2

9.55e-062108226978533
Pubmed

Expression of SCD and FADS2 Is Lower in the Necrotic Core and Growing Tumor Area than in the Peritumoral Area of Glioblastoma Multiforme.

SCD FADS2

9.55e-062108232392704
Pubmed

Paraoxonase gene polymorphism and the risk for Alzheimer's disease in the polish population.

PON1 PON2

9.55e-062108221757906
Pubmed

Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling.

KDM4E KDM4D

9.55e-062108232094404
Pubmed

Risk of carotid atherosclerosis is associated with low serum paraoxonase (PON1) activity among arsenic exposed residents in Southwestern Taiwan.

PON1 PON2

9.55e-062108219371607
Pubmed

Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.

KDM4C KDM4B

9.55e-062108224361252
Pubmed

Association between the severity of angiographic coronary artery disease and paraoxonase gene polymorphisms in the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study.

PON1 PON2

9.55e-062108212454802
Pubmed

Association of paraoxonase gene polymorphisms with diabetic nephropathy and retinopathy.

PON1 PON2

9.55e-062108224100645
Pubmed

Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.

KDM4E KDM4D

9.55e-062108230472235
Pubmed

Induction of OTUD1 by RNA viruses potently inhibits innate immune responses by promoting degradation of the MAVS/TRAF3/TRAF6 signalosome.

OTUD1 SMURF1

9.55e-062108229734366
Pubmed

FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response.

SCD FADS2

9.55e-062108238849435
Pubmed

Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma.

PRKDC C5

9.55e-062108237057874
Pubmed

Assessment of serum paraoxonase and arylesterase activity in patients with endometrial cancer.

PON1 PON2

9.55e-062108220099504
Pubmed

p38 links RAS to GATA2.

GATA2 MAPK14

9.55e-062108225092790
Pubmed

The role of polymorphisms within paraoxonases (192 Gln/Arg in PON1 and 311Ser/Cys in PON2) in the modulation of cardiovascular risk: a pilot study.

PON1 PON2

9.55e-062108219939821
Pubmed

RNA-regulatory exosome complex confers cellular survival to promote erythropoiesis.

EXOSC10 DIS3

9.55e-062108234059908
Pubmed

Four genetic polymorphisms of paraoxonase gene and risk of coronary heart disease: a meta-analysis based on 88 case-control studies.

PON1 PON2

9.55e-062108221146823
Pubmed

Detecting the polymorphisms of paraoxonase (PON) cluster in Chinese Han population based on a rapid method.

PON1 PON2

9.55e-062108216185677
Pubmed

Serum paraoxonase activity and paraoxonase gene polymorphism in type 2 diabetic patients with or without vascular complications.

PON1 PON2

9.55e-062108212442067
Pubmed

Genetic variations of the paraoxonase gene in patients with coronary artery disease.

PON1 PON2

9.55e-062108211676977
Pubmed

Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants.

PRKDC C5

9.55e-062108231543464
Pubmed

Strong KDM4B and KDM4D Expression Associates with Radioresistance and Aggressive Phenotype in Classical Hodgkin Lymphoma.

KDM4D KDM4B

9.55e-062108227630312
Pubmed

Polymorphisms of the paraoxonase gene and risk of preterm delivery.

PON1 PON2

9.55e-062108215232408
Pubmed

Paraoxonase gene polymorphisms and sporadic ALS.

PON1 PON2

9.55e-062108216822965
Pubmed

Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies.

PON1 PON2

9.55e-062108215001326
Pubmed

Polymorphisms of pon1 and pon2 genes in hemodialyzed patients.

PON1 PON2

9.55e-062108221620813
Pubmed

Associations between genetic polymorphisms of paraoxonase genes and coronary artery disease in a Taiwanese population.

PON1 PON2

9.55e-062108223742759
Pubmed

The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel.

HYOU1 SCNN1A

9.55e-062108223645669
Pubmed

Paraoxonase gene polymorphisms and stroke severity.

PON1 PON2

9.55e-062108219930448
Pubmed

Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling.

KDM4E KDM4D

9.55e-062108235027670
Pubmed

Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation.

KDM4E KDM4D

9.55e-062108225417163
Pubmed

Paraoxonase gene polymorphism in south-western Korean population.

PON1 PON2

9.55e-062108219654933
Pubmed

The paraoxonase gene polymorphism in stroke patients and lipid profile.

PON1 PON2

9.55e-062108217854416
Pubmed

Polymorphisms of paraoxonase 1 and 2 genes and the risk of multiple sclerosis in the Polish population.

PON1 PON2

9.55e-062108223487294
Pubmed

Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency.

PRKDC C5

9.55e-062108234702956
Pubmed

An in vivo neuroimmune organoid model to study human microglia phenotypes.

PRKDC C5

9.55e-062108237172564
Pubmed

Paraoxonase (PON)1 192R allele carriage is associated with reduced risk of inflammatory bowel disease.

PON1 PON2

9.55e-062108217436100
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

PTPRU TENM2 SEMA6D TENM1 IGSF9B

9.89e-0691108528558017
Pubmed

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

KDM4C KDM4D KDM4B

1.03e-0514108316603238
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

EXOSC10 HYOU1 PITRM1 ARHGAP26 PON2 PTPRU DIS3 IGF2BP2 MAPK14 PIP5K1A PRKDC PIPSL VCPIP1

1.07e-059741081328675297
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

RASA1 ATXN7L1 SMURF1 PON2 CHD2 PTPRB FAM168A TBC1D22A HS2ST1 ARID5B SCNN1A DIP2C PIP5K1A IGSF9B LRBA KDM4B

1.45e-0514891081628611215
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM4C KDM4E KDM4D KDM4B

1.67e-0549108434368113
Pubmed

Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients.

PON1 PON2 SCNN1A C5

2.47e-0554108420536507
Pubmed

Paraoxonase and atherosclerosis-related cardiovascular diseases.

PON1 PON2

2.86e-053108227771368
Pubmed

Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study.

SCD FADS2

2.86e-053108220395685
Pubmed

[Study of the association between paraoxonase1 55 Met/Leu, paraoxonase2 148 Ala/Gly and manganese superoxide dismutase (MnSOD) 9 Ala/Val genetic polymorphisms and coronary heart disease].

PON1 PON2

2.86e-053108217299970
Pubmed

[Paraoxonase: The Universal Factor of Antioxidant Defense in Human Body].

PON1 PON2

2.86e-053108229308836
Pubmed

Inflammation, infection, cancer and all that…the role of paraoxonases.

PON1 PON2

2.86e-053108225038992
Pubmed

Ocular distribution of antioxidant enzyme paraoxonase & its alteration in cataractous lens & diabetic retina.

PON1 PON2

2.86e-053108228862184
Pubmed

Association Between Paraoxonase Gene Polymorphisms and Intracerebral Hemorrhage in a Korean Population.

PON1 PON2

2.86e-053108226227792
Pubmed

The three-gene paraoxonase family: physiologic roles, actions and regulation.

PON1 PON2

2.86e-053108220934178
Pubmed

Comparative expression analysis reveals differences in the regulation of intestinal paraoxonase family members.

PON1 PON2

2.86e-053108219401157
Pubmed

Paraoxonase gene polymorphisms and haplotype analysis in a stroke population.

PON1 PON2

2.86e-053108216551349
Pubmed

Genetic variation in lipid desaturases and its impact on the development of human disease.

SCD FADS2

2.86e-053108220565855
Pubmed

Continuous reduction of plasma paraoxonase activity with increasing dialysis vintage in hemodialysis patients.

