Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

1.07e-0431202GO:0018858
GeneOntologyMolecularFunctionhistone binding

VPS72 NASP CHD3 WRAP53 HINFP MCM3AP SMARCC1 SMARCC2

2.02e-042651208GO:0042393
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

2.13e-0441202GO:0102391
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair

VPS72 WRAP53 ARID1A SMARCC1 SMARCC2 TIMELESS

1.69e-05951176GO:2000781
GeneOntologyBiologicalProcessprotein localization to cell surface

ANK2 ABCA7 WASH6P WASH3P RAB11FIP5

8.69e-05791175GO:0034394
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

PSEN1 VPS72 KDM5C IRF1 CHD3 ZNF318 MAGEE1 ARID1A HINFP PARP10 WWC2 SMTNL1 AHRR ZC3H4 SKOR2 PLCB1 SMARCC2 TIMELESS MAGEC2 FOXG1

1.12e-04139911720GO:0045892
GeneOntologyBiologicalProcessmyoblast differentiation

ARID1A HINFP PLCB1 SMARCC1 SMARCC2 SDC1

1.26e-041361176GO:0045445
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

PSEN1 VPS72 KDM5C IRF1 CHD3 ZNF318 MAGEE1 ARID1A HINFP PARP10 WWC2 SMTNL1 AHRR ZC3H4 SKOR2 PLCB1 SMARCC2 TIMELESS MAGEC2 FOXG1

1.28e-04141311720GO:1902679
GeneOntologyBiologicalProcessoocyte maturation

WASH6P WASH3P PLCB1 WEE2

1.45e-04471174GO:0001556
GeneOntologyBiologicalProcesspositive regulation of DNA repair

VPS72 WRAP53 ARID1A SMARCC1 SMARCC2 TIMELESS

1.66e-041431176GO:0045739
GeneOntologyBiologicalProcessregulation of double-strand break repair

VPS72 WRAP53 ARID1A SMARCC1 SMARCC2 TIMELESS

1.86e-041461176GO:2000779
GeneOntologyBiologicalProcessregulation of fertilization

RNASE10 PLCB1 WEE2

1.89e-04201173GO:0080154
GeneOntologyBiologicalProcessregulation of protein localization to cell surface

ABCA7 WASH6P WASH3P RAB11FIP5

2.00e-04511174GO:2000008
GeneOntologyBiologicalProcesspositive regulation of myoblast differentiation

ARID1A PLCB1 SMARCC1 SMARCC2

2.50e-04541174GO:0045663
GeneOntologyBiologicalProcessoocyte development

WASH6P WASH3P KMT2D PLCB1 WEE2

2.52e-04991175GO:0048599
GeneOntologyBiologicalProcessnucleosome disassembly

ARID1A SMARCC1 SMARCC2

2.53e-04221173GO:0006337
GeneOntologyBiologicalProcessoogenesis

WASH6P WASH3P KMT2D PLCB1 WEE2 NOBOX

2.66e-041561176GO:0048477
GeneOntologyBiologicalProcessoocyte differentiation

WASH6P WASH3P KMT2D PLCB1 WEE2

3.03e-041031175GO:0009994
GeneOntologyCellularComponentcostamere

ANK2 ANK3 AHNAK AHNAK2

6.75e-06221194GO:0043034
GeneOntologyCellularComponentnpBAF complex

ARID1A SMARCC1 SMARCC2

6.25e-05141193GO:0071564
GeneOntologyCellularComponentbrahma complex

ARID1A SMARCC1 SMARCC2

6.25e-05141193GO:0035060
GeneOntologyCellularComponentT-tubule

ANK2 ANK3 STAC AHNAK AHNAK2

8.85e-05791195GO:0030315
GeneOntologyCellularComponentnBAF complex

ARID1A SMARCC1 SMARCC2

9.54e-05161193GO:0071565
GeneOntologyCellularComponentchromatin

TFEB VPS72 KDM5C MYT1 NASP IRF1 RFX6 CHD3 ARID1A FANCE AHRR CSRNP2 ANKRD11 PLCB1 SMARCC1 SMARCC2 DMRTA2 TIMELESS FOXG1 NOBOX

