Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsulfate adenylyltransferase (ATP) activity

PAPSS2 PAPSS1

1.32e-052732GO:0004781
GeneOntologyMolecularFunctionsulfate adenylyltransferase activity

PAPSS2 PAPSS1

1.32e-052732GO:0004779
GeneOntologyMolecularFunctionadenylylsulfate kinase activity

PAPSS2 PAPSS1

1.32e-052732GO:0004020
GeneOntologyMolecularFunctionnucleoside diphosphate kinase activity

NME2P1 NME1 NME2

5.95e-0521733GO:0004550
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity, type I

BMPR1A BMPR1B

1.31e-045732GO:0005025
GeneOntologyMolecularFunctionligand-gated calcium channel activity

P2RX4 GRIN1 GRIN2B

1.96e-0431733GO:0099604
GeneOntologyMolecularFunctionBMP receptor activity

BMPR1A BMPR1B

3.64e-048732GO:0098821
GeneOntologyMolecularFunctionglutamate-gated calcium ion channel activity

GRIN1 GRIN2B

3.64e-048732GO:0022849
GeneOntologyMolecularFunctionNMDA glutamate receptor activity

GRIN1 GRIN2B

3.64e-048732GO:0004972
GeneOntologyMolecularFunctionphosphotransferase activity, phosphate group as acceptor

NME2P1 NME1 NME2

4.52e-0441733GO:0016776
GeneOntologyMolecularFunctionnucleobase-containing compound kinase activity

NME2P1 NME1 NME2

6.77e-0447733GO:0019205
GeneOntologyMolecularFunctionionotropic glutamate receptor binding

NETO2 GRIN1 GRIN2B

9.11e-0452733GO:0035255
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity

BMPR1A BMPR1B

1.00e-0313732GO:0005024
GeneOntologyMolecularFunctionglycine binding

GRIN1 GRIN2B

1.17e-0314732GO:0016594
GeneOntologyMolecularFunctionglutamate binding

GRIN1 GRIN2B

1.17e-0314732GO:0016595
GeneOntologyMolecularFunctionintermediate filament binding

NME1 NME2

1.34e-0315732GO:0019215
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIN1 GRIN2B

1.73e-0317732GO:0004970
GeneOntologyMolecularFunctioncarboxylic acid binding

ACACA CYP4F2 GRIN1 GRIN2B NME2

1.83e-03239735GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

ACACA CYP4F2 GRIN1 GRIN2B NME2

2.38e-03254735GO:0043177
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase activity

BMPR1A BMPR1B

2.40e-0320732GO:0004675
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

P2RX4 GRIN1 GRIN2B

2.82e-0377733GO:0005230
GeneOntologyMolecularFunctionBMP binding

BMPR1A BMPR1B

2.90e-0322732GO:0036122
GeneOntologyMolecularFunctionglutamate receptor binding

NETO2 GRIN1 GRIN2B

3.26e-0381733GO:0035254
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIN1 GRIN2B

3.45e-0324732GO:0099507
GeneOntologyMolecularFunctiontransition metal ion binding

ZCCHC9 FN1 P2RX4 LOXL2 WT1 CYP4F2 GRIN2B ZNF385C AGBL2 AGBL3 VAT1

3.78e-0311897311GO:0046914
GeneOntologyMolecularFunctionglutamate receptor activity

GRIN1 GRIN2B

4.36e-0327732GO:0008066
GeneOntologyBiologicalProcessUTP biosynthetic process

NME2P1 NME1 NME2

5.80e-0611693GO:0006228
GeneOntologyBiologicalProcessGTP biosynthetic process

NME2P1 NME1 NME2

1.00e-0513693GO:0006183
GeneOntologyBiologicalProcessUTP metabolic process

NME2P1 NME1 NME2

1.00e-0513693GO:0046051
GeneOntologyBiologicalProcess3'-phosphoadenosine 5'-phosphosulfate biosynthetic process

PAPSS2 PAPSS1

1.10e-052692GO:0050428
GeneOntologyBiologicalProcesspurine ribonucleoside bisphosphate biosynthetic process

PAPSS2 PAPSS1

1.10e-052692GO:0034036
GeneOntologyBiologicalProcesspurine ribonucleotide biosynthetic process

ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1

1.24e-05232697GO:0009152
GeneOntologyBiologicalProcessCTP biosynthetic process

NME2P1 NME1 NME2

1.58e-0515693GO:0006241
GeneOntologyBiologicalProcessribonucleotide biosynthetic process

ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1

1.86e-05247697GO:0009260
GeneOntologyBiologicalProcesspyrimidine ribonucleoside triphosphate biosynthetic process

NME2P1 NME1 NME2

1.94e-0516693GO:0009209
GeneOntologyBiologicalProcessribose phosphate biosynthetic process

ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1

2.17e-05253697GO:0046390
GeneOntologyBiologicalProcessCTP metabolic process

NME2P1 NME1 NME2

2.36e-0517693GO:0046036
GeneOntologyBiologicalProcesspyrimidine ribonucleoside triphosphate metabolic process

NME2P1 NME1 NME2

3.34e-0519693GO:0009208
GeneOntologyBiologicalProcesspyrimidine nucleoside triphosphate biosynthetic process

NME2P1 NME1 NME2

3.92e-0520693GO:0009148
GeneOntologyBiologicalProcesspurine nucleotide biosynthetic process

ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1

4.14e-05280697GO:0006164
GeneOntologyBiologicalProcesspurine-containing compound biosynthetic process

ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1

4.95e-05288697GO:0072522
GeneOntologyBiologicalProcessnucleoside bisphosphate biosynthetic process

ACACA ACLY PAPSS2 PAPSS1

5.18e-0561694GO:0033866
GeneOntologyBiologicalProcessribonucleoside bisphosphate biosynthetic process

ACACA ACLY PAPSS2 PAPSS1

5.18e-0561694GO:0034030
GeneOntologyBiologicalProcesspurine nucleoside bisphosphate biosynthetic process

ACACA ACLY PAPSS2 PAPSS1

5.18e-0561694GO:0034033
GeneOntologyBiologicalProcesssulfate assimilation

PAPSS2 PAPSS1

6.59e-054692GO:0000103
GeneOntologyBiologicalProcessmodulation of excitatory postsynaptic potential

NETO2 PCLO GRIN1 GRIN2B

6.66e-0565694GO:0098815
GeneOntologyBiologicalProcessexcitatory postsynaptic potential

P2RX4 NETO2 PCLO GRIN1 GRIN2B

7.49e-05130695GO:0060079
GeneOntologyBiologicalProcesspyrimidine ribonucleotide biosynthetic process

NME2P1 NME1 NME2

7.82e-0525693GO:0009220
GeneOntologyBiologicalProcesspyrimidine nucleoside triphosphate metabolic process

NME2P1 NME1 NME2

7.82e-0525693GO:0009147
GeneOntologyBiologicalProcessnucleotide biosynthetic process

ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1

9.41e-05319697GO:0009165
GeneOntologyBiologicalProcessnucleoside phosphate biosynthetic process

ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1

9.59e-05320697GO:1901293
GeneOntologyBiologicalProcessGTP metabolic process

NME2P1 NME1 NME2

1.23e-0429693GO:0046039
GeneOntologyBiologicalProcesschemical synaptic transmission, postsynaptic

P2RX4 NETO2 PCLO GRIN1 GRIN2B

1.34e-04147695GO:0099565
GeneOntologyBiologicalProcesscarbohydrate derivative biosynthetic process