PON1 PON2

2.86e-053108221118365
Pubmed

Effects of PON polymorphisms and haplotypes on molecular phenotype in Mexican-American mothers and children.

PON1 PON2

2.86e-053108220839225
Pubmed

Regulation of desaturase expression in HL60 cells.

SCD FADS2

2.86e-053108217852835
Pubmed

Paraoxonase gene cluster variations associated with coronary heart disease in Chinese Han women.

PON1 PON2

2.86e-053108216117861
Pubmed

Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.

KDM4C KDM4B

2.86e-053108217611647
Pubmed

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.

KDM4E KDM4D

2.86e-053108221555854
GeneFamilyPHD finger proteins|Lysine demethylases

KDM4C KDM4E KDM4D KDM4B

2.58e-0624744485
GeneFamilyParaoxonases

PON1 PON2

4.94e-053742463
GeneFamilyFatty acid desaturases

SCD FADS2

4.55e-048742553
GeneFamilyTudor domain containing

KDM4C LBR KDM4B

4.63e-0437743780
GeneFamilyExosome complex

EXOSC10 DIS3

1.06e-0312742817
GeneFamilyOTU domain containing

OTUD1 VCPIP1

2.16e-0317742669
GeneFamilyHeat shock 70kDa proteins

HYOU1 HSPA12A

2.16e-0317742583
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRU PTPRB

3.30e-0321742813
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK2 GLDN FRMD1 HSPA12A SEMA6D SCD RASSF4

5.14e-071961087b6226163d9fc93ecfff2115bb74408303a000490
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CACNA1F NID2 NLGN1 PTPRU SCNN1A MYRF PHLDB2

5.70e-071991087d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

PCSK2 NLGN1 TTC6 PEBP4 SCD SCNN1A

5.84e-061841086369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLDN NLGN1 KCNIP1 TENM2 CNTNAP5 TENM1

5.84e-061841086658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

LAMA5 KCNIP1 SEMA6D SCNN1A MYRF PHLDB2

5.84e-061841086561592edc3083fad41b91811151b442207c65dd9
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

LAMA5 KCNIP1 PEBP4 SCNN1A MYRF PHLDB2

6.02e-0618510860563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

LAMA5 KCNIP1 PEBP4 SCNN1A MYRF PHLDB2

6.40e-061871086fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SZT2 KDM4C SMURF1 MSTO1 PTPRB SEMA6D

6.40e-0618710863699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SZT2 KDM4C SMURF1 MSTO1 PTPRB SEMA6D

6.40e-061871086033ba52c0c2f9978784947098fa697368ae44834
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

LAMA5 KCNIP1 SEMA6D SCNN1A MYRF PHLDB2

6.40e-06187108677f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

HYOU1 LBR PARP14 NBAS PRKDC LRBA

7.23e-0619110869454f642c3621370fa23640b631301346b300950
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

PCSK2 NLGN1 TTC6 PEBP4 SCD SCNN1A

7.23e-061911086276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA5 KCNIP1 SEMA6D SCNN1A MYRF PHLDB2

8.14e-061951086a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCSK2 HSPA12A SEMA6D SCD TENM1 RASSF4

8.62e-061971086e239caae24f40564a24ad909754f5436f767ccdb
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

KDM4C ARHGAP26 NBAS TBC1D22A DIP2C LRBA

9.13e-06199108694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

CACNA1F PTPRU SCNN1A C5 MYRF PHLDB2

9.40e-0620010862dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CACNA1F NID2 PTPRU SCNN1A MYRF PHLDB2

9.40e-0620010868683445ad5b70748c4a1f12eb77d47623085147e
ToppCellBiopsy_Control_(H.)-Epithelial-AT1|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LAMA5 KCNIP1 SEMA6D SCNN1A MYRF PHLDB2

9.40e-0620010863a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLGN1 TTC6 SCNN1A C5 MYRF

1.64e-0513010856434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 GLDN PEBP4 TNNI3K PTPRB

2.11e-051371085b831d917f5073ccff158662adb281d34f023126a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 GLDN PEBP4 TNNI3K PTPRB

2.11e-051371085cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CELF6 GLDN PEBP4 TNNI3K PTPRB

2.11e-0513710855d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 PON1 PON2 RBFOX1 IGSF9B

2.96e-051471085989a48bda98fbff398985397a6b1189a4cbc80e7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 PON1 PON2 RBFOX1 IGSF9B

2.96e-051471085f6681c849c4c06154548bd29a094f202d1c946c2
ToppCellCOVID-19-lung-Mesothelial|lung / Disease (COVID-19 only), tissue and cell type

NLGN1 HSPA12A SEMA6D RBFOX1 MYRF

3.93e-051561085e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCellPBMC-Severe-Myeloid-cDC-cDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GLDN ZNF619 MS4A4A STS ZNF341

4.84e-051631085ec8336b68c8369e27d507c04c827be07bb48a7f6
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

OTUD1 LAMA5 PARP14 STS PHLDB2

5.75e-051691085665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

OTUD1 LAMA5 PARP14 STS PHLDB2

5.75e-0516910856614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCell356C-Myeloid-Dendritic-cDC_activated|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

JADE3 GATA2 LAMA5 VASH2 RASSF4

5.91e-051701085513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CACNA1F CORO2A ARHGAP26 PLEKHN1 SCNN1A

6.25e-051721085a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4-5_RORB_ASCL1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GLDN NLGN1 KCNIP1 TENM1 PHLDB2

6.42e-0517310852e35bf2b5534a289d93a09faae660f665c131062
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PCSK2 NID2 KCNIP1 HSPA12A IGSF9B

6.78e-051751085bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CACNA1F CORO2A PLEKHN1 FCHO1 SCNN1A

6.78e-051751085f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PCSK2 NID2 KCNIP1 HSPA12A IGSF9B

6.78e-0517510858b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PCSK2 NID2 KCNIP1 HSPA12A IGSF9B

6.78e-0517510850b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 STS SEMA6D MYRF PHLDB2

6.96e-051761085458720776b0151cd55acc352d509599cb62f0ca8
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

HYOU1 PARP14 AGO3 SCD IGSF9B

6.96e-0517610853de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

HYOU1 NBAS AGO3 SCD IGSF9B

7.15e-05177108582fdd6185b368f54f03de389427cbe3071d21a99
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1F NLGN1 SCNN1A MYRF PHLDB2

7.95e-051811085b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PON2 NLGN1 SCNN1A MYRF PHLDB2

8.37e-051831085274483009b309289e4cb84beedf6806430db6ff6
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLGN1 SCNN1A C5 MYRF PHLDB2

8.37e-051831085ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 TNNI3K SEMA6D MYRF PHLDB2

8.37e-0518310856821dca076318115d360ff426eb1218cfe104063
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA5 KCNIP1 SCNN1A MYRF PHLDB2

8.59e-05184108557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCPS CORO2A ATXN7L1 FCHO1 PAQR7

8.59e-051841085185b49630da61cbf45c0926d1b992943296d2a54
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 SEMA6D RBFOX1 SCNN1A LRBA

8.59e-051841085e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA5 KCNIP1 SCNN1A MYRF PHLDB2

8.59e-051841085d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA5 KCNIP1 SEMA6D MYRF PHLDB2

8.81e-0518510851c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell18-Distal-Epithelial-Neuroendocrine|Distal / Age, Tissue, Lineage and Cell class