2.51e-04148011920GO:0000785
GeneOntologyCellularComponentSWI/SNF complex

ARID1A SMARCC1 SMARCC2

6.53e-04301193GO:0016514
GeneOntologyCellularComponentsarcolemma

PSEN1 ANK2 ANK3 STAC AHNAK AHNAK2

7.73e-041901196GO:0042383
GeneOntologyCellularComponentcell cortex

CTTNBP2 PSEN1 AKAP12 BFSP1 WASH6P WASH3P BSN SCIN

1.29e-033711198GO:0005938
GeneOntologyCellularComponentearly endosome membrane

PSEN1 ABCA7 WASH6P WASH3P RAB11FIP5 SNX2

1.36e-032121196GO:0031901
GeneOntologyCellularComponentbBAF complex

ARID1A SMARCC2

1.40e-03101192GO:0140092
GeneOntologyCellularComponentearly endosome

PSEN1 ANK2 ABCA7 TBC1D16 WASH6P WASH3P RAB11FIP5 FGD5 SNX2

1.74e-034811199GO:0005769
DomainSMARCC_C

SMARCC1 SMARCC2

3.82e-0521162IPR032451
DomainSMARCC_N

SMARCC1 SMARCC2

3.82e-0521162IPR032450
DomainSWIRM-assoc

SMARCC1 SMARCC2

3.82e-0521162IPR032448
DomainSWIRM-assoc_2

SMARCC1 SMARCC2

3.82e-0521162PF16496
DomainSWIRM-assoc_1

SMARCC1 SMARCC2

3.82e-0521162PF16495
DomainSWIRM-assoc_3

SMARCC1 SMARCC2

3.82e-0521162PF16498
DomainZnf_FYVE_PHD

KDM5C CHD3 KMT2D FGD5 BSN SP140

3.13e-041471166IPR011011
DomainSWIRM

SMARCC1 SMARCC2

5.64e-0461162PS50934
DomainSWIRM

SMARCC1 SMARCC2

5.64e-0461162PF04433
DomainSWIRM

SMARCC1 SMARCC2

5.64e-0461162IPR007526
DomainChromo/shadow_dom

CHD3 SMARCC1 SMARCC2

1.11e-03331163IPR000953
DomainCHROMO

CHD3 SMARCC1 SMARCC2

1.11e-03331163SM00298
DomainPHD

KDM5C CHD3 KMT2D SP140

1.22e-03751164PF00628
DomainZU5

ANK2 ANK3

1.34e-0391162SM00218
DomainZnf_PHD-finger

KDM5C CHD3 KMT2D SP140

1.48e-03791164IPR019787
DomainZU5

ANK2 ANK3

1.67e-03101162PS51145
DomainPHD

KDM5C CHD3 KMT2D SP140

2.30e-03891164SM00249
Domain-

SKOR2 SP140

2.42e-031211623.10.390.10
DomainZU5

ANK2 ANK3

2.42e-03121162PF00791
DomainZU5_dom

ANK2 ANK3

2.42e-03121162IPR000906
DomainSAND_dom-like

SKOR2 SP140

2.42e-03121162IPR010919
DomainZnf_PHD

KDM5C CHD3 KMT2D SP140

2.49e-03911164IPR001965
DomainZF_PHD_2

KDM5C CHD3 KMT2D SP140

2.91e-03951164PS50016
DomainZF_PHD_1

KDM5C CHD3 KMT2D SP140

3.02e-03961164PS01359
Domain-

KDM5C ARID1A

3.81e-031511621.10.150.60
DomainBRIGHT

KDM5C ARID1A

3.81e-03151162SM00501
DomainARID_dom

KDM5C ARID1A

3.81e-03151162IPR001606
DomainARID

KDM5C ARID1A

3.81e-03151162PS51011
DomainARID

KDM5C ARID1A

3.81e-03151162PF01388
Domain-

CTTNBP2 ANK2 ANK3 TRANK1 CASKIN1 ANKRD11

4.54e-0324811661.25.40.20
DomainANK

CTTNBP2 ANK2 ANK3 TRANK1 CASKIN1 ANKRD11

4.82e-032511166SM00248
DomainAMP-bd_C

ACSM2A ACSM2B

4.89e-03171162IPR025110
DomainAMP-binding_C

ACSM2A ACSM2B

4.89e-03171162PF13193
DomainANK_REPEAT

CTTNBP2 ANK2 ANK3 TRANK1 CASKIN1 ANKRD11

5.00e-032531166PS50088
DomainAnkyrin_rpt-contain_dom

CTTNBP2 ANK2 ANK3 TRANK1 CASKIN1 ANKRD11

5.10e-032541166IPR020683
DomainANK_REP_REGION

CTTNBP2 ANK2 ANK3 TRANK1 CASKIN1 ANKRD11

5.10e-032541166PS50297
DomainAnkyrin_rpt

CTTNBP2 ANK2 ANK3 TRANK1 CASKIN1 ANKRD11

5.91e-032621166IPR002110
DomainGAGE

PAGE2 PAGE2B

6.10e-03191162IPR031320
DomainGAGE

PAGE2 PAGE2B

6.10e-03191162SM01379
PathwayBIOCARTA_HSWI_SNF_PATHWAY

ARID1A SMARCC1 SMARCC2

3.59e-0512793M22006
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

ATXN2L KDM5C NASP CHD3 ZNF318 GPATCH8 WRAP53 WWC2 KMT2D ZC3H4 MAP4K1 EIF4G1 SMARCC1 SMARCC2 TIMELESS OXSR1 SNX2

1.97e-097741221715302935
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NES SLK CTTNBP2 ANK2 ANK3 WDR7 ZNF318 AKAP12 AGO3 ZC3H4 CASKIN1 EIF4G1 PLCB1 SMARCC1 SMARCC2 MTCL1 BSN FOXG1

7.84e-099631221828671696
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TFEB ATXN2L NES NAA15 GIGYF1 MAST2 WWC2 FRMD6 MAP4K1 AHNAK EIF4G1 ANKRD11 RAB11FIP5 CEP152 MTCL1 SNX2 AHNAK2

9.55e-098611221736931259
Pubmed

Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development.

ARID1A SMARCC1 SMARCC2 FOXG1

9.98e-098122426986003
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

ATXN2L NES SLK NASP CHD3 ZNF318 CDC37 AHNAK EIF4G1 AHNAK2

2.62e-082561221033397691
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ATXN2L SLK NAA15 ANK2 GPATCH1 U2SURP NASP CHD3 TACC2 ZNF318 AKAP12 CDC37 CRACD ZC3H4 AHNAK SCIN AHNAK2

3.12e-089341221733916271
Pubmed

Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).

CHD3 ARID1A SMARCC1 SMARCC2

2.54e-0716122411784859
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

HTRA1 VPS72 KDM5C CHD3 ZNF318 GIGYF1 ARID1A MAST2 ABCA7 AGO3 ZC3H4 MCM3AP SMARCC1 RAB11FIP5 SMARCC2 CLSPN SP140

3.88e-0711161221731753913
Pubmed

p300/CREB binding protein-related protein p270 is a component of mammalian SWI/SNF complexes.

ARID1A SMARCC1 SMARCC2

4.19e-07512239584200
Pubmed

Characterization of the murine orthologue of a novel human subtelomeric multigene family.

WASH6P WASH3P WASH4P

4.19e-075122311701968
Pubmed

The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo.

ARID1A SMARCC1 SMARCC2

4.19e-075122318086889
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

SLK ANK2 LEMD3 NASP AKAP12 PREB AHNAK EIF4G1 RAB11FIP5 RAB15 SNX2

5.71e-074491221131732153
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

NAA15 LEMD3 U2SURP TACC2 WRAP53 ARID1A AKAP12 PREB FANCE ZC3H4 AHNAK EIF4G1 SMARCC1 SMARCC2 TIMELESS CEP152 MTCL1

6.24e-0711551221720360068
Pubmed

Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.

ARID1A SMARCC1 SMARCC2

8.36e-076122316940996
Pubmed

Variations in the composition of mammalian SWI/SNF chromatin remodelling complexes.

ARID1A SMARCC1 SMARCC2

8.36e-076122319650111
Pubmed

Human subtelomeric WASH genes encode a new subclass of the WASP family.

WASH6P WASH3P WASH4P

8.36e-076122318159949
Pubmed

The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest.

ARID1A SMARCC1 SMARCC2

8.36e-076122316230384
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

TFEB ATXN2L VPS72 KDM5C TACC2 ZNF318 ARID1A MCM3AP RAB11FIP5 BSN CLSPN SCIN

1.17e-065881221238580884
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ATXN2L VPS72 LIN28B LEMD3 GPATCH1 U2SURP CHD3 ZNF318 ARID1A ZC3H4 AHNAK EIF4G1 ANKRD11 SMARCC1 SMARCC2

1.35e-069541221536373674
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

KDM5C CHD3 ARID1A KMT2D ANKRD11 SMARCC1 SMARCC2

1.45e-06157122730186101
Pubmed

WASH maintains NKp46+ ILC3 cells by promoting AHR expression.

ARID1A WASH6P WASH3P

1.46e-067122328589939
Pubmed

The assembly of mammalian SWI/SNF chromatin remodeling complexes is regulated by lysine-methylation dependent proteolysis.

ARID1A SMARCC1 SMARCC2

2.33e-068122336335117
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ARID1A KMT2D PLCB1 SMARCC1 RAB11FIP5 SMARCC2 FGD5 MTCL1 BSN DNAAF1 ARHGAP45 AHNAK2

2.72e-066381221231182584
Pubmed

mSWI/SNF (BAF) Complexes Are Indispensable for the Neurogenesis and Development of Embryonic Olfactory Epithelium.

NES SMARCC1 SMARCC2 FOXG1

2.76e-0628122427611684
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

KDM5C CHD3 ARID1A ZC3H4 AHNAK EIF4G1 ANKRD11 MTCL1 AHNAK2

2.80e-06332122937433992
Pubmed

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

ATXN2L ARID1A SMARCC1 SMARCC2

3.20e-0629122436800290
Pubmed

Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.

NES ARID1A SMARCC1 SMARCC2 FOXG1

3.41e-0665122526655900
Pubmed

The BAF chromatin complex component SMARCC1 does not mediate GLI transcriptional repression of Hedgehog target genes in limb buds.

ARID1A SMARCC1 SMARCC2

3.48e-069122337805104
Pubmed

Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling.

ARID1A SMARCC1 SMARCC2

3.48e-06912239845365
Pubmed

Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B.