TMTC1 BMPR1B ACACA ACLY NME2P1 NME1 NME2 PAPSS2 PAPSS1 CEMIP

1.60e-047366910GO:1901137
GeneOntologyBiologicalProcessprotein side chain deglutamylation

AGBL2 AGBL3

1.64e-046692GO:0035610
GeneOntologyBiologicalProcesspyrimidine nucleotide biosynthetic process

NME2P1 NME1 NME2

1.82e-0433693GO:0006221
GeneOntologyBiologicalProcesspyrimidine ribonucleotide metabolic process

NME2P1 NME1 NME2

1.99e-0434693GO:0009218
GeneOntologyBiologicalProcessdTMP biosynthetic process

NME1 NME2

2.29e-047692GO:0006231
GeneOntologyBiologicalProcesspyrimidine deoxyribonucleoside monophosphate biosynthetic process

NME1 NME2

2.29e-047692GO:0009177
GeneOntologyBiologicalProcessprotein deglutamylation

AGBL2 AGBL3

3.05e-048692GO:0035608
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

P2RX4 NETO2 PCLO GRIN1 GRIN2B

3.43e-04180695GO:0060078
GeneOntologyBiologicalProcesspyrimidine-containing compound biosynthetic process

NME2P1 NME1 NME2

4.02e-0443693GO:0072528
GeneOntologyBiologicalProcesspositive regulation of excitatory postsynaptic potential

NETO2 GRIN1 GRIN2B

4.02e-0443693GO:2000463
GeneOntologyBiologicalProcessregulation of axonogenesis

RGMA FN1 MCF2 MACF1 GRIN1

4.60e-04192695GO:0050770
GeneOntologyBiologicalProcessregulation of plasma membrane bounded cell projection organization

RGMA FN1 P2RX4 MCF2 MACF1 GRIN1 GRIN2B NME1 NME2 PLEKHM1

4.84e-048466910GO:0120035
GeneOntologyBiologicalProcessregulation of cell projection organization

RGMA FN1 P2RX4 MCF2 MACF1 GRIN1 GRIN2B NME1 NME2 PLEKHM1

5.66e-048636910GO:0031344
GeneOntologyBiologicalProcessaxonogenesis

RGMA BMPR1B HMCN2 FN1 MCF2 MACF1 GRIN1 CNP

5.88e-04566698GO:0007409
GeneOntologyBiologicalProcesspyrimidine deoxyribonucleotide biosynthetic process

NME1 NME2

5.95e-0411692GO:0009221
GeneOntologyBiologicalProcessdeoxyribonucleoside monophosphate biosynthetic process

NME1 NME2

7.12e-0412692GO:0009157
GeneOntologyBiologicalProcesspyrimidine nucleotide metabolic process

NME2P1 NME1 NME2

8.30e-0455693GO:0006220
GeneOntologyBiologicalProcessnegative regulation of protein localization to cell surface

TAX1BP3 ACTN2

8.40e-0413692GO:2000009
GeneOntologyBiologicalProcessdTMP metabolic process

NME1 NME2

9.78e-0414692GO:0046073
GeneOntologyCellularComponentdendritic branch

GRIN1 GRIN2B

2.50e-047732GO:0044307
GeneOntologyCellularComponentHFE-transferrin receptor complex

BMPR1A BMPR1B

3.32e-048732GO:1990712
GeneOntologyCellularComponentterminal bouton

P2RX4 PCLO GRIN1 GRIN2B

3.57e-0496734GO:0043195
GeneOntologyCellularComponentNMDA selective glutamate receptor complex

GRIN1 GRIN2B

4.26e-049732GO:0017146
GeneOntologyCellularComponentparallel fiber to Purkinje cell synapse