PCSK2 PON1 CFAP65 RBFOX1 SCNN1A

8.81e-051851085f8fc7b12b4e18d23d84e95488be93c4352d325f3
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLGN1 SCNN1A C5 MYRF PHLDB2

9.04e-0518610854e94158db52df41d71e67b02b9895a358eebee0f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 NLGN1 SIM2 TENM1 DIP2C

9.04e-051861085f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCelldroplet-Fat-SCAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SZT2 PON1 TTC6 ZSWIM9 SLC25A35

9.27e-0518710855fada3c5a58c1890029ccbfff2608b33f8cd2df7
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

ZNF619 MS4A4A MAPK14 FADS2 RASSF4

9.27e-0518710853c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCelldroplet-Fat-SCAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SZT2 PON1 TTC6 ZSWIM9 SLC25A35

9.27e-051871085766e808138fc2cd623c2e6d57fcb5c7378da0e03
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NID2 NLGN1 ADAMTS12 ZSWIM9 RBFOX1

9.27e-0518710858e8b147258982b359447add5027318f5b6d51963
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 NLGN1 SIM2 TENM1 DIP2C

9.27e-051871085c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLGN1 SCNN1A C5 MYRF PHLDB2

9.27e-05187108558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NLGN1 SCNN1A C5 MYRF PHLDB2

9.27e-051871085ff26a533d310126521efe1d05cf8b9d32e524550
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|368C / Donor, Lineage, Cell class and subclass (all cells)

CHAF1B SMURF1 LAMA5 SCNN1A LRBA

9.27e-051871085b827d9da7032bf051756ddf88352af922eb0f87b
ToppCelldroplet-Fat-SCAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SZT2 PON1 TTC6 ZSWIM9 SLC25A35

9.27e-051871085f49d06600060deeb2fc1b1da5b93496535f20104
ToppCell368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|368C / Donor, Lineage, Cell class and subclass (all cells)

CHAF1B SMURF1 LAMA5 SCNN1A LRBA

9.27e-05187108561c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN1 SIM2 IGF2BP2 TENM1 DIP2C

9.50e-051881085af740fa78542438fdff627ea1f74f4eee43316be
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 SEMA6D RBFOX1 SCNN1A LRBA

9.74e-051891085f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCellcellseq-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LBR MAPK14 XPO6 TENM1 MMP8

9.74e-051891085fedab592be1d6520325b8c1b659b0a4dc3f4fe4d
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NLGN1 TENM2 RBFOX1 DIP2C PHLDB2

9.74e-0518910850a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

LAMA5 KCNIP1 DIP2C MYRF PHLDB2

9.74e-0518910855a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PON2 SIM2 RBFOX1 ARID5B SCNN1A

9.99e-051901085bf4511395fa97efd1c1cd17cc9bebb0271ee7f0e
ToppCell(7)_Epithelial-D_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PCSK2 PON2 PEBP4 SCD SCNN1A

9.99e-051901085832d6d3ad14665e50623afe1b8586ccae1a97de5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PON2 SIM2 RBFOX1 ARID5B SCNN1A

9.99e-051901085b6b8964b4910083499681b5fdf554e127b6a4c4e
ToppCellGlobus_pallidus-Neuronal|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CELF6 TENM2 FCHO1 EFNA3 TENM1

9.99e-051901085416de85d8841dac883faa6f5339b2fb461a09e82
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SIM2 SEMA6D RBFOX1 SCNN1A LRBA

9.99e-051901085b94df372bc08de11585b2467dba8c8fffff5cd92
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PON2 TTC6 PEBP4 SCNN1A MYRF

1.02e-041911085ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 PLEKHN1 TENM2 RBFOX1 MYRF

1.05e-0419210852f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

CELF6 TENM2 CNTNAP5 RBFOX1 TENM1

1.05e-0419210854c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

ATXN7L1 NLGN1 TBC1D22A DIP2C LRBA

1.05e-041921085e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RASA1 KDM4C ARHGAP26 FAM168A LRBA

1.07e-041931085779276e775cb2492e8dd36436295a536084a6415
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN1 IGF2BP2 SCNN1A DIP2C LRBA

1.07e-0419310853866667dd221612589ae50f5c52f73a183a49ce6
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PCSK2 CHD2 PEBP4 SCNN1A CATSPERB

1.10e-04194108597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

LAMA5 PEBP4 SEMA6D SCNN1A MYRF

1.13e-041951085569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

KDM4C SMURF1 TBC1D22A DIP2C LRBA

1.16e-041961085ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

OTUD1 LAMA5 SEMA6D MYRF PHLDB2

1.16e-0419610856c99d29162848161c1f166a032320f87a5d5a631
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

PCSK2 TFAP2D GATA2 TENM2 TENM1

1.16e-0419610850767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell(7)_Epithelial-B_(AT2)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

PCSK2 PEBP4 SCD SCNN1A C5

1.16e-041961085345d4cc062b43bca9d506fbf23363469a9ba496f
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KDM4C GATA2 ARID5B TENM1 LRBA

1.18e-04197108557ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA5 KCNIP1 SEMA6D MYRF PHLDB2

1.18e-0419710858d5097898dd01cedb04cb694cb480c931e08462c
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CACNA1F NID2 PTPRU SCNN1A PHLDB2

1.21e-041981085b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

NID2 PON2 PTPRU SCNN1A PHLDB2

1.21e-0419810859b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

OTUD1 LAMA5 SEMA6D MYRF PHLDB2

1.21e-0419810850047a9ef7684230ac5179efea94461480e90bdaf
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NLGN1 TENM2 ADAMTS12 SEMA6D PHLDB2

1.24e-0419910853835452e4848d7f7dd8651c17b746b271ef39688
ToppCellBiopsy_IPF-Epithelial-Transitional_AT2|Biopsy_IPF / Sample group, Lineage and Cell type

PCSK2 PON2 LAMA5 PEBP4 SCNN1A

1.24e-04199108583ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NLGN1 OMD TENM2 ADAMTS12 SEMA6D

1.24e-04199108545c3b853900d8c3d5965117d904e3714100138bc
ToppCellTracheal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NLGN1 TENM2 ADAMTS12 SEMA6D PHLDB2

1.24e-0419910859c2db0bb94cba71a3cc1827844da090e213e0258
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PCSK2 PEBP4 SCD FADS2 C5

1.24e-0419910852dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CACNA1F NID2 PTPRU SCNN1A PHLDB2

1.27e-042001085ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell390C-Lymphocytic-NK_cells-NK_cell_A2|390C / Donor, Lineage, Cell class and subclass (all cells)

MARS2 ZNF619 MTRF1 KDM4B

1.54e-041111084dfbdeadad321392d359e6fb7112b28b043a4b874
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_activate-7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JADE3 FGF23 KDM4D DIP2C

2.51e-041261084518a6e4919981b556ce6b451a91270dba976bc75
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32

TFAP2D PTPRU CNTNAP5 IGSF9B

2.66e-0412810847e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Striatum / BrainAtlas - Mouse McCarroll V32

TFAP2D PTPRU CNTNAP5 IGSF9B

2.66e-041281084a876303c852db2af9418d1a1711d7c950805018a
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32

TFAP2D PTPRU CNTNAP5 IGSF9B

2.66e-041281084388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCellE18.5-samps-Epithelial-Alveolar_epithelial-AT1|E18.5-samps / Age Group, Lineage, Cell class and subclass