ARID1A SMARCC1 SMARCC2

3.48e-069122320086098
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ATXN2L SLK VPS72 ANK3 NASP ZNF318 ARID1A KMT2D AHNAK SMARCC1 SNX2

3.97e-065491221138280479
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

U2SURP ZNF318 GIGYF1 KMT2D MCM3AP ARHGAP29 CEP152

4.15e-06184122732908313
Pubmed

Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.

ARID1A SMARCC1 SMARCC2

4.96e-0610122312665591
Pubmed

A methylation-mediator complex in hormone signaling.

ARID1A SMARCC1 SMARCC2

4.96e-0610122314729568
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

ATXN2L NES SPAG1 SLK NAA15 OGFR TCEAL4 NASP ARID1A AKAP12 CDC37 PARP10 AHNAK EIF4G1 SMARCC1 OXSR1 AHNAK2

6.01e-0613671221732687490
Pubmed

Functional selectivity of recombinant mammalian SWI/SNF subunits.

ARID1A SMARCC1 SMARCC2

6.81e-0611122311018012
Pubmed

Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.

ARID1A SMARCC1 SMARCC2

6.81e-0611122318003620
Pubmed

SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones.

ARID1A SMARCC1 SMARCC2

9.05e-0612122311734557
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

ATXN2L NAA15 OGFR AKAP12 CDC37 AGO3 AHNAK EIF4G1 SMARCC1 SMARCC2

1.02e-054941221026831064
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

ATXN2L NES SLK HTRA1 CTTNBP2 ANK2 ANK3 WDR7 CHD3 ARID1A CRACD CASKIN1 VCAN EIF4G1 SMARCC2 BSN SNX2

1.09e-0514311221737142655
Pubmed

A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice.

SMARCC1 SMARCC2 FOXG1

1.17e-0513122324170322
Pubmed

Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex.

ARID1A SMARCC1 SMARCC2

1.17e-0513122311726552
Pubmed

Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1.

ARID1A SMARCC1 SMARCC2

1.17e-0513122317340523
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

ATXN2L KDM5C NASP TACC2 GIGYF1 ZC3H4 EIF4G1 TIMELESS MTCL1 SNX2

1.19e-055031221016964243
Pubmed

The Swi3 protein plays a unique role in regulating respiration in eukaryotes.

SMARCC1 SMARCC2

1.22e-052122227190130
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

1.22e-052122219634011
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

1.22e-052122215007166
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

1.22e-052122216521160
Pubmed

Genomic organization of the human cholesterol-responsive ABC transporter ABCA7: tandem linkage with the minor histocompatibility antigen HA-1 gene.

ABCA7 ARHGAP45

1.22e-052122211095984
Pubmed

Clinical significance of syndecan-1 and versican expression in human epithelial ovarian cancer.

VCAN SDC1

1.22e-052122220204274
Pubmed

The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.

ANK2 ANK3

1.22e-052122211781319
Pubmed

Structural basis of diverse membrane target recognitions by ankyrins.

ANK2 ANK3

1.22e-052122225383926
Pubmed

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.

AHNAK AHNAK2

1.22e-052122220833135
Pubmed

Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.

TFEB PSEN1

1.22e-052122226923592
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

1.22e-052122229948332
Pubmed

Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner.

TIMELESS CLSPN

1.22e-052122230796221
Pubmed

Foxg1 Antagonizes Neocortical Stem Cell Progression to Astrogenesis.

NES FOXG1

1.22e-052122230821834
Pubmed

Homozygosity for the 168His variant of the minor histocompatibility antigen HA-1 is associated with reduced risk of primary Sjögren's syndrome.

ABCA7 ARHGAP45

1.22e-052122215593299
Pubmed

Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

ARID1A SMARCC1 SMARCC2

1.49e-051412238895581
Pubmed

Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth.

ANK2 ANK3 GJA8

1.86e-0515122330562487
Pubmed

Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways.

ARID1A SMARCC1 SMARCC2

1.86e-0515122323785148
Pubmed

Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation.

ARID1A SMARCC1 SMARCC2

1.86e-0515122311175787
Pubmed

PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes.

ARID1A SMARCC1 SMARCC2

1.86e-0515122315985610
Pubmed

Regulation of dendritic development by neuron-specific chromatin remodeling complexes.

ARID1A SMARCC1 SMARCC2

1.86e-0515122317920018
Pubmed

An essential switch in subunit composition of a chromatin remodeling complex during neural development.

ARID1A SMARCC1 SMARCC2

1.86e-0515122317640523
Pubmed

The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression.

ARID1A SMARCC1 SMARCC2

1.86e-0515122311263494
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

SLK NAA15 CHD3 GIGYF1 MAST2 PREB WASH6P ZC3H4 SMARCC1 TIMELESS CLSPN

1.92e-056501221138777146
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

ANK3 WDR7 LEMD3 GPATCH1 ZNF318 AKAP12 FRMD6 ZC3H4 CD99 AHNAK RAB11FIP5 CLSPN

1.96e-057771221235844135
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

SLK NAA15 VPS72 U2SURP NASP CHD3 WRAP53 PREB ZC3H4 OXSR1 BSN

2.01e-056531221133742100
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ATXN2L NES NAA15 U2SURP ZNF318 ARID1A AHNAK MCM3AP EIF4G1 SMARCC1 SMARCC2

2.01e-056531221122586326
Pubmed

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

ALKBH2 NASP ARID1A FANCE TIMELESS CLSPN

2.02e-05157122630686591
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

ATXN2L CTTNBP2 U2SURP CRACD AHNAK VCAN EIF4G1

2.04e-05235122730258100
Pubmed

Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers.

ANK2 BFSP1 AHNAK

2.28e-0516122321745462
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

CTTNBP2 ANK2 ALKBH2 TACC2 GPATCH8 MAST2 TBC1D16 TRANK1 ZC3H4 CD99 VCAN CNPY3 RAB15 CEP152 ARHGAP45

2.42e-0512151221515146197
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

LEMD3 KDM5C GPATCH1 ZNF318 AHNAK MTCL1 CLSPN

2.46e-05242122734011540
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

ATXN2L VPS72 LEMD3 GPATCH1 ZNF318 GPATCH8 ARID1A SMARCC1 SMARCC2

2.65e-05440122934244565
Pubmed

The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes.

ARID1A SMARCC1 SMARCC2

2.76e-0517122311078522
Pubmed

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

ARID1A SMARCC1 SMARCC2

2.76e-0517122312368262
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

AOC1 ANK3 ICA1 NASP CHD3 TACC2 ZNF318 PABPN1L GPATCH8 AKAP12 WWC2 VCAN SMARCC1 TIMELESS

2.82e-0510841221411544199
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

ATXN2L GPATCH1 CHD3 ARID1A KMT2D ZC3H4 MCM3AP SMARCC2

2.87e-05341122832971831
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

ATXN2L SPAG1 SLK ANK3 CD99 AHNAK EIF4G1 ARHGAP29 PALM3 SNX2

3.20e-055651221025468996
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ATXN2L ANK2 WDR7 SH2D5 CASKIN1 PLCB1 RAB11FIP5 BSN

3.25e-05347122817114649
Pubmed

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

ARID1A SMARCC1 SMARCC2

3.31e-0518122328068325
Pubmed

BAF complexes facilitate decatenation of DNA by topoisomerase IIα.

ARID1A SMARCC1 SMARCC2

3.31e-0518122323698369
Pubmed

mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.