PCLO GRIN1 GRIN2B

4.56e-0443733GO:0098688
GeneOntologyCellularComponentsecretory granule lumen

DOCK2 FN1 ACLY ACTN2 NME2 VAT1

9.57e-04325736GO:0034774
GeneOntologyCellularComponentcytoplasmic vesicle lumen

DOCK2 FN1 ACLY ACTN2 NME2 VAT1

1.04e-03330736GO:0060205
GeneOntologyCellularComponentvesicle lumen

DOCK2 FN1 ACLY ACTN2 NME2 VAT1

1.07e-03332736GO:0031983
GeneOntologyCellularComponentpseudopodium

ACTN2 CNP

1.77e-0318732GO:0031143
MousePhenoabsence of NMDA-mediated synaptic currents

GRIN1 GRIN2B

1.41e-052532MP:0001901
DomainNDP_KINASES

NME2P1 NME1 NME2

4.73e-069733PS00469
DomainNDK

NME2P1 NME1 NME2

6.74e-0610733SM00562
DomainNDK

NME2P1 NME1 NME2

6.74e-0610733PF00334
DomainNucleoside_diP_kinase

NME2P1 NME1 NME2

1.23e-0512733IPR001564
DomainAPS_kinase

PAPSS2 PAPSS1

1.51e-052732IPR002891
DomainSulphate_adenylyltransferase

PAPSS2 PAPSS1

1.51e-052732IPR002650
DomainATP-Sase_PUA-like_dom

PAPSS2 PAPSS1

1.51e-052732IPR025980
DomainSulfurylase_cat_dom

PAPSS2 PAPSS1

1.51e-052732IPR024951
DomainATP-sulfurylase

PAPSS2 PAPSS1

1.51e-052732PF01747
DomainPUA_2

PAPSS2 PAPSS1

1.51e-052732PF14306
DomainG_patch

RBM10 RBM5 SON

9.59e-0523733SM00443
DomainG_patch_dom

RBM10 RBM5 SON

9.59e-0523733IPR000467
DomainG_PATCH

RBM10 RBM5 SON

9.59e-0523733PS50174
DomainG-patch

RBM10 RBM5 SON

9.59e-0523733PF01585
DomainNucleoside_diP_kinase_AS

NME1 NME2

1.50e-045732IPR023005
DomainSpectrin_repeat

MCF2 MACF1 ACTN2

1.95e-0429733IPR002017
DomainFAT

TMTC1 ATM

2.24e-046732PF02259
DomainPIK-rel_kinase_FAT

TMTC1 ATM

2.24e-046732IPR003151
DomainSpectrin/alpha-actinin

MCF2 MACF1 ACTN2

2.62e-0432733IPR018159
DomainSPEC

MCF2 MACF1 ACTN2

2.62e-0432733SM00150
DomainGS

BMPR1A BMPR1B

3.12e-047732SM00467
DomainGS_dom

BMPR1A BMPR1B

3.12e-047732IPR003605
DomainGS

BMPR1A BMPR1B

3.12e-047732PS51256
DomainTGF_beta_GS

BMPR1A BMPR1B

3.12e-047732PF08515
DomainActivin_recp

BMPR1A BMPR1B

6.64e-0410732IPR000472
Domain-

RBM10 RBM5

6.64e-04107324.10.1060.10
DomainActivin_recp

BMPR1A BMPR1B

6.64e-0410732PF01064
DomainTGFB_receptor

BMPR1A BMPR1B

9.70e-0412732IPR000333
DomainIontro_rcpt

GRIN1 GRIN2B

2.21e-0318732IPR001320
DomainLig_chan-Glu_bd

GRIN1 GRIN2B

2.21e-0318732PF10613
DomainIono_rcpt_met

GRIN1 GRIN2B

2.21e-0318732IPR001508
DomainGlu/Gly-bd

GRIN1 GRIN2B

2.21e-0318732IPR019594
DomainLig_chan-Glu_bd

GRIN1 GRIN2B

2.21e-0318732SM00918
DomainLig_chan

GRIN1 GRIN2B

2.21e-0318732PF00060
DomainPBPe

GRIN1 GRIN2B

2.21e-0318732SM00079
Domain-

ACACA ACLY

2.21e-03187323.30.470.20
DomainPUA-like_domain

PAPSS2 PAPSS1

2.47e-0319732IPR015947
Domainzf-RanBP

RBM10 RBM5

3.31e-0322732PF00641
DomainActinin_actin-bd_CS

MACF1 ACTN2

3.61e-0323732IPR001589
DomainZnF_RBZ

RBM10 RBM5

3.61e-0323732SM00547
DomainPeptidase_M14

AGBL2 AGBL3

3.61e-0323732PF00246
DomainSpectrin

MACF1 ACTN2

3.61e-0323732PF00435
DomainZF_RANBP2_2

RBM10 RBM5

3.61e-0323732PS50199
DomainPeptidase_M14

AGBL2 AGBL3

3.61e-0323732IPR000834
DomainACTININ_2

MACF1 ACTN2

3.61e-0323732PS00020
DomainACTININ_1

MACF1 ACTN2

3.61e-0323732PS00019
DomainZF_RANBP2_1

RBM10 RBM5

3.93e-0324732PS01358
DomainZnf_RanBP2

RBM10 RBM5

4.26e-0325732IPR001876
DomainATP_grasp_subdomain_2

ACACA ACLY

6.51e-0331732IPR013816
PathwayREACTOME_RAS_ACTIVATION_UPON_CA2_INFLUX_THROUGH_NMDA_RECEPTOR

GRIN1 ACTN2 GRIN2B

6.45e-0520563M17670
PathwayREACTOME_UNBLOCKING_OF_NMDA_RECEPTORS_GLUTAMATE_BINDING_AND_ACTIVATION

GRIN1 ACTN2 GRIN2B

7.51e-0521563M838
PathwayREACTOME_NEGATIVE_REGULATION_OF_NMDA_RECEPTOR_MEDIATED_NEURONAL_TRANSMISSION

GRIN1 ACTN2 GRIN2B

7.51e-0521563M27944
PathwayREACTOME_LONG_TERM_POTENTIATION

GRIN1 ACTN2 GRIN2B

9.94e-0523563M27949
PathwayKEGG_MEDICUS_REFERENCE_TRANSPORT_OF_CALCIUM

GRIN1 GRIN2B

1.54e-045562M47667
PathwayREACTOME_CREB1_PHOSPHORYLATION_THROUGH_NMDA_RECEPTOR_MEDIATED_ACTIVATION_OF_RAS_SIGNALING

GRIN1 ACTN2 GRIN2B

1.81e-0428563M837
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PDYN_TO_TRANSPORT_OF_CALCIUM

GRIN1 GRIN2B

2.30e-046562M47668
PathwayREACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS

PAPSS2 PAPSS1

2.30e-046562MM14679
PathwayREACTOME_TRANSPORT_AND_SYNTHESIS_OF_PAPS

PAPSS2 PAPSS1

2.30e-046562M27027
PathwayREACTOME_CHREBP_ACTIVATES_METABOLIC_GENE_EXPRESSION

ACACA ACLY

4.27e-048562M26991
PathwayKEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY

BMPR1A BMPR1B

5.48e-049562M47844
PathwayPID_BMP_PATHWAY

RGMA BMPR1A BMPR1B

6.11e-0442563M181
PathwayREACTOME_ASSEMBLY_AND_CELL_SURFACE_PRESENTATION_OF_NMDA_RECEPTORS

GRIN1 ACTN2 GRIN2B

7.01e-0444563M27934
PathwayREACTOME_RIBAVIRIN_ADME

NME1 NME2

8.33e-0411562M46429
PathwayWP_NOCGMPPKG_MEDIATED_NEUROPROTECTION

GRIN1 ACTN2 GRIN2B

8.51e-0447563M39531
PathwayWP_BONE_MORPHOGENIC_PROTEIN_SIGNALING_AND_REGULATION

BMPR1A BMPR1B

9.97e-0412562M39519
PathwayREACTOME_RIBAVIRIN_ADME

NME1 NME2

9.97e-0412562MM16638
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_LIGAND_GATED_CA2_CHANNEL

P2RX4 GRIN1

9.97e-0412562M47953
PathwayKEGG_SULFUR_METABOLISM

PAPSS2 PAPSS1

1.18e-0313562M18256
Pubmed

Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.

NME2P1 NME1 NME2

9.25e-0937438270257
Pubmed

Competitive binding of alpha-actinin and calmodulin to the NMDA receptor.

GRIN1 ACTN2 GRIN2B

9.22e-0857439009191
Pubmed

NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity.

GRIN1 ACTN2 GRIN2B

7.70e-07974316710293
Pubmed

Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma.

GRIN1 ACTN2 GRIN2B

2.01e-06127438615909
Pubmed

Developmental rearrangements of cortical glutamate-NMDA receptor binding sites in late human gestation.

GRIN1 ACTN2 GRIN2B

2.01e-06127438665664
Pubmed

Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle.

GRIN1 ACTN2 GRIN2B

2.01e-061274312815021
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

FN1 P2RX4 ACLY CAPN7 ZG16B NME2P1 ACTN2 MINPP1 NME1 NME2 CNP VAT1

2.56e-061070741223533145
Pubmed

Bmp in podocytes is essential for normal glomerular capillary formation.

BMPR1A BMPR1B WT1

3.31e-061474318272846
Pubmed

Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.

GRIN1 ACTN2 GRIN2B

3.31e-061474310373510
Pubmed

Conservation of notochord gene expression across chordates: insights from the Leprecan gene family.

ACLY PAPSS2 PAPSS1

3.31e-061474318798549
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

NETO2 MACF1 GRIN1 GRIN2B FAM171B FAM131B

4.12e-0619774636604605
Pubmed

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

GRIN1 ACTN2 GRIN2B

4.13e-061574314622581
Pubmed

Adjacent asparagines in the NR2-subunit of the NMDA receptor channel control the voltage-dependent block by extracellular Mg2+.

GRIN1 ACTN2 GRIN2B

4.13e-06157439481670
Pubmed

A comparison of the molecular bases for N-methyl-D-aspartate-receptor inhibition versus immobilizing activities of volatile aromatic anesthetics.

GRIN1 GRIN2B

4.47e-06274219095845
Pubmed

A member of a family of sulfate-activating enzymes causes murine brachymorphism.

PAPSS2 PAPSS1

4.47e-0627429671738
Pubmed

Glutamatergic signaling maintains the epithelial phenotype of proximal tubular cells.

GRIN1 GRIN2B

4.47e-06274221597037
Pubmed

Opposite roles of NMDA receptors in relapsing and primary progressive multiple sclerosis.

GRIN1 GRIN2B

4.47e-06274223840674
Pubmed

Reduced Nm23/Awd protein in tumour metastasis and aberrant Drosophila development.

NME1 NME2

4.47e-0627422509941
Pubmed

Genetic variants of the NMDA receptor influence cortical excitability and plasticity in humans.

GRIN1 GRIN2B

4.47e-06274221753020
Pubmed

The effect of NMDA-NR2B receptor subunit over-expression on olfactory memory task performance in the mouse.

GRIN1 GRIN2B

4.47e-06274215328026
Pubmed

RBM10 promotes transformation-associated processes in small cell lung cancer and is directly regulated by RBM5.

RBM10 RBM5

4.47e-06274228662214
Pubmed

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

BMPR1A BMPR1B

4.47e-06274215102710
Pubmed

Breast cancer expresses functional NMDA receptors.