PANX3 PEBP4 SCNN1A MYRF

2.83e-041301084eb16a8f8f62add5fdd29c78d4608b6d1a06767f1
ToppCellLPS-IL1RA-Endothelial-Epi-like-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PCSK2 KCNIP1 EFNA3 DCLRE1A

3.55e-0413810845f8ac8f67e34a7cf560099208e6884102532391e
DrugDrofenine hydrochloride [548-66-3]; Up 200; 11.4uM; PC3; HT_HG-U133A

CDHR2 ATXN7L1 ARHGAP26 SMURF1 STS HS2ST1 DIP2C KDM4B

3.83e-0619610687129_UP
Drug16-phenyl tetranor Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A

SZT2 FRMD1 DIS3 HSPA12A MAPK14 SEMA6D TBC1D22A C5

3.98e-0619710687505_UP
Drugmethyl phenyl phosphate

PON1 PON2

2.15e-0521062CID000301276
DrugBcdA

PON1 PON2

2.15e-0521062CID000065116
Drug5,6,7,8-tetrahydroxy-4-oxooctanal

PON1 PON2

2.15e-0521062ctd:C550995
DrugNSC 2885

PON1 PON2

2.15e-0521062CID000070425
Drug0317956-0000 [391210-11-0]; Down 200; 10uM; MCF7; HT_HG-U133A

SZT2 CDHR2 SIM2 OMD MAPK14 STS KDM4B

3.06e-0519010673966_DN
DrugThioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A

SZT2 CDHR2 KDM4C FRMD1 STS FAM168A VCPIP1

3.17e-0519110673392_UP
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A

SZT2 KDM4C FGF23 SEMA6D TBC1D22A RBFOX1 KDM4B

3.74e-0519610675088_UP
DrugTranexamic acid [1197-18-8]; Down 200; 25.4uM; MCF7; HT_HG-U133A

SMURF1 PTPRU GPR107 TMEM62 FAM168A C5 KDM4B

3.74e-0519610676238_DN
Drug3-nitropropionic acid; Up 200; 10uM; MCF7; HT_HG-U133A

ADAM18 FRMD1 ADAMTS12 SEMA6D SCNN1A TENM1 MMP8

3.86e-0519710676367_UP
Druggenistein; Down 200; 10uM; MCF7; HT_HG-U133A

GATA2 PTPRU GPR107 TBC1D22A VASH2 DCLRE1A C5

3.86e-0519710676952_DN
DrugAlprostadil [745-65-3]; Down 200; 11.2uM; PC3; HT_HG-U133A

CDHR2 KDM4C NLGN1 PTPRB STS RBFOX1 MYRF

3.99e-0519810674099_DN
Drug16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A

ADAM18 CHST8 EFNA3 TBC1D22A FADS2 KDM4B VCPIP1

3.99e-0519810677505_DN
DrugPHA-00767505E [723337-45-9]; Up 200; 10uM; MCF7; HT_HG-U133A

PON1 KCNIP1 FRMD1 FGF23 MAPK14 VASH2 KDM4B

3.99e-0519810676550_UP
DrugDiclofenac sodium [15307-79-6]; Up 200; 12.6uM; PC3; HT_HG-U133A

CDHR2 ARHGAP26 SMURF1 PON1 STS TBC1D22A TENM1

3.99e-0519810675861_UP
DrugPirlindole mesylate [60762-57-4]; Up 200; 12.4uM; MCF7; HT_HG-U133A

CDHR2 OMD FRMD1 DIS3 EFNA3 PTPRB HS2ST1

4.12e-0519910676519_UP
Drugketene

PON1 PON2 MMP8

6.36e-05171063CID000010038
Drugd22-29

PON1 PON2

6.42e-0531062CID000077709
DrugI2-15

SCD FADS2

6.42e-0531062CID000013388
DrugO,O-diethyl O-(4-carbamoylphenyl)phosphate

PON1 PON2

6.42e-0531062CID000151413
Drug1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine

SCD FADS2

6.42e-0531062ctd:C078632
Drugxylenol orange

PON1 PON2 RBFOX1

1.06e-04201063CID000073041
Drugo-nitrophenylbutyrate

PON1 PON2

1.28e-0441062CID000075600
Drugphenyl acetate

PON1 PON2

1.28e-0441062ctd:C570634
DrugTetriso

PON1 PON2

1.28e-0441062CID000161384
Drug5-hydroxyeicosatetraenoic acid lactone

PON1 PON2

1.28e-0441062ctd:C047651
Drug9-hexadecenal

SCD FADS2

1.28e-0441062CID000092066
Drug4-hydroxyphenyl acetate

PON1 PON2

1.28e-0441062CID000096009
Drugcoroxon

PON1 PON2

1.28e-0441062CID000009453
Drugmethyl phenylphosphonate

PON1 PON2

1.28e-0441062CID000024913
DrugAC1L9LQQ

LBR SCD FADS2 C5

1.45e-04571064CID000448224
Drug3,5,6-trichloro-2-pyridinol

PON1 PON2 MAPK14

1.62e-04231063CID000023017
DrugC16:1n-7

PON1 PIGV SCD FADS2

1.66e-04591064CID000004668
Drugtrinexapac-ethyl

PON1 PON2 C5

2.09e-04251063CID000092421
Drugalamos

PON1 PON2 LBR

2.09e-04251063CID000079914
DrugAC1Q6SGD

PON1 PON2

2.13e-0451062CID000016775
DrugAC1L1V7J

PON1 PON2

2.13e-0451062CID000036158
Drugphenylacetic acid

PON1 PON2

2.13e-0451062ctd:C025136
Drug1-penten-3-ol

SCD FADS2

2.13e-0451062CID000012020
Drugvamidothion

PON1 PON2

2.13e-0451062CID000560193
Drugdiethylaminoethanethiol

PON1 PON2

2.13e-0451062CID000016031
Drugfensulfothion

PON1 PON2

2.13e-0451062CID000008292
Drugmethyl sterculate

SCD FADS2

2.13e-0451062CID000115261
Drug16-methylprogesterone

SCD FADS2

2.13e-0451062CID000134874
Drug1,5,9-triazacyclododecane

PON1 PON2

2.13e-0451062CID000470778
Drugcrufomate

PON1 PON2

2.13e-0451062CID000009300
DrugGSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A

NID2 MTRF1 TMEM62 EFNA3 STS VASH2

2.74e-0419110667070_DN
DrugCimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A

KDM4C HSPA12A RBFOX1 VASH2 FADS2 IQCK

2.90e-0419310661464_DN
Drugprochlorperazine dimaleate salt; Down 200; 10uM; HL60; HT_HG-U133A

CDHR2 ARHGAP26 OMD TBC1D22A RBFOX1 IQCK

2.90e-0419310662675_DN
DrugAlprenolol hydrochloride [13707-88-5]; Up 200; 14uM; MCF7; HT_HG-U133A

CDHR2 KCNIP1 CHST8 EFNA3 STS FADS2

2.90e-0419310666789_UP
Drug(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; HL60; HT_HG-U133A

CDHR2 SMURF1 OMD STS TBC1D22A RBFOX1

2.98e-0419410663015_DN
DrugLY 294002; Up 200; 10uM; PC3; HT_HG-U133A

SZT2 CUL9 SIM2 FGF23 FADS2 MYRF

2.98e-0419410661239_UP
Drug5194442; Up 200; 20uM; PC3; HT_HG-U133A

KDM4C ARHGAP26 PTPRU KDM4D EFNA3 TBC1D22A

2.98e-0419410666553_UP
DrugRoxithromycin [80214-83-1]; Down 200; 4.8uM; PC3; HT_HG-U133A