ARID1A SMARCC1 SMARCC2

3.31e-0518122314559996
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TFEB FGFRL1 WRAP53 ARID1A MAST2 ABCA7 TBC1D16 KMT2D AHNAK CASKIN1 MCM3AP EIF4G1 ANKRD11 AHNAK2

3.48e-0511051221435748872
Pubmed

The niche factor syndecan-1 regulates the maintenance and proliferation of neural progenitor cells during mammalian cortical development.

NES SDC1

3.65e-053122222936997
Pubmed

The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

ANK2 ANK3

3.65e-053122215611082
Pubmed

WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.

WASH6P WASH3P

3.65e-053122230425062
Pubmed

Single-cell Sequencing Reveals Variants in ARID1A, GPRC5A and MLL2 Driving Self-renewal of Human Bladder Cancer Stem Cells.

ARID1A KMT2D

3.65e-053122227387124
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK AHNAK2

3.65e-053122221940993
Pubmed

BAF chromatin remodeling complex: cortical size regulation and beyond.

SMARCC1 SMARCC2

3.65e-053122223974113
Pubmed

The C-terminal region of CHD3/ZFH interacts with the CIDD region of the Ets transcription factor ERM and represses transcription of the human presenilin 1 gene.

PSEN1 CHD3

3.65e-053122217489097
Pubmed

Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.

WASH6P WASH3P

3.65e-053122238086439
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK2 ANK3

3.65e-053122233410423
Pubmed

Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiation.

ARID1A SMARCC1

3.65e-053122236931659
Pubmed

The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.

CHD3 KMT2D

3.65e-053122226551667
Pubmed

WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.

WASH6P WASH3P

3.65e-053122225225459
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK2 ANK3

3.65e-053122234289389
Pubmed

The Transcription Factor EB Reduces the Intraneuronal Accumulation of the Beta-Secretase-Derived APP Fragment C99 in Cellular and Mouse Alzheimer’s Disease Models.

TFEB PSEN1

3.65e-053122232408680
InteractionANPEP interactions

NIBAN1 AKAP12 PREB WASH3P CD99 PLCB1 CNPY3 RAB11FIP5 AHNAK2

1.07e-061741219int:ANPEP
InteractionSMAD3 interactions

ATXN2L NAA15 ANK3 LEMD3 ALKBH2 KDM5C ARID1A MCM3AP SMARCC1 RAB11FIP5 SMARCC2 FOXG1 SERTAD1

2.95e-0644712113int:SMAD3
InteractionPHLPP1 interactions

ATXN2L NES SLK NASP CHD3 ZNF318 ARID1A CDC37 AHNAK EIF4G1 AHNAK2

5.39e-0633312111int:PHLPP1
InteractionNUP43 interactions

VPS72 KDM5C GPATCH1 CHD3 ZNF318 GPATCH8 ARID1A KMT2D MCM3AP EIF4G1 ANKRD11 SMARCC1 TIMELESS AHNAK2

2.35e-0562512114int:NUP43
InteractionTERF2IP interactions

VPS72 OGFR KDM5C U2SURP NASP CHD3 ZNF318 ARID1A ZC3H4 ANKRD11 SMARCC1 SMARCC2 CLSPN

2.80e-0555212113int:TERF2IP
GeneFamilyWiskott-Aldrich Syndrome protein family

WASH6P WASH3P WASH4P

5.37e-051685314
GeneFamilyPHD finger proteins

KDM5C CHD3 KMT2D SP140

8.55e-049085488
GeneFamilyAnkyrin repeat domain containing

CTTNBP2 ANK2 ANK3 TRANK1 CASKIN1 ANKRD11

9.79e-04242856403
GeneFamilyAT-rich interaction domain containing

KDM5C ARID1A

2.20e-0315852418
CoexpressionGSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP

NIBAN1 GALM KDM5C MAST2 TRANK1 CD99 AHNAK SP140

4.57e-062001228M6514
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000

TFEB NIBAN1 HTRA1 GALM ANK3 LIN28B ALKBH2 MYT1 CHD3 CRACD FRMD6 PLCB1 RAB11FIP5 DMRTA2 RAB15 MTCL1 FOXG1 SP140

8.16e-0698411818Facebase_RNAseq_e10.5_Olfactory Pit_1000
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

TCEAL4 STAC AKAP12 TFR2 CRACD FRMD6 FGD5

9.20e-0718912272157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CTTNBP2 ANK2 AKAP12 FRMD6 ACSM2A ACSM2B

6.54e-061661226c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellSevere-B_memory-6|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

TFEB DYNLT2B ANK3 CRACD CD99 SP140

7.00e-06168122685a36e1b994a8fd2f589563f011913e4944dc1cd
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D122|Adult / Lineage, Cell type, age group and donor

HTRA1 ICA1 BFSP1 MAP4K1 ARHGAP29 RAB11FIP5

7.49e-061701226a99cb3d21f8eb926886340ea99491e078e607648
ToppCellnormal-na-Lymphocytic_T-T4_em-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

NIBAN1 GALM ANK3 AKAP12 CD99 AHNAK

7.75e-06171122661318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 AKAP12 ARHGAP29 RAB11FIP5 ACSM2A ACSM2B

1.25e-05186122630dd4164c101006c8d95922d89652b82dbe4b5ea
ToppCell3'-Child04-06-SmallIntestine-Endothelial-lymphatic_endothelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CTTNBP2 AKAP12 ARHGAP29 RAB11FIP5 ACSM2A ACSM2B

1.25e-051861226eeacf59a9e6bf1c9fd59b6b13d35e8abae228cf0
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.25e-051861226903af26a63ec4b1755ab5cb81dfeb8dbd14bc5db
ToppCelldroplet-Kidney-nan-3m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES TIMELESS FGD5 SCIN FOXG1 SERTAD1

1.33e-05188122667c04f446fa4528b13a381622e88eb1f314cc6d5
ToppCelldroplet-Kidney-nan-3m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES TIMELESS FGD5 SCIN FOXG1 SERTAD1

1.33e-05188122603a7f6538cfddc230c0eab10c3613929addd7e33
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANK2 MYT1 STAC ARHGDIG SKOR2 BSN

1.37e-051891226cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NES NIBAN1 STAC INKA2 MTMR7 SDC1

1.41e-0519012261ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ANK3 DNAAF1 CCDC17 FOXG1 IQCG

1.41e-0519012262fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.50e-051921226be592e661367affced9ebe80849b466e6adb3a34
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.54e-051931226e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.54e-0519312260b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES NIBAN1 HTRA1 ANK2 NASP CLSPN

1.54e-051931226f25bdd10ef531b8d8441ea84573078b4b1b0f105
ToppCellASK440-Epithelial-Ciliated|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.54e-051931226a0baa8be6f590b2031fede22be588715ae458e93
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.59e-0519412263cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCellASK440-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.59e-051941226c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.59e-051941226b4ce60c06568123008b1081d644733cb91c28f51
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.59e-0519412267a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.63e-0519512260e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.63e-051951226db4270c135c392ed443670981656e3cd5b95939d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.63e-0519512266365e3893e38231090ec2dbef010dec71dea3d07
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.63e-0519512269651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCelldistal-Endothelial-Lymphatic-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HTRA1 AKAP12 FRMD6 RAB11FIP5 ACSM2A ACSM2B

1.63e-051951226f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCellmild-Myeloid-Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 GALM PARP10 TRANK1 DNAAF1 SP140

1.68e-051961226ded44b38ea489946e9eedfe752b5a9fde9149c16
ToppCelldistal-Endothelial-Lymphatic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HTRA1 AKAP12 FRMD6 RAB11FIP5 ACSM2A ACSM2B