GRIN1 GRIN2B

4.47e-06274219784770
Pubmed

Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23-->q24 byin situ hybridization and radiation hybrid map ping.

BMPR1A BMPR1B

4.47e-0627429730621
Pubmed

Scavenger Receptor Cysteine-Rich domains of Lysyl Oxidase-Like2 regulate endothelial ECM and angiogenesis through non-catalytic scaffolding mechanisms.

FN1 LOXL2

4.47e-06274231759052
Pubmed

Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues.

BMPR1A BMPR1B

4.47e-06274210850425
Pubmed

Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.

BMPR1A BMPR1B

4.47e-06274228357470
Pubmed

Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome.

NME1 NME2

4.47e-06274212200143
Pubmed

An association study of the N-methyl-D-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray.

GRIN1 GRIN2B

4.47e-06274215841096
Pubmed

Nme gene family evolutionary history reveals pre-metazoan origins and high conservation between humans and the sea anemone, Nematostella vectensis.

NME1 NME2

4.47e-06274221085602
Pubmed

An endoplasmic reticulum retention signal located in the extracellular amino-terminal domain of the NR2A subunit of N-Methyl-D-aspartate receptors.

GRIN1 GRIN2B

4.47e-06274219487695
Pubmed

Long-chain fatty acyl coenzyme A inhibits NME1/2 and regulates cancer metastasis.

NME1 NME2

4.47e-06274235259022
Pubmed

Characterization of the human nm23-H2 promoter region and localization of the microsatellite D17S396.

NME2P1 NME2

4.47e-0627427488060
Pubmed

A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential.

NME1 NME2

4.47e-0627428245015
Pubmed

Expression of cell surface NM23 proteins of human leukemia cell lines of various cellular lineage and differentiation stages.

NME1 NME2

4.47e-06274212007505
Pubmed

Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay.

RBM10 RBM5

4.47e-06274228586478
Pubmed

Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2).

BMPR1A BMPR1B

4.47e-06274215322331
Pubmed

Nucleotide binding to nucleoside diphosphate kinases: X-ray structure of human NDPK-A in complex with ADP and comparison to protein kinases.

NME1 NME2

4.47e-06274212972261
Pubmed

Overlapping cortical malformations in patients with pathogenic variants in GRIN1 and GRIN2B.

GRIN1 GRIN2B

4.47e-06274235393335
Pubmed

Nuclear localization of PAPS synthetase 1: a sulfate activation pathway in the nucleus of eukaryotic cells.

PAPSS2 PAPSS1

4.47e-06274210657990
Pubmed

Excitotoxic superoxide production and neuronal death require both ionotropic and non-ionotropic NMDA receptor signaling.

GRIN1 GRIN2B

4.47e-06274230504838
Pubmed

Influence of Genetic Variants of the N-Methyl-D-Aspartate Receptor on Emotion and Social Behavior in Adolescents.

GRIN1 GRIN2B

4.47e-06274226819771
Pubmed

Human 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 (PAPSS1) and PAPSS2: gene cloning, characterization and chromosomal localization.

PAPSS2 PAPSS1

4.47e-06274210679223
Pubmed

GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome.

GRIN1 GRIN2B

4.47e-06274226041915
Pubmed

Human T lymphocytes express N-methyl-D-aspartate receptors functionally active in controlling T cell activation.

GRIN1 GRIN2B

4.47e-06274216289038
Pubmed

Computationally Discovered Potentiating Role of Glycans on NMDA Receptors.

GRIN1 GRIN2B

4.47e-06274228378791
Pubmed

Redox regulation of neuronal migration in a Down Syndrome model.

GRIN1 GRIN2B

4.47e-06274212957649
Pubmed

Key amino acid residues within the third membrane domains of NR1 and NR2 subunits contribute to the regulation of the surface delivery of N-methyl-D-aspartate receptors.

GRIN1 GRIN2B

4.47e-06274222711533
Pubmed

Region-specific role for GluN2B-containing NMDA receptors in injury to Purkinje cells and CA1 neurons following global cerebral ischemia.

GRIN1 GRIN2B

4.47e-06274225450957
Pubmed

Mutations in orthologous genes in human spondyloepimetaphyseal dysplasia and the brachymorphic mouse.

PAPSS2 PAPSS1

4.47e-0627429771708
Pubmed

Association analysis of GRIN1 and GRIN2B polymorphisms and Parkinson's disease in a hospital-based case-control study.

GRIN1 GRIN2B

4.47e-06274220438806
Pubmed

BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.

BMPR1A BMPR1B

4.47e-06274231769494
Pubmed

Characterization and expression of human bifunctional 3'-phosphoadenosine 5'-phosphosulphate synthase isoforms.

PAPSS2 PAPSS1

4.47e-06274211931637
Pubmed

Role of WT1-ZNF224 interaction in the expression of apoptosis-regulating genes.

WT1 ZNF224

4.47e-06274223362234
Pubmed

Glioma-derived LRIG3 interacts with NETO2 in tumor-associated macrophages to modulate microenvironment and suppress tumor growth.

LRIG3 NETO2

4.47e-06274236639372
Pubmed

Polymorphisms, de novo lipogenesis, and plasma triglyceride response following fish oil supplementation.

ACACA ACLY

4.47e-06274223886516
Pubmed

BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.

BMPR1A BMPR1B

4.47e-06274232764110
Pubmed

Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits.

GRIN1 GRIN2B

4.47e-06274214573320
Pubmed

Specific activation of GluN1-N2B NMDA receptors underlies facilitation of cortical spreading depression in a genetic mouse model of migraine with reduced astrocytic glutamate clearance.

GRIN1 GRIN2B

4.47e-06274234111520
Pubmed

[BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell].

BMPR1A BMPR1B

4.47e-06274220673479
Pubmed

Biochemical and functional interaction between ZNF224 and ZNF255, two members of the Kruppel-like zinc-finger protein family and WT1 protein isoforms.

WT1 ZNF224

4.47e-06274220591825
Pubmed

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

WT1 ZNF224

4.47e-06274226320177
Pubmed

Possible protection by notoginsenoside R1 against glutamate neurotoxicity mediated by N-methyl-D-aspartate receptors composed of an NR1/NR2B subunit assembly.

GRIN1 GRIN2B

4.47e-06274219224577
Pubmed

Prevalence of serum N-methyl-D-aspartate receptor autoantibodies in refractory psychosis.

GRIN1 GRIN2B

4.47e-06274225431428
Pubmed

A Rare Variant Identified Within the GluN2B C-Terminus in a Patient with Autism Affects NMDA Receptor Surface Expression and Spine Density.

GRIN1 GRIN2B

4.47e-06274228283559
Pubmed

Inhibition of Wilms tumor 1 transactivation by bone marrow zinc finger 2, a novel transcriptional repressor.

WT1 ZNF224

4.47e-06274212239212
Pubmed

Ion permeation properties of the cloned mouse epsilon 2/zeta 1 NMDA receptor channel.

GRIN1 GRIN2B

4.47e-0627427531804
Pubmed

The Potential Functional Roles of NME1 Histidine Kinase Activity in Neuroblastoma Pathogenesis.

NME1 NME2

4.47e-06274232392889
Pubmed

Effects of cocaine-kindling on the expression of NMDA receptors and glutamate levels in mouse brain.

GRIN1 GRIN2B

4.47e-06274220927585
Pubmed

Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1.

MCF2 NME1

4.47e-06274218470881
Pubmed

Human PAPS synthase isoforms are dynamically regulated enzymes with access to nucleus and cytoplasm.