GATA2 MTRF1 HSPA12A MAPK14 STS C5

2.98e-0419410664192_DN
DrugIsradipine [75695-93-1]; Down 200; 10.8uM; PC3; HT_HG-U133A

GPR107 KDM4D TBC1D22A FADS2 DCLRE1A C5

2.98e-0419410666347_DN
DrugKarakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A

RASA1 DIS3 CHST8 FGF23 EFNA3 TBC1D22A

3.06e-0419510666059_DN
DrugS(+)-Terguride [37686-84-3]; Up 200; 11.8uM; PC3; HT_HG-U133A

CDHR2 CHST8 EFNA3 FADS2 MYRF KDM4B

3.06e-0419510666299_UP
Drughaloperidol; Down 200; 10uM; HL60; HT_HG-U133A

ARHGAP26 GATA2 SMURF1 NLGN1 STS RBFOX1

3.06e-0419510662663_DN
DrugHomosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A

ARHGAP26 PON1 FRMD1 AGO3 RBFOX1 SCNN1A

3.06e-0419510664355_UP
DrugAmidopyrine [58-15-1]; Down 200; 17.2uM; PC3; HT_HG-U133A

KDM4C GATA2 SMURF1 GPR107 MAPK14 IQCK

3.06e-0419510664481_DN
DrugTriflusal [322-79-2]; Down 200; 16.2uM; MCF7; HT_HG-U133A

PTPRU FCHO1 GPR107 TMEM62 DCLRE1A KDM4B

3.06e-0419510667451_DN
DrugAmiodarone hydrochloride [19774-82-4]; Up 200; 5.8uM; MCF7; HT_HG-U133A

SZT2 ATXN7L1 NLGN1 CHST8 SCNN1A KDM4B

3.15e-0419610665253_UP
Drugestradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A

GATA2 SMURF1 KCNIP1 FRMD1 EFNA3 VASH2

3.15e-0419610665568_DN
DrugAcemetacin [53164-05-9]; Up 200; 9.6uM; PC3; HT_HG-U133A

KDM4C PTPRU EFNA3 STS TBC1D22A RBFOX1

3.15e-0419610666361_UP
DrugFoliosidine [2520-38-9]; Down 200; 13uM; MCF7; HT_HG-U133A

KDM4C SIM2 GPR107 EFNA3 SEMA6D TBC1D22A

3.15e-0419610666057_DN
DrugBenzthiazide [91-33-8]; Up 200; 9.2uM; PC3; HT_HG-U133A

NID2 SZT2 PON1 PTPRB STS RASSF4

3.15e-0419610666607_UP
DrugNialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A

KDM4C GPR107 HSPA12A EFNA3 MAPK14 VASH2

3.15e-0419610664347_DN
DrugSolasodine [126-17-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

KDM4C ARHGAP26 CUL9 FRMD1 CHST8 EFNA3

3.15e-0419610663830_DN
DrugSpectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; MCF7; HT_HG-U133A

ADAM18 CUL9 ADAMTS12 EFNA3 MAPK14 FADS2

3.15e-0419610664773_UP
DrugMeglumine [6284-40-8]; Down 200; 20.4uM; MCF7; HT_HG-U133A

CUL9 PTPRU SIM2 HSPA12A TBC1D22A VASH2

3.15e-0419610666445_DN
DrugTimolol maleate salt [26921-17-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A

SMURF1 NLGN1 TMEM62 MAPK14 TBC1D22A VCPIP1

3.15e-0419610666483_DN
DrugCarbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A

SZT2 SIM2 FRMD1 SEMA6D TBC1D22A RBFOX1

3.15e-0419610663380_UP
Drug2-MeNH

PON1 PON2

3.18e-0461062CID000159841
Drugaminoparathion

PON1 PON2

3.18e-0461062CID000000220
Drug7-hydroxytestosterone

SCD FADS2

3.18e-0461062CID000065541
Drugtris(p-nitrophenyl) phosphate

PON1 PON2

3.18e-0461062CID000077473
Drugvinyl phosphate

PON1 PON2

3.18e-0461062CID000135020
DrugPm70

PON1 PON2

3.18e-0461062CID006334707
Drugdiethyl 4-methylbenzylphosphonate

PON1 PON2

3.18e-0461062CID000003050
Drugnylon 11

PON1 PON2

3.18e-0461062CID000017083
DrugC19:0

SCD FADS2

3.18e-0461062CID000012591
Drugphosphinate

PON1 PON2 LBR MMP8

3.21e-04701064CID000022497
DrugMexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; MCF7; HT_HG-U133A

CUL9 SIM2 GPR107 CHST8 EFNA3 TBC1D22A

3.24e-0419710663862_DN
DrugPiperidolate hydrochloride [129-77-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A

FRMD1 EFNA3 STS SEMA6D RBFOX1 TENM1

3.24e-0419710663551_UP
DrugGlycopyrrolate [596-51-0]; Down 200; 10uM; PC3; HT_HG-U133A

ARHGAP26 CUL9 KDM4D HS2ST1 MYRF IQCK

3.24e-0419710667386_DN
DrugMethantheline bromide [53-46-3]; Up 200; 9.6uM; PC3; HT_HG-U133A

SMURF1 KCNIP1 FRMD1 FGF23 MMP8 MYRF

3.24e-0419710665780_UP
DrugTrichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A

JADE3 STS FAM168A TBC1D22A SCNN1A FADS2

3.24e-0419710661675_UP
DrugAminopurine, 6-benzyl [1214-39-7]; Up 200; 17.8uM; HL60; HT_HG-U133A

NLGN1 OMD FGF23 STS KDM4B IQCK

3.24e-0419710662351_UP
DrugVincamine [1617-90-9]; Up 200; 11.2uM; MCF7; HT_HG-U133A

PON1 SIM2 OMD RBFOX1 FADS2 MMP8

3.24e-0419710662327_UP
DrugTomatidine [77-59-8]; Up 200; 9.6uM; MCF7; HT_HG-U133A

CHST8 MAPK14 RBFOX1 TENM1 CATSPERB KDM4B

3.24e-0419710662746_UP
DrugBrinzolamide [138890-62-7]; Down 200; 10.4uM; MCF7; HT_HG-U133A

SMURF1 NLGN1 DIS3 EFNA3 TBC1D22A VASH2

3.24e-0419710663230_DN
DrugCP-319743 [172078-87-4]; Up 200; 10uM; PC3; HT_HG-U133A

SZT2 CORO2A KDM4C ATXN7L1 PTPRU C5

3.24e-0419710667491_UP
DrugLY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A

PTPRU FCHO1 MTRF1 EFNA3 TBC1D22A HS2ST1

3.24e-0419710661641_DN
DrugMephenesin [59-47-2]; Down 200; 22uM; PC3; HT_HG-U133A

KDM4C GATA2 CUL9 MAPK14 MYRF IQCK

3.24e-0419710667374_DN
Drugvaldecoxib; Down 200; 10uM; PC3; HT_HG-U133A

CORO2A GPR107 CHST8 EFNA3 MAPK14 MYRF

3.24e-0419710666408_DN
DrugPhenindione [83-12-5]; Up 200; 18uM; PC3; HT_HG-U133A

NID2 SMURF1 GPR107 EFNA3 TBC1D22A MYRF

3.24e-0419710667289_UP
DrugEnalapril maleate [76095-16-4]; Up 200; 8.2uM; PC3; HT_HG-U133A