1.68e-0519612263e8a20e1d163dcbd3bbd99fe179d54af02298af0
ToppCellNS-critical-d_0-4-Epithelial-Ciliated-diff|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.73e-05197122662e20ef825b92908d7732aa625dcff7b95ef6ca8
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 ANK3 AHNAK DNAAF1 CCDC17 IQCG

1.78e-051981226d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 GIGYF1 GPATCH8 AKAP12 AHNAK VCAN

1.83e-051991226174f6013af6eafa577f84205a62927f2b367fda3
ToppCellASK452-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

SLK ABCA7 WWC2 AHNAK ARHGAP29 SDC1

1.83e-05199122648cafe44951908d03f3c6f3e185e9cbb86fb5b3b
ToppCelldistal-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NES IRF1 AKAP12 CD99 ARHGAP29 SERTAD1

1.89e-0520012267a355c3883fd409b2e0868164bb6e7ce4b745776
ToppCellnormal_Lung-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

HTRA1 IRF1 AKAP12 CD99 AHNAK SERTAD1

1.89e-0520012266d8f6a6b3f61c529fbed1376659641030abf4f2c
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.89e-0520012267cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DYNLT2B SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.89e-0520012268441e289377215a6877640946fe3f6de1f456502
ToppCellLPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NES WRAP53 CRACD CSRNP2 CEP152

4.50e-051421225b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NASP MAP4K1 CLSPN SNX2 SP140

5.84e-051501225d6b977dd47aa017f6ba762f0c505cd896caa523f
ToppCelltumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TFEB ZNF318 MAP4K1 ARHGAP45 SP140

6.61e-051541225e16f200391537aa1002b0079481b94e1fb86b9ad
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NIBAN1 ANK3 TACC2 PALM3 SDC1

8.40e-0516212255c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TFEB GALM WRAP53 HINFP BSN

8.90e-05164122554f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NES ANK3 LIN28B RFX6 TFR2

9.42e-051661225bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCellfacs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NES ANK3 LIN28B RFX6 TFR2

9.42e-0516612255e3b998d740b24f790fad37350d704ca0ea10b77
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AKAP12 CSRNP2 VCAN WEE2 CLSPN

1.02e-041691225335619507857383c3b0b507cdf05d786ed59e585
ToppCell356C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FGFRL1 BFSP1 FANCE FRMD6 ACSM2B

1.08e-0417112253d26ef58fe5231373d7df9ac79d225546918cf82
ToppCell356C-Lymphocytic-ILC-ILC-2|ILC / Donor, Lineage, Cell class and subclass (all cells)

ABCA7 BFSP1 FANCE FRMD6 ACSM2B

1.11e-0417212254977e1f4deae781750e27a8054deccd336cfb74a
ToppCell5'-Adult-LymphNode-Hematopoietic-T_cells-gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPATCH8 TFR2 FANCE SMARCC2 ARHGAP45

1.17e-041741225ccc79febfcf588d8294ffc712338be96de8a5033
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF318 MAP4K1 ARHGAP45 SNX2 SP140

1.17e-0417412257c8704766dd4c80250754b5ee9907b342b9c2623
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF318 MAP4K1 ARHGAP45 SNX2 SP140

1.17e-04174122526ca6ebaa0081108d44c01f8ca56a63724f1c99d
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF318 MAP4K1 ARHGAP45 SNX2 SP140

1.17e-0417412259aa2168d3bcef7cdc5a47442618cb8e9eb24c95b
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRANK1 CEP152 ACSM2A ARHGAP45 SP140

1.21e-041751225a3f8c54c77bce9b035a4835945ab341909be4946
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NES NIBAN1 NASP FRMD6 CLSPN

1.24e-0417612258eb91dcf55d4e3e28a72d447181bf6d2ad891fc6
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

AKAP12 FRMD6 ARHGAP29 PLCB1 ACSM2B

1.24e-04176122598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

AKAP12 FRMD6 ARHGAP29 PLCB1 ACSM2B

1.24e-041761225c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHB MAP4K1 CLSPN SDC1 IQCG

1.31e-0417812256178706db4a855d72abc156537604d575624df56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFHB MAP4K1 CLSPN SDC1 IQCG

1.31e-041781225f02076ece0fa899e620971c887ad4da7f48684ed
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES NIBAN1 HTRA1 NASP CLSPN

1.34e-041791225ff678e2f33c914e3dd0f338ada25f506c3e3c980
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYT1 RFX6 PABPN1L STAC WEE2

1.38e-0418012259db9899ca42455310e9b63df523fe6c4780abfb7
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BFSP1 CRACD PLCB1 DMRTA2 FOXG1

1.45e-041821225d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BFSP1 CRACD PLCB1 DMRTA2 FOXG1

1.45e-04182122592f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BFSP1 CRACD PLCB1 DMRTA2 FOXG1

1.45e-04182122502baca9a72c7b559c3e452693b3b134af804c868
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NASP MAP4K1 CLSPN SNX2 SP140

1.49e-041831225956ff95aef9c5521b6a3ba7ac6df0aad242c1c35
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

NIBAN1 CTTNBP2 SH2D5 FANCE AHNAK2

1.53e-041841225d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

AKAP12 FRMD6 ARHGAP29 PLCB1 FGD5

1.56e-0418512254a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP12 ARHGAP29 RAB11FIP5 ACSM2A ACSM2B

1.56e-0418512259de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AKAP12 ARHGAP29 RAB11FIP5 ACSM2A ACSM2B

1.56e-04185122518f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

AKAP12 FRMD6 ARHGAP29 PLCB1 FGD5

1.56e-04185122536ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ANK2 MYT1 RFX6 MTMR7 BSN

1.60e-041861225b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCellCiliated-cil-2|World / Class top

AOC1 ARHGDIG DNAAF1 CCDC17 IQCG

1.64e-041871225e2e58ba039b5355c03c3b448e750aa37b0ea6913
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

CTTNBP2 ARHGAP29 MTCL1 SCIN AHNAK2

1.64e-041871225f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCelltumor_Lung-Endothelial_cells-Lymphatic_ECs|tumor_Lung / Location, Cell class and cell subclass

HTRA1 AKAP12 FRMD6 ARHGAP29 ACSM2B

1.64e-04187122587ecdc5f24aced95a37e653429f0fc493ff4aa3e
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

CTTNBP2 ARHGAP29 MTCL1 SCIN AHNAK2

1.64e-041871225da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

DYNLT2B SPAG1 DNAAF1 CCDC17 IQCG

1.69e-0418812256833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellCiliated|World / Class top

AOC1 ARHGDIG DNAAF1 CCDC17 IQCG

1.69e-041881225cc9178361360b5800f96516ed6a65089c144b1ce
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)|390C / Donor, Lineage, Cell class and subclass (all cells)

HTRA1 AKAP12 FRMD6 ARHGAP29 FGD5

1.69e-041881225aa69e3f44d506f5ef358a3374ac5160d847c858f
ToppCell390C-Endothelial_cells-Endothelial-F_(Lymphatics)-|390C / Donor, Lineage, Cell class and subclass (all cells)

HTRA1 AKAP12 FRMD6 ARHGAP29 FGD5

1.69e-0418812251f40b959777d18ad88d239df8cca304f062ba04c
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DYNLT2B EFHB DNAAF1 CCDC17 AHNAK2