PAPSS2 PAPSS1

4.47e-06274222242175
Pubmed

Temperature dependence of NR1/NR2B NMDA receptor channels.

GRIN1 GRIN2B

4.47e-06274218068304
Pubmed

The effects of aging on N-methyl-D-aspartate receptor subunits in the synaptic membrane and relationships to long-term spatial memory.

GRIN1 GRIN2B

4.47e-06274219446010
Pubmed

GRIN1 mutation associated with intellectual disability alters NMDA receptor trafficking and function.

GRIN1 GRIN2B

4.47e-06274228228639
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

DOCK2 ACACA LMNB1 ACLY PCLO MACF1 NME1 PAPSS2 HYDIN VAT1

8.05e-06807741030575818
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

SASH1 LMNB1 PCLO MACF1 GRIN2B FAM131B

1.02e-0523174616452087
Pubmed

BMP-Responsive Protease HtrA1 Is Differentially Expressed in Astrocytes and Regulates Astrocytic Development and Injury Response.

BMPR1A FN1 CNP

1.03e-052074329483282
Pubmed

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.

GRIN1 ACTN2 GRIN2B

1.03e-052074316635246
Pubmed

Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.

ZNF223 ZNF224 ZNF225

1.03e-052074312743021
Pubmed

Oligodendroglial NMDA Receptors Regulate Glucose Import and Axonal Energy Metabolism.

GRIN1 CNP

1.34e-05374227292539
Pubmed

Studies on the subtype selectivity of CP-101,606: evidence for two classes of NR2B-selective NMDA receptor antagonists.

GRIN1 GRIN2B

1.34e-05374211897110
Pubmed

Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors.

GRIN1 GRIN2B

1.34e-05374210480938
Pubmed

Nm23/NDP kinases in human male germ cells: role in spermiogenesis and sperm motility?

NME1 NME2

1.34e-05374214499630
Pubmed

NMDA receptors mediate synaptic depression, but not spine loss in the dentate gyrus of adult amyloid Beta (Aβ) overexpressing mice.

GRIN1 GRIN2B

1.34e-05374230352630
Pubmed

Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line.

BMPR1A BMPR1B

1.34e-05374215897891
Pubmed

Disease-Associated Variants in GRIN1, GRIN2A and GRIN2B genes: Insights into NMDA Receptor Structure, Function, and Pathophysiology.

GRIN1 GRIN2B

1.34e-05374238836461
Pubmed

Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening.

GRIN1 GRIN2B

1.34e-05374237000222
Pubmed

The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function.

NME1 NME2

1.34e-05374219805292
Pubmed

Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.

BMPR1A BMPR1B

1.34e-05374226584636
Pubmed

Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy.

GRIN1 GRIN2B

1.34e-05374224101472
Pubmed

Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis.

BMPR1A BMPR1B

1.34e-05374225538007
Pubmed

Subunit-specific roles of glycine-binding domains in activation of NR1/NR3 N-methyl-D-aspartate receptors.

GRIN1 GRIN2B

1.34e-05374217047094
Pubmed

Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling.

BMPR1A BMPR1B

1.34e-05374224048844
Pubmed

Amyloid Beta-Mediated Changes in Synaptic Function and Spine Number of Neocortical Neurons Depend on NMDA Receptors.

GRIN1 GRIN2B

1.34e-05374234208315
Pubmed

Association of nucleoside diphosphate kinase nm23-H2 with human telomeres.

NME1 NME2

1.34e-0537429480811
Pubmed

Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.

BMPR1A BMPR1B

1.34e-05374215673568
Pubmed

Interactions of calmodulin and alpha-actinin with the NR1 subunit modulate Ca2+-dependent inactivation of NMDA receptors.

GRIN1 ACTN2

1.34e-0537429952395
Pubmed

NME proteins regulate class switch recombination.

NME1 NME2

1.34e-05374230411342
Pubmed

Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin.

ACACA ACLY

1.34e-05374221281598
Pubmed

Expression of bone morphogenetic protein receptors in the developing mouse metanephros.

BMPR1A BMPR1B

1.34e-05374211701996
CytobandEnsembl 112 genes in cytogenetic band chr17q21

ACLY ZNF385C NME1 NME2 PLEKHM1 CNP VAT1

1.17e-05473747chr17q21
Cytoband17q21

ACACA CNP VAT1

1.49e-046374317q21
Cytoband17q21.3

NME1 NME2

3.03e-041674217q21.3
CytobandEnsembl 112 genes in cytogenetic band chr9q34

HMCN2 SH2D3C FIBCD1 GRIN1

1.92e-03325744chr9q34
Cytoband19q13.2

ZNF223 ZNF224 ZNF225

2.41e-0316474319q13.2
Cytoband9q34.11

HMCN2 SH2D3C

3.35e-03537429q34.11
GeneFamilyG-patch domain containing|Minor histocompatibility antigens

RBM10 RBM5 SON

2.61e-0522483579
GeneFamilyType 1 receptor serine/threonine kinases

BMPR1A BMPR1B

1.44e-047482345
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN1 GRIN2B

1.44e-0474821201
GeneFamilyNME/NM23 family

NME1 NME2

2.46e-049482961
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RBM10 RBM5

1.40e-032148289
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1B KMT5B

3.67e-0334482487
CoexpressionHOOI_ST7_TARGETS_DN

TMTC1 FN1 KMT5B FAM131B CEMIP

1.88e-05115745M14801
CoexpressionGSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_DN

P2RX4 KMT5B RBM5 MACF1 PLEKHM1 SON

2.08e-05198746M7605
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D122|Adult / Lineage, Cell type, age group and donor

TMTC1 SASH1 NETO2 SH2D3C PLCXD3 ADGRL2

3.81e-07171736bd20e85d36fa9d7ddc8afef6a1dea75efc9ee1dc
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY PCLO TNRC6A FNDC3A PAPSS2 SON

7.27e-07191736fd01a206763dfb6d52cca67123571936b4a8e1a0
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ ACLY PCLO MACF1 PAPSS2 SON

8.21e-071957363e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ ACLY PCLO MACF1 PAPSS2 SON

8.21e-071957367796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SASH1 NETO2 SH2D3C PLCXD3 ADGRL2 VAT1

9.51e-072007363653002c805c314043e2a7b0c9980dfe952dc53e
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SASH1 SH2D3C PLCXD3 ADGRL2 PAPSS2 VAT1

9.51e-072007363767abc75176779198505ebc6967d55ce322d9fe
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SASH1 SH2D3C PLCXD3 ADGRL2 PAPSS2 VAT1

9.51e-07200736e0a003d2a5fd6adfcb817c9bc5dceb9c79e7491b
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ ACLY PCLO TNRC6A SON

7.89e-0616673566026988509e39e41274fa0de738383219e8ff30
ToppCellNasal_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ZNF668 FN1 NETO2 ADGRL2 CEMIP

9.38e-0617273558eaadf12366701103a0d1f133462c9495fedc30
ToppCellNasal_Brush-Epithelial-Basal_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ZNF668 FN1 NETO2 ADGRL2 CEMIP

9.38e-061727354483073469001770015526303772fd54906c5d68
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMTC1 BMPR1B ADGRL2 ALS2CL HYDIN

1.30e-0518473530fddbc9696476d4d7f08e53f84ea994a4ed873a
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TMTC1 BMPR1B ADGRL2 ALS2CL HYDIN

1.30e-0518473596926efa220f03d0787322c9519bb9e8f64f74d0
ToppCellfacs-Heart-LA-18m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY LOXL2 SH2D3C WT1 ADGRL2