GATA2 EFNA3 MAPK14 SCNN1A RASSF4 MYRF

3.24e-0419710667265_UP
DrugDeltaline [6836-11-9]; Down 200; 7.8uM; MCF7; HT_HG-U133A

SIM2 CHST8 EFNA3 SEMA6D TBC1D22A VCPIP1

3.24e-0419710666026_DN
DrugAlfadolone acetate [23930-37-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A

CDHR2 ARHGAP26 CUL9 KCNIP1 ADAMTS12 EFNA3

3.24e-0419710666506_UP
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

NLGN1 TENM2 TNNI3K HSPA12A CNTNAP5 MAPK14 SEMA6D FAM168A RBFOX1 ARID5B IGSF9B PRKDC KDM4B

4.97e-0680110413EFO_0003888, EFO_0007052, MONDO_0002491
Diseaseage at menarche

PCSK2 CHAF1B TFAP2D KDM4C CHD2 TENM2 TNNI3K IGF2BP2 SEMA6D RBFOX1 KDM4B

8.25e-0659410411EFO_0004703
Diseasewaist-hip ratio

NID2 TFAP2D ATXN7L1 CUL9 RFX4 CFAP65 IGF2BP2 FAM168A TBC1D22A RBFOX1 ARID5B PIPSL PHLDB2 IQCK PAQR7

2.59e-05122610415EFO_0004343
Diseaseattention deficit hyperactivity disorder, intracranial volume measurement

SEMA6D RBFOX1

3.68e-0531042EFO_0003888, EFO_0004886
Diseaselevel of serum paraoxonase/arylesterase 1 in blood serum

PON1 PON2

3.68e-0531042OBA_2044998
Diseasecolorectal cancer

NID2 LAMA5 HSPA12A MRO RBFOX1 FADS2 DCLRE1A LRBA MYRF DCAF12

5.58e-0560410410MONDO_0005575
Diseasephosphatidylcholine measurement

KDM4C MS4A4A SCD RBFOX1 FADS2 MYRF SEZ6

6.81e-052841047EFO_0010226
Diseasephosphatidylcholine (18:0/20:2, 20:0/18:2) measurement

FADS2 MYRF

7.35e-0541042EFO_0800488
Diseasemedulloblastoma (is_marker_for)

KDM4C KDM4B

1.22e-0451042DOID:0050902 (is_marker_for)
Diseasenisinate (24:6n3) measurement

FADS2 MYRF

1.22e-0451042EFO_0800536
Diseaselevel of Phosphatidylcholine (16:0_20:1) in blood serum

FADS2 MYRF

1.22e-0451042OBA_2045073
Diseaselevel of Phosphatidylcholine (18:0_22:6) in blood serum

FADS2 MYRF

1.22e-0451042OBA_2045097
Diseaseperiodontitis

NLGN1 TENM2 TTC6 IGF2BP2 RBFOX1 KDM4B

1.43e-042231046EFO_0000649
Diseaseneurodegenerative disease (implicated_via_orthology)

MARS2 RASA1 PON1 PON2 SCNN1A

1.66e-041451045DOID:1289 (implicated_via_orthology)
Disease1-arachidonylglycerol (20:4) measurement

FADS2 MYRF

1.83e-0461042EFO_0800224
Disease1-arachidonoylglycerophosphocholine measurement

FADS2 MYRF

1.83e-0461042EFO_0021076
Disease1-linoleoylglycerophosphoethanolamine measurement

FADS2 MYRF

1.83e-0461042EFO_0021084
Diseaselevel of Phosphatidylethanolamine (O-16:1_20:4) in blood serum

FADS2 MYRF

1.83e-0461042OBA_2045145
Diseasearachidonoylcholine measurement

FADS2 MYRF

1.83e-0461042EFO_0800478
Diseaselysophosphatidylcholine 18:3 measurement

FADS2 MYRF

1.83e-0461042EFO_0021454
Disease1-docosapentaenoyl-GPC (22:5n3) measurement

FADS2 MYRF

1.83e-0461042EFO_0800298
Diseasegondoic acid measurement

FADS2 MYRF

1.83e-0461042EFO_0007975
Diseaselevel of Phosphatidylcholine (16:1_20:4) in blood serum

FADS2 MYRF

1.83e-0461042OBA_2045084
Diseasesmoking behavior

TENM2 TNNI3K IGF2BP2 SEMA6D FAM168A RBFOX1 ARID5B

2.11e-043411047EFO_0004318
Diseaseeicosapentaenoate (EPA; 20:5n3) measurement

FADS2 MYRF

2.55e-0471042EFO_0800616
Diseasearachidonate 20:4n6 measurement

FADS2 MYRF

2.55e-0471042EFO_0021063
Disease1-palmitoyl-2-docosahexaenoyl-GPC (16:0/22:6) measurement

FADS2 MYRF

2.55e-0471042EFO_0800391
Diseaselevel of Phosphatidylcholine (O-18:2_20:4) in blood serum

FADS2 MYRF

2.55e-0471042OBA_2045135
Disease1-eicosapentaenoyl-GPE (20:5) measurement

FADS2 MYRF

2.55e-0471042EFO_0800353
Diseasepneumococcal meningitis

MRO TBC1D22A

3.40e-0481042EFO_1001114
Diseasehydroxypalmitoyl sphingomyelin (d18:1/16:0(OH)) measurement

FADS2 MYRF

3.40e-0481042EFO_0800583
Diseasestearidonate 18:4n3 measurement

FADS2 MYRF

3.40e-0481042EFO_0021075
Disease1-stearoyl-2-docosahexaenoyl-GPC (18:0/22:6) measurement

FADS2 MYRF

3.40e-0481042EFO_0800392
Diseaselevel of Phosphatidylethanolamine (O-18:1_18:2) in blood serum

FADS2 MYRF

3.40e-0481042OBA_2045147
Diseaselevel of Phosphatidylethanolamine (O-18:2_20:4) in blood serum

FADS2 MYRF

3.40e-0481042OBA_2045151
Diseaseurate measurement, bone density

CHAF1B LAMA5 TENM2 GPR107 PEBP4 CNTNAP5 RBFOX1 ARID5B PRKDC

3.48e-046191049EFO_0003923, EFO_0004531
Disease1-arachidonoyl-GPE (20:4n6) measurement

FADS2 MYRF

4.36e-0491042EFO_0800248
Diseaselevel of Phosphatidylcholine (O-18:0_20:4) in blood serum

FADS2 MYRF

4.36e-0491042OBA_2045127
Diseaselevel of Phosphatidylcholine (O-18:1_18:2) in blood serum

FADS2 MYRF

4.36e-0491042OBA_2045129
Diseaselevel of Phosphatidylcholine (O-18:1_20:3) in blood serum

FADS2 MYRF

4.36e-0491042OBA_2045130
Disease1-stearoyl-2-arachidonoyl-GPC (18:0/20:4) measurement

FADS2 MYRF

4.36e-0491042EFO_0800271
Diseasecognitive function measurement

GLDN TFAP2D SZT2 KDM4C CHD2 MS4A4A TNNI3K CNTNAP5 EFNA3 SEMA6D TBC1D22A RBFOX1 IGSF9B KDM4B

5.10e-04143410414EFO_0008354
Diseasealopecia areata (is_marker_for)

KDM4C KDM4B

5.44e-04101042DOID:986 (is_marker_for)
Diseaselevel of Phosphatidylcholine (O-18:2_16:0) in blood serum