1.69e-041881225606907c865bd2f11bb6474932716550f7723d858
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

SPAG1 ANK3 TACC2 TIMELESS CLSPN

1.69e-041881225186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 ARHGDIG DNAAF1 CCDC17 IQCG

1.73e-041891225fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

NIBAN1 ANK2 ANK3 TACC2 MAST2

1.73e-0418912259c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

HTRA1 TACC2 TRANK1 MTCL1 AHNAK2

1.73e-041891225da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 EFHB DNAAF1 CCDC17 IQCG

1.73e-041891225b4b93bd10b7e3cc16e54ff73beac230f519c010a
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 ARHGDIG DNAAF1 CCDC17 IQCG

1.73e-041891225565063f9e3dd79164321f8a394bd12c176baf202
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

NIBAN1 ANK2 ANK3 TACC2 MAST2

1.73e-0418912250a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AOC1 ARHGDIG DNAAF1 CCDC17 IQCG

1.73e-041891225497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

NIBAN1 ANK2 ANK3 TACC2 MAST2

1.77e-04190122593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellwk_08-11-Epithelial-Proximal_epithelial-intermediate_neuroendocrine|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ANK2 RFX6 PABPN1L MTMR7 BSN

1.77e-0419012255f1863bce9400b7c932f0e4d0e012ec4e8d7e555
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES NIBAN1 HTRA1 AHNAK ANKRD11

1.77e-041901225d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DYNLT2B EFHB DNAAF1 CCDC17 IQCG

1.77e-041901225426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 CEP152 DNAAF1 IQCG

1.77e-041901225da60bcc4b59d8e3719d8201387d567594059b1a4
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 CEP152 DNAAF1 IQCG

1.77e-041901225827a1f4e4ac4beada262f4fb965dd74a447a8f4f
ToppCellmoderate-Epithelial-Ciliated-diff|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DYNLT2B EFHB DNAAF1 CCDC17 IQCG

1.81e-0419112256cdc6a0c0a1ce5a1ef550832319847f62e718975
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIBAN1 PABPN1L STAC INKA2 MTMR7

1.81e-041911225ff7874cc005760a8f3b2e8072fbe418b6bfacaa8
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNLT2B EFHB DNAAF1 CCDC17 IQCG

1.81e-0419112253e84c453e8a151c42808fe2935f1d732e180008c
ToppCellCOVID-19-lung-CD4+_Treg|COVID-19 / Disease (COVID-19 only), tissue and cell type

NIBAN1 ANK3 MAP4K1 ARHGAP45 SP140

1.81e-0419112255a4ad5ae5c2dbfb225158cb598ef649c26a48350
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

DYNLT2B MAST2 CEP152 DNAAF1 IQCG

1.81e-04191122537cf121e6e80760c8519075b7845b9029958a988
ToppCellmoderate-Epithelial-Ciliated-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DYNLT2B EFHB DNAAF1 CCDC17 IQCG

1.81e-041911225b1bb27aab6ec651b45d5eea0a6b61a1da0fc6204
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

DYNLT2B EFHB DNAAF1 CCDC17 IQCG

1.81e-0419112250c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNLT2B SPAG1 EFHB CCDC17 IQCG

1.81e-0419112253cffaa64b9e2410daa8ec1f91cf03e49b89b51e7
DrugCefadroxil [50370-12-2]; Up 200; 11uM; HL60; HT_HG-U133A

TFEB ATXN2L OGFR MYT1 CHD3 WRAP53 MAST2 CNPY3 SMARCC2

9.92e-0719612091323_UP
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

ARID1A SMARCC1 SMARCC2

4.89e-0691163DOID:1925 (implicated_via_orthology)
DiseaseX-21319 measurement

ACSM2A ACSM2B

1.53e-0521162EFO_0800807
Diseasetestosterone measurement

TFEB ATXN2L AOC1 ANK2 ANK3 FGFRL1 ZNF318 WRAP53 ARID1A ZC3H4 SKOR2 PLCB1 PALM3 CNPY3 DMRTA2 SDC1

3.99e-05127511616EFO_0004908
DiseaseX-11478 measurement

ACSM2A ACSM2B

4.58e-0531162EFO_0021242
DiseaseMalignant neoplasm of breast

ANK2 VPS72 TACC2 ZNF318 MAGEE1 ARID1A AKAP12 KMT2D ARHGAP29 PLCB1 TIMELESS FGD5 CLSPN MAGEC2

8.45e-05107411614C0006142
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

1.52e-0451162EFO_0800378
DiseaseSezary Syndrome

CHD3 ARID1A KMT2D

1.62e-04271163C0036920
Diseaseintellectual disability (implicated_via_orthology)

NAA15 ANK2 KDM5C PREB

2.22e-04751164DOID:1059 (implicated_via_orthology)
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

2.27e-0461162EFO_0800106
Diseaseacisoga measurement

SLC52A1 AOC1

3.18e-0471162EFO_0800068
Diseaseneutrophil count

NES VPS72 KDM5C IRF1 ARID1A MAST2 ABCA7 AKAP12 GJA8 RP1L1 ANKRD11 PLCB1 ARHGAP45 SNX2 SERTAD1

3.44e-04138211615EFO_0004833
Diseasecolorectal cancer (is_marker_for)

HTRA1 KDM5C WRAP53 ARID1A SMARCC1

3.99e-041571165DOID:9256 (is_marker_for)
Diseasesexual dimorphism measurement

ATXN2L AOC1 VPS72 LIN28B IRF1 ARID1A FANCE PARP10 TRANK1 ZC3H4 CASKIN1 ANKRD11 BSN

4.16e-04110611613EFO_0021796
DiseaseAlzheimer disease

PSEN1 ABCA7

4.22e-0481162cv:C0002395
DiseaseAlzheimer disease, educational attainment

ATXN2L ICA1 ABCA7 SKOR2 SMARCC1 BSN

4.46e-042471166EFO_0011015, MONDO_0004975
DiseaseNeurodevelopmental Disorders

ANK2 ZC3H4 ANKRD11 FOXG1

5.06e-04931164C1535926
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCC1 SMARCC2

5.42e-0491162DOID:0050340 (implicated_via_orthology)
Diseaseage at menarche

VPS72 LIN28B ARID1A TBC1D16 ZC3H4 SKOR2 EIF4G1 PLCB1 BSN

5.78e-045941169EFO_0004703
Diseaselymphocyte count

SLC52A1 AOC1 GALM TCEAL4 IRF1 GIGYF1 TFR2 TBC1D16 CDC37 AHNAK MCM3AP ANKRD11 PLCB1 ARHGAP45 SP140

6.26e-04146411615EFO_0004587
Diseasegastric adenocarcinoma (is_implicated_in)

IRF1 KMT2D

8.23e-04111162DOID:3717 (is_implicated_in)
Diseasereticulocyte measurement

PSEN1 U2SURP FGFRL1 IRF1 TFR2 ZC3H4 AHNAK EIF4G1 PLCB1 OXSR1 BSN ARHGAP45

9.14e-04105311612EFO_0010700
Diseaseintracranial aneurysm (is_implicated_in)

KMT2D VCAN

9.86e-04121162DOID:10941 (is_implicated_in)
Diseasealcohol use disorder (implicated_via_orthology)