1.40e-0518773587d4323a72e96ce35f9981faa92ded846a474384
ToppCellfacs-Heart-LA-18m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY LOXL2 SH2D3C WT1 ADGRL2

1.40e-05187735b0768a0102d533bc6c9efe56b7a9c18db7a374b7
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Adult / Lineage, Cell type, age group and donor

SASH1 NETO2 SH2D3C PLCXD3 ADGRL2

1.44e-05188735e5cad03f4a64147fe8174e7f614cf45233ffb9b7
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SASH1 NETO2 SH2D3C ADGRL2 VAT1

1.44e-05188735fe7143c36e4a883745862d3c3147cf751b440e46
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ ACLY PCLO PAPSS2 SON

1.44e-05188735a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.44e-051887353953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCell343B-Endothelial_cells-Endothelial-C_(Capillary_Aerocyte_)|343B / Donor, Lineage, Cell class and subclass (all cells)

SASH1 NETO2 SH2D3C ADGRL2 VAT1

1.44e-05188735cbf32b675a7cd0c808d5c9c22dfa7fa79fbe2437
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SASH1 NETO2 SH2D3C PLCXD3 ADGRL2

1.52e-051907350a351609a72fd638c84b2435782e312ee6a33aac
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY PCLO TNRC6A PAPSS2 SON

1.59e-051927351304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCelldroplet-Pancreas-Endocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY PCLO TNRC6A PAPSS2 SON

1.59e-051927354510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCellRV-10._Endothelium_II|RV / Chamber and Cluster_Paper

TMTC1 BMPR1B FN1 SASH1 PAPSS2

1.63e-0519373501c2df9206f1527c578e808978e58196c35e72f5
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGMA HMCN2 FN1 MACF1 FAM131B

1.63e-051937350256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY PCLO TNRC6A PAPSS2 SON

1.68e-0519473592b39a935e8c577eb1123d706d168fa13cf3344c
ToppCellLPS_only-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMTC1 SASH1 LOXL2 SH2D3C ADGRL2

1.68e-0519473558f069efdefa0366033764446b9d6ffd4a17807e
ToppCellLPS_only-Endothelial-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMTC1 SASH1 LOXL2 SH2D3C ADGRL2

1.68e-05194735bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCellAdult-Endothelial|Adult / Lineage, Cell type, age group and donor

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.68e-05194735963b3fbee0575af8379baa397ace65949eaf34f7
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

TMTC1 FN1 SASH1 SH2D3C MACF1

1.72e-05195735a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ ACLY PCLO GRIN1 PAPSS2

1.72e-05195735bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellproximal-Endothelial-Capillary_Aerocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NETO2 LOXL2 SH2D3C ADGRL2 VAT1

1.72e-05195735f1cbf82484f489fe7e0b5de6a49ea28d69f04e1a
ToppCellproximal-Endothelial-Capillary_Aerocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NETO2 LOXL2 SH2D3C ADGRL2 VAT1

1.72e-0519573513168c9632b58dd65ecb365df3832d95e7325919
ToppCellproximal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NETO2 LOXL2 SH2D3C ADGRL2 VAT1

1.72e-0519573536b2e754ed7ff138ac05fb51f4494e5339669828
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.72e-05195735094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ ACLY PCLO GRIN1 PAPSS2

1.72e-0519573558b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCellnucseq-Endothelial-Endothelial_Vascular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.76e-05196735686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TMTC1 SASH1 SH2D3C ADGRL2 PAPSS2

1.76e-05196735ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCellnucseq-Endothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.80e-05197735ebf9be068eaa658493fa7884fd19f34642922acb
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.85e-05198735a1ccbf0e653b2dd665c2254920eb9b37243cc0bd
ToppCellASK428-Endothelial|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

TMTC1 SASH1 PLCXD3 FAM171B ADGRL2

1.85e-05198735d69d0ff115298596173a4278897a65007a71f5df
ToppCellBronchial-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.89e-0519973536a230b80096455df26c2e2c8c05fd6b231508c5
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.89e-05199735d58edc5f74970bb26d844746184e4bae7c494d6b
ToppCellTracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SASH1 SH2D3C PLCXD3 ADGRL2 PAPSS2

1.89e-051997351621ce2968f3100e4c39e0ef8293232a5d76c614
ToppCellLPS_IL1RA-Endothelial-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SASH1 SH2D3C MACF1 ADGRL2 VAT1

1.94e-0520073572ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCelldistal-3-Endothelial-Capillary_Aerocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NETO2 SH2D3C ADGRL2 PAPSS2 VAT1

1.94e-05200735e12598a097dd9c4cbf9bb85bfa3057722ef73ad5
ToppCellBiopsy_IPF-Endothelial-Endothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

TMTC1 SASH1 SH2D3C PLCXD3 ADGRL2

1.94e-0520073539b4faad5700b3108f851f0df7fea3d298514465
ToppCellLPS_IL1RA-Endothelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SASH1 SH2D3C MACF1 ADGRL2 VAT1

1.94e-052007355c092b2ecc081b5d04476c56333c338cd89ab984
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SASH1 SH2D3C MACF1 ADGRL2 VAT1

1.94e-0520073579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCelldistal-Endothelial-Capillary_Aerocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NETO2 SH2D3C ADGRL2 PAPSS2 VAT1

1.94e-05200735d36236c7703b759309c8347f44900fc4bed377f0
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SASH1 PCLO PLCXD3 PAPSS2 CEMIP

1.94e-05200735891a80cbde575f81f3466217175f41e1d4f66d5e
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R|Neuronal / cells hierarchy compared to all cells using T-Statistic

SASH1 PCLO PLCXD3 PAPSS2 CEMIP

1.94e-05200735c761d1742653a83e69e4c03d6e10e5e53f28bebb
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SASH1 NETO2 SH2D3C PLCXD3 ADGRL2

1.94e-05200735105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellNeuronal-Excitatory-eC(RORB)-eC_2-C1R--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SASH1 PCLO PLCXD3 PAPSS2 CEMIP

1.94e-05200735dcbc91ed3351bafd72cf71d7025cbbdc8361d9b9
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RBM10 MCF2 PLCXD3 HYDIN

8.98e-05143734ce045ec7c311a1797ae562bec114f9e90604d063
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-NP|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TMTC1 NETO2 LOXL2 PLCXD3

1.08e-041507342ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

BSND TAX1BP3 PAPSS1 VAT1

1.32e-041587344d997efc36fd8946775fe74dd9ac9ccd5ade64ff
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SGCZ GRIN2B HYDIN

1.39e-04160734c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A2 SGCZ GRIN2B HYDIN

1.39e-0416073425c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 FN1 WT1 MCF2

1.42e-041617341b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

SASH1 SH2D3C PLCXD3 ADGRL2

1.63e-041677345af9127bae05768a5164d5708a4ad37edca99324
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FN1 MACF1 PLCXD3 ACTN2

1.75e-041707347fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA FIBCD1 PLCXD3 ACTN2

1.75e-0417073484d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RGMA FIBCD1 PLCXD3 ACTN2

1.83e-04172734cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 FN1 WT1 MCF2

1.83e-0417273408a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell343B-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC6A16 LOXL2 ZNF225 ADGRL2

1.83e-04172734eb199c279fe8a2551121db37e9556893197d33ff
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 LMNB1 SH2D3C ALS2CL

1.83e-0417273494093d356b0252b440deda4e1b0ac332b31513f6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 FN1 WT1 MCF2

1.83e-04172734553701349444eb366df3c11f54bb093434f153c6
ToppCell343B-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