FADS2 MYRF

5.44e-04101042OBA_2045132
Diseaselevel of Phosphatidylethanolamine (O-18:1_20:4) in blood serum

FADS2 MYRF

5.44e-04101042OBA_2045148
Diseasecholesteryl ester 22:4 measurement

FADS2 MYRF

5.44e-04101042EFO_0021443
Diseasephosphatidylethanolamine ether measurement

FADS2 MYRF

5.44e-04101042EFO_0010229
Diseaselevel of Phosphatidylcholine (O-16:1_20:4) in blood serum

FADS2 MYRF

6.63e-04111042OBA_2045123
DiseaseTourette syndrome

OTUD1 PTPRU TENM2

7.39e-04501043EFO_0004895
DiseaseDrug habituation

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C0013170
DiseaseDrug abuse

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C0013146
DiseasePrescription Drug Abuse

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C4316881
DiseaseSubstance-Related Disorders

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C0236969
DiseaseDrug Use Disorders

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C0013222
DiseaseDrug Dependence

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C1510472
DiseaseSubstance Dependence

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C0038580
DiseaseSubstance Use Disorders

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

TENM2 HSPA12A SEMA6D XPO6

7.46e-041151044C0029231
DiseaseSubstance abuse problem

TENM2 HSPA12A SEMA6D XPO6

7.70e-041161044C0740858
Diseaselinoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement

FADS2 MYRF

7.94e-04121042EFO_0800500
Diseaselevel of Phosphatidylcholine (O-16:0_20:3) in blood serum

FADS2 MYRF

7.94e-04121042OBA_2045115
Diseasecholesteryl ester 20:2 measurement

FADS2 MYRF

7.94e-04121042EFO_0021440
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

FADS2 MYRF

9.36e-04131042EFO_0800547
Diseaselevel of Phosphatidylinositol (18:1_18:1) in blood serum

FADS2 MYRF

9.36e-04131042OBA_2045159
Diseaselevel of Sphingomyelin (d34:2) in blood serum

FADS2 MYRF

9.36e-04131042OBA_2045174
Diseasephosphatidylcholine ether measurement

FADS2 MYRF

9.36e-04131042EFO_0010227
DiseaseHyperlipoproteinemia Type IIb

PON1 PON2

9.36e-04131042C1704417
Diseasepolyp of colon

NID2 LAMA5 FADS2

1.03e-03561043MONDO_0021400
Diseaselevel of Phosphatidylcholine (18:1_20:2) in blood serum

FADS2 MYRF

1.09e-03141042OBA_2045102
Diseaselysophosphatidylcholine 22:5 measurement

FADS2 MYRF

1.09e-03141042EFO_0021462
Diseasediacylglycerol 38:4 measurement

FADS2 MYRF

1.09e-03141042EFO_0020066
Diseaseneutrophil count

DCPS ARHGAP26 GATA2 PIGV FCHO1 MSTO1 RBFOX1 VASH2 FADS2 PRKDC LRBA MYRF KDM4B

1.15e-03138210413EFO_0004833
Diseaseresponse to vaccine, cytokine measurement

TENM2 FRMD1 TENM1 DIP2C

1.21e-031311044EFO_0004645, EFO_0004873
Diseasecis/trans-18:2 fatty acid measurement, trans fatty acid measurement

FADS2 MYRF

1.25e-03151042EFO_0006821, EFO_0006824
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement

FADS2 MYRF

1.25e-03151042EFO_0800508
Diseaselevel of Phosphatidylcholine (O-18:1_20:4) in blood serum

FADS2 MYRF

1.25e-03151042OBA_2045131
Diseasephosphatidate measurement

FADS2 MYRF

1.25e-03151042EFO_0020047
Diseaserheumatoid arthritis

ARHGAP26 MAPK14 RBFOX1 ARID5B FADS2 C5 MYRF

1.27e-034621047EFO_0000685
Diseaselysophosphatidylcholine measurement

SCD FADS2 MYRF

1.38e-03621043EFO_0010224
DiseaseHyperlipoproteinemia Type IIa

PON1 PON2

1.43e-03161042C0745103
Diseasediacylglycerol 36:2 measurement

FADS2 MYRF

1.43e-03161042EFO_0010355
Diseasephosphatidylcholine 38:3 measurement

FADS2 MYRF

1.43e-03161042EFO_0010385
Diseasephosphatidylcholine 38:6 measurement

FADS2 MYRF

1.43e-03161042EFO_0010388
Diseaselevel of Phosphatidylcholine (18:0_20:3) in blood serum

FADS2 MYRF

1.43e-03161042OBA_2045093
Diseaseneutrophil percentage of leukocytes

DCPS GATA2 MS4A4A ARID5B FADS2 PRKDC KDM4B DCAF12

1.44e-036101048EFO_0007990
Diseasetriacylglycerol 56:9 measurement

CNTNAP5 FADS2

1.62e-03171042EFO_0010436
Diseaseamyloid-beta measurement

ARHGAP26 CHD2 TENM2 NBAS RBFOX1 PRKDC

1.64e-033551046EFO_0005194
DiseaseChild Behaviour Checklist assessment

PCSK2 PEBP4

1.81e-03181042EFO_0005661
Diseasetriacylglycerol 56:3 measurement

NLGN1 FADS2

1.81e-03181042EFO_0010430
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

FADS2 MYRF

1.81e-03181042OBA_2045155
Diseasediacylglycerol 36:3 measurement

FADS2 MYRF

1.81e-03181042EFO_0020062
Diseaselevel of Phosphatidylcholine (16:0_22:5) in blood serum

FADS2 MYRF

1.81e-03181042OBA_2045079
DiseaseHypercholesterolemia, Familial

PON1 PON2

1.81e-03181042C0020445
Diseasebreast cancer (is_implicated_in)

KDM4C PON1 MMP8 KDM4B

1.99e-031501044DOID:1612 (is_implicated_in)
DiseaseLipoidosis

SCD FADS2

2.02e-03191042C0023794
Diseaselevel of Phosphatidylethanolamine (18:0_20:4) in blood serum

FADS2 MYRF

2.02e-03191042OBA_2045140
DiseaseJuvenile Myelomonocytic Leukemia

ARHGAP26 GATA2

2.02e-03191042C0349639
Diseasediacylglycerol 38:5 measurement

FADS2 MYRF

2.02e-03191042EFO_0020067
Diseasediacylglycerol 38:3 measurement

FADS2 MYRF

2.02e-03191042EFO_0020065
Diseaseautism spectrum disorder (implicated_via_orthology)

CHD2 NLGN1 CNTNAP5 LRBA

2.09e-031521044DOID:0060041 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
HYVHSTPFGNYSFIC