KDM5C ARID1A MAP4K1 SMARCC1 SMARCC2

1.06e-031951165DOID:1574 (implicated_via_orthology)
DiseaseCoffin-Siris syndrome

ARID1A SMARCC2

1.16e-03131162C0265338
DiseaseN-acetyl-isoputreanine measurement

SLC52A1 AOC1

1.16e-03131162EFO_0800107
Diseaselymphocyte percentage of leukocytes

SPAG1 AOC1 IRF1 ARID1A ABCA7 PLCB1 ARHGAP45 SERTAD1 SP140

1.28e-036651169EFO_0007993
DiseaseAlzheimer's disease (implicated_via_orthology)

PSEN1 ANK2 PLCB1

1.48e-03571163DOID:10652 (implicated_via_orthology)
Diseaseresponse to irinotecan

PLCB1 OXSR1

1.56e-03151162EFO_0004829
DiseaseT-Cell Lymphoma

ARID1A KMT2D

1.77e-03161162C0079772
DiseaseCrohn's disease

SLC52A1 ANK2 IRF1 INKA2 CDC37 BSN SP140

1.83e-034411167EFO_0000384
Diseaseerythritol measurement

NASP MAST2

2.00e-03171162EFO_0021171
Diseaselung non-small cell carcinoma (is_implicated_in)

IRF1 WRAP53 ARID1A KMT2D

2.25e-031391164DOID:3908 (is_implicated_in)
DiseaseNuclear non-senile cataract

BFSP1 GJA8

2.25e-03181162C1112705
DiseaseNuclear cataract

BFSP1 GJA8

2.25e-03181162C0392557
Diseasehearing loss

ZNF318 MAST2 AHRR

2.36e-03671163EFO_0004238
Diseasevenous thromboembolism, fibrinogen measurement

ATXN2L IRF1 PARP10

2.36e-03671163EFO_0004286, EFO_0004623
Diseasestomach cancer (is_marker_for)

HTRA1 KDM5C ARID1A KMT2D

2.43e-031421164DOID:10534 (is_marker_for)
Diseasecortical surface area measurement

ATXN2L CTTNBP2 ANK3 LIN28B MYT1 FGFRL1 MAST2 TBC1D16 VCAN RP1L1 DMRTA2 MTCL1 FOXG1

2.45e-03134511613EFO_0010736
Diseasegamma-aminoisobutyric acid measurement

AOC1 TACC2

2.51e-03191162EFO_0010482
Diseasereticulocyte count

U2SURP FGFRL1 IRF1 MAST2 TFR2 ZC3H4 AHNAK PLCB1 PALM3 BSN ARHGAP45

2.78e-03104511611EFO_0007986
Diseaseserum non-albumin protein measurement

WRAP53 MAST2 TBC1D16 ARHGAP29 ARHGAP45 SP140

3.09e-033611166EFO_0004568
Diseaseesophagus squamous cell carcinoma (is_marker_for)