SLC6A16 LOXL2 ZNF225 ADGRL2

1.83e-04172734709c6b77a7a52b873eefb6caca28a41291d384af
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RGMA ACACA P2RX4 APBB3

1.95e-041757341d8aab491dcc27ea5dbfb6462d18ee280b21a05e
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RGMA ACACA P2RX4 APBB3

1.95e-04175734427a7ee92fe16a90625946492062d37aa0f7235b
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGCZ GRIN2B HYDIN CNP

1.95e-04175734887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BMPR1A ALS2CL CNP TECPR1

2.00e-04176734218a072882d387adbbad6916d7214099c7354465
ToppCelldroplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMPR1B RMI2 ALS2CL PLEKHM1

2.00e-04176734533d544852038c0612aacf87f4b1c88ff7aace82
ToppCell390C-Endothelial_cells-Endothelial-E-|390C / Donor, Lineage, Cell class and subclass (all cells)

TMTC1 SH2D3C ADGRL2 ALS2CL

2.08e-04178734804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC1 FN1 SASH1 SH2D3C

2.08e-04178734375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCell390C-Endothelial_cells-Endothelial-E|390C / Donor, Lineage, Cell class and subclass (all cells)

TMTC1 SH2D3C ADGRL2 ALS2CL

2.08e-04178734ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCellIIH-matDC|IIH / Condition, Cell_class and T cell subcluster

TMTC1 LOXL2 ADGRL2 CEMIP

2.13e-041797345999c85ce3bab5309ff1ed154be7e32b037750b1
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLCXD3 GRIN1 GRIN2B FAM131B

2.13e-04179734228d12ed1c8dc92aefbcea4aaf7d108783c22be0
ToppCellIIH-matDC-|IIH / Condition, Cell_class and T cell subcluster

TMTC1 LOXL2 ADGRL2 CEMIP

2.13e-0417973446074b2781ed79e2979428b3ec81504621d3903c
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 LOXL2 RMI2 WT1

2.17e-04180734f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

SASH1 SH2D3C PLCXD3 ADGRL2

2.17e-04180734b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LOXL2 SH2D3C ADGRL2 VAT1

2.17e-04180734544fb373a3346186ec60afe2cfcf141bb04a1eed
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

SASH1 LOXL2 SH2D3C ADGRL2

2.22e-0418173461608123959483ff60f07d8467996853c4371b6a
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRIG3 SGCZ HMCN2 PLCXD3

2.22e-04181734af92b8b7f455210dab502ef6964f3a0162180759
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 LOXL2 RMI2 WT1

2.22e-04181734c7f5aedcb74c21fb587a95a16d700e2a38a380ee
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SASH1 SH2D3C PLCXD3 ADGRL2

2.22e-04181734c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCellfacs-Kidney-nan-24m-Mesenchymal-kidney_interstitial_fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 LOXL2 RMI2 WT1

2.22e-041817340ec9621a078d004bbd25a587757d24b5cf162959
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BMPR1B GRIN2B ADGRL2 PAPSS2

2.27e-04182734f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D175|Adult / Lineage, Cell type, age group and donor

SASH1 SH2D3C PLCXD3 ADGRL2

2.27e-041827348b4a07ebd7a133a33ef333cfa29d12c4f3d4d9ac
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SASH1 SH2D3C PLCXD3 ADGRL2

2.27e-04182734a20017b6a4f9a6a29e090e4dbd7c02ed1495bd50
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK2 RMI2 NME1 CNP

2.32e-04183734956ff95aef9c5521b6a3ba7ac6df0aad242c1c35
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SASH1 SH2D3C PLCXD3 FAM171B

2.32e-041837342d0d3b486498a7903fa9a1f48b189291da49c430
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SASH1 SH2D3C ADGRL2 VAT1

2.32e-04183734e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

TMTC1 SASH1 PLCXD3 ADGRL2

2.32e-0418373446be9f96755c7b65aeac061d95d15abeb6466034
ToppCellMesenchymal_cells-Chondrocytes|World / Lineage and Cell class

FN1 ZNF385C PAPSS2 CEMIP

2.36e-041847341e03f9f08de5ad4d45388a95afad9f23ff0d0e28
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

SASH1 LOXL2 SH2D3C ADGRL2

2.36e-041847345f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TMTC1 SASH1 PLCXD3 ADGRL2

2.41e-04185734f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellControl-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

SASH1 SH2D3C PLCXD3 ADGRL2

2.41e-04185734a28187c2fd23564314b35759479ff2ca21f61485
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

TMTC1 SASH1 SH2D3C ADGRL2

2.46e-04186734c6075fe84226b370c5139066793844ad33ae2db1
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SASH1 SH2D3C ADGRL2 VAT1

2.51e-04187734ea9d34bcd3bd1f36745846309ede349773de501a
Drug3'-AMP

P2RX4 ACLY APBB3 PAPSS2 PAPSS1 CNP

1.26e-0772746CID000041211
DrugEstradiol-17 beta [50-28-2]; Down 200; 14.6uM; HL60; HT_HG-U133A

FN1 SASH1 LMNB1 ACLY RBM5 ZNF223 CNP VAT1

2.62e-071987481299_DN
DrugAC1Q4Q30

ACACA WT1 GBA2

2.73e-069743CID000185818
DrugDiethylcarbamazine citrate [1642-54-2]; Up 200; 10.2uM; HL60; HT_HG-U133A

SLC17A2 ZNF668 FN1 RBM5 MACF1 ADGRL2 PAPSS2

3.36e-061957472394_UP
Drugadenosine 5'-phosphoselenate

PAPSS2 PAPSS1

1.04e-052742CID000440758
Drugbeta-methylene-APS

PAPSS2 PAPSS1

1.04e-052742CID000129324
DrugNifurthiazole

FN1 ACLY FNDC3A

1.46e-0515743CID003607071
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

ZNF668 SETD1B LMNB1 KMT5B WT1 ATM

2.13e-051737464565_DN
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HG-U133A

ACACA LMNB1 RBM10 WT1 RBM5 SON

2.84e-051827461891_DN
DrugU-320

FN1 FNDC3A

3.12e-053742CID000077162
DrugAlbendazole [54965-21-8]; Down 200; 15uM; HL60; HG-U133A

FN1 ACLY RBM10 CAPN7 ACTN2 ATM

4.06e-051947461547_DN
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

SLC17A2 LOXL2 MCF2 GRIN1 UBXN1 CEMIP

4.67e-051997463759_UP
Drugdigalactosyldiacylglycerol (DGDG

LMNB1 PAPSS2 PAPSS1

5.57e-0523743CID000447899
Drugn-propylbenzene

GRIN1 GRIN2B

6.23e-054742ctd:C024268
DrugSF-6,5

FN1 FNDC3A

6.23e-054742CID000126860
Diseaseteratoma (is_implicated_in)

NME1 NME2

5.52e-055702DOID:3307 (is_implicated_in)
Diseasenucleoside diphosphate kinase B measurement

NME1 NME2

1.16e-047702EFO_0020615
Diseaseplacental insufficiency (biomarker_via_orthology)

GRIN1 GRIN2B

1.54e-048702DOID:3891 (biomarker_via_orthology)
Diseasecognitive disorder (biomarker_via_orthology)

GRIN1 GRIN2B

1.54e-048702DOID:1561 (biomarker_via_orthology)
DiseaseGastric Adenocarcinoma

BMPR1A BMPR1B ATM

1.69e-0445703C0278701
Diseaseresponse to hydrochlorothiazide, diastolic blood pressure change measurement