TMEM62

171

Q0P6H9
FHPRSHFLYAYGNQI

CATSPERB

416

Q9H7T0
HCHYQGYAAEFPNSF

ADAM18

91

Q9Y3Q7
FPFGYVSNIHYHTLS

CHAF1B

336

Q13112
LNGSYTFIHLPYYFH

GLDN

356

Q6ZMI3
EPFADEYYGHLHVFT

FAM187A

156

A6NFU0
ITHPYEFDFYLCSHA

AGO3

741

Q9H9G7
PSYYHLHVHFTALGF

DCPS

271

Q96C86
HHYAAAYPSAYAPVS

CELF6

361

Q96J87
HLFGHYPAHDDFYLV

ATXN7L1

86

Q9ULK2
DASGHFLSYGLHYPI

ADAMTS12

61

P58397
YEFQHSHPAVTPDAY

TFAP2D

76

Q7Z6R9
EHFFHVFSGPRYYAF

MMP8

431

P22894
QHFSEEHYIFYFAGE

RASA1

546

P20936
GHFYNHKTSVFTPAY

RASSF4

171

Q9H2L5
SEYEHMQHFPGFAYI

RFX4

711

Q33E94
FHAIDYHYISSQGFP

GPR107

311

Q5VW38
FHGFSAEHYFPVSHF

IQCK

91

Q8N0W5
GVEFHYVYSHFLQFA

LBR

316

Q14739
AHSFRNHILGYFDYA

CACNA1F

896

O60840
YLPYNHQHEYFFLIG

FADS2

256

O95864
AFTEYVHAYFRGHSP

FCHO1

631

O14526
HYDAVFDHSYPNPEY

OTUD1

431

Q5VV17
HATSYAFHGLTPGYL

PTPRB

251

P23467
VFYGAAFYTNVLPHS

OR2T2

251

Q6IF00
FGSALAHFYYAIEPA

PAQR7

151

Q86WK9
PSYAPEFQFLHSAYA

FAM168A

46

Q92567
QALAHAYFAQYHDPD

MAPK14

301

Q16539
YFAGFEHHIPQYSLD

CFAP65

766

Q6ZU64
FPYLHYDATLPFHCS

MSTO1

316

Q9BUK6
PPAHSGFHRYQFFVY

PEBP4

141

Q96S96
TFPYGYHAGFNHGFN

KDM4B

271

O94953
ITFPYGYHAGFNHGF

KDM4C

271

Q9H3R0
FMVTFPYGYHAGFNH

KDM4D

271

Q6B0I6
TFPYGYHAGFNHGFN

KDM4E

271

B2RXH2
VPKFHYGTHYSTASF

LRBA

2296

P50851
LSHYHPEILQFFYAN

MRO

231

Q9BYG7
AIYLYCHQDFPGSSH

METTL15P1

216

P0C7V9
FHSFGYAARDFYHDL

HSPA12A

111

O43301
YHPFTTHSGYFSSLY

IGF2BP2

396

Q9Y6M1
FADGAPHYVAFYSNA

LAMA5

3196

O15230
HSNFGSPTYFYAFYH

NLGN1

516

Q8N2Q7
FSSHYPHGINTAIYH

NBAS

231

A2RRP1
AHHYNDFRFKTYAPV

PIP5K1A

131

Q99755
QFFPHGDASTYAHYL

KCNIP1

91

Q9NZI2
TPAHHYNAFRFKTYA

PIPSL

76

A2A3N6
YHVFSNLHPGTTYLF

PTPRU

551

Q92729
SATYLYLGHFHLDVF

PANX3

221

Q96QZ0
HAQAQYAYPGARFHI

NID2

946

Q14112
AVGPAHFYATNDHYF

PON2

171

Q15165
HFYATNDHYFSDPFL

PON2

176

Q15165
NVHHPSLFVAFYDYQ

PARP14

1776

Q460N5
SYVPAAAHDYSSGLF

GATA2

251

P23769
AHAGRYFEPHSYFPQ

FRMD1

201

Q8N878
HPYQYELNHFTPADA

EXOSC10

256

Q01780
DEYIYRHFFGHTFSP

CCPG1

726

Q9ULG6
HSYLDAYFVFPNGSA

CDHR2

1096

Q9BYE9
RYSHDFNFHINYGDL

HYOU1

486

Q9Y4L1
AFSLGYEFHAGHEYY

EFNA3

131

P52797
SFLSYLFHQHQLYGP

CHD2

521

O14647
FFPNAVYTHCYDSSG

DCAF12

416

Q5T6F0
ENGYDVYHSPQYHFL

FGF23

121

Q9GZV9
VPVFYVFHYLETGNH

C5

1016

P01031
HPTAANILFSAGYDY

CORO2A

141

Q92828
VHSAHNASGYFTIYG

DIP2C

1376

Q9Y2E4
GYYPGQLARLHFDHS

C1orf100

31

Q5SVJ3
NTFSLAFYSFHHPYC

MS4A4A

151

Q96JQ5
GLELATTFEHFYQHY

CUL9

1586

Q8IWT3
DHYAGLSKHFTFPVY

DCLRE1A

736

Q6PJP8
PGTYQRHYRNVFHAF

SLC25A35

36

Q3KQZ1
HFHHPMYGNCYTFND

SCNN1A

296

P37088
DSHHINPDSYYLFAD

JADE3

56

Q92613
YTEASYLHFPTFHAE

CNTNAP5

796

Q8WYK1
FFCFPHIHTIYYGEQ

OMD

351

Q99983
HFRTVPSNPHYFFYC

SZT2

1446

Q5T011
DSYGRVYAADPYHHA

RBFOX1

331

Q9NWB1
YLELFPAHLYFQAHG

PLEKHN1

116

Q494U1
FGCHPHFARYYSESQ

TATDN2

561

Q93075
EHFYGTNDHYFLDPY

PON1

176

P27169
PGFYHGHVSYLDFAK

HS2ST1

136

Q7LGA3
THYHPSNARFFTYGN

PITRM1

256

Q5JRX3
LAFLQGLFTFYHHGY

ARHGAP26

201

Q9UNA1
PLHHGFNYFYGISLT

STS

151

P08842
SYHYGHFPLDSHVFS

SIM2

441

Q14190
YHDTYPDFQVIIGFH

TENM1

2346

Q9UKZ4
GHHLQYFYSDLHNPT

TENM2

2316

Q9NT68
LNSFHYPDHSYKDQA

PHLDB2

986

Q86SQ0
NYTPADYGGLHHAAA

MTRF1

226

O75570
DFHHYGLASPIYTHF

DIS3

761

Q9Y2L1
FHGHYINGGFTVPFY

SMURF1

501

Q9HCE7
HGPYIFYKAFQFHLE

ARID5B

16

Q14865
SAFRDKFEHPNSYYH

CHST8

266

Q9H2A9
EHGYLYEHNFAFFPG

PIGV

76

Q9NUD9
DFPSLYDLGVHQYSH

ZNF341

511

Q9BYN7
THSHPACPLEFAYYF

ZSWIM9

121

Q86XI8
YSLAYFNAGNIYFHH

TTC6

381

Q86TZ1
FHHGQYYGYLSSSSP

IGSF9B

961

Q9UPX0
AGPGTFHFHYQAYLL

SEZ6

341

Q53EL9
SFKTYFSGNYFHHVV

VASH2

181

Q86V25
GFHNYHHSFPYDYSA

SCD

296

O00767
IFYVNAAPHIGHLYS

MARS2

51

Q96GW9
GIHPSLVADVHQYFY

VCPIP1

426

Q96JH7
TYQSEPDGFSHFHLY

TBC1D22A

441

Q8WUA7
SQGSVIHFSHGEYFY

PRKDC

1546

P78527
IHFSHGEYFYSLFSE

PRKDC

1551

P78527
LFKYTFHQPTHEGYF

XPO6

401

Q96QU8
PHFLHAIEYGNYVYF

SEMA6D

221

Q8NFY4
VFFTPLHIAAYYGHE

TNNI3K

166

Q59H18
GECGSYYNPHSDFHL

ZNF619

191

Q8N2I2
AQPATDYHFHFYRLC

MYRF

1136

Q9Y2G1
PFAEGLYHFYHNGLA

PCSK2

61

P16519