HTRA1 WRAP53 KMT2D

3.13e-03741163DOID:3748 (is_marker_for)
DiseaseFEV/FEC ratio

HTRA1 CTTNBP2 NAA15 U2SURP NASP IRF1 RFX6 FANCE WWC2 ANKRD11 MTCL1 CCDC17

3.29e-03122811612EFO_0004713
Diseaseserum gamma-glutamyl transferase measurement

PSEN1 ICA1 GPATCH1 ARID1A WWC2 TRANK1 AHNAK RP1L1 PALM3 DMRTA2

3.29e-0391411610EFO_0004532
Diseasecarnitine measurement

ANK3 ZNF318 PLCB1

3.38e-03761163EFO_0010469

Protein segments in the cluster

PeptideGeneStartEntry
LVLDPKGGSGDREEE

AHRR

366

A9YTQ3
EPTGEEPAVLGGDKE

ALKBH2

21

Q6NS38
TKEILGPEGGEGKEE

PABPN1L

36

A6NDY0
GGDIYVPEDPKLKDG

ALDH9A1

356

P49189
EEPLSGVKDRDEGLG

CCDC17

596

Q96LX7
DVQEPPVKDGGDLSD

CEP152

1556

O94986
ALPVAEPGLEDVKDG

ANKRD11

2026

Q6UB99
EPGLEDVKDGVDAVP

ANKRD11

2031

Q6UB99
PKEAVTPLDEQEGDG

VCAN

1056

P13611
KEESQLPGTGGPEDV

AKAP12

1051

Q02952
PVLGVKGEPGTEEGS

CSRNP2

426

Q9H175
DDKGNVLPPGTEGDI

ACSM2A

396

Q08AH3
DVVDIEGLGETPPAK

BAP18

151

Q8IXM2
PRLKSEDGVEGDLGE

AHNAK

131

Q09666
APDVSLEGPEGKLKG

AHNAK

1166

Q09666
DVEVPDVSLEGPEGK

AHNAK

1291

Q09666
DVSGPDIDIEGPEGK

AHNAK

2421

Q09666
DIDVSGPKVDIEGPD

AHNAK

2666

Q09666
GPKVDIEGPDVNIEG

AHNAK

2671

Q09666
IEGPDVNIEGPEGKL

AHNAK

2676

Q09666
GEGPDVDVNLPKADI

AHNAK

2781

Q09666
TGPKVEGDLKGPEVD

AHNAK

2856

Q09666
DVEGPDVNIEGPEGK

AHNAK

2931

Q09666
GPEVDVSGPKLNIEG

AHNAK

3331

Q09666
VEGDLKGPEVDIKGP

AHNAK

3696

Q09666
DIDVPDVNIEGPEGK

AHNAK

3841

Q09666
GEGPDVDVTLPKADI

AHNAK

4331

Q09666
EGDLKGPEIDIKGPS

AHNAK

4411

Q09666
SDLKGPEVDIEGPEG

AHNAK

4486

Q09666
GIDTPDIDIHGPEGK

AHNAK

4561

Q09666
VEGDLKGPEADIKGP

AHNAK

4746

Q09666
GLEGPDVDLQGPEAK

AHNAK

5216

Q09666
KEGEEADAPGVIPGI

CD99

116

P14209
DLDVTLPGEGGKDRP

AGO3

106

Q9H9G7
GEVDVVVLEDPLPGG

AOC1

256

P19801
EADKEEGEAAPAPGL

DMRTA2

291

Q96SC8
PVGLIKGEDKDEGPV

ATXN2L

636

Q8WWM7
EEQKEAGVGVDPAPG

ABCA7

2111

Q8IZY2
GEPPSTVEEEGIPKE

IQCG

26

Q9H095
AELEEEEGKPEGPAN

RAB15

191

P59190
EKGEDPELPGAVKSE

RFX6

61

Q8HWS3
GEEEGARLPEGKPVQ

RAB11FIP5

421

Q9BXF6
EEPEIDSPGGDIGLS

IRF1

276

P10914
PKREGPVGGESDSEE

MTCL1

766

Q9Y4B5
AGEKPLAAGPGEEEL

NOBOX

101

O60393
EKLGTEREGGEEPLG

PALM3

441

A6NDB9
LGVEKKGGEEEPEAT

PALM3

486

A6NDB9
KGGEEEPEATKEPLE

PALM3

491

A6NDB9
GVEGSDIPDDGKLIG

OXSR1

506

O95747
ELQTPPGKDGAVEDE

LEMD3

206

Q9Y2U8
GGEEEEELLGPKLEE

ARID1A

1761

O14497
DVKEGATGADPLPLE

ANK2

3146

Q01484
EGGDPEEKGVDRLLG

MMTAG2

106

Q9BU76
GEAGVEGPPLAKVEA

CASKIN1

1106

Q8WXD9
GELPTEGAGPDVVED

ARHGAP45

101

Q92619
LILGGPEEEEVPSGV

MAGEC2

61

Q9UBF1
DSEGPKGAEGPIEFE

MAGEE1

446

Q9HCI5
SEGLEEEGPEAGGKE

GIGYF1

341

O75420
DLPELEKGGEKGETG

INKA2

171

Q9NTI7
GNLDGDPKEISPVID

MTMR7

386

Q9Y216
LVPSPGGDAVEKEVE

MCM3AP

1501

O60318
GEEPGKLPEPAEEES

LIN28B

11

Q6ZN17
AVPEAPKGGEAEDLV

BSN

651

Q9UPA5
GTGLEPLEEGERPKK

GPATCH1

16

Q9BRR8
LDPGEPNKSKEVGGE

GPATCH8

606

Q9UKJ3
ELAPVGPDEKEKGAG

FOXG1

136

P55316
VLDDISPGKESLGPD

FGFRL1

116

Q8N441
KGGPADLAGLEDEDV

PDZK1P1

291

A8MUH7
VPLREDEPKDEGSVG

FGD5

71

Q6ZNL6
GLEAPPSEKEEGEEG

NES

1341

P48681
ALLKIEDEPGDGPDV

PAGE2B

76

Q5JRK9
DLPGTEGGTEGKIVP

GPR101

486

Q96P66
DPTVKPVDVGGDEPE

NASP

301

P49321
DDEEIGGPKEELIPE

NAA15

631

Q9BXJ9
GQPKEDSEELGLPDV

ARHGAP29

1221

Q52LW3
RISPDGEEGYPGELK

GALM

131

Q96C23
GIEADTKPRDTGPED

FRMD6

396

Q96NE9
EVIPDTPAEAGGLKE

HTRA1

416

Q92743
LLADKEGGPPAVDEV

ARHGDIG

26

Q99819
AKEGEEAGPGDPLLE

CDC37

351

Q16543
LDGGEESPEGISKPV

CTTNBP2

886

Q8WZ74
TPGERGEEKPLDGQE

CHD3

1646

Q12873
PPAEEGAEPEVGEKK

GJA8

336

P48165
PIDKEIEPDGAELEG

BFSP1

541

Q12934
RKELGGLEGDPSPEE

CNPY3

246

Q9BT09
GDTEPLLKQEGPVEA

CRACD

486

Q6ZU35
VIEEEGKVGPDEDKP

ANK3

3466

Q12955
AGEAESEKGGEELLP

EIF4G1

471

Q04637
EERTGPAGPEGKEQD

MAST2

46

Q6P0Q8
VEAKREDGGPEPEGT

DNAAF1

401

Q8NEP3
PVEVKGEDGDGEPEG

DNAAF1

426

Q8NEP3
KGEDGDQEPEGTLPA

DNAAF1

456

Q8NEP3
VKGEDGDREPEGTLP

DNAAF1

481

Q8NEP3
PLASGPEGVEELVGK

EFHB

146

Q8N7U6
KTLEEGLEGLEDAPP

FANCE

296

Q9HB96
TVPGEPGRKEEEEEG

HINFP

431

Q9BQA5
VGDGVPEAEKNAGEP

DYNLT2B

11

Q8WW35
EEPPDGGTDGKAQLV

PARP10

696

Q53GL7
ALLKIEDEPGDGPDV

PAGE2

76

Q7Z2X7
GTPEPEGADKDDLLL

ICA1

361

Q05084
EEDTEGRTGPKEGTP

OGFR

501

Q9NZT2
KGPSIGDIEDEEPEL

MAP4K1

296

Q92918
DIEIGVSDPEKVGDG

SNX2

141

O60749
VKQELPSEEGPGEAL

TFEB

346

P19484
GPEAGGTKEVPIKEI

SLK

591

Q9H2G2
PEPTESGDEGEELGL

WRAP53

486

Q9BUR4
GEDPEERGVKLGLGD

PSEN1

371

P49768
IKVLGEKPELPDGGD

SCIN

221

Q9Y6U3
EKPELPDGGDDDDII

SCIN

226

Q9Y6U3
LPAEGLVGSGKELPE

SH2D5

201

Q6ZV89
GEGPKEGEAVVLPEV

SDC1

96

P18827
GPGKEEAPELDEAEL

SERTAD1

201

Q9UHV2
CIAGTGPDEPEKLEG

SMARCC1

761

Q92922
GPDEPEKLEGAEEEK

SMARCC1

766

Q92922
EPKEPREGGGAIEEE

SMARCC2

771

Q8TAQ2
TPAEEDGGGKIDLIE

PM20D2

161

Q8IYS1
GVPIKSLDDDLDGVP

U2SURP

726

O15042
VPAPGAKDEDDGVIL

BCO1

461

Q9HAY6
SPEEKEEGELIGPVG

AHNAK2

5741

Q8IVF2
DDKGNVLPPGTEGDI

ACSM2B

396

Q68CK6
LEGEGPQNPEETDEK

CLSPN

456

Q9HAW4
EGEIEDLALGPDGKL

PREB

196

Q9HCU5
EGKPEIEGKPESEGE

TCEAL4

91

Q96EI5
IEGKPESEGEPGSET

TCEAL4

96

Q96EI5
GLASPEEEDAVGKEP

TIMELESS

1146

Q9UNS1
KAQGETDLPPGVLED

WWC2

1101

Q6AWC2
VKEGEGGQESFPELP

NIBAN1

911

Q9BZQ8
PEDPILGEDEVGGNK

RNASE10

81

Q5GAN6
EEGLKEEGLPEEGSV

RP1L1

1391

Q8IWN7
DVEKEPEGGAGVIPS

SMTNL1

256

A8MU46
PELQLGSPGAEEEEK

SLC52A1

231

Q9NWF4
TKPEPEDDAEEGLGG

WASH4P

161

A8MWX3
VNEGKEEPGRPAGEV

SPAG1

761

Q07617
GVDGLPKEAVGAEQP

STAC

11

Q99469
PAPEDEEKLAQGLGV

TBC1D16

156

Q8TBP0
TKPEPEDDAEEGLGG

WASH3P

146

C4AMC7
GEVADTPLEPGKVAG

TACC2

1686

O95359
EELGGDIPGKEFDTP

PLCB1

1201

Q9NQ66
VEGHKPPEGEEEEEG

SKOR2

746

Q2VWA4
KGSGPPPTEEEEGER

ZC3H4

916

Q9UPT8
EGEPEKELSLLPGEG

SP140

371

Q13342
KELSLLPGEGEEGSD

SP140

376

Q13342
IRGDLEEAGPEEGKG

WEE2

176

P0C1S8
LVGEPGPKEENVDIE

VPS72

221

Q15906
GPKEENVDIEGLDPA

VPS72

226

Q15906
EVEPGKESPGGEEEE

TRANK1

1076

O15050
GVIGAEFGAEIEPPK

WDR7

1131

Q9Y4E6
EAGKVGEQLPLEDPD

TFR2

216

Q9UP52
DISPEKSELDLGEPG

ZNF318

1711

Q5VUA4
KPEPEDDAEEGLGGL

WASH6P

131

Q9NQA3
GGEGDDPAREELEPK

KDM5C

1466

P41229
LEGPVSPDVEPGKEE

KMT2D

1666

O14686
EEDLGQAAKPGPGIV

MYT1

181

Q01538