SGCZ PLCXD3

2.47e-0410702EFO_0005202, EFO_0006945
Diseaseopioid dependence

RGMA SGCZ BMPR1B GRIN2B ADGRL2

2.54e-04237705EFO_0005611
Diseasevascular dementia (is_marker_for)

GRIN1 GRIN2B

3.01e-0411702DOID:8725 (is_marker_for)
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

BMPR1A BMPR1B

4.25e-0413702DOID:0050787 (implicated_via_orthology)
Diseasealcohol use disorder (is_implicated_in)

GRIN1 GRIN2B

6.52e-0416702DOID:1574 (is_implicated_in)
DiseaseEye Abnormalities

BMPR1A BMPR1B

7.37e-0417702C0015393
Diseasenicotine dependence symptom count, depressive symptom measurement

RGMA PCLO GRIN2B

7.64e-0475703EFO_0007006, EFO_0009262
Diseasemuscular dystrophy (implicated_via_orthology)

SGCZ LMNB1

1.13e-0321702DOID:9884 (implicated_via_orthology)
Diseasesciatic neuropathy (biomarker_via_orthology)

RGMA GRIN1 GRIN2B

1.70e-0399703DOID:11446 (biomarker_via_orthology)
Diseasevisuospatial function measurement

RGMA GRIN2B

1.74e-0326702EFO_0803533
DiseaseAdenoid Cystic Carcinoma

NETO2 ATM SON

1.75e-03100703C0010606
Diseasetransforming growth factor beta measurement

RGMA ADGRL2

1.87e-0327702EFO_0004818
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

GRIN2B ADGRL2

2.02e-0328702DOID:1094 (implicated_via_orthology)
DiseaseBarrett's esophagus

HMCN2 GRIN2B

2.02e-0328702EFO_0000280
Diseaseurinary bladder cancer (is_marker_for)

FN1 NME1 NME2

2.13e-03107703DOID:11054 (is_marker_for)
DiseaseEpileptic encephalopathy

GRIN1 GRIN2B

2.31e-0330702C0543888

Protein segments in the cluster

PeptideGeneStartEntry
TGAKHRWMMEGQRGA

ZNF385C

241

Q66K41
MWQAGQRHGPGVMVT

ALS2CL

486

Q60I27
GTGRVVMWKMGIRNS

AGBL3

516

Q8NEM8
MAQMGVGEGKSIGEW

ATG4A

131

Q8WYN0
EIVDGNVKMTLGMIW

ACTN2

121

P35609
LPGGNEIGMVAWKMT

ACACA

1651

Q13085
GIKWPQTQRGMMVER

ADGRL2

476

O95490
MVKQIGKGRYGEVWM

BMPR1B

206

O00238
ESGNVGTEMMDNRIW

CEMIP

841

Q8WUJ3
SIGQWQKVMEAMGVL

ANO8

801

Q9HCE9
IGSRMLQAMGWKEGS

RBM10

861

P98175
MAVEGGIMGIQVNWD

P2RX4

246

Q99571
MVWEGLNVVKTGRVM

NME2

76

P22392
IKMVMESGDWLVGGD

PAPSS2

356

O95340
KACQMIMGSWNPVGV

LEXM

341

Q3ZCV2
MQRNGVTKLMDGAFW

LRIG3

246

Q6UXM1
AGGWMLKMTQTQEQD

HMCN2

2411

Q8NDA2
MKWLGESKNMVVNGR

KMT5B

1

Q4FZB7
MGGWEMIRKIGDTSV

LMNB1

466

P20700
GMVCGQNWGIVEAMV

LOXL2

461

Q9Y4K0
TGKLMEGMQVLEWNG

PCLO

4546

Q9Y6V0
SSRMSWGIQQALVGM

OR3A4P

136

P47883
MVLMQDKGSSQQWPG

SLC10A3

1

P09131
IGNKMLQAMGWREGS

RBM5

746

P52756
AMGQGRVAHMIEWQG

FAM131B

76

Q86XD5
TVMVRVGGGWMALDE

MACF1

7166

Q9UPN3
IKMVMEQGDWLIGGD

PAPSS1

366

O43252
WLENSGVSEVNGMMK

ATM

2491

Q13315
DGAWGEGQNMLMILK

APBB3

161

O95704
MMNTGDVGARFKWDI

HYDIN

4551

Q4G0P3
GSVMVIGGIIWSMCQ

BSND

41

Q8WZ55
KGDSGGQGLWVTMKM

DOCK2

371

Q92608
GQGLWVTMKMLVGDI

DOCK2

376

Q92608
TGMMTEAEGEKWGLV

CAPN7

441

Q9Y6W3
AWDMPRIMFGAKGQV

GBA2

411

Q9HCG7
IGEKWDRQGENGQMM

FN1

2351

P02751
VEMAEGSNGNKWEMI

FNDC3A

601

Q9Y2H6
MVRQVGKGRYGEVWM

BMPR1A

236

P36894
EGTGRVVMWRMGILN

AGBL2

611

Q5U5Z8
GNGRWMLTLAKNMEV

CNP

376

P09543
WGHQGMVNPTEEGMR

CYP4F2

61

P78329
LGKMIMQGGFSVWIG

MCF2

691

P10911
MVNDRWKTMGGAAQL

FIBCD1

1

Q8N539
MNTGAWVNHGRGMVK

FAM171B

296

Q6P995
MKLGTVERRGAMGIW

PLEKHM1

536

Q9Y4G2
AAVWMQGRVVMADRG

RMI2

56

Q96E14
SMRQGGMGVWKIIAP

SLC6A16

166

Q9GZN6
MVWEGLNVVKTGRVM

NME1

76

P15531
MVWEGLNVVKTGRVM

NME2P1

61

O60361
MQVDMSHVLGGQWGG

SETD1B

756

Q9UPS6
NDVMLKTGIGVIRMW

NETO2

261

Q8NC67
WILKVMNFTVDGMGN

SGCZ

56

Q96LD1
ERLVVTGRAGWMGMG

RGMA

6

Q96B86
VWGMQTRAVQGMLDF

ACLY

501

P53396
MMQWVRTQKPGESGI

PLCXD3

276

Q63HM9
MGAQGAQESIKAMWR

ZG16B

1

Q96DA0
WMMDIATQREGNSGG

ZNF223

66

Q9UK11
SGGVMATQWQVVGMT

ZNF668

466

Q96K58
WMNMGGIQHIKGKYV

TMTC1

826

Q8IUR5
WMDGQLVEKGRQDMR

MINPP1

141

Q9UNW1
TMVNVGMNDQVWGIG

TECPR1

336

Q7Z6L1
RTVQGMAQGMAWTGQ

SLC17A2

151

O00624
LQIGDKIMQVNGWDM

TAX1BP3

71

O14907
MTWNQMNLGATLKGV

WT1

236

P19544
MGTWMGLLNNKVGTF

SASH1

591

O94885
VGTNMGWADAMAKVL

RRP15

86

Q9Y3B9
LTGNQGIEAAMDWLM

UBXN1

26

Q04323
WMMETATQREGNLGG

ZNF225

66

Q9UK10
GDRVMVLNRSGMWQE

VAT1

131

Q99536
NSERMVTVGRWAKGM

ZCCHC9

231

Q8N567
GVTKEMQTLMGVRWG

SH2D3C

606

Q8N5H7
WMMKTAIQREGNSGD

ZNF224

66

Q9NZL3
VLMRKMGWREGEGLG

SON

2311

P18583
ERGMMKGGNKQEEAW

TNRC6A

1186

Q8NDV7
NGTWNGMIGEVVMKR

GRIN2B

491

Q13224
KEWNGMMGELLSGQA

GRIN1

496

Q05586